CN107126201A - Continuous blood pressure detection method, equipment and the device of non-invasive - Google Patents

Continuous blood pressure detection method, equipment and the device of non-invasive Download PDF

Info

Publication number
CN107126201A
CN107126201A CN201710212408.9A CN201710212408A CN107126201A CN 107126201 A CN107126201 A CN 107126201A CN 201710212408 A CN201710212408 A CN 201710212408A CN 107126201 A CN107126201 A CN 107126201A
Authority
CN
China
Prior art keywords
user
pulse wave
time
radio frequency
blood pressure
Prior art date
Application number
CN201710212408.9A
Other languages
Chinese (zh)
Inventor
王尧
陈驰
张毅
朱宇东
Original Assignee
悦享趋势科技(北京)有限责任公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 悦享趋势科技(北京)有限责任公司 filed Critical 悦享趋势科技(北京)有限责任公司
Priority to CN201710212408.9A priority Critical patent/CN107126201A/en
Publication of CN107126201A publication Critical patent/CN107126201A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/02108Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
    • A61B5/02125Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics of pulse wave propagation time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/022Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers

Abstract

The invention discloses continuous blood pressure detection method, equipment and the device of a kind of non-invasive.Wherein, this method includes:The signal of the first radio frequency sensor and the second radio frequency sensor is obtained, wherein, the first radio frequency sensor and the second radio frequency sensor are separately positioned on the position of the different superficial artery of user two;According to signal acquisition pulse wave translation time, wherein, pulse wave translation time is used for the pressure value that user is obtained according to predetermined manner;Inflatable cuff pressurization is controlled to obtain user's blood pressure of inflatable cuff measurement;Predetermined manner is calibrated according to user's blood pressure and pulse ripple conduction time;The pressure value of user is measured using the predetermined manner after pulse wave translation time and calibration.There is the inaccurate technical problem of measurement result in the continuous BP measurement technology that the present invention solves existing non-invasive.

Description

Continuous blood pressure detection method, equipment and the device of non-invasive

Technical field

The present invention relates to bio signal detection field, in particular to a kind of continuous blood pressure detection side of non-invasive Method, equipment and device.

Background technology

Blood pressure under the measurable personal daily animation of continuous BP measurement function, is studied, continuously according to medical field Blood pressure measurement can more accurate, more fully reflect the blood pressure overall condition of a people.Such as carry out an ambulatory blood pressure prison round the clock Survey, it can also be appreciated that the variation tendency of blood pressure.Including decline situation of the blood pressure at night, rising condition when from morning, and one The overall variability situation of middle blood pressure round the clock.Continuous BP measurement has turned into hypertension and has managed indispensable detection means, is used for The identification and diagnosis of hypertension, for assessing cardiovascular and cerebrovascular risk, the effect for assessing Treatment of Hypertension.

Wide variety of current non-invasive blood pressure measurement is the measurement of cuff type sphygmomanometer, and measuring method common are manually Operation measures two kinds based on Korotkoff's Sound measurement and electronic system by oscillographic method, and Korotkoff's Sound mensuration is accepted extensively by medical domain But need trained personnel to operate, oscillographic method uses simple but there may be on some crowds larger error.Either Which kind of above-mentioned method, is required for cuff inflation to pressurize due to measuring each time, and pressurization can cause the discomfort of user, frequently pressurization The sensation of discomfort can be aggravated, while causing certain influence on blood pressure measurement precision.Particularly, at 24 hours, continuous ambulatory blood pressure was surveyed In amount, medically advise measurement on every 20 minutes of daytime once, every 30 minutes of night measured once, such pressurization measurement frequency pair It is larger in the influence of user's daily life, sleep quality.

It is theoretical with reference to related academic research from Moens-Korteweg equations in non-cuff type blood pressure measurement field On give mathematical relationship between pulse wave translation time PTT and blood pressure.According to theory analysis, when human vas foundation elasticity Modulus E0 does not occur under conditions of several hypotheses establishments such as significant changes, by calibration, can realize one by PTT measurements The blood pressure determined under precision is calculated.Electrocardio (ECG)+capillary photoelectricity volume ripple is typically used based on this theoretical product (PPG) method of synchro measure calculates PTT.These methods, the shortcoming of product have the following aspects:A) PTT calculates blood pressure and existed Academicly there is precondition, calibration process can only ensure accurately to push away when significant changes do not occur for key physiological parameters Blood pressure is calculated, if significant changes occur for physiological parameter, sphygmomanometer, which calculates accuracy rate, to be declined;B) using the product of these methods Comprising PTT measuring apparatus, user needs to use cuff type blood pressure measuring to take blood pressure and provides calibration data, and equipment can not be led in itself It is dynamic to initiate calibration, it is impossible to ensure precision;C) this kind of product measurement is that PTT is not exact value.Within a cardiac cycle, ventricle At the time of aorta petal is opened, blood is shot up, and artery starts vibrations and forms pulse wave.Therefore surveyed in heart+distal pulse ripple In ripple conduction time PTT system of feeling one's pulse, at the time of PTT zequins should be that ventricle aorta petal is opened.But, in order to Convenience is measured, existing product is used as time measurement zequin using electrocardiosignal R peaks mostly.The time so measured is pulse Ripple arrival time PAT, i.e., from electrocardiosignal R peaks to the time difference of pulse wave characteristic point, rather than accurate pulse wave translation time PTT.Because electrocardiosignal R peaks, which are not ventricle aortic valve, opens the moment, since electrocardiosignal R peaks to left ventricle Blood is penetrated, also one pre-ejection time, PEP is designated as.PAT=PEP+PTT, blood pressure is estimated using PAT as PTT approximation Error can be introduced.

To sum up, there is the inaccurate technical problem of measurement result in existing blood pressure measurement technology.

For it is above-mentioned the problem of, effective solution is not yet proposed at present.

The content of the invention

The embodiments of the invention provide continuous blood pressure detection method, equipment and the device of a kind of non-invasive, at least to solve There is the inaccurate technical problem of measurement result in the continuous BP measurement technology of certainly existing non-invasive.

One side according to embodiments of the present invention there is provided a kind of continuous blood pressure detection method of non-invasive, including: The signal of the first radio frequency sensor and the second radio frequency sensor is obtained, wherein, first radio frequency sensor and described second is penetrated Video sensor is separately positioned on the position of the different superficial artery of user two;During according to the signal acquisition pulse transit Between, wherein, the pulse wave translation time is used for the pressure value that the user is obtained according to predetermined manner;Control inflatable cuff Pressurize to obtain user's blood pressure of the inflatable cuff measurement;According to user's blood pressure and the pulse wave translation time pair The predetermined manner is calibrated;The user is measured using the predetermined manner after the pulse wave translation time and calibration Pressure value.

Further, the predetermined manner after using the pulse wave translation time and calibration measures the user's After continuous blood pressure, methods described also includes:When the time interval for carrying out the calibration meets predetermined interval, or, surveying Inflatable cuff pressurization is described inflatable to obtain when the pulse wave translation time measured occurs abnormal, then described in secondary control User's blood pressure of cuff measurement, obtains the current blood pressure of user;Utilize current blood pressure and current pulse the ripple conduction time pair The predetermined manner after calibration is calibrated again, and predetermined manner is calibrated again;Default side is calibrated again using described Formula and current pulse ripple conduction time measure the pressure value of the user.

Further, the calibration predetermined manner again and the current pulse ripple conduction time measurement user are being utilized After pressure value, methods described also includes:Compare the difference of the pressure value of the user and the current pressure value of the user;Sentence Whether the difference of breaking is less than or equal to predetermined threshold value;If it is judged that the difference is less than or equal to the default threshold Value, then extend the predetermined interval.

Further, obtaining the first radio frequency sensor and the signal of the second radio frequency sensor includes:Penetrated using described first Video sensor measures the signal of the upper arm arteria brachialis of the user;The pin of the user is measured using second radio frequency sensor The signal of superficial artery at ankle.

Further, included according to the signal acquisition pulse wave translation time:First radio frequency sensor is obtained to adopt Collect the subclavian artery signal of the user;Obtain the electrocardiosignal that EGC sensor measures the user;According to the clavicle Lower arterial signal and the electrocardiosignal obtain pulse wave arrival time;It regard the pulse wave arrival time as the pulse wave Conduction time.

Further, obtaining pulse wave translation time according to the signal and predetermined manner includes:Obtain heart sound transducer Measure the cardiechema signals of the user;According to the cardiechema signals, the electrocardiosignal and the subclavian artery signal acquisition The pre-ejection time;The pulse wave translation time is obtained according to the pulse wave arrival time and the pre-ejection time.

Another aspect according to embodiments of the present invention, additionally provides a kind of continuous blood pressure detection device of non-invasive, bag Include:First radio frequency sensor, the signal of the superficial artery for detecting user first position;Second radio frequency sensor, for examining The signal of the superficial artery of the user second place is surveyed, the second place is different from the first position;With pressure sensor Inflatable cuff, the blood pressure for measuring the user;Main control unit, respectively with first radio frequency sensor, described Two radio frequency sensors are connected with the inflatable cuff with pressure sensor, for according to first radio frequency sensor The signal and predetermined manner measured with second radio frequency sensor obtains pulse wave translation time, and according to the user's Blood pressure and the pulse wave translation time are calibrated to the predetermined manner, and utilize the pulse wave translation time and calibration The predetermined manner afterwards measures the pressure value of the user.

Further, the equipment also includes:EGC sensor, is connected with the main control unit, described for measuring The electrocardiosignal of user.

Further, the equipment also includes:Heart sound transducer, is connected with the main control unit, described for measuring The cardiechema signals of user.

Another aspect according to embodiments of the present invention, additionally provides a kind of continuous blood pressure detection means of non-invasive, bag Include:First acquisition unit, the signal for obtaining the first radio frequency sensor and the second radio frequency sensor, wherein, described first penetrates The position of video sensor and second radio frequency sensor superficial artery that to be separately positioned on user two different;Second obtains single Member, for according to the signal acquisition pulse wave translation time, wherein, the pulse wave translation time is used for according to predetermined manner Obtain the pressure value of the user;First control unit, for controlling inflatable cuff pressurization to obtain the inflatable cuff User's blood pressure of measurement;First alignment unit, for according to user's blood pressure and the pulse wave translation time to described pre- If mode is calibrated;First measuring unit, for utilizing the predetermined manner after the pulse wave translation time and calibration Measure the pressure value of the user.

Further, described device also includes:Second control unit, for utilizing the pulse wave translation time and school The predetermined manner after standard is measured after the continuous blood pressure of the user, meets default in the time interval for carrying out the calibration During interval, or, when the pulse wave translation time measured occurs abnormal, then inflatable cuff pressurization described in secondary control To obtain user's blood pressure of the inflatable cuff measurement, the current blood pressure of user is obtained;Second alignment unit, for utilizing State current blood pressure and current pulse ripple conduction time to calibrate the predetermined manner after calibration again, calibrated again Predetermined manner;Second measuring unit, utilizes the calibration predetermined manner again and the current pulse ripple conduction time measurement use The pressure value at family.

Further, described device also includes:Comparing unit, for calibrating predetermined manner again and current described in Pulse wave translation time is measured after the pressure value of the user, the pressure value and the current blood of the user of relatively more described user The difference of pressure value;Judging unit, for judging whether the difference is less than or equal to predetermined threshold value;Delay unit, for When judging that the difference is less than or equal to the predetermined threshold value, extend the predetermined interval.

Further, the first acquisition unit includes:First measurement module, for using first radio frequency sensor Measure the signal of the upper arm arteria brachialis of the user;Second measurement module, for measuring institute using second radio frequency sensor State the signal of superficial artery at the ankle of user.

Further, the second acquisition unit includes:First acquisition module, for obtaining first radio frequency sensor Gather the subclavian artery signal of the user;Second acquisition module, the heart of the user is measured for obtaining EGC sensor Electric signal;3rd acquisition module, when being reached for obtaining pulse wave according to the subclavian artery signal and the electrocardiosignal Between;Conduction time module, for regarding the pulse wave arrival time as the pulse wave translation time.

Further, the second acquisition unit includes:4th acquisition module, it is described for obtaining heart sound transducer measurement The cardiechema signals of user;5th acquisition module, for according to the cardiechema signals, the electrocardiosignal and the subclavian artery The signal acquisition pre-ejection time;6th acquisition module, during for according to the pulse wave arrival time and the pre-ejection Between obtain the pulse wave translation time.

In embodiments of the present invention, the arteriogram for measuring user using the first radio frequency sensor and the second radio frequency sensor is believed Number;According to arteriogram signal acquisition pulse wave translation time, wherein, pulse wave translation time, which is used to obtain according to predetermined manner, to be used The pressure value at family;And the mode of the inflatable cuff pressurization measurement user's pressure of control, pass through the use measured according to inflatable cuff Family blood pressure and pulse ripple conduction time is calibrated to predetermined manner, and utilizes the default side after pulse wave translation time and calibration Formula measures the pressure value of user, has reached the purpose that accurate user's pressure value is obtained using pulse wave translation time, so that real Show and the technique effect of blood pressure is accurately measured by non-invasive continuous BP measurement technology, and then solved existing non-intrusive There is the inaccurate technical problem of measurement result in the continuous BP measurement technology of formula.

Brief description of the drawings

Accompanying drawing described herein is used for providing a further understanding of the present invention, constitutes the part of the application, this hair Bright schematic description and description is used to explain the present invention, does not constitute inappropriate limitation of the present invention.In the accompanying drawings:

Fig. 1 is a kind of flow chart of the continuous blood pressure detection method of optional non-invasive according to embodiments of the present invention;

Fig. 2 is a kind of schematic diagram of the continuous blood pressure detection device of optional non-invasive according to embodiments of the present invention;

Fig. 3 is the schematic diagram of main control unit according to embodiments of the present invention;

Fig. 4 is the flow chart for the active calibration that main control unit according to embodiments of the present invention is performed;

Fig. 5 is a kind of schematic diagram of the continuous blood pressure detection means of optional non-invasive according to embodiments of the present invention.

Embodiment

In order that those skilled in the art more fully understand the present invention program, below in conjunction with the embodiment of the present invention Accompanying drawing, the technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is only The embodiment of a part of the invention, rather than whole embodiments.Based on the embodiment in the present invention, ordinary skill people The every other embodiment that member is obtained under the premise of creative work is not made, should all belong to the model that the present invention is protected Enclose.

It should be noted that term " first " in description and claims of this specification and above-mentioned accompanying drawing, " Two " etc. be for distinguishing similar object, without for describing specific order or precedence.It should be appreciated that so using Data can exchange in the appropriate case, so as to embodiments of the invention described herein can with except illustrating herein or Order beyond those of description is implemented.In addition, term " comprising " and " having " and their any deformation, it is intended that cover Lid is non-exclusive to be included, for example, the process, method, system, product or the equipment that contain series of steps or unit are not necessarily limited to Those steps or unit clearly listed, but may include not list clearly or for these processes, method, product Or the intrinsic other steps of equipment or unit.

According to embodiments of the present invention there is provided a kind of embodiment of the method for the continuous blood pressure detection method of non-invasive, need It is noted that the step of the flow of accompanying drawing is illustrated can such as one group computer executable instructions computer system It is middle perform, and, although logical order is shown in flow charts, but in some cases, can be with different from herein Order performs shown or described step.

Fig. 1 is a kind of flow chart of the continuous blood pressure detection method of optional non-invasive according to embodiments of the present invention, As shown in figure 1, this method comprises the following steps:

Step S101, obtains the signal of the first radio frequency sensor and the second radio frequency sensor, wherein, the first radio frequency sensor With the position of the second radio frequency sensor superficial artery that to be separately positioned on user two different;

The pulse wave signal that the first radio frequency sensor and the second radio frequency sensor are measured is obtained, wherein, the first radio frequency is passed Sensor and the second radio frequency sensor are separately positioned on two different positions of user's body, and the position must be user's body There is the position of superficial artery on body, so that the first radio frequency sensor and the second radio frequency sensor measure the different pulse of two-way Ripple signal.

Alternatively, obtaining the first radio frequency sensor and the signal of the second radio frequency sensor includes:Using the first radio frequency sensing The signal of the upper arm arteria brachialis of device measurement user;The letter of superficial artery at the ankle of user is measured using the second radio frequency sensor Number.

Alternatively, the first radio frequency sensor is arranged on to the skin surface of the upper arm arteria brachialis of user, the measurement upper arm upper arm is moved The pulse wave signal of arteries and veins, the second radio frequency sensor is arranged on the skin surface of superficial artery at the ankle of user, measures ankle Locate the pulse wave signal of superficial artery, the different pulse wave of two-way is obtained by the first radio frequency sensor and the second radio frequency sensor Signal.

Step S102, according to signal acquisition pulse wave translation time, wherein, pulse wave translation time is used for according to default side Formula obtains the pressure value of user;

The different pulse wave signal of the two-way that is measured according to the first radio frequency sensor and the second radio frequency sensor, obtains arteries and veins Fight ripple conduction time, wherein, pulse wave translation time is conduction time of the pulse wave between two points of arteries, according to pre- If mode can obtain the pressure value of user according to pulse wave translation time.

Step S103, controls inflatable cuff pressurization to obtain user's blood pressure of inflatable cuff measurement;

Control inflatable cuff inflation to pressurize, user's blood pressure is obtained by inflating cuff measurement.

Step S104, is calibrated according to user's blood pressure and pulse ripple conduction time to predetermined manner;

The user's blood pressure and pulse ripple conduction time obtained according to inflatable cuff measurement, to above-mentioned according to pulse transit The predetermined manner that time obtains the pressure value of user is calibrated, the predetermined manner after being calibrated.Filled by inflatable cuff The blood pressure of gas pressurization measurement user, it is more accurate to obtain user's blood pressure measurement, by the measurement result with being passed using pulse wave The pressure value for leading the user that the time obtains according to predetermined manner is compared, and predetermined manner is calibrated, can effectively be carried The accuracy for the family blood pressure measurement that usury is got with pulse wave translation time.Although it should be noted that by that can fill User's blood pressure measurement that gas cuff measurement is obtained is more accurate, but passes through the blood of inflatable cuff inflation pressurization measurement user Pressure can cause certain sense of discomfort to user, therefore, in embodiments of the present invention, not use inflatable cuff frequently to measure user Blood pressure, only measures the blood pressure of user when required by inflatable cuff, and above-mentioned predetermined manner is carried out using its measurement result Calibration.

Step S105, the pressure value of user is measured using the predetermined manner after pulse wave translation time and calibration.

It is measurable to obtain accurate user's blood pressure according to pulse wave translation time, and according to the predetermined manner after calibration Value.

In embodiments of the present invention, the arteriogram for measuring user using the first radio frequency sensor and the second radio frequency sensor is believed Number;According to arteriogram signal acquisition pulse wave translation time, wherein, pulse wave translation time, which is used to obtain according to predetermined manner, to be used The pressure value at family;And the mode of the inflatable cuff pressurization measurement user's pressure of control, pass through the use measured according to inflatable cuff Family blood pressure and pulse ripple conduction time is calibrated to predetermined manner, and utilizes the default side after pulse wave translation time and calibration Formula measures the pressure value of user, has reached the purpose that accurate user's pressure value is obtained using pulse wave translation time, so that real Showed and the technique effect of blood pressure accurately measured by the continuous BP measurement technology of non-invasive, so solve it is existing it is non-enter There is the inaccurate technical problem of measurement result in the continuous BP measurement technology for invading formula.

Alternatively, after the continuous blood pressure of the predetermined manner measurement user after using pulse wave translation time and calibration, Method also includes:When the time interval calibrated meets predetermined interval, or, in the pulse wave translation time hair measured When raw abnormal, then the inflatable cuff of secondary control pressurizes to obtain user's blood pressure of inflatable cuff measurement, obtains the current of user Blood pressure;The predetermined manner after calibration is calibrated again using current blood pressure and current pulse ripple conduction time, obtained again Calibrate predetermined manner;The pressure value of user is measured using calibration predetermined manner again and current pulse ripple conduction time.

The physiological parameter of user can change with the time, the standard of the user's pressure value obtained according to pulse wave translation time True property can also be decreased, in order to ensure the accuracy of the user's blood value obtained according to pulse wave translation time, to above-mentioned pre- If the time interval that mode is calibrated meets predetermined interval, inflatable cuff inflation pressurization is controlled to enter the pressure value of user Row is measured, and the current pressure value obtained using measurement is calibrated again to above-mentioned predetermined manner;Or, though the time interval of calibration Do not meet predetermined interval, but the pulse wave translation time measured is when occurring obvious anomalous variation, is measured by inflating cuff User's pressure value is simultaneously calibrated again to above-mentioned predetermined manner.After the completion of calibration, pressed using the pulse wave translation time currently measured The pressure value of user is measured according to the predetermined manner after calibrating again.

For example:Predetermined interval can be set to 4 hours, if current time reaches apart from the time interval of previous calibration To 4 hours, then control inflatable cuff inflation to pressurize, user's blood pressure is measured, and using measurement result to above-mentioned pre- If mode is recalibrated;If current time not yet reaches 4 hours apart from the time interval of previous calibration, but currently obtain Pulse wave translation time compared with the pulse wave translation time got before, occur significant change, then control inflatable sleeve Band inflating pressure, is measured to user's blood pressure, and above-mentioned predetermined manner is recalibrated using measurement result.

Alternatively, using again calibration predetermined manner and current pulse ripple conduction time measurement user pressure value it Afterwards, method also includes:Compare the difference of the pressure value of user and the current pressure value of user;Judge whether difference is less than or waits In predetermined threshold value;If it is judged that difference is less than or equal to predetermined threshold value, then extend predetermined interval.

In embodiments of the present invention, be also provided with the condition of delay calibration, i.e., will be by inflatable after calibrating again The pressure value that cuff measurement is obtained is carried out with the pressure value obtained according to the predetermined manner before calibration according to pulse wave translation time Compare, obtain the difference of the two, if the difference is less than or equal to predetermined threshold value, between what extension triggering was calibrated again presets Every.

Alternatively, included according to signal acquisition pulse wave translation time:Obtain the lock that the first radio frequency sensor gathers user Arterial signal under bone;Obtain the electrocardiosignal that EGC sensor measures user;Obtained according to subclavian artery signal and electrocardiosignal Take pulse wave arrival time;It regard pulse wave arrival time as pulse wave translation time.

In embodiments of the present invention, the pulse wave signal that can also be obtained according to measurement, obtains pulse otherwise Ripple conduction time.Specifically, user's subclavian artery signal is gathered by the first radio frequency sensor, and passes through EGC sensor Measurement obtains the electrocardiosignal of user, and pulse wave arrival time (electrocardio is got according to subclavian artery signal and electrocardiosignal Time of the signal R peaks to PPG wave character points), because pulse wave arrival time is approximately equal with pulse wave translation time, because This, regard pulse wave arrival time as pulse wave translation time.

Alternatively, obtaining pulse wave translation time according to signal and predetermined manner includes:Heart sound transducer measurement is obtained to use The cardiechema signals at family;According to cardiechema signals, electrocardiosignal and subclavian artery signal acquisition pre-ejection time;According to pulse wave Arrival time and pre-ejection time obtain pulse wave translation time.

Above-mentioned pulse wave arrival time and pulse wave translation time are only approximately equals, and pulse wave arrival time is actual to be equal to Pre-ejection time and pulse wave translation time sum, alternatively, in order to further improve the pulse wave translation time got Precision, by heart sound transducer measure user cardiechema signals, according to cardiechema signals, electrocardiosignal and subclavian artery believe Number the pre-ejection time is obtained, the difference of pulse wave arrival time and pre-ejection time are pulse wave translation time.

According to embodiments of the present invention, a kind of continuous blood pressure detection device of non-invasive is additionally provided, Fig. 2 is according to this hair The flow chart of the continuous blood pressure detection method of a kind of optional non-invasive of bright embodiment, as shown in Fig. 2 the equipment includes:

First radio frequency sensor, the signal of the superficial artery for detecting user first position;

Second radio frequency sensor, the signal of the superficial artery for detecting the user second place, the second place with first Put difference;

Inflatable cuff with pressure sensor, the blood pressure for measuring user;

Main control unit, respectively with the first radio frequency sensor, the second radio frequency sensor and with the inflatable of pressure sensor Cuff is connected, for obtaining arteries and veins according to the first radio frequency sensor and the signal and predetermined manner of the measurement of the second radio frequency sensor Fight ripple conduction time, and predetermined manner is calibrated according to the blood pressure and pulse ripple conduction time of user, and utilize pulse wave Predetermined manner after conduction time and calibration measures the pressure value of user.

In the continuous blood pressure detection device for the non-invasive that the embodiment of the present invention is provided, the first radio frequency sensor and Two radio frequency sensors are used for the superficial arterial signal for measuring user, wherein, the first radio frequency sensor and the second radio frequency sensor point Two different positions of user's body are not arranged on, and the position must be the position that there is superficial artery on user's body Put, so that the first radio frequency sensor and the second radio frequency sensor measure the different superficial arterial signal of two-way.Passed with pressure The inflatable cuff of sensor is used for the blood pressure for measuring user.Main control unit and the first radio frequency sensor, the second radio frequency sensor and Inflatable cuff with pressure sensor is connected, and is measured by the first radio frequency sensor of acquisition and the second radio frequency sensor The different shallow artery signal of two-way, according to shallow artery signal acquisition pulse wave translation time;Obtain with pressure sensor can User's blood pressure of cuff measurement is inflated, according to the blood pressure to the predetermined manner according to pulse wave translation time acquisition user's pressure value Calibrated, so that the predetermined manner after being calibrated.Main control unit, according to the predetermined manner after calibration, you can utilize pulse Ripple conduction time continuously acquires the pressure value of user.

It should be noted that the user's blood pressure measurement obtained by inflatable cuff measurement is more accurate, but pass through The blood pressure of inflatable cuff inflation pressurization measurement user can cause certain sense of discomfort to user, therefore, in the embodiment of the present invention In, do not use inflatable cuff frequently to measure user's blood pressure, the blood pressure of user, profit are only measured when required by inflatable cuff Above-mentioned predetermined manner is calibrated with its measurement result.

In embodiments of the present invention, the arteriogram for measuring user using the first radio frequency sensor and the second radio frequency sensor is believed Number;According to arteriogram signal acquisition pulse wave translation time, wherein, pulse wave translation time, which is used to obtain according to predetermined manner, to be used The pressure value at family;And the mode of the inflatable cuff pressurization measurement user's pressure of control, pass through the use measured according to inflatable cuff Family blood pressure and pulse ripple conduction time is calibrated to predetermined manner, and utilizes the default side after pulse wave translation time and calibration Formula measures the pressure value of user, has reached the purpose that accurate user's pressure value is obtained using pulse wave translation time, so that real Show and the technique effect of blood pressure is accurately measured by non-invasive continuous BP measurement technology, and then solved existing non-intrusive There is the inaccurate technical problem of measurement result in the continuous BP measurement technology of formula.

Alternatively, equipment also includes:EGC sensor, is connected with main control unit, the electrocardiosignal for measuring user.

In embodiments of the present invention, pulse wave translation time can also be obtained otherwise, and specifically, the present invention is real The continuous blood pressure detection device for applying the non-invasive that example is provided also includes EGC sensor, and the electrocardio for measuring user is believed Number, EGC sensor is connected with main control unit, and main control unit obtains electrocardiosignal and the radio frequency biography that EGC sensor is measured The superficial arterial signal that sensor is measured, and pulse wave arrival time is obtained according to electrocardiosignal and superficial arterial signal, due to Therefore pulse wave arrival time, can regard pulse wave arrival time as pulse wave approximately equal with pulse wave translation time Conduction time.

Alternatively, equipment also includes:Heart sound transducer, is connected with main control unit, the cardiechema signals for measuring user.

Alternatively, in order to further improve the precision of the pulse wave translation time got, the embodiment of the present invention is provided The continuous blood pressure detection device of non-invasive include sensor between electricity, pass through heart sound transducer and measure the heart sound of user and believe Number, according to cardiechema signals, electrocardiosignal and subclavian artery signal acquisition pre-ejection time, pulse wave arrival time is with penetrating The difference of blood early stage time is pulse wave translation time.

Alternatively, in embodiments of the present invention, in order to preferably realize various functions as above, above-mentioned main control unit includes Multiple functional modules, as shown in figure 3, above-mentioned main control unit includes:First functional module and the second functional module, wherein, first Functional module is used to open oscillographic method blood pressure measurement, that is, controls the blood pressure of inflatable cuff inflation pressurization measurement user;Second work( Energy module is used to be acquired sensor signal.Specifically, the first functional module is opened the first radio frequency sensor and second and penetrated Video sensor, acquisition first keeps pouring in sensor and second and keeps pouring in the signal for the shallow artery that sensor is measured;First functional module control Inflatable cuff pressurization inflation is made, the blood pressure of user is measured.

Alternatively, main control module also include the 3rd functional module and the 4th functional module, wherein, the 3rd functional module according to The two-way shallow artery signal acquisition pulse wave translation time that first functional module is obtained, the 4th functional module is according to the second function mould The user's blood pressure measured by inflatable cuff that block is got is calibrated to predetermined manner, and wherein predetermined manner is according to pulse Ripple conduction time obtains the predetermined manner of user's blood pressure, and after the completion of calibration, the 4th functional module is according to the default side after calibration Formula, the pressure value of user is obtained according to pulse wave translation time.

In embodiments of the present invention, user's blood pressure is measured using inflatable cuff, the pressure value obtained according to measurement is to root The predetermined manner for obtaining user's pressure value according to pulse wave translation time carries out active calibration, so as to improve according to pulse transit The degree of accuracy for user's pressure value that time obtains.

With reference to Fig. 4 to performed by main control unit in the continuous blood pressure detection device of the non-invasive of the embodiment of the present invention Active calibration flow illustrate, as shown in figure 4, the flow comprises the following steps:

Step S401, the second functional module obtains sensor measurement signal.

First radio frequency sensor and the second radio frequency sensor are separately positioned on to two different positions of user's body, and And the position must be the position that there is superficial artery on user's body, so as to the first radio frequency sensor and the second radio frequency sensor Measure the different superficial arterial signal of two-way.Alternatively, sensor measurement signal also includes the electrocardio that EGC sensor is measured Signal, and the cardiechema signals that heart sound transducer is measured.

Step S402, the 3rd functional module obtains pulse wave translation time according to sensor measurement signal.

3rd functional module is according to the different shallow artery of the two-way of the first radio frequency sensor and the measurement of the second radio frequency sensor Signal acquisition pulse wave translation time.Alternatively, the shallow artery signal that the 3rd functional module is measured according to the first radio frequency sensor And electrocardiosignal, PAT is obtained, and regard PAT as pulse wave translation time.Alternatively, passed to improve the pulse wave got The precision of time is led, the 3rd functional module obtains the pre-ejection time according to cardiechema signals, and according to PAT and pre-ejection time Obtain pulse wave translation time.

Step S403, judges whether to meet calibration condition.

Specifically, if the current first time measurement being measured as in continuous blood pressure measuring, meets calibration condition;If worked as The preceding moment reaches predetermined interval apart from the time interval that last time calibrates, then meets calibration condition;If currently surveyed according to sensor Obvious exception occurs for the pulse wave translation time for measuring signal acquisition, then meets calibration condition.

Step S404, if meeting calibration condition by judgement, the first functional module controls inflatable cuff pressurization to survey Measure user's pressure value.

Step S405, the 4th functional module according to user's pressure value and pulse transit enter between complete predetermined manner calibrate.

By inflating the blood pressure of cuff inflation pressurization measurement user, it is more accurate to obtain user's blood pressure measurement, by this The pressure value of user of the measurement result with being obtained using pulse wave translation time according to predetermined manner is compared, to predetermined manner Calibrated, can effectively improve the accuracy of the family blood pressure measurement got using pulse wave translation time.

Step S406, the 4th functional module obtains user's blood pressure according to pulse wave translation time and predetermined manner.

The active school of the predetermined manner to obtaining user's pressure value according to pulse wave translation time is completed by above-mentioned steps The measurement of accurate and pressure value.

According to embodiments of the present invention, a kind of continuous blood pressure detection means of non-invasive is additionally provided, Fig. 5 is according to this hair The schematic diagram of the continuous blood pressure detection means of a kind of optional non-invasive of bright embodiment, as shown in figure 5, the device includes:

First acquisition unit 510, the signal for obtaining the first radio frequency sensor and the second radio frequency sensor, wherein, the One radio frequency sensor and the second radio frequency sensor are separately positioned on the position of the different superficial artery of user two.

First acquisition unit 510 obtains the pulse wave signal that the first radio frequency sensor and the second radio frequency sensor are measured, Wherein, the first radio frequency sensor and the second radio frequency sensor are separately positioned on two different positions of user's body, and should Position must be the position that there is superficial artery on user's body, so as to the first radio frequency sensor and the measurement of the second radio frequency sensor To the different pulse wave signal of two-way.

Alternatively, first acquisition unit includes:First measurement module, for measuring user's using the first radio frequency sensor The signal of upper arm arteria brachialis;Superficial artery at second measurement module, the ankle for measuring user using the second radio frequency sensor Signal.

Alternatively, the first radio frequency sensor is arranged on to the skin surface of the upper arm arteria brachialis of user, the first measurement module The pulse wave signal of upper arm arteria brachialis is measured, the second radio frequency sensor is arranged on to the skin table of superficial artery at the ankle of user The pulse wave signal of superficial artery, is passed by the first radio frequency sensor and the second radio frequency at face, the second measurement module measurement ankle Sensor obtains the different pulse wave signal of two-way.

Second acquisition unit 520, for according to signal acquisition pulse wave translation time, wherein, pulse wave translation time is used In the pressure value that user is obtained according to predetermined manner.

The different arteries and veins of two-way that second acquisition unit 520 is measured according to the first radio frequency sensor and the second radio frequency sensor Fight ripple signal, obtain pulse wave translation time, wherein, pulse wave translation time is pulse wave between two points of arteries Conduction time, the pressure value of user can be obtained according to predetermined manner according to pulse wave translation time.

First control unit 530, user's blood pressure of inflatable cuff measurement is obtained for controlling inflatable cuff pressurization.

First control unit 530 controls inflatable cuff inflation to pressurize, and user's blood pressure is obtained by inflating cuff measurement.

First alignment unit 540, for being calibrated according to user's blood pressure and pulse ripple conduction time to predetermined manner;

User's blood pressure and pulse ripple conduction time that first alignment unit 540 is obtained according to inflation cuff measurement, to above-mentioned The predetermined manner that the pressure value of user is obtained according to pulse wave translation time is calibrated, the predetermined manner after being calibrated.It is logical The blood pressure of gas overcharging cuff inflation pressurization measurement user, it is more accurate to obtain user's blood pressure measurement, by the measurement result with The pressure value of the user obtained using pulse wave translation time according to predetermined manner is compared, and predetermined manner is calibrated, The accuracy of the family blood pressure measurement got using pulse wave translation time can effectively be improved.It should be noted that Although the user's blood pressure measurement obtained by inflatable cuff measurement is more accurate, by inflating cuff inflation pressurization survey The blood pressure of amount user can cause certain sense of discomfort to user, therefore, in embodiments of the present invention, not use inflation cuff frequent User's blood pressure is measured, the blood pressure of user is only measured when required by inflation cuff, using its measurement result to above-mentioned default side Formula is calibrated.

First measuring unit 550, the blood for measuring user using the predetermined manner after pulse wave translation time and calibration Pressure value.

First measuring unit 550 is measurable to obtain standard according to the predetermined manner after calibration according to pulse wave translation time True user's pressure value.

In embodiments of the present invention, the arteriogram for measuring user using the first radio frequency sensor and the second radio frequency sensor is believed Number;According to arteriogram signal acquisition pulse wave translation time, wherein, pulse wave translation time, which is used to obtain according to predetermined manner, to be used The pressure value at family;And the mode of the inflatable cuff pressurization measurement user's pressure of control, pass through the use measured according to inflatable cuff Family blood pressure and pulse ripple conduction time is calibrated to predetermined manner, and utilizes the default side after pulse wave translation time and calibration Formula measures the pressure value of user, has reached the purpose that accurate user's pressure value is obtained using pulse wave translation time, so that real Show and the technique effect of blood pressure is accurately measured by non-invasive continuous BP measurement technology, and then solved existing non-intrusive There is the inaccurate technical problem of measurement result in the continuous BP measurement technology of formula.

Alternatively, device also includes:Second control unit, for default after using pulse wave translation time and calibration Mode is measured after the continuous blood pressure of user, when the time interval calibrated meets predetermined interval, or, what is measured When pulse wave translation time occurs abnormal, then the inflatable cuff of secondary control pressurizes to obtain user's blood of inflatable cuff measurement Pressure, obtains the current blood pressure of user;Second alignment unit, for utilizing current blood pressure and current pulse ripple conduction time to calibration Predetermined manner afterwards is calibrated again, and predetermined manner is calibrated again;Second measuring unit, it is default square using calibrating again Formula and current pulse ripple conduction time measure the pressure value of user.

The physiological parameter of user can change with the time, the standard of the user's pressure value obtained according to pulse wave translation time True property can also be decreased, in order to ensure the accuracy of the user's blood value obtained according to pulse wave translation time, to above-mentioned pre- If the time interval that mode is calibrated meets predetermined interval, the second control unit control the pressurization of inflatable cuff inflation to The pressure value at family is measured, and the second alignment unit is using the obtained current pressure value of measurement to above-mentioned predetermined manner school again It is accurate;Or, though the time interval of calibration does not meet predetermined interval, the pulse wave translation time measured occurs obvious abnormal During change, the second control unit inflation cuff inflation measurement user's pressure value, the second alignment unit to above-mentioned predetermined manner again Calibration.After the completion of calibration, the second measuring unit fights ripple conduction time according to default after calibrating again using the fat currently measured Mode measures the pressure value of user.

For example:Predetermined interval can be set to 4 hours, if current time reaches apart from the time interval of previous calibration To 4 hours, then control inflatable cuff inflation to pressurize, user's blood pressure is measured, and using measurement result to above-mentioned pre- If mode is recalibrated;If current time not yet reaches 4 hours apart from the time interval of previous calibration, but currently obtain Pulse wave translation time compared with the pulse wave translation time got before, occur significant change, then control inflatable sleeve Band inflating pressure, is measured to user's blood pressure, and above-mentioned predetermined manner is recalibrated using measurement result.

Alternatively, device also includes:Comparing unit, for utilizing calibration predetermined manner again and the conduction of current pulse ripple After the pressure value of time measurement user, compare the difference of the pressure value of user and the current pressure value of user;Judging unit, is used In judge difference whether be less than or equal to predetermined threshold value;Delay unit, for judging that it is default that difference is less than or equal to During threshold value, extend predetermined interval.

In embodiments of the present invention, the condition of delay calibration is also provided with, i.e., after calibrating again, comparing unit will be logical Cross the pressure value that inflatable cuff measurement is obtained and the blood obtained according to the predetermined manner before calibration according to pulse wave translation time Pressure value is compared, and obtains the difference of the two, and the judging unit difference is judged, is preset if the difference is less than or equal to Threshold value, the then predetermined interval that extension triggering is calibrated again.

Alternatively, second acquisition unit includes:First acquisition module, for obtaining the first radio frequency sensor collection user's Subclavian artery signal;Second acquisition module, the electrocardiosignal of user is measured for obtaining EGC sensor;3rd obtains mould Block, for obtaining PAT according to subclavian artery signal and electrocardiosignal;Conduction time module, for being passed PAT as pulse wave Lead the time.

In embodiments of the present invention, the pulse wave signal that can also be obtained according to measurement, obtains pulse otherwise Ripple conduction time.Specifically, the first acquisition module obtains user's subclavian artery signal of the first radio frequency sensor collection, second Acquisition module obtains the electrocardiosignal of the user of EGC sensor measurement, and the 3rd acquisition module is according to subclavian artery signal and the heart Electric signal gets pulse wave arrival time (time of the electrocardiosignal R peaks to PPG wave character points), when being reached due to pulse wave Between can be approximately equal with pulse wave translation time, therefore, conduction time module regard pulse wave arrival time as pulse wave Conduction time.

Alternatively, second acquisition unit includes:4th acquisition module, the heart sound of user is measured for obtaining heart sound transducer Signal;5th acquisition module, for according to cardiechema signals, electrocardiosignal and subclavian artery signal acquisition pre-ejection time; 6th acquisition module, for obtaining pulse wave translation time according to pulse wave arrival time and pre-ejection time.

Above-mentioned PAT and pulse wave translation time are only approximately equals, pulse wave arrival time it is actual equal to pre-ejection when Between with pulse wave translation time sum, alternatively, in order to further improve the precision of the pulse wave translation time got, the 4th Acquisition module obtains the cardiechema signals of the user of heart sound transducer measurement, and the 5th acquisition module is according to cardiechema signals, electrocardiosignal And the subclavian artery signal acquisition pre-ejection time, when the 6th acquisition module obtains pulse wave arrival time with pre-ejection Between difference, the difference is pulse wave translation time.

The embodiments of the present invention are for illustration only, and the quality of embodiment is not represented.

In the above embodiment of the present invention, the description to each embodiment all emphasizes particularly on different fields, and does not have in some embodiment The part of detailed description, may refer to the associated description of other embodiment.

In several embodiments provided herein, it should be understood that disclosed technology contents, others can be passed through Mode is realized.Wherein, device embodiment described above is only schematical, such as division of described unit, Ke Yiwei A kind of division of logic function, can there is other dividing mode when actually realizing, such as multiple units or component can combine or Person is desirably integrated into another system, or some features can be ignored, or does not perform.Another, shown or discussed is mutual Between coupling or direct-coupling or communication connection can be the INDIRECT COUPLING or communication link of unit or module by some interfaces Connect, can be electrical or other forms.

The unit illustrated as separating component can be or may not be it is physically separate, it is aobvious as unit The part shown can be or may not be physical location, you can with positioned at a place, or can also be distributed to multiple On unit.Some or all of unit therein can be selected to realize the purpose of this embodiment scheme according to the actual needs.

In addition, each functional unit in each embodiment of the invention can be integrated in a processing unit, can also That unit is individually physically present, can also two or more units it is integrated in a unit.Above-mentioned integrated list Member can both be realized in the form of hardware, it would however also be possible to employ the form of SFU software functional unit is realized.

If the integrated unit is realized using in the form of SFU software functional unit and as independent production marketing or used When, it can be stored in a computer read/write memory medium.Understood based on such, technical scheme is substantially The part contributed in other words to prior art or all or part of the technical scheme can be in the form of software products Embody, the computer software product is stored in a storage medium, including some instructions are to cause a computer Equipment (can for personal computer, server or network equipment etc.) perform each embodiment methods described of the invention whole or Part steps.And foregoing storage medium includes:USB flash disk, read-only storage (ROM, Read-Only Memory), arbitrary access are deposited Reservoir (RAM, Random Access Memory), mobile hard disk, magnetic disc or CD etc. are various can be with store program codes Medium.

Described above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should It is considered as protection scope of the present invention.

Claims (15)

1. a kind of continuous blood pressure detection method of non-invasive, it is characterised in that including:
The signal of the first radio frequency sensor and the second radio frequency sensor is obtained, wherein, first radio frequency sensor and described Two radio frequency sensors are separately positioned on the position of the different superficial artery of user two;
According to the signal acquisition pulse wave translation time, wherein, the pulse wave translation time is used to obtain according to predetermined manner Take the pressure value of the user;
Inflatable cuff pressurization is controlled to obtain user's blood pressure of the inflatable cuff measurement;
The predetermined manner is calibrated according to user's blood pressure and the pulse wave translation time;
The pressure value of the user is measured using the predetermined manner after the pulse wave translation time and calibration.
2. according to the method described in claim 1, it is characterised in that the institute after using the pulse wave translation time and calibration State after the continuous blood pressure that predetermined manner measures the user, methods described also includes:
When the time interval for carrying out the calibration meets predetermined interval, or, in the pulse wave translation time measured When generation is abnormal, then inflatable cuff described in secondary control pressurizes to obtain user's blood pressure of the inflatable cuff measurement, obtains The current blood pressure of user;
The predetermined manner after calibration is calibrated again using current blood pressure and current pulse the ripple conduction time, obtained To calibrating predetermined manner again;
The pressure value of the user is measured using the calibration predetermined manner again and current pulse ripple conduction time.
3. method according to claim 2, it is characterised in that calibrating predetermined manner and current pulse again described in Ripple conduction time is measured after the pressure value of the user, and methods described also includes:
Compare the difference of the pressure value of the user and the current pressure value of the user;
Judge whether the difference is less than or equal to predetermined threshold value;
If it is judged that the difference is less than or equal to the predetermined threshold value, then extend the predetermined interval.
4. according to the method described in claim 1, it is characterised in that obtain the first radio frequency sensor and the second radio frequency sensor Signal includes:
The signal of the upper arm arteria brachialis of the user is measured using first radio frequency sensor;
The signal of superficial artery at the ankle of the user is measured using second radio frequency sensor.
5. according to the method described in claim 1, it is characterised in that included according to the signal acquisition pulse wave translation time:
Obtain the subclavian artery signal that first radio frequency sensor gathers the user;
Obtain the electrocardiosignal that EGC sensor measures the user;
Pulse wave arrival time is obtained according to the subclavian artery signal and the electrocardiosignal;
It regard the pulse wave arrival time as the pulse wave translation time.
6. method according to claim 5, it is characterised in that pulse transit is obtained according to the signal and predetermined manner Time includes:
Obtain the cardiechema signals that heart sound transducer measures the user;
According to the cardiechema signals, the electrocardiosignal and the subclavian artery signal acquisition pre-ejection time;
The pulse wave translation time is obtained according to the pulse wave arrival time and the pre-ejection time.
7. a kind of continuous blood pressure detection device of non-invasive, it is characterised in that including:
First radio frequency sensor, the signal of the superficial artery for detecting user first position;
Second radio frequency sensor, the signal of the superficial artery for detecting the user second place, the second place and described the One position is different;
Inflatable cuff with pressure sensor, the blood pressure for measuring the user;
Main control unit, respectively with first radio frequency sensor, second radio frequency sensor and it is described carry pressure sensor Inflatable cuff be connected, for according to first radio frequency sensor and second radio frequency sensor measurement signal with And predetermined manner obtains pulse wave translation time, and blood pressure and the pulse wave translation time according to the user is to described pre- If mode is calibrated, and utilizes the blood of the predetermined manner measurement user after the pulse wave translation time and calibration Pressure value.
8. equipment according to claim 7, it is characterised in that the equipment also includes:
EGC sensor, is connected with the main control unit, the electrocardiosignal for measuring the user.
9. equipment according to claim 8, it is characterised in that the equipment also includes:
Heart sound transducer, is connected with the main control unit, the cardiechema signals for measuring the user.
10. a kind of continuous blood pressure detection means of non-invasive, it is characterised in that including:
First acquisition unit, the signal for obtaining the first radio frequency sensor and the second radio frequency sensor, wherein, described first penetrates The position of video sensor and second radio frequency sensor superficial artery that to be separately positioned on user two different;
Second acquisition unit, for according to the signal acquisition pulse wave translation time, wherein, the pulse wave translation time is used In the pressure value that the user is obtained according to predetermined manner;
First control unit, user's blood pressure of the inflatable cuff measurement is obtained for controlling inflatable cuff pressurization;
First alignment unit, for carrying out school to the predetermined manner according to user's blood pressure and the pulse wave translation time It is accurate;
First measuring unit, for measuring the user using the predetermined manner after the pulse wave translation time and calibration Pressure value.
11. device according to claim 10, it is characterised in that described device also includes:
Second control unit, for the predetermined manner measurement use after using the pulse wave translation time and calibration After the continuous blood pressure at family, when the time interval for carrying out the calibration meets predetermined interval, or, in the arteries and veins measured When ripple conduction time of fighting occurs abnormal, then inflatable cuff described in secondary control pressurizes to obtain the use of the inflatable cuff measurement Family blood pressure, obtains the current blood pressure of user;
Second alignment unit, for utilizing current blood pressure and current pulse the ripple conduction time to the default side after calibration Formula is calibrated again, and predetermined manner is calibrated again;
Second measuring unit, the blood of the user is measured using the calibration predetermined manner again and current pulse ripple conduction time Pressure value.
12. device according to claim 11, it is characterised in that described device also includes:
Comparing unit, for utilizing the calibration predetermined manner again and the current pulse ripple conduction time measurement user After pressure value, the difference of the pressure value and the current pressure value of the user of relatively more described user;
Judging unit, for judging whether the difference is less than or equal to predetermined threshold value;
Delay unit, for when judging that the difference is less than or equal to the predetermined threshold value, extending the predetermined interval.
13. device according to claim 10, it is characterised in that the first acquisition unit includes:
First measurement module, the signal of the upper arm arteria brachialis for measuring the user using first radio frequency sensor;
The letter of superficial artery at second measurement module, the ankle for measuring the user using second radio frequency sensor Number.
14. device according to claim 10, it is characterised in that the second acquisition unit includes:
First acquisition module, the subclavian artery signal of the user is gathered for obtaining first radio frequency sensor;
Second acquisition module, the electrocardiosignal of the user is measured for obtaining EGC sensor;
3rd acquisition module, for obtaining pulse wave arrival time according to the subclavian artery signal and the electrocardiosignal;
Conduction time module, for regarding the pulse wave arrival time as the pulse wave translation time.
15. device according to claim 14, it is characterised in that the second acquisition unit includes:
4th acquisition module, the cardiechema signals of the user are measured for obtaining heart sound transducer;
5th acquisition module, for being penetrated according to the cardiechema signals, the electrocardiosignal and the subclavian artery signal acquisition The blood early stage time;
6th acquisition module, is passed for obtaining the pulse wave according to the pulse wave arrival time and the pre-ejection time Lead the time.
CN201710212408.9A 2017-03-31 2017-03-31 Continuous blood pressure detection method, equipment and the device of non-invasive CN107126201A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710212408.9A CN107126201A (en) 2017-03-31 2017-03-31 Continuous blood pressure detection method, equipment and the device of non-invasive

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710212408.9A CN107126201A (en) 2017-03-31 2017-03-31 Continuous blood pressure detection method, equipment and the device of non-invasive

Publications (1)

Publication Number Publication Date
CN107126201A true CN107126201A (en) 2017-09-05

Family

ID=59715894

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710212408.9A CN107126201A (en) 2017-03-31 2017-03-31 Continuous blood pressure detection method, equipment and the device of non-invasive

Country Status (1)

Country Link
CN (1) CN107126201A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107822615A (en) * 2017-11-16 2018-03-23 北京悦琦创通科技有限公司 Blood pressure measurement device and signal processing method
WO2019205175A1 (en) * 2018-04-28 2019-10-31 深圳市大耳马科技有限公司 Pulse wave conduction parameter measuring method and pulse wave conduction parameter processing device

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0048060B1 (en) * 1980-09-12 1985-01-02 Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO A device for the indirect, non-invasive and continuous measurement of blood pressure
CN1477942A (en) * 2000-10-09 2004-02-25 健资国际私人有限公司 Method and device for monitoring blood pressure
CN1849998A (en) * 2006-05-26 2006-10-25 中国人民解放军空军航空医学研究所 Method and apparatus for continuously measuring blood pressure
CN101327121A (en) * 2007-06-22 2008-12-24 香港中文大学 Physiological parameter measurement mechanism
CN104706348A (en) * 2015-03-20 2015-06-17 宁波市美灵思医疗科技有限公司 Multi-mode continuous blood pressure measurement device and self-calibration method thereof
CN105147269A (en) * 2015-06-16 2015-12-16 江苏斯坦德利医疗科技有限公司 Noninvasive continuous blood pressure measuring method
CN105748051A (en) * 2016-02-18 2016-07-13 京东方科技集团股份有限公司 Blood pressure measuring method and device
CN106037696A (en) * 2016-08-11 2016-10-26 深圳市埃微信息技术有限公司 Continuous blood pressure measurement equipment based on photoplethysmographic sensors
CN106073735A (en) * 2016-07-03 2016-11-09 深圳贝特莱电子科技股份有限公司 A kind of integrated circuit structure for continuous detecting human blood-pressure

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0048060B1 (en) * 1980-09-12 1985-01-02 Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO A device for the indirect, non-invasive and continuous measurement of blood pressure
CN1477942A (en) * 2000-10-09 2004-02-25 健资国际私人有限公司 Method and device for monitoring blood pressure
CN1849998A (en) * 2006-05-26 2006-10-25 中国人民解放军空军航空医学研究所 Method and apparatus for continuously measuring blood pressure
CN101327121A (en) * 2007-06-22 2008-12-24 香港中文大学 Physiological parameter measurement mechanism
CN104706348A (en) * 2015-03-20 2015-06-17 宁波市美灵思医疗科技有限公司 Multi-mode continuous blood pressure measurement device and self-calibration method thereof
CN105147269A (en) * 2015-06-16 2015-12-16 江苏斯坦德利医疗科技有限公司 Noninvasive continuous blood pressure measuring method
CN105748051A (en) * 2016-02-18 2016-07-13 京东方科技集团股份有限公司 Blood pressure measuring method and device
CN106073735A (en) * 2016-07-03 2016-11-09 深圳贝特莱电子科技股份有限公司 A kind of integrated circuit structure for continuous detecting human blood-pressure
CN106037696A (en) * 2016-08-11 2016-10-26 深圳市埃微信息技术有限公司 Continuous blood pressure measurement equipment based on photoplethysmographic sensors

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107822615A (en) * 2017-11-16 2018-03-23 北京悦琦创通科技有限公司 Blood pressure measurement device and signal processing method
WO2019205175A1 (en) * 2018-04-28 2019-10-31 深圳市大耳马科技有限公司 Pulse wave conduction parameter measuring method and pulse wave conduction parameter processing device

Similar Documents

Publication Publication Date Title
US20170340238A1 (en) Hydration status monitoring
US20170215754A1 (en) Methods and apparatus for enhanced fiducial point determination and non-invasive hemodynamic parameter determination
Forouzanfar et al. Oscillometric blood pressure estimation: past, present, and future
CN104873186B (en) A kind of wearable artery detection device and its data processing method
CN102811659B (en) For measuring the body worn system of continuous non-invasive blood pressure (cNIBP)
US9220903B2 (en) Optimization of pacemaker settings with R-wave detection
EP2658440B1 (en) Method for continuous non-invasive measurement of cardiac output and stroke volume of a subject
US7941213B2 (en) System and method to evaluate electrode position and spacing
US7142919B2 (en) Reconfigurable, fault tolerant multiple-electrode cardiac lead systems
Kurylyak et al. A Neural Network-based method for continuous blood pressure estimation from a PPG signal
CA2268073C (en) Non-invasive cuffless determination of blood pressure
US6865419B2 (en) Method and apparatus for measurement of mean pulmonary artery pressure from a ventricle in an ambulatory monitor
Jellema et al. Finger arterial versus intrabrachial pressure and continuous cardiac output during head-up tilt testing in healthy subjects
US5368040A (en) Apparatus and method for determining a plurality of hemodynamic variables from a single, chroniclaly implanted absolute pressure sensor
US9375160B2 (en) Systems and methods for model-based estimation of cardiac output and total peripheral resistance
Drayer et al. BP as a determinant of cardiac left ventricular muscle mass
US10052036B2 (en) Non-interfering blood pressure measuring
CN107427235A (en) Wrist wearable type Pulse transit time sensor
US6915162B2 (en) Implantable medical device for measuring ventricular pressure
US7367951B2 (en) System and method for detecting cardiovascular health conditions using hemodynamic pressure waveforms
US8613705B2 (en) Central venous pressure sensor and method to control a fluid or volume overload therapy
EP1971395B1 (en) System for interpreting hemodynamic data incorporating patient posture information
US7137955B2 (en) Methods and systems for distal recording of phonocardiographic signals
US8108034B2 (en) Systems and methods for valvular regurgitation detection
US6458086B1 (en) Implantable blood flow monitoring system

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination