CN113889276A - Data processing device, system and kit for auxiliary evaluation of arteriosclerosis - Google Patents
Data processing device, system and kit for auxiliary evaluation of arteriosclerosis Download PDFInfo
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Abstract
The invention discloses a data processing device, a system and a kit for auxiliary evaluation of arteriosclerosis. The data processing device comprises the following modules: the data receiving module receives sex, age, systolic pressure, heart rate, abdominal circumference, body mass index and estimated system vascular resistance data of a person to be measured; the data operation module receives the data of the data receiving module and calculates the numerical value of the carotid artery-femoral artery pulse wave conduction velocity cf-PWV according to the following formula; cf-PWV-3.789 +0.278 × gender +0.075 × age +0.055 × systolic blood pressure +0.024 × heart rate +1.280 × abdominal circumference/body mass index-0.003 × estimated systemic vascular resistance; the data storage module stores the judgment threshold value; the data comparison module receives the cf-PWV and judges that the threshold value is compared with the cf-PWV; the judgment module receives the comparison result, judges the comparison result according to a preset judgment condition, judges the person to be tested meeting the preset judgment condition to be the arteriosclerosis patient or the candidate of the person to be tested to be the arteriosclerosis patient, otherwise, judges the person to be tested not to be the arteriosclerosis patient or the candidate of the person to be tested not to be the arteriosclerosis patient, and outputs the judgment result. The invention has simple and convenient use and accurate result.
Description
Technical Field
The invention relates to a data processing device, a system and a kit for auxiliary evaluation of arteriosclerosis, and belongs to the field of biomedicine.
Background
Cardiovascular and cerebrovascular diseases are the leading causes of death of urban and rural residents in China, and arteriosclerosis is the important pathological basis and the main risk factor of the death. The development and progression of arteriosclerotic lesions is a hidden, progressive process, functional lesions appear before angiogenic structural lesions, clinically asymptomatic, and manifest as an increase in arterial stiffness. The change of arterial stiffness is the main manifestation of artery wall degeneration, and with the increase of arterial stiffness, the blood pressure components are changed, so that the systolic pressure is increased, the diastolic pressure is reduced, and the pulse pressure is increased, which are independent risk factors of various cardiovascular and cerebrovascular diseases and death. Aging is a major cause of the degeneration of the arterial wall, and chronic diseases such as hypertension can accelerate and aggravate the degeneration process. The method has the advantages that the propagation speed of the pulse wave of the wall of the aorta is increased due to the breakage of elastic fibers and the increase of collagen fibers in the reconstruction process of the wall of the aorta, the stiffness change of the elastic aorta can be reflected by measuring the pulse wave propagation speed of carotid artery and femoral artery, the influence of vasoactive substances in blood is small, the result repeatability is good, and the method is a gold index for evaluating the stiffness of the aorta accepted and recommended by hypertension guidelines at home and abroad at present. However, the conventional arterial elasticity measuring device is used as a medical instrument in a medical place, and is not suitable for daily detection of families or individuals due to large volume, high price and relatively complex operation, so that the conventional arterial elasticity measuring device has difficulty in long-term monitoring of chronic diseases and detection of non-disease people.
With the deep understanding of the health of the Chinese people, the demand of the public on professional health, sub-health and disease assessment means is increased, and a convenient, practical and professional assessment method is provided for the Chinese people, so that the method has important significance in guiding the people to correctly know the body state and the disease assessment. The blood vessel function and structural lesion are direct windows of cardiovascular and cerebrovascular diseases, the research group detects clinical indexes and blood vessel elasticity functions of the whole population including healthy population, normal high-value blood pressure and hypertension under the support of 863 projects, establishes a simple assessment model of blood vessel elasticity function indexes (SVC, SVR and BAD) suitable for the population in China and obtains the invention patent. The establishment of the evaluation model provides a method for evaluating the early vascular function of the human population.
The method for evaluating the function of the blood vessel is more, and the method adopted in the previous research is pulse wave waveform analysis, so that a plurality of arterial elasticity data such as systemic vascular resistance and the like can be obtained. With the development of methodology, carotid-femoral pulse wave velocity (cf-PWV) has become an internationally recognized index of stiffness of arteries, but the detection of the method has high requirements on technicians and long time consumption, so that the popularization and application of the method are difficult. Therefore, there is a need for an accurate and easy estimation model for arterial function assessment.
Disclosure of Invention
The invention aims to provide a data processing device, a system and a kit for assisting in evaluating arteriosclerosis.
The invention provides a data processing device for assisting in evaluating arteriosclerosis, which comprises the following modules:
(1) a data receiving module; the data receiving module is configured to receive gender, age, systolic blood pressure, heart rate, abdominal circumference, body mass index, estimated systemic vascular resistance data of the person under test;
(B) a data operation module; the data operation module is configured to receive the data from the data receiving module and is configured to calculate a value of the carotid-femoral pulse wave velocity according to the following formula I according to the gender, the age, the systolic blood pressure, the heart rate, the abdominal circumference, the body mass index and the estimated systemic vascular resistance value;
formula I: cf-PWV-3.789 +0.278 × gender +0.075 × age +0.055 × systolic blood pressure +0.024 × heart rate +1.280 × abdominal circumference/body mass index-0.003 × estimated systemic vascular resistance;
in the formula I, cf-PWV represents the carotid-femoral pulse wave conduction velocity; when the person to be tested represents a male, the sex value is 1; when the person to be tested represents a woman, the sex value is 0; abdominal circumference is in centimeters, and weight index is weight/height2The unit: kilogram/meter2(ii) a Age in units of years; the units of systolic pressure and diastolic pressure are mmHg; heart rate in units of beats/minute;
(3) a data storage module; the data storage module is configured to store a decision threshold;
(4) a data comparison module; the data comparison module is configured to receive the carotid-femoral pulse wave velocity value sent by the operation module and call the judgment threshold value from the data storage module to compare with the carotid-femoral pulse wave velocity value;
(5) a judgment module; the judging module is configured to receive the comparison result sent by the data comparing module, judge the comparison result according to a preset judging condition, judge the person to be tested who meets the preset judging condition as an arteriosclerosis patient or a candidate of the person to be tested who does not meet the preset judging condition as the arteriosclerosis patient, judge the person to be tested who does not meet the preset judging condition as the arteriosclerosis patient or the candidate of the person to be tested who does not meet the preset judging condition as the arteriosclerosis patient, and output the judgment result.
In the above data processing apparatus, the predetermined determination condition is: if the carotid-femoral pulse wave velocity value is larger than or equal to the judgment threshold, the person to be detected is or is selected as the arteriosclerosis patient; otherwise, the subject is not, or is not a candidate for, an arteriosclerotic patient.
In the above data processing apparatus, the determination threshold stored in the data storage module is 12 m/s.
In the data processing apparatus, in formula i, the estimated systemic vascular resistance is calculated according to formula ii as follows:
formula II: the systemic vascular resistance of the whole population is 1659-55.299 × sex-134.591 × age group (30-44 years) -24.746 × age group (45-54 years) -30.954 × body mass index-7.459 × abdominal circumference/body mass index +6.974 × systolic pressure-3.967 × pulse pressure difference;
in the formula II, when the person to be tested represents a male, the sex value is 1; when the person to be tested represents a woman, the sex value is 0; when the age is 30-44 years, the numerical value of the age group (30-44 years) is 1, and the numerical value of the age group (45-54 years) is 0; when the age is 45-54 years, the numerical value of the age group (45-54 years) is 1, and the numerical value of the age group (30-44 years) is 0; abdominal circumference is in centimeters, and weight index is weight/height2The unit: kilogram/meter2(ii) a Systolic blood pressure is in mmHg; the pulse pressure difference is the value of diastolic pressure minus systolic pressure, and the unit of diastolic pressure is mmHg.
In the above data processing apparatus, the data processing apparatus further includes a control module or a controller; the control module or the controller is used for controlling each module.
The invention also provides an arteriosclerosis auxiliary evaluation system, which comprises a blood pressure meter, a flexible rule, a weight scale, a timing device and a control device;
the control device is configured or programmed to perform the steps of:
receiving sex, age, systolic blood pressure, heart rate, abdominal circumference, body mass index and estimated systemic vascular resistance data of a person to be detected;
calculating a carotid-femoral pulse wave velocity value according to the following formula I according to the gender, the age, the systolic blood pressure, the heart rate, the abdominal circumference, the body mass index and the estimated systemic vascular resistance value;
formula I: cf-PWV-3.789 +0.278 × gender +0.075 × age +0.055 × systolic blood pressure +0.024 × heart rate +1.280 × abdominal circumference/body mass index-0.003 × estimated systemic vascular resistance;
in the formula I, cf-PWV represents the carotid-femoral pulse wave conduction velocity; when the person to be tested represents a male, the sex value is 1; when the person to be tested represents a woman, the sex value is 0; abdominal circumference is in centimeters, and weight index is weight/height2The unit: kilogram/meter2(ii) a Age in units of years; the units of systolic pressure and diastolic pressure are mmHg; heart rate in units of beats/minute;
comparing the carotid-femoral pulse wave velocity value with a judgment threshold value to obtain a comparison result;
and judging the comparison result according to a preset judgment condition, judging that the person to be tested meeting the preset judgment condition is or is not a patient suffering from arteriosclerosis, judging that the person to be tested not meeting the preset judgment condition is or is not a patient suffering from arteriosclerosis, and outputting the judgment result.
The above system further includes:
the system further comprises an input device and an output device;
the input device is configured to input the systolic blood pressure, the heart rate, the abdominal circumference, the body mass index and the estimated systemic vascular resistance data of the subject collected by the sphygmomanometer, a tape, a weight scale, a timing device, respectively;
the output device is configured to output the determination result.
The use method of the system comprises the following steps: obtaining the systolic blood pressure, the heart rate, the abdominal circumference, the estimated systemic vascular resistance data of the subject using (a1) - (a3) as follows; then, the control device in the system is adopted to execute the steps, and a judgment result is output;
(a1) a blood pressure monitor;
(a2) a flexible rule;
(a3) weighing;
(a4) a timing device.
The present invention also provides a computer-readable storage medium storing a computer program for performing the steps of:
receiving sex, age, systolic blood pressure, heart rate, abdominal circumference, body mass index and estimated systemic vascular resistance data of a person to be detected;
calculating a carotid-femoral pulse wave velocity value according to the following formula I according to the gender, the age, the systolic blood pressure, the heart rate, the abdominal circumference, the body mass index and the estimated systemic vascular resistance value;
formula I: cf-PWV-3.789 +0.278 × gender +0.075 × age +0.055 × systolic blood pressure +0.024 × heart rate +1.280 × abdominal circumference/body mass index-0.003 × estimated systemic vascular resistance;
in the formula I, cf-PWV represents the carotid-femoral pulse wave conduction velocity; when the person to be tested represents a male, the sex value is 1; when the person to be tested represents a woman, the sex value is 0; abdominal circumference is in centimeters, and weight index is weight/height2The unit: kilogram/meter2(ii) a Age in units of years; the units of systolic pressure and diastolic pressure are mmHg; heart rate in units of beats/minute;
comparing the carotid-femoral pulse wave velocity value with a judgment threshold value to obtain a comparison result;
and judging the comparison result according to a preset judgment condition, judging that the person to be tested meeting the preset judgment condition is or is not a patient suffering from arteriosclerosis, judging that the person to be tested not meeting the preset judgment condition is or is not a patient suffering from arteriosclerosis, and outputting the judgment result.
The invention further provides a kit for auxiliary evaluation of arteriosclerosis, which comprises a parameter acquisition device and a readability carrier;
the parameter acquisition device comprises a device for acquiring various parameters involved in the readability carrier;
the readability carrier has the following formula I,
formula I: cf-PWV-3.789 +0.278 × gender +0.075 × age +0.055 × systolic blood pressure +0.024 × heart rate +1.280 × abdominal circumference/body mass index-0.003 × estimated systemic vascular resistance;
in the formula I, cf-PWV represents the carotid-femoral pulse wave conduction velocity; when the person to be tested represents a male, the sex value is 1; when the person to be tested represents a woman, the sex value is 0; abdominal circumference is in centimeters, and weight index is weight/height2The unit: kilogram/meter2(ii) a Age in units of years; the units of systolic pressure and diastolic pressure are mmHg; heart rate in units of beats/minute;
if the carotid-femoral pulse wave velocity value is larger than or equal to the judgment threshold, the person to be detected is or is selected as the arteriosclerosis patient; otherwise, the subject is not, or is not a candidate for, an arteriosclerotic patient.
In the above kit, in formula i, the estimated systemic vascular resistance is calculated according to the following formula ii:
formula II: the systemic vascular resistance of the whole population is 1659-55.299 × sex-134.591 × age group (30-44 years) -24.746 × age group (45-54 years) -30.954 × body mass index-7.459 × abdominal circumference/body mass index +6.974 × systolic pressure-3.967 × pulse pressure difference;
in the formula II, when the person to be tested represents a male, the sex value is 1; when the person to be tested represents a woman, the sex value is 0; when the age is 30-44 years, the numerical value of the age group (30-44 years) is 1, and the numerical value of the age group (45-54 years) is 0; when the age is 45-54 years, the numerical value of the age group (45-54 years) is 1, and the numerical value of the age group (30-44 years) is 0; abdominal circumference is in centimeters, and weight index is weight/height2The unit: kilogram/meter2(ii) a Systolic blood pressure is in mmHg; the pulse pressure difference is the value of diastolic pressure minus systolic pressure, and the unit of diastolic pressure is mmHg.
In the kit, the parameter acquisition equipment comprises a blood pressure meter, a flexible rule, a weight scale and a timing device.
In the above kit, the kit further comprises a recording means and/or a calculating means; the recording tool comprises a pen and/or a computer.
In the above kit, the calculation means comprises a calculator and/or the computer.
In the kit, the readable carrier is a kit instruction; the contents of formula I are printed on a card.
In the kit, the readable carrier is a computer readable carrier.
The invention has the following advantages:
the invention adopts the index value which is frequently measured clinically, and the carotid artery-femoral artery pulse wave conduction velocity can be obtained through model calculation so as to judge the artery function and judge whether a person to be measured is arteriosclerosis; and the result is accurate.
Detailed Description
The experimental procedures used in the following examples are all conventional procedures unless otherwise specified.
Materials, reagents and the like used in the following examples are commercially available unless otherwise specified.
Examples 1,
1. Study subjects: volunteers who volunteered to participate in the study were enrolled by way of recruitment or the like, with unlimited age, gender, and health. The following groups were excluded: the method comprises the following steps of firstly, the mental disease people, namely people who have serious peripheral arterial occlusive lesions and cannot complete PWV detection of right carotid artery, right upper limb artery, right iliac artery and femoral artery, and people who frequently have premature beat, atrial fibrillation and the like and cannot obtain regular sinus rhythm in the detection process refuse to sign informed consent. All enrollees had to sign informed consent before the study began.
2. Detecting the index
2.2.1 general data: collecting the sex, birth date and past medical history of the subject.
2.2.2 clinical indexes:
1) the blood pressure measuring method comprises the following steps: the panelists measured the blood pressure of the sitting position of the right upper arm after resting for at least 15 minutes, 2 times in total, with 1 minute intervals, and the average of the 2 readings was taken as the final blood pressure value. For example, 2 readings of systolic or diastolic blood pressure differ by more than 5mmHg, and are measured again and averaged over 3 readings. The measurement was performed using a mercury column sphygmomanometer.
2) The measuring method of abdominal circumference and body mass index comprises the following steps: the selected person is in the upright position, the hands naturally droop, the middle point of the connecting line of the anterior upper iliac crest and the lower edge of the 12 th rib is taken to surround the abdomen, the tape is attached to the skin without applying pressure, and the measurement is accurate to 0.1 cm. Body weight and height were measured simultaneously and Body Mass Index (BMI) was calculated.
2.2.3 vascular function index:
applications of
The Pulse wave velocity (Pulse wave velocity) was measured by the Pulse wave velocity measuring system, and the examinee was in a quiet room and in a lying position to measure the carotid-femoral Pulse wave velocity (cf-PWV). The subjects had a rest of at least 15 minutes before the assay to avoid emotional agitation, strenuous exercise, smoking, tea and coffee.
2.2.4 model parameter calculation:
the collected data including sex, blood pressure, height and weight of the testee are used, and the estimated systemic vascular resistance is calculated by adopting a formula II;
formula II: the systemic vascular resistance of the whole population is 1659-55.299 × sex-134.591 × age group (30-44 years) -24.746 × age group (45-54 years) -30.954 × body mass index-7.459 × abdominal circumference/body mass index +6.974 × systolic pressure-3.967 × pulse pressure difference;
in the formula II, when the person to be tested represents a male, the sex value is 1; when the person to be tested represents a woman, the sex value is 0; when the age is 30-44 years, the numerical value of the age group (30-44 years) is 1, and the numerical value of the age group (45-54 years) is 0; when the age is 45-54 years, the numerical value of the age group (45-54 years) is 1, and the numerical value of the age group (30-44 years) is 0; abdominal circumference is in centimeters, and weight index is weight/height2The unit: kilogram/meter2(ii) a Systolic blood pressure is in mmHg; the pulse pressure difference is the value of diastolic pressure minus systolic pressure, and the unit of diastolic pressure is mmHg.
The previously available patents were used to calculate Systemic Vascular Resistance (SVR), Systemic Vascular Compliance (SVC), Brachial Artery Distensibility (BAD) in the population.
The systemic vascular compliance of the whole population is calculated according to the following formula:
SVC 0.9137+0.0502 × gender +0.0942 × age group (30-44 years) +0.0444 × age group (45-54 years) +0.0329 × body mass index +0.0480 × abdominal circumference/body mass index-0.0041 × systolic blood pressure-0.0043 × pulse differential pressure;
wherein, when the person to be measured represents a male, the sex value is 1; when the person to be tested represents a woman, the sex value is 0;
the full population brachial artery distensibility is calculated according to the following formula:
SVC 10.429+0.236 Xgender +0.316 Xage group (30-44 years) +0.036 Xage group (45-54 years) -0.027 Xbody mass index-0.151 Xabdominal circumference/body mass index-0.019 Xsystolic pressure-0.022 Xpulse differential pressure
2.3. Statistical analysis:
the software used for statistical analysis was SPSS17 statistical software. The statistical tests used for the data were all two-sided tests, and a P value less than 0.05 would be considered statistically significant for the differences tested. Description of quantitative indicators mean, standard deviation, median, minimum, maximum, lower quartile (Q1), upper quartile (Q3), classification indicators describe the number of cases and percentage of each class. Significance level of study: the level of statistical significance was 0.05, with assay potency of 95%.
3. Results
3.1 general data on subjects: the general indexes of the subjects are shown in Table 1 after the subjects are combined into 450 cases.
TABLE 1 general conditions of the subjects (mean. + -. standard deviation)
BMI: body mass index, SBP: systolic blood pressure, DBP: diastolic pressure, SVR: systemic vascular resistance, SVC: systemic vascular compliance, BAD: brachial artery distensibility, cf-PWV: carotid-femoral pulse wave velocity
3.2 correlation analysis of Observation indicators with cf-PWV
The observation indexes and the artery elasticity indexes have obvious correlation among all indexes of the artery elasticity, and the correlation with the age, the body mass index, the abdominal circumference and the blood pressure is obvious as shown in a table 2.
TABLE 2 correlation analysis results of cf-PWV isoarterial elasticity index and observation index
BMI: body mass index, SBP: systolic blood pressure, DBP: diastolic pressure, SVR: systemic vascular resistance, SVC: systemic vascular compliance, BAD: brachial artery distensibility, cf-PWV: carotid-femoral pulse wave velocity; represents P value < 0.01
3.3 multiple regression analysis and equation establishment
The results of multiple linear regression analysis of the above observation indexes using cf-PWV as a dependent variable showed that the regression equation (see table 3) established by sex, age, systolic blood pressure, heart rate, abdominal circumference/BMI, and SVR fit perfectly, the R value was 0.803, the R square was 0.644, the adjusted R square was 0.640, the standard error of the predicted value of the dependent variable was 1.335, F was 133.764, and P was 0.000.
TABLE 3 cf-PWV multiple Linear regression analysis results
The estimated cf-PWV from the regression equation is given as:
cf-PWV-3.789 +0.278 gender +0.075 × age +0.055 × systolic blood pressure +0.024 × Heart Rate +1.280 × Abdominal circumference/body Mass index-0.003 × estimated systemic vascular resistance
In the formula I, cf-PWV represents the carotid-femoral pulse wave conduction velocity; when the person to be tested represents a male, the sex value is 1; when the person to be tested represents a woman, the sex value is 0; abdominal circumference is in centimeters, and weight index is weight/height2The unit: kilogram/meter2(ii) a Age in units of years; the units of systolic pressure and diastolic pressure are mmHg; heart rate in units of beats/minute;
in formula I, the estimated systemic vascular resistance is calculated according to formula II below:
formula II: the systemic vascular resistance of the whole population is 1659-55.299 × sex-134.591 × age group (30-44 years) -24.746 × age group (45-54 years) -30.954 × body mass index-7.459 × abdominal circumference/body mass index +6.974 × systolic pressure-3.967 × pulse pressure difference;
in the formula II, when the person to be tested represents a male, the sex value is 1; when the person to be tested represents a woman, the sex value is 0; when the age is 30-44 years, the numerical value of the age group (30-44 years) is 1, and the numerical value of the age group (45-54 years) is 0; when the age is 45-54 years, the numerical value of the age group (45-54 years) is 1, and the numerical value of the age group (30-44 years) is 0; abdominal circumference is in centimeters, and weight index is weight/height2The unit: kilogram/meter2(ii) a Systolic blood pressure is in mmHg; the pulse pressure difference is the value of diastolic pressure minus systolic pressure, and the unit of diastolic pressure is mmHg.
The judgment threshold of cf-PWV was 12 m/s.
If the carotid artery-femoral artery pulse wave conduction velocity cf-PWV value is greater than or equal to the judgment threshold value of 12m/s, the person to be tested is or is selected as the arteriosclerosis patient; otherwise, the subject is not, or is not a candidate for, an arteriosclerotic patient.
Claims (10)
1. A data processing device for aiding in the assessment of arteriosclerosis, comprising the following modules:
(1) a data receiving module; the data receiving module is configured to receive gender, age, systolic blood pressure, heart rate, abdominal circumference, body mass index, estimated systemic vascular resistance data of the person under test;
(B) a data operation module; the data operation module is configured to receive the data from the data receiving module and is configured to calculate a value of the carotid-femoral pulse wave velocity according to the following formula I according to the gender, the age, the systolic blood pressure, the heart rate, the abdominal circumference, the body mass index and the estimated systemic vascular resistance value;
formula I: cf-PWV-3.789 +0.278 × gender +0.075 × age +0.055 × systolic blood pressure +0.024 × heart rate +1.280 × abdominal circumference/body mass index-0.003 × estimated systemic vascular resistance;
in the formula I, cf-PWV represents the carotid-femoral pulse wave conduction velocity; when the person to be tested represents a male, the sex value is 1; when the person to be tested represents a woman, the sex value is 0; abdominal circumference is in centimeters, and weight index is weight/height2The unit: kilogram/meter2(ii) a Age in units of years; the units of systolic pressure and diastolic pressure are mmHg; heart rate in units of beats/minute;
(3) a data storage module; the data storage module is configured to store a decision threshold;
(4) a data comparison module; the data comparison module is configured to receive the carotid-femoral pulse wave velocity value sent by the operation module and call the judgment threshold value from the data storage module to compare with the carotid-femoral pulse wave velocity value;
(5) a judgment module; the judging module is configured to receive the comparison result sent by the data comparing module, judge the comparison result according to a preset judging condition, judge the person to be tested who meets the preset judging condition as an arteriosclerosis patient or a candidate of the person to be tested who does not meet the preset judging condition as the arteriosclerosis patient, judge the person to be tested who does not meet the preset judging condition as the arteriosclerosis patient or the candidate of the person to be tested who does not meet the preset judging condition as the arteriosclerosis patient, and output the judgment result.
2. The data processing apparatus of claim 1, wherein: the predetermined determination condition is: if the carotid-femoral pulse wave velocity value is larger than or equal to the judgment threshold, the person to be detected is or is selected as the arteriosclerosis patient; otherwise, the subject is not or is not a candidate for an arteriosclerosis patient;
and/or
The judgment threshold value stored in the data storage module is 12 m/s.
3. The data processing apparatus according to claim 1 or 2, characterized in that: in formula I, the estimated systemic vascular resistance is calculated according to formula II below:
formula II: the systemic vascular resistance of the whole population is 1659-55.299 × sex-134.591 × age group (30-44 years) -24.746 × age group (45-54 years) -30.954 × body mass index-7.459 × abdominal circumference/body mass index +6.974 × systolic pressure-3.967 × pulse pressure difference;
in the formula II, when the person to be tested represents a male, the sex value is 1; when the person to be tested represents a woman, the sex value is 0; when the age is 30-44 years, the numerical value of the age group (30-44 years) is 1, and the numerical value of the age group (45-54 years) is 0; when the age is 45-54 years, the numerical value of the age group (45-54 years) is 1, and the numerical value of the age group (30-44 years) is 0; abdominal circumference is in centimeters, and weight index is weight/height2The unit: kilogram/meter2(ii) a Systolic blood pressure is in mmHg; the pulse pressure difference is the value of diastolic pressure minus systolic pressure, and the unit of diastolic pressure is mmHg.
4. A data processing apparatus according to any one of claims 1-3, characterized in that: the data processing device further comprises a control module or a controller; the control module or the controller is used for controlling each module.
5. An arteriosclerosis auxiliary evaluation system comprises a blood pressure meter, a flexible rule, a weight scale, a timing device and a control device;
the control device is configured or programmed to perform the steps of:
receiving sex, age, systolic blood pressure, heart rate, abdominal circumference, body mass index and estimated systemic vascular resistance data of a person to be detected;
calculating a carotid-femoral pulse wave velocity value according to the following formula I according to the gender, the age, the systolic blood pressure, the heart rate, the abdominal circumference, the body mass index and the estimated systemic vascular resistance value;
formula I: cf-PWV-3.789 +0.278 × gender +0.075 × age +0.055 × systolic blood pressure +0.024 × heart rate +1.280 × abdominal circumference/body mass index-0.003 × estimated systemic vascular resistance;
in the formula I, cf-PWV represents the carotid-femoral pulse wave conduction velocity; when the person to be tested represents a male, the sex value is 1; when the person to be tested represents a woman, the sex value is 0; abdominal circumference is in centimeters, and weight index is weight/height2The unit: kilogram/meter2(ii) a Age in units of years; the units of systolic pressure and diastolic pressure are mmHg; heart rate in units of beats/minute;
comparing the carotid-femoral pulse wave velocity value with a judgment threshold value to obtain a comparison result;
and judging the comparison result according to a preset judgment condition, judging that the person to be tested meeting the preset judgment condition is or is not a patient suffering from arteriosclerosis, judging that the person to be tested not meeting the preset judgment condition is or is not a patient suffering from arteriosclerosis, and outputting the judgment result.
6. The system of claim 5, wherein: the system further comprises:
the system further comprises an input device and an output device;
the input device is configured to input the systolic blood pressure, the heart rate, the abdominal circumference, the body mass index and the estimated systemic vascular resistance data of the subject collected by the sphygmomanometer, a tape, a weight scale, a timing device, respectively;
the output device is configured to output the determination result.
7. Method of use of the system of claim 5 or 6, comprising the steps of: obtaining the systolic blood pressure, the heart rate, the abdominal circumference, the body mass index, the estimated systemic vascular resistance data of the subject using (a1) - (a3) as follows; then executing the steps by using the control device in the system according to claim 5 or 6, and outputting the determination result;
(a1) a blood pressure monitor;
(a2) a flexible rule;
(a3) weighing;
(a4) a timing device.
8. A computer-readable storage medium storing a computer program for performing the steps of:
receiving sex, age, systolic blood pressure, heart rate, abdominal circumference, body mass index and estimated systemic vascular resistance data of a person to be detected;
calculating a carotid-femoral pulse wave velocity value according to the following formula I according to the gender, the age, the systolic blood pressure, the heart rate, the abdominal circumference, the body mass index and the estimated systemic vascular resistance value;
formula I: cf-PWV-3.789 +0.278 × gender +0.075 × age +0.055 × systolic blood pressure +0.024 × heart rate +1.280 × abdominal circumference/body mass index-0.003 × estimated systemic vascular resistance;
in the formula I, cf-PWV represents the carotid-femoral pulse wave conduction velocity; when the person to be tested represents a male, the sex value is 1; when the person to be tested represents a woman, the sex value is 0; abdominal circumference is in centimeters, and weight index is weight/height2The unit: kilogram/meter2(ii) a Age in units of years; the units of systolic pressure and diastolic pressure are mmHg; heart rate in units of beats/minute;
comparing the carotid-femoral pulse wave velocity value with a judgment threshold value to obtain a comparison result;
and judging the comparison result according to a preset judgment condition, judging that the person to be tested meeting the preset judgment condition is or is not a patient suffering from arteriosclerosis, judging that the person to be tested not meeting the preset judgment condition is or is not a patient suffering from arteriosclerosis, and outputting the judgment result.
9. A kit for aiding in the assessment of arteriosclerosis comprising a parameter acquisition device and a readability carrier;
the parameter acquisition device comprises a device for acquiring various parameters involved in the readability carrier;
the readability carrier has the following formula I,
formula I: cf-PWV-3.789 +0.278 × gender +0.075 × age +0.055 × systolic blood pressure +0.024 × heart rate +1.280 × abdominal circumference/body mass index-0.003 × estimated systemic vascular resistance;
in the formula I, cf-PWV represents the carotid-femoral pulse wave conduction velocity; when the person to be tested represents a male, the sex value is 1; when the person to be tested represents a woman, the sex value is 0; abdominal circumference is in centimeters, and weight index is weight/height2The unit: kilogram/meter2(ii) a Age in units of years; the units of systolic pressure and diastolic pressure are mmHg; heart rate in units of beats/minute;
if the carotid-femoral pulse wave velocity value is larger than or equal to the judgment threshold, the person to be detected is or is selected as the arteriosclerosis patient; otherwise, the subject is not, or is not a candidate for, an arteriosclerotic patient.
10. The kit of claim 9, wherein: the parameter acquisition equipment comprises a blood pressure meter, a flexible rule, a weight scale and a timing device; and/or
The kit further comprises recording means and/or calculation means; the recording tool comprises a pen and/or a computer; the computing tool comprises a calculator and/or the computer; and/or
The readable carrier is a kit instruction; the content of formula I is printed on a card; and/or
The readable carrier is a computer readable carrier.
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| CN202111073055 | 2021-09-14 | ||
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