CN1137270C - Preparation method for producing small molecular weight titanium by using soybean separated protein and its equipment - Google Patents
Preparation method for producing small molecular weight titanium by using soybean separated protein and its equipment Download PDFInfo
- Publication number
- CN1137270C CN1137270C CNB001033921A CN00103392A CN1137270C CN 1137270 C CN1137270 C CN 1137270C CN B001033921 A CNB001033921 A CN B001033921A CN 00103392 A CN00103392 A CN 00103392A CN 1137270 C CN1137270 C CN 1137270C
- Authority
- CN
- China
- Prior art keywords
- molecular weight
- protein isolate
- small molecular
- soybean protein
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 26
- 244000068988 Glycine max Species 0.000 title claims abstract description 6
- 235000010469 Glycine max Nutrition 0.000 title claims abstract description 6
- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 6
- 102000004169 proteins and genes Human genes 0.000 title claims abstract description 6
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 title claims description 27
- 229910052719 titanium Inorganic materials 0.000 title claims description 27
- 239000010936 titanium Substances 0.000 title claims description 27
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 37
- 239000002994 raw material Substances 0.000 claims abstract description 25
- 230000001954 sterilising effect Effects 0.000 claims abstract description 16
- 238000002156 mixing Methods 0.000 claims abstract description 15
- 102000004190 Enzymes Human genes 0.000 claims abstract description 14
- 108090000790 Enzymes Proteins 0.000 claims abstract description 14
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 13
- 239000000843 powder Substances 0.000 claims abstract description 10
- 238000000034 method Methods 0.000 claims abstract description 9
- 238000001694 spray drying Methods 0.000 claims abstract description 8
- 238000006243 chemical reaction Methods 0.000 claims abstract description 5
- 238000001035 drying Methods 0.000 claims abstract description 5
- 238000001914 filtration Methods 0.000 claims abstract description 3
- 108010073771 Soybean Proteins Proteins 0.000 claims description 36
- 235000019710 soybean protein Nutrition 0.000 claims description 36
- 238000004519 manufacturing process Methods 0.000 claims description 19
- 239000000049 pigment Substances 0.000 claims description 10
- 239000012141 concentrate Substances 0.000 claims description 9
- 230000000694 effects Effects 0.000 claims description 7
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 5
- 230000002401 inhibitory effect Effects 0.000 claims description 4
- 238000000265 homogenisation Methods 0.000 claims description 3
- 235000018102 proteins Nutrition 0.000 claims description 3
- 239000007864 aqueous solution Substances 0.000 claims description 2
- 239000002274 desiccant Substances 0.000 claims description 2
- 238000009413 insulation Methods 0.000 claims description 2
- 239000000243 solution Substances 0.000 claims description 2
- 238000010792 warming Methods 0.000 claims description 2
- 238000001976 enzyme digestion Methods 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract description 6
- 102000004196 processed proteins & peptides Human genes 0.000 abstract description 3
- 238000001816 cooling Methods 0.000 abstract 1
- 238000010979 pH adjustment Methods 0.000 abstract 1
- 230000000630 rising effect Effects 0.000 abstract 1
- 239000000047 product Substances 0.000 description 5
- 150000001413 amino acids Chemical class 0.000 description 2
- 230000000975 bioactive effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000002255 enzymatic effect Effects 0.000 description 2
- 108010083391 glycinin Proteins 0.000 description 2
- 230000007062 hydrolysis Effects 0.000 description 2
- 238000006460 hydrolysis reaction Methods 0.000 description 2
- 101100298222 Caenorhabditis elegans pot-1 gene Proteins 0.000 description 1
- 108010088395 Glycine max alpha-conglycinin Proteins 0.000 description 1
- 108700037728 Glycine max beta-conglycinin Proteins 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000017854 proteolysis Effects 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/18—Apparatus specially designed for the use of free, immobilized or carrier-bound enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/02—Stirrer or mobile mixing elements
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/10—Separation or concentration of fermentation products
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/14—Drying
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Sustainable Development (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Plant Substances (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
The present invention relates to a preparation method for preparing peptides with small molecular weight by using soybean isolated protein as raw materials and a device thereof. The method comprises: carrying out an enzymolysis reaction for the soybean isolated protein and water by mixing, sterilization, cooling, enzyme adding and pH adjustment; adjusting a pH valve, rising temperature, insulating temperature for sterilization after enzymolysis; filtering, concentrating and drying. The used device comprises a water and powder mixer, a homogenizer, a reaction tank, a filter, a concentrating tank and a spray drying tower. The method of the present invention has the characteristics of high output rate for peptides with small molecular weight, high utilization rate for raw materials, simple preparation process and low cost. The used device is scientific and reasonable, and can perfectly meet the requirement of reaction.
Description
The present invention relates to the preparation of protective foods peptide, a kind of especially is preparation method and the equipment used thereof that small molecular weight titanium is produced in raw material hydrolysis under the effect of enzyme with the soybean protein isolate.
The peptide of the nearest small molecular weight that studies show that different proteolysiss, its amino acid is formed different, and bioactive functions is also different.Can utilize its biological activity exploitation medicine and nourishing function product.Existing with enzyme hydrolysis of soybean protein isolate technology, shortcoming such as the rate of output that exists small-molecular peptides is low, energy consumption is big.
The purpose of this invention is to provide that a kind of that have that rate of output height, raw material availability height, apparatus and process are simple, economic benefit is high, energy input is lower is raw material is produced the small molecular weight titanium with unique bioactive functions under the enzyme effect preparation method with the soybean protein isolate.
Another object of the present invention provides the above-mentioned preparation method's equipment used of a cover.
Of the present invention with the soybean protein isolate be the preparation method of raw material production small molecular weight titanium be included in make soybean protein isolate and water thorough mixing in the pigment mixing tank after, through sterilization, under 49-51 ℃ temperature, add enzyme, transfer PH to 7-8 simultaneously, carry out 3.5-4.5 hour enzymolysis, behind the enzymolysis, be warming up to 85-90 ℃, be incubated sterilization in 15-25 minute and inhibitory enzyme activity, more after filtration, concentrate, drying can obtain the small molecular weight titanium power-product.
Wherein, described soybean protein isolate is a raw material production with the Heilongjiang Province soybean, contain 90% soybean protein, main component is white protein, sphaeroprotein, can be divided into glycinin, α-conglycinin, beta-conglycinin, γ-conglycinin again from immunology angle glycinin.
Described soybean protein isolate and water blended process can adopt the pigment mixing tank, and the mashed prod that mixes enters clarifixator again and carries out homogeneous after colloidal mill is levigate, and homogenization pressure is at 20-40MPa.
The concentration of aqueous solution of described soybean protein isolate is 2-8%.
Sterilising temp is that sterilization and inhibitory enzyme activity temperature behind 100 ℃ and the enzymolysis are 85 ℃ before the described enzymolysis, and insulation 15-25 minute.
Described enzyme is inscribe trypsinase or solidifies trypsinase that add-on is the 1-5% of total charging capacity.
The process of transferring PH before the described enzymolysis is to adopt the aqueous sodium hydroxide solution of 20-40%.
Described concentration process can adopt vacuum concentration pot, by pump with water through the vacuum jet device, make to reach negative pressure state in the jar and concentrate, concentrate the back material concentration and reach 40-55%.
Described drying process can adopt spray-drying tower, and the water ratio of gained dry powder is below 5%.
Of the present invention is that the preparation method of raw material production small molecular weight titanium can also comprise that institute's water is magnetized water with the soybean protein isolate; The course of processing of described magnetized water be with institute's water through High-gradient Magnetic filter treatment 4-20 second, magneticflux-density is 0.15T-0.35T in the chamber of described High-gradient Magnetic filter, this magnetized water has stronger perviousness, can quicken the enzymolysis speed of soybean protein.
Of the present invention is that preparation method's equipment used of raw material production small molecular weight titanium comprises pigment mixing tank and the high pressure homogenizer that mixing soya beans protein isolate and water are used with the soybean protein isolate, the retort that sterilization and enzymolysis are used, filter the filter of usefulness, concentrate the vacuum concentration pot and the vacuum ejector of usefulness, and desiccant spray-drying tower.
Of the present invention is that preparation method's equipment used of raw material production small molecular weight titanium can also comprise water pot, integrated water treatment facility and the High-gradient Magnetic water carburetor that treating water is used with the soybean protein isolate.
Of the present invention is that preparation method's equipment used of raw material production small molecular weight titanium can also comprise and collects the dry powder collector that finished product is used with the soybean protein isolate.
The present invention is to be the small molecular weight titanium of biologically active function with the soybean protein isolate enzymolysis, and small molecular weight titanium (molecular weight is below 3000) output capacity height is 40-60%; The raw material availability height, enzymolysis efficiency reaches 45-60%, and main products is a small molecular weight titanium, and amino acid only accounts for about 2-10%; Technology is simple, and management is simplified, thereby has reduced the cost of product, has improved economic benefit.Equipment used is scientific and reasonable, can satisfy the reaction requirement fully.
Further describe the present invention below in conjunction with drawings and Examples.
Accompanying drawing 1 for of the present invention be preparation method's equipment used schema of raw material production small molecular weight titanium with the soybean protein isolate.
Wherein, label 1 is former water pot, and 2 is the integrated water treatment facility, 3 is the High-gradient Magnetic water carburetor, and 4 is the soybean protein isolate charging device, and 5 is the pigment mixing tank, 6 is colloidal mill, 7 is high pressure homogenizer, and 8 are the sterilization enzymatic vessel, and 9 is filter, 10 is vacuum concentration pot, 11 is vacuum ejector, and 12 is spray-drying tower, and 13 is the dry powder collector.
A kind of preparation method who with the soybean protein isolate is little son of raw material production measured peptide as shown in the figure is: tap water is sent into integrated water treatment facility 2 from former water pot 1 by water pump, arrive in the pigment mixing tank 5 through High-gradient Magnetic water carburetor 3 again, by soybean protein isolate charging device 4 soybean protein isolate is put in the pigment mixing tank 5 simultaneously.Mix through the pigment mixing tank, this moment, material concentration was controlled at 5%, the mashed prod that mixes enters colloidal mill 6 porphyrizes, enters clarifixator 7 homogeneous again, and homogenization pressure is at 25MPa, mashed prod behind the homogeneous enters sterilization enzymatic vessel 8, sterilising temp is 100 ℃, is incubated 15 minutes, is cooled to 50 ℃, add inscribe trypsinase, the enzyme add-on is 3%, and transferring PH is 8, enzymolysis 4 hours, enzymolysis post-heating to 85 ℃, kept 20 minutes, and promptly reached sterilization functions enzyme is lost activity, material filters by being pumped into filter 9 then, filtrate enters vacuum concentration pot 10, and filter residue can be as other purposes.Vacuum concentration pot concentrates the back strength of fluid and reaches about 50%, concentrates the back material by being pumped into spray-drying tower 12, and the dry powder water ratio that spray-drying tower is discharged is below 5%, is collected dry powder and is delivered to packing shop by dry powder collector 13.
This suit is changed to the batch operation device, 200 kilograms of day processing soybean protein isolates, but output contains about 160 kilograms of the dry powder of small molecular weight titanium 50%.
Claims (13)
1, a kind of is the preparation method of raw material production small molecular weight titanium with the soybean protein isolate, it is characterized in that being included in make soybean protein isolate and water thorough mixing in the pigment mixing tank after, through sterilization, under 49-51 ℃ temperature, add enzyme, transfer PH to 7-8 simultaneously, carry out 3.5-4.5 hour enzyme digestion reaction, behind the enzymolysis, be warming up to 85-90 ℃, be incubated sterilization in 15-25 minute and inhibitory enzyme activity, concentrated after filtration again, drying can obtain the small molecular weight titanium power-product.
2, as claimed in claim 1 is the preparation method of raw material production small molecular weight titanium with the soybean protein isolate, it is characterized in that described soybean protein isolate and water blended process adopt the pigment mixing tank, the mashed prod that mixes carries out homogeneous through the levigate clarifixator that enters again of colloidal mill, and homogenization pressure is at 20-40Mpa.
3, as claimed in claim 1 is the preparation method of raw material production small molecular weight titanium with the soybean protein isolate, and the concentration of aqueous solution that it is characterized in that described soybean protein isolate is 2-8%.
4, as claimed in claim 1 is the preparation method of raw material production small molecular weight titanium with the soybean protein isolate, it is characterized in that before the described enzymolysis 85 ℃ of the sterilizations behind 100 ℃ of the sterilising temps and enzymolysis and inhibitory enzyme activity temperature, and insulation 15-25 minute.
5, as claimed in claim 1 is the preparation method of raw material production small molecular weight titanium with the soybean protein isolate, it is characterized in that described enzyme is inscribe trypsinase or solidifies trypsinase, and add-on is the 1-5% of total charging capacity.
6, as claimed in claim 1 is the preparation method of raw material production small molecular weight titanium with the soybean protein isolate, and the process that it is characterized in that the preceding PH of accent of described enzymolysis is to adopt the aqueous sodium hydroxide solution of 20-40%.
7, as claimed in claim 1 is the preparation method of raw material production small molecular weight titanium with the soybean protein isolate, it is characterized in that described concentration process adopts vacuum concentration pot, by pump with water through the vacuum jet device, make to reach negative pressure state in the jar and concentrate; Concentrate the back material concentration and reach 40-55%.
8, as claimed in claim 1 is the preparation method of raw material production small molecular weight titanium with the soybean protein isolate, it is characterized in that described drying process adopts spray-drying tower, and the water ratio of gained dry powder is below 5%.
9, as claimed in claim 1 is the preparation method of raw material production small molecular weight titanium with the soybean protein isolate, it is characterized in that also comprising that institute's water is magnetized water.
10, as claimed in claim 9 is the preparation method of raw material production small molecular weight titanium with the soybean protein isolate, the course of processing that it is characterized in that described magnetized water be with institute's water through High-gradient Magnetic filter treatment 4-20 second, magneticflux-density is 0.15T-0.35T in the chamber of described High-gradient Magnetic filter.
11, one the cover be exclusively used in as claim 1-10 any one described be preparation method's equipment used of raw material production small molecular weight titanium with the soybean protein isolate, it is characterized in that the pigment mixing tank and the high pressure homogenizer that comprise that mixing soya beans protein isolate and water are used, the retort that sterilization and enzymolysis are used, filter the filter of usefulness, concentrate the vacuum concentration pot and the vacuum ejector of usefulness, and desiccant spray-drying tower.
12, equipment as claimed in claim 11 is characterized in that the water pot, integrated water treatment facility and the High-gradient Magnetic water carburetor that comprise that also treating water is used.
13, equipment as claimed in claim 11 is characterized in that the dry powder collector that comprises that also the collection finished product is used.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001033921A CN1137270C (en) | 2000-03-01 | 2000-03-01 | Preparation method for producing small molecular weight titanium by using soybean separated protein and its equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001033921A CN1137270C (en) | 2000-03-01 | 2000-03-01 | Preparation method for producing small molecular weight titanium by using soybean separated protein and its equipment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1268574A CN1268574A (en) | 2000-10-04 |
| CN1137270C true CN1137270C (en) | 2004-02-04 |
Family
ID=4576950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB001033921A Expired - Fee Related CN1137270C (en) | 2000-03-01 | 2000-03-01 | Preparation method for producing small molecular weight titanium by using soybean separated protein and its equipment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1137270C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100569795C (en) * | 2007-04-28 | 2009-12-16 | 中国农业科学院蜜蜂研究所 | A kind of oxidation resistance zymolyte that is rich in pollen active peptide |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100343392C (en) * | 2002-11-12 | 2007-10-17 | 陆晓民 | Process for producing soybean protein peptide using soybean as raw material |
| CN100385010C (en) * | 2003-02-25 | 2008-04-30 | 中国人民解放军军需大学 | Soybean oligopeptide production process |
| CN103876139B (en) * | 2014-03-18 | 2016-05-18 | 广州金酮医疗科技有限公司 | A kind of dietary composition that is used for the treatment of self-closing disease and preparation method thereof |
| CN106397561A (en) * | 2016-09-14 | 2017-02-15 | 山东天久生物技术有限公司 | Method for preparing soybean Aglycin family peptide by using acetic acid |
| CN110973346A (en) * | 2019-12-04 | 2020-04-10 | 荣海生物科技有限公司 | Method for adjusting pH value of isolated soy protein |
| CN111004829A (en) * | 2019-12-30 | 2020-04-14 | 伊春林业科学院 | Preparation method of black fungus active peptide |
-
2000
- 2000-03-01 CN CNB001033921A patent/CN1137270C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100569795C (en) * | 2007-04-28 | 2009-12-16 | 中国农业科学院蜜蜂研究所 | A kind of oxidation resistance zymolyte that is rich in pollen active peptide |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1268574A (en) | 2000-10-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1135267C (en) | Method for preparing soybean polypeptide by utilizing ereyme method | |
| CN101096696B (en) | Industrial production method of corn protein polypeptide from corn protein powder by enzymatical process | |
| CN102329846A (en) | Pollution-free production method for producing soybean and silkworm chrysalis composite oligopeptides by adopting composite enzyme hydrolysis method | |
| CN105385740A (en) | Membrane filtration method for preparing mulberry leaf protein polypeptide under assistance of microwaves | |
| CN1137270C (en) | Preparation method for producing small molecular weight titanium by using soybean separated protein and its equipment | |
| CN103642853B (en) | A kind of L MALIC ACID novel technology for extracting | |
| CN103045707A (en) | Method for preparing rice protein active polypeptide through continuous enzymolysis and secondary membrance filtering and purification | |
| CN111154824A (en) | Industrial production method for obtaining spirulina antioxidant oligopeptide through high-concentration two-step enzymolysis | |
| CN103739663B (en) | Microwave-assisted acid hydrolysis prepares the method for little peptide ammino acid fast | |
| CN101096697A (en) | Industrial production method of ovum protein polypeptide from fowl ovum by enzymatical process | |
| CN102422976A (en) | Preparation method for gingko polypeptide | |
| CN1957736B (en) | Method for producing soyabean protein (peptide) powder with NSI value equal to 100% | |
| CN111748046A (en) | Efficient extraction method of selenium polysaccharide from selenium-enriched mushroom powder | |
| CN100506276C (en) | Preparation of cotton-seed polypeptide with anti-oxidant function | |
| CN103421868A (en) | Preparation method of tuna skin collagen micro-molecular peptides | |
| CN103421871A (en) | Preparation method of tuna bone collagen peptide | |
| CN102559817A (en) | Method for recovering protein from soybean whey wastewater | |
| CN110759754B (en) | Harmless treatment and resource utilization method of glucosamine fermentation bacterium residues | |
| CN102180991B (en) | Comprehensive utilization method of pumpkin | |
| CN1135266C (en) | Process and equipment for preparing low-molecular peptide from sodium caseinate as raw material | |
| CN107653289A (en) | A kind of industrialized production kardiseed active peptide and preparation method | |
| CN104788533B (en) | A kind of method for producing oligopeptides and amino acid from high temperature grouts using subcritical water | |
| CN100560731C (en) | A kind of is the technology of raw material production nisin with the plant cake | |
| CN109452446A (en) | A kind of preparation method of sunflower seeds antioxidation polypeptide beverage | |
| CN111154823A (en) | Millet active peptide and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: CHANGCHUN XIN'AN PHARMACEUTICAL CO., LTD. Free format text: FORMER OWNER: LIU SHUJUN Effective date: 20100511 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 150010 HARBIN SANLEYUAN GROUP CO., LTD, NO.10, WEST SHIDAO STREET, DIAOLI DISTRICT, HARBIN CITY, HEILONGJIANG PROVINCE TO: 130216 HELONG ECONOMIC DEVELOPMENT ZONE, CHANGCHUN CITY |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20100511 Address after: Helong Economic Development Zone 130216 Changchun Patentee after: Changchun Xinan Pharmaceutical Co.,Ltd. Address before: 150010 Heilongjiang city of Harbin province Daoli District West ten Street No. 10 Harbin sanleyuan group company Patentee before: Liu Shujun |
|
| DD01 | Delivery of document by public notice |
Addressee: Changchun Xinan Pharmaceutical Co.,Ltd. Document name: Notification to Pay the Fees |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20040204 Termination date: 20160301 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |