CN114002075B - Artificial blood vessel compliance testing device - Google Patents

Artificial blood vessel compliance testing device Download PDF

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Publication number
CN114002075B
CN114002075B CN202111275539.4A CN202111275539A CN114002075B CN 114002075 B CN114002075 B CN 114002075B CN 202111275539 A CN202111275539 A CN 202111275539A CN 114002075 B CN114002075 B CN 114002075B
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Prior art keywords
blood vessel
artificial blood
adjusting
bottom plate
rear support
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CN114002075A (en
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赵荟菁
伊光辉
孟凯
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Suzhou University
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Suzhou University
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N3/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N3/08Investigating strength properties of solid materials by application of mechanical stress by applying steady tensile or compressive forces
    • G01N3/10Investigating strength properties of solid materials by application of mechanical stress by applying steady tensile or compressive forces generated by pneumatic or hydraulic pressure
    • G01N3/12Pressure testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N3/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N3/02Details
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N3/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N3/02Details
    • G01N3/06Special adaptations of indicating or recording means
    • G01N3/068Special adaptations of indicating or recording means with optical indicating or recording means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0001Type of application of the stress
    • G01N2203/0003Steady
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0014Type of force applied
    • G01N2203/0016Tensile or compressive
    • G01N2203/0019Compressive
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/003Generation of the force
    • G01N2203/0042Pneumatic or hydraulic means
    • G01N2203/0048Hydraulic means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/02Details not specific for a particular testing method
    • G01N2203/025Geometry of the test
    • G01N2203/0258Non axial, i.e. the forces not being applied along an axis of symmetry of the specimen
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/02Details not specific for a particular testing method
    • G01N2203/026Specifications of the specimen
    • G01N2203/0262Shape of the specimen
    • G01N2203/0274Tubular or ring-shaped specimens
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/02Details not specific for a particular testing method
    • G01N2203/06Indicating or recording means; Sensing means
    • G01N2203/0641Indicating or recording means; Sensing means using optical, X-ray, ultraviolet, infrared or similar detectors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/02Details not specific for a particular testing method
    • G01N2203/06Indicating or recording means; Sensing means
    • G01N2203/067Parameter measured for estimating the property
    • G01N2203/0676Force, weight, load, energy, speed or acceleration
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/02Details not specific for a particular testing method
    • G01N2203/06Indicating or recording means; Sensing means
    • G01N2203/067Parameter measured for estimating the property
    • G01N2203/0682Spatial dimension, e.g. length, area, angle

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Prostheses (AREA)

Abstract

The embodiment of the application provides an artificial blood vessel compliance testing device which comprises a fixing device, a circulating water component and a signal processing component, wherein the fixing device comprises a fixing seat, a front support and a rear support, the fixing seat comprises a bottom plate and a plurality of pairs of side plates, an artificial blood vessel is fixed between the front support and the rear support, a flow-around roller is optionally arranged on the bottom plate, so that the artificial blood vessel can optionally pass through the flow-around roller or not, and the circulating water component is used for conveying circulating water to the artificial blood vessel; the signal processing component is configured to obtain artificial blood vessel compliance data according to the pressure information and the radial displacement information, and the flow-around rollers are optionally arranged on the bottom plate to meet the requirements of artificial blood vessel compliance testing under the requirements of straight lines or different curvatures.

Description

Artificial blood vessel compliance testing device
Technical Field
The application relates to a flexible material testing instrument, in particular to an artificial blood vessel compliance testing device.
Background
The human artery has viscoelastic property, plays an important role in the function of cardiac vessels, and when the heart contracts, the vessels are full, the vessel wall expands, and the expansibility plays an important role in stabilizing blood. The compliance of an artificial blood vessel refers to the deformation responsiveness of the artificial blood vessel to the internal stress of the duct, and the compliance plays an important role in the transplantation complications, especially at the anastomosis. With the increase of in vivo implantation time, the compliance of the implanted blood vessel is reduced to 1/3 of the original value along with the proliferation of fibrous tissues, the probability of thrombus occurrence in the inner cavity is increased due to the compliance loss, the new inner cavity is thickened, and arteriosclerosis is formed at the tail end of the blood vessel, so that the measurement and matching of the compliance are important problems in the biomechanical performance of the artificial blood vessel.
In the prior art, for example YY-0500-2004/ISO7198 is generally used; the simple device shown in 1998 is used for detection, but in practice, it is difficult to detect the artificial blood vessel by the existing device when the artificial blood vessel needs to be in a curved shape or the like.
Disclosure of Invention
In view of the above-mentioned shortcomings of the prior art, the present application provides an artificial blood vessel compliance testing device to solve the above-mentioned technical problems.
The artificial blood vessel compliance testing device comprises a fixing device, a circulating water component and a signal processing component:
the fixing device comprises a fixing seat, a front support and a rear support, wherein the fixing seat comprises a bottom plate and a plurality of pairs of side plates, wherein the bottom plate is provided with a containing space in a surrounding mode, the side plates are oppositely arranged on the periphery of the bottom plate, the front support and the rear support are respectively arranged on one pair of side plates, an artificial blood vessel is fixed between the front support and the rear support and passes through the containing space, a flow-around roller is also optionally arranged on the bottom plate, when the flow-around roller is arranged on the bottom plate, the artificial blood vessel passes through the flow-around roller, and when the flow-around roller is not arranged on the bottom plate, the artificial blood vessel does not pass through the flow-around roller;
the circulating water assembly is used for conveying circulating water to the artificial blood vessel;
the signal processing assembly comprises a pressure sensor, a laser displacement sensor and a signal processing assembly, wherein the pressure sensor is arranged on a front support and a rear support and used for acquiring pressure information, the laser displacement sensor is arranged on a fixing device and used for acquiring radial displacement information of an artificial blood vessel, the signal processing assembly is connected with the pressure sensor and the laser displacement sensor, and the signal processing assembly is configured to acquire compliance data of the artificial blood vessel according to the pressure information and the radial displacement information.
Further, the bottom plate on be provided with a plurality of connecting holes, the winding roller include roll body and link, wherein, the link be configured to can insert and establish in the connecting hole, signal processing subassembly include the mount pad, laser displacement sensor set up on the mount pad, the mount pad include the installation end, the installation end fix in the connecting hole.
Further, the pair of side plates comprises a first side plate and a second side plate, the front support is arranged on the first side plate, the rear support is arranged on the second side plate, the fixing seat is further provided with an adjusting device, the adjusting device comprises a first adjusting piece and a second adjusting piece, the first adjusting piece is configured to adjust the position of the front support in the vertical direction, and the second adjusting piece is configured to adjust the position of the rear support in the horizontal direction.
Further, a first adjusting groove is formed in the first side plate, the front support is arranged in the first adjusting groove, and the position of the front support in the height direction of the first adjusting groove is limited by the first adjusting piece in a movable mode.
Further, a third adjusting hole is formed in the second side plate, the rear support is arranged in the third adjusting hole, and the second adjusting piece can movably limit the position of the rear support in the horizontal direction of the third adjusting hole.
Further, still be provided with the fourth regulating groove in the top of third regulation hole, the length in fourth regulating groove equals with the length in third regulation hole, and, the fourth regulating groove extends to the third regulation hole from the top surface of second curb plate, the second regulating part include that one end stretches out the top surface, the other end is connected and the montant of holding in the fourth regulating groove with the back support, the one end that the montant stretched out the top surface be provided with the screw thread to there is the nut through threaded connection.
Further, the bottom plate is in a regular polygon shape with even sides, and the logarithm of the side plate is 1/2 of the number of the sides of the bottom plate.
Further, the mount pad include the extension board that a pair of interval set up, the artificial blood vessel wear to establish between the extension board that a pair of interval set up, laser displacement sensor including the transmitting end that is used for transmitting the light beam and the receiving end of receiving light beam, wherein, transmitting end and receiving end set up respectively on a pair of extension board, the artificial blood vessel is perpendicular through the light beam plane that laser displacement sensor transmitting end sent.
Further, at least a portion of the contour projected by the at least one wrap roller on the base plate is an involute.
The beneficial effects are that: the embodiment of the application provides an artificial blood vessel compliance testing device which comprises a fixing device, a circulating water component and a signal processing component, wherein the fixing device comprises a fixing seat, a front support and a rear support, the fixing seat comprises a bottom plate and a plurality of pairs of side plates, an artificial blood vessel is fixed between the front support and the rear support, a flow-around roller is optionally arranged on the bottom plate, so that the artificial blood vessel can optionally pass through the flow-around roller or not, and the circulating water component is used for conveying circulating water to the artificial blood vessel; the signal processing component is configured to obtain artificial blood vessel compliance data according to the pressure information and the radial displacement information, and the flow-around rollers are optionally arranged on the bottom plate to meet the requirements of artificial blood vessel compliance testing under the requirements of straight lines or different curvatures.
Drawings
FIG. 1 is a schematic diagram of an artificial blood vessel compliance testing device of the present application;
FIG. 2 is a schematic view of the fixing device in FIG. 1;
FIG. 3 is a schematic view of an artificial blood vessel passing through a flow-around roller;
fig. 4 is a schematic view of the projection profile of the flow roller on the base plate in another embodiment.
Graphic symbol description:
a fixing device 10; the accommodating space 100; a bottom plate 101; a side plate 102; a first regulating groove 103; a second adjustment slot 104; a third adjustment aperture 105; a fourth adjustment slot 106; a front support 11; a front three-way valve 111; a pre-pressing tube 112; a front connector 113; a rear support 12; a rear three-way valve 121; a connection pipe 122; a rear connector 123; a mounting base 13; a connection hole 15; the wrap rollers 151, 251; a second regulating member 142; peristaltic pump 20; a circulation water tank 30; a signal processing unit 50; a computer 60; a pressure sensor 71; a laser displacement sensor 72; and a vascular prosthesis 80.
Detailed Description
The present application will be described in further detail with reference to examples. It is specifically noted that the following examples are only for illustrating the present application, but do not limit the scope of the present application. Likewise, the following examples are only some, but not all, of the examples of the present application, and all other examples, which a person of ordinary skill in the art would obtain without making any inventive effort, are within the scope of the present application.
In the description of the present application, it should be noted that the terms "first," "second," and the like are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implying a number of technical features which is being indicated. Thus, a feature defining "a first", "a second", etc. may explicitly or implicitly include one or more such feature.
Referring to fig. 1-3, an embodiment of the present application provides an artificial blood vessel 80 compliance testing device, which includes a fixing device 10, a circulating water component and a signal processing component.
The fixing device 10 is used for fixing an artificial blood vessel 80, and comprises a fixing seat, a front support 11 and a rear support 12 which are arranged on the fixing seat, wherein the artificial blood vessel 80 is fixed between the front support 11 and the rear support 12.
The fixing seat comprises a bottom plate 101 and a plurality of pairs of side plates 102 arranged on the periphery of the bottom plate 101, the bottom plate 101 and the side plates 102 are enclosed to form an open accommodating space 100, a pair of front supports 11 and rear supports 12 are respectively arranged on the side plates 102, the front supports 11 comprise a front three-way valve 111, a pre-pressing pipe 112 and a front connector 113 which are sequentially arranged, the rear supports 12 comprise a rear three-way valve 121, a connecting pipe 122 and a rear connector 123 which are sequentially arranged, the front connector 113 and the rear connector 123 are respectively used for connecting two ends of an artificial blood vessel 80, and the artificial blood vessel 80 passes through the accommodating space 100.
Preferably, the side plates 102 disposed at the periphery of the bottom plate 101 are sequentially connected, so that each side plate 102 forms a complete ring shape.
In one embodiment, the pair of side plates 102 includes a first side plate and a second side plate, the front support 11 is disposed on the first side plate, and the rear support 12 is disposed on the second side plate.
Preferably, the bottom plate 101 has an even number of regular polygon, so that side plates 102 with 1/2 of the number of the regular polygon are arranged along the periphery of the bottom plate 101, and the front support 11 and the rear support 12 are arranged on the side plates 102 in corresponding numbers, so that the artificial blood vessels 80 with different diameters can be conveniently tested.
Preferably, the bottom plate 101 is a regular hexagon, and three sets of front support 11 and rear support 12 are provided for adapting to the artificial blood vessel 80 with the size of 4mm, 5mm and 6 mm.
The base plate 101 is optionally further provided with a winding roller 151, so that the artificial blood vessel 80 optionally passes through the winding roller 151 or does not pass through the winding roller 151, specifically, in this embodiment, the base plate 101 is provided with a plurality of connection holes 15, and the winding roller 151 includes a roller body and a connection end, where the connection end is configured to be inserted into the connection hole 15, it is understood that a projection of a connection line between the front connector 113 and the rear connector 123 on the base plate 101 and a projection of at least one winding roller 151 on the base plate 101 form a cross, in this case, when the artificial blood vessel 80 is disposed between the front connector 113 and the rear connector 123, there must be at least one winding roller 151 to block the artificial blood vessel 80, so that the artificial blood vessel 80 needs to bypass the winding roller 151, so that the artificial blood vessel 80 forms a bend at the winding roller 151, and at the same time, when the winding roller 151 is not inserted into all connection holes 15, or at least when the connection line between the front connector 113 and the rear connector 123 is not inserted into the winding roller 151, the artificial blood vessel 80 forms a straight line.
It will be appreciated that when the plurality of connection holes 15 provided in the base plate 101 are arranged in a predetermined pattern, the artificial blood vessel 80 provided between the front connector 113 and the rear connector 123 will be curved in a predetermined pattern.
It will be appreciated that when the wrap rollers 151 are provided with different diameters, the vascular prosthesis 80 will form a curved configuration of different curvatures.
Preferably, the connection holes 15 are formed in an array on the bottom plate 101.
Referring to fig. 4, in a preferred embodiment, at least a portion of the contour of the circumferential roller 251 projected on the base plate 101 is involute, in which case, different curvature requirements of the vascular prosthesis 80 can be satisfied by one circumferential roller 151.
Further, the fixing base is further provided with an adjusting device for adjusting the shape of the artificial blood vessel 80 in the accommodating space 100, specifically, the adjusting device includes a first adjusting member and a second adjusting member 142, where the first adjusting member is configured to adjust the position of the front support 11 in the vertical direction, and the second adjusting member 142 is configured to adjust the position of the rear support 12 in the horizontal direction, and of course, in other embodiments, it may also be provided that the first adjusting member adjusts the position of the front support 11 in the horizontal direction or adjusts the position of the front support 11 in the vertical direction or adjusts the position of the rear support 12 in the horizontal direction at the same time, and the second adjusting member 142 adjusts the position of the rear support 12 in the horizontal direction or adjusts the position of the rear support 12 in the horizontal direction at the same time, and it is understood that when the position of the front support 11 changes in the vertical direction, the front end of the artificial blood vessel 80 connected between the front support 11 and the rear support 12 changes in the vertical direction, so that the shape of the artificial blood vessel 80 in the accommodating space 100 changes, especially when the artificial blood vessel 80 winds around the flow roller 151, and the shape changes in the same horizontal direction when the rear support 12 changes in the horizontal direction.
Specifically, in this embodiment, the first side plate 102 is provided with a first adjusting groove 103, the front support 11 is disposed in the first adjusting groove 103, and the first adjusting member movably defines a position of the front support 11 in the height direction of the first adjusting groove 103, so as to adjust a position of the front support 11 in the vertical direction.
In one embodiment, the first adjusting member is a bolt, the bolt is inserted into a vertical screw hole, and the front end of the bolt is connected to the front support 11, and when the bolt is turned, the front end of the bolt moves in the vertical direction and the front support 11 moves in the vertical direction.
In this embodiment, a second adjusting groove 104 is further disposed below the first adjusting groove 103, the length direction of the second adjusting groove 104 is parallel to the vertical direction, and an opening facing the outside is formed, the first adjusting member includes a vertical supporting member accommodated in the second adjusting groove 104 and a horizontal supporting member perpendicular to the vertical supporting member, one end of the horizontal supporting member extends out of the opening of the second adjusting groove 104 in the horizontal direction, the other end of the horizontal supporting member is connected to the vertical supporting member, a nut is disposed at one end of the horizontal supporting member extending out of the second adjusting groove 104 and is connected to the horizontal supporting member in a threaded manner, when the height of the front support 11 in the vertical direction needs to be adjusted, the nut is loosened, the horizontal supporting member moves along the length direction of the second adjusting groove 104 under the action of an external force, so that the front support 11 moves in the vertical direction, and when the front support 11 is adjusted to a predetermined position, the position of the horizontal supporting member is fixed, and therefore the position of the front support 11 is fixed.
Preferably, the first adjusting groove 103 is an open groove, and the opening direction of the first adjusting groove 103 faces the vertical direction.
The second side plate 102 is provided with a third adjusting hole 105, the rear support 12 is disposed in the third adjusting hole 105, and the second adjusting member 142 movably defines the position of the rear support 12 in the horizontal direction of the third adjusting hole 105, so as to adjust the position of the rear support 12 in the horizontal direction.
It can be appreciated that the third adjusting hole 105 includes a length direction, the length direction of the third adjusting hole 105 is parallel to the horizontal direction, and the third adjusting hole 105 penetrates through the thickness direction of the second side plate 102.
In this embodiment, a fourth adjusting slot 106 is further disposed above the third adjusting hole 105, the length of the fourth adjusting slot 106 is equal to that of the third adjusting hole 105, and the fourth adjusting slot 106 extends from the top surface of the second side plate 102 to the third adjusting hole 105, the second adjusting member 142 includes a vertical rod with one end extending out of the top surface and the other end connected with the rear support 12 and accommodated in the fourth adjusting slot 106, one end of the vertical rod extending out of the top surface is provided with threads and is connected with a nut through threads, when the position of the rear support 12 in the horizontal direction needs to be adjusted, the nut is loosened, the vertical rod moves along the length direction of the fourth adjusting slot 106 under the action of an external force, so that the rear support 12 moves in the horizontal direction, and when the position is adjusted to a predetermined position, the nut is screwed, so that the position of the vertical rod is fixed, and therefore the position of the rear support 12 is fixed.
The circulating water assembly is used for conveying circulating water to the artificial blood vessel 80, and specifically comprises a circulating water tank 30, a peristaltic pump 20 and a connecting pipeline, and it can be understood that the circulating water assembly is in pipeline connection with a front three-way valve 111 and a rear three-way valve 121.
The signal processing assembly comprises a pressure sensor 71 arranged on the three-way valve, a laser displacement sensor 72 arranged on the fixing assembly and a signal processing unit 50 connected with the pressure sensor 71 and the laser displacement sensor 72, wherein the pressure sensor 71 is used for acquiring pressure information, the laser displacement sensor 72 is used for detecting radial displacement information of the artificial blood vessel 80, and the signal processing unit 50 acquires the pressure information and the radial displacement information and acquires compliance data of the artificial blood vessel 80.
Further, the base plate 101 is further provided with an installation seat 13, the laser displacement sensor 72 is disposed on the installation seat 13, in this embodiment, the installation seat 13 includes a pair of support plates disposed at intervals, the artificial blood vessel 80 is disposed between the pair of support plates disposed at intervals, and the laser displacement sensor 72 includes a transmitting end and a receiving end, where the transmitting end and the receiving end are disposed on the pair of support plates respectively.
Further, the mounting base 13 includes a mounting end, and the mounting end is fixed in the connecting hole 15.
That is, in this case, the connection holes 15 may be used to fix the wrap rollers 151 and the mount 13 at the same time, thereby conveniently adjusting the positions of the wrap rollers 151 and the mount 13.
The present application is further described below in connection with a method of testing the compliance of the present vascular prosthesis 80 with the compliance testing device of the present vascular prosthesis 80.
The specific test procedure for testing the compliance of the artificial blood vessel 80 using the test device is as follows:
s1: selecting the caliber and shape of the test artificial blood vessel 80;
the appropriate connection port is selected according to the caliber of the artificial blood vessel 80 to be tested, whether the flow-around roller 151 is used is determined according to the shape required to be tested, if the flow-around roller 151 is not required to be installed in the test of the straight shape, and the position of the flow-around roller is determined according to the requirement in the bent shape.
S2: the device is connected with a circulating water component, a pressure sensor 71, a laser displacement sensor 72 and a signal processing component;
in this embodiment, the tubing connects peristaltic pump 20, circulation tank 30, front three-way valve 111, rear three-way valve 121, and the liquid in circulation tank 30 should not exceed 2/3 of its volume.
The pressure sensor 71 is connected to the three-way valve in a threaded manner, so that the connection is tight, and water leakage is prevented.
The laser displacement sensor 72 is positioned at a predetermined location and the vascular prosthesis 80 is passed between the emitting and receiving ends of the laser displacement sensor 72, it being understood that the location of the laser displacement sensor 72 is adjusted as necessary so that the vascular prosthesis 80 passes perpendicularly through the plane of the light beam emitted by the emitting end of the laser displacement sensor 72.
The pressure sensor 71 and the laser displacement sensor 72 are connected to the signal processing unit 50, and preferably the signal processing unit 50 may be connected to a computer 60 for further processing of the signals.
S3: delivering circulating water to the artificial blood vessel 80 through a circulating water component, acquiring pressure information through a pressure sensor 71, acquiring radial displacement information of the artificial blood vessel 80 through a laser displacement sensor 72, and adjusting the circulating water pressure range to meet YY-0500-2004/ISO7198;1998, the test will be performed at three different sets of high and low pressures, respectively, with low pressures of 50-90mmHg, medium pressures of 80-120mmHg, and high pressures of 110-150mmHg.
S4: obtaining compliance data of the artificial blood vessel 80 according to the pressure information and the radial displacement information;
after the pressure adjustment is stabilized, compliance data of the artificial blood vessel 80 is obtained according to the pressure information and the radial displacement information of the artificial blood vessel 80, and the compliance data is calculated as follows:
a) If the outer diameter is measured directly, then the inner radius is calculated by
Wherein Rp= (Dp/2) -t
Rp—the inner radius after pressurization;
dp—the outer diameter after pressurization;
t-vessel wall thickness;
note that for biological materials the wall thickness varies significantly at different pressures, and if the vessel wall is incompressible, the same value can be used for the wall thickness of the vessel at any pressure.
b) If the volume and length are measured directly, the radius after pressurization must be calculated from the volume and length;
c) Once the inner radius of the prosthesis is calculated at a set of pressures, the radial compliance can be obtained by:
compliance (%) = [ (R) P1 -R P2 )/R P1 (P 1 -P 2 )]×10 4
Wherein:
P 1 low pressure value in mmHg (mmHg)
P 2 High pressure value in mmHg (mmHg)
The radial compliance calculated above is expressed as a percentage of change per 100mmHg diameter.
The foregoing description is only illustrative of the present application and is not intended to limit the scope of the application, and all equivalent structures or equivalent processes or direct or indirect application in other related technical fields are included in the scope of the present application.

Claims (9)

1. An artificial blood vessel compliance testing device comprises a fixing device, a circulating water component and a signal processing component, and is characterized in that,
the fixing device comprises a fixing seat, a front support and a rear support, wherein the fixing seat comprises a bottom plate and a plurality of pairs of side plates, wherein the bottom plate is provided with a containing space in a surrounding mode, the side plates are oppositely arranged on the periphery of the bottom plate, the front support and the rear support are respectively arranged on one pair of side plates, an artificial blood vessel is fixed between the front support and the rear support and passes through the containing space, a flow-around roller is also optionally arranged on the bottom plate, when the flow-around roller is arranged on the bottom plate, the artificial blood vessel passes through the flow-around roller, and when the flow-around roller is not arranged on the bottom plate, the artificial blood vessel does not pass through the flow-around roller;
the circulating water assembly is used for conveying circulating water to the artificial blood vessel;
the signal processing assembly comprises a pressure sensor, a laser displacement sensor and a signal processing assembly, wherein the pressure sensor is arranged on a front support and a rear support and used for acquiring pressure information, the laser displacement sensor is arranged on a fixing device and used for acquiring radial displacement information of an artificial blood vessel, the signal processing assembly is connected with the pressure sensor and the laser displacement sensor, and the signal processing assembly is configured to acquire compliance data of the artificial blood vessel according to the pressure information and the radial displacement information.
2. The artificial blood vessel testing device according to claim 1, wherein the base plate is provided with a plurality of connecting holes, the flow roller comprises a roller body and connecting ends, wherein the connecting ends are configured to be inserted into the connecting holes, the signal processing assembly comprises a mounting seat, the laser displacement sensor is arranged on the mounting seat, the mounting seat comprises a mounting end, and the mounting end is fixed in the connecting holes.
3. The artificial blood vessel testing device according to claim 2, wherein the pair of side plates comprises a first side plate and a second side plate, the front support is arranged on the first side plate, the rear support is arranged on the second side plate, the fixing seat is further provided with an adjusting device, the adjusting device comprises a first adjusting piece and a second adjusting piece, the first adjusting piece is configured to adjust the position of the front support in the vertical direction, and the second adjusting piece is configured to adjust the position of the rear support in the horizontal direction.
4. The artificial blood vessel testing device according to claim 3, wherein the first side plate is provided with a first adjusting groove, the front support is arranged in the first adjusting groove, and the first adjusting piece movably limits the position of the front support in the height direction of the first adjusting groove.
5. The artificial blood vessel testing device according to claim 3, wherein the second side plate is provided with a third adjusting hole, the rear support is arranged in the third adjusting hole, and the second adjusting member movably limits the position of the rear support in the horizontal direction of the third adjusting hole.
6. The artificial blood vessel testing device according to claim 5, wherein a fourth adjusting groove is further provided above the third adjusting hole, the length of the fourth adjusting groove is equal to the length of the third adjusting hole, the fourth adjusting groove extends from the top surface of the second side plate to the third adjusting hole, the second adjusting member comprises a vertical rod with one end extending out of the top surface, the other end connected with the rear support and accommodated in the fourth adjusting groove, and one end of the vertical rod extending out of the top surface is provided with threads and is connected with a nut through the threads.
7. The artificial blood vessel testing device according to claim 1, wherein the bottom plate has a regular polygon shape with even sides, and the number of pairs of the side plates is 1/2 of the number of sides of the bottom plate.
8. The artificial blood vessel testing device according to claim 2, wherein the mounting base comprises a pair of support plates arranged at intervals, the artificial blood vessel is arranged between the pair of support plates arranged at intervals in a penetrating manner, the laser displacement sensor comprises a transmitting end for transmitting light beams and a receiving end for receiving the light beams, wherein the transmitting end and the receiving end are respectively arranged on the pair of support plates, and the artificial blood vessel passes through the plane of the light beams emitted by the transmitting end of the laser displacement sensor perpendicularly.
9. The artificial blood vessel testing device of any one of claims 1-8, wherein at least a portion of the contour of the projection of the at least one wrap roller onto the base plate is an involute.
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Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101393095A (en) * 2008-10-16 2009-03-25 东华大学 Artificial blood vessel compliance emulation test device and test method thereof
JP2009233226A (en) * 2008-03-28 2009-10-15 Yotaro Hatamura Blood vessel shape measuring instrument and vascular compliance measuring method
CN102680324A (en) * 2012-06-01 2012-09-19 苏州大学 Biomechanical property testing method for blood vessel prosthesis and device thereof
CN202814798U (en) * 2012-06-01 2013-03-20 苏州大学 Biomechanical property testing device for artificial blood vessels
CN106604678A (en) * 2014-08-22 2017-04-26 心血管系统股份有限公司 Methods, devices and systems for sensing, measuring and/or characterizing vessel and/or lesion compliance and/or elastance changes during vascular procedures
CN206161438U (en) * 2016-11-02 2017-05-10 郑州大学 Blood vessel organizational project support mechanical properties test system
CN107748128A (en) * 2017-11-27 2018-03-02 郑州大学 The biomechanical property test device and method of a kind of scaffold for vascular tissue engineering
CN108680433A (en) * 2018-05-15 2018-10-19 北京大学 A kind of method and apparatus measuring artery outer diameter variation
RU2693819C1 (en) * 2018-05-25 2019-07-04 федеральное государственное бюджетное образовательное учреждение высшего образования "Новгородский государственный университет имени Ярослава Мудрого" Method and device for determining ischemic brain condition
CN209102521U (en) * 2018-07-29 2019-07-12 郑州大学 A kind of easy small-caliber tissue engineered blood vessels bracket biomechanical property test device
CN211264769U (en) * 2019-12-13 2020-08-14 中国科学院深圳先进技术研究院 Vascular compliance simulation device

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009233226A (en) * 2008-03-28 2009-10-15 Yotaro Hatamura Blood vessel shape measuring instrument and vascular compliance measuring method
CN101393095A (en) * 2008-10-16 2009-03-25 东华大学 Artificial blood vessel compliance emulation test device and test method thereof
CN102680324A (en) * 2012-06-01 2012-09-19 苏州大学 Biomechanical property testing method for blood vessel prosthesis and device thereof
CN202814798U (en) * 2012-06-01 2013-03-20 苏州大学 Biomechanical property testing device for artificial blood vessels
CN106604678A (en) * 2014-08-22 2017-04-26 心血管系统股份有限公司 Methods, devices and systems for sensing, measuring and/or characterizing vessel and/or lesion compliance and/or elastance changes during vascular procedures
CN206161438U (en) * 2016-11-02 2017-05-10 郑州大学 Blood vessel organizational project support mechanical properties test system
CN107748128A (en) * 2017-11-27 2018-03-02 郑州大学 The biomechanical property test device and method of a kind of scaffold for vascular tissue engineering
CN108680433A (en) * 2018-05-15 2018-10-19 北京大学 A kind of method and apparatus measuring artery outer diameter variation
RU2693819C1 (en) * 2018-05-25 2019-07-04 федеральное государственное бюджетное образовательное учреждение высшего образования "Новгородский государственный университет имени Ярослава Мудрого" Method and device for determining ischemic brain condition
CN209102521U (en) * 2018-07-29 2019-07-12 郑州大学 A kind of easy small-caliber tissue engineered blood vessels bracket biomechanical property test device
CN211264769U (en) * 2019-12-13 2020-08-14 中国科学院深圳先进技术研究院 Vascular compliance simulation device

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