CN113797262A

CN113797262A - Composition for relaxing muscles and tendons and dredging collaterals, preparation method and application thereof

Info

Publication number: CN113797262A
Application number: CN202111034461.7A
Authority: CN
Inventors: 吴军尚
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-09-03
Filing date: 2021-09-03
Publication date: 2021-12-17

Abstract

The invention provides a composition for relaxing muscles and tendons and dredging collaterals, a preparation method and application thereof, and relates to the technical field of traditional Chinese medicine formulas. The composition for relaxing muscles and tendons and dredging collaterals comprises the following raw materials of common clubmoss herb, garden balsam stem, herba siegesbeckiae, suberect spatholobus stem, Chinese starjasmine stem, honeysuckle stem, loofah sponge, eucommia bark, cassia bark, dahurian angelica root, clove, fennel, costustoot, frankincense, Chinese eaglewood, rhizoma atractylodis, incised notopterygium rhizome, doubleteeth pubescent angelica root, honeycomb and oriental wormwood; the composition has effects of relaxing muscles and tendons, dredging collaterals, dispelling pathogenic wind, removing dampness, strengthening tendons and bones, effectively improving muscle and bone strain and rheumatism arthralgia, and enhancing constitution of patients. The invention also provides a preparation method of the composition for relaxing muscles and tendons and dredging collaterals; the preparation method is simple and convenient to operate, has low operation difficulty, is convenient to prepare, and can fully extract beneficial components in the medicinal materials so as to avoid raw material waste.

Description

Composition for relaxing muscles and tendons and dredging collaterals, preparation method and application thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicine formulas, and particularly relates to a composition for relaxing muscles and tendons and dredging collaterals, a preparation method and application thereof.

Background

Rheumatism is a group of diseases mainly attacking joints, bones, muscles, blood vessels and related soft tissues or connective tissues, and most of them are autoimmune diseases. The disease is usually more hidden and slower, the disease course is longer, and most of the diseases have hereditary tendency. In a broad sense, diseases causing pain in bones and joints and muscles are classified as rheumatism. The common symptoms of rheumatism are that the joint of a patient can be painful in rainy days or wet, which not only affects the health of the joint, but also causes troubles to the patient. Currently, rheumatism is generally treated by drug therapy and surgery, the surgery therapy is dangerous and high in price, but the drug therapy is easy to relapse and poor in curative effect.

Disclosure of Invention

The invention aims to provide a composition for relaxing muscles and tendons and dredging collaterals, which can relax muscles and tendons and dredging collaterals, dispel wind and remove dampness, strengthen tendons and bones, effectively improve symptoms such as muscle and bone strain and rheumatism arthralgia and enhance the physique of patients.

The second purpose of the invention is to provide the application of the composition for relaxing muscles and tendons and dredging collaterals in preparing the medicines for treating rheumatism and soreness and pain of waist and knees.

The third purpose of the invention is to provide a preparation method of the composition for relaxing muscles and tendons and dredging collaterals, the preparation method is simple and convenient to operate, the operation difficulty is low, the preparation is convenient, and beneficial ingredients in medicinal materials can be fully extracted, so that the waste of raw materials is avoided.

The technical problem to be solved by the invention is realized by adopting the following technical scheme.

On one hand, the embodiment of the application provides a composition for relaxing muscles and tendons and removing obstruction in channels, which comprises the following raw materials, by weight, 45-55 parts of lycopodium clavatum, 45-55 parts of garden balsam stem, 45-55 parts of herba siegesbeckiae, 20-30 parts of caulis spatholobi, 20-30 parts of Chinese starjasmine stem, 20-30 parts of honeysuckle stem, 20-30 parts of loofah sponge, 20-30 parts of eucommia bark, 20-30 parts of cinnamon, 20-30 parts of angelica dahurica, 20-30 parts of clove, 20-30 parts of fennel, 20-30 parts of elecampane, 70-80 parts of frankincense, 10-20 parts of agilawood, 20-30 parts of rhizoma atractylodis, 20-30 parts of notopterygium root, 20-30 parts of radix angelicae pubescentis, 15-25 parts of honeycomb and 25-35 parts of oriental wormwood.

The medicinal materials are combined in a reasonable monarch, minister, assistant and guide relationship, wherein monarch medicines are lycopodium clavatum and garden balsam stems, and the lycopodium clavatum and the garden balsam stems have mild medicine properties and mainly have the effects of activating blood, enriching blood, strengthening bones, dispelling wind and removing dampness, so that human body tendons and collaterals are more robust and powerful; the ministerial drugs are herba siegesbeckiae, caulis spatholobi, Chinese starjasmine stem, honeysuckle stem, eucommia bark, herba artemisiae scopariae, cinnamon, angelica dahurica, clove, fennel, elecampane, frankincense, agilawood, rhizoma atractylodis and radix angelicae pubescentis, wherein the herba artemisiae scopariae, the herba siegesbeckiae, the Chinese starjasmine stem and the honeysuckle stem are cold in nature, and the rest drugs are yin in nature and mutually matched to harmonize the drug properties of various warm drugs in the ministerial drugs, so that the drug properties of the whole composition are more mild, and the composition is convenient to take. The adjuvant drugs are the nidus vespae and the loofah sponge, the nidus vespae and the loofah sponge are mild in drug property, the drug properties of the ministerial drugs and the monarch drugs are harmonized, and the drug properties of the ministerial drugs and the monarch drugs are cooperated, so that the monarch drugs and the ministerial drugs are assisted and play a role in regulating qi and blood, and the drug properties of the prepared composition tend to be mild by combining yin and yang of the drug properties of the medicinal materials, so that the composition is convenient for human body to take and absorb.

On the other hand, the embodiment of the application also provides a preparation method of the composition for relaxing muscles and tendons and dredging collaterals, which comprises the following steps of grinding and sieving lycopodium clavatum, garden balsam stem, herba siegesbeckiae, caulis spatholobi, Chinese starjasmine stem, honeysuckle stem, loofah sponge, eucommia bark, cinnamon, radix angelicae, clove, fennel, costus root, frankincense, agilawood, rhizoma atractylodis, notopterygium root, radix angelicae pubescentis, honeycomb and oriental wormwood to obtain powder, and sequentially extracting, filtering, concentrating and drying the powder to obtain the composition for relaxing muscles and tendons and dredging collaterals. The method extracts the beneficial components in the medicinal materials fully by extracting, filtering and concentrating the powder, thereby improving the drug property and curative effect of the prepared composition.

Compared with the prior art, the embodiment of the invention has at least the following advantages or beneficial effects:

the embodiment of the invention provides a composition for relaxing muscles and tendons and dredging collaterals, which is prepared by matching reasonable monarch, minister, assistant and guide relations, and the composition is prepared by matching a cold drug, a warm drug and a mild drug in a reasonable matching relation, so that the drugs can be cooperated to play a role, the drug properties of beneficial components in the drugs can be fully played, the drug properties of the drugs can be enabled to be mild, the composition is convenient for a patient to use, the drug properties can be conveniently absorbed by the patient, and the side effect of the composition is reduced.

The embodiment of the invention also provides a preparation method of the composition for relaxing muscles and tendons and dredging collaterals, the method is simple and convenient, is easy to operate, is convenient to popularize and implement, and greatly reduces the operation difficulty of operators; the method extracts the beneficial components from the medicinal materials by extracting, filtering and concentrating the powder, thereby improving the drug property and curative effect of the prepared composition.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.

It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present invention will be described in detail below with reference to specific examples.

On one hand, the embodiment of the application provides a composition for relaxing muscles and tendons and removing obstruction in channels, which comprises the following raw materials, by weight, 45-55 parts of lycopodium clavatum, 45-55 parts of garden balsam stem, 45-55 parts of herba siegesbeckiae, 20-30 parts of caulis spatholobi, 20-30 parts of Chinese starjasmine stem, 20-30 parts of honeysuckle stem, 20-30 parts of loofah sponge, 20-30 parts of eucommia bark, 20-30 parts of cinnamon, 20-30 parts of angelica dahurica, 20-30 parts of clove, 20-30 parts of fennel, 20-30 parts of elecampane, 70-80 parts of frankincense, 10-20 parts of agilawood, 20-30 parts of rhizoma atractylodis, 20-30 parts of notopterygium root, 20-30 parts of radix angelicae pubescentis, 15-25 parts of honeycomb and 25-35 parts of oriental wormwood. Herba Lycopodii is dry whole plant of Lycopodium clavatum of Lycopodiaceae, and is called Lycopodium clavatum, herba Lespedezae Bicoloris and Leontopodium Lepidioides, etc., has bitter and slightly pungent taste, warm property, and effects of invigorating liver, spleen and kidney channels, dispelling pathogenic wind, removing dampness, relieving rigidity of muscles, activating collaterals, and treating symptoms such as joint pain, difficulty in flexion and extension, etc.; the garden balsam stem is the whole herb of the leaves of the plant of the genus Eleutherococcus of the family Euphorbiaceae, namely the pearl garden balsam stem, the bamboo fork, the Gelidium japonicum and the Chinese holly bark grass, has pungent taste and warm property, enters liver and kidney channels, has the effects of dispelling wind and removing dampness, relaxing muscles and tendons and activating blood circulation, dissipating blood stasis and reducing swelling, detoxifying and relieving pain, and is mainly used for treating symptoms such as rheumatic arthralgia, contracture of muscles and bones, waist sprain, paralysis and the like; the herba Siegesbeckiae is aerial part of herba Siegesbeckiae, herba siegesbeckiae Pubescens or herba siegesbeckiae Makino of Compositae, has pungent, bitter and cold properties, and can enter liver and kidney channels, has effects of dispelling rheumatism, strengthening tendons and bones, clearing heat and detoxicating, and can be used for treating rheumatalgia, hemiplegia caused by apoplexy, etc.; caulis Spatholobi is dry rattan of Leguminosae plant Callosa Millettii, is bitter and sweet in taste, warm in nature, and enters liver and kidney channels, has effects of promoting blood circulation, replenishing blood, regulating menstruation, relieving pain, relaxing muscles and tendons, and activating collaterals, and can be used for treating rheumatalgia, numbness and paralysis; caulis trachelospermi, namely jasmine, stone dace, Mingshi stone, rubus chingii, pearl, Yunnan Dan, red-pair leaf kidney and white-flower vine, are the leaf-carrying rattan of trachelospermi caulis of apocynaceae, are slightly cold in nature and bitter in taste, enter heart, liver and kidney channels, have the effects of dredging collaterals and relieving pain and the like, and are mainly used for treating symptoms such as rheumatic arthralgia, soreness of waist and knees, spasm of muscles and tendons, traumatic injury and the like; caulis Lonicerae, the dry rattan of Lonicera japonica of Caprifoliaceae, is called caulis fici Pumilae, caulis Fibraureae, caulis Stephaniae Japonicae, etc., has sweet taste, cold nature, heart and lung meridian entered, has effects of clearing heat and dredging collaterals, and is mainly used for treating symptoms such as arthralgia and myalgia; the retinervus Luffae fructus is bundle of vascular of dried mature fruit of Cucurbitaceae plant retinervus Luffae fructus, also called retinervus Luffae fructus, exocarpium melo, etc., has sweet taste, neutral nature, and effects of entering stomach, lung, and liver meridian, has effects of dispelling pathogenic wind, dredging collaterals, promoting blood circulation, and can be used for treating symptoms such as rheumatalgia and spasm; cortex Eucommiae is bark of cortex Eucommiae of Eucommiaceae, named as JIA XIAN, and Eucommiae cortex, is sweet and slightly pungent, warm in nature, enters liver and kidney channels, has effects of strengthening tendons and bones, and is mainly used for treating soreness of waist and back, and debility of feet and knees; the cinnamon is dry bark of cinnamon of Lauraceae, is called as cinnamon, cinnamon and the like, is pungent, sweet and hot in nature, enters kidney, spleen, heart and liver channels, has the effects of tonifying fire and supporting yang, guiding fire to return to original, dispelling cold and relieving pain, and warming and dredging channels and collaterals, and is mainly used for treating symptoms such as cold pain of waist and knees; the dried root of Angelica dahurica or Angelica dahurica of Angelica Umbelliferae, with special flavor, pungent taste, warm nature, and entering lung, spleen, stomach channel, has effects of dispelling pathogenic wind and relieving pain, and is mainly used for treating rheumatalgia and other symptoms; flos Caryophylli is the dried bud of flos Caryophylli of Myrtaceae, has pungent taste and warm nature, and has effects of dispelling pathogenic wind and relieving pain, and can be used for treating rheumatalgia; the fructus Foeniculi is the fruit of Foeniculum vulgare of Umbelliferae, is called fructus Foeniculi, has pungent taste and warm nature, has effects of dispelling cold and relieving pain, and can be used for treating cold hand and foot, waist and abdomen pain, etc.; radix aucklandiae, it is the dry root of radix aucklandiae of Compositae, another name is radix aucklandiae etc., pungent, bitter, warm in nature, enter spleen, stomach, large intestine, triple warmer, gallbladder channel, etc., it has effects of promoting qi circulation and relieving pain, etc., it is the symptom such as pain of waist and legs mainly; olibanum is resin exuded from bark of Boswellia carterii of Burseraceae and plants of the same genus, and is called Tianzexiang, etc., has pungent, bitter and warm properties, and has effects of activating qi-flowing, relieving pain, strengthening tendons and bones, and is mainly used for treating rheumatalgia, spasm of tendons and vessels, traumatic injury, etc.; the lignum Aquilariae Resinatum is wood containing resin of Aquilaria sinensis of Rutaceae, has pungent, bitter, and mild properties, and has effects of activating qi-flowing and relieving pain, and can be used for treating chest and abdominal distention and pain; the rhizoma Atractylodis is dried rhizome of Atractylodes lancea or Atractylodes chinensis of Compositae, is named as herba Cirsii Japonici, is pungent, bitter, and warm in nature, and has effects of invigorating spleen and eliminating dampness, dispelling pathogenic wind and dispelling cold, and can be used for treating rheumatalgia; notopterygii rhizoma is dry root of Notopterygii rhizoma of Umbelliferae, is named as Notopterygii rhizoma, is pungent and bitter, has warm nature, enters bladder and kidney channels, has effects of dispelling pathogenic wind and removing dampness, relieving pain and dispelling cold, and is mainly used for treating anemofrigid-damp arthralgia, neck rigidity, and articulation pain; radix Angelicae Pubescentis, is the dried root of Angelica gigas nakai of Umbelliferae, is also called Changsheng grass, etc., is pungent, bitter, slightly warm in nature, enters kidney and bladder channels, has the effects of dispelling pathogenic wind, removing dampness, relieving arthralgia, relieving pain, etc., and is mainly used for treating wind-cold-dampness arthralgia, waist and knee pain, etc.; the nidus Vespae is nest of Vespidae insect Vespa mandala, Japanese Petasites Japonici or Wasp Ex Freyn, has sweet taste, neutral nature, and stomach meridian tropism, has effects of dispelling pathogenic wind and relieving pain, and can be used for treating rheumatalgia and other symptoms; herba Artemisiae Scopariae is dry aerial part of herba Artemisiae Scopariae or herba Artemisiae Scopariae of Compositae, and is called herba Aristolochiae, etc., has slightly bitter and pungent taste and cold nature, and has effects of dispelling pathogenic wind and removing dampness, etc., and can be used for treating rheumatalgia, etc.

In some embodiments of the present invention, the tendon relaxing and collateral dredging composition further comprises 1400-1600 parts of artemisia argyi. The folium artemisiae argyi is dry leaves of folium artemisiae argyi of a Compositae plant, is called folium artemisiae argyi and folium artemisiae argyi, is pungent, bitter and warm in nature, enters liver, spleen and kidney channels, has the effects of warming channels to stop bleeding, dispelling cold to stop pain and the like, is mainly used for treating symptoms such as irregular channel, skin itch and the like. The moxibustion mechanism is similar to that of acupuncture and moxibustion, and has complementary therapeutic effects with acupuncture and moxibustion. Has the advantages of simple operation, low cost, obvious effect and the like. Compared with the effect achieved by directly taking the composition, the effect is better, and the curative effect of the composition is further improved.

In some embodiments of the present invention, the artemisia leaf is artemisia scoparia and the artemisia capillaris is dried artemisia capillaris. The south-yang moxa is larger in planting scale than other areas and lower in cost when used as a raw material, and is better in growth vigor than moxa in other areas and higher in quality, so that the curative effect of a part of the composition can be improved. The dried mushroom contains less water, so that the low concentration of beneficial ingredients in the composition caused by excessive water is avoided.

In some embodiments of the present invention, the tendon relaxing and collateral dredging composition comprises, by weight, 50 parts of lycopodium clavatum, 50 parts of speranskia herb, 50 parts of herba siegesbeckiae, 25 parts of caulis spatholobi, 25 parts of Chinese starjasmine stem, 25 parts of honeysuckle stem, 25 parts of loofah sponge, 25 parts of eucommia bark, 25 parts of cinnamon, 25 parts of radix angelicae, 25 parts of clove, 25 parts of fennel, 25 parts of costus root, 75 parts of frankincense, 15 parts of agilawood, 25 parts of rhizoma atractylodis, 25 parts of notopterygium root, 25 parts of radix angelicae pubescentis, 20 parts of honeycomb, 30 parts of tarragon and 1500 parts of folium artemisiae argyi. The proportioning scheme is the preferable proportioning scheme, and the composition prepared by the proportioning scheme not only has mild medicine property, but also has better curative effect.

On the other hand, the embodiment of the invention also provides a preparation method of the composition for relaxing muscles and tendons and dredging collaterals, which comprises the following steps of grinding and sieving lycopodium clavatum, garden balsam stem, herba siegesbeckiae, caulis spatholobi, Chinese starjasmine stem, honeysuckle stem, loofah sponge, eucommia bark, cinnamon, radix angelicae, clove, fennel, elecampane, frankincense, agilawood, rhizoma atractylodis, notopterygium root, radix angelicae pubescentis, honeycomb and artemisia capillaris to obtain powder, and sequentially extracting, filtering, concentrating and drying the powder to obtain the composition for relaxing muscles and tendons and dredging collaterals. The method extracts the beneficial components in the medicinal materials fully by extracting, filtering and concentrating the powder, thereby improving the drug property and curative effect of the prepared composition.

In some embodiments of the present invention, the drying further includes a final treatment, the final treatment includes the following steps, the drying obtains the extract, the extract is wrapped by the folium artemisiae argyi and rolled into strips, and the composition for relaxing muscles and tendons and removing obstruction in channels is obtained. The composition is rolled into moxa stick and the medicinal effect of the composition is exerted in a moxibustion way, so that the medicinal effect of the composition is convenient to absorb.

In some embodiments of the present invention, the drying and the final treatment further comprise a pretreatment, wherein the pretreatment comprises the steps of pulverizing the mugwort leaves and preparing the mugwort floss. Moxa wool is a soft and fine cotton-like substance obtained by repeatedly drying folium artemisiae argyi in the sun, pestling, beating and crushing, and screening out impurities and dust. Moxa wool is a raw material for making moxa sticks and is also a main material used in moxibustion.

In some embodiments of the invention, the extraction is alcohol extraction, the temperature of the alcohol extraction is 50-80 ℃, and the time of the alcohol extraction is 5-8 h. The beneficial components in the medicinal materials are extracted by alcohol extraction, and impurities in the medicinal materials are removed, so that the purity of the composition is improved.

In some embodiments of the invention, the above-described concentration has a relative density of 1.15 to 1.22. The relative density interval can ensure that the prepared composition is more stable and has better drug effect.

The features and properties of the present invention are described in further detail below with reference to examples.

Example 1

The embodiment provides a composition for relaxing muscles and tendons and dredging collaterals, which comprises 45g of lycopodium clavatum, 45g of garden balsam stem, 45g of herba siegesbeckiae, 20g of caulis spatholobi, 20g of Chinese starjasmine stem, 20g of honeysuckle stem, 20g of loofah sponge, 20g of eucommia bark, 20g of cinnamon, 20g of radix angelicae, 20g of clove, 20g of fennel, 20g of elecampane, 70g of frankincense, 10g of agilawood, 20g of rhizoma atractylodis, 20g of notopterygium root, 20g of radix angelicae pubescentis, 15g of honeycomb, 25g of dried mushroom and 1400g of south-yang moxa.

The embodiment also provides a preparation method of the composition for relaxing muscles and tendons and dredging collaterals, which comprises the following steps of grinding and sieving lycopodium clavatum, garden balsam stem, herba siegesbeckiae, caulis spatholobi, Chinese starjasmine stem, honeysuckle stem, loofah sponge, eucommia bark, cinnamon, radix angelicae, clove, fennel, elecampane, frankincense, agilawood, rhizoma atractylodis, notopterygium root, radix angelicae pubescentis, honeycomb and artemisia capillaris to obtain powder, carrying out alcohol extraction on the powder at 50 ℃ for 5 hours, filtering to remove filtrate, concentrating the filtrate to a relative density of 1.15, drying to obtain an extract, crushing and beating the artemisia anomala into moxa, wrapping the extract in the moxa and rolling into strips to obtain the composition for relaxing muscles and tendons and dredging collaterals.

Example 2

The embodiment provides a composition for relaxing muscles and tendons and dredging collaterals, which comprises 45g of lycopodium clavatum, 55g of garden balsam stem, 55g of herba siegesbeckiae, 30g of caulis spatholobi, 30g of Chinese starjasmine stem, 30g of honeysuckle stem, 30g of loofah sponge, 30g of eucommia bark, 30g of cinnamon, 30g of radix angelicae, 30g of clove, 30g of fennel, 30g of elecampane, 80g of frankincense, 20g of agilawood, 30g of rhizoma atractylodis, 30g of notopterygium root, 30g of radix angelicae pubescentis, 25g of honeycomb, 35g of dried mushroom and 1600g of south-yang moxa.

The embodiment also provides a preparation method of the composition for relaxing muscles and tendons and dredging collaterals, which comprises the following steps of grinding and sieving lycopodium clavatum, garden balsam stem, herba siegesbeckiae, caulis spatholobi, Chinese starjasmine stem, honeysuckle stem, loofah sponge, eucommia bark, cinnamon, radix angelicae, clove, fennel, elecampane, frankincense, agilawood, rhizoma atractylodis, notopterygium root, radix angelicae pubescentis, honeycomb and artemisia capillaris to obtain powder, carrying out alcohol extraction on the powder at 80 ℃ for 8 hours, filtering to remove filtrate, concentrating the filtrate to a relative density of 1.22, drying to obtain an extract, crushing and beating the artemisia anomala into moxa, wrapping the extract in the moxa and rolling into strips to obtain the composition for relaxing muscles and tendons and dredging collaterals.

Example 3

The embodiment provides a composition for relaxing muscles and tendons and dredging collaterals, which comprises 50g of lycopodium clavatum, 50g of garden balsam stem, 50g of herba siegesbeckiae, 25g of caulis spatholobi, 25g of Chinese starjasmine stem, 25g of honeysuckle stem, 25g of loofah sponge, 25g of eucommia bark, 25g of cinnamon, 25g of radix angelicae, 25g of clove, 25g of fennel, 25g of radix aucklandiae, 75g of frankincense, 15g of agilawood, 25g of rhizoma atractylodis, 25g of notopterygium root, 25g of radix angelicae pubescentis, 20g of honeycomb, 30g of dried mushroom and 1500g of south-yang moxa.

The embodiment also provides a preparation method of the composition for relaxing muscles and tendons and dredging collaterals, which comprises the following steps of grinding and sieving lycopodium clavatum, garden balsam stem, herba siegesbeckiae, caulis spatholobi, Chinese starjasmine stem, honeysuckle stem, loofah sponge, eucommia bark, cinnamon, radix angelicae, clove, fennel, elecampane, frankincense, agilawood, rhizoma atractylodis, notopterygium root, radix angelicae pubescentis, honeycomb and artemisia capillaris to obtain powder, carrying out alcohol extraction on the powder at 65 ℃ for 6.5 hours, filtering to remove filtrate, concentrating the filtrate to a relative density of 1.18, drying to obtain an extract, crushing and beating the artemisia anomala into artemisia wool, wrapping the extract in the artemisia wool and rolling into strips to obtain the composition for relaxing muscles and tendons and dredging collaterals.

Example 4

The embodiment provides a composition for relaxing muscles and tendons and dredging collaterals, which comprises the following raw materials of 48g of lycopodium clavatum, 48g of garden balsam stem, 48g of herba siegesbeckiae, 23g of caulis spatholobi, 23g of Chinese starjasmine stem, 23g of honeysuckle stem, 23g of loofah sponge, 23g of eucommia bark, 23g of cinnamon, 22g of radix angelicae, 23g of clove, 22g of fennel, 22g of radix aucklandiae, 73g of frankincense, 13g of agilawood, 23g of rhizoma atractylodis, 23g of notopterygium root, 22g of radix angelicae pubescentis, 18g of honeycomb, 28g of dried mushroom and 1480g of south-yang moxa.

The embodiment also provides a preparation method of the composition for relaxing muscles and tendons and dredging collaterals, which comprises the following steps of grinding and sieving lycopodium clavatum, garden balsam stem, herba siegesbeckiae, caulis spatholobi, Chinese starjasmine stem, honeysuckle stem, loofah sponge, eucommia bark, cinnamon, radix angelicae, clove, fennel, elecampane, frankincense, agilawood, rhizoma atractylodis, notopterygium root, radix angelicae pubescentis, honeycomb and artemisia capillaris to obtain powder, carrying out alcohol extraction on the powder at 60 ℃ for 6 hours, filtering to remove filtrate, concentrating the filtrate to a relative density of 1.17, drying to obtain an extract, crushing and beating the artemisia anomala into moxa, wrapping the extract in the moxa and rolling into strips to obtain the composition for relaxing muscles and tendons and dredging collaterals.

Example 5

The embodiment provides a composition for relaxing muscles and tendons and dredging collaterals, which comprises 50g of lycopodium clavatum, 51g of garden balsam stem, 52g of herba siegesbeckiae, 27g of caulis spatholobi, 26g of caulis trachelospermi, 26g of caulis lonicerae, 27g of loofah sponge, 27g of eucommia bark, 27g of cinnamon, 27g of radix angelicae, 27g of clove, 27g of fennel, 27g of radix aucklandiae, 77g of frankincense, 17g of agilawood, 27g of rhizoma atractylodis, 27g of notopterygium root, 27g of radix angelicae pubescentis, 22g of honeycomb, 32g of dried mushroom and 1560g of south-yang moxa.

The embodiment also provides a preparation method of the composition for relaxing muscles and tendons and dredging collaterals, which comprises the following steps of grinding and sieving lycopodium clavatum, garden balsam stem, herba siegesbeckiae, caulis spatholobi, Chinese starjasmine stem, honeysuckle stem, loofah sponge, eucommia bark, cinnamon, radix angelicae, clove, fennel, elecampane, frankincense, agilawood, rhizoma atractylodis, notopterygium root, radix angelicae pubescentis, honeycomb and artemisia capillaris to obtain powder, carrying out alcohol extraction on the powder at 68 ℃ for 7 hours, filtering to remove filtrate, concentrating the filtrate to a relative density of 1.19, drying to obtain an extract, crushing and beating the artemisia anomala into moxa, wrapping the extract in the moxa and rolling into strips to obtain the composition for relaxing muscles and tendons and dredging collaterals.

Example 6

The embodiment provides a composition for relaxing muscles and tendons and dredging collaterals, which comprises 53g of lycopodium clavatum, 46g of garden balsam stem, 54g of herba siegesbeckiae, 47g of caulis spatholobi, 29g of caulis trachelospermi, 29g of caulis lonicerae, 27g of loofah sponge, 28g of eucommia bark, 21g of cinnamon, 21g of radix angelicae, 21g of clove, 21g of fennel, 29g of radix aucklandiae, 79g of frankincense, 19g of agilawood, 29g of rhizoma atractylodis, 21g of notopterygium root, 21g of radix angelicae pubescentis, 24g of honeycomb, 26g of dried mushroom and 1444g of south-yang folium artemisiae argyi.

The embodiment also provides a preparation method of the composition for relaxing muscles and tendons and dredging collaterals, which comprises the following steps of grinding and sieving lycopodium clavatum, garden balsam stem, herba siegesbeckiae, caulis spatholobi, Chinese starjasmine stem, honeysuckle stem, loofah sponge, eucommia bark, cinnamon, radix angelicae, clove, fennel, elecampane, frankincense, agilawood, rhizoma atractylodis, notopterygium root, radix angelicae pubescentis, honeycomb and artemisia capillaris to obtain powder, carrying out alcohol extraction on the powder at 61 ℃ for 7.5 hours, filtering to remove filtrate, concentrating the filtrate to a relative density of 1.20, drying to obtain an extract, crushing and beating the artemisia anomala into artemisia wool, wrapping the extract in the artemisia wool and rolling into strips to obtain the composition for relaxing muscles and tendons and dredging collaterals.

Test example 1

Selecting 30 adult and healthy SD rats with male and female halves, taking 5 rats as one group, numbering the rats in sequence as A-F groups, taking 0.5g of cartilage tissue of each rat, detecting the number of osteoblasts in the cartilage tissue by staining, and calculating the average value of the number of osteoblasts of each group of rats; taking the composition for relaxing muscles and tendons and dredging collaterals prepared in the examples 1-6, carrying out moxibustion on rats in the groups A-F in sequence, wherein the rats in the group A adopt the composition for relaxing muscles and tendons and dredging collaterals prepared in the example 1, and the like, and carrying out moxibustion continuously for seven days; 0.5g of cartilage tissue was collected from each rat and the number of osteoblasts therein was examined by staining, and then the average of the numbers of osteoblasts in each group of rats was calculated, and the results are shown in Table 1.

TABLE 1 statistical table of the number of osteoblasts in rats

As shown in the results in Table 1, the number of osteoblasts in the rat body after moxibustion is significantly greater than that in the rat body before moxibustion, so that the tendon-relaxing and collateral-dredging composition provided by the invention can strengthen tendons and bones, and relax tendons and dredge collaterals.

Test example 2

After Mr. Zhu, male, 23 years old and the leg bone of the lower leg are fractured for one week, after continuously using the composition for relaxing the muscles and stimulating the circulation of the blood vessels provided by the invention for 24 days (moxibustion is carried out for three times per week), the leg bone of the lower leg is basically healed, and the walking can be normally carried out.

Mr. wang, male and 25 years old are exposed to rain for a long time due to work reasons, and suffer from rheumatism diseases caused by dampness, after the composition for relaxing muscles and tendons provided by the invention is continuously used for two months (three times per week through moxibustion), the rheumatism pain degree is obviously improved, the phenomenon that the sleep is difficult to fall due to the rheumatism pain in the middle of the night is avoided, and the return visit after one month does not relapse.

For a 34-year-old grandson woman, the joints of the shanks deform due to long-term rheumatism, severe wind-cold symptoms are accompanied, and the pain of the joints is hard to endure after the knee-joint is wet, so that after the composition for relaxing muscles and tendons provided by the invention is continuously used for three months (three times of moxibustion every week), the wind-cold pain degree is obviously improved, and the disease recurs after 40 days.

In summary, the embodiment of the invention provides a composition for relaxing muscles and tendons and dredging collaterals, a preparation method and an application thereof:

The embodiments described above are some, but not all embodiments of the invention. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Claims

1. The composition for relaxing muscles and tendons and dredging collaterals is characterized by comprising the following raw materials, by weight, 45-55 parts of lycopodium clavatum, 45-55 parts of garden balsam stem, 45-55 parts of herba siegesbeckiae, 20-30 parts of caulis spatholobi, 20-30 parts of Chinese starjasmine stem, 20-30 parts of honeysuckle stem, 20-30 parts of loofah sponge, 20-30 parts of eucommia bark, 20-30 parts of cinnamon, 20-30 parts of radix angelicae, 20-30 parts of clove, 20-30 parts of fennel, 20-30 parts of elecampane, 70-80 parts of frankincense, 10-20 parts of agilawood, 20-30 parts of rhizoma atractylodis, 20-30 parts of notopterygium root, 20-30 parts of radix angelicae pubescentis, 15-25 parts of honeycomb and 25-35 parts of oriental wormwood.

2. The composition for relaxing muscles and tendons and activating collaterals as claimed in claim 1, further comprising 1400-1600 parts of artemisia argyi.

3. The composition for relaxing muscles and tendons and activating collaterals as claimed in claim 2, wherein the folium artemisiae argyi is south yang folium artemisiae argyi, and the tarragon is dried tarragon.

4. The composition for relaxing muscles and tendons and activating collaterals according to claim 2, which comprises the following raw materials, by weight, 50 parts of lycopodium clavatum, 50 parts of garden balsam stem, 50 parts of herba siegesbeckiae, 25 parts of caulis spatholobi, 25 parts of Chinese starjasmine stem, 25 parts of honeysuckle stem, 25 parts of loofah sponge, 25 parts of eucommia bark, 25 parts of cinnamon, 25 parts of angelica dahurica, 25 parts of clove, 25 parts of fennel, 25 parts of costus root, 75 parts of frankincense, 15 parts of agilawood, 25 parts of rhizoma atractylodis, 25 parts of notopterygium root, 25 parts of radix angelicae pubescentis, 20 parts of honeycomb, 30 parts of oriental wormwood and 1500 parts of folium artemisiae argyi.

5. Use of a composition for relaxing muscles and tendons as claimed in any one of claims 1 to 4 in the preparation of a medicament for treating rheumatism, soreness of the waist and knees.

6. A method for preparing the composition for relaxing muscles and tendons and dredging collaterals as claimed in any one of claims 1-4, comprising the steps of grinding and sieving lycopodium clavatum, garden balsam stem, herba siegesbeckiae, caulis spatholobi, Chinese starjasmine stem, honeysuckle stem, loofah sponge, eucommia bark, cinnamon, radix angelicae dahuricae, clove, fennel, elecampane, frankincense, agilawood, rhizoma atractylodis, notopterygium root, radix angelicae pubescentis, honeycomb and oriental wormwood to obtain powder, and sequentially extracting, filtering, concentrating and drying the powder to obtain the composition for relaxing muscles and tendons and dredging collaterals.

7. The preparation method of the composition for relaxing muscles and tendons and activating collaterals as claimed in claim 6, wherein the drying further comprises a final treatment, the final treatment comprises the following steps of drying to obtain an extract, wrapping the extract with folium artemisiae argyi and rolling the wrapped extract into strips to obtain the composition for relaxing muscles and tendons and activating collaterals.

8. The method for preparing a composition for relaxing muscles and tendons and activating the collaterals as claimed in claim 7, wherein the drying and the final treatment further comprise a pretreatment, and the pretreatment comprises the steps of crushing the folium artemisiae argyi and preparing the folium artemisiae argyi into moxa.

9. The preparation method of the composition for relaxing muscles and tendons according to claim 6, wherein the extraction is alcohol extraction, the temperature of the alcohol extraction is 50-80 ℃, and the time of the alcohol extraction is 5-8 h.

10. The method for preparing the composition for relaxing muscles and tendons according to claim 6, wherein the relative density of the concentrate is 1.15-1.22.