CN114053504A - Square medical hemodialyzer - Google Patents
Square medical hemodialyzer Download PDFInfo
- Publication number
- CN114053504A CN114053504A CN202111322986.0A CN202111322986A CN114053504A CN 114053504 A CN114053504 A CN 114053504A CN 202111322986 A CN202111322986 A CN 202111322986A CN 114053504 A CN114053504 A CN 114053504A
- Authority
- CN
- China
- Prior art keywords
- liquid inlet
- dialysate
- cylinder
- liquid
- area
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007788 liquid Substances 0.000 claims abstract description 120
- 238000000502 dialysis Methods 0.000 claims abstract description 72
- 239000012528 membrane Substances 0.000 claims abstract description 64
- 239000008280 blood Substances 0.000 claims abstract description 55
- 210000004369 blood Anatomy 0.000 claims abstract description 55
- 238000009434 installation Methods 0.000 claims abstract description 6
- 238000004891 communication Methods 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 238000004804 winding Methods 0.000 claims description 8
- 230000000694 effects Effects 0.000 description 6
- 239000000835 fiber Substances 0.000 description 5
- 239000012530 fluid Substances 0.000 description 5
- 238000001631 haemodialysis Methods 0.000 description 4
- 230000000322 hemodialysis Effects 0.000 description 4
- 239000012535 impurity Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000012466 permeate Substances 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000003960 organic solvent Substances 0.000 description 3
- 230000000903 blocking effect Effects 0.000 description 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 2
- 230000002349 favourable effect Effects 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 239000012510 hollow fiber Substances 0.000 description 2
- 230000008595 infiltration Effects 0.000 description 2
- 238000001764 infiltration Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 230000010412 perfusion Effects 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 229930003779 Vitamin B12 Natural products 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000005252 bulbus oculi Anatomy 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 description 1
- 229940109239 creatinine Drugs 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000013777 protein digestion Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 239000011715 vitamin B12 Substances 0.000 description 1
- 235000019163 vitamin B12 Nutrition 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1623—Disposition or location of membranes relative to fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1623—Disposition or location of membranes relative to fluids
- A61M1/1625—Dialyser of the outside perfusion type, i.e. blood flow outside hollow membrane fibres or tubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1631—Constructional aspects thereof having non-tubular membranes, e.g. sheets
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
Abstract
The invention discloses a square medical hemodialyzer which comprises a dialysis installation barrel and a dialysis membrane; the dialysis installation cylinder comprises two cylinder covers and a cylinder body, and the two cylinder covers are respectively provided with a blood input port and a blood output port; a dialysate input port and a dialysate output port are arranged on the side wall of the cylinder body; the dialysis membrane is a structure which is composed of double-layer membranes and is provided with a hollow inner cavity, the structure comprises a liquid inlet area and a liquid outlet area, the liquid inlet area is provided with a liquid inlet, and the liquid inlet is communicated with a dialysate input port; the liquid outlet area is provided with a liquid outlet which is communicated with a dialysate output port; two groups of oppositely arranged guide mounting columns are arranged on the inner side of the cylinder cover, and each group of guide mounting columns comprises a plurality of guide mounting columns; one end of the dialysis membrane provided with the liquid inlet area is sequentially and alternately wound on the two groups of guide mounting columns of the cylinder cover provided with the blood outlet, and one end of the dialysis membrane provided with the liquid outlet area is sequentially and alternately wound on the two groups of guide mounting columns of the cylinder cover provided with the blood inlet.
Description
Technical Field
The invention relates to the field of medical hemodialyzers, in particular to a square medical hemodialyzer.
Background
Patients with renal failure cannot discharge protein digestion products, urea, creatinine, phosphate, vitamin B12 and other bodily wastes, and thus need artificial dialysis to compensate for the intrinsic renal excretion function. The common artificial dialysis method is, for example, to dialyze the blood of a patient by using a hemodialyzer, which is an important component of blood purification therapy, wherein the hemodialysis is to draw the blood of the patient out of the body, the blood of the patient flows into a dialysis system, the dialyzer in the dialysis system is provided with a dialysis membrane, and after the blood of the patient contacts the dialysis membrane, some exogenous or endogenous toxins and the like are removed by the dialysis membrane, and the purified blood is returned to the body of the patient, thereby achieving the treatment purpose of purifying the blood.
The hemodialyzer is called dialyzer for short, is a pipeline and a container for solute exchange between blood and dialysate, and is a key part of hemodialysis. The dialyzer mainly comprises a support structure and a dialysis membrane, wherein the dialysis membrane is an important component of the dialyzer and is a semipermeable membrane which only allows molecules smaller than the pore diameter of the membrane to pass through, and the membrane material is an improved cellulose membrane or a synthetic membrane which can be made into a high-flux dialyzer.
The structure of the existing hemodialyzer mainly comprises a shell, a fiber bundle consisting of fiber tubes, packaging glue, an end cover, a dialysate inlet, a dialysate outlet, a blood inlet, a blood outlet and liquid blocking plates positioned at the dialysate inlet and the dialysate outlet, wherein the fiber bundle is loaded into the shell, the dialysate inlet and the blood outlet are positioned at one end of the shell, the dialysate outlet and the blood inlet are positioned at the other end of the shell, the two ends of the fiber bundle are sealed by the packaging glue, and the liquid blocking plates are respectively positioned at the two ends of the shell, are over against the dialysate inlet and the dialysate outlet and are parallel to the shell, so as to prevent the damage to the fiber bundle when the dialysate directly enters a dialysis chamber. For example, publication No. CN109925552A discloses an end cap of a hemodialyzer, a method of manufacturing the same, and a hemodialyzer.
The existing hemodialyzer has the following disadvantages:
1. most of the existing hemodialyzers are cylindrical, the structural shape is rigid, the layout of an internal dialysis structure is restricted, and only tubular or coiled dialysis membranes can be used and are not flexible enough.
2. Because the diameter of the hollow fiber membrane is small, the hollow fiber membrane is difficult to clean thoroughly, not only can organic solvents contact with blood to enter a human body and damage the liver, eyeballs, skin and the like of the human body, but also a large amount of water is needed, and the production and use cost is high.
Disclosure of Invention
The object of the present invention is to overcome the above-mentioned problems and to provide a square medical hemodialyzer.
The purpose of the invention is realized by the following technical scheme:
a square medical hemodialyzer comprises a dialysis mounting cylinder and a dialysis membrane; the dialysis mounting cylinder comprises two cylinder covers and a cylinder body arranged between the two cylinder covers, and the two cylinder covers are respectively provided with a blood input port for inputting blood and a blood output port for outputting blood;
the cross section of the cylinder is a hollow quadrangle, and a dialysate input port for inputting dialysate and a dialysate output port for outputting dialysate are arranged on the side wall of the cylinder; the dialysate output port is communicated with a transfusion tube with a negative pressure function;
the dialysis membrane is a structure which is composed of double-layer membranes and is provided with a hollow inner cavity, the structure comprises a liquid inlet area and a liquid outlet area, the liquid inlet area is provided with a liquid inlet, and the liquid inlet is communicated with a dialysate input port; the liquid outlet area is provided with a liquid outlet which is communicated with a dialysate output port;
two groups of guide mounting columns which are arranged oppositely are arranged on the inner side surface of the cylinder cover, and each group of guide mounting columns comprises a plurality of guide mounting columns; one end of the dialysis membrane provided with the liquid inlet area is sequentially and alternately wound on the two groups of guide mounting columns of the cylinder cover provided with the blood outlet, and one end of the dialysis membrane provided with the liquid outlet area is sequentially and alternately wound on the two groups of guide mounting columns of the cylinder cover provided with the blood inlet.
In a preferred embodiment of the present invention, the cylinder cover is provided with a water collecting cavity, the water collecting cavity is provided with a mesh plate, and the mesh plate is provided with a plurality of meshes. Thus, after entering from the blood input port, the blood is converged in the water converging cavity and then dispersedly flows out from the meshes of the mesh plate, so that the blood to be dialyzed uniformly enters the inner cavity of the cylinder body.
Furthermore, two opposite side walls in the water collecting cavity are respectively provided with a limiting fixing part; the screen plate is fixed and limited on the limiting fixing part.
In a preferred embodiment of the present invention, two dialysate input ports and two dialysate output ports are provided;
the two liquid inlets are respectively arranged at two ends of the liquid inlet area; the liquid outlet is provided with two, sets up respectively at the both ends of going out the liquid district. Through above-mentioned structure, can follow the both ends input dislysate that enters the liquid district, improve the input and the speed that flows of dislysate, can improve dialysis efficiency and obtain better dialysis effect.
In a preferred embodiment of the present invention, the dialysis membrane is provided with winding zones at both ends thereof near the cover, and the liquid inlet zone and the liquid outlet zone are located between the two winding zones. Through the structure, the winding area is wound on the guide mounting column, so that the installation is realized, the liquid inlet area and the liquid outlet area can be prevented from being extruded by the guide mounting column, and the dialysate can be smoothly circulated in the liquid inlet area and the liquid outlet area.
In a preferred embodiment of the present invention, a communication hole is provided between the liquid inlet area and the liquid outlet area, and a cross-sectional area of the communication hole is smaller than a cross-sectional area of the liquid inlet. The communication hole is arranged to allow a part of the dialysate to permeate to the outside of the membrane, so that the dialysate is fused with the blood outside the membrane, and the fused mixed liquid continuously flows downwards; the other part of the dialysate flows into the liquid outlet area from the communication hole and then flows to the dialysis loop from the liquid outlet area. Like this, when the dislysate carries out the infiltration, can accelerate the flow of dislysate for the transport of dislysate is more smooth, is favorable to improving dialysis efficiency.
Further, the cross-sectional area of the communication hole and the cross-sectional area of the liquid inlet satisfy the following relationship:
wherein S is1Is the cross-sectional area of the liquid inlet, S2The sectional area of the communicating hole; l is1The length of the liquid inlet area in the length direction of the cylinder body, L2The length of the communicating hole.
Further, the length of the liquid inlet area in the length direction of the cylinder body is equal to the length of the liquid outlet area in the length direction of the cylinder body, and the relationship between the length of the communication hole and the total length of the dialysis membrane for flowing of the dialysate is as follows:
Lgeneral assembly=L1+L2+L3;
Wherein L is1The length of the liquid inlet area in the length direction of the cylinder body, L2Is the length of the communicating hole, L3The length of the liquid outlet area in the length direction of the cylinder body.
Through the parameters, the dialysate can smoothly flow in a circulating way, and importantly, the maximum seepage rate and the mixing degree of the dialysate and blood (impurities) can be obtained, and a better dialysate filtering effect and a better hemodialysis effect are obtained.
Further, when the liquid inlet is provided with two liquid inlets which are respectively arranged at two ends of the liquid inlet area, the communication hole is communicated with the middle position of the liquid inlet area and the liquid outlet area.
Compared with the prior art, the invention has the following beneficial effects:
1. the square medical hemodialyzer adopts the square dialysis mounting barrel, and the dialysis membrane is wound in the dialysis mounting barrel along the S-shaped track, so that the whole dialysis membrane is used, the process difficulty of producing parts of the dialyzer is reduced, the layout of an internal dialysis structure is opened, the use of a tubular or coiled dialysis membrane is not limited, and the square medical hemodialyzer has better flexibility.
2. When the dialysis membrane is cleaned, the dialysis membrane can be unfolded straightly, the inner surface and the outer surface of the dialysis membrane are directly cleaned, the organic solvent can be cleaned thoroughly, and the organic solvent is prevented from entering a human body and damaging the human body.
3. Because the dialysis membrane can be unfolded in a large area, the dialysis membrane is convenient to clean, the water consumption can be saved, and the production and use cost is reduced.
4. Through set up into liquid district and play liquid district in same dialysis membrane piece, go into liquid district and dialysate input port intercommunication, go out liquid district and dialysate output port intercommunication, the dialysate oozes out from going into the liquid district earlier, fuses with the outer blood of membrane, again from getting back to out the liquid district, like this at the in-process that oozes, can filter the impurity in the dialysate, prevents that the impurity in the dialysate from polluting blood.
Drawings
Fig. 1 is a schematic perspective view of a square medical hemodialyzer in the present invention.
Fig. 2 is a schematic perspective view of fig. 1 with the canister body and one of the canister covers hidden.
Fig. 3-4 are perspective exploded views of two different perspectives of a square medical hemodialyzer in accordance with the present invention.
Fig. 5 is a schematic perspective view of the cartridge cover according to the present invention.
Fig. 6 is a schematic perspective view of a dialysis membrane according to the present invention.
Fig. 7 is a front view of the dialysis membrane of the present invention after it is flattened, wherein the arrows of thick solid lines represent the flow direction of blood and the arrows of thin solid lines represent the flow direction of dialysate.
Detailed Description
In order to make those skilled in the art understand the technical solutions of the present invention well, the following description of the present invention is provided with reference to the embodiments and the accompanying drawings, but the embodiments of the present invention are not limited thereto.
Referring to fig. 1-4, the square medical hemodialyzer in the present embodiment includes a dialysis mounting cartridge and a dialysis membrane 1; the dialysis mounting cylinder comprises two cylinder covers 2 and a cylinder body 3 arranged between the two cylinder covers 2, and a blood input port 3-1 for inputting blood and a blood output port 3-2 for outputting blood are respectively arranged on the two cylinder covers 2; the cross section of the cylinder body 3 is a hollow quadrangle, and a dialysate input port 3-1 for inputting dialysate and a dialysate output port 3-2 for outputting dialysate are arranged on the side wall of the cylinder body 3; the dialysate output port 3-2 is communicated with a transfusion tube with negative pressure function.
Referring to fig. 1-7, the dialysis membrane 1 is a structure composed of a double-layer membrane and having a hollow inner cavity (the dialysis membrane 1 is obtained by bonding two layers of membranes), the structure includes a liquid inlet area 1-1 and a liquid outlet area 1-2, the liquid inlet area 1-1 is provided with a liquid inlet 1-1-1, and the liquid inlet 1-1-1 is communicated with a dialysate input port 3-1; the liquid outlet area 1-2 is provided with a liquid outlet 1-2-1, and the liquid outlet 1-2-1 is communicated with a dialysate output port 3-2. Two groups of guide mounting columns 4 which are arranged oppositely are arranged on the inner side surface of the cylinder cover 2, and each group of guide mounting columns 4 comprises a plurality of guide mounting columns 4; one end of the dialysis membrane 1 provided with the liquid inlet area 1-1 sequentially and alternately winds on two groups of guide mounting columns 4 of the cylinder cover 2 provided with the blood outlet 3-2, and one end of the dialysis membrane 1 provided with the liquid outlet area 1-2 sequentially and alternately winds on two groups of guide mounting columns 4 of the cylinder cover 2 provided with the blood inlet 3-1. 5
Referring to fig. 3-5, a water collecting cavity is arranged on the cylinder cover 2, a screen plate 5 is arranged at the water collecting cavity, and a plurality of meshes are arranged on the screen plate 5. Thus, after entering from the blood input port 3-1, the blood is converged in the water collecting chamber and then is dispersed and flowed out from the meshes of the mesh plate 5, so that the blood to be dialyzed uniformly enters the inner cavity of the cylinder 3.
Furthermore, two opposite side walls in the water collecting cavity are respectively provided with a limiting fixing part 2-3; the screen plate 5 is fixed and limited on the limit fixing part 2-3.
Referring to fig. 1-7, two dialysate input ports 3-1 and two dialysate output ports 3-2 are provided; two liquid inlets 1-1-1 are arranged and are respectively arranged at two ends of the liquid inlet area 1-1; the two liquid outlets 1-2-1 are respectively arranged at two ends of the liquid outlet area 1-2. Through the structure, the dialysate can be input from the two ends of the dialysate inlet area 1-1, so that the input and flowing speed of the dialysate are improved, the dialysis efficiency can be improved, and a better dialysis effect can be obtained.
Referring to fig. 6-7, the two ends of the dialysis membrane 1 close to the cover 2 are provided with winding zones 1-3, and the liquid inlet zone 1-1 and the liquid outlet zone 1-2 are positioned between the two winding zones 1-3. Through the structure, the winding area 1-3 is wound on the guide mounting column 4, so that the installation is realized, the liquid inlet area 1-1 and the liquid outlet area 1-2 can be prevented from being extruded by the guide mounting column 4, and the dialysate can be ensured to smoothly circulate in the liquid inlet area 1-1 and the liquid outlet area 1-2.
Referring to fig. 7, a communicating hole 1-4 is arranged between the liquid inlet area 1-1 and the liquid outlet area 1-2, and the sectional area of the communicating hole 1-4 is smaller than that of the liquid inlet 1-1-1. The communication holes 1-4 are arranged for the purpose that a part of the dialysate permeates to the outside of the membrane and is fused with the blood outside the membrane, and the fused mixed liquid continuously flows downwards; the other part of the dialysate flows from the communication hole 1-4 to the liquid outlet area 1-2 and then flows from the liquid outlet area 1-2 to the dialysis circuit. Like this, when the dislysate carries out the infiltration, can accelerate the flow of dislysate for the transport of dislysate is more smooth, is favorable to improving dialysis efficiency.
Further, the sectional area of the communicating hole 1-4 and the sectional area of the liquid inlet 1-1-1 satisfy the following relationship:
wherein S is1Is the cross-sectional area of the liquid inlet 1-1-1, S2The sectional area of the communicating hole is 1-4; l is1The length of the liquid inlet area 1-1 in the length direction of the cylinder 3, L2The length of the communicating holes 1-4.
Further, the length of the liquid inlet area 1-1 in the length direction of the cylinder 3 is equal to the length of the liquid outlet area 1-2 in the length direction of the cylinder 3, and the relationship between the length of the communication hole 1-4 and the total length of the dialysis membrane 1 for flowing of the dialysate is as follows:
Lgeneral assembly=L1+L2+L3;
Wherein L is1The length of the liquid inlet area 1-1 in the length direction of the cylinder 3, L2The length of the communicating hole 1-4, L3The length of the liquid outlet area 1-2 in the length direction of the cylinder 3.
Through the parameters, the dialysate can smoothly flow in a circulating way, and importantly, the maximum seepage rate and the mixing degree of the dialysate and blood (impurities) can be obtained, and a better dialysate filtering effect and a better hemodialysis effect are obtained.
Further, when two liquid inlets 1-1-1 are arranged and respectively arranged at two ends of the liquid inlet area 1-1, the communication hole 1-4 is communicated with the middle position of the liquid inlet area 1-1 and the liquid outlet area 1-2.
Referring to fig. 1-7, the working principle of the square medical hemodialyzer in the present embodiment is:
during operation, the dialysate is introduced into the dialysis membrane 1 through the dialysate input port 3-1, and the dialysate fills the inner cavity of the dialysis membrane 1 along the S-shaped track. At the same time, the blood to be dialyzed is introduced into the dialysis mounting cylinder through the blood inlet port 3-1, and the blood to be dialyzed flows down along the gap of the dialysis membrane 1 (flows from the gap of the outlet region 1-2 to the gap of the inlet region 1-1).
During the process of dialysate flow, the dialysate permeates to the outside of the membrane and is merged with the blood outside the membrane, and the merged mixed liquid continues to flow down along the gap of the dialysis membrane 1 (from the gap of the fluid inlet region 1-1 to the gap of the fluid outlet region 1-2).
Further, because the dialysate output port 3-2 is communicated with the perfusion tube with negative pressure, under the action of negative pressure, when the dialysate flows to the gap of the fluid outlet area 1-2, the dialysate will carry the waste in the blood to permeate into the fluid outlet area 1-2 of the dialysis membrane 1, and then flow to the perfusion tube from the fluid outlet area 1-2 for subsequent treatment. And the dialyzed blood continues to flow downwards and finally flows back to the human body from the blood output port 3-2 of the dialysis installation cylinder.
The present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents and are included in the scope of the present invention.
Claims (9)
1. A square medical hemodialyzer comprises a dialysis mounting cylinder and a dialysis membrane; the dialysis installation cylinder is characterized by comprising two cylinder covers and a cylinder body arranged between the two cylinder covers, wherein the two cylinder covers are respectively provided with a blood input port for inputting blood and a blood output port for outputting blood;
the cross section of the cylinder is a hollow quadrangle, and a dialysate input port for inputting dialysate and a dialysate output port for outputting dialysate are arranged on the side wall of the cylinder; the dialysate output port is communicated with a transfusion tube with a negative pressure function;
the dialysis membrane is a structure which is composed of double-layer membranes and is provided with a hollow inner cavity, the structure comprises a liquid inlet area and a liquid outlet area, the liquid inlet area is provided with a liquid inlet, and the liquid inlet is communicated with a dialysate input port; the liquid outlet area is provided with a liquid outlet which is communicated with a dialysate output port;
two groups of guide mounting columns which are arranged oppositely are arranged on the inner side surface of the cylinder cover, and each group of guide mounting columns comprises a plurality of guide mounting columns; one end of the dialysis membrane provided with the liquid inlet area is sequentially and alternately wound on the two groups of guide mounting columns of the cylinder cover provided with the blood outlet, and one end of the dialysis membrane provided with the liquid outlet area is sequentially and alternately wound on the two groups of guide mounting columns of the cylinder cover provided with the blood inlet.
2. The square medical hemodialyzer according to claim 1, wherein a water collecting chamber is provided on the cover, a mesh plate is provided at the water collecting chamber, and a plurality of meshes are provided on the mesh plate.
3. The square medical hemodialyzer of claim 2, wherein two opposing side walls of the water collecting chamber are each provided with a stopper fixing portion; the screen plate is fixed and limited on the limiting fixing part.
4. The square medical hemodialyzer of claim 1, wherein there are two of the dialysate input ports and the dialysate output ports;
the two liquid inlets are respectively arranged at two ends of the liquid inlet area; the liquid outlet is provided with two, sets up respectively at the both ends of going out the liquid district.
5. The square medical hemodialyzer according to claim 1, wherein the dialysis membrane is provided with winding zones near both ends of the cover, and the inlet and outlet zones are located between the two winding zones.
6. The square medical hemodialyzer according to claim 1 or 5, wherein a communication hole having a sectional area smaller than that of the liquid inlet port is provided between the liquid inlet region and the liquid outlet region.
7. The square medical hemodialyzer according to claim 6, wherein a sectional area of the communication hole and a sectional area of the liquid inlet satisfy the following relationship:
wherein S is1Is the cross-sectional area of the liquid inlet, S2The sectional area of the communicating hole; l is1The length of the liquid inlet area in the length direction of the cylinder body, L2The length of the communicating hole.
8. The square medical hemodialyzer according to claim 7, wherein the length of the liquid inlet region in the longitudinal direction of the barrel is equal to the length of the liquid outlet region in the longitudinal direction of the barrel, and the length of the communication hole and the total length of the dialysis membrane for flowing the dialysate have a relationship of:
Lgeneral assembly=L1+L2+L3;
Wherein L is1The length of the liquid inlet area in the length direction of the cylinder body, L2Is the length of the communicating hole, L3The length of the liquid outlet area in the length direction of the cylinder body.
9. The square medical hemodialyzer according to claim 6, wherein when the liquid inlet ports are provided in two and disposed at both ends of the liquid inlet zone, respectively, the communication holes communicate at a middle position of the liquid inlet zone and the liquid outlet zone.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111322986.0A CN114053504A (en) | 2021-11-09 | 2021-11-09 | Square medical hemodialyzer |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111322986.0A CN114053504A (en) | 2021-11-09 | 2021-11-09 | Square medical hemodialyzer |
Publications (1)
Publication Number | Publication Date |
---|---|
CN114053504A true CN114053504A (en) | 2022-02-18 |
Family
ID=80274415
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202111322986.0A Pending CN114053504A (en) | 2021-11-09 | 2021-11-09 | Square medical hemodialyzer |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN114053504A (en) |
-
2021
- 2021-11-09 CN CN202111322986.0A patent/CN114053504A/en active Pending
Similar Documents
Publication | Publication Date | Title |
---|---|---|
RU2661275C2 (en) | Dialysis apparatus with dialyzer | |
RU2292225C2 (en) | Hemodiafiltration/hemofiltration cartridge | |
US20030080047A1 (en) | Hemodialyzer having improved dialysate perfusion | |
JP2010536473A5 (en) | ||
US5942112A (en) | Hollow fiber ultradialyzer apparatus | |
US4173537A (en) | Integral artificial kidney unit | |
JP3284028B2 (en) | Dialysis machine | |
CN102600520B (en) | Hemodialyzer | |
CN114053504A (en) | Square medical hemodialyzer | |
CN114053505A (en) | Manufacturing method of square hemodialyzer and dialysis method | |
CN108697987A (en) | System and method for filtering fluid | |
CN209173054U (en) | A kind of filtering device for blood dialysis with blood filtering function | |
JP4328902B2 (en) | Online large-volume fluid replacement hemodialyzer | |
JP4807912B2 (en) | Hollow fiber membrane module and manufacturing method thereof | |
US20050000898A1 (en) | Bio-liquid treatment device | |
CN113456914B (en) | Flat plate winding type dialyzer | |
JP2002095740A (en) | Method for returning residual blood in blood circuit and device for blood purification | |
CN113456915A (en) | Spiral winding medical dialyzer | |
CN113694283A (en) | Double-roll medical hemodialyzer and dialysis equipment | |
CN218793314U (en) | Infusion apparatus for hemodialysis room | |
JP5347602B2 (en) | Blood processing equipment | |
KR100929147B1 (en) | Hemodialysis Machine with Improved Reflux | |
CN113694282A (en) | Manufacturing method of double-roll medical hemodialyzer and dialysis method | |
JP2000070360A (en) | Hollow fiber membrane type dialyzer | |
CN209092335U (en) | Dialysis tubing |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20220218 |