CN114096674A - 环状多核糖核苷酸的给药方法 - Google Patents

环状多核糖核苷酸的给药方法 Download PDF

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CN114096674A
CN114096674A CN202080044871.7A CN202080044871A CN114096674A CN 114096674 A CN114096674 A CN 114096674A CN 202080044871 A CN202080044871 A CN 202080044871A CN 114096674 A CN114096674 A CN 114096674A
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阿瓦克·卡维吉安
亚历山德拉·索菲·德波尔
尼古拉斯·麦卡特尼·普拉吉斯
埃里卡·加布里埃尔·韦恩斯坦
凯瑟琳·西富恩特斯-罗贾斯
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Flagship Venture & Innovation No6 Co ltd
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CN202080044871.7A 2019-06-19 2020-06-19 环状多核糖核苷酸的给药方法 Pending CN114096674A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962863725P 2019-06-19 2019-06-19
US62/863,725 2019-06-19
PCT/US2020/038835 WO2020257727A1 (en) 2019-06-19 2020-06-19 Methods of dosing circular polyribonucleotides

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US (2) US20220296729A1 (https=)
EP (1) EP3987038A1 (https=)
JP (2) JP2022536951A (https=)
KR (1) KR20220024647A (https=)
CN (1) CN114096674A (https=)
AU (1) AU2020296190A1 (https=)
CA (1) CA3140594A1 (https=)
IL (1) IL288983A (https=)
MA (1) MA56538A (https=)
WO (1) WO2020257727A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116870004A (zh) * 2023-02-24 2023-10-13 中南大学 以brd7为靶点在防治自身免疫性疾病药物中的应用
WO2025138501A1 (zh) * 2023-12-29 2025-07-03 复旦大学 一种基于环状rna的现货型体内原位car与肿瘤疫苗联用的免疫治疗技术及其应用

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CN111819185A (zh) 2017-12-15 2020-10-23 旗舰创业创新第六有限责任公司 包含环状多核糖核苷酸的组合物及其用途
WO2020198403A2 (en) 2019-03-25 2020-10-01 Flagship Pioneering Innovations Vi, Llc Compositions comprising modified circular polyribonucleotides and uses thereof
CN114981409A (zh) 2019-09-03 2022-08-30 美洛德生物医药公司 用于基因组整合的方法和组合物
US20230203192A1 (en) * 2020-05-20 2023-06-29 Flagship Pioneering, Inc. Compositions and methods for producing human polyclonal antibodies
BR112023023642A2 (pt) 2021-05-11 2024-01-30 Myeloid Therapeutics Inc Métodos e composições para integração genômica
MX2024003262A (es) 2021-09-17 2024-06-19 Flagship Pioneering Innovations Vi Llc Composiciones y metodos para producir poliribonucleotidos circulares.
KR20240118174A (ko) 2021-12-17 2024-08-02 플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 변성 조건 하에서의 원형 rna의 풍부화를 위한 방법
CN121057577A (zh) 2023-01-27 2025-12-02 赛欧生物医药股份有限公司 经修饰的脂质组合物及其用途
CN117070564B (zh) * 2023-03-30 2024-05-10 安可来(重庆)生物医药科技有限公司 一种用于合成环形rna的质粒及其构建方法与一种环形rna及其体外合成方法

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116870004A (zh) * 2023-02-24 2023-10-13 中南大学 以brd7为靶点在防治自身免疫性疾病药物中的应用
WO2025138501A1 (zh) * 2023-12-29 2025-07-03 复旦大学 一种基于环状rna的现货型体内原位car与肿瘤疫苗联用的免疫治疗技术及其应用

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MA56538A (fr) 2022-04-27
JP2022536951A (ja) 2022-08-22
US20220296729A1 (en) 2022-09-22
AU2020296190A1 (en) 2022-01-06
IL288983A (en) 2022-02-01
CA3140594A1 (en) 2020-12-24
US20230061936A1 (en) 2023-03-02
WO2020257727A1 (en) 2020-12-24
JP2026040556A (ja) 2026-03-09
KR20220024647A (ko) 2022-03-03
EP3987038A1 (en) 2022-04-27

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