CN114470022A - 猫眼部护理液及其制备方法和应用 - Google Patents
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Abstract
本发明属于兽用保健品技术领域，公开了一种猫眼部护理液及其制备方法和应用，该护理液是取复合氨基酸、洋甘菊提取液和硼酸经溶解混匀、无菌过滤工艺制得。本发明的制备工艺简单，制得的猫眼部护理液适用于猫眼部护理，可有效预防及辅助治疗猫眼部充血、肿胀、分泌物多等症状。本发明通过调整原料组分配比，提供针对猫生理特点的眼部护理液，解决现阶段猫眼部护理预防效果不佳、刺激性较大的问题。本发明的产品适用于猫眼部保健。
Description
技术领域
本发明属于兽用保健品技术领域，涉及一种眼部护理液及其制备方法和应用，具体地说是一种猫眼部护理液及其制备方法和应用。
背景技术
造成猫流泪的原因有很多，如食物过咸、异物、倒睫、感染疱疹病毒或者杯状病毒引发的炎症以及其它眼部疾病等。尤其波斯猫、异国短毛猫等品种，有眼睛占比大且圆，鼻短而扁宽，双眼之中有凹陷，凹陷为脸部圆心等面部特征。具有这些面部特征的猫鼻泪管曲度大、泪腺短，导致正常分泌泪水也无法负荷，往往溢至面部形成泪痕，也更易患泪管堵塞症。因此，为减少流泪、预防眼部疾病，需要对猫眼部日常清洗、护理。
现有猫眼部护理液往往含有水杨酸等刺激性成分或者含有牛磺酸等眼部护理液常用成分，未考虑到猫眼的结构、生理特性，并且仅能起到辅助治疗作用，并不能有效预防猫眼部疾病的发生。因此，通过改善护理液组成，发明一种更温和、成本较低、能够预防猫泪管堵塞症发生、缓解猫眼部充血、肿胀、分泌物多等症状的猫眼部护理液尤为重要。
发明内容
为解决现有技术中存在的以上不足，本发明旨在提供一种猫眼部护理液，以达到降低成本、更温和且贴合猫眼部特点、预防和辅助治疗猫眼部疾病的目的；
本发明的另一个目的，是要提供上述猫眼部护理液的一种制备方法；
本发明还有一个目的，是要提供上述猫眼部护理液的一种应用。
为实现上述目的，本发明所采用的技术方案如下：
一种猫眼部护理液，制成每100体积份的所述猫眼部护理液的原料，包括：复合氨基酸2.5-3.2重量份、硼酸1.6-2.3重量份、洋甘菊提取液2.5-3.2体积份；其中，重量份数与体积份数的比例关系为g：mL。
作为本发明的限定，所述复合氨基酸由谷氨酸、缬氨酸和亮氨酸混合而成。
作为本发明的进一步限定，所述复合氨基酸由1.4-2.5重量份的谷氨酸、0.3-1.3重量份的缬氨酸和0.8-2.1重量份的亮氨酸混合而成。
本发明还提供了上述猫眼部护理液的一种制备方法，它是取所有原料加入至注射用水，溶解混匀，无菌过滤，即得所述猫眼部护理液。
其中，无菌过滤过程，采用孔径0.22μm的无菌过滤器过滤。
本发明还提供了上述猫眼部护理液的一种应用，所述猫眼部护理液用于猫眼部护理，预防及辅助治疗猫眼部充血、肿胀、分泌物多等症状。
由于采用了上述的技术方案，本发明与现有技术相比，所取得的有益效果是：
（1）本发明的猫眼部护理液通过添加复合氨基酸，实现对猫眼部的营养、抑菌作用，起到预防眼部疾病的目的，其中，亮氨酸在护理液中起到促进皮肤、肌肉、眼部粘膜组织修复的作用；谷氨酸是治疗眼疾的药物，同时参与碳水化合物的代谢，保持皮肤与粘膜湿润，温和无刺激性；缬氨酸可以促进视神经系统功能正常，还可以保护肝脏，加速创伤愈合。三种氨基酸的配合更好地缓解猫眼部干痒、泛红、充血、肿胀、分泌物多等症状，且通过调节机体代谢起到预防眼部疾病的效果；
（2）本发明的猫眼部护理液结合猫的生理特性，选择添加必需氨基酸中的谷氨酸、缬氨酸和亮氨酸来调节代谢，相较于传统眼部护理液中的牛磺酸等成分，价格更低，且更易被猫吸收、代谢，快速补充营养，缓解眼部疲劳，作用效果更好，有效预防猫泪管堵塞症的发生；
（3）本发明的猫眼部护理液通过添加硼酸作为缓冲剂和抑菌剂，起到调节酸碱度的作用，使护理液具有与猫泪液近似的pH，降低刺激性，同时，还具有一定的抑菌作用。此外，硼酸也使护理液中的酸性氨基酸（谷氨酸）可以更好地发挥功效，两者共同维持护理液的pH；
（4）菊花具有散风清热、平肝明目的功效，本发明的猫眼部护理液添加的洋甘菊提取液较其它菊花提取物，缓解眼部粘膜、肌肉的充血、肿胀的效果更好；
（5）本发明的猫眼部护理液制备方法简单、易操作、适合工业生产；
综上所述，本发明的猫眼部护理液温和不刺激、成本较低、能够预防猫泪管堵塞症发生，缓解猫眼部充血、肿胀、分泌物多等症状；本发明的制备方法易于控制，适于工业生产；本发明的制备方法适用于制备猫眼部护理液，所制得猫眼部护理液适用于猫眼部护理。
具体实施方式
下面通过具体实施例对本发明做进一步详细说明，应当理解所描述的实施例仅用于解释本发明，并不限定本发明。
实施例1-6 猫眼部护理液的制备方法
实施例1-6分别为一种猫眼部护理液的制备方法，按如下步骤实施；
1）配制复合氨基酸
按照如表1所示的氨基酸配料关系分别预先配制实施例1-6中的复合氨基酸，将对应比例原料混匀，即得复合氨基酸；
2）配制猫眼部护理液
按照如表2所示的猫眼部护理液的原料分别配制实施例1-6的猫眼部护理液；其中，各实施例所用复合氨基酸已在步骤1）配制，按表2对应用量称取，搅拌；所用洋甘菊提取液购自广州中宏生物科技有限公司；使所有原料溶解混匀，采用孔径0.22μm的无菌过滤器过滤，分装，即得猫眼部护理液。
实施例7 猫眼部护理液的应用
实验一：猫眼部护理液用于预防眼部疾病
选择56只体况、体重一致的异国短毛猫，随机分成八组，分别为A1-A6组、对照组和空白组，共8组，每组7只，其中A1-A6组一一对应使用实施例1-6制备的猫眼部护理液M1-M6进行滴眼处理，对照组使用某市售含水杨酸的宠物眼部护理液进行滴眼处理，空白组使用生理盐水进行滴眼处理，每只猫1-2mL/次，一天2次，连续使用3个月，并记录眼部炎症发病率、眼部充血出现率、分泌物减少出现率；记录结果如表3所示：
由表3可知，使用本发明的猫眼部护理液的实验组猫眼部炎症发病率和眼睛充血出现率均明显低于空白组，而分泌物减少出现率均显著高于对照组和空白组；同时，实验组猫眼睛充血出现率不高于对照组。表明本发明的猫眼部护理液预防作用效果好于市售产品，能有效减少猫眼部分泌物产生，预防猫眼部炎症和眼睛充血，起到很好的眼部护理效果，有助于预防分泌物过多引起的猫泪管堵塞症的发生。
实验二：猫眼部护理液用于辅助治疗眼部疾病
眼部炎症等会使病猫产生眼部充血、肿胀或分泌物多等症状。从宠物医院陆续选择56只具有上述症状的猫，分为B1-B6组、C组和D组，共8组，每组7只，对B1-B6组和C组以相同方法使用红霉素眼药水进行常规治疗，同时，B1-B6组一一对应使用实施例1-6制备的猫眼部护理液M1-M6进行滴眼处理辅助治疗，C组使用生理盐水进行滴眼处理辅助治疗作为对照，D组不进行常规治疗，仅使用实施例1制备的猫眼部护理液M1进行滴眼处理作为对照，每只猫1-2mL/次，一天2次，连续使用1个月，并记录眼部炎症治愈率、眼部充血缓解率、眼部肿胀缓解率和分泌物增多缓解率；记录结果如表4所示：
由表4可知，使用本发明的猫眼部护理液辅助治疗的B1-B6组猫眼部炎症治愈率均明显高于C组和D组，同时，B1-B6组猫眼部充血缓解率、眼部肿胀缓解率和分泌物增多缓解率均高于C组和D组。表明本发明的猫眼部护理液能有效辅助治疗猫眼部炎症，帮助缓解猫眼部充血、肿胀和分泌物增多，促进猫眼部疾病的治愈。
需要说明的是，以上所述仅为本发明的优选实施例而已，并不用于限制本发明，尽管参照上述实施例对本发明进行了详细的说明，对于本领域技术人员来说，其依然可以对上述各实施例所记载的技术方案进行修改，或者对其中部分技术特征进行等同替换。凡在本发明的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本发明的保护范围之内。
Claims (5)
1.一种猫眼部护理液，其特征在于，制成每100体积份的所述猫眼部护理液的有效成分的原料，包括：复合氨基酸2.5-3.2重量份、硼酸1.6-2.3重量份和洋甘菊提取液2.5-3.2体积份；
其中，重量份数与体积份数的比例关系为g：mL。
2.根据权利要求1所述的猫眼部护理液，其特征在于，所述复合氨基酸由谷氨酸、缬氨酸和亮氨酸混合而成。
3.根据权利要求2所述的猫眼部护理液，其特征在于，所述复合氨基酸由1.4-2.5重量份的谷氨酸、0.3-1.3重量份的缬氨酸和0.8-2.1重量份的亮氨酸混合而成。
4.权利要求1-3中任一项所述的猫眼部护理液的一种制备方法，其特征在于，它是取所有原料加至注射用水中，溶解混匀，无菌过滤，即得所述猫眼部护理液。
5.权利要求1-3中任一项所述的猫眼部护理液的一种应用，其特征在于，所述猫眼部护理液用于猫眼部护理，预防及辅助治疗猫眼部充血、肿胀、分泌物多。
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995030414A1 (en) * | 1994-05-06 | 1995-11-16 | Smith Francis X | An improved ocular care solution |
| CN109549985A (zh) * | 2018-12-17 | 2019-04-02 | 广州市中科慢性病医学研究院 | 一种透过皮肤吸收快速修复视力的小分子肽护眼液 |
| CN109908199A (zh) * | 2019-04-24 | 2019-06-21 | 嘉兴力山明朗生物医药科技有限公司 | 一种洋甘菊洗眼液 |
| CN115054676A (zh) * | 2022-02-22 | 2022-09-16 | 上海弗艾柏生物科技有限公司 | 宠物洗眼液及其应用 |
-
2020
- 2020-10-27 CN CN202011162743.0A patent/CN114470022B/zh active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995030414A1 (en) * | 1994-05-06 | 1995-11-16 | Smith Francis X | An improved ocular care solution |
| CN109549985A (zh) * | 2018-12-17 | 2019-04-02 | 广州市中科慢性病医学研究院 | 一种透过皮肤吸收快速修复视力的小分子肽护眼液 |
| CN109908199A (zh) * | 2019-04-24 | 2019-06-21 | 嘉兴力山明朗生物医药科技有限公司 | 一种洋甘菊洗眼液 |
| CN115054676A (zh) * | 2022-02-22 | 2022-09-16 | 上海弗艾柏生物科技有限公司 | 宠物洗眼液及其应用 |
Non-Patent Citations (1)
| Title |
|---|
| 刘朗等: "擦亮猫猫的"心灵之窗"", 《宠物世界(猫迷)》 * |
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