CN113952472A - 用于治疗眼部疾病的组合物和方法 - Google Patents
用于治疗眼部疾病的组合物和方法 Download PDFInfo
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- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0306—Animal model for genetic diseases
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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| CN202010705069.XA CN113952472A (zh) | 2020-07-21 | 2020-07-21 | 用于治疗眼部疾病的组合物和方法 |
| EP21845856.0A EP4185319A4 (en) | 2020-07-21 | 2021-07-20 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF OPHTHALMIC DISEASES |
| CN202180064480.6A CN116615552A (zh) | 2020-07-21 | 2021-07-20 | 用于治疗眼疾病的组合物和方法 |
| PCT/IB2021/000509 WO2022018518A1 (en) | 2020-07-21 | 2021-07-20 | Compositions and methods for the treatment of eye diseases |
| CA3186826A CA3186826A1 (en) | 2020-07-21 | 2021-07-20 | Compositions and methods for the treatment of eye diseases |
| AU2021312379A AU2021312379A1 (en) | 2020-07-21 | 2021-07-20 | Compositions and methods for the treatment of eye diseases |
| JP2023512665A JP2023542279A (ja) | 2020-07-21 | 2021-07-20 | 眼疾患の処置のための組成物および方法 |
| US18/157,589 US20230321281A1 (en) | 2020-07-21 | 2023-01-20 | Compositions and methods for the treatment of eye diseases |
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| CN202010705069.XA CN113952472A (zh) | 2020-07-21 | 2020-07-21 | 用于治疗眼部疾病的组合物和方法 |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2507036A1 (en) * | 2002-12-02 | 2004-06-17 | Genvec, Inc. | Materials and methods for treating ocular-related disorders |
| CN105940109A (zh) * | 2013-12-06 | 2016-09-14 | 国立健康与医学研究所 | 用于在受试者的视网膜色素上皮中表达目的多核苷酸的方法和药物组合物 |
| CN105980569A (zh) * | 2013-08-05 | 2016-09-28 | 莱顿大学医学中心附属莱顿教学医院 | 重组aav-crumbs同源物组合物及治疗lca-8和进行性rp的方法 |
| CN108699118A (zh) * | 2015-09-10 | 2018-10-23 | 牛津大学创新有限公司 | 色素性视网膜炎的治疗 |
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| JP6199965B2 (ja) * | 2012-07-11 | 2017-09-20 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | Rpgrx連鎖性網膜変性のaav媒介型遺伝子治療 |
| JP5971661B2 (ja) * | 2012-09-19 | 2016-08-17 | 国立大学法人 東京大学 | 神経活動依存的プロモータ活性を有するdna、及びこれを含むベクター |
| CA2945965C (en) * | 2014-04-15 | 2022-11-01 | Applied Genetic Technologies Corporation | Codon optimized nucleic acid encoding a retinitis pigmentosa gtpase regulator (rpgr) |
| LT3137497T (lt) * | 2014-05-02 | 2021-07-26 | Genzyme Corporation | Aav vektoriai, skirti tinklainės ir cns genų terapijai |
| KR20230039779A (ko) * | 2016-07-29 | 2023-03-21 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 변이체 캡시드를 갖는 아데노-관련된 바이러스 비리온 및 이의 사용 방법 |
| CN110461368A (zh) * | 2017-06-30 | 2019-11-15 | 加利福尼亚大学董事会 | 具有变异衣壳的腺相关病毒病毒体及其使用方法 |
| KR102824021B1 (ko) * | 2018-01-31 | 2025-06-24 | 더 리서치 인스티튜트 앳 네이션와이드 칠드런스 하스피탈 | 2c형 지대근이영양증에 대한 유전자 치료 |
| JOP20210054A1 (ar) * | 2018-09-21 | 2020-03-21 | Nightstarx Ltd | تركيبات وطرق لعلاج التهاب الشبكية الصباغي |
| EP4087617A4 (en) * | 2020-01-10 | 2024-05-01 | Solid Biosciences Inc. | VIRAL VECTOR FOR COMBINATION THERAPY |
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Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| US20230321281A1 (en) | 2023-10-12 |
| EP4185319A4 (en) | 2024-12-04 |
| JP2023542279A (ja) | 2023-10-06 |
| CA3186826A1 (en) | 2022-01-27 |
| EP4185319A1 (en) | 2023-05-31 |
| WO2022018518A1 (en) | 2022-01-27 |
| AU2021312379A1 (en) | 2023-03-23 |
| CN116615552A (zh) | 2023-08-18 |
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