CN113631575A - 抗bcma嵌合抗原受体 - Google Patents

抗bcma嵌合抗原受体 Download PDF

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Publication number
CN113631575A
CN113631575A CN202080020956.1A CN202080020956A CN113631575A CN 113631575 A CN113631575 A CN 113631575A CN 202080020956 A CN202080020956 A CN 202080020956A CN 113631575 A CN113631575 A CN 113631575A
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car
cell
seq
comprises seq
cells
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Chinese (zh)
Inventor
张毅
C·A·斯图尔特
M·库尔特奥卢
M·V·卡拉约格鲁
M·S·辛格
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Cartesian Therapeutics Inc
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Cartesian Therapeutics Inc
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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CN202080020956.1A 2019-03-15 2020-03-13 抗bcma嵌合抗原受体 Pending CN113631575A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962819068P 2019-03-15 2019-03-15
US62/819,068 2019-03-15
PCT/US2020/022671 WO2020190737A1 (en) 2019-03-15 2020-03-13 Anti-bcma chimeric antigen receptors

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CN113631575A true CN113631575A (zh) 2021-11-09

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CN202080020956.1A Pending CN113631575A (zh) 2019-03-15 2020-03-13 抗bcma嵌合抗原受体

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US (4) US10934337B2 (https=)
EP (1) EP3938401A4 (https=)
JP (1) JP7379654B2 (https=)
KR (3) KR102588292B1 (https=)
CN (1) CN113631575A (https=)
AU (1) AU2020241428B2 (https=)
CA (2) CA3199205A1 (https=)
IL (1) IL285909B2 (https=)
MX (1) MX2021011196A (https=)
WO (1) WO2020190737A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023193660A1 (zh) * 2022-04-03 2023-10-12 上海先博生物科技有限公司 增强型嵌合抗原受体及其应用

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CA3120563A1 (en) 2018-11-26 2020-06-04 Nkarta, Inc. Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
EP3773918A4 (en) 2019-03-05 2022-01-05 Nkarta, Inc. CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY
CA3199205A1 (en) 2019-03-15 2020-09-24 Cartesian Therapeutics, Inc. Anti-bcma chimeric antigen receptors
WO2022220648A1 (ko) * 2021-04-15 2022-10-20 주식회사 유틸렉스 Hla-dr 특이적 키메라 항원 수용체 및 이의 용도
WO2023150698A2 (en) * 2022-02-04 2023-08-10 Nkilt Therapeutics, Inc. Chimeric ilt receptor compositions and methods
AU2024279278A1 (en) 2023-05-31 2025-12-18 Capstan Therapeutics, Inc. Lipid nanoparticle formulations and compositions
US20250127728A1 (en) 2023-10-05 2025-04-24 Capstan Therapeutics, Inc. Constrained Ionizable Cationic Lipids and Lipid Nanoparticles
WO2025076113A1 (en) 2023-10-05 2025-04-10 Capstan Therapeutics, Inc. Ionizable cationic lipids with conserved spacing and lipid nanoparticles
WO2025158437A1 (en) * 2024-01-24 2025-07-31 Sheba Impact Ltd. T-cell specific rna constructs
WO2025217452A1 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Constrained ionizable cationic lipids and lipid nanoparticles
WO2025217454A2 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Ionizable cationic lipids and lipid nanoparticles

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US20160046724A1 (en) * 2014-07-21 2016-02-18 The Trustees Of The University Of Pennsylvania Treatment of cancer using humanized anti-bcma chimeric antigen receptor
CN106795217A (zh) * 2014-07-24 2017-05-31 蓝鸟生物公司 Bcma嵌合抗原受体
WO2018140725A1 (en) * 2017-01-26 2018-08-02 Novartis Ag Cd28 compositions and methods for chimeric antigen receptor therapy
CN109265550A (zh) * 2018-09-25 2019-01-25 华东师范大学 Bcma抗体、嵌合抗原受体和药物
CN109293772A (zh) * 2018-09-25 2019-02-01 上海邦耀生物科技有限公司 靶向bcma蛋白的抗体、嵌合抗原受体和药物

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