CN113599423A - 一种治疗贫血的中药组合物 - Google Patents
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Abstract
本发明公开了一种治疗贫血(再生障碍性贫血、失血性贫血、溶血性贫血等)的中药组合物,是由下列重量份的原料药组成:川芎、一叶萩、牛马藤、鱼鳔、牛西西、小红参。
Description
技术领域
本发明属于中药技术领域,尤其是涉及一种治疗贫血的中药组合物。
背景技术
贫血是指单位容积血液内的血红蛋白低于正常及红细胞数目减少。贫血症是由于身体无法制造足够的血红蛋白(一种将氧气输送到血红细胞和身体各个组织的蛋白质)造成的。许多原因都可以造成贫血,所以根据病因的不同将贫血分为缺铁性贫血、再生障碍性贫血、失血性贫血、溶血性贫血等等。过去贫血的主要原因是营养不良,近年来因减肥而造成营养失调,形成了严重贫血的又一人群。几乎有20%的女性有患贫血症的危险。世界卫生组织统计:全球约有30亿人不同程度贫血,每年因患贫血引致各类疾病而死亡的人数上千万。目前,没有治疗再生障碍性贫血、溶血性贫血、慢性失血性贫血的特效药。
发明内容
本发明的目的在于改进已有技术的不足而提供一种治疗贫血的中药组合物,可以有效地改善甚至消除患者的临床症状,具有治疗效果显著、治疗周期短、无毒副作用等特点。
贫血属于中医学“血虚”、“萎黄”、“虚劳”以及“血证”范畴,气血的生成,一是靠营养物质的摄入,二是靠脾胃的运化功能。脾为后天之本,气血生化之源。健脾则利于血虚的改善。如果脾虚,则不能化生气血,此乃导致气血两虚的重要原因。
气能生血,血的组成与生成过程离不开气和气化功能;气能行血,血的运行要依赖气的推动,气虚则会导致血行迟缓、血行不利、甚至血瘀;气能摄血,气如果气虚不能固摄,就会导致许多出血病,这也是导致贫血的主要原因。申请人认为治疗贫血应补气健脾,气血同补。基于上述理论,本发明提供了一种治疗贫血的中药组合物,由下列重量份的原料药组成:人参、川芎4.5~9重量份;一叶萩6~12重量份;牛马藤、鱼鳔、牛西西、小红参15~30重量份。
在一个优选的实施方案中,所述治疗贫血的中药组合物由下列重量份的原料药组成:人参、川芎9重量份;一叶萩12重量份;牛马藤、鱼鳔、牛西西、小红参30重量份。
其中,牛西西:苦、酸,寒。凉血止血,清热解毒,杀虫。对再生障碍性贫血之出血等有效率在90%以上。能使血小板减少症患者的血小板数目显着上升;并对各种出血症有良好的止血效果。
牛马藤:味苦;微苦;性温。归肝;胃经。活血调经;补血舒筋。治再生障碍性贫血。
小红参:甘;微苦,温。归肝经。活血舒筋;祛瘀生新;调养气血。用于肺痨咳血;贫血等。
一叶萩:味辛;苦;性微温;小毒归肝;肾;脾经。一叶萩对脊髓具明显的兴奋作用,对骨髓多能干细胞及粒糸前体细胞均有明显促进作用。
鱼鳔:味甘;性平。归肾;肝经。补肝肾;养血止血;散瘀消肿。用于再生障碍性贫血等
川芎:味辛,温。归肝、胆、心包经。活血行气,祛风止痛。
川芎能促进骨髓造血细胞的恢复、改善骨髓微环境、促进骨髓造血重建。促进骨髓细胞的增殖分化,从而保证有充足的骨髓细胞发育成熟,进入血液循环。
本发明是由中国传统的中草药制成,根据中医辨证论治及现代医学的若干原则,以某些成分确定、功效明晰的天然提取物的有序配伍,组合成了有效治疗贫血的中药。
本发明可以贯穿于贫血治疗的全过程,用本药方施治,每日一剂,水煎100-150ml,分成两份,早晚各一份服用,治疗贫血效果显著,标本兼治,见效快,治愈率高,不易复发,安全可靠,无明显毒副反应,便于患者长期坚持服用,用药多年来,患者无任何不良反应,跟踪血液检查正常。
本发明的中药组合物原料易得,工艺简单,成本低,效率高,有利于制药企业进行药品生产、质量控制;产品价格低,易于被患者接受。
本发明还提供了一种由上述治疗贫血的中药组合物制成的口服制剂,所述口服制剂包括口服液、片剂、胶囊剂、丸剂等,优选剂型为片剂和胶囊剂,一日一剂,分早晚两次服用。
本发明的中药组合物可以制备成多种剂型。例如,将煎煮后的药液杀菌消毒后装袋,制成口服液;或者将煎煮后的药液进行浓缩,烘干后,加入医学上可接收的辅料,然后制成片剂、胶囊剂、丸剂等。
所述医学上可接收的辅料包括淀粉、糊精、羧甲基纤维素钠、聚乙二醇、磷酸氢钙、海藻酸钠、山梨酸钾等。
以上所述,仅是本发明的较佳实施例而已,并非对本发明作任何形式上的限制,本领域技术人员利用上述揭示的技术内容做出些许简单修改、等同变化或修饰,均落在本发明的保护范围内。
Claims (4)
1.一种治疗贫血(再生障碍性贫血、失血性贫血、溶血性贫血等,下同)的中药组合物,其特征是由下列重量份的原料药组成:川芎4.5~9重量份;一叶萩6~12重量份;牛马藤、鱼鳔、牛西西、小红参15~30重量份。
2.根据权利要求1所述的一种治疗贫血的中药组合物,其特征是由下列重量份的原料药组成:川芎9重量份;一叶萩12重量份;牛马藤、鱼鳔、牛西西、小红参30重量份。
3.一种治疗贫血的口服制剂,其特征是由权利要求1或2中任一项所述的中药组合物制成。
4.根据权利要求3所述的一种治疗贫血的口服制剂,其特征是包括口服液、片剂、胶囊剂、丸剂,优选口服液和片剂。
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