CN113855753A - Medicament for treating monkey trauma and preparation method thereof - Google Patents
Medicament for treating monkey trauma and preparation method thereof Download PDFInfo
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- CN113855753A CN113855753A CN202111410515.5A CN202111410515A CN113855753A CN 113855753 A CN113855753 A CN 113855753A CN 202111410515 A CN202111410515 A CN 202111410515A CN 113855753 A CN113855753 A CN 113855753A
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Abstract
The invention discloses a medicament for treating monkey trauma, which belongs to the technical field of primate culture, and has the characteristics of good treatment effect and quick wound healing by using the medicament to treat a wound of a monkey; the traditional Chinese medicine composition is a mixture prepared from the following traditional Chinese medicine raw materials in parts by weight: 2-4 g of borneol, 13-17 g of dragon's blood, 13-17 g of clematis root, 13-17 g of pseudo-ginseng powder, 13-17 g of salvia miltiorrhiza, 13-17 g of achyranthes bidentata, 13-17 g of loranthus parasiticus, 13-17 g of beautiful sweetgum fruit, 13-17 g of red paeony root, 13-17 g of Chinese angelica, 13-17 g of monkshood and 13-17 g of szechuan lovage rhizome. The invention also discloses a preparation method of the medicament.
Description
Technical Field
The invention relates to the technical field of primate culture, in particular to a medicament for treating monkey trauma and a preparation method of tea.
Background
Monkeys and humans share "primates" in zoology, are also very similar in their habit to humans, and their physical structure is most similar to that of humans. In many tests for drugs and foods at home and abroad, monkeys are used as test subjects so that test effects most similar to human reactions can be obtained. Therefore, the demand for experimental monkeys is large and requires special breeding. However, since monkeys are sexually active and active, and during the rearing process, a certain number of monkeys are usually housed in the same cage. At this time, a plurality of monkeys are gathered together inevitably to cause traumatic conditions, and the monkeys are generally coated with medicaments for treating human wounds at present, but the medicaments are not suitable for the monkeys, the use amount is not well controlled, if the dosage is small, the wounds heal slowly, and if the dosage is large, discomfort of the monkeys is easily caused, and even the growth of the monkeys is influenced. Therefore, it is highly desirable to invent a drug that can better treat wounds of monkeys, allow wounds to heal faster and better, and also do not affect their growth.
Disclosure of Invention
The invention aims to provide a medicament for treating monkey trauma, which is used for treating a monkey wound and has the characteristics of good treatment effect and quick wound healing. Another object of the present invention is to provide a process for the preparation of such a medicament.
The former technical scheme of the invention is as follows:
a medicament for treating monkey trauma is a mixture prepared from the following traditional Chinese medicine raw materials in parts by weight: 2-4 g of borneol, 13-17 g of dragon's blood, 13-17 g of clematis root, 13-17 g of pseudo-ginseng powder, 13-17 g of salvia miltiorrhiza, 13-17 g of achyranthes bidentata, 13-17 g of loranthus parasiticus, 13-17 g of beautiful sweetgum fruit, 13-17 g of red paeony root, 13-17 g of Chinese angelica, 13-17 g of monkshood and 13-17 g of szechuan lovage rhizome.
Further, the traditional Chinese medicine composition is a mixture prepared from the following traditional Chinese medicine raw materials in parts by weight: 3g of borneol, 15g of dragon's blood, 15g of clematis root, 15g of pseudo-ginseng powder, 15g of salvia miltiorrhiza, 15g of salted achyranthes root, 15g of parasitic loranthus, 15g of beautiful sweetgum fruit, 15g of red paeony root, 15g of Chinese angelica, 15g of monkshood and 15g of szechuan lovage rhizome.
Further, the mixture is powdery.
The latter technical scheme of the invention is as follows:
a preparation method of a medicament for treating monkey trauma comprises the following preparation steps:
(1) weighing dragon's blood, clematis root, salvia miltiorrhiza, salted achyranthes root, parasitic loranthus, beautiful sweetgum fruit, red paeony root, Chinese angelica, prepared common monkshood daughter root and szechuan lovage rhizome according to the parts by weight, and mixing;
(2) carrying out microwave drying on the mixed medicinal materials for 20-60 minutes, and then crushing into powder to obtain mixed medicinal powder;
(3) weighing borneol according to the weight parts, crushing the borneol and mixing the crushed borneol with the mixed powder obtained in the step (2).
Compared with the prior art, the invention has the beneficial effects that:
the medicament for treating the monkey trauma completely selects traditional Chinese medicine materials, and the medicament selects borneol, dragon's blood, clematis root, salvia miltiorrhiza, achyranthes bidentata, loranthus parasiticus, beautiful sweetgum fruit, red paeony root, Chinese angelica, prepared common monkshood daughter root and szechuan lovage rhizome. The dragon's blood in the medicinal materials can promote blood circulation, relieve pain, remove blood stasis, stop bleeding, heal wound and promote tissue regeneration; the clematis root, the parasitic loranthus and the beautiful sweetgum fruit have the function of dredging the channels and collaterals; notoginseng radix powder, Saviae Miltiorrhizae radix, Sal Achyranthis radix, radix Angelicae sinensis and rhizoma Ligustici Chuanxiong can promote blood circulation and remove blood stasis. After the medicinal materials are compatible and combined with each other, the healing of the trauma wound of the monkey can be effectively promoted, the treatment effect is obvious, and no side effect is generated on the monkey.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the invention and together with the description serve to explain the invention without limiting the invention. In the drawings:
FIG. 1 is a wound of a monkey nail in test example 1 at the time of injury;
FIG. 2 is a wound after treatment of a simian nail in Experimental example 1;
FIG. 3 shows the wounds after treatment of the simian nail in test example 1.
Detailed Description
The technical solution of the present invention will be described in further detail with reference to the following embodiments, but the present invention is not limited thereto.
Example 1
The invention relates to a medicament for treating monkey trauma, which is a mixture prepared from the following Chinese medicinal raw materials in parts by weight: 3g of borneol, 15g of dragon's blood, 15g of clematis root, 15g of pseudo-ginseng powder, 15g of salvia miltiorrhiza, 15g of salted achyranthes root, 15g of parasitic loranthus, 15g of beautiful sweetgum fruit, 15g of red paeony root, 15g of Chinese angelica, 15g of monkshood and 15g of szechuan lovage rhizome.
The medicament for treating the monkey trauma provided by the invention is prepared from traditional Chinese medicine materials, does not produce side effects on monkeys, and does not generate drug resistance. The medicament is prepared from borneol, dragon's blood, clematis root, salvia miltiorrhiza, salted achyranthes root, parasitic loranthus, beautiful sweetgum fruit, red paeony root, Chinese angelica, prepared common monkshood daughter root and Szechuan lovage rhizome. The dragon's blood in the medicinal materials can promote blood circulation, relieve pain, remove blood stasis, stop bleeding, heal wound and promote tissue regeneration; the clematis root, the parasitic loranthus and the beautiful sweetgum fruit have the function of dredging the channels and collaterals; notoginseng radix powder, Saviae Miltiorrhizae radix, Sal Achyranthis radix, radix Angelicae sinensis and rhizoma Ligustici Chuanxiong can promote blood circulation and remove blood stasis. The contents of the components of the medicinal materials are reasonable, and after the medicinal materials are compatible and combined with each other, the healing of the trauma wound of the monkey can be effectively promoted, and the treatment effect is obvious.
The mixture is powdery, and the powdery medicinal powder can enable the wound to better absorb the effective components of the medicament, so that the treatment effect is better.
The preparation method of the drug for treating the monkey trauma comprises the following preparation steps:
(1) weighing dragon's blood, clematis root, salvia miltiorrhiza, salted achyranthes root, parasitic loranthus, beautiful sweetgum fruit, red paeony root, Chinese angelica, prepared common monkshood daughter root and szechuan lovage rhizome according to the parts by weight, and mixing;
(2) carrying out microwave drying on the mixed medicinal materials for 20-60 minutes, and then crushing into powder to obtain mixed medicinal powder;
(3) weighing borneol according to the weight parts, crushing the borneol and mixing the crushed borneol with the mixed powder obtained in the step (2).
The using method is that 15g of the drug for treating the monkey trauma is weighed as a standard part, and 1 standard part of medicinal powder is used for each drug for treating each monkey with trauma. Applying 1 standard part of the medicinal powder to the wound of monkey, wrapping with gauze, changing the dressing once a day, and taking three days as a course of treatment, wherein the times of the course of treatment depend on the size and severity of the wound.
Example 2
The invention relates to a medicament for treating monkey trauma, which is a mixture prepared from the following Chinese medicinal raw materials in parts by weight: 2g of borneol, 13g of dragon's blood, 13g of clematis root, 13g of pseudo-ginseng powder, 13g of salvia miltiorrhiza, 13g of salted achyranthes root, 13g of parasitic loranthus, 13g of beautiful sweetgum fruit, 13g of red paeony root, 13g of Chinese angelica, 13g of monkshood and 13g of szechuan lovage rhizome.
The mixture is powder.
The preparation method and the using method of the drug for treating the monkey trauma are the same as the example 1.
Example 3
The invention relates to a medicament for treating monkey trauma, which is a mixture prepared from the following Chinese medicinal raw materials in parts by weight: 4g of borneol, 17g of dragon's blood, 17g of clematis root, 17g of pseudo-ginseng powder, 17g of salvia miltiorrhiza, 17g of salted achyranthes root, 17g of parasitic loranthus, 17g of beautiful sweetgum fruit, 15g of red paeony root, 17g of Chinese angelica, 17g of monkshood and 17g of szechuan lovage rhizome.
The mixture is powder.
The preparation method and the using method of the drug for treating the monkey trauma are the same as the example 1.
Example 4
The invention relates to a medicament for treating monkey trauma, which is a mixture prepared from the following Chinese medicinal raw materials in parts by weight: 2g of borneol, 17g of dragon's blood, 13g of clematis root, 17g of pseudo-ginseng powder, 13g of salvia miltiorrhiza, 17g of salted achyranthes root, 13g of parasitic loranthus, 17g of beautiful sweetgum fruit, 13g of red paeony root, 17g of Chinese angelica, 13g of monkshood and 17g of szechuan lovage rhizome.
The mixture is powder.
The preparation method and the using method of the drug for treating the monkey trauma are the same as the example 1.
Example 5
The invention relates to a medicament for treating monkey trauma, which is a mixture prepared from the following Chinese medicinal raw materials in parts by weight: 4g of borneol, 13g of dragon's blood, 17g of clematis root, 13g of pseudo-ginseng powder, 17g of salvia miltiorrhiza, 13g of salted achyranthes root, 17g of parasitic loranthus, 13g of beautiful sweetgum fruit, 17g of red paeony root, 13g of Chinese angelica, 17g of monkshood and 13g of szechuan lovage rhizome.
The mixture is powder.
The preparation method and the using method of the drug for treating the monkey trauma are the same as the example 1.
Example 6
The invention relates to a medicament for treating monkey trauma, which is a mixture prepared from the following Chinese medicinal raw materials in parts by weight: 2g of borneol, 14g of dragon's blood, 16g of clematis root, 14g of pseudo-ginseng powder, 16g of salvia miltiorrhiza, 14g of salted achyranthes root, 16g of parasitic loranthus, 14g of beautiful sweetgum fruit, 16g of red paeony root, 14g of Chinese angelica, 16g of monkshood and 14g of szechuan lovage rhizome.
The mixture is powder.
The preparation method and the using method of the drug for treating the monkey trauma are the same as the example 1.
The following experimental subjects were monkeys raised in the Guidong primate raising base.
Test example 1
6 and 3 days in 2019, when a monkey nail with 2 years and 5 months in age is fed by a breeder in the morning, the fact that the area from the arm to the outer side of the palm is large is found, the wound area is about 15-18 cm, bones are seen in the wound of the palm, as shown in figure 1, 2 standard parts of the medicine is applied to the wound of the monkey nail immediately, the monkey nail is bound with gauze once a day, after 5 days of continuous application, the wound condition of the monkey nail is observed, the wound is found to be scabbed and has no suppuration phenomenon, the medicine is stopped and the gauze is taken away after 2 days of continuous application, the monkey nail has no uncomfortable symptoms in the medicine application process, the state is normal, the scab falls off after 10 days, and the healing condition of the wound is good, as shown in figures 2 and 3.
Test example 2
After 7 and 21 days in 2018, a monkey B with the age of 1 year and 9 months is fed by a breeder in the evening, the arm of the monkey B is scratched, the wound grows to be about 3 cm and is 0.5 cm deep, 1 standard part of the medicament is immediately applied to the affected part of the monkey B, the affected part is bound with gauze once a day, after the monkey B is continuously applied for 3 days, the wound condition of the monkey B is observed, the affected part is found to be scarred and has no suppuration phenomenon, the scab formed after 4 days is fallen off, the healing condition of the affected part is good, the monkey has no uncomfortable symptoms in the medication process, and the state is normal.
Test example 3
After the monkey patient is fed by a breeder in the morning for 11 days in 2018 and 11 months, the outer side of the lower leg of the monkey patient is scratched, the wound is about 3 cm long and about 0.4 cm deep, and the wound is oozed by blood, 1 standard part of the medicament is immediately applied to the affected part of the monkey patient, the affected part is bound with gauze once a day, the wound is stopped when the breeder feeds the monkey patient in the evening of the day, the wound condition of the monkey patient is observed after continuous medication for 3 days, the affected part is found to be scarred and has no suppuration phenomenon, the scab phenomenon after 3 days is fallen, the healing condition of the affected part is good, the monkey patient has no uncomfortable symptoms in the medication process, and the condition is normal.
Test example 4
After 7-11 days in 2020, monkeys aged 2 years and 4 months are fed, a breeder in the morning discovers that a large-area wound appears on the upper side of soles and the ankles, the wound area is about 10-12 cm, 2 standard parts of the medicine is immediately applied to the wound position of the monkeys, the monkeys are wrapped with gauze once a day, after the monkeys are continuously applied for 4 days, the wound condition of the monkeys is observed, the affected parts are found to be scab and free of suppuration, the medicine is stopped and the gauze is taken away after the medicine is applied for 1 day, the scab formed after 7 days falls off, the healing condition of the affected parts is good, no uncomfortable symptoms appear in the medicine application process, and the state is normal.
The above description is only exemplary of the invention, and any modification, equivalent replacement, and improvement made within the spirit and scope of the present invention should be considered within the scope of the present invention.
Claims (4)
1. The drug for treating the trauma of the monkey is characterized by being a mixture prepared from the following traditional Chinese medicine raw materials in parts by weight: 2-4 g of borneol, 13-17 g of dragon's blood, 13-17 g of clematis root, 13-17 g of pseudo-ginseng powder, 13-17 g of salvia miltiorrhiza, 13-17 g of achyranthes bidentata, 13-17 g of loranthus parasiticus, 13-17 g of beautiful sweetgum fruit, 13-17 g of red paeony root, 13-17 g of Chinese angelica, 13-17 g of monkshood and 13-17 g of szechuan lovage rhizome.
2. The medicament for treating monkey trauma according to claim 1, which is a mixture prepared from the following Chinese medicinal raw materials in parts by weight: 3g of borneol, 15g of dragon's blood, 15g of clematis root, 15g of pseudo-ginseng powder, 15g of salvia miltiorrhiza, 15g of salted achyranthes root, 15g of parasitic loranthus, 15g of beautiful sweetgum fruit, 15g of red paeony root, 15g of Chinese angelica, 15g of monkshood and 15g of szechuan lovage rhizome.
3. The agent for treating trauma in monkeys according to claim 1 or 2, wherein the mixture is in powder form.
4. The process for preparing a pharmaceutical agent for treating trauma in monkeys according to claim 1, comprising the steps of:
(1) weighing dragon's blood, clematis root, salvia miltiorrhiza, salted achyranthes root, parasitic loranthus, beautiful sweetgum fruit, red paeony root, Chinese angelica, prepared common monkshood daughter root and szechuan lovage rhizome according to the parts by weight, and mixing;
(2) carrying out microwave drying on the mixed medicinal materials for 20-60 minutes, and then crushing into powder to obtain mixed medicinal powder;
(3) weighing borneol according to the weight parts, crushing the borneol and mixing the crushed borneol with the mixed powder obtained in the step (2).
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