CN1135978C - 性润舒膏 - Google Patents
性润舒膏 Download PDFInfo
- Publication number
- CN1135978C CN1135978C CNB991230922A CN99123092A CN1135978C CN 1135978 C CN1135978 C CN 1135978C CN B991230922 A CNB991230922 A CN B991230922A CN 99123092 A CN99123092 A CN 99123092A CN 1135978 C CN1135978 C CN 1135978C
- Authority
- CN
- China
- Prior art keywords
- vitamin
- metronidazole
- accounts
- vaseline
- relaxing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000002674 ointment Substances 0.000 title 1
- 230000002040 relaxant effect Effects 0.000 title 1
- 230000036299 sexual function Effects 0.000 title 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 18
- VAOCPAMSLUNLGC-UHFFFAOYSA-N metronidazole Chemical compound CC1=NC=C([N+]([O-])=O)N1CCO VAOCPAMSLUNLGC-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229960000282 metronidazole Drugs 0.000 claims abstract description 10
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims abstract description 9
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims abstract description 9
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 9
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims abstract description 9
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 9
- 229940057995 liquid paraffin Drugs 0.000 claims abstract description 9
- 229940099259 vaseline Drugs 0.000 claims abstract description 9
- 235000019155 vitamin A Nutrition 0.000 claims abstract description 9
- 239000011719 vitamin A Substances 0.000 claims abstract description 9
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 9
- 229940046009 vitamin E Drugs 0.000 claims abstract description 9
- 239000011709 vitamin E Substances 0.000 claims abstract description 9
- 229940045997 vitamin a Drugs 0.000 claims abstract description 9
- 239000000203 mixture Substances 0.000 claims abstract description 8
- MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 claims description 14
- 229960003405 ciprofloxacin Drugs 0.000 claims description 7
- 230000027326 copulation Effects 0.000 claims description 6
- 239000006071 cream Substances 0.000 claims description 6
- 230000001050 lubricating effect Effects 0.000 claims description 6
- 230000001568 sexual effect Effects 0.000 abstract description 12
- 229940088597 hormone Drugs 0.000 abstract description 2
- 239000005556 hormone Substances 0.000 abstract description 2
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical compound C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 abstract 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 9
- 230000000694 effects Effects 0.000 description 9
- 230000001954 sterilising effect Effects 0.000 description 5
- 238000004659 sterilization and disinfection Methods 0.000 description 5
- 208000019802 Sexually transmitted disease Diseases 0.000 description 4
- 210000002919 epithelial cell Anatomy 0.000 description 4
- 239000003974 emollient agent Substances 0.000 description 3
- 238000005461 lubrication Methods 0.000 description 3
- 206010036596 premature ejaculation Diseases 0.000 description 3
- 210000001215 vagina Anatomy 0.000 description 3
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 2
- 241000588653 Neisseria Species 0.000 description 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 description 2
- 239000000645 desinfectant Substances 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000012467 final product Substances 0.000 description 2
- 230000002147 killing effect Effects 0.000 description 2
- 210000004877 mucosa Anatomy 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 229920000136 polysorbate Polymers 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 2
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 208000004483 Dyspareunia Diseases 0.000 description 1
- 235000019687 Lamb Nutrition 0.000 description 1
- 206010024419 Libido decreased Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 206010046914 Vaginal infection Diseases 0.000 description 1
- 201000008100 Vaginitis Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 206010047791 Vulvovaginal dryness Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000003756 cervix mucus Anatomy 0.000 description 1
- 229940087211 ciprofloxacin and metronidazole Drugs 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 210000001672 ovary Anatomy 0.000 description 1
- 210000003899 penis Anatomy 0.000 description 1
- 230000000505 pernicious effect Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 210000000664 rectum Anatomy 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
本发明涉及可以房事使用,快速增加阴道润滑性,提高性爱快感,而无激素,无刺激性,使用方便的组合物。该组合物:凡士林占组合物重量比为55%-70%,液体石蜡为25%-40%,维生素A为1%-3%,维生素E为1%-3%,灭滴灵为1%-4%,喹诺酮类药为1%-4%。
Description
本发明涉及房事润滑剂型的性润舒膏。
中国专利公告号(1077373)公开了这样一种《房事润滑剂型卫生消杀药》,该药包括羧甲基纤维素钠、吐温、甘油、洗必泰、灭滴灵,具有润滑阴道、消毒和灭菌作用,可达到预防妇女病和性病的目的,但由于甘油具有吸湿性能,对阴道上皮细胞有一定的刺激脱水作用,另外,溶液剂型使用时易溢出阴道口外,使用较不方便。
因此本发明的目的在于提供无激素、无刺激性,配制和使用都方便的性润舒膏。
为达到上述目的,本发明由能提高阴道润滑性的凡士林、液体石蜡;具有滋养粘膜上皮细胞兼有润滑作用的维生素E、维生素A和消炎作用的灭滴灵、喹诺酮类药,具体讲喹诺酮类药是环丙沙星组合而成。
按照本发明,所述组合物含55%-70%(重量)的凡士林和25%-40%(重量)的液体石蜡,含1%-3%(重量)的维生素A和1%-3%(重量)的维生素E,含1%-4%(重量)的环丙沙星和1%-4%(重量)的灭滴灵。
当凡士林占组合物的重量比为60%-65%,液体石蜡为30%-40%,维生素A为1%-2%,维生素E为1%-2%,环丙沙星为1.5%-3%,灭滴灵为1.5%-3%时,其效果更佳。
由于本发明采用了凡士林、液体石蜡作为组合物的组分,起到了润滑和形成脂质膜,对阴道起到保护作用,预防产生磨擦损伤,提高性交快感;而维生素A、维生素E使粘膜、皮肤上皮细胞滋养,延缓了细胞的老化、脱落;环丙沙星起到杀灭革兰氏阳性、阴性细菌如淋球菌等的作用;灭滴灵对滴虫、厌氧菌等具有杀灭作用,同时也可治疗男子早泄。由于润滑性好,有延长性交接触时间之效果。临床证明,经609例性冷淡、阴道分泌物减少、阴道干涩、性交疼痛的妇女应用,其中年龄因素即中老年人的365例;体质因素如情绪变化、体质虚弱、慢性疾病等166例;手术因素如卵巢、子宫及女性直肠良、恶性癌病手术者77例;其他男子早泄者8例。随访作用最长时间15年,最短一个月,效果满意,有效率达百分之百,未见不良副作用。
在以下实施例中将进一步举例说明本发明,这些实施例仅用于说明本发明而对本发明没有限制。
类别 | 构成 | 效果 | 适用范围 |
房事润滑剂型卫生消杀药 | 羧甲基纤维素钠、吐温、甘油、洗必泰、灭滴灵 | 润滑阴道、消毒和灭菌,可预防妇女病和性病 | 适用于各年龄段妇女使用 |
例I | A∶B∶C∶D | 1、增加阴道润滑性,提高性交快感。2、滋养粘膜皮肤、上皮细胞,提高男女性器官抵抗微生物、细菌、病毒的侵袭。3、保护男女性器官、皮肤、粘膜,避免性交磨擦损伤,防治性生活不舒适或疼痛。4、消炎作用,防治淋菌,厌氧菌、滴虫等性接触感染。5、延长性交接触时间,防治男子早泄。 | 各年龄段均适宜使用,尤其适宜性欲旺盛的年轻人或有阴道炎者。 |
例II | A∶B∶C | 上述效果1+2+3+5 | 适用于各年龄段妇女使用,尤其是中老年妇女 |
例III | A∶B | 上述效果的1+3+5 |
注:A、凡士林 B、液体石蜡 C、维生素A、维生素E D、环丙沙星、灭滴灵
产业制造时,首先将凡士林和液体石蜡经高压消毒混合作为基质,然后将环丙沙星和灭滴灵研成细粉,再经过120目筛精选,加入由维生素A和维生素E药液搅拌均匀后,加入基质中用软羔板搅拌均匀即可。
使用方法为:性交前将该组合物1-1.5mg,涂抹在阴道口上或头阴茎上即可。
Claims (3)
1、一种性润舒膏,其组成如下:凡士林占组合物重量比为55%-70%,液体石蜡为25%-40%,维生素A为1%-3%,维生素E为1%-3%,灭滴灵为1%-4%,喹诺酮类药为1%-4%。
2、根据权利要求1所述的性润舒膏,其中喹诺酮类药是环丙沙星。
3、根据权利要求1所述的性润舒膏,其中凡士林占组合物重量比为60%-65%,液体石蜡占重量比为30%-40%,维生素A占重量比为1%-2%,维生素E占重量比为1%-2%,环丙沙星占重量比为1.5%-3%,灭滴灵占重量比为1.5%-3%。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB991230922A CN1135978C (zh) | 1999-12-08 | 1999-12-08 | 性润舒膏 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB991230922A CN1135978C (zh) | 1999-12-08 | 1999-12-08 | 性润舒膏 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1298703A CN1298703A (zh) | 2001-06-13 |
CN1135978C true CN1135978C (zh) | 2004-01-28 |
Family
ID=5282794
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB991230922A Expired - Fee Related CN1135978C (zh) | 1999-12-08 | 1999-12-08 | 性润舒膏 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN1135978C (zh) |
-
1999
- 1999-12-08 CN CNB991230922A patent/CN1135978C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1298703A (zh) | 2001-06-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6328991B1 (en) | Composition and method for prevention of sexually transmitted diseases, including aids | |
EP1263411B1 (en) | Compositions and use thereof for trapping and inactivating pathogenic microbes and spermatozoa | |
Amaral et al. | Study of the vaginal tolerance to Acidform, an acid-buffering, bioadhesive gel | |
Hellberg et al. | Self-treatment of female external genital warts with 0.5% Podophyllotoxin cream (Condyline®) vs weekly applications of 20% Podophyllin Solution | |
AU2001243431A1 (en) | Compositions and methods for trapping and inactivating pathogenic microbes and spermatozoa | |
US20030211173A1 (en) | Lubrication composition | |
CN102895256B (zh) | 一种适用于女性屏障杀精双重避孕作用的壳聚糖复合凝胶泡沫剂及其制备方法 | |
US11806325B2 (en) | Topical fertility promoting product and manufacturing method | |
US20020151521A1 (en) | Universal antiviral composition | |
US20050037033A1 (en) | Microbicidal compositions and methods and use | |
Ballagh et al. | Safety of single daily use for one week of C31G HEC gel in women | |
US20120270936A1 (en) | Composition and method for treatment of inflamation and infections of the genitalia, contraceptive and the prophylaxis of sexually transmitted diseases | |
Powell | Vaginal thrush: quality of life and treatments | |
CN1135978C (zh) | 性润舒膏 | |
WO2000015192A1 (en) | Methods and materials related to bioadhesive contraceptive gels | |
EP1646378B1 (en) | Pharmaceutical compositions comprising ascorbic acid for the treatment of fungal superfinfections and fungal recurrences | |
US20060264857A1 (en) | Absorbent articles with buffer | |
US7687078B1 (en) | Method of treatment | |
Baptista et al. | Contact dermatitis from sodium fusidate. | |
WO1999003463A1 (en) | Genital lubricants with zinc to reduce irritation and allergic reactions | |
CN101249084B (zh) | 可预防性传播疾病的消毒组方 | |
RU2173142C1 (ru) | Вагинальный контрацептив | |
WO2009088125A1 (en) | A composition for sanitary supplies comprising mucosal immunoadjuvant and a preparation method thereof | |
CN104189657B (zh) | 兼具防治下生殖道感染的外用避孕药 | |
DE COSTA | Infections of the vagina and vulva |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C19 | Lapse of patent right due to non-payment of the annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |