CN113631725A - 用于诊断和治疗目的的对外排体相关微生物组的分离和检测 - Google Patents
用于诊断和治疗目的的对外排体相关微生物组的分离和检测 Download PDFInfo
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- CN113631725A CN113631725A CN202080024007.0A CN202080024007A CN113631725A CN 113631725 A CN113631725 A CN 113631725A CN 202080024007 A CN202080024007 A CN 202080024007A CN 113631725 A CN113631725 A CN 113631725A
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- C12Q2600/00—Oligonucleotides characterized by their use
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
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- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962802994P | 2019-02-08 | 2019-02-08 | |
| US62/802,994 | 2019-02-08 | ||
| PCT/US2020/017224 WO2020163724A1 (en) | 2019-02-08 | 2020-02-07 | Isolation and detection of exosome-associated microbiome for diagnostic and therapeutic purposes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113631725A true CN113631725A (zh) | 2021-11-09 |
Family
ID=71947984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202080024007.0A Pending CN113631725A (zh) | 2019-02-08 | 2020-02-07 | 用于诊断和治疗目的的对外排体相关微生物组的分离和检测 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220137056A1 (https=) |
| EP (1) | EP3921325A4 (https=) |
| JP (1) | JP2022519326A (https=) |
| KR (1) | KR20210125532A (https=) |
| CN (1) | CN113631725A (https=) |
| AU (1) | AU2020218358A1 (https=) |
| CA (1) | CA3129250A1 (https=) |
| WO (1) | WO2020163724A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114486829A (zh) * | 2022-01-24 | 2022-05-13 | 复旦大学 | 一种微量外泌体捕集并计数的方法 |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3775258A4 (en) | 2018-03-28 | 2022-01-26 | Board of Regents, The University of Texas System | IDENTIFICATION OF EPIGENETIC ALTERATIONS IN DNA ISOLATED FROM EXOSOMES |
| WO2021158966A1 (en) | 2020-02-05 | 2021-08-12 | Board Of Regents, The University Of Texas System | Diagnostic and prognostic utility of exosomes in immunotherapy |
| EP4373976A4 (en) * | 2021-07-20 | 2025-06-18 | Liquid Biopsy Holdco, LLC | METHODS FOR DIAGNOSIS OF DISEASE USING MICROBIAL EXTRACELLULAR VESICLE (MEV) ANALYTES |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1308685A (zh) * | 1998-04-01 | 2001-08-15 | 简珀恩特联合股份有限公司 | 核酸检测方法 |
| CN104024430A (zh) * | 2011-08-26 | 2014-09-03 | 微生物诊断有限责任公司 | 用于诊断和治疗心脏缺陷的方法 |
| US20150176073A1 (en) * | 2012-07-18 | 2015-06-25 | Exosome Diagnostics, Inc. | Use of microvesicles in diagnosis, prognosis, and treatment of medical diseases and conditions |
| US20170059572A1 (en) * | 2013-12-04 | 2017-03-02 | Board Of Regents, The University Of Texas System | Analysis of genomic dna, rna, and proteins in exosomes for diagnosis and theranosis |
| WO2018175422A1 (en) * | 2017-03-23 | 2018-09-27 | Quadrant Biosciences Inc. | Method for diagnosing or monitoring conditions characterized by abnormal temporal variations method of normalizing epigenetic data to compensate for temporal variations |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101810799B1 (ko) * | 2008-02-01 | 2017-12-19 | 더 제너럴 하스피탈 코포레이션 | 의학적 질환 및 병태의 진단, 예후, 및 치료에 있어서 미세소포체의 용도 |
| WO2010056337A2 (en) * | 2008-11-12 | 2010-05-20 | Caris Mpi, Inc. | Methods and systems of using exosomes for determining phenotypes |
| WO2011027956A2 (ko) * | 2009-09-04 | 2011-03-10 | 주식회사이언메딕스 | 그람 양성 박테리아에서 유래한 세포밖 소포체 및 이를 이용한 질병 모델 |
| US20130029339A1 (en) * | 2009-09-09 | 2013-01-31 | The General Hospital Corporation | Use of microvesicles in analyzing kras mutations |
| KR101798176B1 (ko) * | 2014-12-16 | 2017-11-15 | 주식회사 엠디헬스케어 | 세균 유래의 나노소포체를 이용한 세균성 감염질환 원인균 동정방법 |
| KR101726488B1 (ko) * | 2015-02-23 | 2017-04-13 | 이화여자대학교 산학협력단 | 바실러스 속 세균 유래 세포밖 소포체를 포함하는 임신관련 질환 치료용 조성물 |
| US10526665B2 (en) * | 2016-03-04 | 2020-01-07 | University Of Notre Dame Du Lac | Exosomal biomarkers diagnostic of tuberculosis |
| JP2018063182A (ja) * | 2016-10-13 | 2018-04-19 | 国立大学法人 新潟大学 | 腸内細菌の菌叢分析方法及び被検体におけるヘリコバクター・ピロリに対するアレルギーの検出方法 |
| KR20180076308A (ko) * | 2016-12-26 | 2018-07-05 | 주식회사 엠디헬스케어 | 세균 메타게놈 분석을 통한 췌장암 진단방법 |
| WO2018124618A1 (ko) * | 2016-12-26 | 2018-07-05 | 주식회사 엠디헬스케어 | 세균 메타게놈 분석을 통한 췌장암 진단방법 |
| KR101940426B1 (ko) * | 2016-12-28 | 2019-01-18 | 주식회사 엠디헬스케어 | 세균 메타게놈 분석을 통한 대장종양 진단 방법 |
| WO2018124735A1 (ko) * | 2016-12-28 | 2018-07-05 | 주식회사 엠디헬스케어 | 세균 메타게놈 분석을 통한 대장종양 진단 방법 |
-
2020
- 2020-02-07 EP EP20752533.8A patent/EP3921325A4/en active Pending
- 2020-02-07 AU AU2020218358A patent/AU2020218358A1/en not_active Abandoned
- 2020-02-07 JP JP2021546281A patent/JP2022519326A/ja active Pending
- 2020-02-07 CA CA3129250A patent/CA3129250A1/en active Pending
- 2020-02-07 US US17/429,281 patent/US20220137056A1/en active Pending
- 2020-02-07 WO PCT/US2020/017224 patent/WO2020163724A1/en not_active Ceased
- 2020-02-07 KR KR1020217028785A patent/KR20210125532A/ko not_active Ceased
- 2020-02-07 CN CN202080024007.0A patent/CN113631725A/zh active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1308685A (zh) * | 1998-04-01 | 2001-08-15 | 简珀恩特联合股份有限公司 | 核酸检测方法 |
| CN104024430A (zh) * | 2011-08-26 | 2014-09-03 | 微生物诊断有限责任公司 | 用于诊断和治疗心脏缺陷的方法 |
| US20150176073A1 (en) * | 2012-07-18 | 2015-06-25 | Exosome Diagnostics, Inc. | Use of microvesicles in diagnosis, prognosis, and treatment of medical diseases and conditions |
| US20170059572A1 (en) * | 2013-12-04 | 2017-03-02 | Board Of Regents, The University Of Texas System | Analysis of genomic dna, rna, and proteins in exosomes for diagnosis and theranosis |
| WO2018175422A1 (en) * | 2017-03-23 | 2018-09-27 | Quadrant Biosciences Inc. | Method for diagnosing or monitoring conditions characterized by abnormal temporal variations method of normalizing epigenetic data to compensate for temporal variations |
Non-Patent Citations (3)
| Title |
|---|
| DAVID C. EMERY等: "16S rRNA Next Generation Sequencing Analysis Shows Bacteria in Alzheimer’s Post-Mortem Brain", 《FRONTIERS IN AGING NEUROSCIENCE》, vol. 9, 20 June 2017 (2017-06-20), pages 1 - 13, XP055592746, DOI: 10.3389/fnagi.2017.00195 * |
| JIN-YOUNG PARK等: "Metagenome Analysis of Bodily Microbiota in a Mouse Model of Alzheimer Disease Using Bacteria-derived Membrane Vesicles in Blood", 《EXP NEUROBIOL》, vol. 26, no. 6, 31 December 2017 (2017-12-31), pages 369 - 379, XP055547921, DOI: 10.5607/en.2017.26.6.369 * |
| JIN-YOUNG PARK等: "Metagenome Analysis of Bodily Microbiota in a Mouse Model of Alzheimer Disease Using Bacteria-derived Membrane Vesicles in Blood", 《EXPERIMENTAL NEUROBIOLOGY》, vol. 26, no. 6, 31 December 2017 (2017-12-31), pages 369 - 379, XP055547921, DOI: 10.5607/en.2017.26.6.369 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114486829A (zh) * | 2022-01-24 | 2022-05-13 | 复旦大学 | 一种微量外泌体捕集并计数的方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3921325A4 (en) | 2022-11-23 |
| JP2022519326A (ja) | 2022-03-22 |
| EP3921325A1 (en) | 2021-12-15 |
| KR20210125532A (ko) | 2021-10-18 |
| AU2020218358A1 (en) | 2021-08-26 |
| US20220137056A1 (en) | 2022-05-05 |
| WO2020163724A1 (en) | 2020-08-13 |
| CA3129250A1 (en) | 2020-08-13 |
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