KR102686042B1 - 재조합 단순 헤르페스 바이러스 2 (hsv-2) 백신 벡터를 사용한 면역의 수동 전달 - Google Patents

재조합 단순 헤르페스 바이러스 2 (hsv-2) 백신 벡터를 사용한 면역의 수동 전달 Download PDF

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KR102686042B1
KR102686042B1 KR1020217024471A KR20217024471A KR102686042B1 KR 102686042 B1 KR102686042 B1 KR 102686042B1 KR 1020217024471 A KR1020217024471 A KR 1020217024471A KR 20217024471 A KR20217024471 A KR 20217024471A KR 102686042 B1 KR102686042 B1 KR 102686042B1
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hsv
glycoprotein
infection
mice
composition
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KR1020217024471A
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Korean (ko)
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KR20210112343A (ko
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벳시 헤롤드
쥬니어 윌리엄 제이콥스
파블로 에이. 곤잘레스-무노즈
크리스토퍼 페트로
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앨버트 아인슈타인 컬리지 오브 메디신
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Priority claimed from US16/238,933 external-priority patent/US10918712B2/en
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Priority to KR1020247023560A priority Critical patent/KR20240116556A/ko
Publication of KR20210112343A publication Critical patent/KR20210112343A/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/80Vaccine for a specifically defined cancer
    • A61K2039/844Liver
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/80Vaccine for a specifically defined cancer
    • A61K2039/884Vaccine for a specifically defined cancer prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/80Vaccine for a specifically defined cancer
    • A61K2039/892Reproductive system [uterus, ovaries, cervix, testes]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16634Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
KR1020217024471A 2019-01-03 2020-01-03 재조합 단순 헤르페스 바이러스 2 (hsv-2) 백신 벡터를 사용한 면역의 수동 전달 KR102686042B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020247023560A KR20240116556A (ko) 2019-01-03 2020-01-03 재조합 단순 헤르페스 바이러스 2 (hsv-2) 백신 벡터를 사용한 면역의 수동 전달

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16/238,933 2019-01-03
US16/238,933 US10918712B2 (en) 2014-03-03 2019-01-03 Passive transfer of immunity using recombinant herpes simplex virus 2 (HSV-2) vaccine vectors
PCT/US2020/012170 WO2020142677A1 (en) 2019-01-03 2020-01-03 Passive transfer of immunity using recombinant herpes simplex virus 2 (hsv-2) vaccine vectors

Related Child Applications (1)

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KR1020247023560A Division KR20240116556A (ko) 2019-01-03 2020-01-03 재조합 단순 헤르페스 바이러스 2 (hsv-2) 백신 벡터를 사용한 면역의 수동 전달

Publications (2)

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KR20210112343A KR20210112343A (ko) 2021-09-14
KR102686042B1 true KR102686042B1 (ko) 2024-07-17

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KR1020247023560A KR20240116556A (ko) 2019-01-03 2020-01-03 재조합 단순 헤르페스 바이러스 2 (hsv-2) 백신 벡터를 사용한 면역의 수동 전달
KR1020217024471A KR102686042B1 (ko) 2019-01-03 2020-01-03 재조합 단순 헤르페스 바이러스 2 (hsv-2) 백신 벡터를 사용한 면역의 수동 전달

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KR1020247023560A KR20240116556A (ko) 2019-01-03 2020-01-03 재조합 단순 헤르페스 바이러스 2 (hsv-2) 백신 벡터를 사용한 면역의 수동 전달

Country Status (8)

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EP (1) EP3906052A1 (ja)
JP (2) JP2022517322A (ja)
KR (2) KR20240116556A (ja)
CN (1) CN113727728A (ja)
AU (1) AU2020204688A1 (ja)
CA (1) CA3124523A1 (ja)
IL (1) IL284448B2 (ja)
WO (1) WO2020142677A1 (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023245159A1 (en) * 2022-06-16 2023-12-21 Albert Einstein College Of Medicine Recombinant herpes simplex virus 2 (hsv-2) vectors and engineered transgenic vero cell lines

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009144755A1 (en) 2008-05-29 2009-12-03 Alma Mater Studiorum - Universita' Di Bologna Herpes simplex virus (hsv) with modified tropism, uses and process of preparation thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010087813A1 (en) * 2009-01-05 2010-08-05 Dcb-Usa Llc Anti-herpes simplex virus antibodies
CA2942166A1 (en) * 2014-03-03 2015-09-11 Albert Einstein College Of Medicine, Inc. Recombinant herpes simplex virus 2 (hsv-2) vaccine vectors
US10918712B2 (en) * 2014-03-03 2021-02-16 Albert Einstein College Of Medicine Passive transfer of immunity using recombinant herpes simplex virus 2 (HSV-2) vaccine vectors
DE102014117280A1 (de) * 2014-11-25 2016-05-25 Pilz Gmbh & Co. Kg Sicherheitsschaltgerät zum Ein- und sicheren Ausschalten eines elektrischen Verbrauchers

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009144755A1 (en) 2008-05-29 2009-12-03 Alma Mater Studiorum - Universita' Di Bologna Herpes simplex virus (hsv) with modified tropism, uses and process of preparation thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Elife 4:e06054. doi: 10.7554/eLife.06054 (2015.03.10. 공개)*
mBio. 8(4):e00678-17. doi: 10.1128/mBio.00678-17 (2017.07.05. 공개)*

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Publication number Publication date
KR20240116556A (ko) 2024-07-29
WO2020142677A1 (en) 2020-07-09
AU2020204688A1 (en) 2021-07-15
EP3906052A1 (en) 2021-11-10
KR20210112343A (ko) 2021-09-14
CN113727728A (zh) 2021-11-30
CA3124523A1 (en) 2020-07-09
JP2022517322A (ja) 2022-03-08
IL284448B2 (en) 2023-12-01
JP2024016032A (ja) 2024-02-06
IL284448A (en) 2021-08-31
IL284448B1 (en) 2023-08-01

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