CN113995709A - Shampoo containing plant composite anti-shedding agent and preparation method thereof - Google Patents

Shampoo containing plant composite anti-shedding agent and preparation method thereof Download PDF

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Publication number
CN113995709A
CN113995709A CN202111515163.XA CN202111515163A CN113995709A CN 113995709 A CN113995709 A CN 113995709A CN 202111515163 A CN202111515163 A CN 202111515163A CN 113995709 A CN113995709 A CN 113995709A
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extract
composite anti
plant composite
plant
shampoo
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胡志发
莫方东
罗颖
黄余赢
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Guangzhou Fage Fine Chemical Co ltd
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Guangzhou Fage Fine Chemical Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/442Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/737Galactomannans, e.g. guar; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/12Preparations containing hair conditioners
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/42Colour properties
    • A61K2800/43Pigments; Dyes
    • A61K2800/436Interference pigments, e.g. Iridescent, Pearlescent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/48Thickener, Thickening system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/596Mixtures of surface active compounds

Abstract

The invention relates to a shampoo containing a plant composite anti-release agent and a preparation method thereof, and the shampoo comprises the plant composite anti-release agent, sodium laureth sulfate, cocamidopropyl betaine, octyl/decyl glucoside, ethylene glycol distearate, polydimethylsiloxane, guar gum hydroxypropyl trimethyl ammonium chloride, cocamide MEA, acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, methyl hydroxybenzoate, phenoxyethanol, chlorphenesin, essence and the balance of deionized water; the plant composite anti-hair loss agent is applied to shampoo, has high-efficiency anti-hair loss effect under the synergistic action of various plant extracts, is safer and more environment-friendly compared with a chemical anti-hair loss pilatory, and has milder effect on scalp; in addition, the shampoo prepared by the method can keep the effective components of the components on the scalp, so that the effective components cannot be damaged in the processing process, and the obtained product has stable performance and is suitable for large-scale production.

Description

Shampoo containing plant composite anti-shedding agent and preparation method thereof
Technical Field
The invention relates to the technical field of hair care products, in particular to shampoo containing a plant composite anti-shedding agent and a preparation method thereof.
Background
With the acceleration of the life rhythm of people, the working pressure is increased, the work and rest time is relatively disordered, and the hair loss phenomenon is serious due to the factors of irregular life diet and the like.
At present, although products for preventing alopecia, growing hair and nourishing hair are sold in the market, the alopecia prevention effect is not obvious, and most of the products for preventing alopecia have certain irritation to the scalp and are not beneficial to scalp health.
Disclosure of Invention
Therefore, in order to solve the problems in the prior art, a shampoo containing a plant composite anti-release agent and a preparation method thereof are needed.
A shampoo containing a plant composite anti-release agent comprises, by weight, 1% -10% of the plant composite anti-release agent, 15% -25% of sodium laureth sulfate, 1% -10% of cocamidopropyl betaine, 1% -5% of octyl/decyl glucoside, 1% -3% of ethylene glycol distearate, 1% -5% of polydimethylsiloxane, 0.1% -0.5% of guar hydroxypropyltrimonium chloride, 1.0% -2.0% of cocamide MEA, 0.1% -0.5% of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.1% -0.5% of methyl hydroxybenzoate, 0.1% -1.0% of phenoxyethanol, 0.1% -0.5% of chlorphenesin, 0.1% -0.5% of essence and the balance of deionized water,
the plant composite anti-dropping agent comprises 20-50% of coffee extract, 20-35% of ginseng extract, 10-30% of ginger root extract and 1-10% of lavender extract.
In one embodiment, the plant composite anti-dropping agent comprises 30% -40% of coffee extract, 20% -30% of ginseng extract, 15% -20% of ginger root extract and 5% -10% of lavender extract.
In one embodiment, the weight ratio of the caffeine extract, the ginseng extract, the ginger root extract and the lavender extract is 50:30:10: 10.
In one embodiment, the preparation method of the plant composite anti-shedding agent comprises the following steps:
s1: weighing the coffee extract, the ginseng extract, the ginger root extract and the lavender extract according to the weight ratio;
s2: adding 10 times of 70% ethanol into the weighed raw material components, decocting and refluxing for 3 times, each time for 1h, filtering, and combining the 3 times of filtrates;
s3: putting the filtrate obtained in the step S2 into a freezing centrifuge for centrifugation, and taking supernatant, wherein the rotating speed of the freezing centrifuge is 5000 rpm/min;
s4: recovering ethanol from the supernatant, making the obtained supernatant into fluid extract, and diluting with water to obtain plant composite anticreep agent with concentration of 1g/L for use.
In one embodiment, the addition amount of the plant composite anti-release agent in the shampoo is 5% -8%.
In one embodiment, the shampoo containing the plant complex release preventing agent comprises 8% of the plant complex release preventing agent, 16% of sodium laureth sulfate, 7% of cocamidopropyl betaine, 2% of octyl/decyl glucoside, 1% of ethylene glycol distearate, 3% of polydimethylsiloxane, 0.3% of guar hydroxypropyltrimonium chloride, 1.8% of cocamide MEA, 0.2% of acrylic acid/C10-30 alkanol acrylate cross-linked polymer, 0.2% of methyl hydroxybenzoate, 0.6% of phenoxyethanol, 0.2% of chlorphenesin, 0.5% of essence and the balance of deionized water.
A preparation method of shampoo containing plant compound anti-shedding agent comprises the following steps:
s1: adding a proper amount of deionized water into a container, heating to 45-55 ℃ in a water bath, dispersing the acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer in water in advance, adding the mixture into the container, heating to 80-85 ℃, and stirring at constant temperature until the acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer is completely dissolved;
s2: adding the sodium laureth sulfate, the cocamide MEA and the methylparaben, keeping the temperature between 80 and 85 ℃, and stirring until the sodium laureth sulfate, the cocamide MEA and the methylparaben are completely dissolved;
s3: pre-dispersing the guar gum hydroxypropyl trimethyl ammonium chloride with water, adding the guar gum hydroxypropyl trimethyl ammonium chloride into a container, and stirring until the guar gum hydroxypropyl trimethyl ammonium chloride is completely dissolved;
s4: cooling to 55-60 ℃, adding the cocamidopropyl betaine and the octyl/decyl glucoside, and stirring until complete dissolution;
s5: cooling to 45 ℃, adding the polydimethylsiloxane, and rapidly stirring until the mixture is completely uniform;
s6: adding the ethylene glycol distearate, the phenoxyethanol, the chlorphenesin, the essence, the plant composite anti-shedding agent and the balance of deionized water, thoroughly and uniformly stirring, adjusting the pH, and standing.
In one embodiment, the pH is 5.6-6.5.
According to the shampoo containing the plant composite anti-release agent, the sodium laureth sulfate, the cocamidopropyl betaine and the octyl/decyl glucoside are used as surfactants, so that the shampoo has good cleaning, foaming and conditioning effects, is low in irritation and mild in performance, and is beneficial to enhancing the flexibility of the scalp; the ethylene glycol distearate is used as a pearling agent and has the functions of nourishing and protecting hair; the polydimethylsiloxane and the guar gum hydroxypropyl trimethyl ammonium chloride are used as conditioning agents, so that the hair damaged by chemical or physical action can be repaired, the hair quality is improved, and the hair becomes thick and flexible; the cocamide MEA and the acrylic acid/C10-30 alkanol acrylate cross-linked polymer are used as thickening agents, so that irritation can be effectively reduced, and hair and scalp can be better protected.
Further, in the plant composite anti-shedding agent, the caffeine extract has the effect of hair follicle proliferation, can penetrate through hair sheaths and hair follicles, and provides energy for hair roots, thereby prolonging the growth cycle of hair.
The ginsenoside has scalp protecting effect, can be used for caring scalp, and is beneficial for promoting hair follicle proliferation.
The ginger root extract has anti-inflammatory and antioxidant effects, and can promote blood circulation, accelerate scalp metabolism, nourish hair, dredge hair follicle, deeply clean scalp, and stimulate hair growth in shampoo.
The lavender has effects of caring hair, cleaning, promoting scalp cell regeneration, balancing scalp oil secretion, and preventing hair follicle damage caused by oily skin.
In the embodiment, the plant composite anti-hair-loss agent is applied to shampoo, has a high-efficiency anti-hair-loss effect under the synergistic effect of various plant extracts, and is safer and more environment-friendly and milder to scalp compared with a chemical anti-hair-loss hair-growing agent; in addition, according to the preparation method disclosed by the invention, the prepared shampoo can retain the effective components on the scalp in the components, so that the effective components cannot be damaged in the processing process, and the obtained product has stable performance and is suitable for large-scale production.
Detailed Description
The present invention will be described in detail with reference to the following embodiments in order to make the aforementioned objects, features and advantages of the invention more comprehensible. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein.
The term "prepared from …" as used herein is synonymous with "comprising". The terms "comprises," "comprising," "includes," "including," "has," "having," "contains," "containing," or any other variation thereof, as used herein, are intended to cover a non-exclusive inclusion. For example, a composition, process, method, article, or apparatus that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, process, method, article, or apparatus.
When an amount, concentration, or other value or parameter is expressed as a range, preferred range, or as a range of upper preferable values and lower preferable values, this is to be understood as specifically disclosing all ranges formed from any pair of any upper range limit or preferred value and any lower range limit or preferred value, regardless of whether ranges are separately disclosed. For example, when a range of "1 to 5" is disclosed, the described range should be interpreted to include the ranges "1 to 4", "1 to 3", "1 to 2 and 4 to 5", "1 to 3 and 5", and the like. When a range of values is described herein, unless otherwise stated, the range is intended to include the endpoints thereof and all integers and fractions within the range.
In addition, the indefinite articles "a" and "an" preceding an element or component of the invention are not intended to limit the number requirement (i.e., the number of occurrences) of the element or component. Thus, "a" or "an" should be read to include one or at least one, and the singular form of an element or component also includes the plural unless the stated number clearly indicates that the singular form is intended.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
Example 1
A shampoo containing a plant composite anti-release agent comprises, by weight, 8% of the plant composite anti-release agent, 16% of sodium laureth sulfate, 7% of cocamidopropyl betaine, 2% of octyl/decyl glucoside, 1% of ethylene glycol distearate, 3% of polydimethylsiloxane, 0.3% of guar hydroxypropyl trimethyl ammonium chloride, 8% of the composite plant anti-release agent, 1.8% of cocamide MEA (MEA), 0.2% of acrylic acid/C10-30 alkanol acrylate cross-linked polymer, 0.2% of methyl hydroxybenzoate, 0.6% of phenoxyethanol, 0.2% of chlorphenesin, 0.5% of essence and the balance of deionized water; the plant composite anti-dropping agent comprises a coffee extract, a ginseng extract, a ginger root extract and a lavender extract, and specifically, the weight ratio of the caffeine extract to the ginseng extract to the ginger root extract to the lavender extract is 50:30:10: 10.
Further, the preparation method of the plant composite anti-shedding agent comprises the following steps:
s1: weighing the coffee extract, the ginseng extract, the ginger root extract and the lavender extract according to the weight ratio;
s2: adding 10 times of 70% ethanol into the weighed raw material components, decocting and refluxing for 3 times, each time for 1h, filtering, and combining the 3 times of filtrates;
s3: putting the filtrate obtained in the step S2 into a freezing centrifuge for centrifugation, and taking supernatant, wherein the rotating speed of the freezing centrifuge is 5000 rpm/min;
s4: recovering ethanol in the supernatant, making into fluid extract, and diluting with water to obtain plant composite anticreep agent with concentration of 1g/L for use.
Further, the prepared plant composite anti-hair loss agent is applied to shampoo, wherein the preparation method of the shampoo containing the plant composite anti-hair loss agent comprises the following steps:
s1: adding a proper amount of deionized water into a container, heating to 45 ℃ in a water bath, dispersing the acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer with water in advance, adding the dispersed polymer into the container, heating to 80 ℃, and stirring at constant temperature until the polymer is completely dissolved;
s2: adding the sodium laureth sulfate, the cocamide MEA and the methylparaben, keeping the temperature at 80 ℃, and stirring until the sodium laureth sulfate, the cocamide MEA and the methylparaben are completely dissolved;
s3: pre-dispersing the guar gum hydroxypropyl trimethyl ammonium chloride with water, adding the guar gum hydroxypropyl trimethyl ammonium chloride into a container, and stirring until the guar gum hydroxypropyl trimethyl ammonium chloride is completely dissolved;
s4: cooling to 55 deg.C, adding said cocamidopropyl betaine and said octyl/decyl glucoside, stirring until completely dissolved;
s5: cooling to 45 ℃, adding the polydimethylsiloxane, and rapidly stirring until the mixture is completely uniform;
s6: adding the ethylene glycol distearate, the phenoxyethanol, the chlorphenesin, the essence, the plant composite anti-shedding agent and the balance of deionized water, thoroughly and uniformly stirring, adjusting the pH to 5.6, and standing.
Example 2
This example differs from example 1 in that the weight ratio of the caffeine extract, the ginseng extract, the ginger root extract and the lavender extract is 25:25:25: 10.
Example 3
This example differs from example 1 in that the weight ratio of the caffeine extract, the ginseng extract, the ginger root extract and the lavender extract is 40:30:20: 10.
Example 4
This example differs from example 1 in that the weight ratio of the caffeine extract, the ginseng extract, the ginger root extract and the lavender extract is 30:30:30: 10.
Example 5
This example differs from example 1 in that the weight ratio of the caffeine extract, the ginseng extract, the ginger root extract and the lavender extract is 20:20:30: 5.
Example 6
This example differs from example 1 in that the weight ratio of the caffeine extract, the ginseng extract, the ginger root extract and the lavender extract is 20:35:15: 10.
Example 7
This example is different from example 1 in that the amount of the plant composite anticreep agent added to shampoo was 2%.
Example 8
This example is different from example 1 in that the amount of the plant composite anticreep agent added to shampoo was 4%.
Example 9
This example is different from example 1 in that the amount of the plant composite anticreep agent added to shampoo was 6%.
Example 10
This example is different from example 1 in that the amount of the plant composite anticreep agent added to shampoo was 10%.
Example 11
This example differs from example 1 by including 8% of the plant complex release inhibitor, 15% sodium laureth sulfate, 1% cocamidopropyl betaine, 1% octyl/decyl glucoside, 1% ethylene glycol distearate, 1% polydimethylsiloxane, 0.1% guar hydroxypropyltrimonium chloride, 1.0% cocamide MEA, 0.1% acrylic acid/C10-30 alkanol acrylate crosspolymer, 0.1% methylparaben, 0.1% phenoxyethanol, 0.1% chlorphenesin, 0.1% perfume, and the balance deionized water.
Example 12
This example differs from example 1 by including 8% of the plant complex release inhibitor, 25% sodium laureth sulfate, 10% cocamidopropyl betaine, 5% octyl/decyl glucoside, 3% ethylene glycol distearate, 5% polydimethylsiloxane, 0.5% guar hydroxypropyltrimonium chloride, 2.0% cocamide MEA, 0.5% acrylic acid/C10-30 alkanol acrylate crosspolymer, 0.5% methylparaben, 1.0% phenoxyethanol, 0.5% chlorphenesin, 0.5% perfume, and the balance deionized water.
Further, the preparation method of the shampoo containing the plant compound anti-release agent comprises the following steps:
s1: adding a proper amount of deionized water into a container, heating to 55 ℃ in a water bath, dispersing the acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer with water in advance, adding the dispersed polymer into the container, heating to 85 ℃, and stirring at constant temperature until the polymer is completely dissolved;
s2: adding the sodium laureth sulfate, the cocamide MEA and the methylparaben, keeping the temperature at 85 ℃, and stirring until the sodium laureth sulfate, the cocamide MEA and the methylparaben are completely dissolved;
s3: pre-dispersing the guar gum hydroxypropyl trimethyl ammonium chloride with water, adding the guar gum hydroxypropyl trimethyl ammonium chloride into a container, and stirring until the guar gum hydroxypropyl trimethyl ammonium chloride is completely dissolved;
s4: cooling to 60 ℃, adding the cocamidopropyl betaine and the octyl/decyl glucoside, and stirring until complete dissolution;
s5: cooling to 45 ℃, adding the polydimethylsiloxane, and rapidly stirring until the mixture is completely uniform;
s6: adding the ethylene glycol distearate, the phenoxyethanol, the chlorphenesin, the essence, the plant composite anti-shedding agent and the balance of deionized water, thoroughly and uniformly stirring, adjusting the pH to 6.5, and standing.
Comparative example 1
The comparative example is different from example 1 in that the addition amount of the phytocomplex anti-release agent in shampoo was 1%.
Comparative example 2
This comparative example is different from example 1 in that the shampoo was free of the phytocomplex anti-shedding agent.
Comparative example 3
The comparative example is different from example 1 in that the plant composite anti-alopecia agent includes a ginseng extract, a ginger root extract and a lavender extract, and the weight ratio of the ginseng extract, the ginger root extract and the lavender extract is 40:30: 30.
Comparative example 4:
the comparative example is different from example 1 in that the plant composite anti-dropping agent comprises caffeine extract, ginger root extract and lavender extract, and the weight ratio of the caffeine extract to the ginger root extract to the lavender extract is 50:30: 20.
Comparative example 5:
the comparative example is different from example 1 in that the plant composite anti-dropping agent includes caffeine extract, ginseng extract and lavender extract at a weight ratio of 50:30: 20.
(one) human body test
200 volunteers aged 25-55 years were selected, wherein 100 male and 100 female patients all had the following symptoms of moderate or more alopecia.
Uniformly distributing tables to trial personnel, wherein each group of 20 people has uniform distribution of age, sex and hair loss degree; the hair washing period is 2 days and 1 time during the test, the dosage of the shampoo is 5mL-10mL each time, the hair is washed and rubbed for 2min-5min each time, and then the water is flushed, and the trial time is 2 months. After the trial, the results were recovered by the technician and statistically analyzed, as shown in table 1:
TABLE 1
Figure BDA0003406666380000081
Figure BDA0003406666380000091
Among them, very satisfactory: the hair loss prevention effect is obvious; and (3) satisfaction: the hair loss prevention effect is general; is barely accepted: the alopecia prevention effect is not obvious; very unsatisfactory: indicating no retaining effect.
As can be seen from table 1, most of the test subjects had satisfactory hair loss prevention effects in example 1, while the shampoo containing no plant composite anti-hair loss agent had unsatisfactory hair loss prevention effects after being used by most of the test subjects.
In the above examples, the raw material ratio of the plant composite anticreep agent in examples 2-6 is different from that in example 1, and the anticreep effect is obviously inferior to that in example 1; secondly, as compared with examples 7 to 10 and comparative example 1, it is understood that the higher the proportion of the plant composite anti-hair loss agent added into shampoo is, the more obvious the anti-hair loss effect is, and when the proportion is more than 8%, the anti-hair loss effect is rather reduced, but the anti-hair loss effect is basically satisfactory for the testers; the shampoo in the comparative example 2 is not added with the plant composite anti-hair loss agent, and has no or very weak anti-hair loss effect after being used; finally, the phytocomplex anticreep agent of comparative example 3 lacks caffeine extract compared to example 1, the phytocomplex anticreep agent of comparative example 4 lacks ginseng extract compared to example 1, and the phytocomplex anticreep agent of comparative example 5 lacks ginger root extract compared to example 1, and it can be seen from the results that the anticreep effect of comparative examples 3-5 is significantly insufficient, demonstrating that the phytocomplex anticreep agent consisting of caffeine extract, ginseng extract, ginger root extract and lavender extract in the present invention can provide a synergistic anticreep effect.
In conclusion, when the weight ratio of the caffeine extract to the ginseng extract to the ginger root extract to the lavender extract is 50:30:10:10, and the addition amount of the caffeine extract to the ginseng extract to the ginger root extract to the lavender extract is 8%, a good anti-hair loss effect can be achieved.
In the embodiment, the plant composite anti-hair-loss agent is applied to shampoo, has high-efficiency anti-hair-loss effect under the synergistic action of various plant extracts, is safer and more environment-friendly compared with a chemical anti-hair-loss hair-growing agent, and has milder effect on scalp; in addition, according to the preparation method disclosed by the invention, the prepared shampoo can retain the effective components on the scalp in the components, so that the effective components cannot be damaged in the processing process, and the obtained product has stable performance and is suitable for large-scale production.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (8)

1. A shampoo containing a plant composite anti-release agent is characterized by comprising, by weight, 1% -10% of the plant composite anti-release agent, 15% -25% of sodium laureth sulfate, 1% -10% of cocamidopropyl betaine, 1% -5% of octyl/decyl glucoside, 1% -3% of ethylene glycol distearate, 1% -5% of polydimethylsiloxane, 0.1% -0.5% of guar hydroxypropyltrimonium chloride, 1.0% -2.0% of cocamide MEA (membrane electrode assembly), 0.1% -0.5% of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.1% -0.5% of methyl hydroxybenzoate, 0.1% -1.0% of phenoxyethanol, 0.1% -0.5% of chlorphenesin, 0.1% -0.5% of essence and the balance of deionized water,
the plant composite anti-dropping agent comprises 20-50% of coffee extract, 20-35% of ginseng extract, 10-30% of ginger root extract and 1-10% of lavender extract.
2. The shampoo containing the plant composite anti-dropping agent as claimed in claim 1, wherein the plant composite anti-dropping agent comprises 30-40% of coffee extract, 20-30% of ginseng extract, 15-20% of ginger root extract and 5-10% of lavender extract.
3. The shampoo containing the plant composite anti-release agent as claimed in claim 1, wherein the weight ratio of the caffeine extract to the ginseng extract to the ginger root extract to the lavender extract is 50:30:10: 10.
4. The shampoo containing the plant composite anti-release agent as claimed in any one of claims 1 to 3, wherein the preparation method of the plant composite anti-release agent comprises the following steps:
s1: weighing the coffee extract, the ginseng extract, the ginger root extract and the lavender extract according to the weight ratio;
s2: adding 10 times of 70% ethanol into the weighed raw material components, decocting and refluxing for 3 times, each time for 1h, filtering, and combining the 3 times of filtrates;
s3: putting the filtrate obtained in the step S2 into a freezing centrifuge for centrifugation, and taking supernatant, wherein the rotating speed of the freezing centrifuge is 5000 rpm/min;
s4: recovering ethanol from the supernatant, making the obtained supernatant into fluid extract, and diluting with water to obtain plant composite anticreep agent with concentration of 1g/L for use.
5. The shampoo containing the plant composite anti-release agent as claimed in claim 4, wherein the addition amount of the plant composite anti-release agent in the shampoo is 5% -8%.
6. The shampoo containing plant complex release preventive as claimed in claim 5, wherein the shampoo containing plant complex release preventive comprises 8% of the plant complex release preventive, 16% of sodium laureth sulfate, 7% of cocamidopropyl betaine, 2% of octyl/decyl glucoside, 1% of ethylene glycol distearate, 3% of polydimethylsiloxane, 0.3% of guar hydroxypropyltrimonium chloride, 1.8% of cocamide MEA, 0.2% of acrylic acid/C10-30 alkanol acrylate crosspolymer, 0.2% of methyl hydroxybenzoate, 0.6% of phenoxyethanol, 0.2% of chlorphenesin, 0.5% of essence, and the balance of deionized water.
7. A preparation method of shampoo containing plant composite anti-release agent according to any one of claims 1-6, characterized by comprising the following steps:
s1: adding a proper amount of deionized water into a container, heating to 45-55 ℃ in a water bath, dispersing the acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer in water in advance, adding the mixture into the container, heating to 80-85 ℃, and stirring at constant temperature until the acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer is completely dissolved;
s2: adding the sodium laureth sulfate, the cocamide MEA and the methylparaben, keeping the temperature between 80 and 85 ℃, and stirring until the sodium laureth sulfate, the cocamide MEA and the methylparaben are completely dissolved;
s3: pre-dispersing the guar gum hydroxypropyl trimethyl ammonium chloride with water, adding the guar gum hydroxypropyl trimethyl ammonium chloride into a container, and stirring until the guar gum hydroxypropyl trimethyl ammonium chloride is completely dissolved;
s4: cooling to 55-60 ℃, adding the cocamidopropyl betaine and the octyl/decyl glucoside, and stirring until complete dissolution;
s5: cooling to 45 ℃, adding the polydimethylsiloxane, and rapidly stirring until the mixture is completely uniform;
s6: adding the ethylene glycol distearate, the phenoxyethanol, the chlorphenesin, the essence, the plant composite anti-shedding agent and the balance of deionized water, thoroughly and uniformly stirring, adjusting the pH, and standing.
8. The shampoo containing the plant composite anti-release agent as claimed in claim 7, wherein the pH is 5.6-6.5.
CN202111515163.XA 2021-12-13 2021-12-13 Shampoo containing plant composite anti-shedding agent and preparation method thereof Pending CN113995709A (en)

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Application publication date: 20220201