CN114456910A

CN114456910A - Automatic change nucleic acid sample detection sampler

Info

Publication number: CN114456910A
Application number: CN202210296217.6A
Authority: CN
Inventors: 李巧玲; 薛海阔
Original assignee: Henan Childrens Hospital Zhengzhou Childrens Hospital
Current assignee: Henan Childrens Hospital Zhengzhou Childrens Hospital
Priority date: 2022-03-24
Filing date: 2022-03-24
Publication date: 2022-05-10

Abstract

The invention discloses an automatic nucleic acid sample detection sampler, which relates to the technical field of nucleic acid sample detection samplers, and is characterized in that an electric support rotary drum, a lifting lantern ring, a telescopic electric pole and a positioning corner motor are arranged to control the multidirectional and multi-increment directional movement of a self-uncapping assembly and a pressing sampling structure, and the multidirectional and multi-increment directional movement of the self-uncapping assembly and the pressing sampling structure is controlled, so that the automatic and intelligent cap picking, sampling and sample making processes are realized, the labor intensity of medical workers is reduced, the physical health of the medical workers is protected, the working efficiency is improved, the labor cost is saved, the subsequent observation and detection progress is improved, and the problems of low efficiency and high labor intensity caused by the traditional method of manually picking, sampling and making a large number of samples are solved.

Description

Automatic change nucleic acid sample detection sampler

Technical Field

The invention relates to the technical field of nucleic acid sample detection samplers, in particular to an automatic nucleic acid sample detection sampler.

Background

The existing new crown nucleic acid detection is socially normalized, the demand of the new crown nucleic acid detection on personnel is greatly increased, the speed of extracting the new crown nucleic acid is remarkably improved due to the clinical popularization of an automatic nucleic acid extractor, the existing method includes the steps of manually picking the tube cover of a sample tube, sampling the sample in the sample tube and preparing the sample in the sample tube, and when a large amount of detection is needed, the problems of low efficiency and high labor intensity are caused

In view of the above technical drawbacks, a solution is proposed.

Disclosure of Invention

The invention aims to: through setting up electronic support rotary drum, the lift lantern ring, flexible pole and location corner motor control are from taking off the cap subassembly and pressing down the diversified directional removal that adds the degree of sample structure, through control from taking off the cap subassembly and pressing down the diversified directional removal that adds the degree of sample structure, realize automatic, intelligent pluck the lid, sample and system appearance process, medical staff's intensity of labour has been reduced, protection medical staff's is healthy, and the work efficiency is enhanced, the human cost is saved, the progress of follow-up observation detection is improved.

In order to achieve the purpose, the invention adopts the following technical scheme:

an automatic nucleic acid sample detection sampler comprises a bottom plate, wherein the top surface of the bottom plate is provided with an electric support rotary drum and a sample placing tray, the outer end of the electric support rotary drum is slidably connected with two lifting lantern rings, the lifting lantern rings are arranged at equal intervals, one side of each lifting lantern ring is fixedly arranged on a telescopic electric pole, one end of each telescopic electric pole, far away from the corresponding lifting lantern ring, is provided with a positioning corner motor, the output shafts of the two positioning corner motors are respectively provided with a self-uncapping component and a pressing sampling structure, the self-uncapping component and the pressing sampling structure are arranged at included angles and are in clearance fit with each other, the sample placing tray is provided with a plurality of sample placers, sample tubes are movably arranged in the sample placers and are in sliding clamping connection with the inner walls of the sample placers, the top surface of the bottom plate is provided with three placing grooves, the utility model discloses a sampling device, including standing groove, suction head recovery tray, sample liquid observation tray, suction head, sample liquid, and place the tray, the suction head is placed the tray and is offered the suction head and place the recess, the suction head is placed and is placed the sampling straw in the recess, the top of sample pipe with from taking off cap subassembly swing joint, the top of sampling straw with press the sample structure activity card.

Further, the inner symmetry of the lift lantern ring is equipped with and extends smooth protruding, it slides the inner wall that runs through electronic support rotary drum to extend to its inside and fixed joint has fixed snap ring to extend smooth protruding one end of keeping away from the lift lantern ring, the inner of fixed snap ring is the internal thread form, electronic lead screw has been cup jointed to fixed snap ring screw thread, electronic lead screw rotates and locates in the electronic support rotary drum, and on electronic support rotary drum axis was located to electronic lead screw, electronic support rotary drum has been seted up the adaptation and has been extended smooth protruding gliding first spacing slide, extend smooth protruding and locate in the first spacing slide.

Furthermore, the self-uncapping component comprises a power box, the top center of the power box is fixedly connected with an output shaft of a positioning corner motor, an electric rotating rod, a driving gear, a steering gear, a transmission gear, a first transmission rotating rod and a second transmission rotating rod are arranged in the power box in a rotating mode, the driving gear is fixedly sleeved at the outer end of the electric rotating rod, the steering gear is fixedly sleeved at the outer end of the first transmission rotating rod, the first transmission rotating rod is rotatably arranged in the power box, the steering gear is symmetrically meshed with the driving gear, the transmission gear and the second transmission rotating rod are symmetrically arranged in two numbers, the transmission gear is fixedly sleeved at the outer end of the second transmission rotating rod, the two transmission gears are respectively meshed with the opposite sides of the steering gear and the driving gear, one end of the second transmission rotating rod is rotatably penetrates through the bottom wall of the power box and extends to the outside of the power box, and is fixedly connected with a clamping rotating sleeve, the joint is changeed the cover and is equipped with and takes off the cap and slide protruding, take off the cap and slide protruding pipe cap slip joint with the sample pipe, take off the cap and slide protruding axis that uses the joint to change the cover and be the dot and according to annular array distribution, the fixed cover of bottom portion that the cover was changeed in the joint is equipped with elastic clamping sleeve, elastic clamping sleeve is equipped with butt portion, butt portion and the pipe cap bottom activity butt of sample pipe.

Furthermore, the pressing sampling structure comprises a gas distribution box, the top end of the gas distribution box is fixedly connected with an output shaft of a positioning corner motor, an electric air rod and a sliding plate are arranged in the gas distribution box, the outer end of the sliding plate is abutted against the inner wall of the gas distribution box, the top end of the electric air rod is fixedly connected with the sliding plate, the electric air rod is installed at the central axis of the gas distribution box, a connecting cylinder sleeve is fixedly arranged at the bottom end of the gas distribution box, an air outlet hole is formed in the bottom wall of the gas distribution box, the connecting cylinder sleeve is communicated and connected with the gas distribution box through the air outlet hole, a sliding block and a connecting sliding rod are arranged in the connecting cylinder sleeve, the sliding block is fixedly connected with the top end of the connecting sliding rod, the outer end of the sliding block is abutted against the inner wall of the connecting cylinder sleeve, a limiting cylinder sleeve is fixedly arranged at the bottom end of the cylinder sleeve, the limiting cylinder sleeve corresponds to the number of the clamping rotating sleeve, and a locking assembly is arranged in the limiting cylinder sleeve, the connecting sliding rod penetrates through the outer wall of the limiting cylinder sleeve in a sliding mode, extends into the limiting cylinder sleeve, and is in transmission connection with the extrusion locking assembly.

Furthermore, the extrusion locking assembly comprises an extrusion block, the extrusion block is slidably arranged in a limiting cylinder sleeve, the top end of the extrusion block is fixedly connected with the bottom end of a connecting slide rod, the outer end of the extrusion block is symmetrically provided with hinged convex strips, the hinged convex strips penetrate through the inner wall of the limiting cylinder sleeve and extend to the outside of the limiting cylinder sleeve and are hinged with v-shaped hinged rods, the v-shaped hinged rods are hinged with a support rod and a return block, one end of the support rod is arranged in the middle of the v-shaped hinged rods, the other end of the support rod is fixedly connected with the outer wall of the limiting cylinder sleeve, the return block is arranged at the end part of the v-shaped hinged rods, a locking slide rod is fixedly arranged on one side of the return block, a return spring is sleeved at the outer end of the locking slide rod, the two ends of the return spring are respectively fixedly connected with the return block and the limiting cylinder sleeve, one end, far away from the return block, of the locking slide rod penetrates through the outer end of the limiting cylinder sleeve and extends to the inside of the limiting cylinder sleeve and is fixedly provided with a locking arc part, the locking arc part is movably clamped with the outer end of the top of the sampling straw, and the extrusion block is movably abutted against the top end of the sampling straw.

Furthermore, the second limiting slide way matched with the hinged raised lines and sliding is arranged on the limiting cylinder sleeve, the hinged raised lines penetrate through the second limiting slide way in a sliding mode, and the side faces of the hinged raised lines are abutted to the inner wall of the second limiting slide way.

Further, the sampling straw comprises joint ring, sampling shell and extrusion vesicle, the top of sampling shell is located to the fixed cover of joint ring, the extrusion vesicle is installed on the joint ring, and the extrusion vesicle and the sampling shell through connection, the side opening has been seted up to the bottom outside of sampling shell, the sampling shell link up with the outside through the side opening, the joint groove has been seted up to the outer end of joint ring, locking arc portion and joint groove activity joint, and the extrusion vesicle and extrusion piece activity butt.

In summary, due to the adoption of the technical scheme, the invention has the beneficial effects that:

according to the invention, the electric support rotary drum, the lifting lantern ring, the telescopic electric pole and the positioning corner motor are arranged to control the directional movement of the self-uncapping assembly and the pressing sampling structure in multiple directions and multiple degrees, and the directional movement of the self-uncapping assembly and the pressing sampling structure in multiple directions and multiple degrees is controlled, so that the automatic and intelligent cap picking, sampling and sample making processes are realized, the labor intensity of medical workers is reduced, the health of the medical workers is protected, the working efficiency is enhanced, the labor cost is saved, the subsequent observation and detection progress is improved, and the problems of lower efficiency and higher labor intensity caused by the traditional manual cap picking, sampling and sample making of a large number of samples are solved.

Drawings

FIG. 1 shows a perspective view of the present invention;

FIG. 2 shows an enlarged cross-sectional view at the electrically-powered support drum;

FIG. 3 shows a schematic structural view of a self-uncapping assembly;

FIG. 4 shows a partial enlarged view at A of FIG. 3;

FIG. 5 shows a schematic of a push sampling structure;

FIG. 6 shows a partial enlarged view at B of FIG. 5;

FIG. 7 shows a close-up view at the return spring;

FIG. 8 shows a perspective view of a sampling pipette;

illustration of the drawings: 1. a base plate; 2. electrically supporting the drum; 3. a lifting lantern ring; 4. a telescopic electric pole; 5. positioning a corner motor; 6. a self-uncapping assembly; 7. pressing the sampling structure; 8. a specimen holding tray; 9. a sucker placing tray; 10. a sucker recovery tray; 11. a standard liquid observation tray; 12. standard solution observation paper; 13. a groove for nucleic acid to be detected; 301. extending the sliding protrusion; 302. a first limiting slideway; 303. an electric screw rod; 304. fixing the snap ring; 601. a power box; 602. an electric rotating rod; 603. a driving gear; 604. a steering gear; 605. a transmission gear; 606. a first transmission rotary rod; 607. a second transmission rotating rod; 608. clamping the rotating sleeve; 609. taking off the cap and sliding the convex part; 610. an elastic card sleeve; 611. an abutting portion; 701. a gas distribution box; 702. an electric air rod; 703. a slide plate; 704. an air outlet; 705. connecting the cylinder sleeve; 706. a slider; 707. connecting a sliding rod; 708. a limiting cylinder sleeve; 709. extruding the block; 710. hinging the convex strips; 711. a v-shaped hinge rod; 712. a support bar; 713. a bit returning block; 714. a return spring; 715. locking the sliding rod; 716. a locking arc part; 717. a second limiting slideway; 801. a specimen placer; 802. a sample tube; 901. the suction head placing groove; 902. a sampling straw; 903. a snap ring; 904. sampling a shell; 905. squeezing the vesicles; 906. a side hole; 907. a clamping groove.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1:

as shown in FIGS. 1-8, an automatic nucleic acid sample detection sampler comprises a bottom plate 1, wherein the top surface of the bottom plate 1 is provided with an electric support drum 2 and a sample placing tray 8, the outer end of the electric support drum 2 is slidably clamped with a lifting lantern ring 3, the lifting lantern ring 3 is provided with two lifting lantern rings at equal intervals, one side of the lifting lantern ring 3 is fixedly installed on a telescopic electric pole 4, one end of the telescopic electric pole 4, which is far away from the lifting lantern ring 3, is provided with a positioning corner motor 5, the output shafts of the two positioning corner motors 5 are respectively provided with a self-uncapping assembly 6 and a pressing sampling structure 7, the self-uncapping assembly 6 and the pressing sampling structure 7 are arranged at an included angle, and an extrusion locking assembly is in clearance fit with the pressing sampling structure 7, the sample placing tray 8 is provided with a plurality of sample placers 801, a sample tube 802 is movably arranged in the sample placers 801, the sample tube 802 is slidably clamped with the inner wall of the sample placers 801, the sample placer 801 is used for placing a sample tube 802 and preventing the sample tube 802 from rotating, a pressure sensor is arranged in the sample placer 801 and used for sensing the position and the placing state of the sample tube 802, three placing grooves are arranged on the top surface of the bottom plate 1, a suction head placing tray 9, a suction head recycling tray 10 and a sample liquid observing tray 11 are respectively and movably arranged in the placing grooves, sample liquid observing paper 12 is arranged in the sample liquid observing tray 11, a plurality of grooves 13 for nucleic acid detection are arranged on the sample liquid observing paper 12, a suction head placing groove 901 is arranged on the suction head placing tray 9, a sampling suction pipe 902 is arranged in the suction head placing groove 901, the top of the sample tube 802 is movably connected with a self-uncapping assembly 6, the top of the sampling suction pipe 902 is movably clamped with a pressing sampling structure 7, the sample placing tray 8, the suction head placing tray 9, the recycling tray 10 and the sample liquid observing tray 11 can be movably taken and replaced, the detection is simpler and more reusable;

the electric support rotating drum 2 is used for driving the telescopic electric pole 4 to rotate and the positioning corner motor 5 to rotate, so as to drive the self-uncapping assembly 6 and the pressing sampling structure 7 to rotate in a fan shape right above the bottom plate 1, the telescopic electric pole 4 is telescopic to drive the self-uncapping assembly 6 and the pressing sampling structure 7 to stretch, so as to enable the self-uncapping assembly 6 and the pressing sampling structure 7 to move linearly right above the bottom plate 1, so as to control the self-uncapping assembly 6 and the pressing sampling structure 7 to move in each area right above the bottom plate 1 and ensure the moving area of the self-uncapping assembly, and the positioning corner motor 5 is matched to drive the self-uncapping assembly 6 and the pressing sampling structure 7 to rotate, so as to enable the self-uncapping assembly 6 or the pressing sampling structure 7 to be positioned right above the suction head placing tray 9, the suction head recycling tray 10 or the standard liquid observation tray 11 in parallel and vertical mode, so as to ensure the normal operation of the subsequent work, so as to enable the self-uncapping assembly 6 and the pressing sampling structure 7 to be parallel or vertical to be right above the sampling suction pipe 902 and the standard pipe 802, so as to achieve the purpose of working in sequence or in multiple batches;

the inner symmetry of the lift lantern ring 3 is equipped with the smooth protruding 301 of extension, the one end that the smooth protruding 301 of extension kept away from the lift lantern ring 3 slides and runs through the inner wall that electronic support rotary drum 2 extends to its inside and fixed joint has fixed snap ring 304, the inner of fixed snap ring 304 is the internal thread form, fixed snap ring 304 screw thread cover has been connected with electronic lead screw 303, electronic lead screw 303 rotates to be located in electronic support rotary drum 2, and electronic lead screw 303 locates on the electronic support rotary drum 2 axis, electronic support rotary drum 2 has been seted up the adaptation and has been extended the gliding first spacing slide 302 of smooth protruding 301, extend smooth protruding 301 and locate in the first spacing slide 302, control electronic lead screw 303 forward rotation back drive with its screw thread cover fixed snap ring 304 of going up and down, fixed snap ring 304 after going up and down drive rather than the smooth protruding 301 of extension of blocking down the ration slide 302, extend smooth protruding 301 along first spacing slide 302 down the ration slide after the ration slide drive rather than fixed lift lantern ring 3 along the downward ration slide of electronic support rotary drum 2 slide ring 3 After the lifting lantern ring 3 slides downwards quantitatively, the lifting lantern ring moves downwards quantitatively through a telescopic electric pole 4 fixed with the lifting lantern ring, the telescopic electric pole 4 moves downwards quantitatively and then drives a positioning corner motor 5 fixed with the telescopic electric pole to move downwards quantitatively, two positioning corner motors 5 move downwards quantitatively and then drive a self-uncapping assembly 6 and a pressing sampling structure 7 which are respectively arranged on the positioning corner motors to move downwards quantitatively, and the self-uncapping assembly 6 and the pressing sampling structure 7 are controlled to move upwards quantitatively by controlling the reverse rotation of an electric screw rod 303, so that the sampling is guaranteed to carry out automatic work according to standards;

the self-uncapping component 6 comprises a power box 601, the center of the top end of the power box 601 is fixedly connected with an output shaft of a positioning corner motor 5, an electric rotating rod 602, a driving gear 603, a steering gear 604, a transmission gear 605, a first transmission rotating rod 606 and a second transmission rotating rod 607 are rotationally arranged in the power box 601, the driving gear 603 is fixedly sleeved at the outer end of the electric rotating rod 602, the steering gear 604 is fixedly sleeved at the outer end of the first transmission rotating rod 606, the steering gear 604 is symmetrically engaged with the driving gear 603, two transmission gears 605 and two second transmission rotating rods 607 are symmetrically arranged, the transmission gear 605 is fixedly sleeved at the outer end of the second transmission rotating rod 607, the two transmission gears 605 are respectively meshed at the opposite sides of the steering gear 604 and the driving gear 603, one end of the second transmission rotating rod 607 rotatably penetrates through the bottom wall of the power box 601 to extend to the outside and is fixedly connected with a clamping rotating sleeve 608, the clamping rotating sleeve 608 is provided with an uncapping sliding protrusion 609, the uncapping sliding protrusion 609 is in sliding clamping connection with the tube cover of the sample tube 802, the uncapping sliding protrusion 609 takes the central axis of the clamping rotary sleeve 608 as a circular point and is distributed according to an annular array, an elastic clamping sleeve 610 is fixedly sleeved at the bottom end part of the clamping rotary sleeve 608, the elastic clamping sleeve 610 is provided with a butting part 611, and the butting part 611 is movably butted with the bottom end of the tube cover of the sample tube 802;

when the clamping rotary sleeve 608 is sleeved at the outer end of the tube cover of the sample tube 802, the electric rotary rod 602 which is rotatably arranged in the power box 601 is controlled to rotate forward for a certain number of turns and drive the driving gear 603 fixed with the driving gear 603, the driving gear 603 drives the steering gear 604 which is symmetrically meshed with the driving gear 603 to rotate forward, the steering gear 604 and the driving gear 603 drive the two transmission gears 605 which are meshed with the opposite sides of the steering gear to rotate forward after rotating forward, the steering gear 604 is fixedly sleeved at the outer end of the first transmission rotary rod 606, the first transmission rotary rod 606 is rotatably arranged in the power box 601 to ensure the stability of the steering gear 604, the transmission gear 605 drives the second transmission rotary rod 607 which is fixedly sleeved with the transmission gear to rotate forward after rotating forward, the second transmission rotary rod 607 drives the clamping rotary sleeve 608 fixed with the second transmission rotary rod to rotate forward, the clamping rotary sleeve 608 drives the cap-off sliding protrusion 609 which is integrated with the clamping rotary sleeve to rotate forward, at the moment, the uncapping sliding protrusion 609 is clamped in a tube cover sliding groove of the sample tube 802;

the clamping rotary sleeve 608 rotates forwards to abut against the side wall of the pipe cover sliding chute of the sample pipe 802, the rotary force is transmitted to the pipe cover of the sample pipe 802, the pipe cover of the sample pipe 802 is separated from the threaded connection state, at the moment, the self-releasing cap assembly 6 moves upwards and quantitatively, the elastic clamping sleeve 610 fixedly arranged at the bottom of the clamping rotary sleeve 608 props up upwards from the bottom end of the pipe cover of the sample pipe 802, so that the pipe cover of the sample pipe 802 is automatically taken out, after sampling and sample preparation are completed, the self-releasing cap assembly 6 returns to the position and moves downwards and quantitatively, the pipe cover of the sample pipe 802 is sleeved at the pipe opening of the sample pipe 802 again, then the clamping rotary sleeve 608 rotates reversely for a fixed number of turns through controlling the electric rotary rod 602 and is transmitted through the steps, so that the clamping rotary sleeve 608 rotates reversely to push the pipe cover of the sample pipe 802 to recover the threaded connection state, then the self-releasing cap assembly 6 is controlled to move upwards and quantitatively, so that the releasing cap sliding protrusion 609 slides out along the sliding chute of the pipe cover of the sample pipe 802, the abutting part 611 is not abutted with the end part of the tube cover of the sample tube 802, and the extrusion force of the inner ring side of the sample placer 801 prevents the sample tube 802 from running out, so that the automatic cover removing and covering process is realized without manual operation, and the operation is simple, convenient and quick;

the pressing sampling structure 7 comprises a gas distribution box 701, the top end of the gas distribution box 701 is fixedly connected with an output shaft of a positioning corner motor 5, an electric air rod 702 and a sliding plate 703 are arranged in the gas distribution box 701, the outer end of the sliding plate 703 is abutted against the inner wall of the gas distribution box 701, the top end of the electric air rod 702 is fixedly connected with the sliding plate 703, the electric air rod 702 is arranged at the central axis of the gas distribution box 701, a connecting cylinder sleeve 705 is fixedly arranged at the bottom end of the gas distribution box 701, an air outlet hole 704 is arranged on the bottom wall of the gas distribution box 701, the connecting cylinder sleeve 705 is in through connection with the gas distribution box 701 through the air outlet hole 704, a sliding block 706 and a connecting sliding rod 707 are arranged in the connecting cylinder sleeve 705, the sliding block 706 is fixedly connected with the top end of the connecting sliding rod 707, the outer end of the sliding block 706 is in sliding abutting connection with the inner wall of the connecting cylinder sleeve 705, a limiting cylinder sleeve 708 is fixedly arranged at the bottom end of the connecting cylinder sleeve 705, the number of the limiting cylinder sleeve 708 is equal to that of the clamping rotating sleeves 608, and the connecting sliding rod 707 penetrates through the outer wall of the limiting cylinder sleeve 708 in a sliding mode and extends into the limiting cylinder sleeve 708;

an extrusion block 709 is arranged in the limiting cylinder sleeve 708 in a sliding mode, the top end of the extrusion block 709 is fixedly connected with the bottom end of a connecting sliding rod 707, the outer end of the extrusion block 709 is symmetrically provided with a hinge convex strip 710, the hinge convex strip 710 penetrates through the inner wall of the limiting cylinder sleeve 708 and extends to the outside of the limiting cylinder sleeve 708 and is hinged with a v-shaped hinge rod 711, the v-shaped hinge rod 711 is hinged with a support rod 712 and a return block 713, one end of the support rod 712 is arranged in the middle of the v-shaped hinge rod 711, the other end of the support rod 712 is fixedly connected with the outer wall of the limiting cylinder sleeve 708, the return block 713 is arranged at the end of the v-shaped hinge rod 711, a locking sliding rod 715 is fixedly arranged on one side of the return block 713, the outer end of the locking sliding rod 715 is sleeved with a return spring 714, the two ends of the return spring 714 are respectively fixedly connected with the return block 713 and the limiting cylinder sleeve 708, one end of the locking sliding rod 715 far away from the return block 713 penetrates through the outer end of the limiting cylinder sleeve 708 and extends to the inside of the limiting cylinder sleeve 708 and is fixedly provided with a locking arc 716, the locking arc portion 716 is movably clamped with the outer end of the top of the sampling straw 902, the extrusion block 709 is movably abutted with the top end of the sampling straw 902, the limiting cylinder sleeve 708 is provided with a second limiting slide 717 matched with the hinge convex strip 710 to slide, the hinge convex strip 710 slidably penetrates through the second limiting slide 717, and the side surface of the hinge convex strip 710 is abutted with the inner wall of the second limiting slide 717;

the sampling straw 902 is composed of a clamping ring 903, a sampling shell 904 and an extrusion vesicle 905, the clamping ring 903 is fixedly sleeved at the top end of the sampling shell 904, the extrusion vesicle 905 is installed on the clamping ring 903, the extrusion vesicle 905 is communicated with the sampling shell 904, a side hole 906 is formed in the outer part of the bottom end of the sampling shell 904, the sampling shell 904 is communicated with the outside through the side hole 906, a clamping groove 907 is formed in the outer end of the clamping ring 903, a locking arc 716 is movably clamped with the clamping groove 907, and the extrusion vesicle 905 is movably abutted with an extrusion block 709;

the concrete process of sampling and sample preparation, after the tube cover of the sample tube 802 is taken out, indirectly controlling the pressing and sampling structure 7 to move right above the sampling suction tube 902, then controlling the pressing and sampling structure 7 to move downwards and quantitatively, so that the top end of the sampling suction tube 902 is inserted into the limit cylinder sleeve 708, at the moment, the outer end arc part of the top of the clamping ring 903 of the sampling shell 904 is abutted to the locking arc part 716 and gradually drives the locking slide rod 715 integrated with the locking arc part to slide out of the limit cylinder sleeve 708, the locking slide rod 715 slides out of the limit cylinder sleeve 708 and drives the return block 713 fixed with the locking slide rod 713 to move outwards, the return block 713 drives the return spring 714 fixed with the return block 713 to open after moving outwards, the reverse acting force of the return spring 714 drives the locking arc part 716 to be always abutted to the outer end of the clamping ring 903 until the locking arc part 716 is positioned in the clamping groove 907 of the clamping ring 903, and ensures that the locking arc part 716 is abutted to the inner wall of the clamping groove 907 under the return force of the return spring 714, the top of the locking arc 716 abuts against the top inner wall of the clamping groove 907, so that the sampling straw 902 is locked;

after the sampling straw 902 is locked, the sampling structure 7 is controlled to move to drive the sampling straw 902 on the sampling structure to be inserted from the pipe orifice of the sample pipe 802, the bottom end of the sampling straw 902 abuts against the bottom wall of the sample pipe 802, the electric air rod 702 is started to work and drives the sliding plate 703 fixed with the electric air rod to move downwards along the inner wall of the air distribution box 701, the sliding plate 703 moves downwards along the inner wall of the air distribution box 701 to extrude the air in the air distribution box 701, the air in the air distribution box 701 enters the cylinder sleeve 705 through the air outlet holes 704, the air enters the connecting cylinder sleeve 705 to be accumulated and extrude the sliding block 706, the sliding block 706 slides downwards along the inner wall of the connecting cylinder sleeve 705, the sliding block 706 drives the connecting sliding rod 707 fixed with the sliding block to slide downwards after sliding downwards, the connecting sliding rod 707 drives the extrusion block 709 fixed with the sliding block to slide downwards, the extrusion block 709 slides downwards to abut against the extrusion vesicle 905, the extruded vesicle 905 contracts and drives local gas in the sampling shell 904 to come out, when the extruded block 709 slides to a preset distance, the electric air rod 702 is controlled to drive the sliding plate 703 to slide upwards along the gas distribution box 701, the extruded vesicle 905 is restored after the transmission of the components, so that a certain amount of negative pressure suction force is generated in the sampling shell 904, and then the sampling shell 904 transmits the negative pressure suction force through the side hole 906 so as to suck liquid to be detected in the sample tube 802;

after the liquid to be detected is sucked, the pressing and sampling structure 7 is controlled to move to the standard liquid observation tray 11, the sampling straw 902 is enabled to be abutted against the bottom wall of the groove 13 to be detected for nucleic acid, then the squeezing vesicle 905 is controlled to shrink, the liquid to be detected in the squeezing sampling shell 904 after the squeezing vesicle 905 shrinks is enabled to be sprayed into the groove 13 to be detected for nucleic acid from the side hole 906, the sample preparation process is completed, and the part is reset to enable the sampling straw 902 to be clamped again; a solution or test paper or a glass slide for detecting the liquid to be detected is arranged in the groove 13 to be detected for the nucleic acid, and is used for the subsequent automatic high-density detection of the nucleic acid;

after the sample preparation is finished, the pressing and sampling structure 7 is controlled to move to the position right above the sucker recovery tray 10, and controls the extrusion block 709 to slide downwards, the extrusion block 709 slides downwards to drive the hinge convex strip 710 fixed with the extrusion block to slide downwards, the hinge convex strip 710 slides downwards to drive the v-shaped hinge rod 711 hinged with the extrusion block to deflect outwards at the hinge part with the support rod 712, the v-shaped hinge rod 711 deflects outwards to drive the locking slide rod 715 fixed with the extrusion block to move outwards, the locking slide rod 715 moves outwards to drive the locking arc 716 integrated with the extrusion block to come out of the clamping groove 907, thereby disengaging from the snap fit with the snap fit groove 907, while the expression block 709 pushes downward from the top of the sampling pipette 902 after sliding downward, thereby enabling the sampling pipettes 902 to disengage from the press sampling structure 7 and fall into the tip recovery tray 10, thereby facilitating uniform recovery or disposal of the sampling pipettes 902;

the working method of the invention is as follows:

firstly, placing a plurality of sample tubes 802 in a sample placer 801, placing a plurality of sampling straws 902 in a sucker placing groove 901, then placing the invention in a biosafety cabinet, a glass sealing cabinet or an automatic observation cabinet, amplifying the position of a groove 13 to be detected of the nucleic acid of a sample liquid observation paper 12, facilitating the observation of a worker, and then controlling the operation of parts through a mobile phone or an external controller and the Internet;

step two, indirectly controlling the self-uncapping component 6 to slide and sleeve into the top of the sample tube 802, enabling the top of the sample tube 802 to be abutted against the top surface of the self-uncapping component 6, then controlling the self-uncapping component 6 to pick off a tube cover of the sample tube 802, indirectly controlling the pressing sampling structure 7 to move and enable the pressing sampling structure 7 to clamp and fix the top end part of the sampling suction tube 902, then controlling the sampling suction tube 902 to move and insert into the sample tube 802, enabling the bottom end of the sampling suction tube 902 to be abutted against the bottom wall of the sample tube 802, then extruding and returning the top end of the sampling suction tube 902 to deform and automatically suck liquid to be detected in the sample tube 802;

thirdly, after the sampling pipette 902 sucks the liquid to be detected, the sampling structure moves to clamp and fix the sampling pipette 902 again and drive the sampling pipette 902 to the groove 13 to be detected for nucleic acid, then the bottom end of the sampling pipette 902 is abutted to the bottom wall of the groove 13 to be detected for nucleic acid, the liquid to be detected in the sampling pipette 902 enters the groove 13 to be detected for nucleic acid by pressing, then the sampling pipette 902 is locked again and driven to move to the suction head recovery tray 10, the sampling pipette 902 is separated from the locked state by controlling the pressing of the sampling structure 7, so that the sampling pipette 902 falls into the suction head recovery tray 10, then the self-uncapping component 6 is controlled to reset the tube cover of the picked sample tube 802 again, then the tube cover of the sample tube 802 is driven to rotate reversely, the tube cover of the sample tube 802 is screwed again, the pollution rate is reduced, and the reutilization rate is increased;

step four, after the sampling suction pipe 902 falls into the suction head recovery tray 10, repeating the steps of the step two and the step three, sampling and sample preparation of all the sample tubes 802, observing the sample preparation when all the sampling, sampling and sample preparation are completed, detecting whether the disease is caused, and carrying out sealed storage or sterile destruction on the sample preparation, wherein the sample tubes 802 and the sample preparation are in one-to-one correspondence; sterilizing and inactivating other waste materials and then uniformly destroying the waste materials;

according to the invention, the electric support rotary drum 2, the lifting lantern ring 3, the telescopic electric pole 4 and the positioning corner motor 5 are arranged to control the multi-direction and multi-increment directional movement of the self-uncapping assembly 6 and the pressing sampling structure 7, and the multi-direction and multi-increment directional movement of the self-uncapping assembly 6 and the pressing sampling structure 7 is controlled, so that the automatic and intelligent cap picking, sampling and sample making processes are realized, the labor intensity of medical workers is reduced, the body health of the medical workers is protected, the working efficiency is enhanced, the labor cost is saved, the progress of subsequent observation and detection is improved, and the problems of lower efficiency and higher labor intensity caused by the traditional manual cap picking, sampling and sample making of a large number of samples are solved.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims

1. An automatic nucleic acid sample detection sampler comprises a bottom plate (1) and is characterized in that an electric support rotary drum (2) and a sample placing tray (8) are arranged on the top surface of the bottom plate (1), a lifting sleeve ring (3) is connected to the outer end of the electric support rotary drum (2) in a sliding manner, two lifting sleeve rings (3) are arranged at equal intervals, one side of each lifting sleeve ring (3) is fixedly mounted on a telescopic electric pole (4), a positioning corner motor (5) is arranged at one end, away from the lifting sleeve ring (3), of each telescopic electric pole (4), a self-uncapping assembly (6) and a pressing sampling structure (7) are respectively mounted on an output shaft of each positioning corner motor (5), the self-uncapping assembly (6) and the pressing sampling structure (7) are arranged at included angles, a locking assembly is pressed and the pressing sampling structure (7) is in clearance fit, the sample placing tray (8) is provided with a plurality of sample placers (801), sample placer (801) internalization is equipped with sample pipe (802), the inner wall slip joint of sample pipe (802) and sample placer (801), three standing groove has been seted up to the top surface of bottom plate (1), the activity is equipped with the suction head respectively in the standing groove and places tray (9), suction head recovery tray (10) and mark liquid observation tray (11), it observes paper (12) to be equipped with mark liquid in observation tray (11), mark liquid observation paper (12) are equipped with a plurality of nucleic acid and wait to examine recess (13), suction head placement tray (9) have been seted up suction head placement groove (901), sampling straw (902) have been placed in suction head placement groove (901), the top of sample pipe (802) and from taking off cap subassembly (6) swing joint, the top of sampling straw (902) and press sampling structure (7) activity card.

2. An automated nucleic acid sample detection sampler according to claim 1, the inner end of the lifting lantern ring (3) is symmetrically provided with extending sliding protrusions (301), one end of each extending sliding protrusion (301), far away from the lifting lantern ring (3), penetrates through the inner wall of the electric support rotary drum (2) in a sliding mode, extends into the electric support rotary drum and is fixedly clamped with a fixing clamping ring (304), the inner end of the fixed snap ring (304) is in an internal thread shape, the fixed snap ring (304) is sleeved with an electric screw rod (303) in a threaded manner, the electric screw rod (303) is rotatably arranged in the electric supporting rotary drum (2), and electric screw rod (303) are arranged on the central axis of electric support rotary drum (2), electric support rotary drum (2) is provided with a first limiting slide way (302) which is matched with and extends sliding protrusion (301), and the extending sliding protrusion (301) is arranged in the first limiting slide way (302).

3. The automatic nucleic acid sample detection sampler according to claim 1, wherein the self-uncapping assembly (6) comprises a power box (601), the center of the top end of the power box (601) is fixedly connected with the output shaft of the positioning rotation angle motor (5), an electric rotating rod (602), a driving gear (603), a steering gear (604), a transmission gear (605), a first transmission rotating rod (606) and a second transmission rotating rod (607) are rotatably arranged in the power box (601), the driving gear (603) is fixedly sleeved at the outer end of the electric rotating rod (602), the steering gear (604) is fixedly sleeved at the outer end of the first transmission rotating rod (606), the first transmission rotating rod (606) is rotatably arranged in the power box (601), the steering gear (604) is symmetrically engaged with the driving gear (603), two transmission gears (605) and two second transmission rotating rods (607) are symmetrically arranged, and the outer end of a second transmission rotating rod (607) is fixedly sleeved with a transmission gear (605), two transmission gears (605) are respectively meshed with the reverse sides of a steering gear (604) and a driving gear (603), one end of the second transmission rotating rod (607) is rotated to penetrate through the bottom wall of a power box (601) and extend to the outside of the power box and is fixedly connected with a clamping rotating sleeve (608), the clamping rotating sleeve (608) is provided with a cap-removing sliding protrusion (609), the cap-removing sliding protrusion (609) is in sliding clamping connection with a pipe cover of a sample pipe (802), the cap-removing sliding protrusion (609) takes the central axis of the clamping rotating sleeve (608) as a circular point and is distributed according to an annular array, an elastic clamping sleeve (610) is fixedly sleeved at the bottom end part of the clamping rotating sleeve (608), the elastic clamping sleeve (610) is provided with a butting part (611), and the butting part (611) is movably abutted against the bottom end of the pipe cover of the sample pipe (802).

4. The automatic nucleic acid sample detection sampler according to claim 3, wherein the pressing sampling structure (7) comprises a gas distribution box (701), the top end of the gas distribution box (701) is fixedly connected with the output shaft of the positioning rotation angle motor (5), an electric air rod (702) and a sliding plate (703) are arranged in the gas distribution box (701), the outer end of the sliding plate (703) is abutted against the inner wall of the gas distribution box (701), the top end of the electric air rod (702) is fixedly connected with the sliding plate (703), the electric air rod (702) is installed at the central axis of the gas distribution box (701), a connecting cylinder sleeve (705) is fixedly arranged at the bottom end of the gas distribution box (701), an air outlet hole (704) is formed in the bottom wall of the gas distribution box (701), the connecting cylinder sleeve (705) is communicated with the gas distribution box (701) through the air outlet hole (704), a sliding block (706) and a connecting sliding rod (707) are arranged in the connecting cylinder sleeve (705), the top fixed connection of slider (706) and connecting slide bar (707), and the outer end of slider (706) and the inner wall slip butt of connecting cylinder liner (705), the bottom mounting of connecting cylinder liner (705) is equipped with spacing cylinder liner (708), the quantity correspondence of spacing cylinder liner (708) and joint commentaries on classics cover (608) equals, be equipped with extrusion locking Assembly in spacing cylinder liner (708), connecting slide bar (707) slip and run through the outer wall of spacing cylinder liner (708) and extend to its inside and be connected with extrusion locking Assembly transmission.

5. The automatic nucleic acid sample detection sampler according to claim 4, wherein the extrusion locking assembly comprises an extrusion block (709), the extrusion block (709) is slidably disposed in the limiting cylinder sleeve (708), the top end of the extrusion block (709) is fixedly connected with the bottom end of the connecting slide rod (707), the outer end of the extrusion block (709) is symmetrically provided with a hinge convex strip (710), the hinge convex strip (710) extends to the outside of the limiting cylinder sleeve (708) through the inner wall of the limiting cylinder sleeve and is hinged with a v-shaped hinge rod (711), the v-shaped hinge rod (711) is hinged with a support rod (712) and a return block (713), one end of the support rod (712) is disposed in the middle of the v-shaped hinge rod (711), the other end of the support rod (712) is fixedly connected with the outer wall of the limiting cylinder sleeve (708), and the return block (713) is disposed at the end of the v-shaped hinge rod (711), and one side of the return block (713) is fixedly provided with a locking slide rod (715), the outer end of the locking slide rod (715) is sleeved with a return spring (714), two ends of the return spring (714) are respectively fixedly connected with the return block (713) and the limiting cylinder sleeve (708), one end of the locking slide rod (715) far away from the return block (713) slides to penetrate through the outer end of the limiting cylinder sleeve (708) and extends into the interior of the limiting cylinder sleeve (708), a locking arc part (716) is fixedly arranged, the locking arc part (716) is movably clamped with the outer end of the top of the sampling suction pipe (902), and the extrusion block (709) is movably abutted to the top of the sampling suction pipe (902).

6. The automatic nucleic acid sample detection sampler according to claim 5, wherein the limiting cylinder sleeve (708) is provided with a second limiting slide way (717) adapted to the sliding of the hinge convex strip (710), the hinge convex strip (710) slides through the second limiting slide way (717), and the side surface of the hinge convex strip (710) abuts against the inner wall of the second limiting slide way (717).

7. The automatic nucleic acid sample detection sampler of claim 5, wherein the sampling pipette (902) is composed of a clamping ring (903), a sampling shell (904) and an extrusion vesicle (905), the clamping ring (903) is fixedly sleeved at the top end of the sampling shell (904), the extrusion vesicle (905) is installed on the clamping ring (903), the extrusion vesicle (905) is connected with the sampling shell (904) in a penetrating manner, a side hole (906) is formed outside the bottom end of the sampling shell (904), the sampling shell (904) is connected with the outside in a penetrating manner through the side hole (906), a clamping groove (907) is formed in the outer end of the clamping ring (903), the locking arc part (716) is movably clamped with the clamping groove (907), and the extrusion vesicle (905) is movably abutted against the extrusion block (709).