CN114403944A - Closed tongue scraping type saliva DNA sampler - Google Patents

Abstract

The invention discloses a closed tongue scraping type saliva DNA sampler, belonging to the field of experimental appliances, comprising a collecting tube, wherein the upper end of the collecting tube is in threaded connection with a preserving fluid bottle cap, the lower end of the preserving fluid bottle cap is in sliding connection with a handheld rod, the lower end of the handheld rod is fixedly connected with a buccal liquid sucking ball extending into the collecting tube, the cell falling on the tongue of a user can be effectively promoted through the matching of the buccal liquid sucking ball, an eccentric impact ball shell, a tongue scraping slide bar and a wrapping type liquid storage bag, the number of samples containing the fallen cells in the saliva is increased, the sampling success rate is improved, the authenticity of gold detection data can be effectively ensured, the sampling mode can be changed, the experience feeling of the user can be effectively improved through the closed sampling mode, the tongue can be continuously stimulated through the matching of the tongue scraping slide bar and the tongue sticking bag, and the saliva secretion amount of the oral cavity can be increased, thereby improving the sampling efficiency and reducing the waiting time of the user.

Description

Closed tongue scraping type saliva DNA sampler

Technical Field

The invention relates to the field of experimental instruments, in particular to a closed tongue scraping type saliva DNA sampler.

Background

The gene detection (DNA detection) is a technique for detecting DNA by blood, other body fluids or cells, and is a method for taking peripheral venous blood or other tissue cells of a detected person, amplifying the gene information, detecting DNA molecular information in the cells of the detected person by a specific device, and analyzing whether the gene type, the gene defect and the expression function contained in the DNA molecular information are normal or not, so that people can know the gene information of themselves, and can determine the cause of disease or predict the risk of the body to suffer from a certain disease.

The most commonly used DNA sample collection mode of gene detection sampling is saliva sampling, it is because compare in blood collection saliva collection more convenient and free, the event is more accepted by people than blood sampling, the multi-purpose saliva DNA sample thief of saliva sampling is as sampling utensil, saliva DNA sample thief is mainly by gathering the funnel, sampling pipe and tube cap are constituteed, it has saliva DNA preservative fluid to persist in the tube cap, saliva in order to guarantee to gather can preserve for a long time at normal atmospheric temperature, effectively improve the security of saliva sampling and the precision of testing data.

The extraction of DNA in the saliva sample is through the exfoliative cell that the saliva contains, and not saliva itself, therefore the mode that saliva was carried out the sample storage is spitted into to the sampling funnel through people voluntarily to current saliva DNA sample thief, can not effectively guarantee to have the content of exfoliative cell in the saliva sample, and then has reduced the success rate of sampling, influences the data authenticity of gene detection.

Disclosure of Invention

1. Technical problem to be solved

Aiming at the problems in the prior art, the invention aims to provide a closed tongue scraping type saliva DNA sampler, which can effectively promote the cells on the tongue of a user to fall off and increase the number of samples containing the fallen cells in saliva by matching of a buccal liquid sucking ball, an eccentric impact ball shell, a tongue scraping sliding rod and a wrapping type liquid storage bag, improve the sampling success rate, effectively ensure the authenticity of fund detection data, change the sampling mode, effectively improve the experience of the user by the closed sampling mode, continuously stimulate the tongue by matching of the tongue scraping sliding rod and a tongue sticking bag, increase the saliva secretion amount in the oral cavity, further improve the sampling efficiency and reduce the waiting time of the user.

2. Technical scheme

In order to solve the above problems, the present invention adopts the following technical solutions.

The utility model provides a close mouthful and scrape tongue formula saliva DNA sample thief, includes the collection pipe, collection pipe upper end threaded connection has the preserving fluid bottle lid, preserving fluid bottle lid lower extreme sliding connection has handheld stick, handheld stick lower extreme fixedly connected with extends to the intraductal imbibition ball of collection, and holds and set up a plurality of evenly distributed's imbibition micropore on the imbibition ball, hold and set up the stock solution chamber that communicates with the imbibition micropore in the imbibition ball, handheld stick lower extreme extends to the stock solution intracavity, and fixedly connected with elasticity adapter sleeve, elasticity adapter sleeve lower extreme fixedly connected with eccentric striking spherical shell, eccentric striking spherical shell outer end middle part sliding connection has a plurality of evenly distributed scrapes the tongue slide bar, scrape the tongue slide bar and keep away from eccentric striking spherical shell one end fixedly connected with and scrape the tongue counter weight pearl, hold imbibition ball outer end fixedly connected with a plurality of and scrape tongue counter weight matched with subsides the tongue drum package, eccentric striking spherical shell outer end fixedly connected with hold imbibition ball matched with parcel formula reservoir, through holding the imbibition ball, eccentric striking spherical shell, scrape the cooperation of tongue slide bar and parcel formula reservoir, can effectively promote the cell on the user's tongue to drop, increase the sample quantity that contains the cell that drops in the saliva, improve the sampling success rate, when effectively guaranteeing fund detection data's authenticity, can also change the mode of sample, the experience sense of user is effectively improved through the mode of closing the mouth sample, and can be through scraping the tongue slide bar and pasting the continuous amazing tongue of cooperation of tongue drum package, increase the volume of oral cavity secretion saliva, and then improve sampling efficiency, reduce user's latency.

Further, it has been seted up a plurality of tongue holes of scraping to hold imbibition ball outer end, scrape the guiding tube that the downthehole fixedly connected with of tongue extended to the stock solution intracavity, guiding tube outer end and subsides tongue swell fixed connection, and scrape the tongue counter weight pearl and run through the guiding tube and extend to in the subsides tongue swell, scrape the tongue slide bar and scrape the tongue counter weight pearl through the guiding tube and guide, when pressing extrusion saliva sample to the oral cavity containing imbibition ball for scrape the tongue counter weight pearl and scrape the tongue slide bar and have the synchronism, can make the saliva fully with scrape the tongue slide bar contact, improve the content of the cell that drops in the saliva sample, improve the success rate of taking a sample.

Further, scrape a plurality of supporting force sand grips of tongue counter weight pearl near pasting a tongue swell one end fixedly connected with, paste and offer a plurality ofly on the tongue swell with supporting force sand grip matched with shrink micropore, receiving the eccentric pressure when rotating, the supporting force sand grip can spread handheld stick through shrink micropore, and then strengthens the excitement sense to the tongue, scrapes the tongue effect in the improvement, when promoting the cell and drop, has still effectively promoted the secretion of saliva for it can effectively be applicable to the user that the young or can not take care of oneself to hold the imbibition ball, improves the suitability of sucking the imbibition ball.

Further, fixedly connected with decides power piece in the eccentric striking spherical shell, decide a plurality of stretching force telescopic strips of power piece outer end fixedly connected with, stretch force telescopic strip outer end fixedly connected with eccentric arc piece, and eccentric arc piece outer end with scrape tongue slide bar fixed connection, through the eccentric settings of eccentric arc piece, constantly pivoted sucking the liquid ball sucking for eccentric arc piece produces eccentric power, promotes to scrape the stimulation of tongue counter weight pearl to the tongue, and the area of tongue is scraped in the increase, and then effectively increases the accuracy of gene detection data.

Furthermore, both ends are a plurality of balanced silk all fixedly connected with around the liquid storage chamber, and both ends are a plurality of around the balanced silk fixedly connected with breathe supplementary sliding ring cover, breathe supplementary sliding ring cover comprises a plurality of flower type sliding rings, and flower type sliding ring outer end sliding connection has a plurality of supplementary sliding beads.

Further, stock solution intracavity wall fixedly connected with a plurality of with breathe supplementary sliding ring cover matched with breathe the cushion, and breathe the shape of cushion and the curve of flower type sliding ring and laminate mutually, sucking liquid ball pivoted in-process sucking, supplementary slippery pearl can constantly slide at the flower type sliding ring, and then constantly acts on and breathes the cushion for breathe the cushion and produce the fluctuation action, promote to suck the absorption of liquid ball and parcel formula reservoir to saliva, improve the efficiency of saliva sampling.

Further, the upper end of the liquid storage bottle cap is provided with a display hole, and the lower end of the display hole is connected with a handheld rod in a sliding mode and is in interference fit with the handheld rod.

Further, the display hole upper end sliding connection has a color development plugging strip, color development plugging strip lower extreme fixedly connected with tears the strip, tear strip lower extreme and handheld stick fixed connection, the spacing separation blade of color development plugging strip upper end fixedly connected with.

Further, it develops colour to have seted up the vacuum colour development chamber in the colour development shutoff strip, and tears the strip upper end and extend to the vacuum colour development intracavity, the colour development shutoff strip is made for transparent material, vacuum colour development intracavity wall is stained with the sodium discoloration layer, and after sucking the imbibition ball and taking out, it can drive the vacuum colour development chamber in the colour development shutoff strip and break to tear the strip, then makes outside air get into inside, and the sodium discoloration layer produces the oxidation and discolours, and the medical personnel of being convenient for carry out quick classification to subsequent saliva DNA sample thief, effectively avoids using the saliva DNA sample thief around mixing.

In addition, the invention also discloses a use method of the closed tongue scraping type saliva DNA sampler, which comprises the following steps:

s1, a user firstly unscrews a collection tube and a preservation solution bottle cap, and pulls a hand-held rod;

s2, separating the color-developing sealing strip from the handheld rod, and taking out the buccal imbibition ball;

s3, putting the buccal imbibition ball into the mouth by a user, and driving the buccal imbibition ball to rotate by the handheld rod;

s4, stimulating the tongue of the user and scraping cells on the tongue through the matching of the eccentric impact spherical shell, the tongue scraping slide rod and the fixed force block, and adsorbing saliva with the fallen cells into a liquid storage cavity of the buccal imbibition ball;

s5, after rotating for a period of time, taking out the buccal imbibition ball from the mouth, placing the buccal imbibition ball in the collection tube, pressing the buccal imbibition ball by using a handheld stick to extrude saliva samples stored in the buccal imbibition ball into the buccal imbibition ball, taking out the buccal imbibition ball, and placing the buccal imbibition ball at a recovery point;

s6, then to the intraductal preservative fluid that adds of collection, screw up the preservative fluid bottle lid again to the collection pipe on, preserve liquid and saliva sample intensive mixing when rocking the collection pipe, the sample is accomplished, through the mode of the sample of closing the mouth, effectively improves traditional sampling mode, increases the hommization of saliva sample, reduces user's uncomfortable and feels to can effectively be applicable to the user that the young or can not take care of oneself.

3. Advantageous effects

Compared with the prior art, the invention has the advantages that:

(1) this scheme is through sucking the imbibition ball, eccentric striking spherical shell, scrape the cooperation of tongue slide bar and parcel formula reservoir, cell that can effectively promote on the user's tongue drops, the sample quantity who contains the cell that drops in the increase saliva, improve the sampling success rate, when effectively guaranteeing the authenticity of fund detection data, can also change the mode of sample, the experience sense of user is effectively improved to the mode through closing the mouth sample, and can constantly amazing the tongue through the cooperation of scraping the tongue slide bar and pasting the tongue swell, increase the oral cavity amount of secreting saliva, and then improve sampling efficiency, user's latency is reduced.

(2) Scrape the tongue slide bar and scrape tongue counter weight pearl through the guide tube and guide, when pressing the saliva sample of extruding to the mouth contains the imbibition ball for scrape tongue counter weight pearl and scrape the tongue slide bar and have the synchronism, can make saliva abundant with scrape the contact of tongue slide bar, improve the content of the cell that drops in the saliva sample, improve the success rate of taking a sample.

(3) Receiving the eccentric pressure when rotating, the holding power sand grip can spread handheld stick through the shrink micropore, and then strengthens the stimulus to the tongue, scrapes the tongue effect in the improvement, when promoting the cell and drop, has still effectively promoted the secretion of saliva for suck the imbibition ball can effectively be applicable to the user that the young or can not manage by oneself, improve and suck the suitability of imbibition ball.

(4) Through the eccentric setting of eccentric arc piece, constantly pivoted sucking the imbibition ball for eccentric arc piece produces eccentric force, promotes to scrape the stimulation of tongue counter weight pearl to the tongue, increases the area of scraping the tongue, and then effectively increases gene detection data's accuracy.

(5) Sucking the imbibition ball pivoted in-process, supplementary smooth pearl can constantly slide at the flower type sliding ring, and then constantly act on and breathe the cushion for breathe the cushion and produce the fluctuation action, promote to suck the imbibition ball and the absorption of parcel formula reservoir to saliva, improve the efficiency of saliva sampling.

(6) After sucking the imbibition ball and taking out, tear the strip and can drive the vacuum color development chamber of color development shutoff strip and break, then make outside air get into inside, the sodium discoloration layer produces the oxidation and discolours, and the medical personnel of being convenient for carries out quick classification to subsequent saliva DNA sample thief, and the saliva DNA sample thief around effectively avoiding using is mixed up.

Drawings

FIG. 1 is a schematic diagram of an axial structure of a saliva DNA sampler according to the present invention;

FIG. 2 is a schematic flow chart of a saliva sampling method according to the present invention;

FIG. 3 is a schematic view of a buccal imbibition ball spindle structure of the present invention;

FIG. 4 is a schematic view of a cross-sectional structure of a buccal liquid-absorbing ball according to the present invention;

FIG. 5 is a schematic diagram of the structure at A in FIG. 4 according to the present invention;

FIG. 6 is a schematic sectional view of the eccentric impact ball shell according to the present invention;

FIG. 7 is a schematic axial view of the breathing assistance slip ring cover of the present invention;

FIG. 8 is a schematic structural view of the buccal liquid-absorbing ball of the present invention in use;

FIG. 9 is a schematic view of the color-developing plugging strip of the present invention showing a schematic structure in a front view.

The reference numbers in the figures illustrate:

1 collection tube, 2 preserve liquid bottle lid, 201 color development blocking strip, 3 hold imbibition ball, 301 handheld stick, 302 paste tongue swell, 303 guide tube, 4 eccentric striking spherical shell, 401 elasticity adapter sleeve, 5 scrape tongue slide bar, 501 scrape tongue counter weight pearl, 502 prop power sand grip, 6 decide power piece, 601 eccentric arc piece, 602 prop power telescopic strip, 7 breathe supplementary slip ring covers, 701 supplementary slip pearl, 702 balance silk, 8 breathe the elastic pad, 9 parcel formula reservoir.

Detailed Description

The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention; it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments, and all other embodiments obtained by those skilled in the art without any inventive work are within the scope of the present invention.

In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "top/bottom", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "disposed," "sleeved/connected," "connected," and the like are to be construed broadly, e.g., "connected," which may be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.

Example 1:

referring to fig. 1-9, a closed scraping tongue type saliva DNA sampler comprises a collection tube 1, the upper end of the collection tube 1 is connected with a preserving fluid bottle cap 2 by screw thread, the lower end of the preserving fluid bottle cap 2 is connected with a hand-held rod 301 in a sliding manner, the lower end of the hand-held rod 301 is fixedly connected with a buccal imbibing ball 3 extending into the collection tube 1, the buccal imbibing ball 3 is provided with a plurality of imbibing micropores uniformly distributed, a liquid storage cavity communicated with the imbibing micropores is arranged in the buccal imbibing ball 3, the lower end of the hand-held rod 301 extends into the liquid storage cavity and is fixedly connected with an elastic adapter sleeve 401, the lower end of the elastic adapter sleeve 401 is fixedly connected with an eccentric impact ball shell 4, the middle part of the outer end of the eccentric impact ball shell 4 is connected with a plurality of scraping tongue slide bars 5 uniformly distributed in a sliding manner, one end of the scraping tongue slide bar 5 far away from the eccentric impact ball shell 4 is fixedly connected with a scraping tongue counter weight ball 501, the buccal imbibing ball 3 is fixedly connected with a plurality of sticking tongue drum bags 302 matched with the scraping tongue counter weight balls 501, eccentric striking spherical shell 4 outer end fixedly connected with hold imbibition ball 3 matched with parcel formula reservoir 9, through holding imbibition ball 3, eccentric striking spherical shell 4, scrape tongue slide bar 5 and parcel formula reservoir 9's cooperation, can effectively promote the cell on the user's tongue to drop, increase the sample quantity that contains the cell that drops in the saliva, improve the sampling success rate, when effectively guaranteeing the authenticity of fund detection data, can also change the mode of sample, effectively improve user's experience through the mode of closing a mouthful sample and feel, and can be through scraping tongue slide bar 5 and the continuous amazing tongue of the cooperation of pasting tongue drum package 302, increase the volume of oral cavity secretion saliva, and then improve sampling efficiency, reduce user's latency.

Referring to fig. 3, 4 and 6, the outer end of the buccal imbibition ball 3 is provided with a plurality of tongue scraping holes, the inner part of each tongue scraping hole is fixedly connected with a guide tube 303 extending into the liquid storage cavity, the outer end of the guide tube 303 is fixedly connected with a tongue attaching bulge 302, a tongue scraping counterweight bead 501 penetrates through the guide tube 303 and extends into the tongue attaching bulge 302, the tongue scraping slide bar 5 and the tongue scraping counterweight bead 501 are guided by the guide tube 303, and when the buccal imbibition ball 3 is pressed to extrude a saliva sample, the tongue scraping counterweight bead 501 and the tongue scraping slide bar 5 are synchronous, so that the saliva can be fully contacted with the tongue scraping slide bar 5, the content of exfoliated cells in the saliva sample is improved, and the sampling success rate is improved.

Referring to fig. 5, a plurality of supporting force protruding strips 502 are fixedly connected to one end of a tongue scraping counterweight bead 501 close to a tongue attaching bulge 302, a plurality of shrinkage micropores matched with the supporting force protruding strips 502 are formed in the tongue attaching bulge 302, eccentric pressure is applied when the tongue attaching bulge is rotated, the supporting force protruding strips 502 can be transmitted out of a handheld rod 301 through the shrinkage micropores, stimulation to the tongue is further enhanced, the tongue scraping effect is improved, cell shedding is promoted, secretion of saliva is effectively promoted, the buccal imbibition ball 3 can be effectively suitable for young people or users who cannot take care of themselves, and the applicability of the buccal imbibition ball 3 is improved.

Referring to fig. 4 and 6, a fixed force block 6 is fixedly connected in the eccentric impact spherical shell 4, a plurality of supporting force expansion strips 602 are fixedly connected at the outer ends of the fixed force block 6, eccentric arc blocks 601 are fixedly connected at the outer ends of the supporting force expansion strips 602, the outer ends of the eccentric arc blocks 601 are fixedly connected with the tongue scraping slide bar 5, and the liquid sucking ball 3 continuously rotates while being held by the mouth through the eccentric arrangement of the eccentric arc blocks 601, so that the eccentric arc blocks 601 generate eccentric force, stimulation of the tongue scraping counterweight beads 501 to the tongue is promoted, the tongue scraping area is increased, and the accuracy of gene detection data is effectively increased.

Referring to fig. 3, 4 and 7, the front and rear ends of the liquid storage chamber are fixedly connected with a plurality of balance wires 702, a breathing-assisting slip-ring cover 7 is fixedly connected between the balance wires 702 at the front and rear ends, the breathing-assisting slip-ring cover 7 is composed of a plurality of flower-shaped slip rings, and the outer ends of the flower-shaped slip rings are slidably connected with a plurality of auxiliary slip beads 701.

Referring to fig. 3, the inner wall of the liquid storage cavity is fixedly connected with a plurality of breathing elastic pads 8 matched with the breathing auxiliary slip ring cover 7, the shapes of the breathing elastic pads 8 are fitted with the curve of the flower-shaped slip ring, and in the rotating process of the liquid sucking ball 3, the auxiliary slip beads 701 can continuously slide on the flower-shaped slip ring and further continuously act on the breathing elastic pads 8, so that the breathing elastic pads 8 generate fluctuation, absorption of saliva by the liquid sucking ball 3 and the wrapped liquid storage bag 9 is promoted, and the efficiency of saliva sampling is improved.

Referring to fig. 1 and 9, a display hole is formed in the upper end of the liquid storage bottle cap 2, and a hand-held rod 301 is slidably connected to the lower end of the display hole and is in interference fit with the hand-held rod 301.

Referring to fig. 1 and 9, the upper end of the display hole is slidably connected with a color-developing plugging strip 201, the lower end of the color-developing plugging strip 201 is fixedly connected with a tearing strip, the lower end of the tearing strip is fixedly connected with a handheld rod 301, and the upper end of the color-developing plugging strip 201 is fixedly connected with a limiting blocking piece.

Please refer to fig. 1 and fig. 9, a vacuum color developing cavity is formed in the color developing sealing strip 201, and the upper end of the tearing strip extends into the vacuum color developing cavity, the color developing sealing strip 201 is made of transparent material, a sodium color changing layer is adhered to the inner wall of the vacuum color developing cavity, after the sucking liquid sucking ball 3 is taken out, the tearing strip can drive the vacuum color developing cavity in the color developing sealing strip 201 to break, then the outside air enters the inside, the sodium color changing layer generates oxidative discoloration, the medical care personnel can rapidly classify the subsequent saliva DNA sampler conveniently, and the saliva DNA sampler before and after use is effectively avoided from being mixed.

Referring to fig. 1-9, a user puts a buccal imbibition ball 3 into the mouth, and rotates the hand-held rod 301 to drive the buccal imbibition ball 3 to rotate together, so that the eccentric impact ball shell 4, the tongue scraping slide bar 5 and the fixed force block 6 rotate synchronously, the tongue scraping slide bar 5 is squeezed under the action of the gravity of the eccentric arc block 601 and the eccentric force, so that the tongue scraping counterweight bead 501 continuously squeezes the tongue sticking bulge 302, the deformation of the tongue sticking bulge 302 is increased, the force supporting convex strip 502 is promoted to squeeze out the tongue sticking bulge 302, the tongue scraping of the user is also stimulated through the tongue sticking bulge 302 and the force supporting convex strip 502, and the content of exfoliated cells in the mouth of the user and the saliva secretion amount are promoted; under the action of continuous rotation, the auxiliary sliding ball 701 can slide on the flower-shaped sliding ring to continuously extrude the breathing elastic pad 8, under the action of elastic deformation of the breathing elastic pad 8, the breathing elastic pad 8 can repeatedly act, the absorption speed of the liquid storage cavity of the sucking liquid ball 3 and the wrapped liquid storage bag 9 to saliva is improved, the cells on the tongue of a user can be effectively promoted to fall off through matching of the sucking liquid ball 3, the eccentric impact ball shell 4, the tongue scraping sliding rod 5 and the wrapped liquid storage bag 9, the number of samples containing the fallen cells in the saliva is increased, the sampling success rate is improved, the authenticity of gold detection data is effectively guaranteed, the sampling mode can be changed, the experience feeling of the user is effectively improved through the mode of closed sampling, and the tongue can be stimulated through matching of the tongue scraping sliding rod 5 and the tongue attaching bag 302, the quantity of saliva secreted by the oral cavity is increased, so that the sampling efficiency is improved, and the waiting time of a user is reduced.

Referring to fig. 1, fig. 2 and fig. 8, the present invention also discloses a method for using a closed tongue-scraping saliva DNA sampler, comprising the following steps:

s1, a user firstly unscrews a collection tube 1 and a preservation solution bottle cap 2, and pulls a hand-held rod 301;

s2, separating the color-developing sealing strip 201 from the handheld rod 301, and taking out the buccal imbibition ball 3;

s3, putting the buccal imbibition ball 3 into the mouth by a user, and driving the buccal imbibition ball 3 to rotate by the handheld rod 301;

s4, stimulating the tongue of a user and scraping cells on the tongue through the matching of the eccentric impact ball shell 4, the tongue scraping slide rod 5 and the fixed force block 6, and adsorbing saliva with the fallen cells into a liquid storage cavity of the buccal imbibition ball 3;

s5, after rotating for a period of time, taking the buccal imbibition ball 3 out of the mouth, placing the buccal imbibition ball in the collection tube 1, pressing the buccal imbibition ball 3 through the hand-held rod 301 to extrude a saliva sample stored in the buccal imbibition ball 3 into the buccal imbibition ball 3, taking the buccal imbibition ball 3 out, and placing the buccal imbibition ball at a recovery point;

s6, then to adding the preservative fluid in the collection pipe 1, screw up preservative fluid bottle lid 2 again to collection pipe 1 on, rock when gathering pipe 1 preservative fluid and saliva sample intensive mixing, the sample is accomplished, through the mode of the sample of closing the mouth, effectively improves traditional sampling mode, increases the hommization of saliva sample, reduces user's uncomfortable and feels to can effectively be applicable to the user that the young person perhaps can not take care of oneself.

The foregoing is only a preferred embodiment of the present invention; the scope of the invention is not limited thereto. Any person skilled in the art should be able to cover the technical scope of the present invention by equivalent or modified solutions and modifications within the technical scope of the present invention.

Claims (10)

1. The utility model provides a tongue formula saliva DNA sample thief is scraped to mouth that closes, includes collection pipe (1), collection pipe (1) upper end threaded connection has preserving fluid bottle lid (2), its characterized in that: the lower end of the preserving liquid bottle cap (2) is slidably connected with a handheld rod (301), the lower end of the handheld rod (301) is fixedly connected with a sucking liquid ball (3) extending into the collecting pipe (1) and provided with a plurality of liquid sucking micropores distributed uniformly, a liquid storage cavity communicated with the liquid sucking micropores is formed in the sucking liquid ball (3), the lower end of the handheld rod (301) extends into the liquid storage cavity and is fixedly connected with an elastic adapter sleeve (401), the lower end of the elastic adapter sleeve (401) is fixedly connected with an eccentric impact ball shell (4), the middle part of the outer end of the eccentric impact ball shell (4) is slidably connected with a plurality of evenly distributed tongue scraping slide bars (5), one end of the tongue scraping slide bar (5) far away from the eccentric impact ball shell (4) is fixedly connected with tongue scraping balance weight beads (501), the outer end of the sucking liquid ball (3) is fixedly connected with a plurality of tongue sticking and tongue stirring bags (302) matched with the tongue scraping balance weight beads (501), the outer end of the eccentric impact spherical shell (4) is fixedly connected with a wrapped liquid storage bag (9) matched with the buccal liquid suction ball (3).

2. The closed scraping tongue type saliva DNA sampler of claim 1, wherein: buccal imbibition ball (3) outer end has been seted up a plurality of tongue holes of scraping, scrape guiding tube (303) that the downthehole fixedly connected with of tongue extended to the stock solution intracavity, guiding tube (303) outer end and subsides tongue swell (302) fixed connection, and scrape tongue counter weight pearl (501) run through guiding tube (303) and extend to in subsides tongue swell (302).

3. The closed scraping tongue type saliva DNA sampler of claim 2, wherein: scrape tongue counter weight pearl (501) and be close to a plurality of supporting force sand grips (502) of close tongue bulge (302) one end fixedly connected with, set up a plurality of and supporting force sand grip (502) matched with shrink micropore on the tongue bulge (302).

4. The closed scraping tongue type saliva DNA sampler of claim 1, wherein: eccentric striking spherical shell (4) interior fixedly connected with decides power piece (6), decide a plurality of stay power telescopic strips (602) of power piece (6) outer end fixedly connected with, stay power telescopic strip (602) outer end fixedly connected with eccentric arc piece (601), and eccentric arc piece (601) outer end with scrape tongue slide bar (5) fixed connection.

5. The closed scraping tongue type saliva DNA sampler of claim 1, wherein: the equal fixedly connected with of both ends is a plurality of balance silk (702) around the stock solution chamber, and both ends are a plurality of around the balance silk (702) between fixedly connected with breathe supplementary sliding ring cover (7), breathe supplementary sliding ring cover (7) comprise a plurality of flower type sliding rings, and flower type sliding ring outer end sliding connection has a plurality of supplementary sliding beads (701).

6. The closed scraping tongue type saliva DNA sampler of claim 5, wherein: the inner wall of the liquid storage cavity is fixedly connected with a plurality of breathing elastic pads (8) matched with the breathing auxiliary slip ring cover (7), and the shapes of the breathing elastic pads (8) are attached to the curve of the flower-shaped slip ring.

7. The closed scraping tongue type saliva DNA sampler of claim 1, wherein: the display hole has been seted up to preserving liquid bottle lid (2) upper end, display hole lower extreme sliding connection has handheld stick (301) to be interference fit with handheld stick (301).

8. The closed scraping tongue type saliva DNA sampler of claim 7, wherein: the utility model discloses a display hole, including display hole upper end sliding connection have look shutoff strip (201), look shutoff strip (201) lower extreme fixedly connected with tears broken strip, tear broken strip lower extreme and handheld stick (301) fixed connection, the spacing separation blade of look shutoff strip (201) upper end fixedly connected with.

9. The closed scraping tongue type saliva DNA sampler of claim 8, wherein: the utility model discloses a vacuum color development blocking strip, including the color development blocking strip, be equipped with the vacuum color development chamber in color development blocking strip (201), and tear strip upper end and extend to the vacuum color development intracavity, color development blocking strip (201) are made for transparent material, vacuum color development intracavity wall is stained with the sodium discoloration layer.

10. The use method of the close scraping tongue type saliva DNA sampler as claimed in any one of claims 1-9, wherein: the method comprises the following steps:

s1, a user firstly unscrews a collection tube (1) and a preservation solution bottle cap (2), and pulls a hand-held rod (301);

s2, separating the color-developing blocking strip (201) from the handheld rod (301), and taking out the buccal imbibition ball (3);

s3, putting the buccal imbibition ball (3) into an inlet by a user, and driving the buccal imbibition ball (3) to rotate through the handheld rod (301);

s4, stimulating the tongue of a user and scraping cells on the tongue through the matching of the eccentric impact spherical shell (4), the tongue scraping slide rod (5) and the fixed force block (6), and adsorbing saliva with the fallen cells into a liquid storage cavity of the buccal imbibition ball (3);

s5, after rotating for a period of time, taking the buccal imbibition ball (3) out of the mouth, placing the buccal imbibition ball in the collection tube (1), pressing the buccal imbibition ball (3) through the hand-held rod (301) to extrude the saliva sample stored in the buccal imbibition ball into the buccal imbibition ball (3), taking the buccal imbibition ball (3) out, and placing the buccal imbibition ball at a recovery point;

s6, adding preservation liquid into the collection tube (1), screwing the preservation liquid bottle cap (2) onto the collection tube (1), and fully mixing the preservation liquid and the saliva sample when the collection tube (1) is shaken to finish sampling.

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