CN113908088A

CN113908088A - Liquid shampoo

Info

Publication number: CN113908088A
Application number: CN202111032668.0A
Authority: CN
Inventors: 孟宏; 刘有停; 曲召辉; 刘宇红; 刘月恒
Original assignee: Taihe Kangmei Beijing Research Institute of Traditional Chinese Medicine Co Ltd
Current assignee: Taihe Kangmei Beijing Research Institute of Traditional Chinese Medicine Co Ltd
Priority date: 2021-09-03
Filing date: 2021-09-03
Publication date: 2022-01-11

Abstract

The invention relates to shampoo, and belongs to the field of daily chemicals. The shampoo of the invention comprises a surfactant, silicone oil, an anti-irritant composition comprising peach gum extract and optionally cactus extract, a chelating agent and water. Experiments prove that the shampoo disclosed by the invention can effectively reduce irritation, maintain good cleaning power and skin feeling stability, improve smooth hair feeling, relieve the problems of dry and itchy scalp and hair roughness after washing, and has a wide application prospect.

Description

Liquid shampoo

Technical Field

The invention relates to a shampoo with low irritation, and belongs to the field of daily chemicals.

Background

The shampoo is a basic care cosmetic applied to hair and scalp, and the main component of the shampoo is a surfactant. The surfactant provides excellent detergency and foamability for the shampoo, but when the addition amount of the surfactant is too high, dry hair and itching of scalp can occur after washing, and then the problems of scurf, hair roughness and the like are caused.

In order to solve the problems, the existing shampoo in the market mostly adopts the mode of adding milder surfactant or adding fat-endowing agent and humectant to reduce the stimulation of the surfactant, but even if the milder surfactant, fat-endowing agent or humectant is added, the problems of dry and itchy scalp, hair roughness and the like caused by the stimulation of the surfactant still exist. On the other hand, a material having an effect of antagonizing the stimulation by the surfactant may be added to reduce the stimulation, but there are problems of high addition amount, poor targeting, insignificant effect, and the like. Therefore, the development of a shampoo with low irritation is always the focus of attention of technicians.

Disclosure of Invention

Based on the prior art and product defects, the invention aims to provide the shampoo with low irritation, which can protect the scalp and the hairline, effectively reduce the irritation of the surfactant and relieve the problems of dry and itchy scalp and hairline.

In order to achieve the purpose, the invention adopts the following technical scheme:

in a first aspect, the present invention provides a low-irritation shampoo comprising a surfactant, a silicone oil/silicone emulsion, an anti-irritation composition, a chelating agent and water, wherein the anti-irritation composition comprises peach gum extract and optionally, radix clematidis extract.

According to the invention, by "optionally" it is meant that the anti-irritant composition comprises peach gum extract, with or without cactus extract.

According to some embodiments of the invention, the peach gum extract comprises more than 30% by mass of peach gum polysaccharides.

According to a preferred embodiment of the present invention, the peach gum extract contains more than 50% by mass of peach gum polysaccharide.

According to a preferred embodiment of the present invention, the peach gum extract contains more than 70% by mass of peach gum polysaccharide.

According to some embodiments of the invention, the peach gum polysaccharide has an average molecular weight of 100-500 wDa.

According to a preferred embodiment of the invention, the average molecular weight of the peach gum polysaccharide is 200-300 wDa.

According to a preferred embodiment of the present invention, the average molecular weight of the peach gum polysaccharide is 240-280 wDa.

According to some embodiments of the invention, the surfactant comprises an anionic surfactant.

According to some embodiments of the invention, the surfactant comprises an amphoteric surfactant.

According to some embodiments of the invention, the surfactant comprises a nonionic surfactant.

According to some embodiments of the invention, the anionic surfactant comprises one or more of sodium laureth sulfate, ammonium laureth sulfate or TEA laureth sulfate.

According to some embodiments of the invention, the amphoteric surfactant is cocamidopropyl betaine.

According to some embodiments of the invention, the nonionic surfactant is one or both of cocamide MEA, cocamide DEA.

According to some embodiments of the invention, the anti-irritant composition comprises component 1) a peach gum extract and component 2) a cactus extract.

According to some embodiments of the present invention, when the anti-irritant composition comprises component 1) the peach gum extract and component 2) the cactus extract, the average molecular weight of the peach gum polysaccharides and cactus polysaccharides contained in the composition is 100-500 wDa.

According to a preferred embodiment of the present invention, when the anti-irritant composition comprises component 1) the peach gum extract and component 2) the cactus extract, the peach gum polysaccharides and cactus polysaccharides contained in the composition have an average molecular weight of 200-300 wDa.

According to a preferred embodiment of the present invention, when the anti-irritant composition comprises component 1) the peach gum extract and component 2) the cactus extract, the average molecular weight of the peach gum polysaccharides and cactus polysaccharides contained in the composition is 240-280 wDa.

According to some embodiments of the invention, the anti-irritant composition further comprises as component 3) one or more of dextrin, cyclodextrin, methyl cyclodextrin, hydroxypropyl cyclodextrin, trehalose, polyvinylpyrrolidone, methyl cellulose, methylhydroxyethyl cellulose, hydroxypropylmethyl cellulose, hydroxyethyl cellulose and hydroxypropyl cellulose.

According to some preferred embodiments of the present invention, the anti-irritant composition is prepared by a process comprising the steps of:

(1) extracting peach gum and optional radix Clematidis with water to obtain primary extractive solution;

(2) and centrifuging the primary extract to obtain a supernatant.

According to some embodiments of the present invention, the extraction temperature in step (1) is 50-90 ℃, for example, 50 ℃, 51 ℃, 52 ℃, 53 ℃, 54 ℃, 55 ℃, 56 ℃, 57 ℃, 58 ℃, 59 ℃, 60 ℃, 61 ℃, 62 ℃, 65 ℃, 68 ℃, 69 ℃, 70 ℃, 75 ℃, 78 ℃, 80 ℃, 82 ℃, 84 ℃, 88 ℃, 90 ℃, and the values between these values.

According to a preferred embodiment of the present invention, in the step (1), the extraction temperature is 60 to 75 ℃, and may be, for example, 60 ℃, 61 ℃, 62 ℃, 65 ℃, 68 ℃, 69 ℃, 70 ℃, 75 ℃.

According to some embodiments of the invention, in the step (1), the extraction time is 0.5-5h, for example, 30min, 40min, 50min, 1h, 1.5h, 2h, 2.5h, 3h, 3.5h, 4h, 5h, and the values between these values.

According to some embodiments of the invention, the weight ratio of peach gum to cactus in the anti-irritant composition is 1: 5-15: 1.

according to some preferred embodiments of the invention, the weight ratio of peach gum to cactus in the anti-irritant composition is 1: 10-10: 1.

according to some embodiments of the invention, the weight ratio of the total weight of peach gum and cactus to water in step (1) is 1: 10-1: 50, for example, may be 1: 10(m/m), 1: 11(m/m), 1: 12(m/m), 1: 13(m/m), 1: 14 (m/m), 1: 15(m/m), 1: 16(m/m), 1: 17(m/m), 1: 18(m/m), 1: 20(m/m), 1: 25(m/m), 1: 27(m/m), 1: 30(m/m), 1: 32(m/m), 1: 35(m/m), 1: 36(m/m), 1: 39(m/m), 1: 40(m/m), 1: 41(m/m), 1: 42(m/m), 1: 45(m/m), 1: 48(m/m), 1: 50 (m/m).

According to a preferred embodiment of the present invention, in the step (1), the weight ratio of the total weight of the peach gum and the cactus to the water is 1: 20-1: 40, for example, may be 1: 20(m/m), 1: 25(m/m), 1: 27(m/m), 1: 30(m/m), 1: 32(m/m), 1: 35(m/m), 1: 36(m/m), 1: 39(m/m), 1: 40 (m/m).

According to some embodiments of the present invention, the centrifugation in the step (2) is 4000-8000rpm for 5-30 min.

According to some embodiments of the invention, the method of preparing the anti-irritant composition further comprises step (3): and (3) carrying out microfiltration on the supernatant obtained in the step (2) by adopting a microfiltration membrane component to obtain a micro-filtrate.

According to some embodiments of the invention, the microfiltration membrane module of step (3) is selected from a ceramic microfiltration membrane module or a roll-type microfiltration membrane module.

According to some embodiments of the invention, the pore size of the microfiltration membrane module is between 50 and 200 nm.

According to some embodiments of the invention, the pore size of the microfiltration membrane module is 100 nm.

According to some embodiments of the invention, the method of preparing the anti-irritant composition further comprises step (4): and (4) compounding the micro-filtrate obtained in the step (3) with one or more of dextrin, cyclodextrin, methyl cyclodextrin, hydroxypropyl cyclodextrin, trehalose, polyvinylpyrrolidone, methyl cellulose, methyl hydroxyethyl cellulose, hydroxypropyl methyl cellulose, hydroxyethyl cellulose or hydroxypropyl cellulose to obtain a compound.

According to some embodiments of the invention, the weight ratio of the micro filtrate to one or more of dextrin, cyclodextrin, methyl cyclodextrin, hydroxypropyl cyclodextrin, trehalose, polyvinylpyrrolidone, methyl cellulose, methyl hydroxyethyl cellulose, hydroxypropyl methyl cellulose, hydroxyethyl cellulose or hydroxypropyl cellulose is 1: 1-1: 20.

according to a preferred embodiment of the present invention, the weight ratio of the micro-filtrate to one or more of dextrin, cyclodextrin, methyl cyclodextrin, hydroxypropyl cyclodextrin, trehalose, polyvinylpyrrolidone, methyl cellulose, methyl hydroxyethyl cellulose, hydroxypropyl methyl cellulose, hydroxyethyl cellulose or hydroxypropyl cellulose is 1: 5-1: 15.

according to some embodiments of the present invention, the compound obtained in step (4) may be dried and sterilized before use.

According to some embodiments of the invention, the drying is freeze-drying at-80 ℃ to-50 ℃ for 8 to 32 h.

According to some embodiments of the invention, the drying is spray drying, the inlet air temperature is 100 ℃ and 170 ℃, and the material flow rate is controlled to be 5-50 mL/min.

According to some embodiments of the invention, the drying is oven drying at 90-150 ℃ for 12-50h, pulverizing and sieving with a 80 mesh sieve, and taking the undersize fraction.

According to some embodiments of the invention, the sterilization process is cobalt 60 sterilization for 1-8 h.

According to some embodiments of the present invention, the sterilization is performed by using 100-700W microwave for 0.5-30 min.

According to some embodiments of the invention, the sterilization is dry heat sterilization at 90-150 ℃ for 0.5-5 h.

According to some embodiments of the invention, the shampoo further comprises one or more of a pearlescent agent, a cationic conditioning agent, ammonium xylene sulfonate, a pH adjuster, sodium chloride, a preservative, and a fragrance.

According to some embodiments of the present invention, the shampoo comprises the following raw materials in parts by weight, based on the total weight of the shampoo: 5.00 to 30.00 weight percent of anionic surfactant, 0.00 to 20.00 weight percent of amphoteric surfactant, 0.30 to 5.00 weight percent of nonionic surfactant, 0.00 to 3.00 weight percent of pearling agent, 0.30 to 5.00 weight percent of silicone oil/emulsified silicone oil, 0.00 to 1.00 weight percent of cation conditioner, 0.01 to 5.00 weight percent of anti-irritation composition, 0.00 to 1.50 weight percent of ammonium xylene sulfonate, 0.00 to 2.00 weight percent of pH regulator, 0.05 to 1.00 weight percent of chelating agent, 0.00 to 2.00 weight percent of sodium chloride, 0.05 to 1.00 weight percent of preservative and 0.00 to 1.00 weight percent of essence.

According to a further embodiment of the invention, the shampoo comprises the following raw materials in parts by weight based on the total weight of the shampoo: 10.00-20.00 wt% of anionic surfactant, 0.01-15.00 wt% of amphoteric surfactant, 0.35-4.50 wt% of nonionic surfactant, 0.00-2.00 wt% of pearling agent, 0.50-3.00 wt% of silicone oil/emulsified silicone oil, 0.00-0.50 wt% of cation conditioner, 0.01-4.00 wt% of anti-irritation composition, 0.01-1.00 wt% of ammonium xylene sulfonate, 0.00-2.00 wt% of pH regulator, 0.15-0.80 wt% of chelating agent, 0.00-1.50 wt% of sodium chloride, 0.05-1.00 wt% of preservative and 0.00-1.00 wt% of essence.

According to some embodiments of the invention, the pearlescent agent is ethylene glycol distearate.

According to some embodiments of the invention, the silicone oil/silicone emulsion comprises one or more of polydimethylsiloxane, dimethiconol, or amodimethicone.

According to some embodiments of the invention, the cationic conditioning agent comprises polyquaternium-7, polyquaternium-10, and the like.

According to some embodiments of the invention, the pH adjusting agent is a pH adjusting agent conventional in the art, and may be, for example, citric acid, sodium citrate, and the like.

According to some embodiments of the invention, the chelating agent is a chelating agent conventional in the art, and may be, for example, disodium EDTA, trisodium EDTA, tetrasodium EDTA.

The preservatives described herein are conventional in the art.

The essence of the invention is the conventional essence in the field.

The invention has the beneficial effects that:

the anti-irritation composition is added into the shampoo, and consists of the peach gum extract and the optional cactus extract. The shampoo disclosed by the invention is low in irritation, can reduce the dry and itching feeling of the scalp after washing while keeping good cleaning power, and is smooth in hairline.

The specific implementation mode is as follows:

in order that the invention may be more readily understood, reference will now be made in detail to the following examples. It will be understood by those skilled in the art that the embodiments of the present invention are illustrative only and not limiting of the invention. The specific experimental methods which are not mentioned in the examples of the invention are all conventional methods in the field. The reagents or apparatus used are conventional products commercially available from normal sources, not indicated by the manufacturer.

TABLE 1 raw materials and suppliers

TABLE 2 Instrument information List

Example 1 shampoo composition and formulation

Example 2 shampoo composition and formulation

Example 3 shampoo composition and formulation

Example 4 shampoo composition and formulation

Example 5 shampoo composition and formulation

Example 6 shampoo composition and formulation

Example 7 shampoo composition and formulation

Example 8 shampoo composition and formulation

The anti-irritation composition is prepared by the following steps:

anti-irritant composition a: adding 50 parts of pure water into 1 part of peach gum and 1 part of cactus, extracting with pure water, and extracting for 2 hours at 80 ℃; centrifuging at 5000rpm/min for 20min, and collecting supernatant; performing microfiltration and concentration by using a 100nm microfiltration membrane component, removing substances with the molecular weight below 100wDa in the supernatant, and retaining the effluent liquid to obtain a microfiltration solution; according to the micro-filtrate: hydroxypropyl cyclodextrin ═ 1: 5(m/m) compounding; freeze-drying the compounded substance at-80 deg.C for 12 h; pulverizing, sieving with 80 mesh sieve, and collecting the sieved part; sterilizing with cobalt 60 for 3 hr to obtain anti-irritation composition A.

In the anti-irritation composition A, the average molecular weight of the peach gum polysaccharide is 100-500 wDa.

Anti-irritant composition B: adding 50 parts of pure water into 1 part of peach gum and 1 part of cactus, extracting with pure water, and extracting for 2 hours at 80 ℃; centrifuging at 5000rpm/min for 20min, and collecting supernatant; performing microfiltration and concentration by using a 100nm microfiltration membrane component, removing substances with the molecular weight below 100wDa in the supernatant, and retaining the effluent liquid to obtain a microfiltration solution; according to the micro-filtrate: hydroxypropyl cyclodextrin ═ 1: 10(m/m) compounding; freeze-drying the compounded substance at-80 deg.C for 12 h; pulverizing, sieving with 80 mesh sieve, and collecting the sieved part; sterilizing with cobalt 60 for 3 hr to obtain anti-irritation composition B.

In the anti-irritation composition B, the average molecular weight of the peach gum polysaccharide is 100-500 wDa.

The preparation process of the shampoo comprises the following steps:

(1) heating phase A to 80-85 deg.C, stirring to dissolve completely;

(2) keeping the temperature at 80-85 deg.C, adding the B phase raw material, stirring to dissolve completely, and stirring for 10 min;

(3) stirring at low speed, cooling to 45-50 deg.C, and adding C phase raw materials;

(4) adding the raw materials of the phase D, keeping the temperature and stirring at a low speed for 10min until the raw materials are completely dissolved;

(5) cooling to below 40 ℃, and adding the E-phase raw material to adjust the consistency;

(6) adding the phase F, and uniformly stirring;

(7) stirring and cooling, cooling to below 38 ℃, filtering and discharging.

The formula of other samples of the invention is shown as follows:

off-line state observation and skin feel stability test:

after the shampoo is manufactured, off-line state observation is carried out, and then the using performance of the shampoo is tested. And observing whether the offline product has unstable phenomena such as layering, precipitation, over-thin and over-thick phenomena or not, and if not, the state is acceptable. And (4) taking a proper amount of shampoo for testing, and observing the foaming power, the cleaning power, the scalp and hair state after washing.

The results of the line status observation and skin feel stability tests for example 1 and samples 1-5 are as follows:

the results of the off-line state observation and the skin feel stability test show that:

the hair conditioner of example 1 of the invention has good off-line state, good foamability, good cleaning power, no discomfort of scalp after washing, smooth hair and relief of hair roughness. The same experiments with shampoo samples prepared in other examples were carried out by the inventors, leading to the same conclusions.

First, reduce the irritation experiment

And (3) testing a sample: example 1 shampoo, sample 1 shampoo, some commercial repair water nourishing shampoo (main ingredients are water, sodium laureth sulfate, sodium chloride, polydimethylsiloxane, ethylene glycol distearate, cocamidopropyl betaine, sodium xylene sulfonate, citric acid, methylchloroisothiazolinone, etc.).

(1) Erythrocyte assay

Experimental methods

The density of erythrocytes in the erythrocyte suspension is adjusted at room temperature, and the OD value of erythrocytes is 1.3000-1.7000 when the erythrocytes are fully hemolyzed at 530 nm. 0.10% is selected as the detection concentration, and the hemolysis rate of the corresponding red blood cells is between 60% and 90% when 0.10% of the product solution of the sample 1 is used.

Taking a centrifugal tube, sequentially adding a test object, PBS and RBC suspension according to the table 3, and uniformly mixing, wherein the final concentration of a sample system is the test concentration; placing in a shaking table, incubating for 10min, and centrifuging; observing the phenomenon, taking supernatant, and determining OD 530; the hemolysis rate was calculated.

TABLE 3 reaction system (μ L)

Addition of reagents	Test sample	PBS	RBC suspensions
				Sample set	40	260	100
Model control group	300	0	100
				Solvent control group	0	300	100

The hemolysis rate is calculated as:

the erythrocyte hemolysis rate (%) (OD _ sample-OD _ solvent control)/(OD _ model control-OD _ solvent control) × 100.

TABLE 4 influence of the samples on the haemolysis Rate of erythrocytes

Sample name	Sample 1	Market contest	Example 1	PBS
					Hemolytic rate of erythrocyte%	71	45	16	0

As can be seen from Table 4, the hemolysis rate of erythrocytes was significantly reduced when the 0.10% solution of example 1 was used for the hemolysis test. Experiments prove that the shampoo disclosed by the invention can effectively reduce irritation.

(2) Chick embryo test

Experimental methods

The eggs of the SPF-grade white Lai Hangzhou chicken are fertilized and are fresh, clean and intact, and the mass of the eggs is 50g-60 g. Setting the incubation temperature to be 37.5 +/-0.5 ℃, the relative humidity to be 55-70%, the turntable frequency to be 3-6 times/h, turning over the eggs and incubating for 3 days, and stopping turning over the eggs after windowing on the 4 th day. When the eggs are incubated for 4 days, the eggs should be checked, unfertilized chick embryos are discarded, and broken or thin-shelled chick embryos cannot be used.

After the chick embryos are incubated for 4 days, the small end of the egg is punched with an electric grinder, 2-3mL of egg white is extracted with a 10mL syringe, a small window of 1cm by 1cm is made in the middle of the egg slightly near the large end using the electric grinder to expose the chorioallantoic membrane (CAM) of the chick embryos, and the eggshell and eggshell membrane are carefully removed with forceps. The structure of the vascular system and the growth of the chick embryos should be observed at this time. Sealing the hole at the small end and the small window at the middle part with transparent adhesive tape, and placing the sealed small window into an incubator for continuous culture. The growth condition of the chick embryos needs to be checked every day, and dead embryos are discarded in time. 10 day old chick embryos were used for the experiment. The transparent adhesive tape for sealing the small window is torn off, the area of the small window is enlarged by using tweezers, the observation visual field is enlarged, and the operation is careful without damaging the integrity of the egg membrane. The structure of the vascular system should be observed again at this point and a decision made as to its integrity and suitability for testing. The teflon ring was placed on the CAM to prepare for sample addition.

Each test subject was used as a group, and 6 chick embryos were tested in each group, and 40. mu.l of the test subject was applied directly to the surface of the CAM in the Teflon ring. After 30min at 37 ℃, the change of chorioallantoic membrane toxicity effect indexes (such as bleeding, angiolysis, coagulation and the like) is observed, and the Endpoint Score (ES) is calculated in a combined manner. And comparing the endpoint scores of the test object treatment groups with the endpoint scores of the negative control, wherein the lower the endpoint score of the sample is, the stronger the anti-stimulation effect of the test object is prompted.

TABLE 5 Effect of samples on chick embryo chorioallantoic Membrane stimulation fraction

Sample name	3% sample 1	3% of the commercial competitive products	3% example 1	Physiological saline
					Chick embryo stimulation fraction (ES)	22.0	18.5	12.5	0

As can be seen from Table 5, the use of the shampoo of example 1 reduced the irritation of the chick embryo chorioallantoic membrane. Experiments prove that the shampoo disclosed by the invention can effectively reduce irritation.

Secondly, the problems of dry and itchy scalp and hair roughness are relieved

60 volunteers were selected and divided into 3 groups of 20 individuals and tested using sample 1, example 1 and a commercial auction, respectively. Wetting hair and scalp by using clear water, applying a proper amount of a tested product to the palm of the hand, slightly kneading the product to obtain foam, spreading the foam on the hair, and slightly kneading the scalp for 3min by using a tester; then rinsed clean with clear water and used for 1 week each sample. The tester scores according to the use effect of the tester. The scoring criteria were in 10 points, the scoring criteria are shown in table 6, and the average results are shown in table 7.

TABLE 6 evaluation criteria

	Weak (weak)	Is weaker	Medium and high grade	Is stronger	High strength
						Cleaning power	0.00-2.00	2.00-4.00	4.00-6.00	6.00-8.00	8.00-10.00
Dry and itchy scalp after washing	0.00-2.00	2.00-4.00	4.00-6.00	6.00-8.00	8.00-10.00
						Smooth hair feeling after washing	0.00-2.00	2.00-4.00	4.00-6.00	6.00-8.00	8.00-10.00
Coarse hair feeling after washing	0.00-2.00	2.00-4.00	4.00-6.00	6.00-8.00	8.00-10.00

The cleaning power investigation index in the evaluation is the foaming property and the washing feeling of the tested shampoo after the test shampoo is used by the test subject.

The dry scalp itch after washing in the evaluation means the degree of scalp itch after a subject washes hair with the test shampoo.

The smooth feeling of hair after washing in this evaluation means the combing property of wet hair and dry hair after the subject has washed hair with the test shampoo.

The hair roughness after washing in this evaluation means whether the subject has dried hair with roughness after shampooing with the test shampoo.

TABLE 7 evaluation of after-wash feeling of test products

	Sample 1	Example 1	Market contest
				Cleaning power	9.05	9.00	9.00
Dry and itchy scalp after washing	8.95	6.00	7.60
				Smooth hair feeling after washing	5.85	8.75	7.30
Coarse hair feeling after washing	9.00	5.80	7.45

As can be seen from Table 7, the shampoo of example 1 can reduce the dry and scratchy feeling of the scalp after washing and smooth the hair while maintaining good cleaning power. Experiments prove that the shampoo disclosed by the invention can relieve the problems of dry and itchy scalp and rough hair after washing and smooth hair.

In conclusion, the shampoo disclosed by the invention maintains good cleaning power and skin feeling stability while reducing irritation, improves smooth hair feeling, and relieves the problems of dry and itchy scalp and rough hair after washing.

Claims

1. A shampoo comprises a surfactant, a silicone oil/silicone emulsion, an anti-irritant composition comprising component 1) a peach gum extract and optionally component 2) a cactus extract, a chelating agent and water.

2. The shampoo as claimed in claim 1 wherein the average polysaccharide molecular weight of the peach gum polysaccharide in the peach gum extract is 100-500wDa, preferably 200-300wDa, more preferably 240-280 wDa.

3. The shampoo according to claim 2, wherein the peach gum extract comprises more than 30% peach gum polysaccharide, preferably more than 50% peach gum polysaccharide, and more preferably more than 70% peach gum polysaccharide.

4. Shampoo according to any of claims 1 to 3 characterised in that the surfactant comprises an anionic surfactant, and/or an amphoteric surfactant, and/or a nonionic surfactant; preferably, the anionic surfactant comprises one or more of sodium laureth sulfate, ammonium laureth sulfate or TEA salt of laureth sulfate, and/or the amphoteric surfactant is cocamidopropyl betaine, and/or the nonionic surfactant is one or both of cocamide MEA and cocamide DEA.

5. The shampoo according to any of claims 1 to 4, characterized in that the anti-irritant composition comprises 1) a peach gum extract and component 2) a cactus extract, preferably the peach gum polysaccharide and the cactus polysaccharide contained in the anti-irritant composition have an average polysaccharide molecular weight of 100-500wDa, preferably 200-300wDa, more preferably 240-280 wDa.

6. Shampoo according to any of claims 1 to 5 characterised in that the anti-irritant composition further comprises as component 3) one or more of dextrin, cyclodextrin, methylcyclodextrin, hydroxypropyl cyclodextrin, trehalose, polyvinylpyrrolidone, methylcellulose, methylhydroxyethylcellulose, hydroxypropylmethylcellulose, hydroxyethylcellulose and hydroxypropylcellulose.

7. Shampoo according to any of claims 1 to 6, characterised in that the anti-irritant composition is prepared by a process comprising the following steps:

(1) extracting peach gum and optional radix Clematidis with water to obtain primary extractive solution, preferably at 50-90 deg.C for 0.5-5 hr;

(2) and centrifuging the primary extract to obtain a supernatant.

8. The shampoo as claimed in claim 7 wherein in step (1), the weight ratio of peach gum to cactus is 1: 5-15: 1, preferably 1: 10-10: 1.

9. the shampoo according to claim 7 or 8, wherein the weight ratio of the total weight of peach gum and cactus to water in step (1) is 1: 10-1: 50.

10. the shampoo according to any of claims 7 to 9, wherein the method for preparing the anti-irritant composition further comprises step (3): and (3) carrying out microfiltration on the supernatant obtained in the step (2) by adopting a microfiltration membrane module to obtain a micro-filtrate, preferably, the microfiltration membrane module is selected from one or more of a ceramic microfiltration membrane module and a roll-type microfiltration membrane module, more preferably, the pore diameter of the microfiltration membrane module is 50-200nm, and more preferably 100 nm.

11. The shampoo according to claim 10, wherein the method for preparing the anti-irritant composition further comprises step (4): compounding the micro-filtrate obtained in the step (3) with one or more of dextrin, cyclodextrin, methyl cyclodextrin, hydroxypropyl cyclodextrin, trehalose, polyvinylpyrrolidone, methyl cellulose, methyl hydroxyethyl cellulose, hydroxypropyl methyl cellulose, hydroxyethyl cellulose or hydroxypropyl cellulose to obtain a compound; preferably, the weight ratio of the micro-filtrate to one or more of dextrin, cyclodextrin, methyl cyclodextrin, hydroxypropyl cyclodextrin, trehalose, polyvinylpyrrolidone, methyl cellulose, methyl hydroxyethyl cellulose, hydroxypropyl methyl cellulose, hydroxyethyl cellulose or hydroxypropyl cellulose is 1: 1-1: 20, preferably 1: 5-1: 15.

12. the shampoo according to any one of claims 1-11, further comprising one or more of a pearlescent agent, a cationic conditioning agent, ammonium xylene sulfonate, a pH adjuster, sodium chloride, a preservative and a fragrance; preferably, the shampoo comprises the following raw materials in parts by weight based on the total weight of the shampoo: 5.00 to 30.00 weight percent of anionic surfactant, 0.00 to 20.00 weight percent of amphoteric surfactant, 0.30 to 5.00 weight percent of nonionic surfactant, 0.00 to 3.00 weight percent of pearling agent, 0.30 to 5.00 weight percent of silicone oil/emulsified silicone oil, 0.00 to 1.00 weight percent of cation conditioner, 0.01 to 5.00 weight percent of anti-irritation composition, 0.00 to 1.50 weight percent of ammonium xylene sulfonate, 0.00 to 2.00 weight percent of pH regulator, 0.05 to 1.00 weight percent of chelating agent, 0.00 to 2.00 weight percent of sodium chloride, 0.05 to 1.00 weight percent of preservative and 0.00 to 1.00 weight percent of essence.