CN113706984B - Synchronous analog calibration device and method for blood pressure and reflective photoelectric accumulated wave - Google Patents

Synchronous analog calibration device and method for blood pressure and reflective photoelectric accumulated wave Download PDF

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CN113706984B
CN113706984B CN202110902896.2A CN202110902896A CN113706984B CN 113706984 B CN113706984 B CN 113706984B CN 202110902896 A CN202110902896 A CN 202110902896A CN 113706984 B CN113706984 B CN 113706984B
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陈翔
南子琪
李津
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Shaanxi Huachen Petroleum Technology Co ltd
Suzhou Sanlang Medical Technology Co ltd
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Xian Jiaotong University
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Abstract

The invention provides a synchronous analog calibration device and method for blood pressure and reflection-type photoelectric volume waves, which can simply and easily provide synchronous analog calibration for noninvasive blood pressure measurement based on pulse wave conduction velocity. Comprises a simulated heart, a red or brown liquid used as simulated blood is filled in the simulated heart, and a simulated blood inlet and a simulated blood outlet are arranged on the simulated heart; the electric push rod is used for periodically extruding the simulated heart; simulating a forearm, adopting a cylindrical elastic container, and filling colorless transparent liquid into the forearm; the simulated blood vessel adopts a transparent elastic pipeline, and two ends of the transparent elastic pipeline are respectively connected with a simulated blood inlet and a simulated blood outlet; one end of the simulated blood vessel connected with the simulated blood outlet is provided with an outflow one-way valve, and one end of the simulated blood vessel connected with the simulated blood inlet is provided with an inflow one-way valve; the simulated blood vessel penetrates through the simulated forearm along the axial direction; two reflective photoelectric volume wave sensors for measuring the analog blood vessel photoelectric volume wave signals; a blood pressure sensor for directly measuring the blood pressure of a simulated blood vessel.

Description

Synchronous analog calibration device and method for blood pressure and reflection type photoelectric accumulated wave
Technical Field
The invention relates to the field of biomedical engineering, in particular to a synchronous simulation calibration device and method for blood pressure and reflective photoelectric accumulated wave.
Background
Blood Pressure (BP) is a lateral pressure that acts on the wall of a blood vessel of a unit area when blood flows in the blood vessel, and is composed of factors such as pressure generated by the heart beat and elastic tension of the blood vessel. As an important vital sign measurement parameter, the detection of blood pressure plays an irreplaceable role in the process of disease diagnosis and medical care.
The measurement of blood pressure includes direct and indirect methods: the direct method is a method of directly measuring blood pressure by puncturing a catheter percutaneously until a blood vessel is in direct contact with blood and then coupling the blood pressure to an extracorporeal pressure sensor through liquid, and although the method is accurate and reliable, the method is only limited to the intensive care field because the operation has certain risks due to the invasiveness. The cuff method, which is mainly used in the indirect method at present, couples the blood pressure to the outside of the body through the upper arm cuff or the forearm cuff for measurement, and has low accuracy although being noninvasive, and the cuff is required to be continuously pressurized for continuous measurement.
The non-invasive blood pressure measurement method based on the pulse wave conduction velocity, which is rapidly developed in recent years, has better user experience and is more and more widely applied due to the fact that the method is non-invasive and does not need additional cuff pressurization. In fact, the pulse wave conduction velocity has a certain functional relationship with the blood pressure, and the blood pressure information can be indirectly obtained by measuring the pulse wave conduction velocity. The pulse wave velocity can be measured by the mean value of the electrocardio sensor and the photoelectric volume wave sensor together, or by the mean value of the two distant photoelectric volume wave sensors, or by the instantaneous value of the two closely adjacent reflective photoelectric volume wave sensors.
The PhotoPlethysmoGraphy, also called PhotoPlethysmoGraphy (PPG), mentioned here is a non-invasive detection method for detecting changes in blood volume in living tissue by means of optoelectronics: that is, when a light beam with a certain wavelength is irradiated on the skin surface of the finger tip, the light beam is transmitted to the photoelectric receiver by transmission or reflection. In the process, the light intensity detected by the photoelectric receiver will be weakened due to the absorption and attenuation of the finger tip skin muscle tissue and blood. Wherein the absorption of light by skin, muscle and tissue is constant throughout the blood circulation, while the volume of blood in the skin is pulsated under the action of the systolic and diastolic action. When the heart contracts, the blood volume of the peripheral blood vessel is the maximum, the light absorption amount is also the maximum, and the detected light intensity is the minimum; when the heart is in diastole, on the contrary, the blood volume of the peripheral blood vessel is the minimum, the detected light intensity is the maximum, and the light intensity detected by the photoelectric receiver is in pulsatile change. The light intensity variation signal is converted into an electric signal, and the volume variation of the pulsating blood flow can be obtained after the electric signal passes through an amplifier.
It is clear that the blood pressure and photoplethysmography are naturally synchronized with the beating of the heart. However, in practical applications, the noninvasive blood pressure measurement method based on pulse wave velocity is still lack of an effective synchronous calibration device for blood pressure and reflection-type photoelectric volume waves, so that direct calibration is difficult, blood pressure calibration has to be indirectly performed by means of other calibrated blood pressure measurement methods and devices, the use is very inconvenient, and the calibration accuracy cannot meet ideal requirements due to more links.
Disclosure of Invention
Aiming at the problems in the prior art, the invention provides a synchronous analog calibration device and method for blood pressure and reflection type photoelectric volume waves, which can simply and easily provide synchronous analog simulation calibration for noninvasive blood pressure measurement based on pulse wave conduction velocity.
The invention is realized by the following technical scheme:
a synchronous analog simulation calibration device for blood pressure and reflective photoelectric integrated wave comprises,
the heart simulator comprises a simulated heart, wherein the simulated heart adopts a cubic elastic container, red or brown liquid used as simulated blood is filled in the simulated heart, and a simulated blood inlet and a simulated blood outlet are arranged on the simulated heart;
the movable end of the electric push rod is contacted with the outer wall of the simulated heart and is used for periodically extruding the simulated heart;
a simulated forearm, wherein the simulated forearm adopts a cylindrical elastic container, and the interior of the simulated forearm is filled with colorless transparent liquid;
the simulated blood vessel adopts a light-transmitting elastic pipeline, and two ends of the simulated blood vessel are respectively connected with a simulated blood inlet and a simulated blood outlet; one end of the simulated blood vessel connected with the simulated blood outlet is provided with an outflow one-way valve, and one end of the simulated blood vessel connected with the simulated blood inlet is provided with an inflow one-way valve; the simulated blood vessel penetrates through a simulated forearm along the axial direction;
the two reflective photoelectric volume wave sensors are sequentially arranged on the outer side wall of the simulation front arm along the axial direction;
the blood pressure sensor is used for measuring the blood pressure of the simulated blood vessel by a direct method, and the blood pressure sensor is provided with one end of the simulated blood vessel connected with the simulated blood outlet and is positioned at the downstream of the outflow check valve.
Preferably, the electric push rod is provided with a push rod controller for generating a push rod driving signal for adjusting the period and the stroke of the electric push rod according to the received blood pressure waveform.
Preferably, a damper is disposed within the simulated blood vessel between the simulated blood inlet and the inflow check valve.
Preferably, a cuff is wrapped at the outer side of the simulated forearm close to the simulated heart end, and a manual inflation ball is communicated and arranged on the cuff.
Preferably, the colorless, transparent liquid simulating the filling of the interior of the forearm is water.
Preferably, the maximum working frequency of the electric push rod is 5Hz, the maximum running speed is 100mm/s, and the maximum working stroke is 10 mm.
Preferably, the range of the blood pressure sensor is 50-300 mmHg.
A synchronous analog simulation calibration method for blood pressure and reflective photoelectric integrated wave comprises,
controlling the electric push rod to periodically extrude the simulated heart to enable the simulated heart to generate deformation, and pushing red or brown simulated blood in the simulated heart into the simulated blood vessel to generate pulsating blood flow;
directly measuring the simulated blood pressure in the simulated blood vessel by a blood pressure sensor;
the periodic volume change caused by pulsating blood flow in a simulated blood vessel is respectively detected by two reflective photoelectric volume wave sensors on the outer sides of the simulated forearms, and the local instantaneous pulse wave conduction velocity is determined and the blood pressure information related to the pulse wave conduction velocity is obtained according to the time delay between the characteristic points of the reflective photoelectric volume wave waveform detected by the two sensors;
and comparing the synchronously acquired simulated blood pressure with the blood pressure information based on the pulse wave conduction velocity to realize synchronous simulation calibration of the blood pressure and the reflective photoelectric volume wave.
Preferably, the method further comprises the step of,
the gas pressure information in the cuff is detected by using a commercial cuff type electronic sphygmomanometer, the non-invasive blood pressure is measured by an indirect method according to a non-invasive cuff type blood pressure measuring method,
and comparing the noninvasive blood pressure acquired synchronously with the blood pressure information based on the pulse wave conduction velocity to realize synchronous analog simulation calibration of the blood pressure and the reflective photoelectric volume wave.
Compared with the prior art, the invention has the following beneficial technical effects:
the invention imitates the composition of the blood circulation system of the living body on the system structure, uses the program control electric push rod to extrude and imitate the heart in order, thus produce the blood pressure waveform similar to human body in the imitation blood vessel; simulating a human heart valve by using an outflow one-way valve and an inflow one-way valve which are connected on the simulated blood vessel, and controlling the simulated blood to flow in a single direction in the simulated blood vessel; meanwhile, the light-permeable simulated blood vessel and the red or brown simulated blood are used so that the reflective photoelectric volume wave monitoring device can detect the reflective photoelectric volume wave signal which changes along with the change of the blood pressure. Therefore, the simple and feasible blood pressure and reflection type photoelectric volume wave synchronous analog simulation device is realized, the blood pressure calibration based on the pulse wave conduction velocity is realized, and the device has the advantages of simple and compact structure and low cost. The amplitude of the generated simulated blood pressure is accurate and controllable, and the waveform characteristics are clear; the photoelectric volume wave has high amplitude and low noise, and is easy to observe and convenient to measure. The reflective photoelectric volume wave blood pressure measuring method based on the pulse wave conduction time can be evaluated and tested for research and calibration.
Furthermore, the damper is used for simulating the damping consumption effect of the capillary network of the human body on blood flow, so that the reflection of blood pressure signals in blood vessels is avoided.
Further, the obtained blood pressure information can be further evaluated by different noninvasive cuff-type blood pressure measurement methods using a commercial cuff-type electronic sphygmomanometer, utilizing the change in the pressure in the cuff.
Drawings
Fig. 1 is a schematic structural diagram of the calibration device in the embodiment of the present invention.
Fig. 2 shows the synchronous blood pressure signal and the reflective photoelectric volume wave signal generated by the calibration device recorded by the BIOPAC MP150 multi-channel physiological recorder in the embodiment of the invention.
In the figure: the device comprises a push rod controller 1, an electric push rod 2, a simulated heart 3, simulated blood 4, a blood pressure sensor 5, an outflow one-way valve 6, an inflow one-way valve 7, a damper 8, a simulated blood vessel 9, a cuff 10, a first reflection type photoelectric volume wave sensor 11, a second reflection type photoelectric volume wave sensor 12, a simulated forearm 13 and a manual inflation ball 14.
Detailed Description
The present invention will now be described in further detail with reference to specific examples, which are intended to be illustrative, but not limiting, of the invention.
The invention provides a synchronous analog calibration device and method for blood pressure and reflective photoelectric volume wave, aiming at the problems that the existing method is lack of an effective blood pressure and reflective photoelectric volume wave synchronous analog calibration device, so that a reflective photoelectric volume wave blood pressure measuring method based on pulse wave conduction time is difficult to directly calibrate, other calibrated blood pressure measuring methods and devices have to be used for indirectly calibrating the blood pressure, and the use is very inconvenient. The present invention includes the steps of providing,
the simulated heart 3 is a cuboidal elastic container, red or brown liquid used as simulated blood 4 is filled in the simulated heart, and a simulated blood inlet and a simulated blood outlet are arranged on the simulated heart; the cuboidal elastic container is made of polyethylene terephthalate (PET);
the movable end of the electric push rod 2 is contacted with the outer wall of the simulated heart 3 and is used for periodically extruding the simulated heart 3;
a simulation forearm 13 which is a cylindrical elastic container and is filled with colorless and transparent liquid; the cylindrical elastic container is made of polyethylene terephthalate (PET);
the simulated blood vessel 9 adopts an elastic pipeline, and two ends of the simulated blood vessel 9 are respectively connected with a simulated blood inlet and a simulated blood outlet; one end of the simulated blood vessel connected with the simulated blood outlet is provided with an outflow one-way valve 6, and one end connected with the simulated blood inlet is provided with an inflow one-way valve 7; the simulated blood vessel penetrates through the simulated forearm 13 along the axial direction; the elastic conduit is made of medical grade polyvinyl chloride (PVC);
two reflective photoelectric volume wave sensors 11 and 12 for measuring the simulated blood vessel photoelectric volume wave signals, wherein the two reflective photoelectric volume wave sensors are sequentially arranged on the side wall of a simulated forearm 13 along the axial direction;
the blood pressure sensor 5 is used for measuring the blood pressure of the simulated blood vessel by a direct method, and the blood pressure sensor 5 is arranged at one end of the simulated blood vessel connected with the simulated blood outlet and is positioned at the downstream of the outflow check valve 6.
When the device is used, the electric push rod 2 is controlled to periodically extrude the simulated heart 3, so that the elastic container 3 deforms, and the simulated blood in the simulated heart 3 is pushed into the simulated blood vessel to generate pulsating blood flow;
the simulated blood pressure in the simulated blood vessel is directly measured by the blood pressure sensor 5;
the periodic volume change caused by pulsating blood flow in a simulated blood vessel in a simulated forearm is respectively detected by the two reflective photoelectric volume wave sensors, and the reflective photoelectric volume wave containing the blood pressure information is obtained according to the time delay of the waveform characteristic point detected between the two reflective photoelectric volume wave sensors;
the blood pressure information extracted from the synchronously collected blood pressure and the reflection-type photoelectric volume waves is compared, and the blood pressure simulation calibration based on the pulse wave conduction velocity can be realized.
Wherein, the electric push rod 2 is provided with a push rod controller 1 which is used for generating a push rod driving signal for adjusting the period and the stroke of the electric push rod 2 according to the received blood pressure waveform. The maximum working frequency of the electric push rod 2 is 5Hz, the maximum running speed is 100mm/s, and the maximum working stroke is 10 mm.
A damper 8 is arranged in an elastic pipeline 9 between the simulated blood inlet and the inflow check valve 7 and used for simulating the damping effect of a human capillary network and avoiding the back-and-forth reflection of the simulated blood in the simulated blood vessel.
Specifically, as shown in fig. 1, the push rod controller 1 controls the electric push rod 2 to press the simulated heart 3, the simulated blood 4 in the simulated heart is driven to flow in a pulsating manner along the simulated blood vessel 9 in a counterclockwise direction under the constraint of the outflow check valve 6 and the inflow check valve 7, the pressure applied to the simulated blood 4 in the simulated blood vessel 9 is directly measured by the direct blood pressure sensor 5, the periodic volume change of the simulated blood vessel 9 in the simulated forearm 13 under the action of the pulsating blood flow causes the first and second two photoelectric capacitance volume wave sensors 11, 12 mounted on the simulated forearm 13 to sense and record the reflective photoelectric capacitance wave related to the blood pressure, the direct calibration of the reflection type photoelectric volume wave blood pressure measuring method based on the pulse wave conduction velocity can be realized by researching the relationship between the blood pressure measured by the direct method and the blood pressure information detected in the reflection type photoelectric volume wave.
As shown in fig. 1, the following components are specifically included:
the push rod controller 1 is used for generating a push rod driving signal with adjustable period and stroke related to blood pressure waveform and driving the electric push rod 2 to do reciprocating motion;
the electric push rod 2 is driven by the push rod controller 1 and the push rod controller to periodically extrude the elastic simulated heart 3 and push the simulated blood 4 to generate pulsating blood flow in the simulated blood vessel 9;
the simulated heart 3 is a cube-shaped elastic polyethylene terephthalate (PET) container and is used for generating deformation under the pushing of the electric push rod 2 and pushing the simulated blood 4 in the simulated heart into the simulated blood vessel 9 to generate pulsating blood flow;
the simulated blood 4 adopts red or tawny liquid, fills the simulated heart 3 and the simulated blood vessel 9, and is pushed into the simulated blood vessel 9 by the simulated heart 3 under the pushing of the electric push rod 2 to generate pulsating blood flow;
the blood pressure sensor 5 of the direct method is positioned between the downstream of the outflow check valve 6 and the upstream inlet of the simulated blood vessel 9, the inflow and outflow ports of the sensor are respectively connected with the downstream of the outflow check valve 6 and the upstream inlet of the simulated blood vessel 9, the sensing part is in direct contact with the simulated blood 4 and is used for directly measuring the blood pressure signal in the simulated blood vessel 9, and preferably, the blood pressure sensor 5 is a blood pressure transducer of BIOPAC company TSD 104A;
the outflow one-way valve 6 is positioned at a downstream outlet of the simulated heart 3, is communicated in a one-way mode and is used for dredging the simulated blood 4 to flow to an inlet of the simulated blood vessel 9 so as to avoid the simulated blood from being retained in the simulated heart 3;
the inflow check valve 7 is positioned at an upstream inlet of the simulated heart 3, is communicated in a single direction and is used for dredging the simulated blood 4 to flow to the inlet of the simulated heart 3 so as to avoid the simulated blood from being detained in the simulated blood vessel 9;
the damper 8 is used for simulating the damping action of a capillary network of a human body and avoiding the back-and-forth reflection of the simulated blood in the simulated blood vessel;
the simulated blood vessel 9 adopts a medical grade polyvinyl chloride (PVC) elastic pipeline to provide a flow channel for simulated blood 4; the simulated blood vessel 9 is connected with two ends of the simulated heart 3, passes through the outflow check valve 6, the direct method blood pressure sensor 5, penetrates through the simulated forearm 13, passes through the inflow check valve 7 and the damper 8, and then returns to the simulated heart 3;
the cuff 10 is wrapped on the outer side of the simulated forearm 13 near the simulated heart end and is connected with a manual inflation ball 14, the manual inflation ball 14 maintains the gas pressure in the cuff 10, a commercial cuff type electronic sphygmomanometer is used for detecting the gas pressure information in the cuff, namely, the relationship between the measured blood pressure and the detected blood pressure information in the reflective photoelectric volume wave can be researched by an indirect method according to different noninvasive cuff type blood pressure measuring methods, and the calibration of the reflective photoelectric volume wave blood pressure measuring method based on the pulse wave conduction velocity can also be realized.
The first reflective photoelectric volume wave sensor 11 is used for detecting the periodic pulse volume change caused by blood flow in the simulated blood vessel in the simulated forearm;
the second reflective photoelectric volume wave sensor 12 is used for detecting the periodic pulse volume change caused by blood flow in the simulated blood vessel in the simulated forearm; due to the difference of the space positions, a time delay exists between the characteristic points of the waveform of the photoplethysmogram detected by the first reflection-type photoplethysmogram sensor 11 and the second reflection-type photoplethysmogram sensor 12 respectively, the reciprocal of the time delay is the local instantaneous pulse wave conduction velocity, and the instantaneous blood pressure in the simulated blood vessel and the square value of the pulse wave conduction velocity between the two measurement points are in a functional relation;
the simulated forearm 13 is a cylindrical polyethylene terephthalate (PET) elastic container to simulate the forearm of a human body; the diameter of the liquid is approximately equal to that of the forearm of a human body, and the interior of the liquid is filled with colorless transparent liquid, preferably water. Through which a simulated blood vessel 9 extends.
The manual inflatable ball 14 is connected with the cuff 10, and can provide different levels of air pressure for the cuff 10, and provide different air pressure change modes according to different blood pressure measurement methods.
Wherein, the push rod controller 1 can provide working time less than 0.1 second and rest time less than 0.1 second, that is, can provide control signal of 5Hz working frequency at most; the electric push rod 2 can provide a working stroke of 10mm, namely the maximum running speed of the electric push rod 2 is 100 mm/s; the blood pressure sensor 5 can provide a range of-50 mmHg to 300mmHg by a direct method.
The invention imitates the composition of the blood circulation system of the organism from the system structure, use the programmable electric push rod 2 to squeeze the analog heart 3 orderly under the control of the push rod controller 1, thus produce the blood pressure waveform similar to human body in the analog blood vessel 9; simulating a human heart valve by using an outflow one-way valve 6 and an inflow one-way valve 7 which are connected on a simulated blood vessel 9, and controlling the simulated blood 4 to flow in the simulated blood vessel 9 in a single direction; the damper 8 is used for simulating the damping consumption effect of a capillary network of a human body on blood flow, so that the reflection of blood pressure is avoided; meanwhile, the light-permeable simulated blood vessel and the red or brown simulated blood 4 are used so that the reflective photoelectric volume wave monitoring device can detect the reflective photoelectric volume wave which changes along with the change of the blood pressure. Thereby realizing a simple and easy blood pressure and reflection type photoelectric volume wave synchronous simulation device. The device has simple and compact structure and low cost. As shown in figure 2, the amplitude of the generated simulated blood pressure is accurate and controllable, and the waveform characteristics are clear; the measured photoelectric volume wave has high amplitude and low noise, is easy to observe and is convenient to measure. PPG (photoplethysmography) as a characteristic point of a photoplethysmogram under the condition of maintaining the same blood pressure levelpeakWith blood pressure waveform characteristic point BPpeakWith a stable delay time deltat in between.

Claims (9)

1. A synchronous analog simulation calibration device for blood pressure and reflection-type photoelectric integrated wave is characterized by comprising,
the simulated heart (3) adopts a cubic elastic container, red or brown liquid used as simulated blood (4) is filled in the simulated heart, and a simulated blood inlet and a simulated blood outlet are arranged on the simulated heart;
the movable end of the electric push rod (2) is contacted with the outer wall of the simulated heart (3) and is used for periodically squeezing the simulated heart (3);
a simulation forearm (13), which adopts a cylindrical elastic container and is filled with colorless transparent liquid;
the simulated blood vessel (9) adopts a light-transmitting elastic pipeline, and two ends of the simulated blood vessel are respectively connected with a simulated blood inlet and a simulated blood outlet; one end of the simulated blood vessel connected with the simulated blood outlet is provided with an outflow one-way valve (6), and one end connected with the simulated blood inlet is provided with an inflow one-way valve (7); the simulated blood vessel penetrates through a simulated forearm (13) along the axial direction;
two reflective photoelectric volume wave sensors (11, 12) for measuring the simulated blood vessel photoelectric volume wave signals, wherein the two reflective photoelectric volume wave sensors are sequentially arranged on the outer side wall of a simulated forearm (13) along the axial direction;
the blood pressure sensor (5) is used for measuring the blood pressure of the simulated blood vessel by a direct method, and the blood pressure sensor (5) is arranged at one end of the simulated blood vessel connected with the simulated blood outlet and is positioned at the downstream of the outflow one-way valve (6).
2. A synchronous analog simulation calibrating device for blood pressure and reflective photoelectric volume wave according to claim 1, wherein the electric push rod (2) is provided with a push rod controller (1) for generating a push rod driving signal for adjusting the period and the stroke of the electric push rod (2) according to the received blood pressure waveform.
3. A synchronous analog calibrating device for blood pressure and reflection-type photoelectric volume waves according to claim 1, characterized in that a damper (8) is arranged in the analog blood vessel (9) between the analog blood inlet and the inflow check valve (7).
4. The synchronous analog calibration device for blood pressure and reflection type photoelectric volume waves according to claim 1, wherein a cuff (10) is wrapped at the outer side of the analog forearm (13) near the analog heart end, and a manual inflation ball (14) is communicated with the cuff (10).
5. A blood pressure and reflection type photoelectric volume wave synchronous analog simulation calibration device according to claim 1, characterized in that the colorless and transparent liquid filled in the inside of the simulation forearm (13) adopts water.
6. A synchronous analog simulation calibration device for blood pressure and reflection type photoelectric volume waves according to claim 1, characterized in that the maximum working frequency of the electric push rod (2) is 5Hz, the maximum operation speed is 100mm/s, and the maximum working stroke is 10 mm.
7. A blood pressure and reflective photoelectric volume wave synchronous analog simulation calibration device according to claim 1, wherein the range of the blood pressure sensor (5) is 50-300 mmHg.
8. A synchronous analog simulation calibration method for blood pressure and reflective type photoelectric volume wave is characterized in that based on any one of claims 1 to 7, the synchronous analog simulation calibration device for blood pressure and reflective type photoelectric volume wave comprises,
the electric push rod (2) is controlled to periodically squeeze the simulated heart (3) to enable the simulated heart (3) to generate deformation, and red or tawny simulated blood in the simulated heart (3) is pushed into the simulated blood vessel to generate pulsating blood flow;
measuring directly the simulated blood pressure in the simulated blood vessel by means of a blood pressure sensor (5);
periodic volume change caused by pulsating blood flow in a simulated blood vessel is respectively detected through the reflective photoelectric volume wave sensors on the outer sides of the two simulated forearms (13), and the local instantaneous pulse wave conduction velocity is determined and the blood pressure information related to the pulse wave conduction velocity is obtained according to the time delay between the reflective photoelectric volume wave waveform characteristic points respectively detected by the two sensors;
and comparing the synchronously acquired simulated blood pressure with the blood pressure information based on the pulse wave conduction velocity to realize synchronous simulation calibration of the blood pressure and the reflective photoelectric volume wave.
9. The synchronous analog simulation calibration method for blood pressure and reflection type photoelectric volume waves according to claim 8, further comprising,
the gas pressure information in the cuff (10) is detected by using a commercial cuff type electronic sphygmomanometer, the non-invasive blood pressure is measured by an indirect method according to a non-invasive cuff type blood pressure measuring method,
and comparing the noninvasive blood pressure acquired synchronously with the blood pressure information based on the pulse wave conduction velocity to realize synchronous analog simulation calibration of the blood pressure and the reflective photoelectric volume wave.
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