CN114246194A - Disinfectant for livestock and poultry breeding and preparation method thereof - Google Patents

Disinfectant for livestock and poultry breeding and preparation method thereof Download PDF

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Publication number
CN114246194A
CN114246194A CN202011017941.8A CN202011017941A CN114246194A CN 114246194 A CN114246194 A CN 114246194A CN 202011017941 A CN202011017941 A CN 202011017941A CN 114246194 A CN114246194 A CN 114246194A
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parts
weight
disinfectant
livestock
poultry breeding
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于洪忠
陈�峰
肖鹤
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Hunan Wuzhifeng Biochemistry Co ltd
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Hunan Wuzhifeng Biochemistry Co ltd
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/30Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/32Ingredients for reducing the noxious effect of the active substances to organisms other than pests, e.g. toxicity reducing compositions, self-destructing compositions
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02Amines; Quaternary ammonium compounds
    • A01N33/12Quaternary ammonium compounds
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/40Liliopsida [monocotyledons]
    • A01N65/42Aloeaceae [Aloe family] or Liliaceae [Lily family], e.g. aloe, veratrum, onion, garlic or chives

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Toxicology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention discloses a disinfectant for livestock and poultry breeding, which comprises a sterilizing agent, wherein the sterilizing agent comprises the following components in parts by weight: 165 parts of dodecyl dimethyl benzyl ammonium bromide, 165 parts of garlic oil and 980 parts of 1150, wherein the solvent comprises the following components in parts by weight: 18-25 parts of dimethylbenzene, 70-80 parts of dimethyl sulfoxide and 35-50 parts of dimethylformamide; the invention has the advantages of high sterilization efficiency and safer use.

Description

Disinfectant for livestock and poultry breeding and preparation method thereof
Technical Field
The invention relates to the technical field of disinfectants, in particular to a disinfectant for livestock and poultry breeding and a preparation method thereof.
Background
With the advance of the breeding industry to standardization, the healthy breeding of livestock and poultry is a major topic faced by vast livestock and veterinary workers, how to carry out pathogenic microorganisms of the farm is one of the important scientific research and practice directions, and the scientific research and the reasonable application of the disinfectant play an important role in purifying the farm.
The invention patent application with application publication number CN111066815A discloses a chlorine dioxide disinfectant special for livestock and poultry, which is prepared from the following raw materials in parts by weight: chlorite, monopersulfate, acidifying agent, bromide salt, stabilizing and forming agent and desiccant; wherein the chlorite is at least one of alkali metal salt of chlorous acid and alkaline earth metal salt of chlorous acid; the acidifying agent is at least one of sodium bisulfate, sodium bicarbonate, potassium bicarbonate and boric acid; the bromide salt is at least one selected from sodium bromide, lithium bromide, potassium bromide, calcium bromide, magnesium bromide, ammonium bromide and aluminum bromide; the stable forming agent comprises at least one of sodium sulfate, magnesium hydroxide, sodium chloride and magnesium chloride; the desiccant is at least one of calcium chloride, calcium sulfate and calcium stearate.
In view of the above-mentioned related technologies, the inventors believe that there exists a problem in that bromic acid is generated by a reaction of bromine-containing inorganic salt chlorite, and then chlorine dioxide is released to sterilize by using the sterilization characteristics of chlorine dioxide, but chlorine dioxide has strong oxidizing property and is easily decomposed to explode, which causes a great safety hazard.
Disclosure of Invention
Aiming at the defects in the prior art, the first object of the invention is to provide a disinfectant for livestock and poultry cultivation, which has the advantages of high sterilization efficiency and safer use.
In order to achieve the first object, the invention provides the following technical scheme: the disinfectant for livestock and poultry breeding comprises a sterilizing agent, wherein the sterilizing agent comprises the following components in parts by weight: 165 parts of dodecyl dimethyl benzyl ammonium bromide, 165 parts of garlic oil and 1150 parts of solvent.
By adopting the technical scheme, the compound solution obtained by directly compounding the garlic oil and the dodecyl dimethyl benzyl ammonium bromide has no irritation and strong antibacterial capability, has obvious inhibiting or killing effects on various pathogenic bacteria such as escherichia coli, bacillus cereus, diplococcus pneumoniae, streptococcus, pasteurella multocida, staphylococcus aureus, hemolytic streptococcus, escherichia coli, mycobacterium tuberculosis, vibrio cholerae and the like, and also has obvious effects on various antibiotic drug-resistant bacteria beads.
The garlic oil and the dodecyl dimethyl benzyl ammonium bromide are compounded to obtain the compound solution which can be directly sprayed to a farm in a spraying manner, and the compound solution is green, environment-friendly, convenient to operate and safer to use. In addition, the composition also has certain anti-inflammatory effect, and is not easy to generate drug resistance; can obviously improve the nutrition environment of epidermal cells, increase the activity of epidermal cells, play a role in beautifying the livestock and poultry epidermis and improve the color and health of the skin; the volatile components can be absorbed by animals, so that the immunity of the organism is improved, a certain deodorization effect can be achieved, the use comfort is improved, the irritation is reduced, the emotion of livestock and poultry is favorably pacified, and the influence on the livestock and poultry in the disinfection process is reduced.
Further, the solvent comprises the following components in parts by weight: 18-25 parts of dimethylbenzene, 70-80 parts of dimethyl sulfoxide and 35-50 parts of dimethylformamide.
By adopting the technical scheme, the solvent compounded by the dimethylbenzene, the dimethyl sulfoxide and the dimethylformamide is non-toxic, more stable, complementary in advantages and not easy to volatilize, solves the problem that the dimethylbenzene is used independently to stimulate the respiratory tract, and can reduce the freezing point and improve the freezing resistance. The solvent compounded by the dimethylbenzene, the dimethyl sulfoxide and the dimethylformamide has good intersolubility with a compound solution of the garlic oil and the dodecyl dimethyl benzyl ammonium bromide, and can increase the extraction rate of sterilization components in the garlic oil, thereby promoting the sterilization efficiency. Meanwhile, sulfur dioxide released by the garlicin due to unstable property and gas released by other components can be absorbed, so that the stimulation to livestock and poultry is reduced, aromatic odor can be generated, the emotion of the livestock and poultry is further pacified, and the adverse effect on the livestock and poultry is reduced.
Further, the sterilizing agent also comprises 830-845 parts of an emulsifying agent, wherein the emulsifying agent comprises 25-30 parts of polyoxyethylene sorbitan monooleate and 50-65 parts of alkylphenol polyoxyethylene.
By adopting the technical scheme, the emulsifier obtained by compounding the polyoxyethylene sorbitan monooleate and the alkylphenol ethoxylates has stable performance, can improve the surface tension between each component phase in the solution, forms a substance of a uniform dispersion or an emulsified body, improves the extraction degree and the dispersion uniformity of effective antibacterial components, and also has the function of improving the anti-aging performance of the disinfectant. Furthermore, such a microstructure allows the solution to form an emulsified liquid of the "water-in-oil" type, which is more susceptible to contact and association with bacteria, thus enhancing the sterilization efficacy; furthermore, the biodegradation rate of the composition can be improved, and the possibility of environmental pollution after the composition is discharged into the environment is reduced.
Further, the emulsifier also comprises 5-8 parts by weight of polyoxyethylene cholesterol ether and 30-35 parts by weight of glycerol.
By adopting the technical scheme, the polyoxyethylene cholesterol ether and the glycerol are natural and nontoxic, the polyoxyethylene cholesterol ether and the glycerol can be well dissolved and uniformly dispersed in the disinfectant by compounding, the emulsion stability, the dispersion degree, the water retention property and the uniformity among the components are improved, a water-emulsion-oil three-phase interface is formed on the surface of small water drops formed by spraying the disinfectant and is coated on the surface of the disinfectant, the volatilization speed of the disinfectant is reduced, so that the disinfectant is fully contacted with bacteria, and the sterilization efficiency is improved.
Further, the sterilizing agent also comprises 455-465 parts of antifreeze agent, wherein the antifreeze agent comprises 30-50 parts of propylene glycol and 5-8 parts of ethanol.
By adopting the technical scheme, the propylene glycol and the ethanol are nontoxic and harmless, the synergistic property of the propylene glycol and the ethanol is mild, the volatility and the irritation can be reduced, the stability is improved, the propylene glycol and the ethanol are placed for 10 days under the conditions of high temperature of 60 ℃, high humidity and strong light irradiation, the appearance and the content are not obviously changed, the related substances are slightly increased, but still in the limit range, and the product is basically stable to the high temperature, the high humidity and the light. And the compatibility with other components is increased, the freezing point of the solution can be uniformly reduced, and the possibility that the sprayed composite solution is rapidly solidified at a low temperature so as to influence the sterilization effect is reduced.
Further, the composition also comprises 830-880 parts by weight of a neutralizing agent, wherein the neutralizing agent comprises the following components in parts by weight: 2.83 parts of anhydrous disodium hydrogen phosphate, 1.36 parts of potassium dihydrogen phosphate, 10 parts of tryptone, 3 parts of beef powder, 2 parts of glucose, 5 parts of sodium thiosulfate, 3 parts of lecithin, 3 parts of glycine, 0.03 part of tween and 1000 parts of distilled water.
Through adopting above-mentioned technical scheme, spray the germicide and disinfect after the disinfection and sterilization certain time, continue spraying the neutralizer, the neutralizer contacts with remaining germicide, can effectively neutralize the germicide, and can not bring other adverse reactions to the plant environment, reduce the influence of germicide residual to beasts and birds, and the influence of environment to the environment is discharged to the germicide, and environmental protection, safety more.
The second purpose of the invention is to provide a preparation method of the disinfectant for livestock and poultry cultivation, which has the advantages of simple preparation and use and higher safety.
In order to achieve the second object, the invention provides the following technical scheme: a preparation method of the disinfectant for livestock and poultry breeding comprises the following steps:
step one, preparing a solvent, an emulsifier and/or an antifreeze agent at normal temperature for later use;
and step two, adding dodecyl dimethyl benzyl ammonium bromide and garlic oil into a solvent according to the weight part ratio at the temperature of 30 ℃, uniformly stirring, and adding to obtain an emulsifier and/or an antifreeze sterilizing agent.
By adopting the technical scheme, the dodecyl dimethyl benzyl ammonium bromide and the garlic oil can be quickly and simply added into the solvent and uniformly mixed, so that the disinfectant which is high in sterilization efficiency, wide in antibacterial spectrum, safe and free of stimulation can be obtained, the operation is simple, the use is convenient, and the cost is reduced. The emulsifier can be directly added into the solvent to be uniformly mixed with the dodecyl dimethyl benzyl ammonium bromide and the garlic oil, so that the extraction rate of the effective sterilizing substances and the compatibility of each component are improved, and the sterilizing effect of the disinfectant is improved. The antifreeze agent is directly added into the solvent, the operation is simple, the application range of the disinfectant can be improved, and the possibility that the sterilization effect of the disinfectant is influenced by temperature and climate is reduced.
Further, the method comprises a third step of adding 2.83 parts by weight of anhydrous disodium hydrogen phosphate, 1.36 parts by weight of potassium dihydrogen phosphate, 10 parts by weight of tryptone, 3 parts by weight of beef powder, 2 parts by weight of glucose, 5 parts by weight of sodium thiosulfate, 3 parts by weight of lecithin, 3 parts by weight of glycine and 0.03 part by weight of tween into 1000 parts by weight of distilled water for complete dissolution, then adjusting the pH to 7.2-7.4, performing steam sterilization at 121 ℃ for 20min under pressure, and preparing a neutralizer to be placed in a refrigerator for later use.
Through adopting above-mentioned technical scheme, spray the germicide and disinfect after the disinfection and isolation certain time, take out the neutralizer and shake evenly, then spray the disinfection region, the neutralizer contacts with remaining germicide, can effectively neutralize the germicide, and can not bring other adverse reactions to the plant environment, reduce the influence that the germicide remained the beasts and birds, and the influence of germicide environment of discharging to the environment, and environmental protection, safety more.
In conclusion, the invention has the following beneficial effects:
1. the compound solution obtained by directly compounding the garlic oil and the dodecyl dimethyl benzyl ammonium bromide has no irritation and stronger antibacterial capability, can be directly sprayed to a farm in a spraying manner, is green and environment-friendly, convenient to operate and safer to use, has a certain anti-inflammatory effect, can obviously improve the nutrient environment of epidermal cells, increases the activity of epidermal cells, improves the color and the health of skin, can also improve the immunity of organisms by volatile components absorbed by animals, can play a certain deodorizing role, improves the use comfort level, is favorable for soothing the emotion of livestock and poultry, and reduces the influence on the livestock and poultry in the disinfection process;
2. the emulsifier can improve the surface tension among all component phases in the solution, improve the extraction degree, the dispersion uniformity and the material degradation rate of effective antibacterial components, reduce the possibility of environmental pollution after being discharged into the environment, and enable the surface of the disinfectant to form water-in-oil emulsified liquid which is easier to contact and combine with bacteria, thereby enhancing the sterilization effect;
3. the antifreeze can reduce the freezing point of the solution, reduce the possibility that the sprayed composite solution is quickly solidified at a lower temperature so as to influence the sterilization effect, reduce the volatility and the irritation and improve the stability;
4. the solvent compounded by the dimethylbenzene, the dimethyl sulfoxide and the dimethylformamide is nontoxic, has complementary advantages and is not easy to volatilize, the problem that the respiratory tract is stimulated by independently using the dimethylbenzene is solved, and meanwhile, sulfur dioxide released by the garlicin due to unstable properties and irritant gases released by other components can be absorbed, so that the stimulation to livestock and poultry is reduced, aromatic odor can be generated, the emotion of the livestock and poultry is further pacified, and the adverse effect on the livestock and poultry is reduced;
5. after spraying the germicide and disinfecting the sterilization for a certain time, continue to spray the neutralizer, the neutralizer contacts with remaining germicide, can effectively neutralize the germicide, and can not bring other adverse reactions to the plant environment, reduce the influence that the germicide remained to beasts and birds, and the influence of germicide environment of discharging to the environment, and environmental protection, safety more.
Detailed Description
The present invention will be described in further detail with reference to examples.
The specification and source information of the raw materials and components involved in the present invention are shown in table 1.
Table 1 specification and source information for raw materials and components
Figure BDA0002699715680000041
Figure BDA0002699715680000051
Preparation example
Adding 2.83 parts by weight of anhydrous disodium hydrogen phosphate, 1.36 parts by weight of potassium dihydrogen phosphate, 10 parts by weight of tryptone, 3 parts by weight of beef powder, 2 parts by weight of glucose, 5 parts by weight of sodium thiosulfate, 3 parts by weight of lecithin, 3 parts by weight of glycine and 0.03 part by weight of tween into 1000 parts by weight of distilled water for complete dissolution, then adjusting the pH to 7.2-7.4 by using 3% of sodium hydroxide and 5% of hydrochloric acid, performing pressure steam sterilization at 121 ℃ for 20min, preparing a neutralizer, and placing the neutralizer in a refrigerator for later use.
Examples
The components and proportions in the examples are shown in table 2:
TABLE 2 Components and proportions of the examples
Figure BDA0002699715680000052
Figure BDA0002699715680000061
The preparation method of the above example is as follows:
examples 1 to 4
A preparation method of the disinfectant for livestock and poultry breeding comprises the following steps:
step one, according to the mixture ratio of table 2, uniformly mixing xylene, dimethyl sulfoxide and dimethylformamide according to the mixture ratio at normal temperature to obtain a solvent for later use;
and step two, adding dodecyl dimethyl benzyl ammonium bromide and garlic oil into the solvent according to the weight part ratio at the temperature of 30 ℃, and uniformly stirring to obtain the disinfectant for livestock and poultry breeding.
Examples 5 to 9
The preparation method of the disinfectant for livestock and poultry breeding is different from the embodiment 1 in that:
step one, uniformly mixing dimethylbenzene, dimethyl sulfoxide and dimethylformamide according to the proportion at normal temperature to obtain a solvent for later use, and uniformly mixing polyoxyethylene sorbitan monooleate, alkylphenol polyoxyethylene, polyoxyethylene cholesterol ether and glycerol to obtain an emulsifier for later use;
and step two, adding dodecyl dimethyl benzyl ammonium bromide and garlic oil into a solvent according to the weight part ratio at the temperature of 30 ℃, adding an emulsifier, and uniformly stirring to obtain the disinfectant for livestock and poultry breeding.
Examples 10 to 12
The preparation method of the disinfectant for livestock and poultry breeding is different from the embodiment 1 in that:
step one, uniformly mixing dimethylbenzene, dimethyl sulfoxide and dimethylformamide according to the proportion at normal temperature to obtain a solvent for later use, uniformly mixing polyoxyethylene sorbitan monooleate, alkylphenol polyoxyethylene, polyoxyethylene cholesterol ether and glycerol to obtain an emulsifier for later use, and then uniformly mixing propylene glycol and ethanol according to the weight ratio to obtain an antifreeze agent for later use;
and step two, adding dodecyl dimethyl benzyl ammonium bromide and garlic oil into a solvent according to the weight part ratio at the temperature of 30 ℃, sequentially adding an emulsifier and an antifreeze, and uniformly stirring to obtain the disinfectant for livestock and poultry breeding.
Examples 13 to 14
The preparation method of the disinfectant for livestock and poultry breeding is different from the embodiment 1 in that: and step three, after the disinfectant obtained in the step two is used for spraying sterilization, taking out the neutralizer prepared in the preparation example, shaking up, spraying the neutralizer to a disinfection area, contacting with the disinfectant, and neutralizing the residual disinfectant.
The components and proportions in the examples are shown in table 3:
TABLE 3 Components and proportions of the examples
Figure BDA0002699715680000071
Performance testing
Test method
The performance test methods for the disinfectants prepared in the above examples and comparative examples are as follows:
1. sterilization performance: at normal temperature, the sterilization rate of the disinfectant within 5mim after being diluted by 500 times is tested according to technical specification for identifying disinfectant for animals (1992) No. 101 of agricultural (herdsmedicine);
2. stability: the sterilization rate of the disinfectant of different examples to bacteria within 5 mm after being diluted by 500 times is tested according to technical specification for identifying disinfectant for animals (1992) No. 101 of agricultural (herdsmedicine) word at 0 ℃ and 60 ℃ respectively;
3、SO2volatilization amount: the SO of the disinfectants in different examples is determined according to 'determination of formaldehyde absorption-pararosaniline spectrophotometry' of HJ482-2009 environmental air sulfur dioxide2And (4) volatilization amount.
Test results
The performance test results of the aerogel textile fabric prepared in the above examples are shown in table 4:
table 4 results of performance test of aerogel textile fabrics prepared in each example
Figure BDA0002699715680000081
Figure BDA0002699715680000091
The results of the performance tests of the disinfectants prepared in the above respective proportions are shown in table 5:
table 5 disinfectant performance test results of aerogel textile fabrics prepared according to various proportions
Figure BDA0002699715680000092
Figure BDA0002699715680000101
From the above data it can be seen that:
1. as can be seen from comparison of comparative examples 1-2 with example 1, the synergistic effect of dodecyl dimethyl benzyl ammonium bromide and garlic oil greatly promotes the bactericidal rate and improves the antibacterial spectrum compared with the single use.
2. Compared with the example 1, the weight ratio of the dodecyl dimethyl benzyl ammonium bromide to the garlic oil has an influence on the sterilization rate of the disinfectant, and the dodecyl dimethyl benzyl ammonium bromide has an increased specific gravity within a certain range and plays a role in promoting the sterilization rate.
3. As can be seen from the comparison of example 3 with example 1, the increase in the weight ratio of the solvent contributes to the promotion of the sterilization rate of the disinfectant and to the extent of the improvement in the stability of the disinfectant, the reduction in the variation of the sterilization rate of the disinfectant at 60 ℃ and 0 ℃, and, in addition, the reduction in the SO ratio2Increased absorption and reduced SO2Detected value, SO of example2All values of (A) are less than the detection limit of the standard method of 0.004mg/m3And meets the standard.
4. In example 4, compared with example 1, the solvent has different weight ratios of the components, so that the bactericidal performance of the disinfectant is changed, and therefore, the components in the solvent have a synergistic effect, and the proportion can improve the bactericidal rate of the disinfectant within a certain range.
5. As can be seen from example 5 compared with example 1, the bactericidal rate of the disinfectant is increased when the emulsifier is added, and the emulsifier can enable the disinfectant solution to form emulsified liquid of 'water-in-oil' type, and the microstructure is easier to contact and combine with bacteria, thereby enhancing the sterilization effect; as can be seen from example 6 compared with example 1, as the moving range of the emulsifier increases, the acceleration of bactericidal activity is positively correlated.
6. As can be seen from the comparison between example 7 and example 5, when the specific gravities of the components of the emulsifier are changed, the bactericidal performance of the disinfectant is also changed, and therefore, the components of the emulsifier are coordinated and matched, and the combined use plays a role in promoting the bactericidal rate of the disinfectant within a certain range.
7. Compared with the example 5, the comparison of the example 8 with the example 5 shows that when the components in the emulsifier further comprise polyoxyethylene cholesterol ether and glycerol, and the comparison of the example 9 with the example 7 shows that the change of the weight ratio of the polyoxyethylene cholesterol ether and the glycerol in the emulsifier changes the sterilization rate of the disinfectant, the disinfectant can act together with the polyoxyethylene sorbitan monooleate and the alkylphenol polyoxyethylene ether in the emulsifier, the surface of small water beads formed by spraying the disinfectant forms a water-emulsion-oil three-phase interface, the surface of the disinfectant is coated with the surface of the disinfectant, the volatilization speed of the disinfectant is reduced, so that the disinfectant is fully contacted with bacteria, and the sterilization efficiency is improved.
8. Compared with the example 1, the example 10 shows that after the antifreeze agent is added into the disinfectant, the stability of the disinfectant at the temperature of (0 ℃ -60 ℃) is increased, and particularly the change is smaller at low temperature, so that the stability of the disinfectant can be improved by compounding the antifreeze agent and the solvent; in comparison with example 10, it can be seen that the antifreeze agent weight ratio has an effect on the stability of the disinfectant when it is varied within a certain range. 9. In that respect
10. Compared with the example 10, the example 12 shows that when the specific gravities of the components in the antifreeze agent are different, the stability and the sterilization rate of the disinfectant are affected, and the components of the antifreeze agent have a synergistic effect, so that the stability and the sterilization rate of the disinfectant can be promoted.
11. Compared with the embodiment 12, the embodiment 13 shows that after the neutralizing agent is added into the disinfectant, the bactericidal performance of the disinfectant basically disappears, and the neutralizing agent is in contact with the residual bactericidal agent, so that the bactericidal agent can be effectively neutralized, other adverse reactions to the environment of a farm can not be caused, the influence of the residual bactericidal agent on livestock and poultry and the influence of the bactericide discharged into the environment on the environment can be reduced, and the disinfectant is more environment-friendly and safer; as can be seen from comparison of example 14 with example 13, increasing the amount of neutralizing agent within a certain range increases the neutralizing effect of the bactericide.
The present embodiment is only for explaining the present invention, and it is not limited to the present invention, and those skilled in the art can make modifications of the present embodiment without inventive contribution as needed after reading the present specification, but all of them are protected by patent law within the scope of the claims of the present invention.

Claims (8)

1. The disinfectant for livestock and poultry breeding is characterized by comprising a sterilizing agent, wherein the sterilizing agent comprises the following components in parts by weight: 165 parts of dodecyl dimethyl benzyl ammonium bromide, 165 parts of garlic oil and 1150 parts of solvent.
2. The disinfectant for livestock and poultry breeding according to claim 1, wherein the solvent comprises the following components in parts by weight: 18-25 parts of dimethylbenzene, 70-80 parts of dimethyl sulfoxide and 35-50 parts of dimethylformamide.
3. The disinfectant for livestock and poultry breeding as recited in claim 2, wherein said disinfectant further comprises 830-845 parts of an emulsifier, wherein the emulsifier comprises 25-30 parts of polyoxyethylene sorbitan monooleate and 50-65 parts of alkylphenol ethoxylates.
4. The disinfectant for livestock and poultry breeding according to claim 3, wherein the emulsifier further comprises 5-8 parts by weight of polyoxyethylene cholesterol ether and 30-35 parts by weight of glycerol.
5. The disinfectant for livestock and poultry breeding according to any one of claims 1 to 4, wherein the disinfectant further comprises 455-465 parts of an antifreeze agent, and the antifreeze agent comprises 30-50 parts by weight of propylene glycol and 5-8 parts by weight of ethanol.
6. The disinfectant for livestock breeding as recited in claim 5, wherein said composition further comprises 830-880 parts by weight of a neutralizing agent, the neutralizing agent comprises the following components in parts by weight: 2.83 parts of anhydrous disodium hydrogen phosphate, 1.36 parts of potassium dihydrogen phosphate, 10 parts of tryptone, 3 parts of beef powder, 2 parts of glucose, 5 parts of sodium thiosulfate, 3 parts of lecithin, 3 parts of glycine, 0.03 part of tween and 1000 parts of distilled water.
7. The preparation method of the disinfectant for livestock and poultry breeding according to claim 6, characterized by comprising the following steps:
step one, preparing a solvent, an emulsifier and/or an antifreeze agent at normal temperature for later use;
and step two, adding dodecyl dimethyl benzyl ammonium bromide and garlic oil into a solvent according to the weight part ratio at the temperature of 30 ℃, uniformly stirring, and adding to obtain an emulsifier and/or an antifreeze sterilizing agent.
8. The preparation method of the disinfectant for livestock and poultry breeding according to claim 7, characterized by further comprising a third step of adding 2.83 parts by weight of anhydrous disodium hydrogen phosphate, 1.36 parts by weight of monopotassium phosphate, 10 parts by weight of tryptone, 3 parts by weight of beef powder, 2 parts by weight of glucose, 5 parts by weight of sodium thiosulfate, 3 parts by weight of lecithin, 3 parts by weight of glycine and 0.03 part by weight of tween into 1000 parts by weight of distilled water for complete dissolution, then adjusting the pH to 7.2-7.4, performing steam sterilization at 121 ℃ under pressure for 20min, and preparing a neutralizer to be placed in a refrigerator for later use.
CN202011017941.8A 2020-09-24 2020-09-24 Disinfectant for livestock and poultry breeding and preparation method thereof Pending CN114246194A (en)

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