CN113727728A - 使用重组单纯疱疹病毒2(hsv-2)疫苗载体的免疫的被动转移 - Google Patents

使用重组单纯疱疹病毒2(hsv-2)疫苗载体的免疫的被动转移 Download PDF

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Publication number
CN113727728A
CN113727728A CN202080018414.0A CN202080018414A CN113727728A CN 113727728 A CN113727728 A CN 113727728A CN 202080018414 A CN202080018414 A CN 202080018414A CN 113727728 A CN113727728 A CN 113727728A
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hsv
glycoprotein
mice
subject
infection
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Pending
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CN202080018414.0A
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Chinese (zh)
Inventor
贝齐·赫罗尔德
小威廉·雅各布斯
巴勃罗·A·冈萨雷斯·米诺
克里斯托弗·皮特罗
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Albert Einstein College of Medicine
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Albert Einstein College of Medicine
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Priority claimed from US16/238,933 external-priority patent/US10918712B2/en
Application filed by Albert Einstein College of Medicine filed Critical Albert Einstein College of Medicine
Publication of CN113727728A publication Critical patent/CN113727728A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/80Vaccine for a specifically defined cancer
    • A61K2039/844Liver
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/80Vaccine for a specifically defined cancer
    • A61K2039/884Vaccine for a specifically defined cancer prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/80Vaccine for a specifically defined cancer
    • A61K2039/892Reproductive system [uterus, ovaries, cervix, testes]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16634Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
CN202080018414.0A 2019-01-03 2020-01-03 使用重组单纯疱疹病毒2(hsv-2)疫苗载体的免疫的被动转移 Pending CN113727728A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16/238,933 2019-01-03
US16/238,933 US10918712B2 (en) 2014-03-03 2019-01-03 Passive transfer of immunity using recombinant herpes simplex virus 2 (HSV-2) vaccine vectors
PCT/US2020/012170 WO2020142677A1 (en) 2019-01-03 2020-01-03 Passive transfer of immunity using recombinant herpes simplex virus 2 (hsv-2) vaccine vectors

Publications (1)

Publication Number Publication Date
CN113727728A true CN113727728A (zh) 2021-11-30

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CN202080018414.0A Pending CN113727728A (zh) 2019-01-03 2020-01-03 使用重组单纯疱疹病毒2(hsv-2)疫苗载体的免疫的被动转移

Country Status (8)

Country Link
EP (1) EP3906052A1 (ja)
JP (2) JP2022517322A (ja)
KR (2) KR102686042B1 (ja)
CN (1) CN113727728A (ja)
AU (1) AU2020204688A1 (ja)
CA (1) CA3124523A1 (ja)
IL (1) IL284448B2 (ja)
WO (1) WO2020142677A1 (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023245159A1 (en) * 2022-06-16 2023-12-21 Albert Einstein College Of Medicine Recombinant herpes simplex virus 2 (hsv-2) vectors and engineered transgenic vero cell lines

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106456805A (zh) * 2014-03-03 2017-02-22 阿尔伯特爱因斯坦医学院公司 重组单纯疱疹病毒2(hsv‑2)疫苗载体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009144755A1 (en) * 2008-05-29 2009-12-03 Alma Mater Studiorum - Universita' Di Bologna Herpes simplex virus (hsv) with modified tropism, uses and process of preparation thereof
WO2010087813A1 (en) * 2009-01-05 2010-08-05 Dcb-Usa Llc Anti-herpes simplex virus antibodies
US10918712B2 (en) * 2014-03-03 2021-02-16 Albert Einstein College Of Medicine Passive transfer of immunity using recombinant herpes simplex virus 2 (HSV-2) vaccine vectors
DE102014117280A1 (de) * 2014-11-25 2016-05-25 Pilz Gmbh & Co. Kg Sicherheitsschaltgerät zum Ein- und sicheren Ausschalten eines elektrischen Verbrauchers

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106456805A (zh) * 2014-03-03 2017-02-22 阿尔伯特爱因斯坦医学院公司 重组单纯疱疹病毒2(hsv‑2)疫苗载体

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
"孕育幸福事"编委会: "《孕妇圣典》", vol. 1, 31 January 2018, 福建科学技术出版社, pages: 274 *
PETRO ET AL.: "Herpes simplex type 2 virus deleted in glycoprotein D protects against vaginal, skin and neural disease", 《ELIFE》, vol. 4, pages 1 - 18, XP055682541, DOI: 10.7554/eLife.06054 *
ROBERT B. BELSHE ET AL.: "Efficacy Results of a Trial of a Herpes Simplex Vaccine", 《N ENGL J MED》, vol. 366, no. 1, pages 34 - 43 *
宋家兴等: "《医学微生物学》", vol. 2, 30 November 1993, 上海科学技术出版社 , pages: 326 *

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Publication number Publication date
IL284448A (en) 2021-08-31
KR20210112343A (ko) 2021-09-14
CA3124523A1 (en) 2020-07-09
KR20240116556A (ko) 2024-07-29
KR102686042B1 (ko) 2024-07-17
IL284448B2 (en) 2023-12-01
AU2020204688A1 (en) 2021-07-15
JP2024016032A (ja) 2024-02-06
IL284448B1 (en) 2023-08-01
WO2020142677A1 (en) 2020-07-09
JP2022517322A (ja) 2022-03-08
EP3906052A1 (en) 2021-11-10

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