CN114364670B - 用于Cbl-b抑制的取代苄基-三唑类化合物及其进一步用途 - Google Patents

用于Cbl-b抑制的取代苄基-三唑类化合物及其进一步用途 Download PDF

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CN114364670B
CN114364670B CN202080060696.0A CN202080060696A CN114364670B CN 114364670 B CN114364670 B CN 114364670B CN 202080060696 A CN202080060696 A CN 202080060696A CN 114364670 B CN114364670 B CN 114364670B
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cell
cancer
cells
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CN114364670A (zh
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A·T·桑德斯
N·F·本斯
C·W·扎普夫
F·柯恩
王晨博
T·库敏斯
田中裕子
H·舒纳托纳
M·卡多佐
D·维斯
J·高斯灵
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Nulex Therapeutics
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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CN202080060696.0A 2019-06-26 2020-06-26 用于Cbl-b抑制的取代苄基-三唑类化合物及其进一步用途 Active CN114364670B (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962866914P 2019-06-26 2019-06-26
US62/866914 2019-06-26
US201962880285P 2019-07-30 2019-07-30
US62/880285 2019-07-30
US201962888870P 2019-08-19 2019-08-19
US201962888845P 2019-08-19 2019-08-19
US62/888870 2019-08-19
US62/888845 2019-08-19
PCT/US2020/039957 WO2020264398A1 (en) 2019-06-26 2020-06-26 Substituted benzyl-triazole compounds for cbl-b inhibition, and further uses thereof

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CN114364670B true CN114364670B (zh) 2025-06-13

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US (3) US11401267B2 (https=)
EP (1) EP3990117A1 (https=)
JP (1) JP7831995B2 (https=)
KR (1) KR20220026581A (https=)
CN (1) CN114364670B (https=)
AU (2) AU2020303696B2 (https=)
BR (1) BR112021026241A2 (https=)
CA (2) CA3294689A1 (https=)
IL (1) IL289290B1 (https=)
MX (2) MX2021015675A (https=)
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