CN114414821A - Reaction cup grabbing device and immunoassay appearance - Google Patents

Reaction cup grabbing device and immunoassay appearance Download PDF

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Publication number
CN114414821A
CN114414821A CN202111600759.XA CN202111600759A CN114414821A CN 114414821 A CN114414821 A CN 114414821A CN 202111600759 A CN202111600759 A CN 202111600759A CN 114414821 A CN114414821 A CN 114414821A
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CN
China
Prior art keywords
reaction cup
photoelectric switch
photoelectric
picking
assembly
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Pending
Application number
CN202111600759.XA
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Chinese (zh)
Inventor
梁俊杰
邓伟锌
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Guangzhou Labsim Biotech Co Ltd
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Guangzhou Labsim Biotech Co Ltd
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Priority to CN202111600759.XA priority Critical patent/CN114414821A/en
Publication of CN114414821A publication Critical patent/CN114414821A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1081Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
    • G01N35/109Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with two horizontal degrees of freedom

Abstract

The invention discloses a reaction cup gripping device and an immunoassay analyzer, which comprise a frame, a pickup mechanism, a sensor assembly and a control terminal, wherein the pickup mechanism is arranged on the frame; the sensor assembly comprises a first photoelectric switch, a second photoelectric switch and a photoelectric barrier sheet; when the reaction cup is not picked up by the picking mechanism, the photoelectric separation blade moves from the first photoelectric switch to the second photoelectric switch, and the control terminal receives a signal of the second photoelectric switch to judge that the reaction cup is not picked up; when the reaction cup is picked up by the picking mechanism, the photoelectric separation blade moves from the first photoelectric switch to a position between the two photoelectric switches to stop, and the control terminal does not receive a signal sent by the second photoelectric switch within preset time, so that the reaction cup is judged to be picked up. The mode of instant feedback through photoelectric signal has faster feedback speed than the mode of traditional detection pressure value change, makes this reaction cup grabbing device pick up the decision-making speed of reaction cup every time and all show and shorten, and then promotes this reaction cup grabbing device's work efficiency.

Description

Reaction cup grabbing device and immunoassay appearance
Technical Field
The invention belongs to the technical field of an immunoassay analyzer, and particularly relates to a reaction cup gripping device and an immunoassay analyzer.
Background
An immunoassay instrument for measuring a bioactive compound with a very low content is an instrument for measuring the content of the bioactive compound based on the principle of antigen-antibody reaction, in which a known antigen or antibody is labeled with a fluorophore, the fluorescent antibody (or antigen) is used as a probe to examine the corresponding antigen (or antibody) in a cell or tissue, the cell or tissue where the fluorescence is located can be seen by a fluorescence microscope to determine the nature and location of the antigen or antibody, and the content is measured by a quantitative technique (such as a flow cytometer).
In an immunoassay analyzer, the cuvettes are usually placed on a carrier platform and are picked up by a gripping device, which picks up the cuvettes from one test site and transports them to another test site. The existing gripping device adopts a sucker structure to adsorb the reaction cup to reduce the occupied space for the miniaturization development of the matched immunity analyzer, and confirms whether to pick up the reaction cup or not by detecting the change of the negative pressure value of the sucker. The mode of detecting the negative pressure value to judge whether the reaction cup is picked up has the problems of slow detection feedback and delayed operation, and influences the working efficiency of the immunoassay analyzer.
In summary, a need exists for a cuvette picking apparatus, which can quickly determine whether a cuvette is picked, reduce the operation delay time, and improve the working efficiency of the gripping apparatus.
Disclosure of Invention
The invention aims to provide a reaction cup grabbing device, which solves the problems of slow detection feedback and delayed operation when judging whether a reaction cup is picked up or not by detecting a negative pressure value.
The invention is realized by the following technical scheme:
a reaction cup gripping device comprises
The device comprises a rack, a driving device and a control device, wherein the rack is provided with a slide rail;
the picking mechanism is slidably mounted on the sliding rail and is used for picking up the reaction cups placed on the bearing platform;
the sensor assembly comprises a first photoelectric switch, a second photoelectric switch and a photoelectric blocking piece, wherein the first photoelectric switch and the second photoelectric switch are both arranged on the rack, the first photoelectric switch is arranged corresponding to the initial position of the picking mechanism, and the distance between the first photoelectric switch and the second photoelectric switch is greater than the distance between the initial position of the picking mechanism and the position of the picking mechanism for picking up the reaction cup and is less than or equal to the distance between the initial position of the picking mechanism and the position of the bottom end of the picking mechanism when the picking mechanism is abutted against the bearing platform; the photoelectric blocking piece is arranged on the picking mechanism, and moves along with the picking mechanism to be respectively matched with the first photoelectric switch and the second photoelectric switch;
the control terminal is respectively in communication connection with the pickup mechanism, the first photoelectric switch and the second photoelectric switch;
when the reaction cup is not picked up by the picking mechanism, the photoelectric separation blade moves from the first photoelectric switch to the second photoelectric switch, and the control terminal receives a signal of the second photoelectric switch to judge that the reaction cup is not picked up;
when the reaction cup is picked up by the picking mechanism, the photoelectric separation blade moves from the first photoelectric switch to a position between the first photoelectric switch and the second photoelectric switch to stop, and the control terminal does not receive a signal sent by the second photoelectric switch within preset time, so that the reaction cup is judged to be picked up.
Through the scheme, the invention at least obtains the following technical effects:
according to the reaction cup grabbing device, the first photoelectric switch and the second photoelectric switch are arranged on the rack. The first photoelectric switch corresponds to the initial position of the picking mechanism, the second photoelectric switch corresponds to the position where the picking mechanism is abutted against the bearing platform because the reaction cup is not picked up by the picking mechanism, and the picking mechanism is provided with a photoelectric blocking piece.
The picking mechanism descends from the initial position, when the reaction cup is picked, the photoelectric separation blade cannot move to the second photoelectric switch and cannot trigger a signal of the second photoelectric switch, the control terminal does not receive the signal sent by the second photoelectric switch within the preset moving time of the picking mechanism, the reaction cup is judged to be successfully picked, and the grabbing device is instructed to carry out the next operation.
The picking mechanism descends from an initial position, when the reaction cup is not picked up, the photoelectric blocking sheet can move from the first photoelectric switch to the second photoelectric switch and trigger a signal of the second photoelectric switch, the control terminal receives the signal sent by the second photoelectric switch and judges that the reaction cup is not picked up, and the grabbing device is instructed to adjust to a preset position of another reaction cup to carry out picking operation.
The reaction cup grabbing device converts the blocking effect of the reaction cup on the picking mechanism into the movement distance of the photoelectric separation blade, and whether the reaction cup is picked up is judged by triggering the second photoelectric switch through the movement of the photoelectric separation blade. Compared with the mode of detecting the change of the pressure value, the time is shortened, the judgment time is shortened, and the working efficiency of the reaction cup gripping device is improved.
Preferably, the picking mechanism comprises a driving assembly, a buffering assembly and a picking assembly; the driving assembly is mounted on the rack, the picking assembly is in transmission connection with the driving assembly through the buffering assembly, and the buffering assembly is arranged on the sliding rail in a sliding manner; the driving assembly drives the buffer assembly to move up and down along the sliding rail, so that the picking assembly picks up the reaction cup.
Preferably, the driving assembly comprises a servo motor, a screw rod and a motor nut, the screw rod is connected to the output end of the servo motor in a shaft connection mode, and the motor nut is sleeved on the screw rod and in threaded fit with the screw rod; the buffer assembly is connected with the motor nut.
Preferably, the buffer assembly comprises a sliding block, a driven block, a buffer piece and a mounting frame; the driven piece with drive assembly is connected, the mounting bracket pass through the bolster with the driven piece is connected, the subassembly of picking up install in the mounting bracket, the mounting bracket pass through slider slidable mounting in the slide rail.
Preferably, the mounting frame comprises a top plate, a bottom plate and a connecting plate; the top plate and the bottom plate are fixedly connected through the connecting plate, the bottom surface of the top plate is abutted to the top surface of the driven block, and the buffer piece is arranged between the top surface of the bottom plate and the driven block.
Preferably, the buffer member includes a buffer guide shaft and a spring; the buffering guide shaft is fixedly arranged between the top plate and the bottom plate, the driven block is provided with a through hole and sleeved on the buffering guide shaft, and the spring is sleeved on the buffering guide shaft and positioned between the driven block and the bottom plate.
Preferably, the pick-up assembly comprises a suction cup and a vacuum joint; one end of the vacuum joint is connected with the sucker, and the other end of the vacuum joint is used for connecting a vacuum pump; the sucking disc provides a negative pressure adsorption reaction cup through a vacuum pump.
Preferably, the picking assembly further comprises a silica gel sheet, and the silica gel sheet is mounted on the surface of the adsorption end of the suction cup.
Preferably, the first photoelectric switch and the second photoelectric switch are both groove-type photoelectric switches, and the photoelectric blocking sheet triggers the groove-type photoelectric switches to generate induction signals when passing through a groove detection region of the groove-type photoelectric switches.
The invention aims to provide an immunoassay analyzer which can improve the working efficiency by accelerating the speed of judging whether reaction cups are successfully picked up by a reaction cup grabbing device.
The invention is realized by the following technical scheme:
an immunoassay analyzer comprises
The reaction cup grabbing device is the reaction cup grabbing device in any one of the schemes;
the reaction cup conveying device comprises an X-axis moving mechanism and a Y-axis moving mechanism, the X-axis moving mechanism moves along the Y-axis moving mechanism, and the reaction cup gripping device is mounted on the X-axis moving mechanism and can move along the X-axis moving mechanism; the reaction cup gripping device performs translational motion through the X-axis moving mechanism and the Y-axis moving mechanism.
Through the scheme, the invention at least obtains the following technical effects:
the immunoassay analyzer of the invention forms a three-dimensional reaction cup carrying system by the reaction cup gripping device and the reaction cup conveying device. The reaction cup grabbing device can pick up the reaction cup in the Z-axis direction and lift the reaction cup to a safe transportation height, and then the reaction cup transportation mechanism carries out translation transportation on the X axis and the Y axis to move the reaction cup to different detection positions.
Whether response cup grabbing device judges the judgement efficiency promotion of picking up the response cup successfully, can reduce the time of this immunoassay appearance single transport response cup, promotes immunoassay appearance's work efficiency.
The invention has the beneficial effects that:
compared with the traditional method for detecting the change of the pressure value, the reaction cup gripping device has higher feedback speed through the immediate feedback mode of the photoelectric signal, so that the judgment speed of the reaction cup gripping device for picking up the reaction cup each time is obviously shortened, and the working efficiency of the reaction cup gripping device is improved. The immunoassay analyzer provided by the invention is provided with the reaction cup gripping device, so that the time for judging whether the reaction cup is successfully picked up is shortened, and the working efficiency is further greatly improved.
Drawings
FIG. 1 is a schematic axial view of a cuvette holder according to an embodiment of the present invention.
FIG. 2 is a schematic second axial view of a cuvette handling apparatus according to an embodiment of the present invention.
FIG. 3 is a side view of a cuvette holding device according to an embodiment of the present invention.
FIG. 4 is a front sectional view of a cuvette holding apparatus according to an embodiment of the present invention.
FIG. 5 is an enlarged view of a portion of a cushioning assembly provided in one embodiment of the present invention.
FIG. 6 is a schematic view showing a combination of a cuvette holding means and a cuvette transport means according to an embodiment of the present invention.
Legend:
1, a frame; 2, a picking mechanism; 3 a sensor assembly; a 4X-axis moving mechanism; 5Y-axis moving mechanism; 6, a reaction cup;
11 a slide rail;
21 a drive assembly; 22 a cushioning component; 23 picking up the assembly;
31 a first photoelectric switch; 32 a second photoelectric switch; 33 a photoelectric barrier sheet;
211 a servo motor; 212 a screw rod; 213 motor nuts;
a 221 slider; 222 a follower block; 223 buffer member; 224 a mounting frame;
231 a suction cup; 232 a vacuum joint; 233 a silica gel sheet;
2231 a guide shaft; 2232 a spring;
2241 a top plate; 2242 a base plate; 2243 connecting the plates.
Detailed Description
The invention is further illustrated by the following figures and examples.
As shown in fig. 1 and 2, the present embodiment provides a cuvette handling apparatus, which includes a frame 1, a picking mechanism 2, a sensor assembly 3 and a control terminal; a plurality of bearing platforms are arranged in the immunoassay analyzer, and the reaction cups 6 are placed on the bearing platforms to wait for being picked up. The picking mechanism 2 is arranged on the frame 1 and can move up and down, the sensor component 3 detects the movement position of the picking mechanism 2 and transmits a feedback signal to the control terminal, and the control terminal judges whether the reaction cups 6 are successfully picked or not according to the signal. The reaction cup gripping device of the embodiment realizes instant feedback through a matching mode of the movement distance of the sensor and the picking mechanism 2, and has the advantages of short time, simple structure, easiness in maintenance and reduction of wrong judgment probability compared with a traditional mode of judging whether the reaction cup 6 is successfully picked or not by changing the pressure value.
As shown in fig. 1 and 2, the sensor assembly 3 includes a first photoelectric switch 31, a second photoelectric switch 32, and a photoelectric barrier 33. The first photoelectric switch 31 and the second photoelectric switch are both mounted on the frame 1, wherein the first photoelectric switch 31 is set corresponding to the initial position of the picking mechanism 2, the second photoelectric switch 32 is set corresponding to the position of the bottom end of the picking mechanism 2 when the bottom end of the picking mechanism 2 abuts against the bearing platform, or the second photoelectric switch 32 can also be set corresponding to a section of position interval of the picking mechanism 2, the position interval is an interval in which the distance between the picking mechanism 2 and the bearing platform is less than or equal to the height of the reaction cup 6, and the requirement can be met by ensuring that the distance between the first photoelectric switch 31 and the second photoelectric switch 32 is greater than the distance between the initial position of the picking mechanism 2 and the position of the picking mechanism 2 for picking up the reaction cup 6. The photoelectric barrier 33 is installed on the picking mechanism 2 and is respectively matched with the two photoelectric switches along with the movement of the picking mechanism 2.
As shown in fig. 1 and 2, each time the reaction cup 6 is picked up, the pick-up mechanism 2 starts from its initial position, so that the photoelectric barrier sheet 33 keeps a state of shielding the first photoelectric switch 31 when the pick-up mechanism 2 is in a standby state, thereby generating a normally-closed effect. That is, when the photoelectric barrier 33 is not separated from the first photoelectric switch 31, the second photoelectric switch 32 is blocked by a foreign object and the transmitted signal is invalid. Thus, misoperation or interference of foreign objects can be avoided.
As shown in fig. 1 and fig. 2, the pick-up mechanism 2 starts to move to make the photoelectric barrier 33 separate from the first photoelectric switch 31, and the control terminal receives the signal change at the first photoelectric switch 31, thereby activating the detection for determining whether the cuvette 6 is picked up and determining whether the signal of the second photoelectric switch 32 is received.
As shown in fig. 1 and fig. 2, when there is a reaction cup 6 on the carrying platform, the picking mechanism 2 descends to the reaction cup 6 and picks up the reaction cup 6, the reaction cup 6 abuts against the picking mechanism 2 so that it cannot move downwards, the moving distance of the photoelectric barrier 33 is smaller than the distance between the two photoelectric switches, the photoelectric barrier 33 cannot change the signal of the second photoelectric switch 32, and the control terminal does not receive the signal of the second photoelectric switch 32 within the predetermined moving time of the picking mechanism 2 and determines that the picking mechanism 2 successfully picks up the reaction cup 6.
As shown in fig. 1 and 2, when there is no cuvette 6 on the supporting platform, the picking mechanism 2 is not blocked by the cuvette 6 in the descending process, the moving distance of the photoelectric barrier 33 may be greater than or equal to the distance between the two photoelectric switches, that is, the photoelectric barrier 33 may move from the first photoelectric switch 31 to the second photoelectric switch 32 at the initial position, and further, the photoelectric barrier 33 blocks the light of the second photoelectric switch 32 to trigger the signal. The control terminal determines that the picking mechanism 2 fails to pick up the reaction cup 6 after receiving the signal.
As shown in fig. 2, in an embodiment, the frame 1 is mounted on a slide rail 11, and the slide rail 11 is longitudinally disposed, so that the picking mechanism 2 slides along the slide rail 11, and the shaking of the picking mechanism 2 during the lifting process can be reduced to improve the stability. The problem that the reaction cup 6 falls off due to the shaking of the picking mechanism 2 is avoided.
As shown in fig. 2, in one embodiment, the picking mechanism 2 includes a drive assembly 21, a buffer assembly 22, and a picking assembly 23. The driving assembly 21 is installed on the frame 1, the buffer assembly 22 is connected with the output end of the driving assembly 21, the pick-up assembly 23 is connected with the buffer assembly 22, and the buffer assembly 22 can play a role in buffering impact between the driving assembly 21 and the pick-up assembly 23. The buffer mechanism is also slidably mounted on the slide rail 11, so that the buffer assembly 22 and the picking assembly 23 both slide along the slide rail 11, and the picking assembly 23 contacts and picks up the reaction cup 6. Since the picking assembly 23 is blocked by the reaction cup 6 and cannot move further downwards when picking up the reaction cup 6 when the reaction cup 6 is on the carrying platform, the driving assembly 21 still continuously outputs power to push the buffer assembly 22, and the reaction cup 6 can be prevented from being crushed by the contraction and buffering of the buffer assembly 22.
As shown in fig. 3 and 4, in one embodiment, the driving assembly 21 includes a servo motor 211, a lead screw 212, and a motor nut 213. The servo motor 211 is fixed on the frame 1, the output end of the servo motor 211 is coupled with the lead screw 212, the motor nut 213 is sleeved on the lead screw 212 and forms a threaded fit, and the buffer assembly 22 is connected with the motor nut 213. The servo motor 211 drives the screw rod 212 to rotate, and since the motor nut 213 is connected to the buffer assembly 22 and cannot rotate, the motor nut 213 and the screw rod 212 rotate relatively, and the motor nut 213 generates a displacement effect relative to the screw rod 212, and the displacement effect pushes the buffer assembly 22 to slide along the slide rail 11.
As shown in fig. 3 and 5, in one embodiment, the damping assembly 22 includes a slider 221, a follower 222, a damper 223, and a mounting bracket 224. Driven piece 222 is fixedly connected with motor nut 213, mounting bracket 224 is connected with pickup assembly 23, and buffer member 223 is arranged between driven piece 222 and mounting bracket 224 to play a buffer role. One side of the sliding block 221 is slidably connected to the sliding rail 11, and the other side is fixedly connected to the mounting frame 224. The buffer assembly 22 and the pickup assembly 23 are moved along the slide rail 11 by the slider 221.
As shown in fig. 3 and 5, according to the above-mentioned embodiment, the mounting frame 224 includes a top plate 2241, a bottom plate 2242, and a connecting plate 2243, wherein the top plate 2241 is parallel to the bottom plate 2242, and the connecting plate 2243 is perpendicular to and fixedly connects the two plates. The connecting plate 2243 is fixedly connected with the sliding block 221, so that the mounting frame 224 is fixed with the sliding block 221. The bottom surface of the top plate 2241 abuts against the top surface of the driven block 222, the driven block 222 is confined between the top plate 2241 and the bottom plate 2242, and the cushion member 223 is provided between the bottom surface of the driven block 222 and the top surface of the bottom plate 2242.
As shown in fig. 3 and 4, when the driving assembly 21 drives the buffer assembly 22 and the picking assembly 23 to move downwards, so that the picking assembly 23 picks up the reaction cup 6 and is blocked by the reaction cup 6 from moving, the mounting frame 224 is kept still in synchronization with the picking assembly 23, the driven block 222 continues to move downwards along with the motor nut 213, and the buffer 223 is squeezed.
As shown in fig. 3 and 4, when the driving assembly 21 drives the buffer assembly 22 and the picking assembly 23 to move upward, so that the picking assembly 23 lifts the reaction cup 6, the driven piece 222 moves upward along with the motor nut 213, and the driven piece 222 abuts against the bottom surface of the top plate 2241 of the mounting frame 224, thereby raising the mounting frame 224. This kind of mode of lifting mounting bracket 224 from follower 222 makes the process of lifting up reaction cup 6 more stable, avoids reaction cup 6 to rock and drops.
As shown in fig. 3 and 4, according to the above embodiment, the buffer member 223 needs to bear pressure and maintain the moving direction of the picking assembly 23, so as to avoid the picking assembly 23 from being skewed due to the deflection of the buffer member 223, and ensure that the picking assembly 23 can accurately pick up the reaction cups 6. Therefore, the buffer member 223 includes a guide shaft 2231 and a spring 2232, the guide shaft 2231 is fixedly installed between the top plate 2241 and the bottom plate 2242, and the driven block 222 is provided with a through hole and sleeved on the guide shaft 2231, so that the driven block 222 can only slide along the guide shaft 2231. The spring 2232 is sleeved on the guide shaft 2231 and located between the driven block 222 and the bottom plate 2242, and the spring 2232 always provides a supporting force for the driven block 222. When the mounting bracket 224 is fixed and the driven piece 222 moves downward with the motor nut 213, the driven piece 222 slides along the guide shaft 2231 and compresses the spring 2232, and the spring 2232 provides a damping effect.
As shown in FIG. 3, in one embodiment, the pick-up assembly 23 includes a suction cup 231 and a vacuum fitting 232. One end of the vacuum connector 232 is connected with the suction cup 231, and the other end is connected with the vacuum pump. Air is sucked by a vacuum pump, and a negative pressure suction force is generated at the suction cup 231 to suck the reaction cup 6. The suction end surface of the suction cup 231 is provided with a silicon sheet 233, so that the air tightness of the suction cup 231 is enhanced, and the suction effect of the suction cup 231 on the reaction cup 6 is enhanced.
As shown in fig. 1, in one embodiment, the first and second photoelectric switches 31 and 32 are both groove-type photoelectric switches, i.e., the light emitting portion and the sensing portion are disposed opposite to each other with the light path between them. The photoelectric barrier sheet 33 blocks the light path trigger signal when passing between the light emitting section and the sensing section. The photoelectric switch can reduce the false triggering probability.
As shown in FIG. 6, in one embodiment there is also provided an immunoassay analyzer comprising
The reaction cup grabbing device is the reaction cup grabbing device in any one of the embodiments;
the reaction cup conveying device comprises an X-axis moving mechanism 4 and a Y-axis moving mechanism 5, the X-axis moving mechanism 4 moves along the Y-axis moving mechanism 5, and the reaction cup gripping device is mounted on the X-axis moving mechanism 4 and can move along the X-axis moving mechanism 4; the reaction cup gripping device carries out translational motion through an X-axis moving mechanism 4 and a Y-axis moving mechanism 5.
After the cuvette 6 is picked up and lifted by the cuvette holding means in the Z-axis direction, the cuvette 6 is transported in the X-axis direction and/or the Y-axis direction in the horizontal direction by the cuvette transport means, thereby transporting the cuvette 6 from one detection site to another detection site.
Various technical features in the above embodiments may be arbitrarily combined as long as there is no conflict or contradiction in the combination between the features, but is limited to the space and is not described one by one.
The present invention is not limited to the above-described embodiments, and various changes and modifications of the present invention are intended to be included within the scope of the claims and the equivalent technology of the present invention if they do not depart from the spirit and scope of the present invention.

Claims (10)

1. The utility model provides a reaction cup grabbing device which characterized in that: comprises that
The device comprises a rack, a driving device and a control device, wherein the rack is provided with a slide rail;
the picking mechanism is slidably mounted on the sliding rail and is used for picking up the reaction cups placed on the bearing platform;
the sensor assembly comprises a first photoelectric switch, a second photoelectric switch and a photoelectric blocking piece, wherein the first photoelectric switch and the second photoelectric switch are both arranged on the rack, the first photoelectric switch is arranged corresponding to the initial position of the picking mechanism, and the distance between the first photoelectric switch and the second photoelectric switch is greater than the distance between the initial position of the picking mechanism and the position of the picking mechanism for picking up the reaction cup and is less than or equal to the distance between the initial position of the picking mechanism and the position of the bottom end of the picking mechanism when the picking mechanism is abutted against the bearing platform; the photoelectric blocking piece is arranged on the picking mechanism, and moves along with the picking mechanism to be respectively matched with the first photoelectric switch and the second photoelectric switch;
the control terminal is respectively in communication connection with the pickup mechanism, the first photoelectric switch and the second photoelectric switch;
when the reaction cup is not picked up by the picking mechanism, the photoelectric separation blade moves from the first photoelectric switch to the second photoelectric switch, and the control terminal receives a signal of the second photoelectric switch to judge that the reaction cup is not picked up;
when the reaction cup is picked up by the picking mechanism, the photoelectric separation blade moves from the first photoelectric switch to a position between the first photoelectric switch and the second photoelectric switch to stop, and the control terminal does not receive a signal sent by the second photoelectric switch within preset time, so that the reaction cup is judged to be picked up.
2. The cuvette holding device according to claim 1, wherein: the picking mechanism comprises a driving assembly, a buffering assembly and a picking assembly; the driving assembly is mounted on the rack, the picking assembly is in transmission connection with the driving assembly through the buffering assembly, and the buffering assembly is arranged on the sliding rail in a sliding manner; the driving assembly drives the buffer assembly to move up and down along the sliding rail, so that the picking assembly picks up the reaction cup.
3. The cuvette holding device according to claim 2, wherein: the driving assembly comprises a servo motor, a screw rod and a motor nut, the screw rod is connected to the output end of the servo motor in a shaft connection mode, and the motor nut is sleeved on the screw rod and in threaded fit with the screw rod; the buffer assembly is connected with the motor nut.
4. The cuvette holding device according to claim 2, wherein: the buffer assembly comprises a sliding block, a driven block, a buffer piece and a mounting frame; the driven piece with drive assembly is connected, the mounting bracket pass through the bolster with the driven piece is connected, the subassembly of picking up install in the mounting bracket, the mounting bracket pass through slider slidable mounting in the slide rail.
5. The cuvette holding device according to claim 4, wherein: the mounting rack comprises a top plate, a bottom plate and a connecting plate; the top plate and the bottom plate are fixedly connected through the connecting plate, the bottom surface of the top plate is abutted to the top surface of the driven block, and the buffer piece is arranged between the top surface of the bottom plate and the driven block.
6. The cuvette holding device according to claim 5, wherein: the buffer piece comprises a buffer guide shaft and a spring; the buffering guide shaft is fixedly arranged between the top plate and the bottom plate, the driven block is provided with a through hole and sleeved on the buffering guide shaft, and the spring is sleeved on the buffering guide shaft and positioned between the driven block and the bottom plate.
7. The cuvette holding device according to claim 2, wherein: the picking assembly comprises a suction cup and a vacuum joint; one end of the vacuum joint is connected with the sucker, and the other end of the vacuum joint is used for connecting a vacuum pump; the sucking disc provides a negative pressure adsorption reaction cup through a vacuum pump.
8. The cuvette holding device according to claim 7, wherein: the picking assembly further comprises a silica gel sheet, and the silica gel sheet is installed on the surface of the adsorption end of the sucker.
9. The cuvette holding device according to claim 1, wherein: the first photoelectric switch and the second photoelectric switch are both groove-shaped photoelectric switches, and the photoelectric blocking pieces trigger the groove-shaped photoelectric switches to generate induction signals when passing through groove detection areas of the groove-shaped photoelectric switches.
10. An immunoassay analyzer, characterized in that: comprises that
A reaction cup gripping device, wherein the reaction cup gripping device is the reaction cup gripping device of any one of the claims 1 to 9;
the reaction cup conveying device comprises an X-axis moving mechanism and a Y-axis moving mechanism, the X-axis moving mechanism moves along the Y-axis moving mechanism, and the reaction cup gripping device is mounted on the X-axis moving mechanism and can move along the X-axis moving mechanism; the reaction cup gripping device performs translational motion through the X-axis moving mechanism and the Y-axis moving mechanism.
CN202111600759.XA 2021-12-24 2021-12-24 Reaction cup grabbing device and immunoassay appearance Pending CN114414821A (en)

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Application Number Priority Date Filing Date Title
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115308429A (en) * 2022-10-09 2022-11-08 广州国家实验室 Reaction cup, sample transfer device and sample transfer method
CN117169487A (en) * 2023-11-03 2023-12-05 山东康华生物医疗科技股份有限公司 Reaction cup grabbing and moving mechanism
CN117805419A (en) * 2024-02-29 2024-04-02 山东康华生物医疗科技股份有限公司 Rotatory compound reaction cup device of snatching

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115308429A (en) * 2022-10-09 2022-11-08 广州国家实验室 Reaction cup, sample transfer device and sample transfer method
CN117169487A (en) * 2023-11-03 2023-12-05 山东康华生物医疗科技股份有限公司 Reaction cup grabbing and moving mechanism
CN117169487B (en) * 2023-11-03 2024-01-23 山东康华生物医疗科技股份有限公司 Reaction cup grabbing and moving mechanism
CN117805419A (en) * 2024-02-29 2024-04-02 山东康华生物医疗科技股份有限公司 Rotatory compound reaction cup device of snatching

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