CN113876744A - Sanfu plaster for treating chronic bronchitis and preparation method thereof - Google Patents

Sanfu plaster for treating chronic bronchitis and preparation method thereof Download PDF

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CN113876744A
CN113876744A CN202111295067.9A CN202111295067A CN113876744A CN 113876744 A CN113876744 A CN 113876744A CN 202111295067 A CN202111295067 A CN 202111295067A CN 113876744 A CN113876744 A CN 113876744A
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patch
rhizoma
chronic bronchitis
sanfu
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钱建国
史宝光
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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Abstract

The invention discloses a Sanfu plaster for treating chronic bronchitis and a preparation method thereof, belonging to the technical field of traditional Chinese medicine treatment. The traditional Chinese medicine composition adopted in the Sanfu plaster is prepared from the following raw material medicines: semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari, radix kansui and rhizoma Zingiberis recens juice. The Sanfu plaster is used for treating chronic bronchitis by adopting the treatment principle of expelling wind and eliminating evil, relieving cough and reducing sputum of traditional Chinese medicine, wherein the white mustard seed is warm in nature and pungent in taste, enters lung channels and stomach channels, promotes qi circulation and dryness-phlegm, and is a monarch drug for resolving masses and reducing swelling; rhizoma corydalis has effects of promoting blood circulation, removing blood stasis, regulating qi-flowing and relieving pain; the asarum can expel wind, dispel cold, dredge orifices, relieve pain, warm lung and eliminate phlegm; the dried ginger, the white mustard seed and the white mustard seed are used for dispelling cold and reducing phlegm. Kansui root, radix kansui, as an adjuvant drug and ginger juice, has the effects of purging water and resolving fluid retention, dispersing swelling and dissipating nodulation, dispelling cold and relieving exterior syndrome, as a guiding drug, assisting transportation and transformation, and harmonizing the other drugs. The traditional Chinese medicine composition has the effects of warming the interior, dispelling cold, promoting diuresis, eliminating phlegm, warming the channels, dredging collaterals and stimulating acupuncture points by combining the medicines.

Description

Sanfu plaster for treating chronic bronchitis and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicine treatment, in particular to a Sanfu patch for treating chronic bronchitis and a preparation method thereof.
Background
The chronic bronchitis is the most common chronic inflammatory pathological changes of the respiratory tract, the main diseased parts are the bronchus, the trachea and the mucous tissues around the bronchus, the disease is easy to relapse, and the cure difficulty is higher. At present, the western medicine mainly aims at relieving cough, eliminating phlegm, relieving asthma and resisting inflammation for the chronic bronchitis, and can relieve the clinical symptoms of patients, but the condition of the patients cannot be reversed, and the lung function is continuously reduced. The chronic bronchitis is classified into 'asthma syndrome' and 'cough' in the traditional Chinese medicine, the causes of the chronic bronchitis are external six excesses of pathogenic toxin and dysfunction of internal organs, wind pathogen in six excesses is the long of a hundred diseases, the lung is delicate and delicate, the wind pathogen attacks the lung, the lung is caused to lose and descend, the lung qi is upward adverse, the wind pathogen is removed but not exhausted, and the cough is caused to repeatedly attack and delay and heal.
The cold weather in autumn and winter easily causes repeated attack of clinical symptoms of patients with chronic bronchitis, the traditional Chinese medicine advocates treatment in winter in summer, and the three-volt day is the most vigorous yang qi, so that the traditional Chinese medicine has positive significance in treating lung lesions. At present, sanfu plaster for treating chronic bronchitis is available, but the efficacy is not obvious and the treatment effect is not obvious.
Disclosure of Invention
The invention aims to provide a Sanfu paste for treating chronic bronchitis and a preparation method thereof, and aims to solve the problems that the existing Sanfu paste for treating chronic bronchitis is not obvious in effect and not obvious in treatment effect.
The technical scheme for solving the technical problems is as follows:
a traditional Chinese medicine composition adopted in the Sanfu patch is prepared from the following raw material medicines: semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari, radix kansui and rhizoma Zingiberis recens juice;
wherein the mass ratio of white mustard seed, corydalis tuber, dried ginger, asarum and kansui root is (0.5-2): (2-4): 1-3): 2-4.
Further, the traditional Chinese medicine composition adopted in the sanfu patch for treating chronic bronchitis is prepared from the following raw material medicines: semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari, radix kansui and rhizoma Zingiberis recens juice;
wherein the mass ratio of white mustard seed, corydalis tuber, dried ginger, asarum and euphorbia kansui is (0.5-1.5): (2.5-3.5): (1.5-2.5): 2.5-3.5.
Further, the traditional Chinese medicine composition adopted in the sanfu patch for treating chronic bronchitis is prepared from the following raw material medicines: semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari, radix kansui and rhizoma Zingiberis recens juice;
wherein the mass ratio of the white mustard seed to the corydalis tuber to the dried ginger to the asarum to the euphorbia kansui is 1:3:2:3: 3.
Furthermore, in the traditional Chinese medicine composition adopted by the Sanfu patch, the mass ratio of the ginger juice to the total mass of the white mustard seed, the corydalis tuber, the dried ginger, the asarum and the euphorbia kansui is (1-1.5): 1.
The invention also provides a preparation method of the Sanfu patch for treating chronic bronchitis, which comprises the following steps:
(1) pulverizing semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari and radix kansui, and sieving to obtain medicinal powder;
(2) mixing rhizoma Zingiberis recens juice with the medicinal powder, and concocting into paste to obtain unguent;
(3) the ointment is prepared into a medicament which is attached to the center of the thin patch, and a protective patch is attached to the thin patch to obtain the Sanfu patch for treating the chronic bronchitis.
Further, the powder crushed in the step (1) is sieved by a 100-120-mesh sieve.
Further, the dosage form prepared in step (3) is 2cm × 2cm, 1g, and is suitable for children. In the present invention, the child is directed to a child under the age of 12 years.
Further, the size of the medicament prepared in the step (3) is 3cm multiplied by 3cm, 1.5g, and the medicament is used for adults. In the present invention, the adult is aimed at the age of 13 years or more.
White mustard seed, the name of traditional Chinese medicine. Is seed of Brassicaceae plant caulis et folium Sinapis Albae. Has effects of warming lung, eliminating phlegm, activating qi-flowing, resolving hard mass and relieving swelling. It is mainly used for treating cold phlegm cough and asthma, fluid retention, dorsal furuncle, multiple abscess, numbness of limbs, and arthralgia. The seeds contain glucosinolates and are filled with sinapioside. It also contains fatty oil, myrosinase, sinapine and lysine, arginine, histidine, etc. Also contains 4-hydroxybenzoyl choline and 4-hydroxybenzyl methylamine. The pharmacological effects are as follows: respiratory system effects: a small dose can cause reflex tracheal secretion to increase, and has the effects of nausea and phlegm elimination. Effect on skin mucosa: the Sinapis Albae oil obtained by hydrolyzing sinapioside has strong irritation, and can be used for treating skin hyperemia and foaming. Effects on the digestive system: the semen Sinapis Albae powder has effects of promoting salivary secretion, increasing amylase activity, stimulating gastric mucosa in small amount, increasing secretion of gastric juice and pancreatic juice, and promoting vomiting in large amount. Role of pathogenic microorganisms: the water infusion has effect in inhibiting dermatophytes.
Corydalis tuber, name of Chinese medicine. Is dried tuber of corydalis of Papaveraceae. Has effects in promoting blood circulation, activating qi-flowing, and relieving pain. It is mainly indicated for various pain syndromes due to qi and blood stagnation. Such as thoracic obstruction, heart pain, liver and stomach pain, dysmenorrhea, menoxenia, puerperal abdominal pain due to blood stasis, cold hernia, traumatic injury, swelling pain due to blood stasis, and rheumatalgia. Contains alkaloids (corydalis A, B, C, D, G, C, N, and S), starch, mucilage, resin, volatile oil, and neutral substance. The pharmacological effects are as follows: effects on the nervous system: tetrahydropalmatine has analgesic, hypnotic, tranquilizing, and tranquilizing effects. The A and the Pharbitidis have obvious analgesic effect and certain hypnotic, sedative and tranquilization effects. Influence on the circulation system: the alcohol extract of rhizoma corydalis can dilate coronary artery, reduce coronary artery resistance, increase coronary artery flow, and improve anoxia resistance. The rhizoma corydalis total alkaloids have effects of resisting arrhythmia and myocardial ischemia, dilating peripheral blood vessel, lowering blood pressure, and slowing down heart rate. Effects on the digestive system: the rhizoma corydalis total alkaloids have antiulcer and gastric secretion inhibiting effects. The rhizoma corydalis extract has exciting effect on guinea pig isolated intestine, and can resist 5-hydroxytryptamine induced shrinkage of rat isolated stomach and colon. Effects on the endocrine System: promote the pituitary gland of the rat to secrete adrenocorticotropic hormone, influence the function of the thyroid gland and increase the weight of the thyroid gland. In addition, Yanhusuo has the actions of relaxing muscles, stopping vomiting and reducing body temperature.
Dried ginger, named as traditional Chinese medicine. Is dried rhizome of Zingiber officinale Roscoe of Zingiberaceae. Has the effects of warming spleen and stomach for dispelling cold, restoring yang and dredging collaterals, and warming lung and resolving fluid retention. It can be used for treating abdominal psychroalgia, emesis, diarrhea, yang exhaustion, cough and asthma due to cold-fluid retention, and arthralgia due to cold-dampness. Contains volatile oil about 2%, and mainly contains zingiberene, phellandrene, camphene, zingiberone, gingerol, zingiberone, borneol, gingerol, citral, etc. It also contains resin, starch and amino acids. The pharmacological effects are as follows: has tranquilizing, analgesic, antiinflammatory, anticoagulant, anoxia resisting, and other effects, and is effective in treating cardiovascular and adrenal cortex function and digestive system function.
Asarum herb, the name of traditional Chinese medicine. Is the whole herb of Aristolochiaceae plant Asarum sieboldii. Has effects of dispelling pathogenic wind, dispelling cold, inducing resuscitation, relieving pain, warming lung, and eliminating phlegm. It is used to treat wind-cold type common cold, headache, toothache, nasal obstruction, nasal sinusitis, rheumatic arthralgia, phlegm and fluid retention, asthma and cough. Contains volatile oil, and mainly contains methyl eugenol, eugenone, safrole, beta-pinene, alpha-pinene, borneol, isoanisole, asarinin, etc. In addition, contains racemization-potassium-removing lindera aggregate alkali. The trace elements include potassium, sodium, magnesium, calcium, iron, manganese, copper, zinc, etc. And further contains kaempferol, kaempferol 3-O-beta-D-glucopyranoside, gamma-terpinene, beta-terpinene, alpha-arborvitae, asarone and (-) -asarone.
Gan sui, the name of traditional Chinese medicine. Is root tuber of Euphorbia kansui of Euphorbiaceae. Has the effects of purging water, expelling retained fluid, relieving swelling, and dispersing pathogenic accumulation. It is indicated for edema, abdominal dropsy, phlegm and fluid accumulation, dyspnea with cough, difficult urination and defecation. The product contains euphadienol, alpha-euphol, kansui alcohol, gamma-cirsium japonicum sterol, kansui sterol and alpha-cirsium japonicum sterol. It has also been reported that the roots still contain derivatives (I), (II) of 20-deoxyingenol, derivatives (III) of ingenol, derivatives (IV) of 13-oxoingenol, euphorbia kansui terpene ester A and euphorbia kansui terpene ester B, all of which are toxic, and beta-sitosterol.
Ginger juice, named as Chinese medicinal material. The product is prepared by cleaning rhizoma Zingiberis recens of Zingiberaceae, mashing, and mixing with juice. The main functional indications are as follows: has the effects of dispelling cold, relieving exterior syndrome, lowering adverse qi, relieving vomit, eliminating phlegm and relieving cough, and can be used for treating nausea, emesis, cough and excessive phlegm.
The invention has the following beneficial effects:
the Sanfu plaster is used for treating chronic bronchitis by adopting the treatment principle of expelling wind and eliminating evil, relieving cough and reducing sputum of traditional Chinese medicine, wherein the white mustard seed is warm in nature and pungent in taste, enters lung channels and stomach channels, promotes qi circulation and dryness-phlegm, and is a monarch drug for resolving masses and reducing swelling; rhizoma corydalis has effects of promoting blood circulation, removing blood stasis, regulating qi-flowing and relieving pain; the asarum can expel wind, dispel cold, dredge orifices, relieve pain, warm lung and eliminate phlegm; the dried ginger, the white mustard seed and the white mustard seed are used for dispelling cold and reducing phlegm. Kansui root, radix kansui, as an adjuvant drug and ginger juice, has the effects of purging water and resolving fluid retention, dispersing swelling and dissipating nodulation, dispelling cold and relieving exterior syndrome, as a guiding drug, assisting transportation and transformation, and harmonizing the other drugs. The traditional Chinese medicine composition has the effects of warming the interior, dispelling cold, promoting diuresis, eliminating phlegm, warming the channels, dredging collaterals and stimulating acupuncture points by combining the medicines.
Detailed Description
The principles and features of this invention are described below in conjunction with embodiments, which are included to explain the invention and not to limit the scope of the invention. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
Example 1:
the traditional Chinese medicine composition adopted in the sanfu patch for treating chronic bronchitis in the embodiment is prepared from the following raw material medicines: semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari, radix kansui and rhizoma Zingiberis recens juice;
wherein the mass ratio of white mustard seed, corydalis tuber, dried ginger, asarum and euphorbia kansui is 0.5:2:1: 2.
The mass ratio of the ginger juice to the total mass of the white mustard seed, the corydalis tuber, the dried ginger, the asarum and the euphorbia kansui is 1: 1.
The preparation method of the patch for treating chronic bronchitis in the embodiment comprises the following steps:
(1) pulverizing semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari and radix kansui, and sieving with 100 mesh sieve to obtain medicinal powder;
(2) mixing rhizoma Zingiberis recens juice with the medicinal powder, and concocting into paste to obtain unguent;
(3) the ointment is prepared into a medicament which is attached to the center of the thin patch, and a protective patch is attached to the thin patch to obtain the Sanfu patch for treating the chronic bronchitis.
The specification of the medicament prepared in the step (3) of the invention is 2cm multiplied by 2cm, 1g, and the medicament is used for children; or 3cm × 3cm, 1.5g, for adults.
Example 2:
the traditional Chinese medicine composition adopted in the sanfu patch for treating chronic bronchitis in the embodiment is prepared from the following raw material medicines: semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari, radix kansui and rhizoma Zingiberis recens juice;
wherein the mass ratio of the white mustard seed to the corydalis tuber to the dried ginger to the asarum to the euphorbia kansui is 0.5:2.5:1.5:1.5: 2.5.
The mass ratio of the ginger juice to the total mass of the white mustard seed, the corydalis tuber, the dried ginger, the asarum and the euphorbia kansui is 1.2: 1.
The preparation method of the patch for treating chronic bronchitis in the embodiment comprises the following steps:
(1) pulverizing semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari and radix kansui, and sieving with 100 mesh sieve to obtain medicinal powder;
(2) mixing rhizoma Zingiberis recens juice with the medicinal powder, and concocting into paste to obtain unguent;
(3) the ointment is prepared into a medicament which is attached to the center of the thin patch, and a protective patch is attached to the thin patch to obtain the Sanfu patch for treating the chronic bronchitis.
The specification of the medicament prepared in the step (3) of the invention is 2cm multiplied by 2cm, 1g, and the medicament is used for children; or 3cm × 3cm, 1.5g, for adults.
Example 3:
the traditional Chinese medicine composition adopted in the sanfu patch for treating chronic bronchitis in the embodiment is prepared from the following raw material medicines: semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari, radix kansui and rhizoma Zingiberis recens juice;
wherein the mass ratio of the white mustard seed to the corydalis tuber to the dried ginger to the asarum to the euphorbia kansui is 1:3:2:3: 3.
The mass ratio of the ginger juice to the total mass of the white mustard seed, the corydalis tuber, the dried ginger, the asarum and the euphorbia kansui is 1.3: 1.
The preparation method of the patch for treating chronic bronchitis in the embodiment comprises the following steps:
(1) pulverizing semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari and radix kansui, and sieving with 110 mesh sieve to obtain medicinal powder;
(2) mixing rhizoma Zingiberis recens juice with the medicinal powder, and concocting into paste to obtain unguent;
(3) the ointment is prepared into a medicament which is attached to the center of the thin patch, and a protective patch is attached to the thin patch to obtain the Sanfu patch for treating the chronic bronchitis.
The specification of the medicament prepared in the step (3) of the invention is 2cm multiplied by 2cm, 1g, and the medicament is used for children; or 3cm × 3cm, 1.5g, for adults.
Example 4:
the traditional Chinese medicine composition adopted in the sanfu patch for treating chronic bronchitis in the embodiment is prepared from the following raw material medicines: semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari, radix kansui and rhizoma Zingiberis recens juice;
wherein the mass ratio of the white mustard seed to the corydalis tuber to the dried ginger to the asarum to the euphorbia kansui is 1.5:3.5:2.5:2.5: 3.5.
The mass ratio of the ginger juice to the total mass of the white mustard seed, the corydalis tuber, the dried ginger, the asarum and the euphorbia kansui is 1.4: 1.
The preparation method of the patch for treating chronic bronchitis in the embodiment comprises the following steps:
(1) crushing white mustard seed, corydalis tuber, dried ginger, asarum and kansui root, and sieving by a sieve of 100-120 meshes to obtain medicinal powder;
(2) mixing rhizoma Zingiberis recens juice with the medicinal powder, and concocting into paste to obtain unguent;
(3) the ointment is prepared into a medicament which is attached to the center of the thin patch, and a protective patch is attached to the thin patch to obtain the Sanfu patch for treating the chronic bronchitis.
The specification of the medicament prepared in the step (3) of the invention is 2cm multiplied by 2cm, 1g, and the medicament is used for children; or 3cm × 3cm, 1.5g, for adults.
Example 5:
the traditional Chinese medicine composition adopted in the sanfu patch for treating chronic bronchitis in the embodiment is prepared from the following raw material medicines: semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari, radix kansui and rhizoma Zingiberis recens juice;
wherein the mass ratio of the white mustard seed to the corydalis tuber to the dried ginger to the asarum to the euphorbia kansui is 2:4:3:3: 4.
The mass ratio of the ginger juice to the total mass of the white mustard seed, the corydalis tuber, the dried ginger, the asarum and the euphorbia kansui is 1.5:1.
The preparation method of the patch for treating chronic bronchitis in the embodiment comprises the following steps:
(1) pulverizing semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari and radix kansui, and sieving with 120 mesh sieve to obtain medicinal powder;
(2) mixing rhizoma Zingiberis recens juice with the medicinal powder, and concocting into paste to obtain unguent;
(3) the ointment is prepared into a medicament which is attached to the center of the thin patch, and a protective patch is attached to the thin patch to obtain the Sanfu patch for treating the chronic bronchitis.
The specification of the medicament prepared in the step (3) of the invention is 2cm multiplied by 2cm, 1g, and the medicament is used for children; or 3cm × 3cm, 1.5g, for adults.
The compatible acupuncture points of the Sanfu patch for treating chronic bronchitis in the invention are selected from the following components: the large spine, lung, heart, septum and Tiantu.
Use contraindications: pregnant women, pulmonary tuberculosis, severe cardiopulmonary function diseases, severe hypertension, and diabetes.
Note that: the patch is applied to children 3-14 years old for 1-2 hours, and the patch is applied to children above 14 years old for 2-4 hours.
Application cases are as follows:
1. when a certain woman in the family is 88 years old and patients have serious tracheitis, cough and asthma continue for about one month when weather changes, the Sanfu paste disclosed by the invention is pasted from 09 years, and the symptoms of the patients are obviously relieved after the Sanfu paste is continuously pasted for three years, so far, the Sanfu paste is continuously pasted for 13 years.
2. Xuan, male, 52 years old, patient will have tracheitis from childhood, cough, expectoration with wheezing will appear in winter every year about two months, from 09 years, the three-volt patch of the invention is attached, symptoms basically disappear after three years of continuous attachment, and then 10 years of continuous attachment, so far, there is no cough for several days in winter.
3. When a certain male is in the age of 68, the patient suffers from cough, cough with large amount of phlegm, wheeze and the like after being cooled, the cough frequency is obviously reduced compared with the prior art after the three-volt patch is attached for the second year from 09 years, the cough time and symptoms are obviously relieved, and the symptoms basically disappear after the three-volt patch is continuously attached for four years.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims (8)

1. The Sanfu patch for treating chronic bronchitis is characterized in that a traditional Chinese medicine composition adopted in the Sanfu patch is prepared from the following raw material medicines: semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari, radix kansui and rhizoma Zingiberis recens juice;
wherein the mass ratio of white mustard seed, corydalis tuber, dried ginger, asarum and kansui root is (0.5-2): (2-4): 1-3): 2-4.
2. The patch for treating chronic bronchitis according to claim 1, wherein the traditional Chinese medicine composition adopted in the patch is prepared from the following raw material medicines: semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari, radix kansui and rhizoma Zingiberis recens juice;
wherein the mass ratio of white mustard seed, corydalis tuber, dried ginger, asarum and euphorbia kansui is (0.5-1.5): (2.5-3.5): (1.5-2.5): 2.5-3.5.
3. The patch for treating chronic bronchitis according to claim 2, wherein the traditional Chinese medicine composition adopted in the patch is prepared from the following raw material medicines: semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari, radix kansui and rhizoma Zingiberis recens juice;
wherein the mass ratio of the white mustard seed to the corydalis tuber to the dried ginger to the asarum to the euphorbia kansui is 1:3:2:3: 3.
4. The patch for treating chronic bronchitis according to any one of claims 1 to 3, wherein the traditional Chinese medicine composition adopted by the patch is such that the mass ratio of the ginger juice to the total mass of white mustard seed, corydalis tuber, dried ginger, asarum and euphorbia kansui is (1-1.5): 1.
5. A method of preparing a patch for use in the treatment of chronic bronchitis according to any one of claims 1 to 4, comprising the steps of:
(1) pulverizing semen Sinapis Albae, rhizoma corydalis, Zingiberis rhizoma, herba asari and radix kansui, and sieving to obtain medicinal powder;
(2) mixing rhizoma Zingiberis recens juice with the medicinal powder, and concocting into paste to obtain unguent;
(3) the ointment is prepared into a medicament which is attached to the center of the thin patch, and a protective patch is attached to the thin patch to obtain the Sanfu patch for treating the chronic bronchitis.
6. The preparation method of a Sanfu patch for treating chronic bronchitis according to claim 5, wherein the Sanfu patch is crushed in the step (1) and then screened by a 100-120-mesh sieve.
7. The method of claim 5, wherein the dosage form of step (3) is 2cm x 2cm, 1g for children.
8. The method of claim 5, wherein the dosage form of the patch prepared in step (3) is 3cm x 3cm, 1.5g, and is suitable for adults.
CN202111295067.9A 2021-11-03 2021-11-03 Sanfu plaster for treating chronic bronchitis and preparation method thereof Pending CN113876744A (en)

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CN104436084A (en) * 2013-09-13 2015-03-25 孟祥海 Acupoint application plaster for treating asthma and preparation method of acupoint application plaster
CN106581178A (en) * 2016-12-15 2017-04-26 忠县中医医院 Dog-days paste for preventing and treating asthma and preparation method of dog-days paste

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CN101810844A (en) * 2010-04-23 2010-08-25 浙江省中医院 External plaster for preventing disease and manufacturing method thereof
CN104436084A (en) * 2013-09-13 2015-03-25 孟祥海 Acupoint application plaster for treating asthma and preparation method of acupoint application plaster
CN106581178A (en) * 2016-12-15 2017-04-26 忠县中医医院 Dog-days paste for preventing and treating asthma and preparation method of dog-days paste

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