CN114258394A - 一种致癌性融合激酶抑制剂的晶型及其应用 - Google Patents
一种致癌性融合激酶抑制剂的晶型及其应用 Download PDFInfo
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- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
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- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
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Abstract
本发明公开了一种致癌性融合激酶抑制剂的晶型及其制备方法,并公开了其在制备治疗实体瘤相关疾病的药物中的应用。
Description
PCT国内申请,说明书已公开。
Claims (29)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (5)
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CN201910804019 | 2019-08-28 | ||
CN2019108040194 | 2019-08-28 | ||
CN2019108836226 | 2019-09-18 | ||
CN201910883622 | 2019-09-18 | ||
PCT/CN2020/111795 WO2021037156A1 (zh) | 2019-08-28 | 2020-08-27 | 一种致癌性融合激酶抑制剂的晶型及其应用 |
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CN114258394A true CN114258394A (zh) | 2022-03-29 |
CN114258394B CN114258394B (zh) | 2024-04-23 |
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US (1) | US20220289765A1 (zh) |
EP (1) | EP4023648A4 (zh) |
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WO (1) | WO2021037156A1 (zh) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101679429A (zh) * | 2007-04-18 | 2010-03-24 | 阿斯利康(瑞典)有限公司 | 5-氨基吡唑-3-基-3h-咪唑并[4,5-b]吡啶衍生物及其治疗癌的用途 |
CN102971322A (zh) * | 2010-05-20 | 2013-03-13 | 阵列生物制药公司 | 作为trk激酶抑制剂的大环化合物 |
CN107207514A (zh) * | 2014-12-15 | 2017-09-26 | 康联制药有限公司 | 稠环杂芳基化合物及其作为trk抑制剂的用途 |
CN111788205A (zh) * | 2018-02-28 | 2020-10-16 | 南京明德新药研发有限公司 | 吡唑并嘧啶衍生物及其用途 |
-
2020
- 2020-08-27 US US17/638,358 patent/US20220289765A1/en active Pending
- 2020-08-27 CN CN202080058668.5A patent/CN114258394B/zh active Active
- 2020-08-27 WO PCT/CN2020/111795 patent/WO2021037156A1/zh unknown
- 2020-08-27 EP EP20856096.1A patent/EP4023648A4/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101679429A (zh) * | 2007-04-18 | 2010-03-24 | 阿斯利康(瑞典)有限公司 | 5-氨基吡唑-3-基-3h-咪唑并[4,5-b]吡啶衍生物及其治疗癌的用途 |
CN102971322A (zh) * | 2010-05-20 | 2013-03-13 | 阵列生物制药公司 | 作为trk激酶抑制剂的大环化合物 |
CN107207514A (zh) * | 2014-12-15 | 2017-09-26 | 康联制药有限公司 | 稠环杂芳基化合物及其作为trk抑制剂的用途 |
CN111788205A (zh) * | 2018-02-28 | 2020-10-16 | 南京明德新药研发有限公司 | 吡唑并嘧啶衍生物及其用途 |
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WO2021037156A1 (zh) | 2021-03-04 |
CN114258394B (zh) | 2024-04-23 |
EP4023648A4 (en) | 2023-09-27 |
US20220289765A1 (en) | 2022-09-15 |
EP4023648A1 (en) | 2022-07-06 |
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