CN114502207A - 包含多种硬化状态的植入物 - Google Patents

包含多种硬化状态的植入物 Download PDF

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Publication number
CN114502207A
CN114502207A CN202080068787.9A CN202080068787A CN114502207A CN 114502207 A CN114502207 A CN 114502207A CN 202080068787 A CN202080068787 A CN 202080068787A CN 114502207 A CN114502207 A CN 114502207A
Authority
CN
China
Prior art keywords
implant
crosslinking
medical grade
polymeric material
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202080068787.9A
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English (en)
Chinese (zh)
Inventor
罗伊·考夫曼
尼姆罗德·考夫曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Saitborn Medical Co ltd
Original Assignee
Saitborn Medical Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Saitborn Medical Co ltd filed Critical Saitborn Medical Co ltd
Publication of CN114502207A publication Critical patent/CN114502207A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/502—Plasticizers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y70/00—Materials specially adapted for additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
CN202080068787.9A 2019-08-26 2020-08-25 包含多种硬化状态的植入物 Pending CN114502207A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962891460P 2019-08-26 2019-08-26
US62/891,460 2019-08-26
PCT/IL2020/050928 WO2021038562A1 (en) 2019-08-26 2020-08-25 Implant comprising a plurality of hardening states

Publications (1)

Publication Number Publication Date
CN114502207A true CN114502207A (zh) 2022-05-13

Family

ID=72521685

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080068787.9A Pending CN114502207A (zh) 2019-08-26 2020-08-25 包含多种硬化状态的植入物

Country Status (5)

Country Link
US (1) US12611483B2 (https=)
EP (1) EP4021521A1 (https=)
JP (1) JP2022545893A (https=)
CN (1) CN114502207A (https=)
WO (1) WO2021038562A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021038562A1 (en) * 2019-08-26 2021-03-04 Setbone Medical Ltd. Implant comprising a plurality of hardening states
JP2024537823A (ja) * 2021-09-29 2024-10-16 セットボーン メディカル リミテッド 加速された現場硬化特性を有する即時使用可能なモノマーを含まないアクリル骨セメント

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1419656A (zh) * 2000-03-24 2003-05-21 诺瓦提斯公司 可交联或可聚合的预聚物
US20050271727A1 (en) * 2004-06-07 2005-12-08 Callisyn Pharmaceuticals, Inc. Biodegradable and biocompatible crosslinked polymer hydrogel prepared from PVA and/or PEG macromer mixtures
CN1842350A (zh) * 2003-07-25 2006-10-04 Sdgi控股股份有限公司 包含胶原和脱矿骨基质的交联组合物
CN102573944A (zh) * 2009-07-02 2012-07-11 亚洲大学校产学协力团 原位成型水凝胶及其生物医学用途
CN103223188A (zh) * 2012-01-30 2013-07-31 赫罗伊斯医疗有限责任公司 糊状骨水泥
WO2018185770A1 (en) * 2017-04-05 2018-10-11 Setbone Medical Ltd. Property changing implant

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2027921C (en) 1989-10-19 1997-12-09 Nobuo Nakabayashi Bone cement composition, cured product thereof, implant material and process for the preparation of the same
US5538514A (en) 1994-04-07 1996-07-23 Zimmer, Inc. Method for forming bone cement to an implant
CN1538827A (zh) * 2001-03-21 2004-10-20 用于制造可成形的体内植入物的组合物和方法、以及由此制造出的植入物
WO2005065079A2 (en) * 2003-11-10 2005-07-21 Angiotech International Ag Medical implants and fibrosis-inducing agents
US20080206186A1 (en) * 2005-04-26 2008-08-28 Rimon Therapeutics Ltd. Pro-Angiogenic Polymer Scaffolds
EP2192886B1 (en) * 2007-08-28 2017-12-20 Pioneer Surgical Technology, Inc. Cement products and methods of making and using the same
DE102010003547A1 (de) * 2009-04-02 2010-10-14 Innotere Gmbh Bioaktiver Knochenzement und Verfahren zu seiner Herstellung
US8475536B2 (en) 2010-01-29 2013-07-02 DePuy Synthes Products, LLC Methods and devices for implants with improved cement adhesion
US8926710B2 (en) 2010-10-25 2015-01-06 Warsaw Orthopedic, Inc. Osteoinductive bone graft injectable cement
DE102012008815B4 (de) * 2012-05-07 2014-03-06 Heraeus Medical Gmbh Mischvorrichtung für Mehrkomponentensysteme
DE102016209988A1 (de) * 2016-06-07 2017-12-07 Heraeus Medical Gmbh Pastenförmiger Zweikomponenten-Polymethylmethacrylat-Knochenzement
DE102016212091A1 (de) * 2016-07-04 2018-01-04 Heraeus Medical Gmbh Antiseptischer Polymethylmethacrylat-Knochenzement
WO2021038562A1 (en) 2019-08-26 2021-03-04 Setbone Medical Ltd. Implant comprising a plurality of hardening states
CN114209872B (zh) 2021-09-14 2022-11-22 上海意久泰医疗科技有限公司 一种双组份糊剂、应用和骨水泥的制备方法
JP2024537823A (ja) 2021-09-29 2024-10-16 セットボーン メディカル リミテッド 加速された現場硬化特性を有する即時使用可能なモノマーを含まないアクリル骨セメント

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1419656A (zh) * 2000-03-24 2003-05-21 诺瓦提斯公司 可交联或可聚合的预聚物
CN1842350A (zh) * 2003-07-25 2006-10-04 Sdgi控股股份有限公司 包含胶原和脱矿骨基质的交联组合物
US20050271727A1 (en) * 2004-06-07 2005-12-08 Callisyn Pharmaceuticals, Inc. Biodegradable and biocompatible crosslinked polymer hydrogel prepared from PVA and/or PEG macromer mixtures
CN102573944A (zh) * 2009-07-02 2012-07-11 亚洲大学校产学协力团 原位成型水凝胶及其生物医学用途
CN103223188A (zh) * 2012-01-30 2013-07-31 赫罗伊斯医疗有限责任公司 糊状骨水泥
WO2018185770A1 (en) * 2017-04-05 2018-10-11 Setbone Medical Ltd. Property changing implant

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
韦军: "高分子合成工艺学", 华东理工大学出版社, pages: 10 - 12 *

Also Published As

Publication number Publication date
JP2022545893A (ja) 2022-11-01
EP4021521A1 (en) 2022-07-06
US20220288272A1 (en) 2022-09-15
WO2021038562A1 (en) 2021-03-04
US12611483B2 (en) 2026-04-28

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