CN113926223A

CN113926223A - Heparin sodium crude precipitation equipment

Info

Publication number: CN113926223A
Application number: CN202111227717.6A
Authority: CN
Inventors: 黄帅; 陈佳彤; 佟以涛; 徐袁; 蔡顺东
Original assignee: Huangchuan Pengsheng Livestock Products Co ltd
Current assignee: Huangchuan Pengsheng Livestock Products Co ltd
Priority date: 2021-10-21
Filing date: 2021-10-21
Publication date: 2022-01-14

Abstract

The invention discloses heparin sodium crude product precipitation equipment, relates to the technical field of crude product heparin sodium refining, and aims to solve the problems that when the existing heparin sodium crude product raw material is subjected to low-power precipitation, the raw material is usually placed in a precipitation tank, but the tank body is usually of a slender structure so as to be conveniently matched with a stirring shaft for mixing materials in consideration of mixing uniformity, the raw material is easily influenced by end effect and interference precipitation in the subsequent precipitation process due to the container, and the precipitation efficiency is reduced. The improved garbage collection and drying device is characterized in that a first frame is installed above one side of the collecting box placing plate, a second frame is installed above the other side of the collecting box placing plate, an electric cabinet is installed on the outer wall of the second frame, a belt protection cover is installed on the outer wall of the first frame, a stirring chamber is arranged between the first frame and the second frame, and the two sides of the stirring chamber are rotatably connected with the first frame and the second frame through transmission shafts.

Description

Heparin sodium crude precipitation equipment

Technical Field

The invention relates to the technical field of refining of crude heparin sodium, in particular to heparin sodium crude product precipitation equipment.

Background

Heparin sodium is the glycosaminoglycan compound with the most complex molecular structure known so far, products for clinical application at present comprise heparin sodium, series of low molecular heparin and the like, and required raw materials can only be extracted from small intestinal mucosa of pigs. The raw material of the heparin raw material drug is a heparin crude product, the extraction of the heparin crude product can only be from the small intestinal mucosa of healthy live pigs, and the heparin raw material drug is prepared by directionally obtaining the heparin with complete natural structural groups through physical and chemical extraction and separation processes because the heparin crude product contains a large amount of impurities such as impurity proteins, impurity nucleic acids, microorganisms and the like. In the refining process of the heparin sodium crude product, the steps of dissolving, enzymolysis, acid treatment, low-temperature centrifugation, oxidation, low-time precipitation, drying and the like are required to be carried out on the crude product to quickly reduce the impurity load so as to prepare the refined heparin sodium.

However, when the existing heparin sodium crude product raw material is subjected to low-power precipitation, the raw material is usually placed in a precipitation tank for precipitation, but the tank body is usually of a slender structure in consideration of mixing uniformity so as to be conveniently matched with a stirring shaft for mixing materials, and the raw material is easily influenced by end effect and interference precipitation in the subsequent precipitation process by the container, so that the precipitation efficiency is reduced; therefore, we propose a crude heparin sodium precipitation apparatus in order to solve the problems mentioned above.

Disclosure of Invention

The invention aims to provide heparin sodium crude product precipitation equipment to solve the problems that the existing heparin sodium crude product raw material in the background art is usually placed in a precipitation tank for low-power precipitation, but the tank body is usually of a slender structure to be convenient to match with a stirring shaft for mixing materials in consideration of mixing uniformity, and the raw material is easily influenced by end effect and interference sedimentation in the subsequent precipitation process due to the container, so that the precipitation efficiency is reduced.

In order to achieve the purpose, the invention provides the following technical scheme: the heparin sodium crude product precipitation equipment comprises a collecting box placing plate, wherein a first rack is installed above one side of the collecting box placing plate, a second rack is installed above the other side of the collecting box placing plate, an electric cabinet is installed on the outer wall of the second rack, a belt protection cover is installed on the outer wall of the first rack, a stirring chamber is arranged between the first rack and the second rack, two sides of the stirring chamber are rotatably connected with the first rack and the second rack through transmission shafts, a precipitation chamber is installed at the lower end of the stirring chamber, the upper end of the precipitation chamber is connected with the lower end of the stirring chamber through a flange plate, a jacket is installed outside the precipitation chamber, an electromagnetic discharge valve is installed below the precipitation chamber, a gear transmission chamber is installed at the upper end of the stirring chamber, an electromagnetic discharge valve is arranged on one side of the gear transmission chamber, and a heat discharge mechanism is installed at the upper end of the electromagnetic discharge valve, the opposite side of gear drive room is provided with the feed valve, the hopper is installed to the upper end of feed valve, the hot plate support is all installed all around to the outer wall of teeter chamber, install the heating on the inner wall of hot plate support and lead the warm board, and the heating leads the inside that the warm board extends to the teeter chamber.

Preferably, the internally mounted of teeter chamber has the cavity pivot, install U-shaped stirring leaf on the outer wall of cavity pivot, and U-shaped stirring leaf and cavity pivot welded connection, two anchor bars are installed to U-shaped stirring leaf and well idle running shaft between, and the both ends of anchor bar respectively with U-shaped stirring leaf and well idle running shaft welded connection, the U-shaped stirring leaf can be better with the material contact in the teeter chamber, improve compounding efficiency.

Preferably, the one end of cavity pivot runs through the teeter chamber and extends to the outside of gear drive room, and installs water supply connector, install driven gear on the outer wall of cavity pivot upper end, and driven gear sets up the inside at the gear drive room, one side of driven gear is provided with the driving gear, and driven gear is connected with driving gear engagement, install asynchronous machine on the outer wall of gear drive room, asynchronous machine's output runs through and extends to the inside of gear drive room, and is connected with driving gear transmission, and asynchronous machine's output can rely on gear structure to drive the U-shaped stirring leaf rotation of cavity pivot and outer wall, mixes the material.

Preferably, the lower extreme of cavity pivot is installed and is washd the dish, the upper surface and the lower surface of wasing the dish all are provided with arc lid, upper surface be provided with the heat preservation on the outer wall of arc lid, be provided with the heat preservation inside lining on the inner wall of teeter chamber, the outer wall of wasing the dish is provided with six contrary nozzles all around, washs the dish after leading-in water, can rely on six outside to end contrary nozzles with water spray to the container inner wall for cleaning process convenient and fast more.

Preferably, the liquid inlet is installed to the top of pressing from both sides the cover one side outer wall, the liquid mouth that returns is installed to the below of pressing from both sides the cover opposite side outer wall, the inside of pressing from both sides the cover is provided with the refrigeration chamber, the internally mounted in refrigeration chamber has annular radiating fin, and annular radiating fin and the outer wall welded connection of drip chamber, presss from both sides the cover and can be through external cold water machine, to the leading-in cooling water of refrigeration intracavity and carry out cooling treatment to the material.

Preferably, a PH value sensor is installed to one side of drip chamber upper end, and the inside that the one end of PH value sensor runs through and extends to the drip chamber, and the PH value sensor can detect the PH value of material, conveniently adjusts.

Preferably, the internally mounted of heat extraction mechanism has electric motor, five exhaust fan blades are installed on electric motor's the output, the gauze is installed to heat extraction mechanism's upper end, install the metal mesh on the outer wall of gauze, heat extraction mechanism can rely on built-in exhaust fan, discharges the heat of gathering in the teeter chamber fast.

Preferably, the internally mounted of heating temperature guide plate has electric heating wire, the externally mounted of hot plate support connects the electricity ring, connect and install power supply connector on the outer wall of electricity ring, connect the electricity ring and can make things convenient for four groups of heating temperature guide plates to connect the electricity.

Preferably, upper strata liquid suction valve is installed to the front end of drip chamber top, the material level observation window is installed to the front end of drip chamber, one side of material level observation window is provided with the liquid level line, and the material level observation window can the audio-visual sediment material level of looking over.

Preferably, the bearing is installed with the junction of first frame and second frame to the transmission shaft, one side the transmission shaft runs through first frame and extends to the inside of belt safety cover, and installs from the driving wheel, the below from the driving wheel is provided with the action wheel, the action wheel passes through the rubber tape and is connected from the driving wheel transmission, install step motor on the outer wall of belt safety cover, step motor's output runs through and extends to the inside of belt safety cover, and is connected with the action wheel transmission, and step motor can rely on the position of belt transmission structure transfer deposit room and teeter chamber.

Compared with the prior art, the invention has the beneficial effects that:

1. the invention arranges the stirring chamber and the settling chamber in the container, the container can realize turnover through the stepping motor and the belt transmission structure, when in stirring, the stirring chamber is arranged below, the settling chamber is arranged above, the stirring chamber is of a slender structure, the lining is provided with the heat insulation layer, thereby being more convenient for the stirring blades to contact with the material in a large area, ensuring the efficiency of material mixing and heating, when in settling, the positions of the stirring chamber and the settling chamber can be adjusted to enable the material liquid to fall into the settling chamber, because the heating structure is arranged in the stirring chamber, the settling chamber can better exchange heat and cold, quickly cool the material, and enable the material to better settle, the settling chamber is of a flat structure as a whole, compared with the slender stirring chamber, the distance from the sediment to the bottom surface is shorter, the gap between the material particles is larger, the distance from the peripheral wall surface is farther, and the influence caused by interference settling and end effect is reduced, the settling rate is accelerated, so that the problem that the settling efficiency is reduced because the raw material is easily influenced by end effect and interference settling in the subsequent settling process due to the fact that the tank body is usually of a long and thin structure so as to be conveniently matched with a stirring shaft for mixing materials and the like because the mixing uniformity is considered when the existing heparin sodium crude raw material is subjected to low-power settling is solved.

2. Through set up four embedded heating of group and lead the warm board in the teeter chamber, warm board internally mounted is led in the heating has electric heating wire, compares in traditional outer wall heating, and the internal heating can even efficient and feed liquid contact more, by interior and give off the heat outward to rely on the heat preservation inside lining to pin the heat, thereby improved heating efficiency.

3. Through the cooling mode that adopts clamp cover and heat extraction mechanism to combine together, when cooling, only need toward inserting external water-cooling machine on the clamp cover, to the leading-in cooling water of refrigeration intracavity, can carry out cooling treatment to the feed liquid, the inside multiunit annular radiating fin that is provided with of clamp cover, can be with the heat rapid conduction to the fin of feed liquid in the container, conveniently carry out the heat exchange with the cooling water, refrigeration efficiency has been showing and promoted, open heat extraction mechanism in the refrigerated, can rely on built-in exhaust fan, discharge the heat of accumulating in the teeter chamber fast, supplementary promotion cooling efficiency, the heating structure of container only sets up in the teeter chamber, when deposiing, teeter chamber and deposit room position transfer, make the material break away from the teeter chamber naturally, make things convenient for its better and carry out the heat exchange cooling with the deposit chamber, thereby showing and promoting cooling efficiency.

4. After one-time material discharging is finished, clean water can enter the cleaning disc along the rotating shaft cavity through the water inlet joint at the upper end of the middle idle shaft, is sprayed out from six non-return nozzles at the periphery and is uniformly sprayed on the inner wall of the settling chamber to be cleaned well, and after a certain amount of water is in the container, the stepper motor can be driven to drive the container to turn over, so that the water flows in the stirring chamber and the settling chamber in a reciprocating manner, the cleaning efficiency of the container is obviously improved, and the next refining can be conveniently and quickly carried out.

Drawings

FIG. 1 is a schematic view of the overall structure of the present invention;

FIG. 2 is a schematic view of the internal structure of the stirring chamber and the settling chamber of the present invention;

FIG. 3 is a schematic view of the internal structure of a jacket according to the present invention;

FIG. 4 is a schematic view of the internal structure of the heat removal mechanism of the present invention;

FIG. 5 is a cross-sectional view of the structure at A of the present invention;

FIG. 6 is a schematic view of a driveshaft connection of the present invention;

FIG. 7 is a schematic top view of the cleaning disc of the present invention;

in the figure: 1. a collecting box placing plate; 2. a first frame; 3. a second frame; 4. an electric cabinet; 5. a belt guard; 6. a stepping motor; 7. a stirring chamber; 8. a drive shaft; 9. a bearing; 10. a settling chamber; 11. a flange plate; 12. a heating plate support; 13. a gear drive chamber; 14. a water inlet joint; 15. an asynchronous motor; 16. a feed valve; 17. a hopper; 18. an electromagnetic heat release valve; 19. a heat removal mechanism; 20. an electromagnetic discharge valve; 21. a jacket; 22. a material level observation window; 23. a liquid level line; 24. a liquid inlet; 25. a liquid return port; 26. a pH value sensor; 27. a supernatant suction valve; 28. a power connection ring; 29. a power supply connector; 30. a refrigeration cavity; 31. an annular heat dissipation fin; 32. heating the heat conducting plate; 33. an electric heating wire; 34. insulating the inner lining; 35. a hollow rotating shaft; 36. a U-shaped stirring blade; 37. a reinforcing rod; 38. cleaning the disc; 39. an arc-shaped cover; 40. a non-return nozzle; 41. an electric motor; 42. an exhaust fan blade; 43. a screen; 44. a metal mesh; 45. a driven gear; 46. a driving gear; 47. a driving wheel; 48. a driven wheel; 49. a rubber belt; 50. and (7) an insulating layer.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.

Referring to fig. 1-7, an embodiment of the present invention is shown: the heparin sodium crude product precipitation equipment comprises a collecting box placing plate 1, a first rack 2 is arranged above one side of the collecting box placing plate 1, a second rack 3 is arranged above the other side of the collecting box placing plate 1, an electric cabinet 4 is arranged on the outer wall of the second rack 3, a belt protective cover 5 is arranged on the outer wall of the first rack 2, a stirring chamber 7 is arranged between the first rack 2 and the second rack 3, two sides of the stirring chamber 7 are rotatably connected with the first rack 2 and the second rack 3 through a transmission shaft 8, a precipitation chamber 10 is arranged at the lower end of the stirring chamber 7, the upper end of the precipitation chamber 10 is connected with the lower end of the stirring chamber 7 through a flange plate 11, a jacket 21 is arranged outside the precipitation chamber 10, an electromagnetic discharge valve 20 is arranged below the precipitation chamber 10, a gear transmission chamber 13 is arranged at the upper end of the stirring chamber 7, an electromagnetic discharge valve 18 is arranged on one side of the gear transmission chamber 13, a heat discharging mechanism 19 is installed at the upper end of the electromagnetic heat discharging valve 18, a feeding valve 16 is arranged on the other side of the gear transmission chamber 13, a hopper 17 is installed at the upper end of the feeding valve 16, a heating plate support 12 is installed on the periphery of the outer wall of the stirring chamber 7, a heating heat conducting plate 32 is installed on the inner wall of the heating plate support 12, and the heating heat conducting plate 32 extends to the inside of the stirring chamber 7.

Further, the internally mounted of teeter chamber 7 has cavity pivot 35, install U-shaped stirring leaf 36 on the outer wall of cavity pivot 35, and U-shaped stirring leaf 36 and cavity pivot 35 welded connection, install two reinforcing bars 37 between U-shaped stirring leaf 36 and the well idle running shaft 35, and the both ends of reinforcing bar 37 respectively with U-shaped stirring leaf 36 and well idle running shaft 35 welded connection, teeter chamber 7 adopts U-shaped stirring leaf 36 to mix the material, it is big with material area of contact, mixing efficiency is high, the structural length of rabbling mechanism can be showing in the setting of reinforcing bar 37 structure, make its compounding work that is applicable to big batch material.

Further, the one end of cavity pivot 35 runs through teeter chamber 7 and extends to the outside of gear drive room 13, and install water supply connector 14, install driven gear 45 on the outer wall of cavity pivot 35 upper end, and driven gear 45 sets up the inside at gear drive room 13, one side of driven gear 45 is provided with driving gear 46, and driven gear 45 is connected with driving gear 46 meshing, install asynchronous motor 15 on the outer wall of gear drive room 13, asynchronous motor 15's output runs through and extends to the inside of gear drive room 13, and be connected with driving gear 46 transmission, asynchronous motor 15's output can drive driving gear 46 rotatory, make driving gear 46 and driven gear 45 mesh, it is rotatory to drive the cavity pivot 35 on the driven gear 45 simultaneously, drive the U-shaped stirring leaf 36 mixed material of cavity pivot 35 outer wall.

Further, a cleaning disc 38 is installed at the lower end of the hollow rotating shaft 35, arc-shaped covers 39 are arranged on the upper surface and the lower surface of the cleaning disc 38, a heat insulation layer 50 is arranged on the outer wall of the upper surface arc-shaped cover 39, a heat insulation lining 34 is arranged on the inner wall of the stirring chamber 7, six check nozzles 40 are arranged around the outer wall of the cleaning disc 38, the arc-shaped covers 39 on the upper surface and the lower surface of the cleaning disc 38 can facilitate the circulation of material liquid and avoid deposition and accumulation, the heat insulation layer 50 is arranged on the outer wall of the upper surface arc-shaped cover 39 and is matched with the heat insulation lining 34 on the inner wall of the stirring chamber 7, so that when the material liquid enters the stirring chamber 7 for heating, a better heat insulation effect is achieved, the heat is prevented from being dissipated too fast, the heating efficiency is remarkably improved, and the cleaning disc 38 can be connected with a water pipe through a water inlet joint 14 at the upper end of the middle idle rotating shaft 35 after one-time deposition is completed, so that clean water enters the cleaning disc 38 along the rotating shaft cavity, the water is sprayed out from the six non-return nozzles 40 around, and is uniformly sprayed on the inner wall of the settling chamber 10 to be better cleaned, and after a certain amount of water is arranged in the container, the stepping motor 6 can be driven to drive the container to turn over, so that the water flows in the stirring chamber 7 and the settling chamber 10 in a reciprocating manner, the cleaning efficiency of the container is obviously improved, and the next refining is conveniently and quickly carried out.

Further, inlet 24 is installed to the top of jacket 21 one side outer wall, liquid return port 25 is installed to the below of jacket 21 opposite side outer wall, the inside of jacket 21 is provided with refrigeration chamber 30, the internally mounted of refrigeration chamber 30 has annular radiating fin 31, and annular radiating fin 31 and the outer wall welded connection of drip chamber 10, after the feed liquid that the heating mixture finishes gets into drip chamber 10, can be connected inlet 24 and the liquid return port 25 of jacket 21 with the inlet tube and the wet return of external water-cooled generator respectively, thereby to leading-in cooling water in refrigeration chamber 30, carry out cooling process to the feed liquid, jacket 21 is inside to be provided with multiunit annular radiating fin 31, can conduct the heat of feed liquid in the container to the fin fast, conveniently carry out the heat exchange with the cooling water, show and promoted refrigeration efficiency.

Further, PH value sensor 26 is installed to one side of drip chamber 10 upper end, and the inside that extends to drip chamber 10 is run through to PH value sensor 26's one end, before crude heparin sodium feed liquid deposits, at first need adjust to the neutrality with the feed liquid that oxidation in-process, PH value is in 9-10, can acquire the current PH value of feed liquid fast through PH value sensor 26 for accommodation process is convenient and fast more.

Further, the internally mounted of heat extraction mechanism 19 has electric motor 41, install five exhaust fan blades 42 on electric motor 41's the output, gauze 43 is installed to heat extraction mechanism 19's upper end, install metal mesh 44 on gauze 43's the outer wall, at the refrigerated in-process of deposit, can open electromagnetic heat release valve 18 and heat extraction mechanism 19, rely on the inside exhaust fan of heat extraction mechanism 19, discharge the heat in the container fast, further promote device's cooling efficiency, gauze 43 on the heat extraction mechanism 19 can avoid outside dust to enter into inside the container, influence the refined quality of heparin sodium, and metal mesh 44 of gauze 43 outer wall can guarantee its structural strength.

Further, the internally mounted of heating temperature guide plate 32 has electric heating wire 33, the externally mounted of hot plate support 12 connects electrical ring 28, connect and install power supply connector 29 on electrical ring 28's the outer wall, heating temperature guide plate 32 is provided with four, and inside extending to teeter chamber 7, compare in traditional outer wall heating, internal heating can be more even efficient and feed liquid contact, from inside to outside give off heat, and rely on heat preservation inside lining 34 to pin the heat, thereby heating efficiency has been improved, the outside electricity connection ring 28 of hot plate support 12, can conveniently accomplish four group's heating temperature guide plate 32 connect the electric work.

Further, upper strata liquid suction valve 27 is installed to the front end of drip chamber 10 top, material level observation window 22 is installed to the front end of drip chamber 10, one side of material level observation window 22 is provided with liquid level line 23, material level observation window 22 can the audio-visual liquid level of looking over the precipitate, after the sediment is accomplished, upper strata liquid suction valve 27 can be opened, the end goes out the hose that the parcel has the filtration gauze and stretches into drip chamber 10 in, make the hose be located the material level top, thereby conveniently take out from the supernatant.

Further, bearing 9 is installed with the junction of first frame 2 and second frame 3 to transmission shaft 8, one side transmission shaft 8 runs through first frame 2 and extends to the inside of belt safety cover 5, and install from driving wheel 48, the below from driving wheel 48 is provided with action wheel 47, action wheel 47 passes through rubber tape 49 and is connected from driving wheel 48 transmission, install step motor 6 on the outer wall of belt safety cover 5, step motor 6's output runs through and extends to the inside of belt safety cover 5, and be connected with action wheel 47 transmission, when using the container, accessible step motor 6 and belt transmission structure drive the container upset, thereby through the upper and lower position of changing drip chamber 10 and teeter chamber 7, realize different functions.

The working principle is as follows: when the device is used, firstly, the stirring chamber 7 is kept in a lower state in the upper settling chamber 10, the feed valve 16 is opened, crude heparin sodium feed liquid after oxidation is poured into the container, the pH value of the current feed liquid is observed through the pH value sensor 26, a regulator is dripped at the material port to enable the feed liquid to be neutral, after the pH value is adjusted, the feed liquid is diluted, after the adjustment, eight percent of sodium chloride and 0.46 time of medicinal ethanol are added, then the feed valve 16 is closed, the stepping motor 6 is driven to drive the settling chamber 10 and the stirring chamber 7 to exchange positions, so that the feed liquid falls into the stirring chamber 7, then the electric heating wire 33 and the asynchronous motor 15 in the heating and temperature guiding plate 32 are started, the container heat is quickly lifted to 50-60 ℃ by utilizing the four groups of the heating and temperature guiding plate 32, and simultaneously the U-shaped stirring blade 36 on the outer wall of the hollow rotating shaft 35 is driven to rotate by the asynchronous motor 15 and the gear structure, because the whole stirring chamber 7 is of a long and thin structure, the contact area of the solution and the U-shaped stirring blades 36 is large, four groups of embedded heating and temperature guide plates 32 are used as baffle structures, vortex generation can be avoided, stirring is more uniform and efficient, after material mixing is finished, the stepping motor 6 is driven again to change the positions of the settling chamber 10 and the stirring chamber 7, so that the material liquid falls into the settling chamber 10, an external water cooler is connected onto a jacket 21 of the settling chamber 10, cooling water is introduced into a refrigeration cavity 30 to cool the material liquid, a plurality of groups of annular radiating fins 31 are arranged in the jacket 21, the heat of the material liquid in a container can be quickly transmitted to the fins, heat exchange with the cooling water is facilitated, the refrigeration efficiency is remarkably improved, the temperature of the solution is controlled to be 0-5 ℃, a better precipitation effect is achieved, and in the precipitation and cooling processes, the electromagnetic radiating valve 18 and the heat exhaust mechanism 19 at the upper end of the stirring chamber 7 can be opened, relying on the inside exhaust fan of heat extraction mechanism 19, discharge the heat in the container fast, the supplementary cooling efficiency that promotes, the whole flat structure of settling chamber 10, compare with slender stirring chamber 7, the distance of precipitate to the bottom surface is shorter, and the material granule clearance is bigger, and is farther apart from peripheral wall, has reduced the influence that the interference subsides and the end effect causes, and then has improved the efficiency of deposit, after the material deposit finishes, can look over the liquid level of precipitate directly perceivedly through material level observation window 22, can open supernatant suction valve 27 at this moment, stretch the end out the hose that wraps up the filtration gauze into settling chamber 10, make the hose be located the material level top, thus conveniently take out the supernatant, after the supernatant is taken out, open the electromagnetism baiting valve 20 of settling chamber 10 bottom and can take out the material, add ethanol suction filtration after grinding, can make the heparin sodium finished product after the finish machining, after finishing discharging, the accessible is toward the water supply connector 14 access pipe of idle running shaft 35 upper end, make in the clear water gets into washing dish 38 along the pivot chamber, spout from six contrary nozzles 40 all around, evenly spray on the inner wall of drip chamber 10, carry out better cleanness to it, and after container inside has a certain amount of water, can drive step motor 6 and drive the container upset, make the reciprocal circulation of water in teeter chamber 7 and drip chamber 10, show the clean efficiency that promotes the container, conveniently carry out the refining of next time fast.

It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Claims

1. Heparin sodium crude precipitation equipment places board (1), its characterized in that including the collecting box: the collecting box placing plate is characterized in that a first rack (2) is installed above one side of the collecting box placing plate (1), a second rack (3) is installed above the other side of the collecting box placing plate (1), an electric cabinet (4) is installed on the outer wall of the second rack (3), a belt protection cover (5) is installed on the outer wall of the first rack (2), a stirring chamber (7) is arranged between the first rack (2) and the second rack (3), two sides of the stirring chamber (7) are rotatably connected with the first rack (2) and the second rack (3) through transmission shafts (8), a settling chamber (10) is installed at the lower end of the stirring chamber (7), the upper end of the settling chamber (10) is connected with the lower end of the stirring chamber (7) through a flange plate (11), a jacket (21) is installed outside the settling chamber (10), and an electromagnetic discharging valve (20) is installed below the settling chamber (10), gear drive room (13) is installed to the upper end of teeter chamber (7), one side of gear drive room (13) is provided with electromagnetism exothermic valve (18), heat extraction mechanism (19) are installed to the upper end of electromagnetism exothermic valve (18), the opposite side of gear drive room (13) is provided with feed valve (16), hopper (17) are installed to the upper end of feed valve (16), hot plate support (12) are all installed all around to the outer wall of teeter chamber (7), install heating on the inner wall of hot plate support (12) and lead warm brakeite (32), and heat and lead warm brakeite (32) and extend to the inside of teeter chamber (7).

2. The crude heparin sodium precipitation apparatus according to claim 1, wherein: the internally mounted of teeter chamber (7) has cavity pivot (35), install U-shaped stirring leaf (36) on the outer wall of cavity pivot (35), and U-shaped stirring leaf (36) and cavity pivot (35) welded connection, install two reinforcing bar (37) between U-shaped stirring leaf (36) and well idle running shaft (35), and the both ends of reinforcing bar (37) respectively with U-shaped stirring leaf (36) and well idle running shaft (35) welded connection.

3. The crude heparin sodium precipitation apparatus according to claim 2, wherein: one end of cavity pivot (35) runs through teeter chamber (7) and extends to the outside of gear drive room (13), and installs water supply connector (14), install driven gear (45) on the outer wall of cavity pivot (35) upper end, and driven gear (45) set up the inside at gear drive room (13), one side of driven gear (45) is provided with driving gear (46), and driven gear (45) are connected with driving gear (46) meshing, install asynchronous motor (15) on the outer wall of gear drive room (13), the output of asynchronous motor (15) runs through and extends to the inside of gear drive room (13), and is connected with driving gear (46) transmission.

4. The crude heparin sodium precipitation apparatus according to claim 2, wherein: wash dish (38) is installed to the lower extreme of cavity pivot (35), the upper surface and the lower surface of wasing dish (38) all are provided with arc lid (39), upper surface be provided with heat preservation (50) on the outer wall of arc lid (39), be provided with heat preservation inside lining (34) on the inner wall of teeter chamber (7), the outer wall of wasing dish (38) is provided with six contrary nozzles (40) all around.

5. The crude heparin sodium precipitation apparatus according to claim 1, wherein: the liquid inlet (24) is installed to the top of pressing from both sides cover (21) one side outer wall, press from both sides the below of cover (21) opposite side outer wall and install back liquid mouth (25), the inside of pressing from both sides cover (21) is provided with refrigeration chamber (30), the internally mounted of refrigeration chamber (30) has annular radiating fin (31), and annular radiating fin (31) and the outer wall welded connection of drip chamber (10).

6. The crude heparin sodium precipitation apparatus according to claim 1, wherein: a PH value sensor (26) is installed on one side of the upper end of the settling chamber (10), and one end of the PH value sensor (26) penetrates through and extends into the settling chamber (10).

7. The crude heparin sodium precipitation apparatus according to claim 1, wherein: the heat extraction mechanism is characterized in that an electric motor (41) is arranged inside the heat extraction mechanism (19), five exhaust fan blades (42) are arranged at the output end of the electric motor (41), a gauze (43) is arranged at the upper end of the heat extraction mechanism (19), and a metal mesh (44) is arranged on the outer wall of the gauze (43).

8. The crude heparin sodium precipitation apparatus according to claim 1, wherein: the internally mounted of heating conduction board (32) has electric heating wire (33), the externally mounted of hot plate support (12) has and connects electrical ring (28), connect and install power supply connector (29) on the outer wall of electrical ring (28).

9. The crude heparin sodium precipitation apparatus according to claim 1, wherein: upper strata liquid suction valve (27) are installed to the front end of drip chamber (10) top, material level observation window (22) are installed to the front end of drip chamber (10), one side of material level observation window (22) is provided with liquid level line (23).

10. The crude heparin sodium precipitation apparatus according to claim 1, wherein: bearing (9), one side are installed with the junction of first frame (2) and second frame (3) in transmission shaft (8) run through first frame (2) and extend to the inside of belt safety cover (5), and install from driving wheel (48), the below from driving wheel (48) is provided with action wheel (47), action wheel (47) are connected with driving wheel (48) transmission from rubber tape (49) through rubber tape (49), install step motor (6) on the outer wall of belt safety cover (5), and the output of step motor (6) runs through and extends to the inside of belt safety cover (5), and is connected with action wheel (47) transmission.