CN114046596B - Indoor air quality control system and method based on TRP biochemical index detection - Google Patents
Indoor air quality control system and method based on TRP biochemical index detection Download PDFInfo
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Abstract
The invention discloses an indoor air quality control system and method based on TRP biochemical index detection, wherein an inflammation factor sampling detector in the system detects inflammation factor data and outputs the data to an early warning processing system; the early warning processing system outputs an early warning signal to a user interface when the inflammatory factor data exceeds a set value, and outputs a signal to a TRP protein expression quantity sampling detector when the inflammatory factor data does not exceed the set value; the TRP protein expression quantity sampling detector is used for obtaining the TRP (transient receptor potential) protein expression quantity; the operation control system takes the nondimensionalized TRP protein expression ratio as a control signal and outputs a corresponding control signal to the fresh air purification system and the dehumidification system as a regulation and control basis; fresh air purification system and dehumidification system can be according to control signal with the coordinated control operation of joint work mode. The invention utilizes the characteristic indexes of the influence of the indoor environment multi-parameters on the human body comfort and health to regulate and control the indoor air treatment system, and slows down the generation of sick building syndrome under the requirement of energy conservation.
Description
Technical Field
The invention relates to the technical field of indoor air quality control, in particular to an indoor air quality control system and method based on TRP biochemical index detection.
Background
With the development of economy and air conditioning technology in China, air conditioning systems are generally applied to building interiors, but more and more complaints of 'air conditioning diseases' are generated. Under the condition that various indoor pollutants reach the standard, people find that a series of unidentified uncomfortable symptoms complain symptoms still exist in the indoor air-conditioning environment of a building, and the symptoms are defined as Sick Building Syndrome (SBS) by the world health organization, which reflects the influence of the comprehensive effect of the hot and humid environment of the indoor air conditioner and the trace pollution of air on the comfort and health of a human body.
In actual buildingsIn the method, the indoor air quality environment state is not determined by a certain parameter, but is generated by the combined action of multiple air pollutants, and is influenced by other factors including temperature, humidity and wind speed, wherein the high-humidity environment not only can breed bacteria and aggravate the toxicity of the multiple pollutants, but also can form macromolecular aerosol in air to attach various pollutants in the supersaturated humidity environment, so that the harm of human body inhalation is enhanced. The existing international and national standards only list a limited number of single pollutants, such as formaldehyde, PM2.5 and CO 2 The safety limit value of the like, but the actual influence of coexistence of various pollutants and high humidity coupling influence on the human body is not considered, which is one of the main factors of the human body causing unknown uncomfortable symptoms; on the other hand, when the air conditioning system in the prior art is used for adjusting an indoor thermal environment, only the influence of the environmental temperature and humidity on the human body comfort is considered, the environmental regulation and control of the health state of the human body are not considered, and an air quality control system is additionally arranged; because the indoor air quality monitoring system in the prior art does not have the conditions of an outdoor weather station due to cost limitation, only a few pollutants can be monitored, the accuracy is poor, and comprehensive control parameters cannot be provided for an air quality control system; the existing control method of the air purification system has the contradiction that the energy consumption is high when the air purification system is started in a full time period, and the air quality is not guaranteed when a user is selectively closed due to high energy consumption. Therefore, the methods for controlling the indoor air quality environment in the prior art have many problems in the aspects of system coordination, parameter monitoring, regulation and control basis, accuracy, reliability, comprehensiveness and the like of energy-saving management, and therefore the generation of sick building syndrome cannot be effectively solved. However, a few multi-parameter coordination control systems in the prior art are based on energy consumption and environment monitoring, and lack a physiological index control basis for comprehensively reflecting the influence of indoor environment multi-parameters on human comfort and health, and the regulation and control precision of the system needs to be further improved.
Disclosure of Invention
Aiming at the defects in the prior art, the technical problems to be solved by the invention are as follows: how to provide an indoor air quality control system and method based on TRP biochemical index detection, which can comprehensively reflect the characteristics of influence of multiple parameters of an indoor environment on the comfort and health of a human body, thereby effectively relieving the generation of sick building syndrome.
In order to solve the technical problems, the invention adopts the following technical scheme:
an indoor air quality control system based on TRP biochemical index detection comprises an inflammation factor sampling detector, an early warning processing system, a user interface, a TRP protein expression quantity sampling detector, a skin temperature sensor, an air humidity sensor, an operation control system, a fresh air purification system and a dehumidification system;
the output end of the inflammation factor sampling detector is in data connection with the input end of the early warning processing system and is used for detecting inflammation factor data and outputting the inflammation factor data to the early warning processing system;
the output end of the early warning processing system is respectively in data connection with the input end of the user interface and the input end of the TRP protein expression quantity sampling detector, and is used for outputting an early warning signal to the user interface when the inflammation factor data exceeds a set value and outputting a signal to the TRP protein expression quantity sampling detector when the inflammation factor data does not exceed the set value;
the output end of the TRP protein expression quantity sampling detector is in data connection with the input end of the operation control system and is used for obtaining the TRP protein expression quantity and converting the TRP protein expression quantity into a corresponding nerve electric pulse signal to be output to the operation control system;
the output end of the skin temperature sensor is in data connection with the input end of the operation control system and is used for collecting a human skin temperature value and outputting the human skin temperature value to the operation control system;
the output end of the air humidity sensor is in data connection with the input end of the operation control system and is used for collecting an air humidity value RH and outputting the air humidity value RH to the operation control system;
the output end of the operation control system is respectively in data connection with the input end of the fresh air purification system and the input end of the dehumidification system and is used for outputting corresponding control signals to the fresh air purification system and the dehumidification system according to data information of each input end of the operation control system;
the fresh air purification system is used for controlling the operation of the fresh air system and the purification system according to the control signal of the operation control system.
The working principle of the invention is as follows: when the indoor air quality control system works, firstly, an inflammation factor sampling detection result is obtained by the inflammation factor sampling detector and the obtained result is output to the early warning processing system; the early warning processing system judges the data after receiving the inflammatory factor sampling detection result, when the data of the inflammatory factor sampling detection result exceeds a set value, the situation that pollutants exceed the standard exists in the indoor environment at the moment is represented, the early warning processing system outputs a signal to a user interface, the user interface sends out early warning information that the pollutants exceed the standard, related personnel are automatically informed to detect and process the indoor pollutants, and after the indoor pollutants are processed, the inflammatory factor sampling detection detector obtains the inflammatory factor sampling detection result again until the numerical value of the inflammatory factor sampling detection result is smaller than the set value.
When the early warning processing system detects that the value of the inflammatory factor sampling detection result is smaller than a set value, the concentration of indoor pollutants is in an allowable range at the moment, the early warning processing system sends a control signal to a TRP protein expression quantity sampling detector, so that the TRP protein expression quantity sampling detector collects human tissue fluid to obtain TRP protein expression quantity, and converts the TRP protein expression quantity into a corresponding neural electric pulse signal Si, the neural electric pulse signal Si is a neural electric pulse signal expression quantity influenced by the comprehensive action of temperature and pollutants, and a skin temperature sensor collects a human skin temperature value Tskin; according to a human skin temperature value Tskin acquired by a skin temperature sensor, searching and obtaining a standard neuroelectric pulse signal S0 at the temperature, wherein the S0 value is the expression quantity of the neuroelectric pulse signal only affected by the temperature; then, calculating the obtained neural electric pulse signal Si and the standard neural electric pulse signal S0 to obtain an operation control signal taking the non-dimensionalized TRP contrast expression ratio R as a value basis; the operation control system adjusts the combined working mode of the fresh air purification system and the dehumidification system according to the numerical range of the operation control signal R, so that the adjustment of the combined working mode of the fresh air purification system and the dehumidification system comprehensively reflects the influence of the indoor environment parameters on the comfort and health of the human body and the energy-saving requirement, the fresh air purification system and the dehumidification system comprehensively adjust the environmental factors comprehensively influencing the comfort and health of the human body under the energy-saving requirement, the adjustment mode comprehensively reflects the characteristic of the influence of the indoor environment parameters on the comfort and health of the human body, and the generation of sick building syndrome is solved.
In the invention, the human biochemical indexes comprise protein channel expression quantity of a temperature receptor TRP (transient receptor potential) and inflammatory factors IL-4, IL-1 beta, IgE and the like; the temperature receptor TRP (transient receptor potential) channel is a cationic channel protein widely distributed in peripheral and central nervous systems, researches show that the expression quantity of the TRP channel is influenced by comprehensive effects of temperature, humidity and pollutants and can be used as a biological mechanism index of human body comfort, inflammatory factors such as IL-4, IL-1 beta, IgE and the like can be used as a biological mechanism index of human body health degree, and the biological mechanism indexes form a potential indoor air quality regulation index basis, so the scheme comprehensively considers the factors, converts the obtained expression quantity of the TRP protein into corresponding nerve electric pulse signals, further outputs the nerve electric pulse signals to an arithmetic control system, and utilizes the arithmetic control system to control a fresh air purification system and a dehumidification system, and the joint control of the arithmetic control system to the fresh air purification system and the dehumidification system can better meet the requirement of human body on indoor environment comfort The adaptability requirement can more comprehensively reflect the characteristics of influence of multiple indoor environment parameters on the comfort and health of the human body, thereby solving the generation of sick building syndrome.
An indoor air quality control method based on TRP biochemical index detection samples the indoor air quality control system based on TRP biochemical index detection, and comprises the following steps:
step 1) the inflammation factor sampling detector acquires an inflammation factor sampling detection result and outputs the result to the early warning processing system;
step 2) the early warning processing system judges the inflammatory factor sampling detection result, and executes step 3) when the inflammatory factor sampling detection result exceeds a set value and executes step 4) when the inflammatory factor sampling detection result does not exceed the set value;
step 3), the user interface sends out early warning information that pollutants exceed the standard;
step 4) the TRP protein expression quantity sampling detector collects human tissue fluid to obtain TRP protein expression quantity and detects the TRP protein expression quantity to obtain a corresponding neural electric pulse signal Si, the air humidity sensor is used for collecting an air humidity value RH, meanwhile, the skin temperature sensor collects a human skin temperature value Tskin, and a non-contact infrared sensor can be adopted for optimal skin temperature monitoring;
step 5) searching for a standard neuroelectric pulse signal S0 at the temperature according to the human skin temperature value Tskin acquired by the skin temperature sensor;
step 6), the operation control system calculates to obtain an operation control signal R according to the data obtained in the step 4) and the step 5);
step 7), the operation control system adjusts the combined working mode of the fresh air purification system and the dehumidification system according to the numerical range of the operation control signal R;
step 8) returns to execute step 1).
In the control method, the comprehensive control of the indoor environmental quality is realized by using the parameters of human body biochemical indexes including temperature receptor TRP (transient receptor potential) protein channel expression quantity, inflammatory factors IL-4, IL-1 beta, IgE and the like; the temperature receptor TRP (transient receptor potential) channel is a kind of cation channel protein which is widely distributed in the peripheral and central nervous systems, researches show that the expression quantity of the TRP channel is influenced by the comprehensive action of temperature, humidity and pollutants and can be used as a biological mechanism index of human body comfort, inflammatory factors such as IL-4, IL-1 beta, IgE and the like can be used as a biological mechanism index of human body health degree, and the inflammatory factors form a potential indoor air quality regulation index basis, so that the control method of the scheme can comprehensively reflect the characteristic that a plurality of parameters in an indoor environment influence the human body comfort and health by comprehensively considering the factors, thereby solving the generation of sick building syndrome.
Preferably, in step 6), the value of the operation control signal is based on a dimensionless ratio R of the TRP protein expression, the numerical value of R indicates the influence of the non-thermal environmental factors on the health status of the human body, and the operation control signal R is a dimensionless constant after the influence of thermal stress on the TRP protein expression is eliminated, specifically, the operation control signal R is calculated according to the following method:
thus, the operation control signal R is a dimensionless constant after the influence of thermal stress on the TRP protein expression quantity is eliminated, the numerical characteristics of the operation control signal R reflect the influence of air pollutants and humidity outside the thermal environment on the human body, and the influence of non-thermal environment factors on the health state of the human body is indicated.
When R is less than 1, the comprehensive stimulation of the indoor environment on the human body is small, and the human body state is good, so that the load of an indoor air quality control system can be properly reduced; when R is larger than 1, the human body is not only stimulated by temperature, but also stimulated by pollutants and the like, and the operation level of an indoor air quality control system needs to be improved, so that the stimulation amount of pollution factors is reduced.
Preferably, in the step 7), the combined working mode of the fresh air purification system and the dehumidification system is as follows:
the fresh air purification system and the dehumidification system are both started;
or both the fresh air purification system and the dehumidification system are closed;
or the dehumidification system is started, and the fresh air purification system is closed;
or the dehumidification system is closed and the fresh air purification system is opened.
Therefore, the fresh air purification system and the dehumidification system can work in different working modes according to different value ranges of the operation control signal R, and further optimal control on indoor environment quality is achieved.
Preferably, in step 7),
when R is more than or equal to 1+ X, the fresh air purification system and the dehumidification system are both started, and the air handling capacity Q or the operating power W of the fresh air purification system is regulated within a rated range according to the following formula:
Q＝R n Q O
W＝R m W O ；
when R is less than 1-Y, the fresh air purification system and the dehumidification system are both closed;
when 1-Y is less than or equal to R<1+ X and RH is greater than or equal to RH o When the fresh air purification system is started, the dehumidification system is started, and the fresh air purification system is closed;
when 1-Y is less than or equal to R<1+ X, and RH<RH o When the fresh air purification system is started, the dehumidification system is closed, and the fresh air purification system is started and operates according to the minimum air handling capacity and power of the fresh air purification system;
in the formula: m and n are constants, Q o Is the minimum air handling capacity, W, of the fresh air purification system o Is the minimum operating power of the fresh air purification system, and is selected according to the maximum value when the calculated value of the air handling capacity Q or the operating power W of the fresh air purification system exceeds the rated range, X and Y are constants with the value range of 0.1-1.0, RH o The value is a preset constant value, and the value range is 30-80%, and preferably 50%.
Preferably, in step 1), the inflammation factor sampling detector obtains a human inflammation factor sampling result in an invasive or non-invasive manner.
Preferably, the inflammation factor sampling detector obtains an inflammation factor sampling result by detecting blood, exhaled air, saliva, skin sweat or urine of a human body.
Therefore, when the inflammatory factors are sampled, the invasive sampling method can be adopted to sample the blood of the human body, and the data obtained by the invasive sampling method is more accurate; the noninvasive sampling method can be adopted to sample tissue fluids such as expired gas, saliva, skin sweat, urine and the like of a human body, the noninvasive sampling mode is simpler and more convenient to operate, and when the noninvasive sampling method is specifically adopted, the inflammatory factor sampling detector can be arranged near an air purification system and a dehumidification system panel or on a certain position of a remote controller or even a toilet and other places, so that the sampling detection is convenient.
Preferably, in step 1), the inflammatory factor sampling result obtained by the inflammatory factor sampling detector comprises IL-4, IL-1 beta and IgE.
Therefore, the influence of indoor pollutants on human bodies can be well reflected by collecting the parameters, and data basis is provided for the adjustment of indoor air quality.
Preferably, in step 3), step 1) is executed again after the detection treatment of the pollutant is performed.
Therefore, when the concentration of the indoor pollutants exceeds the standard, the concentration of the indoor pollutants can be always below an allowable value by processing the pollutants and then detecting the sampling result of the inflammatory factors again.
Compared with the prior art, the indoor air quality control method and system based on TRP biochemical index detection, provided by the invention, utilize essential mechanism indexes of inflammatory factors IL-4, IL-1 beta, IgE and the like of a human body influenced by an air quality environment and the characteristic that the expression quantity of a temperature receptor TRP channel is influenced by the comprehensive action of temperature and pollutants, take the essential mechanism indexes as a biological mechanism index of the influence degree of human body health and comfort by the air quality environment, and serve as a new index basis of indoor air quality control, so that the indoor air environment control strategy level and efficiency are improved. Experiments prove that compared with the traditional control method, the control method provided by the invention can be used for more comprehensively and accurately adjusting the air quality environmental factors influencing the comfort and health of human bodies, and the health and comfort degree of the indoor air environment created by the adjusting and controlling method is greatly improved, so that the generation of sick building syndrome can be effectively relieved.
Drawings
FIG. 1 is a system block diagram of an indoor air quality control system based on TRP biochemical indicator detection according to the present invention;
FIG. 2 is a flow chart of the indoor air quality control method based on TRP biochemical index detection according to the present invention;
fig. 3 is a graph of the relationship between the standard neuroelectric impulse signal S0 and the human skin temperature value Tskin.
Detailed Description
The invention will be further explained with reference to the drawings and the embodiments.
As shown in the attached figure 1, the indoor air quality control system based on TRP biochemical index detection comprises an inflammation factor sampling detector, an early warning processing system, a user interface, a TRP protein expression quantity sampling detector, a skin temperature sensor, an air humidity sensor, an operation control system, a fresh air purification system and a dehumidification system;
the output end of the inflammation factor sampling detector is in data connection with the input end of the early warning processing system and is used for detecting inflammation factor data and outputting the inflammation factor data to the early warning processing system;
the output end of the early warning processing system is respectively in data connection with the input end of the user interface and the input end of the TRP protein expression quantity sampling detector, and is used for outputting an early warning signal to the user interface when the inflammation factor data exceeds a set value and outputting a signal TRP protein expression quantity sampling detector when the inflammation factor data does not exceed the set value;
the output end of the TRP protein expression quantity sampling detector is in data connection with the input end of the operation control system and is used for obtaining the TRP protein expression quantity and converting the TRP protein expression quantity into a corresponding nerve electric pulse signal to be output to the operation control system;
the output end of the skin temperature sensor is in data connection with the input end of the operation control system and is used for collecting the skin temperature value of the human body and outputting the skin temperature value to the operation control system;
the output end of the air humidity sensor is in data connection with the input end of the operation control system and is used for collecting an air humidity value RH and outputting the air humidity value RH to the operation control system;
the output end of the operation control system is respectively in data connection with the input end of the fresh air purification system and the input end of the dehumidification system and is used for outputting corresponding control signals to the fresh air purification system and the dehumidification system according to data information of each input end of the operation control system;
the fresh air purification system is used for controlling the operation of the fresh air system and the purification system according to the control signal of the operation control system.
The working principle of the invention is as follows: when the indoor air quality control system works, firstly, an inflammation factor sampling detection result is obtained by the inflammation factor sampling detector and the obtained result is output to the early warning processing system; the early warning processing system judges the data after receiving the inflammatory factor sampling detection result, when the data of the inflammatory factor sampling detection result exceeds a set value, the situation that pollutants exceed the standard exists in the indoor environment at the moment is represented, the early warning processing system outputs a signal to a user interface, the user interface sends out early warning information that the pollutants exceed the standard, related personnel are automatically notified to detect and process the indoor pollutants, and after the indoor pollutants are processed, the inflammatory factor sampling detector acquires the inflammatory factor sampling detection result again until the numerical value of the inflammatory factor sampling detection result is smaller than the set value.
When the early warning processing system detects that the value of the inflammatory factor sampling detection result is smaller than a set value, the concentration of indoor pollutants is in an allowable range at the moment, the early warning processing system sends a control signal to a TRP protein expression quantity sampling detector, so that the TRP protein expression quantity sampling detector collects human tissue fluid to obtain TRP protein expression quantity, and converts the TRP protein expression quantity into a corresponding neural electric pulse signal Si, the neural electric pulse signal Si is a neural electric pulse signal expression quantity influenced by the comprehensive action of temperature and pollutants, and a skin temperature sensor collects a human skin temperature value Tskin; according to a human skin temperature value Tskin acquired by a skin temperature sensor, searching and obtaining a standard neuroelectric pulse signal S0 at the temperature, wherein the S0 value is a neuroelectric pulse signal expression quantity only influenced by the temperature; then, calculating the obtained neural electric pulse signal Si and a standard neural electric pulse signal S0 to obtain an operation control signal R; the operation control system adjusts the combined working mode of the fresh air purification system and the dehumidification system according to the numerical range of the operation control signal R, so that the adjustment of the combined working mode of the fresh air purification system and the dehumidification system comprehensively reflects the influence of the indoor environment parameters on the comfort and health of the human body and the energy-saving requirement, the fresh air purification system and the dehumidification system comprehensively adjust the environmental factors comprehensively influencing the comfort and health of the human body under the energy-saving requirement, the adjustment mode comprehensively reflects the characteristic of the influence of the indoor environment parameters on the comfort and health of the human body, and the generation of sick building syndrome is solved.
In the invention, the human biochemical indexes comprise protein channel expression quantity of a temperature receptor TRP (transient receptor potential) and inflammatory factors IL-4, IL-1 beta, IgE and the like; among them, the Transient Receptor Potential (TRP) channel is a kind of cation channel protein widely distributed in peripheral and central nervous systems, including but not limited to TRPA1, TRPM8, TRPV1, TRPV2, TRPV3, TRPV4, etc., among which the earliest discoverers of TRPA1 and TRPM8 have gained 2021 year biological or medical sobel prize and have received international attention. Recently, researches show that the TRP protein expression of a temperature sensor is influenced by the comprehensive action of temperature, humidity and pollutants and can be used as a biological mechanism index of human body comfort, inflammatory factors such as IL-4, IL-1 beta, IgE and the like can be used as biological mechanism indexes of human body health degree, and the biological mechanism indexes form a potential indoor air quality regulation index basis, so the scheme converts the obtained TRP protein expression into corresponding nerve electric pulse signals by comprehensively considering the factors, further outputs the nerve electric pulse signals to an operation control system, and controls a fresh air purification system and a dehumidification system by using the operation control system, therefore, the combined control of the fresh air purification system and the dehumidification system by the operation control system can more meet the requirement of human body on indoor environment comfort, and can more comprehensively reflect the characteristic that a plurality of indoor environment parameters influence the human body comfort health, thereby solving the generation of sick building syndrome.
As shown in fig. 2, a method for controlling indoor air quality based on TRP biochemical indicator detection, which samples the above-mentioned indoor air quality control system based on TRP biochemical indicator detection, includes the following steps:
step 1) an inflammatory factor sampling detector acquires an inflammatory factor sampling detection result and outputs the result to an early warning processing system;
step 2) the early warning processing system judges the inflammatory factor sampling detection result, and executes step 3) when the inflammatory factor sampling detection result exceeds a set value, and executes step 4) when the inflammatory factor sampling detection result does not exceed the set value;
step 3), the user interface sends out early warning information that the pollutants exceed the standard;
step 4) collecting human tissue fluid by using a TRP protein expression quantity sampling detector to obtain a TRP protein expression quantity and detecting the TRP protein expression quantity to obtain a corresponding neural electric pulse signal Si (the Si value at the moment is the neural electric pulse signal expression quantity influenced by the comprehensive action of temperature and pollutants), wherein an air humidity sensor is used for collecting an air humidity value RH, and a skin temperature sensor is used for collecting a human skin temperature value Tskin;
step 5) searching to obtain a standard neuroelectric pulse signal S0 at the temperature according to the human skin temperature value Tskin acquired by the skin temperature sensor (the S0 value at this time is the expression quantity of the neuroelectric pulse signal only affected by the temperature, and the standard value of S0 can be searched according to the attached figure 3);
step 6) the operation control system calculates to obtain an operation control signal R according to the data obtained in the step 4) and the step 5), specifically, the influence of indoor environmental pollutants on the human body is represented or reflected according to the calculated operation control signal R, and different numerical ranges of the operation control signal R can represent the influence degree of the human body health state on the indoor pollutants;
step 7) the operation control system adjusts the combined working mode of the fresh air purification system and the dehumidification system according to the numerical range of the operation control signal R, and different numerical ranges of the operation control signal R can represent the influence degree of the human health state by indoor pollutants, so that the operation control signal R can be used as a basis for adjusting the fresh air purification system and the dehumidification system;
step 8) returns to execute step 1).
In the control method, the comprehensive control of the indoor environmental quality is realized by using the human body biochemical indexes including the protein channel expression quantity of a temperature receptor TRP (transient receptor potential) and the parameters of inflammatory factors IL-4, IL-1 beta, IgE and the like; the temperature sensor TRP (transient receptor potential) channel is a cation channel protein which is widely distributed in the peripheral and central nervous systems, researches show that the expression quantity of the TRP channel is influenced by the comprehensive action of temperature, humidity and pollutants and can be used as a bio-mechanistic index of human body comfort, inflammatory factors such as IL-4, IL-1 beta, IgE and the like can be used as a bio-mechanistic index of human body health degree, and the inflammatory factors form a potential indoor air quality regulation index basis, so that the control method of the scheme can comprehensively reflect the characteristic that indoor environment parameters influence human body comfort and health by comprehensively considering the factors, and the generation of sick building syndrome is solved.
In this embodiment, in step 6), the operation control signal R indicates the magnitude of the influence of the non-thermal environmental factors on the health status of the human body, and the operation control signal R is a dimensionless constant excluding the influence of thermal stress on the expression level of the TRP protein, and is calculated as follows:
thus, the operation control signal R is a dimensionless constant after the influence of thermal stress on the TRP protein expression quantity is eliminated, the numerical characteristics of the operation control signal R reflect the influence of air pollutants and humidity outside the thermal environment on the human body, and the influence of non-thermal environment factors on the health state of the human body is indicated.
When R is less than 1, the comprehensive stimulation of the indoor environment to the human body is small, and the human body state is good, so that the load of an indoor air quality control system can be properly reduced; when R is more than 1, the human body is not only stimulated by temperature, but also obviously stimulated by pollutants and the like, and the operation level of an indoor air quality control system needs to be improved, so that the stimulation amount of pollution factors is reduced.
In this embodiment, in step 7), the combined operation mode of the fresh air purification system and the dehumidification system is as follows:
the fresh air purification system and the dehumidification system are both started;
or the fresh air purification system and the dehumidification system are both closed;
or the dehumidification system is started, and the fresh air purification system is closed;
or the dehumidification system is closed and the fresh air purification system is opened.
Like this, new trend clean system and dehumidification system can work under the mode of difference according to the different value ranges of operation control signal R, adopts the dehumidification system that the energy consumption is lower and the life-span is longer through preferred multiple frequency, and then realizes the optimal control to indoor environmental quality under energy-conserving requirement.
In this embodiment, in step 7),
when R is more than or equal to 1+ X, the human health state is greatly influenced by indoor pollutants, and the fresh air purification system and the dehumidification system are required to be started at the moment so as to reduce the influence of the indoor pollutants on the human health; and the larger the value of R is, the larger the air handling capacity Q or the operating power W of the fresh air purification system needs to be, the value is adjusted according to the following formula in the rated range,
Q＝R n Q O
W＝R m W O ；
when R is less than 1-Y, the human health state is hardly influenced by indoor pollutants, and the fresh air purification system and the dehumidification system are both closed;
when 1-Y is less than or equal to R<When the ratio is 1+ X, the influence of indoor pollutants on the health state of the human body is small, and when RH is more than or equal to RH o When the fresh air purification system is started, the dehumidification system is started, and the fresh air purification system is closed; when RH is equal to<RH o When the dehumidification system is closed, the fresh air is purifiedThe system is started and operates according to the minimum air handling capacity and power, and the measures can effectively slow down the influence of pollutants and meet the requirement of human bodies on the indoor environment;
in the formula: m and n are constants, Q o Is the minimum air handling capacity, W, of the fresh air purification system o Is the minimum operating power of the fresh air purification system, and is selected according to the maximum value when the calculated value of the air handling capacity Q or the operating power W of the fresh air purification system exceeds the rated range, X and Y are constants with the value range of 0.1-1.0, RH o The value range is 30-80%, preferably 50% for the preset constant value.
In this embodiment, in step 1), the inflammation factor sampling detector obtains the inflammation factor sampling result in an invasive or non-invasive manner.
In the embodiment, the inflammation factor sampling detector obtains an inflammation factor sampling result by detecting blood, exhaled air, saliva, skin sweat or urine of a human body.
Therefore, when the inflammatory factors are sampled, the invasive sampling method can be adopted to sample the blood of the human body, and the data obtained by the invasive sampling method is more accurate; the noninvasive sampling method can be adopted to sample tissue fluid such as respiratory exhaust, saliva, skin sweat, urine fluid and the like of a human body, the noninvasive sampling mode is simpler and more convenient to operate, and when the noninvasive sampling method is specifically adopted, the inflammatory factor sampling detector can be arranged near a panel of an air purification system and a dehumidification system or on a certain position of a remote controller or even a toilet of the air purification system and the dehumidification system, so that the sampling detection is convenient.
In this embodiment, in step 1), the inflammatory factor sampling result obtained by the inflammatory factor sampling detector includes IL-4, IL-1 β and IgE.
Therefore, the collection of the parameters can better reflect the influence condition of indoor pollutants on human bodies, and data basis is provided for the adjustment of indoor air quality.
In this embodiment, in step 3), step 1) is executed again after the detection processing is performed on the pollutant.
Therefore, when the concentration of the indoor pollutants exceeds the standard, the concentration of the indoor pollutants can be always below an allowable value by processing the pollutants and then detecting the sampling result of the inflammatory factors again.
In this embodiment, the TRP protein expression quantity sampling detector collects tissue fluid of a human body, obtains a relative expression quantity mrna (TRPs) of the TRP protein expression quantity of the human body according to the collected data, and then converts the relative expression quantity mrna (TRPs) into a corresponding neural electric pulse signal Si (sub/sec) for expression.
Compared with the prior art, the indoor air quality control method and system based on TRP biochemical index detection provided by the invention utilize essential mechanism indexes of inflammatory factors IL-4, IL-1 beta, IgE and the like of a human body influenced by an air quality environment and the characteristic that the expression quantity of a TRP channel of a human body temperature receptor is influenced by the comprehensive action of temperature and pollutants, and the method and the system can be used as a biological mechanism index of the influence degree of the human body health comfort and the air quality environment and used as a new index basis for indoor air quality control, so that the indoor air environment control strategy level and efficiency are improved. Experiments prove that compared with the traditional control method, the control method disclosed by the invention has the advantages that the air quality environmental factors influencing the comfort and health of a human body are adjusted more comprehensively and accurately, and the health and comfort degree of the indoor air environment created according to the adjustment and control method is greatly improved, so that the generation of sick building syndrome can be effectively solved.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the technical solutions, and those skilled in the art should understand that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions, and all that should be covered by the claims of the present invention.
Claims (8)
1. An indoor air quality control system based on TRP biochemical index detection is characterized by comprising an inflammation factor sampling detector, an early warning processing system, a user interface, a TRP protein expression quantity sampling detector, a skin temperature sensor, an air humidity sensor, an operation control system, a fresh air purification system and a dehumidification system;
the output end of the inflammation factor sampling detector is in data connection with the input end of the early warning processing system and is used for detecting inflammation factor data and outputting the inflammation factor data to the early warning processing system;
the output end of the early warning processing system is respectively in data connection with the input end of the user interface and the input end of the TRP protein expression quantity sampling detector, and is used for outputting an early warning signal to the user interface when the inflammation factor data exceeds a set value and outputting a signal to the TRP protein expression quantity sampling detector when the inflammation factor data does not exceed the set value;
the output end of the TRP protein expression quantity sampling detector is in data connection with the input end of the operation control system and is used for obtaining the TRP protein expression quantity and converting the TRP protein expression quantity into a corresponding nerve electric pulse signal to be output to the operation control system;
the output end of the skin temperature sensor is in data connection with the input end of the operation control system and is used for collecting a human skin temperature value and outputting the human skin temperature value to the operation control system;
the output end of the air humidity sensor is in data connection with the input end of the operation control system and is used for collecting an air humidity value RH and outputting the air humidity value RH to the operation control system;
the output end of the operation control system is respectively in data connection with the input end of the fresh air purification system and the input end of the dehumidification system and is used for outputting corresponding control signals to the fresh air purification system and the dehumidification system according to data information of each input end of the operation control system;
the fresh air purification system is used for controlling the operation of the fresh air system and the purification system according to the control signal of the operation control system;
the TRP protein expression quantity sampling detector collects human tissue fluid to obtain TRP protein expression quantity and detects the TRP protein expression quantity to obtain corresponding nerve electric pulse signals Si, the skin temperature sensor collects human skin temperature values Tskin, standard nerve electric pulse signals S0 at the temperature are obtained through searching according to the human skin temperature values Tskin collected by the skin temperature sensor, an arithmetic control system calculates to obtain arithmetic control signals according to the obtained data, the numerical value of the arithmetic control signals is represented by a non-dimensionalized TRP protein expression quantity ratio R, and the arithmetic control system adjusts the combined working mode of the fresh air purification system and the dehumidification system according to the numerical range of the arithmetic control signals R.
2. An indoor air quality control method based on TRP biochemical index detection is characterized in that the indoor air quality control system based on TRP biochemical index detection as claimed in claim 1 is sampled, and the method comprises the following steps:
step 1) the inflammation factor sampling detector obtains an inflammation factor sampling detection result and outputs the result to the early warning processing system, wherein the inflammation factor sampling result obtained by the inflammation factor sampling detector comprises IL-4, IL-1 beta and IgE;
step 2) the early warning processing system judges the inflammatory factor sampling detection result, and executes step 3) when the inflammatory factor sampling detection result exceeds a set value and executes step 4) when the inflammatory factor sampling detection result does not exceed the set value;
step 3), the user interface sends out early warning information that pollutants exceed the standard;
step 4) the TRP protein expression quantity sampling detector collects human tissue fluid to obtain human TRP protein expression quantity and detects the human TRP protein expression quantity to obtain corresponding nerve electric pulse signals Si, the air humidity sensor is used for collecting an air humidity value RH, meanwhile, the skin temperature sensor collects a human skin temperature value Tskin, and the TRP protein expression quantity comprises TRPA1, TRPM8, TRPV1, TRPV2, TRPV3 and TRPV 4;
step 5) searching to obtain a standard neuroelectric pulse signal S0 at the temperature according to the human skin temperature value Tskin acquired by the skin temperature sensor;
step 6), the operation control system calculates to obtain an operation control signal according to the data obtained in the step 4) and the step 5), wherein the value of the operation control signal is a non-dimensionalized TRP protein expression ratio R;
step 7), the operation control system adjusts the combined working mode of the fresh air purification system and the dehumidification system according to the numerical range of the operation control signal R;
step 8) returns to execute step 1).
3. The indoor air quality control method based on TRP biochemical index detection according to claim 2, wherein in step 6), the operation control signal is based on a nondimensional TRP protein expression ratio R, and the value of R can be calculated as follows:
4. the indoor air quality control method based on TRP biochemical index detection as claimed in claim 2, wherein in step 7), the combined working mode of the fresh air purification system and the dehumidification system is as follows:
the fresh air purification system and the dehumidification system are both started;
or the fresh air purification system and the dehumidification system are both closed;
or the dehumidification system is started, and the fresh air purification system is closed
Or the dehumidification system is closed and the fresh air purification system is opened.
5. The indoor air quality control method based on TRP biochemical index detection according to claim 4, wherein in step 7),
when R is more than or equal to 1+ X, the fresh air purification system and the dehumidification system are both started, and the air handling capacity Q or the operating power W of the fresh air purification system is regulated within a rated range according to the following formula:
Q＝R n Q O
W＝R m W O ；
when R is less than 1-Y, the fresh air purification system and the dehumidification system are both closed;
when 1-Y is less than or equal to R<1+ X, and RH is greater than or equal to RH o When the fresh air purification system is started, the dehumidification system is started, and the fresh air purification system is closed;
when 1-Y is less than or equal to R<1+ X, and RH<RH o When the system is in use, the dehumidification system is closed, the fresh air purification system is opened, and the system is operated according to the lowest air handling capacity and power;
in the formula: m and n are constants, Q o Is the minimum air handling capacity, W, of the fresh air purification system o Is the minimum operating power of the fresh air purification system, and is selected according to the maximum value when the calculated value of the air handling capacity Q or the operating power W of the fresh air purification system exceeds the rated range, X and Y are constants with the value range of 0.1-1.0, RH o The value is a preset constant value and the value range is 30-80%.
6. The indoor air quality control method based on TRP biochemical index detection according to claim 2, wherein in step 1), the inflammation factor sampling detector obtains the inflammation factor sampling result in an invasive or non-invasive manner.
7. The indoor air quality control method based on TRP biochemical index detection according to claim 6, wherein the inflammation factor sampling detector obtains an inflammation factor sampling result through detection of human blood, exhaled air, saliva, skin sweat or urine.
8. The indoor air quality control method based on TRP biochemical index detection according to claim 2, wherein in the step 3), the step 1) is executed after the pollutant is detected and treated.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| HUP0100241A2 (en) * | 1998-01-23 | 2001-06-28 | National Jewish Medical And Research Center | Method for treating inflammatory diseases using heat shock proteins |
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| US9463339B2 (en) * | 2009-11-04 | 2016-10-11 | Atsuo Nozaki | Cleaning filter, air cleaning device using same, and air cleaning maintenance system |
| US20120183949A1 (en) * | 2011-01-19 | 2012-07-19 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Method, device, or system using lung sensor for detecting a physiological condition in a vertebrate subject |
| US20140336159A1 (en) * | 2011-10-07 | 2014-11-13 | Pulmatrix, Inc. | Methods for treating and diagnosing respiratory tract infections |
| CN102519126A (en) * | 2012-01-12 | 2012-06-27 | 北京汇丰隆经济技术开发有限公司 | Air quality real-time detecting and protecting system |
| CN104456841B (en) * | 2014-11-13 | 2017-01-25 | 重庆大学 | Thermal and humid environment integrated control air-conditioning system and method based on thermal comfort evaluation |
| EP3253282A4 (en) * | 2015-02-05 | 2018-09-26 | Mc10, Inc. | Method and system for interacting with an environment |
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| CN104990212B (en) * | 2015-06-30 | 2018-01-02 | 广东乐心医疗电子股份有限公司 | Method and system for intelligently regulating and controlling air conditioner |
| WO2017028813A1 (en) * | 2015-08-19 | 2017-02-23 | Lin Xu | A composition for reducing lung and/or systemic inflammation associated with pm2.5 exposure and the use thereof |
| WO2017062508A1 (en) * | 2015-10-05 | 2017-04-13 | Mc10, Inc. | Method and System for Neuromodulation and Stimulation |
| CN106352509A (en) * | 2016-11-20 | 2017-01-25 | 广西大学 | Smart air conditioning system and the application thereof |
| CN108679797A (en) * | 2018-07-19 | 2018-10-19 | 珠海格力电器股份有限公司 | A kind of air conditioning control method and system |
| CN211243748U (en) * | 2019-12-11 | 2020-08-14 | 河南温迪生物科技研究院有限公司 | A quick no wound nasal mucus sampling box for experimental study |
| CN214750166U (en) * | 2021-05-07 | 2021-11-16 | 深圳市众安腾达科技有限公司 | Automobile toxic and harmful gas detector |
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