CN114129670A - Aquilaria sinensis sleep-aiding herbal atomized composition and preparation method and application thereof - Google Patents

Aquilaria sinensis sleep-aiding herbal atomized composition and preparation method and application thereof Download PDF

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CN114129670A
CN114129670A CN202210006492.XA CN202210006492A CN114129670A CN 114129670 A CN114129670 A CN 114129670A CN 202210006492 A CN202210006492 A CN 202210006492A CN 114129670 A CN114129670 A CN 114129670A
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parts
powder
agilawood
sleep
herbal
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杨继广
杨占文
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Qihuang Treasure Beijing Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/83Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • A61K36/835Aquilaria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/074Ganoderma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8988Gastrodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Abstract

The invention belongs to the technical field of Chinese herbal medicine atomized products, and discloses a Chinese eaglewood sleep-aiding herbal atomized composition and a preparation method and application thereof. The composition is prepared from pure plant Chinese herbal medicines. The medicine mainly takes sweet taste, neutral nature, spleen, lung, stomach and kidney meridians as the medicine channels. The lucid ganoderma has the effects of tonifying qi and soothing nerves; gastrodia elata has the effect of calming liver-yang; flos Caryophylli has effects of warming middle-jiao and tonifying yang; dark plum fruit has the effects of astringing lung and relieving cough; hyacinth dolichos flower has the functions of strengthening spleen and stomach; the jujube kernel can nourish heart and calm mind; the bunge cherry seeds can expel qi and promote urination; herba Moslae can resolve dampness and regulate the middle warmer; rhizoma Polygonati has effects of invigorating spleen and replenishing qi; american ginseng tonifies qi and nourishes yin. The above formula is an integral formula, and after compatibility, the formula is helpful for soothing the nerves, helping sleep, nourishing the heart, benefiting the liver, tonifying qi, nourishing yin, warming the middle-jiao and eliminating dampness. The preparation method reduces the loss of effective components, avoids the influence on the effective components in the raw material treatment, and is easy to store the extract. The distillation can purify the effective components in the extract again, so as to ensure the quality of the product, the purification process also has the sterilization effect, and the use fragrance of the composition is improved.

Description

Aquilaria sinensis sleep-aiding herbal atomized composition and preparation method and application thereof
Technical Field
The invention belongs to the technical field of Chinese herbal medicine atomization products, and particularly relates to an agilawood sleep-aiding herbal atomization composition and a preparation method and application thereof.
Background
In the current situation of the current commercial society, social workers under a modern working mechanism are under high-intensity and overload mental pressure and living pressure, the working time is as long as more than ten hours every day, the social workers sit on the internet in front of a computer screen to work, and in addition, the quick-paced life of the modern working mechanism is long, so that many caregivers are in poor immune function at a low age, the working and living pressure of many workers is extremely high, the workers cannot sleep easily, the working efficiency of the workers in the next day is low, and even the conditions of sub-health or depression are very common.
There are many products on the market today to alleviate sleep anxiety or aid sleep. The latex pillow is used, and the product enables the body to relax and further enter a sleep state in a mode consistent with the human engineering and physical design. But this approach is a physical approach which still requires the patient to make adjustments on their own. And various sleep-aiding mattresses, sleep-aiding lamps and the like can not completely relieve the problem of difficult sleep.
Most of the western medicines for helping sleep are finished medicines, such as sleeping pills, tranquilization pills and other western medicines, and a large number of health care products are sold.
The related technology discloses a medicine prepared by combining ganoderma lucidum, chrysanthemum, rose, cassia seed, silkworm excrement and jujube kernel, the medicine is powdery and belongs to aromatic mixed medicine, the use mode is that the medicine is adsorbed on product fur and absorbed by nasal mucosa, the formula of the medicine is too simple, and the administration mode easily causes nasal irritation of a user, so that the medicine is inconvenient to use and has low absorption efficiency.
The related technology discloses a solid aromatic sleep aid, which is prepared from sleep aid essence, solid air freshening glue, a high-efficiency solubilizer and a preservative, wherein the sleep aid essence comprises cananga oil, eucalyptus essential oil, jasmine essential oil, roman chamomile essential oil, coriander seed oil, nardostachys chinensis essential oil, lavender oil, rose oil, clove oil, patchouli oil, sage oil, juniper oil, a mixture of an antioxidant and dipropylene glycol. Not only the raw materials contain a plurality of chemical components, but also the preparation method is very complicated.
The related technology discloses a nerve-soothing and sleep-aiding medicine, which is prepared from raw materials of gamma-aminobutyric acid, dendrobium officinale dry powder, sialic acid, xanthan gum, ethyl cellulose and hydroxypropyl cellulose. The preparation method is a tablet obtained by hot melting treatment. The medicine is convenient to use, but mainly depends on gamma-aminobutyric acid to act, and has inhibitory neurotransmitter and sedative effects.
At present, a plurality of essential oils for soothing the nerves and helping sleep are adopted, and the effect is poor due to the adoption of a single plant extract.
Disclosure of Invention
In order to solve the problems in the prior art, the invention aims to provide an agilawood sleep-aiding herbal atomized composition and a preparation method and application thereof.
The technical scheme adopted by the invention is as follows: the agilawood sleep-aiding herbal atomized composition is mainly prepared from the following raw materials in parts by mass:
70-100 parts of agilawood, 6-12 parts of lucid ganoderma, 3-10 parts of gastrodia elata, 6-15 parts of clove, 3-10 parts of dark plum, 8-15 parts of white hyacinth bean flower, 6-15 parts of jujube kernel, 3-10 parts of bunge cherry seed, 3-9 parts of elsholtzia, 10-15 parts of rhizoma polygonati and 3-6 parts of American ginseng.
Agilawood and the name of the traditional Chinese medicine. Is resin-containing wood derived from Aquilaria agallocha Roxb. and Aquilaria sinensis (Lour.) Gilg of Aquilaria of Thymelaeaceae. Has effects of activating qi-flowing, relieving pain, warming middle-jiao, relieving vomit, and absorbing qi and relieving asthma. It can be used for treating chest and abdomen distention and pain due to cold accumulation and qi stagnation, stomach cold emesis, and asthma due to kidney deficiency. Pungent and bitter taste, slightly warm in nature; it enters spleen, stomach and kidney meridians.
Ganoderma lucidum and Chinese medicine name. Is dried fruiting body of Ganoderma lucidum (Leys. ex Fr.) karst or Ganoderma sinense Zhao, Xu et Zhang of Ganoderma of Polyporaceae. Has effects of invigorating qi, tranquilizing mind, relieving cough and asthma. It can be used for treating restlessness of heart-mind, insomnia, palpitation due to fright, cough, asthma, excessive phlegm, and asthenia. Sweet in taste and neutral in nature; it enters heart, lung, liver and kidney meridians.
Gastrodia elata, name of traditional Chinese medicine. Is dried tuber of Gastrodia elata Bl. of Gastrodia of Orchidaceae. Has effects of calming endogenous wind, relieving spasm, suppressing liver yang, dispelling pathogenic wind, and dredging collaterals. It can be used for treating stirring of liver-wind, convulsive epilepsy, convulsion, vertigo, headache, numbness of limbs, hemiplegia, and rheumatalgia. Sweet in taste and neutral in nature; it enters liver meridian.
Clove, name of traditional Chinese medicine. Is dried bud of Eugenia caryophyllata Thunb of Eugenia of Myrtaceae. Has the effects of warming the middle-jiao, lowering the adverse flow of qi, warming the kidney and tonifying yang. It can be used for treating singultus due to stomach cold, abdominal psychroalgia, anorexia, vomiting, diarrhea, kidney deficiency, sexual impotence, soreness of waist and knees, and dorsal furuncle. Pungent taste and warm nature; it enters spleen, stomach and kidney meridians.
Dark plum, name of traditional Chinese medicine. Is a near-mature fruit of Prunus mume (Sieb.) of Prunus of Rosaceae. Has effects of astringing lung, relieving cough, relieving diarrhea with astringents, relieving ascaris, relieving pain, promoting fluid production, and quenching thirst. It can be used for treating chronic cough, chronic diarrhea, chronic dysentery, abdominal pain due to ascariasis, emesis, and diabetes due to deficiency heat. Sour, astringent and neutral in flavor; it enters liver, spleen, lung and large intestine meridians.
Dolichos lablab flower is bean hyacinth bean, is collected in 7-8 months and dried in the sun or in the shade. Zhejiang, Anhui and Henan provinces. Strengthen spleen and stomach, relieve summer heat and resolve dampness. It is indicated for dysentery, diarrhea, leucorrhea with reddish discharge. Mild in nature, sweet and light in taste, and non-toxic. Strengthen spleen and stomach, relieve summer heat and resolve dampness. It is indicated for dysentery, diarrhea, leucorrhea with reddish discharge.
Jujube kernel, name of traditional Chinese medicine. Is mature seed of Ziziphus jujuba Mill.var. spinosa (Bunge) Hu ex H.F.Chou belonging to Ziziphus of Rhamnaceae. Has the effects of nourishing heart, benefiting liver, tranquilizing, and arresting sweating. It is mainly used for treating blood deficiency palpitation, severe palpitation, amnesia, insomnia, dreaminess, vertigo, body deficiency spontaneous perspiration, night sweat, body fluid consumption, thirst, and dry throat. Sweet and sour in taste, mild in nature and warm in nature; it enters heart, liver and gallbladder meridians.
Bunge cherry seed, the name of traditional Chinese medicine. Is seed of Prunus humilis Bunge, Prunus japonica Thunb, Prunus japonica Lindl, Prunus ulmaria Bungriffith Lindl, and Prunus pedunculata Maxim of Prunus of Rosaceae. Has effects of loosening bowel to relieve constipation, descending qi, promoting urination and relieving swelling. It can be used for treating constipation due to intestinal dryness, edema, and edema of loempe. Pungent, bitter, sweet and neutral in flavor; it enters spleen, large and small intestine meridians.
Herba Moslae, the name of Chinese medicine. Is aerial part of Moslachinensis Maxim. or Moslachinensis Jiangxiangru of Moslashinensis of Moslangshima of Labiatae. The former is called green Chinese mosla herb, the latter is called Jiangxiang Chinese mosla herb. Has the effects of inducing sweat, relieving exterior syndrome, eliminating dampness, regulating the middle warmer, inducing diuresis and relieving edema. It can be used for treating wind-cold type common cold, edema and loempe. Pungent taste and mild nature; it enters lung, spleen and stomach meridians.
Rhizoma Polygonati, name of Chinese medicine. Is dried rhizome of Polygonatum sibiricum Red, Polygonatum cyrtonema Hua or Polygonatum kingianum Coll. et Hemsl. Has effects of nourishing yin, moistening lung, invigorating spleen, invigorating qi, replenishing kidney essence, and replenishing essence. Mainly treats yin deficiency cough, cough ouch due to lung dryness, spleen deficiency and hypodynamia, poor appetite and dry mouth and diabetes; kidney deficiency, soreness and weakness of waist and knees, impotence, spermatorrhea, tinnitus, dim eyesight, premature graying of hair, asthenia, emaciation, and tinea. Sweet in taste and neutral in nature; it enters spleen, lung and kidney meridians.
American ginseng, name of traditional Chinese medicine. Is root of Panax quinquefolium L. of Panax of Araliaceae. Has the effects of invigorating qi, nourishing yin, clearing away heat, and promoting fluid production. It is mainly indicated for syndrome of both qi and yin deficiency, syndrome of lung qi deficiency and lung yin deficiency, thirst due to deficiency of body fluid due to deficiency of heat disease, and diabetes. Sweet, slightly bitter and cool in nature; it enters lung, heart and kidney meridians.
Preferably, the composition is mainly prepared from the following raw materials in parts by mass:
80-90 parts of agilawood, 8-10 parts of lucid ganoderma, 5-9 parts of gastrodia elata, 8-13 parts of clove, 5-9 parts of dark plum, 9-13 parts of white hyacinth bean flower, 8-13 parts of jujube kernel, 5-9 parts of bunge cherry seed, 5-8 parts of elsholtzia, 11-14 parts of rhizoma polygonati and 4-5 parts of American ginseng.
Preferably, the composition is mainly prepared from the following raw materials in parts by mass:
85 parts of agilawood, 9 parts of lucid ganoderma, 7 parts of gastrodia elata, 10 parts of clove, 7 parts of dark plum fruit, 11 parts of white hyacinth bean flower, 10 parts of jujube kernel, 7 parts of bunge cherry seed, 6 parts of elsholtzia, 12 parts of rhizoma polygonati and 4.5 parts of American ginseng.
A preparation method of an agilawood sleep-aiding herbal atomized composition comprises the following steps:
respectively selecting agilawood, lucid ganoderma, tall gastrodia tuber, clove, dark plum, white hyacinth bean flower, jujube kernel, bunge cherry seed, elsholtzia, manyflower solomonseal rhizome and American ginseng according to corresponding proportions, drying, crushing and grinding to obtain standby materials of agilawood powder, lucid ganoderma powder, tall gastrodia tuber powder, clove powder, dark plum powder, white hyacinth bean pollen, jujube kernel powder, bunge cherry seed powder, elsholtzia powder, fine yellow powder and American ginseng powder, uniformly mixing, and adding a solvent to obtain an extract;
distilling the obtained extract, standing for layering, and separating water and oil to obtain lignum Aquilariae Resinatum sleep-promoting herbal atomized composition product.
And after standing and layering, separating water and oil by adopting a centrifugal method, and removing water to obtain a finished product of the sleep-aiding Chinese eaglewood herb atomized composition.
Preferably, agilawood, lucid ganoderma, gastrodia elata, clove, dark plum, white hyacinth bean flower, jujube kernel, bunge cherry seed, elsholtzia, rhizoma polygonati and American ginseng are selected, and the drying temperature is 50-60 ℃ during drying.
Preferably, the drying time is 10 to 30 minutes.
Preferably, the standby materials of the agilawood powder, the ganoderma lucidum powder, the gastrodia elata powder, the clove powder, the dark plum powder, the white hyacinth bean pollen, the date kernel powder, the bunge cherry seed powder, the elsholtzia powder, the fine yellow powder and the American ginseng powder are obtained, and the particle sizes of the standby materials are all 150-mesh and 280-mesh filter sieves.
Preferably, the solvent comprises 65-75 wt% ethanol.
Preferably, the volume ratio of the total mass of the standby agilawood powder, the ganoderma lucidum powder, the gastrodia elata powder, the clove powder, the dark plum powder, the white hyacinth bean powder, the date kernel powder, the bunge cherry seed powder, the elsholtzia powder, the fine yellow powder and the American ginseng powder to the solvent is 100 g: 10-20 mL.
Use of an aromatic sleep-aiding herbal atomized composition, prepared according to any one of claims 4 to 9, in atomizing essential oil products.
The invention has the beneficial effects that:
the invention provides a Chinese eaglewood sleep-aiding herbal atomized composition which is prepared from pure plant Chinese herbal medicines.
The composition mainly takes sweet taste, neutral nature, spleen, lung, stomach and kidney meridians as the medicine channels. The lucid ganoderma has the effects of tonifying qi, soothing nerves, and relieving cough and asthma; gastrodia elata has the effects of calming endogenous wind and relieving spasm, calming liver-yang, dispelling wind and dredging collaterals; clove, flos Caryophylli, for warming the middle-jiao to lower adverse flow, warming the kidney to strengthen yang; dark plum, astringing lung to relieve cough, relieving diarrhea with astringents, relieving ascaris to relieve pain, promoting the production of body fluid to quench thirst; the hyacinth dolichos flower has the effects of strengthening the spleen and stomach, relieving summer heat and eliminating dampness; the jujube kernel has the effects of nourishing heart, benefiting liver, soothing nerves and arresting sweating; semen Pruni has effects of loosening bowel to relieve constipation, descending qi, promoting urination and relieving swelling; herba Moslae, inducing sweat to relieve exterior syndrome, eliminating dampness and regulating the middle warmer, inducing diuresis to alleviate edema; rhizoma Polygonati has effects of nourishing yin, moistening lung, invigorating spleen, invigorating qi, replenishing kidney essence; american ginseng has the effects of tonifying qi, nourishing yin, clearing heat and promoting fluid production. The above formulas are integrated, and the combination of the formulas is helpful for tranquilizing mind, improving sleep, nourishing heart, benefiting liver, invigorating qi, nourishing yin, warming spleen and stomach, and eliminating dampness.
In the preparation process of the composition, the raw materials are dried, ground and crushed, and then the extract is mixed and purified to obtain the essential oil product, so that the loss of active ingredients in the raw materials is reduced, the influence on the active ingredients in the raw material treatment process in the initial stage is avoided, and the extract is easy to store. And then, the effective components in the extract are further purified again in a distillation mode, so that the quality of the final product is effectively ensured, a certain sterilization effect is achieved in the purification process, and the use fragrance is improved.
Detailed Description
The present invention is further illustrated below with reference to specific examples. It will be appreciated by those skilled in the art that the following examples, which are set forth to illustrate the present invention, are intended to be part of the present invention, but not to be construed as limiting the scope of the present invention. The reagents used are all conventional products which are commercially available.
Example 1:
a preparation method of an agilawood sleep-aiding herbal atomized composition comprises the following steps:
respectively selecting 70 g of agilawood, 60 g of lucid ganoderma, 30 g of gastrodia elata, 60 g of clove, 30 g of dark plum, 80 g of white hyacinth bean flower, 60 g of date kernel, 30 g of bunge cherry seed, 30 g of elsholtzia, 100g of rhizoma polygonati and 30 g of American ginseng according to corresponding proportions, drying at 50 ℃ for 10 minutes, crushing and grinding, and screening by a 150-mesh filter screen to obtain standby materials of agilawood powder, lucid ganoderma powder, gastrodia elata powder, clove powder, dark plum powder, white hyacinth bean pollen, date kernel powder, bunge cherry seed powder, elsholtzia powder, fine yellow powder and American ginseng powder, uniformly mixing, and adding 58 g of 65 wt% ethanol to obtain an extract;
distilling the obtained extract, standing for layering, and separating water and oil to obtain lignum Aquilariae Resinatum sleep-promoting herbal atomized composition product.
And after standing and layering, separating water and oil by adopting a centrifugal method, and removing water to obtain a finished product of the sleep-aiding Chinese eaglewood herb atomized composition.
Example 2:
a preparation method of an agilawood sleep-aiding herbal atomized composition comprises the following steps:
respectively selecting 100g of agilawood, 120 g of lucid ganoderma, 100g of gastrodia elata, 150 g of clove, 100g of dark plum fruit, 150 g of white hyacinth bean flower, 150 g of date seed, 100g of bunge cherry seed, 90 g of elsholtzia, 150 g of rhizoma polygonati and 60 g of American ginseng according to corresponding proportions, drying at 60 ℃ for 30 minutes, crushing and grinding, and screening by a 280-mesh filter screen to obtain standby materials of agilawood powder, lucid ganoderma powder, gastrodia elata powder, clove powder, dark plum fruit powder, white hyacinth bean pollen, date seed powder, bunge cherry seed powder, elsholtzia powder, fine yellow powder and American ginseng powder, uniformly mixing, and adding 254 g of 75 wt% ethanol to obtain an extract;
distilling the obtained extract, standing for layering, and separating water and oil to obtain lignum Aquilariae Resinatum sleep-promoting herbal atomized composition product.
And after standing and layering, separating water and oil by adopting a centrifugal method, and removing water to obtain a finished product of the sleep-aiding Chinese eaglewood herb atomized composition.
Example 3:
a preparation method of an agilawood sleep-aiding herbal atomized composition comprises the following steps:
respectively selecting 80 g of agilawood, 80 g of lucid ganoderma, 50 g of gastrodia elata, 80 g of clove, 50 g of dark plum fruit, 90 g of white hyacinth bean flower, 80 g of date seed, 50 g of bunge cherry seed, 50 g of elsholtzia, 110 g of rhizoma polygonati and 40 g of American ginseng according to corresponding proportions, drying at 50 ℃ for 30 minutes, crushing and grinding, and screening by a 280-mesh filter screen to obtain standby materials of agilawood powder, lucid ganoderma powder, gastrodia elata powder, clove powder, dark plum fruit powder, white hyacinth bean pollen, date seed powder, bunge cherry seed powder, elsholtzia powder, fine yellow powder and American ginseng powder, uniformly mixing, and adding 76 g of 65 wt% ethanol to obtain an extract;
distilling the obtained extract, standing for layering, and separating water and oil to obtain lignum Aquilariae Resinatum sleep-promoting herbal atomized composition product.
And after standing and layering, separating water and oil by adopting a centrifugal method, and removing water to obtain a finished product of the sleep-aiding Chinese eaglewood herb atomized composition.
Example 4:
a preparation method of an agilawood sleep-aiding herbal atomized composition comprises the following steps:
respectively selecting 90 g of agilawood, 100g of lucid ganoderma, 90 g of gastrodia elata, 130 g of clove, 90 g of dark plum, 130 g of white hyacinth bean flower, 130 g of date kernel, 90 g of bunge cherry seed, 80 g of elsholtzia, 140 g of rhizoma polygonati and 50 g of American ginseng according to corresponding proportions, drying at 60 ℃ for 10 minutes, crushing and grinding, and screening by a 150-mesh filter screen to obtain standby materials of agilawood powder, lucid ganoderma powder, gastrodia elata powder, clove powder, dark plum powder, white hyacinth bean pollen, date kernel powder, bunge cherry seed powder, elsholtzia powder, fine yellow powder and American ginseng powder, uniformly mixing, and adding 224 g of 65 wt% ethanol to obtain an extract;
distilling the obtained extract, standing for layering, and separating water and oil to obtain lignum Aquilariae Resinatum sleep-promoting herbal atomized composition product.
And after standing and layering, separating water and oil by adopting a centrifugal method, and removing water to obtain a finished product of the sleep-aiding Chinese eaglewood herb atomized composition.
Example 5:
a preparation method of an agilawood sleep-aiding herbal atomized composition comprises the following steps:
respectively selecting 85 g of agilawood, 90 g of lucid ganoderma, 70 g of gastrodia elata, 100g of clove, 70 g of dark plum, 110 g of white hyacinth bean flower, 100g of date kernel, 70 g of bunge cherry seed, 60 g of elsholtzia, 120 g of rhizoma polygonati and 45 g of American ginseng according to corresponding proportions, drying at 60 ℃ for 10 minutes, crushing and grinding, and screening by a 150-mesh filter screen to obtain standby materials of agilawood powder, lucid ganoderma powder, gastrodia elata powder, clove powder, dark plum powder, white hyacinth bean pollen, date kernel powder, bunge cherry seed powder, elsholtzia powder, fine yellow powder and American ginseng powder, uniformly mixing, and adding 184 g of 75 wt% ethanol to obtain an extract;
distilling the obtained extract, standing for layering, and separating water and oil to obtain lignum Aquilariae Resinatum sleep-promoting herbal atomized composition product.
And after standing and layering, separating water and oil by adopting a centrifugal method, and removing water to obtain a finished product of the sleep-aiding Chinese eaglewood herb atomized composition.
The using method comprises the following steps: can be applied by adding into a daily atomizer.
The present invention is not limited to the above alternative embodiments, and any other products in various forms can be obtained by the present invention, and the present invention is within the protection scope of the present invention. The above embodiments should not be construed as limiting the scope of the present invention, and it will be understood by those skilled in the art that modifications may be made to the technical solutions described in the above embodiments, or equivalent substitutions may be made to some or all of the technical features thereof, without departing from the scope of the present invention, and at the same time, such modifications or substitutions may not make the essence of the corresponding technical solutions depart from the scope of the embodiments of the present invention.

Claims (10)

1. The sleep-aiding agilawood herb atomized composition is characterized by being prepared from the following raw materials in parts by mass:
70-100 parts of agilawood, 6-12 parts of lucid ganoderma, 3-10 parts of gastrodia elata, 6-15 parts of clove, 3-10 parts of dark plum, 8-15 parts of white hyacinth bean flower, 6-15 parts of jujube kernel, 3-10 parts of bunge cherry seed, 3-9 parts of elsholtzia, 10-15 parts of rhizoma polygonati and 3-6 parts of American ginseng.
2. The agilawood sleep-aiding herbal atomized composition according to claim 1, wherein the composition is mainly prepared from the following raw materials in parts by mass:
80-90 parts of agilawood, 8-10 parts of lucid ganoderma, 5-9 parts of gastrodia elata, 8-13 parts of clove, 5-9 parts of dark plum, 9-13 parts of white hyacinth bean flower, 8-13 parts of jujube kernel, 5-9 parts of bunge cherry seed, 5-8 parts of elsholtzia, 11-14 parts of rhizoma polygonati and 4-5 parts of American ginseng.
3. The agilawood sleep-aiding herbal atomized composition according to claim 2, wherein the composition is mainly prepared from the following raw materials in parts by mass:
85 parts of agilawood, 9 parts of lucid ganoderma, 7 parts of gastrodia elata, 10 parts of clove, 7 parts of dark plum fruit, 11 parts of white hyacinth bean flower, 10 parts of jujube kernel, 7 parts of bunge cherry seed, 6 parts of elsholtzia, 12 parts of rhizoma polygonati and 4.5 parts of American ginseng.
4. A process for the preparation of a sleep aid herbal aerosolized composition according to any one of claims 1 to 3, said process comprising the steps of:
respectively selecting agilawood, lucid ganoderma, tall gastrodia tuber, clove, dark plum, white hyacinth bean flower, jujube kernel, bunge cherry seed, elsholtzia, manyflower solomonseal rhizome and American ginseng according to corresponding proportions, drying, crushing and grinding to obtain standby materials of agilawood powder, lucid ganoderma powder, tall gastrodia tuber powder, clove powder, dark plum powder, white hyacinth bean pollen, jujube kernel powder, bunge cherry seed powder, elsholtzia powder, fine yellow powder and American ginseng powder, uniformly mixing, and adding a solvent to obtain an extract;
distilling the obtained extract, standing for layering, and separating water and oil to obtain lignum Aquilariae Resinatum sleep-promoting herbal atomized composition product.
5. The method for preparing an agilawood sleep-aiding herbal atomized composition according to claim 4, wherein agilawood, ganoderma lucidum, gastrodia elata, clove, dark plum, white hyacinth bean flower, jujube kernel, bunge cherry seed, elsholtzia, polygonatum and American ginseng are selected, and the drying temperature is 50-60 ℃ during drying.
6. The method of claim 5, wherein the drying time is 10-30 minutes.
7. The method for preparing the agilawood sleep-aiding herbal atomized composition according to claim 4, wherein the standby agilawood powder, the ganoderma lucidum powder, the gastrodia elata powder, the clove powder, the smoked plum powder, the white hyacinth bean pollen, the date kernel powder, the bunge cherry seed powder, the elsholtzia powder, the yellow finemeal and the American ginseng powder have the particle sizes of 150-280 meshes.
8. The process of claim 4, wherein the solvent comprises 65-75 wt% ethanol.
9. The method for preparing the agilawood sleep-aiding herbal atomized composition according to claim 4, wherein the volume ratio of the total mass of the standby agilawood powder, the ganoderma lucidum powder, the gastrodia elata powder, the clove powder, the smoked plum powder, the white hyacinth bean pollen, the date kernel powder, the bunge cherry seed powder, the elsholtzia powder, the yellow essence powder and the American ginseng powder to the solvent is 100 g: 10-20 mL.
10. Use of an aerosolized herbal composition comprising lignum Aquilariae Resinatum and sleep aid, wherein the composition prepared according to any one of claims 4-9 is used in aerosolized essential oil products.
CN202210006492.XA 2022-01-05 2022-01-05 Aquilaria sinensis sleep-aiding herbal atomized composition and preparation method and application thereof Pending CN114129670A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116058500A (en) * 2023-02-02 2023-05-05 云南积大生物科技有限公司 A nutritional liver protecting composition and its preparation method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116058500A (en) * 2023-02-02 2023-05-05 云南积大生物科技有限公司 A nutritional liver protecting composition and its preparation method

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Application publication date: 20220304