CN114364667B - 用于Cbl-b抑制的3-取代哌啶类化合物以及Cbl-b抑制剂与癌症疫苗和/或溶瘤病毒联合的用途 - Google Patents

用于Cbl-b抑制的3-取代哌啶类化合物以及Cbl-b抑制剂与癌症疫苗和/或溶瘤病毒联合的用途 Download PDF

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CN114364667B
CN114364667B CN202080042301.4A CN202080042301A CN114364667B CN 114364667 B CN114364667 B CN 114364667B CN 202080042301 A CN202080042301 A CN 202080042301A CN 114364667 B CN114364667 B CN 114364667B
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cell
alkyl
cbl
cells
inhibitor
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CN114364667A (zh
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A·T·桑德斯
N·F·本斯
C·W·扎普夫
F·柯恩
王晨博
T·库敏斯
田中裕子
H·舒纳托纳
M·卡多佐
D·维斯
J·高斯灵
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Nulex Therapy
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CN202080042301.4A 2019-04-09 2020-04-09 用于Cbl-b抑制的3-取代哌啶类化合物以及Cbl-b抑制剂与癌症疫苗和/或溶瘤病毒联合的用途 Active CN114364667B (zh)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201962831392P 2019-04-09 2019-04-09
US62/831392 2019-04-09
US201962866909P 2019-06-26 2019-06-26
US62/866909 2019-06-26
US201962880267P 2019-07-30 2019-07-30
US62/880267 2019-07-30
US201962888870P 2019-08-19 2019-08-19
US201962888845P 2019-08-19 2019-08-19
US62/888870 2019-08-19
US62/888845 2019-08-19
PCT/US2020/027492 WO2020210508A1 (en) 2019-04-09 2020-04-09 3-substituted piperidine compounds for cbl-b inhibition, and use of a cbl-b inhibitor in combination with a cancer vaccine and/or oncolytic virus

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CN114364667B true CN114364667B (zh) 2025-01-10

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CN110790758A (zh) * 2018-08-01 2020-02-14 上海轶诺药业有限公司 一类具有免疫调节功能的含n杂环化合物的制备和应用
JP7600123B2 (ja) 2018-10-15 2024-12-16 ニューリックス セラピューティクス,インコーポレイテッド ユビキチンプロテオソーム経路を介してbtkを分解するための二官能性化合物
WO2020167518A1 (en) 2019-02-13 2020-08-20 Nurix Therapeutics, Inc. Bifunctional compounds for degrading btk via ubiquitin proteosome pathway
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