CN114002075A - Artificial blood vessel compliance testing device - Google Patents

Artificial blood vessel compliance testing device Download PDF

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Publication number
CN114002075A
CN114002075A CN202111275539.4A CN202111275539A CN114002075A CN 114002075 A CN114002075 A CN 114002075A CN 202111275539 A CN202111275539 A CN 202111275539A CN 114002075 A CN114002075 A CN 114002075A
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blood vessel
artificial blood
adjusting
support
testing device
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CN202111275539.4A
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CN114002075B (en
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赵荟菁
伊光辉
孟凯
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Suzhou University
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Suzhou University
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N3/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N3/08Investigating strength properties of solid materials by application of mechanical stress by applying steady tensile or compressive forces
    • G01N3/10Investigating strength properties of solid materials by application of mechanical stress by applying steady tensile or compressive forces generated by pneumatic or hydraulic pressure
    • G01N3/12Pressure testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N3/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N3/02Details
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N3/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N3/02Details
    • G01N3/06Special adaptations of indicating or recording means
    • G01N3/068Special adaptations of indicating or recording means with optical indicating or recording means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0001Type of application of the stress
    • G01N2203/0003Steady
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0014Type of force applied
    • G01N2203/0016Tensile or compressive
    • G01N2203/0019Compressive
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/003Generation of the force
    • G01N2203/0042Pneumatic or hydraulic means
    • G01N2203/0048Hydraulic means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/02Details not specific for a particular testing method
    • G01N2203/025Geometry of the test
    • G01N2203/0258Non axial, i.e. the forces not being applied along an axis of symmetry of the specimen
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/02Details not specific for a particular testing method
    • G01N2203/026Specifications of the specimen
    • G01N2203/0262Shape of the specimen
    • G01N2203/0274Tubular or ring-shaped specimens
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/02Details not specific for a particular testing method
    • G01N2203/06Indicating or recording means; Sensing means
    • G01N2203/0641Indicating or recording means; Sensing means using optical, X-ray, ultraviolet, infrared or similar detectors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/02Details not specific for a particular testing method
    • G01N2203/06Indicating or recording means; Sensing means
    • G01N2203/067Parameter measured for estimating the property
    • G01N2203/0676Force, weight, load, energy, speed or acceleration
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/02Details not specific for a particular testing method
    • G01N2203/06Indicating or recording means; Sensing means
    • G01N2203/067Parameter measured for estimating the property
    • G01N2203/0682Spatial dimension, e.g. length, area, angle

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Prostheses (AREA)

Abstract

The embodiment of the invention provides an artificial blood vessel compliance testing device, which comprises a fixing device, a circulating water assembly and a signal processing assembly, wherein the fixing device comprises a fixing seat, a front support and a rear support, the fixing seat comprises a bottom plate and a plurality of pairs of side plates, the artificial blood vessel is fixed between the front support and the rear support, a flow winding roller is optionally arranged on the bottom plate, so that the artificial blood vessel can optionally pass through the flow winding roller or not, and the circulating water assembly is used for conveying circulating water to the artificial blood vessel; and the signal processing assembly is configured to obtain the compliance data of the artificial blood vessel according to the pressure information and the radial displacement information, and meets the compliance test requirements of the artificial blood vessel under linear or different curvature requirements by optionally arranging a streaming roller on the bottom plate.

Description

Artificial blood vessel compliance testing device
Technical Field
The application relates to a flexible material testing instrument, in particular to an artificial blood vessel compliance testing device.
Background
The human artery has viscoelastic property and plays an important role in the function of the cardiovascular system, when the heart contracts, the blood vessel is full, the vessel wall expands, and the expansibility plays an important role in stabilizing blood. The compliance of the artificial blood vessel refers to the deformation responsiveness of the artificial blood vessel to the stress inside the duct, and plays an important role in graft complications, especially at anastomoses. As the implantation time is increased and the implanted blood vessel grows along with fibrous tissues, the compliance is reduced to 1/3 of the original value, the probability of thrombus appearing in the inner cavity is increased due to the loss of the compliance, the new inner cavity is thickened, arteriosclerosis is formed at the tail end of the blood vessel, and therefore, the measurement and the matching of the compliance are an important problem in the biomechanical performance of the artificial blood vessel.
In the prior art, for example, YY-0500-2004/ISO 7198; the simple device shown in the 1998 standard is used for detection, but in practice, when the artificial blood vessel is sometimes required to take a curved shape or the like, detection is difficult by the existing device.
Disclosure of Invention
In view of the above-mentioned shortcomings of the prior art, the present application provides an artificial blood vessel compliance testing device to solve the above-mentioned technical problems.
An artificial blood vessel compliance testing device comprises a fixing device, a circulating water assembly and a signal processing assembly:
the fixing device comprises a fixing seat, a front support and a rear support, wherein the fixing seat comprises a bottom plate and a plurality of pairs of side plates, the bottom plate is provided with an accommodating space in a surrounding mode, the side plates are oppositely arranged on the periphery of the bottom plate, the front support and the rear support are respectively arranged on the pair of side plates, the artificial blood vessel is fixed between the front support and the rear support and passes through the accommodating space, and a flow-winding roller is optionally arranged on the bottom plate so that the artificial blood vessel can selectively pass through the flow-winding roller or not;
the circulating water assembly is used for conveying circulating water to the artificial blood vessel;
the signal processing assembly comprises pressure sensors, a laser displacement sensor and a signal processing assembly, wherein the pressure sensors are arranged on the front support and the rear support and used for acquiring pressure information, the laser displacement sensor is arranged on the fixing device and used for acquiring artificial blood vessel radial displacement information, the signal processing assembly is connected with the pressure sensors and the laser displacement sensor, and the signal processing assembly is configured to obtain artificial blood vessel compliance data according to the pressure information and the radial displacement information.
Furthermore, the bottom plate on be provided with a plurality of connecting holes, the streaming roller include roll body and link, wherein, the link be configured into can insert establish in the connecting hole, the signal processing subassembly include the mount pad, laser displacement sensor set up on the mount pad, the mount pad include the installation end, the installation end fix in the connecting hole.
Furthermore, a pair of the side plates comprises a first side plate and a second side plate, the front support is arranged on the first side plate, the rear support is arranged on the second side plate, the fixing seat is further provided with an adjusting device, the adjusting device comprises a first adjusting piece and a second adjusting piece, the first adjusting piece is configured to adjust the position of the front support in the vertical direction, and the second adjusting piece is configured to adjust the position of the rear support in the horizontal direction.
Furthermore, a first adjusting groove is formed in the first side plate, the front support is arranged in the first adjusting groove, and the first adjusting piece movably limits the position of the front support in the height direction of the first adjusting groove.
Furthermore, the second side plate is provided with a third adjusting hole, the rear support is arranged in the third adjusting hole, and the second adjusting piece can movably limit the position of the rear support in the horizontal direction of the third adjusting hole.
Further, still be provided with the fourth adjustment tank in the top of third regulation hole, the length of fourth adjustment tank equals with the length of third regulation hole, and, the fourth adjustment tank extends to the third regulation hole from the top surface of second curb plate, the second regulating part include that one end stretches out the top surface, the other end is connected with the back support and the montant of holding in the fourth adjustment tank, the montant stretch out the one end of top surface and be provided with the screw thread to there is the nut through threaded connection.
Furthermore, the bottom plate is in a regular polygon shape with even number of sides, and the number of pairs of the side plates is 1/2 of the number of sides of the bottom plate.
Furthermore, the mounting seat comprises a pair of supporting plates arranged at intervals, the artificial blood vessel penetrates between the pair of supporting plates arranged at intervals, the laser displacement sensor comprises a transmitting end and a receiving end, the transmitting end is used for transmitting light beams, the receiving end is used for receiving the light beams, the transmitting end and the receiving end are respectively arranged on the pair of supporting plates, and the artificial blood vessel vertically passes through a light beam plane transmitted by the transmitting end of the laser displacement sensor.
Furthermore, at least one part of the contour line of the projection of the at least one streaming roller on the bottom plate is an involute.
Has the advantages that: the embodiment of the invention provides an artificial blood vessel compliance testing device, which comprises a fixing device, a circulating water assembly and a signal processing assembly, wherein the fixing device comprises a fixing seat, a front support and a rear support, the fixing seat comprises a bottom plate and a plurality of pairs of side plates, the artificial blood vessel is fixed between the front support and the rear support, a flow winding roller is optionally arranged on the bottom plate, so that the artificial blood vessel can optionally pass through the flow winding roller or not, and the circulating water assembly is used for conveying circulating water to the artificial blood vessel; and the signal processing assembly is configured to obtain the compliance data of the artificial blood vessel according to the pressure information and the radial displacement information, and meets the compliance test requirements of the artificial blood vessel under linear or different curvature requirements by optionally arranging a streaming roller on the bottom plate.
Drawings
FIG. 1 is a schematic diagram of an apparatus for testing compliance of an artificial blood vessel according to the present invention;
FIG. 2 is a schematic view of the fixing device shown in FIG. 1;
FIG. 3 is a schematic view of an artificial blood vessel passing around a flow-around roller;
FIG. 4 is a schematic view of the projection profile of the streaming roller onto the base plate in another embodiment.
Illustration of the symbols:
a fixing device 10; an accommodating space 100; a base plate 101; a side plate 102; a first regulation groove 103; a second regulating groove 104; a third regulation hole 105; a fourth regulation groove 106; a front support 11; a front three-way valve 111; a pre-pressure tube 112; a front connector 113; a rear support 12; a rear three-way valve 111; a connecting tube 112; a rear connector 113; a mounting base 13; a connecting hole 15; the streaming rollers 151, 251; a second adjusting member 142; a peristaltic pump 20; a circulating water tank 30; a signal processing unit 50; a computer 60; a pressure sensor 71; a laser displacement sensor 72; an artificial blood vessel 80.
Detailed Description
The present application will be described in further detail with reference to examples. It is to be noted that the following examples are only illustrative of the present application, and do not limit the scope of the present application. Likewise, the following examples are only some examples and not all examples of the present application, and all other examples obtained by a person of ordinary skill in the art without any inventive step are within the scope of the present application.
In the description of the present application, it is noted that the terms "first", "second", and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implying any number of technical features indicated. Thus, a feature defined as "first," "second," etc. may explicitly or implicitly include one or more of that feature.
Referring to fig. 1-3, an embodiment of the invention provides a compliance testing device for an artificial blood vessel 80, which includes a fixing device 10, a circulating water assembly and a signal processing assembly.
The fixing device 10 is used for fixing the artificial blood vessel 80, and comprises a fixing seat, a front support 11 and a rear support 12, wherein the front support 11 and the rear support 12 are arranged on the fixing seat, and the artificial blood vessel 80 is fixed between the front support 11 and the rear support 12.
The fixing base include bottom plate 101 and set up a plurality of pairs of curb plates 102 at bottom plate 101 periphery, bottom plate 101 and curb plate 102 enclose and establish into an open accommodation space 100, it is a pair of curb plate 102 on be provided with preceding support 11 and back support 12 respectively, wherein, preceding support 11 including preceding three-way valve 111, pre-compaction pipe 112 and preceding connector 113 that set gradually, back support 12 including the back three-way valve 111, connecting pipe 112 and the back connector 113 that set gradually, preceding connector 113, back connector 113 be used for connecting the both ends of artificial blood vessel 80 respectively, artificial blood vessel 80 pass accommodation space 100.
Preferably, the side plates 102 disposed on the periphery of the bottom plate 101 are sequentially connected, so that each side plate 102 forms a complete ring shape.
In one embodiment, the pair of side plates 102 includes a first side plate and a second side plate, the front seat 11 is disposed on the first side plate, and the rear seat 12 is disposed on the second side plate.
Preferably, the bottom plate 101 has a regular polygon shape with even number of sides, so that 1/2 pairs of side plates 102 are arranged along the periphery of the bottom plate 101, and a corresponding number of front supporting seats 11 and rear supporting seats 12 are arranged on the side plates 102, thereby conveniently testing the artificial blood vessels 80 with different tube diameters.
Preferably, the bottom plate 101 is a regular hexagon, and is provided with three groups of front supports 11 and rear supports 12 for fitting artificial blood vessels 80 of 4mm, 5mm and 6 mm.
The base plate 101 may further optionally be provided with a flow winding roller 151, so that the artificial blood vessel 80 may optionally pass through the flow winding roller 151 or not pass through the flow winding roller 151, specifically, in this embodiment, the base plate 101 is provided with a plurality of connection holes 15, the flow winding roller 151 includes a roller body and a connection end, wherein the connection end is configured to be inserted into the connection hole 15, it can be understood that a projection of a connecting line between the front connection head 113 and the rear connection head 113 on the base plate 101 intersects a projection of at least one flow winding roller 151 on the base plate 101, in this case, when the artificial blood vessel 80 is provided between the front connection head 113 and the rear connection head 113, at least one flow winding roller 151 is bound to block the artificial blood vessel 80, so that the artificial blood vessel 80 needs to bypass the flow winding roller 151, so that the artificial blood vessel 80 is bent at the flow winding roller 151, and at the same time, when the flow winding rollers 151 are not inserted into all the connection holes 15 or at least when the flow winding rollers 151 are not inserted into the path connecting the front connection head 113 and the rear connection head 113, the artificial blood vessel 80 is linear and does not form a curve.
It will be understood that when the plurality of connection holes 15 provided on the base plate 101 are arranged in a predetermined pattern, the artificial blood vessel 80 provided between the front connection head 113 and the rear connection head 113 is bent in a predetermined pattern.
It will be appreciated that when the wrap rollers 151 are arranged to have different diameters, the prosthesis 80 will form a curved configuration with different curvatures.
Preferably, the connection holes 15 are formed in an array on the bottom plate 101.
Referring also to fig. 4, in a preferred embodiment, at least a portion of the projected contour of the flow-around roller 251 on the base plate 101 is an involute curve, in which case, different curvature requirements of the vascular prosthesis 80 can be satisfied by one flow-around roller 151.
Further, the fixing base is further provided with an adjusting device for adjusting the shape of the artificial blood vessel 80 in the accommodating space 100, specifically, the adjusting device includes a first adjusting part and a second adjusting part 142, wherein the first adjusting part is configured to adjust the position of the front support 11 in the vertical direction, the second adjusting part 142 is configured to adjust the position of the rear support 12 in the horizontal direction, of course, in other embodiments, the first adjusting part may also be provided to adjust the position of the front support 11 in the horizontal direction or simultaneously adjust the positions in the vertical and horizontal directions, and the second adjusting part 142 adjusts the position of the rear support 12 in the vertical direction or simultaneously adjust the positions in the horizontal and vertical directions, it can be understood that when the position of the front support 11 in the vertical direction is changed, the position of the front end of the artificial blood vessel 80 connected between the front support 11 and the rear support 12 in the vertical direction is changed, the shape of the artificial blood vessel 80 in the accommodating space 100 is changed, and particularly, when the artificial blood vessel 80 is wound around the wind roller 151, the shape of the artificial blood vessel 80 in the accommodating space 100 is also changed when the position of the rear holder 12 in the horizontal direction is changed.
Specifically, in this embodiment, the first side plate 102 is provided with a first adjusting groove 103, the front support 11 is disposed in the first adjusting groove 103, and the first adjusting member movably defines a position of the front support 11 in a height direction of the first adjusting groove 103, so as to adjust a position of the front support 11 in a vertical direction.
In one embodiment, the first adjusting member is a bolt, the bolt is inserted into a vertically threaded hole, and the front end of the bolt is connected to the front support 11, and when the bolt is rotated, the front end of the bolt moves in the vertical direction to move the front support 11 in the vertical direction.
In this embodiment, a second adjusting groove 104 is further disposed below the first adjusting groove 103, the length direction of the second adjusting groove 104 is parallel to the vertical direction and has an opening facing outward, the first adjusting member includes a vertical supporting member accommodated in the second adjusting groove 104 and a horizontal supporting member perpendicular to the vertical supporting member and having one end extending out of the opening of the second adjusting groove 104 along the horizontal direction and the other end connected to the vertical supporting member, one end of the horizontal supporting member extending out of the second adjusting groove 104 is provided with a screw thread and a nut screwed onto the horizontal supporting member, when the height of the front support 11 in the vertical direction needs to be adjusted, the nut is loosened, the horizontal supporting member moves along the length direction of the second adjusting groove 104 through the external force, so that the front support 11 moves along the vertical direction and is adjusted to a predetermined position, the nut is screwed, so that the position of the horizontal support is fixed and thus the position of the front mount 11 is fixed.
Preferably, the first adjusting groove 103 is an open groove, and the opening direction of the first adjusting groove 103 faces the vertical direction.
The second side plate 102 is provided with a third adjusting hole 105, the rear support 12 is disposed in the third adjusting hole 105, and the second adjusting element 142 movably limits the position of the rear support 12 in the horizontal direction of the third adjusting hole 105, so as to adjust the position of the rear support 12 in the horizontal direction.
It is understood that the third adjusting hole 105 includes a length direction, the length direction of the third adjusting hole 105 is parallel to the horizontal direction, and the third adjusting hole 105 penetrates through the thickness direction of the second side plate 102.
In this embodiment, a fourth adjusting groove 106 is further disposed above the third adjusting hole 105, the length of the fourth adjusting groove 106 is equal to the length of the third adjusting hole 105, the fourth adjusting groove 106 extends from the top surface of the second side plate 102 to the third adjusting hole 105, the second adjusting member 142 includes a vertical rod, one end of the vertical rod extends out of the top surface, the other end of the vertical rod is connected with the rear support 12 and is accommodated in the fourth adjusting groove 106, the end of the vertical rod extending out of the top surface is provided with a thread and is connected with a nut through the thread, when the position of the rear support 12 in the horizontal direction needs to be adjusted, the nut is loosened, the vertical rod moves along the length direction of the fourth adjusting groove 106 through external force, so that the rear support 12 moves along the horizontal direction and is adjusted to a predetermined position, the nut is screwed, the position of the vertical rod is fixed, and the position of the rear support 12 is fixed.
The circulating water assembly is used for conveying circulating water to the artificial blood vessel 80, and specifically, the circulating water assembly comprises a circulating water tank 30, a peristaltic pump 20 and a connecting pipe 112, and as can be understood, the circulating water assembly is connected with a front three-way valve 111 and a rear three-way valve 111 through pipes.
The signal processing assembly comprises a pressure sensor 71 arranged on the three-way valve, a laser displacement sensor 72 arranged on the fixing assembly and a signal processing unit 50 connected with the pressure sensor 71 and the laser displacement sensor 72, wherein the pressure sensor 71 is used for acquiring pressure information, the laser displacement sensor 72 is used for detecting the radial displacement information of the artificial blood vessel 80, and the signal processing unit 50 acquires the pressure information and the radial displacement information and obtains the compliance data of the artificial blood vessel 80.
Further, the bottom plate 101 is further provided with an installation seat 13, the laser displacement sensor 72 is arranged on the installation seat 13, in this embodiment, the installation seat 13 includes a pair of support plates arranged at intervals, the artificial blood vessel 80 is arranged between the pair of support plates arranged at intervals in a penetrating manner, and the laser displacement sensor 72 includes a transmitting end and a receiving end, wherein the transmitting end and the receiving end are respectively arranged on the pair of support plates.
Further, the mounting seat 13 includes a mounting end, and the mounting end is fixed in the connecting hole 15.
That is, in this case, the connection holes 15 can be used to fix the streaming roller 151 and the mounting seat 13 at the same time, thereby conveniently adjusting the positions of the streaming roller 151 and the mounting seat 13.
The present invention will be further described with reference to a method for testing the compliance of the artificial blood vessel 80 using the device for testing the compliance of the artificial blood vessel 80.
The specific test steps for testing the compliance of the artificial blood vessel 80 by using the test device are as follows:
s1: selecting the caliber and shape of the artificial blood vessel 80 to be tested;
an appropriate connection port is selected according to the diameter of the artificial blood vessel 80 to be tested, and whether or not the orbiting roller 151 is used is determined according to the shape to be tested, and if the straight shape is tested, the orbiting roller 151 does not need to be attached, and if the curved shape is tested, the position of the orbiting roller is determined as necessary.
S2: the circulating water component is connected, the pressure sensor 71 is connected, the laser displacement sensor 72 is placed, and the signal processing component is connected;
in this embodiment, the pipes connect the peristaltic pump 20, the circulating water tank 30, the front three-way valve 111, and the rear three-way valve 111, and the liquid in the circulating water tank 30 should not exceed 2/3 of the volume thereof.
The pressure sensor 71 is screwed to the three-way valve to ensure tight connection and prevent water leakage.
The laser displacement sensor 72 is disposed at a predetermined position, and the artificial blood vessel 80 passes between the transmitting end and the receiving end of the laser displacement sensor 72, it can be understood that the position of the laser displacement sensor 72 is adjusted as required, so that the artificial blood vessel 80 perpendicularly passes through the light beam plane emitted by the transmitting end of the laser displacement sensor 72.
The pressure sensor 71 and the laser displacement sensor 72 are connected to the signal processing unit 50, and preferably, the signal processing unit 50 can be connected to a computer 60 to further process the signals.
S3: circulating water is conveyed to the artificial blood vessel 80 through the circulating water assembly, pressure information is obtained through the pressure sensor 71, radial displacement information of the artificial blood vessel 80 is obtained through the laser displacement sensor 72, and the circulating water pressure range is adjusted to meet YY-0500-; 1998, the test is carried out at three different high and low pressures, respectively, wherein the low pressure is 50-90mmHg, the medium pressure is 80-120mmHg, and the high pressure is 110-150 mmHg.
S4: obtaining the compliance data of the artificial blood vessel 80 according to the pressure information and the radial displacement information;
after the pressure adjustment is stable, obtaining the compliance data of the artificial blood vessel 80 according to the pressure information and the radial displacement information of the artificial blood vessel 80, and specifically calculating according to the following steps:
a) if the outer diameter is measured directly, the inner radius is calculated from the equation
Wherein Rp ═ (Dp/2) -t
Rp-inner radius after pressurization;
dp-outside diameter after pressurization;
t-vessel wall thickness;
note that for biological materials, the wall thickness can vary significantly at different pressures, and if the vessel wall is incompressible, the same value can be used for the vessel wall thickness at any pressure.
b) If the volume and length are measured directly, the radius after pressurization must be calculated from the volume and length;
c) once the inner radius of the prosthesis is calculated at a set of pressures, the radial compliance can be obtained by:
compliance (%) - (R)P1-RP2)/RP1(P1-P2)]×104
In the formula:
P1low pressure values in millimeters of mercury (mmHg)
P2High pressure value in millimeters of mercury (mmHg)
The radial compliance calculated above is expressed as a percentage change per 100mmHg diameter.
The above description is only an example of the present application and is not intended to limit the scope of the present application, and all modifications of equivalent structures and equivalent processes, which are made by the contents of the specification and the drawings, or which are directly or indirectly applied to other related technical fields, are intended to be included within the scope of the present application.

Claims (9)

1. An artificial blood vessel compliance testing device, which comprises a fixing device, a circulating water component and a signal processing component, and is characterized in that,
the fixing device comprises a fixing seat, a front support and a rear support, wherein the fixing seat comprises a bottom plate and a plurality of pairs of side plates, the bottom plate is provided with an accommodating space in a surrounding mode, the side plates are oppositely arranged on the periphery of the bottom plate, the front support and the rear support are respectively arranged on the pair of side plates, the artificial blood vessel is fixed between the front support and the rear support and passes through the accommodating space, and a flow-winding roller is optionally arranged on the bottom plate so that the artificial blood vessel can selectively pass through the flow-winding roller or not;
the circulating water assembly is used for conveying circulating water to the artificial blood vessel;
the signal processing assembly comprises pressure sensors, a laser displacement sensor and a signal processing assembly, wherein the pressure sensors are arranged on the front support and the rear support and used for acquiring pressure information, the laser displacement sensor is arranged on the fixing device and used for acquiring artificial blood vessel radial displacement information, the signal processing assembly is connected with the pressure sensors and the laser displacement sensor, and the signal processing assembly is configured to obtain artificial blood vessel compliance data according to the pressure information and the radial displacement information.
2. The artificial blood vessel testing device of claim 1, wherein the base plate has a plurality of connection holes, the orbiting roller comprises a roller body and a connection end, wherein the connection end is configured to be inserted into the connection hole, the signal processing assembly comprises a mounting seat, the laser displacement sensor is disposed on the mounting seat, the mounting seat comprises a mounting end, and the mounting end is fixed in the connection hole.
3. The vascular prosthesis testing device according to claim 2, wherein the pair of side plates comprises a first side plate and a second side plate, the front support is disposed on the first side plate, the rear support is disposed on the second side plate, and the fixing base is further provided with an adjusting device, the adjusting device comprises a first adjusting member and a second adjusting member, wherein the first adjusting member is configured to adjust the position of the front support in the vertical direction, and the second adjusting member is configured to adjust the position of the rear support in the horizontal direction.
4. The vascular prosthesis testing device according to claim 3, wherein the first side plate has a first adjustment groove formed therein, the front support is disposed in the first adjustment groove, and the first adjustment member movably defines a position of the front support in a height direction of the first adjustment groove.
5. The vascular prosthesis testing device of claim 3, wherein the second side plate is provided with a third adjustment hole, the rear support is disposed in the third adjustment hole, and the second adjustment member movably defines a position of the rear support in a horizontal direction of the third adjustment hole.
6. The artificial blood vessel testing device of claim 5, wherein a fourth adjusting groove is further provided above the third adjusting hole, the length of the fourth adjusting groove is equal to the length of the third adjusting hole, the fourth adjusting groove extends from the top surface of the second side plate to the third adjusting hole, the second adjusting member comprises a vertical rod, one end of the vertical rod extends out of the top surface, the other end of the vertical rod is connected with the rear support and is accommodated in the fourth adjusting groove, and the end of the vertical rod, which extends out of the top surface, is provided with a screw thread and is connected with a nut through the screw thread.
7. The artificial blood vessel testing device of claim 1, wherein the bottom plate has a regular polygonal shape with an even number of sides, and the number of pairs of the side plates is 1/2 of the number of sides of the bottom plate.
8. The artificial blood vessel testing device of claim 2, wherein the mounting seat comprises a pair of spaced apart support plates, the artificial blood vessel is inserted between the pair of spaced apart support plates, the laser displacement sensor comprises a transmitting end for transmitting a light beam and a receiving end for receiving the light beam, wherein the transmitting end and the receiving end are respectively disposed on the pair of support plates, and the artificial blood vessel passes through a plane of the light beam emitted from the transmitting end of the laser displacement sensor perpendicularly.
9. An artificial blood vessel testing device according to any of claims 1-8 wherein at least a portion of the contour of the projection of at least one of the streaming rollers onto the base plate is an involute curve.
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Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101393095A (en) * 2008-10-16 2009-03-25 东华大学 Artificial blood vessel compliance emulation test device and test method thereof
JP2009233226A (en) * 2008-03-28 2009-10-15 Yotaro Hatamura Blood vessel shape measuring instrument and vascular compliance measuring method
CN102680324A (en) * 2012-06-01 2012-09-19 苏州大学 Biomechanical property testing method for blood vessel prosthesis and device thereof
CN202814798U (en) * 2012-06-01 2013-03-20 苏州大学 Biomechanical property testing device for artificial blood vessels
CN106604678A (en) * 2014-08-22 2017-04-26 心血管系统股份有限公司 Methods, devices and systems for sensing, measuring and/or characterizing vessel and/or lesion compliance and/or elastance changes during vascular procedures
CN206161438U (en) * 2016-11-02 2017-05-10 郑州大学 Blood vessel organizational project support mechanical properties test system
CN107748128A (en) * 2017-11-27 2018-03-02 郑州大学 The biomechanical property test device and method of a kind of scaffold for vascular tissue engineering
CN108680433A (en) * 2018-05-15 2018-10-19 北京大学 A kind of method and apparatus measuring artery outer diameter variation
RU2693819C1 (en) * 2018-05-25 2019-07-04 федеральное государственное бюджетное образовательное учреждение высшего образования "Новгородский государственный университет имени Ярослава Мудрого" Method and device for determining ischemic brain condition
CN209102521U (en) * 2018-07-29 2019-07-12 郑州大学 A kind of easy small-caliber tissue engineered blood vessels bracket biomechanical property test device
CN211264769U (en) * 2019-12-13 2020-08-14 中国科学院深圳先进技术研究院 Vascular compliance simulation device

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009233226A (en) * 2008-03-28 2009-10-15 Yotaro Hatamura Blood vessel shape measuring instrument and vascular compliance measuring method
CN101393095A (en) * 2008-10-16 2009-03-25 东华大学 Artificial blood vessel compliance emulation test device and test method thereof
CN102680324A (en) * 2012-06-01 2012-09-19 苏州大学 Biomechanical property testing method for blood vessel prosthesis and device thereof
CN202814798U (en) * 2012-06-01 2013-03-20 苏州大学 Biomechanical property testing device for artificial blood vessels
CN106604678A (en) * 2014-08-22 2017-04-26 心血管系统股份有限公司 Methods, devices and systems for sensing, measuring and/or characterizing vessel and/or lesion compliance and/or elastance changes during vascular procedures
CN206161438U (en) * 2016-11-02 2017-05-10 郑州大学 Blood vessel organizational project support mechanical properties test system
CN107748128A (en) * 2017-11-27 2018-03-02 郑州大学 The biomechanical property test device and method of a kind of scaffold for vascular tissue engineering
CN108680433A (en) * 2018-05-15 2018-10-19 北京大学 A kind of method and apparatus measuring artery outer diameter variation
RU2693819C1 (en) * 2018-05-25 2019-07-04 федеральное государственное бюджетное образовательное учреждение высшего образования "Новгородский государственный университет имени Ярослава Мудрого" Method and device for determining ischemic brain condition
CN209102521U (en) * 2018-07-29 2019-07-12 郑州大学 A kind of easy small-caliber tissue engineered blood vessels bracket biomechanical property test device
CN211264769U (en) * 2019-12-13 2020-08-14 中国科学院深圳先进技术研究院 Vascular compliance simulation device

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