CN113853387A - 能结合胸腺基质淋巴细胞生成素的抗体及其应用 - Google Patents
能结合胸腺基质淋巴细胞生成素的抗体及其应用 Download PDFInfo
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Abstract
能结合胸腺基质淋巴细胞生成素的抗体及其应用。一种抗TSLP抗体，包含所述抗TSLP抗体轻链和重链可变区的鼠源抗体、嵌合抗体、人源化抗体及其抗原结合片段，或其可药用盐或溶剂化合物，以及其作为治疗哮喘药物的用途，尤其在制备用于治疗TSLP阳性疾病或病症的药物中的用途。
Description
PCT国内申请，说明书已公开。
Claims (17)
- PCT国内申请，权利要求书已公开。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310221482.2A CN116751295A (zh) | 2019-06-04 | 2020-06-03 | 能结合胸腺基质淋巴细胞生成素的抗体及其应用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2019104805799 | 2019-06-04 | ||
| CN201910480579 | 2019-06-04 | ||
| PCT/CN2020/094154 WO2020244544A1 (zh) | 2019-06-04 | 2020-06-03 | 能结合胸腺基质淋巴细胞生成素的抗体及其应用 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310221482.2A Division CN116751295A (zh) | 2019-06-04 | 2020-06-03 | 能结合胸腺基质淋巴细胞生成素的抗体及其应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN113853387A true CN113853387A (zh) | 2021-12-28 |
| CN113853387B CN113853387B (zh) | 2023-04-04 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202080036757.XA Active CN113853387B (zh) | 2019-06-04 | 2020-06-03 | 能结合胸腺基质淋巴细胞生成素的抗体及其应用 |
| CN202310221482.2A Pending CN116751295A (zh) | 2019-06-04 | 2020-06-03 | 能结合胸腺基质淋巴细胞生成素的抗体及其应用 |
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| CN202310221482.2A Pending CN116751295A (zh) | 2019-06-04 | 2020-06-03 | 能结合胸腺基质淋巴细胞生成素的抗体及其应用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20220340654A1 (zh) |
| EP (1) | EP3981788A4 (zh) |
| JP (1) | JP2022535808A (zh) |
| KR (1) | KR20220016897A (zh) |
| CN (2) | CN113853387B (zh) |
| AU (1) | AU2020286889A1 (zh) |
| BR (1) | BR112021024112A2 (zh) |
| CA (1) | CA3142545A1 (zh) |
| MX (1) | MX2021014804A (zh) |
| TW (1) | TW202110882A (zh) |
| WO (1) | WO2020244544A1 (zh) |
| ZA (1) | ZA202110236B (zh) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2023006596A (es) * | 2020-12-03 | 2023-06-19 | Jiangsu Hengrui Pharmaceuticals Co Ltd | Composicion farmaceutica de anticuerpo anti-tslp y uso de la misma. |
| MX2023009971A (es) * | 2021-03-03 | 2023-09-05 | Chia Tai Tianqing Pharmaceutical Group Co Ltd | Composicion farmaceutica que contiene anticuerpo anti-tslp. |
| CN115433275A (zh) * | 2021-06-02 | 2022-12-06 | 启愈生物技术(上海)有限公司 | 抗胸腺基质淋巴细胞生成素（tslp）抗体及其用途 |
| CN113069543B (zh) * | 2021-06-07 | 2021-08-06 | 迈威(上海)生物科技股份有限公司 | 包含抗胸腺基质淋巴细胞生成素的单克隆抗体的液体组合物 |
| CN113683694B (zh) * | 2021-09-03 | 2022-05-13 | 江苏荃信生物医药股份有限公司 | 一种抗人tslp单克隆抗体及其应用 |
| CN117209603B (zh) * | 2021-12-02 | 2024-02-27 | 北京东方百泰生物科技股份有限公司 | 一种抗tslp的单克隆抗体、其抗原结合片段及其应用 |
| US20240034780A1 (en) * | 2022-07-22 | 2024-02-01 | Flagship Pioneering Innovations Vi, Llc | Antigen Binding Molecules Targeting Thymic Stromal Lymphopoietin (TSLP) |
| WO2024146630A1 (zh) * | 2023-01-06 | 2024-07-11 | 江苏恒瑞医药股份有限公司 | 一种tslp抗体治疗哮喘的方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101605814A (zh) * | 2006-12-14 | 2009-12-16 | 先灵公司 | 经工程改造的抗tslp抗体 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| GB0603683D0 (en) * | 2006-02-23 | 2006-04-05 | Novartis Ag | Organic compounds |
| KR20100034015A (ko) | 2007-06-20 | 2010-03-31 | 아이알엠 엘엘씨 | 알레르기 질환 치료를 위한 방법 및 조성물 |
| US7982016B2 (en) | 2007-09-10 | 2011-07-19 | Amgen Inc. | Antigen binding proteins capable of binding thymic stromal lymphopoietin |
| US8637019B2 (en) | 2009-11-04 | 2014-01-28 | Merck Sharp & Dohme Corp. | Engineered anti-TSLP antibody |
| US20140227250A1 (en) * | 2012-08-23 | 2014-08-14 | Merck Sharp & Dohme Corp. | Stable formulations of antibodies to tslp |
| TW201643179A (zh) | 2015-03-11 | 2016-12-16 | 葛蘭素史克智慧財產發展有限公司 | Ｔｓｌｐ結合蛋白 |
| KR20180021875A (ko) | 2015-06-30 | 2018-03-05 | 베링거 인겔하임 인터내셔날 게엠베하 | 다중특이적 결합 단백질 |
| JOP20190243A1 (ar) * | 2017-04-12 | 2019-10-13 | Medimmune Llc | علاج الربو بجسم مضاد لـ tslp |
| CN109206514B (zh) * | 2017-07-03 | 2019-10-08 | 拜西欧斯（北京）生物技术有限公司 | Tslp单克隆抗体及其制备方法和应用 |
-
2020
- 2020-06-03 WO PCT/CN2020/094154 patent/WO2020244544A1/zh unknown
- 2020-06-03 MX MX2021014804A patent/MX2021014804A/es unknown
- 2020-06-03 KR KR1020217042510A patent/KR20220016897A/ko unknown
- 2020-06-03 BR BR112021024112A patent/BR112021024112A2/pt unknown
- 2020-06-03 AU AU2020286889A patent/AU2020286889A1/en active Pending
- 2020-06-03 TW TW109118623A patent/TW202110882A/zh unknown
- 2020-06-03 CN CN202080036757.XA patent/CN113853387B/zh active Active
- 2020-06-03 CA CA3142545A patent/CA3142545A1/en active Pending
- 2020-06-03 JP JP2021571599A patent/JP2022535808A/ja active Pending
- 2020-06-03 EP EP20819147.8A patent/EP3981788A4/en active Pending
- 2020-06-03 CN CN202310221482.2A patent/CN116751295A/zh active Pending
- 2020-06-03 US US17/615,970 patent/US20220340654A1/en active Pending
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2021
- 2021-12-09 ZA ZA2021/10236A patent/ZA202110236B/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101605814A (zh) * | 2006-12-14 | 2009-12-16 | 先灵公司 | 经工程改造的抗tslp抗体 |
Also Published As
| Publication number | Publication date |
|---|---|
| TW202110882A (zh) | 2021-03-16 |
| AU2020286889A1 (en) | 2022-01-20 |
| EP3981788A4 (en) | 2023-03-22 |
| CA3142545A1 (en) | 2020-12-10 |
| CN113853387B (zh) | 2023-04-04 |
| MX2021014804A (es) | 2022-01-18 |
| EP3981788A1 (en) | 2022-04-13 |
| CN116751295A (zh) | 2023-09-15 |
| WO2020244544A1 (zh) | 2020-12-10 |
| ZA202110236B (en) | 2022-08-31 |
| KR20220016897A (ko) | 2022-02-10 |
| BR112021024112A2 (pt) | 2022-03-22 |
| JP2022535808A (ja) | 2022-08-10 |
| US20220340654A1 (en) | 2022-10-27 |
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