CN113583973A - High-lytic Klebsiella pneumoniae RDP-KP-20007 and application thereof - Google Patents

Abstract

The invention discloses a high-lytic Klebsiella pneumoniae RKP-KP-20007 and application thereof, wherein a host is Klebsiella pneumoniae, the head of the phage is icosahedron and is stereoscopically symmetrical through electron microscope observation, the head of the phage is 72.640nm, the tail of the phage is 177.797nm, the phage is of the order of tailed phage, and the preservation number is CGMCC No. 22495. The Klebsiella pneumoniae RKP-KP-20007 has strong lytic effect on Klebsiella pneumoniae in poultry breeding environment, can efficiently treat Klebsiella pneumoniae diseases caused by pathogenic bacteria in poultry breeding, can be used as a disinfectant, and provides a phage source for industrialized, large-scale and programmed production of phages and treatment of poultry breeding bacterial diseases caused by Klebsiella pneumoniae.

Description

High-lytic Klebsiella pneumoniae RDP-KP-20007 and application thereof

Technical Field

The invention relates to the technical field of biology, in particular to a high-lytic Klebsiella pneumoniae and application thereof in Klebsiella pneumoniae infection in poultry breeding.

Background

Klebsiella pneumoniae, belonging to the genus Klebsiella of the family Enterobacteriaceae, is a common gram-negative bacterium, widely exists in various environments in nature, and is a very common food-borne pathogenic bacterium. Klebsiella pneumoniae mainly infects humans and animals, can cause high mortality, and causes significant economic loss to the breeding industry worldwide. Animal products contaminated with klebsiella pneumoniae (e.g., meat, egg, milk, etc.) transmit pathogens to humans through the food chain, thereby creating a health hazard to humans and animals. The traditional Chinese medicine composition can generate septicemia, pneumonia and urinary tract infection, can cause death of people and poultry in severe cases, is one of important conditioned pathogens and pathogens, and seriously harms public health.

The bacteriophage is a virus taking bacteria as a host, has no cell structure, must be copied and propagated depending on the host, is widely existed in the natural world, has strong specificity and self-lysis capability, has the functions of lysing the bacteria and controlling the growth of the bacteria, can adjust the growth and the decay of the bacteria in the natural world, takes the Klebsiella pneumoniae bacteriophage as a biological bactericide to prevent, treat and control the Klebsiella pneumoniae bacteriosis in the poultry breeding process, has the advantages of low pollution and high efficiency, and reduces the influence of artificial activities on the natural world to a certain extent. Therefore, the natural enemy phage of the bacteria is utilized to solve the biological control approach with wide prospect for the bacteria.

The invention provides a safe and reliable lytic Klebsiella pneumoniae phage for treating avian Klebsiella pneumoniae, expands a phage stock library and lays a foundation for developing antibiotic substitutes for treating Klebsiella pneumoniae, aiming at the order of comprehensive banning of corresponding countries and solving the problems of bacterial drug resistance and antibiotic abuse.

Disclosure of Invention

The invention aims to provide a high-lytic Klebsiella pneumoniae RDP-KP-20007 to replace antibiotics in the prevention and treatment of poultry breeding, and solve the problems of untimely treatment due to acute morbidity of poultry animals, ineffective medication due to drug resistance of pathogenic bacteria and the like.

In order to achieve the purpose, the invention adopts the following technical scheme:

a high-lytic Klebsiella pneumoniae RKP-KP-20007 has a icosahedron head, is three-dimensionally symmetrical, has a head length of 72.640nm and a tail length of 177.797nm, is a long-tailed phage of the order of tailed phage, and has no virulence genes and lysogenic genes. The phage is preserved in China general microbiological culture Collection center (CGMCC) at 6 months and 3 days in 2021, and the preservation addresses are as follows: no. 3 of Xilu No. 1 of Beijing, Chaoyang, and the preservation number is CGMCC No. 22495.

Preferably, the Klebsiella pneumoniae (Klebsiella pneumoniae phase) RDP-KP-20007 has an optimum temperature of 37 ℃ and a potency of 10^11 pfu/mL.

Preferably, the Klebsiella pneumoniae phage (Klebsiella pneumoniae phase) RDP-KP-20007 has strong lysis effect on Klebsiella pneumoniae in poultry breeding environment.

The second purpose of the invention is to provide the application of Klebsiella pneumoniae RDP-KP-20007 in preparing medicines for preventing and/or treating diseases caused by Klebsiella pneumoniae.

The third purpose of the invention is to provide the application of Klebsiella pneumoniae RDP-KP-20007 in preparing feed for preventing and/or treating diseases caused by Klebsiella pneumoniae.

The fourth purpose of the invention is to provide a sterilization composition for preventing and treating Klebsiella pneumoniae, which comprises an effective amount of Klebsiella pneumoniae (Klebsiella pneumoniae phase) RDP-KP-20007.

The fifth purpose of the invention is to provide the application of the Klebsiella pneumoniae phage, which is realized by using the Klebsiella pneumoniae phase RDP-KP-20007 as a potential therapeutic drug or health product for bacterial infection caused by Klebsiella pneumoniae.

The sixth purpose of the invention is to provide an additive for preventing and/or treating diseases caused by Klebsiella pneumoniae, the effective component of which comprises Klebsiella pneumoniae (Klebsiella pneumoniae phase) RDP-KP-20007 of the invention.

The seventh purpose of the invention is to provide a cleaning agent or disinfectant for poultry breeding environment, which comprises the Klebsiella pneumoniae phase RDP-KP-20007.

The invention has the beneficial effects that:

(1) the invention discovers and separates a pathogenic Klebsiella pneumoniae BK-20007, and separates a Klebsiella pneumoniae phage RDP-KP-20007 by taking the pathogenic Klebsiella pneumoniae BK-20007 as a host, wherein the phage RDP-KP-20007 has strong cracking effect on the pathogenic Klebsiella pneumoniae BK-20007 in a poultry breeding environment, and provides a phage source for the industrial production of phage for preventing and treating the pathogenic Klebsiella pneumoniae BK-20007 in the poultry breeding environment;

(2) the Klebsiella pneumoniae RDP-KP-20007 provided by the invention is a virulent phage test phage separated from nature and does not contain virulence genes or undesirable genes; the invention does not carry out any genetic modification on the test phage;

(3) the Klebsiella pneumoniae RDP-KP-20007 provided by the invention has an obvious lysis effect within 4 hours after the Klebsiella pneumoniae RDP-KP-20007 is added into the environment, has stronger lysis activity and shows good application prospect.

(4) The Klebsiella pneumoniae phage RDP-KP-20007 provided by the invention has good application prospect in prevention and control of pathogenic Klebsiella pneumoniae of poultry animals.

(5) The Klebsiella pneumoniae RDP-KP-20007 provided by the invention can be used as an effective component of various products applied to environmental disinfection.

(7) The Klebsiella pneumoniae RDP-KP-20007 can be used as an effective component of various products applied to environmental disinfection, such as water distribution systems, medical facilities, aquaculture facilities, public and private facilities or other environmental surfaces in the forms of liquid soaking, spraying, combined use with an aqueous carrier and the like for disinfection and decontamination, and can effectively control the growth and activity of target bacteria. The liquid soaking, spraying forms include but are not limited to detergents, disinfectants, detergents, etc.; the aqueous carrier includes but is not limited to phosphate buffer, LB medium, chloride free water, etc.

(6) The Klebsiella pneumoniae phage RDP-KP-20007 can effectively kill Klebsiella pneumoniae on the surface of the environment and prevent and treat the pollution of the Klebsiella pneumoniae during the preservation process of poultry, and can be used as an effective component of various products for protecting poultry food. The present invention includes, but is not limited to, the prevention of food spoilage caused by klebsiella pneumoniae infection by liquid immersion, spraying, use in combination with synthetic ingredients, and the like, and is particularly suitable for cooked or non-sterilizable foods. The liquid soaking and spraying forms comprise but are not limited to food degerming agents, food disinfectants, food preservatives and the like; synthetic components of the present invention include, but are not limited to, benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, calcium propionate, and the like.

(7) The Klebsiella pneumoniae RDP-KP-20007 can be used for preparing a composition, a reagent or a kit; the kit can be applied to the rapid detection of Klebsiella pneumoniae, and comprises but is not limited to the detection of Klebsiella pneumoniae in a target sample in the form of test paper, a kit and the like, or the screening of target pathogenic bacteria in a clinical sample, so that the detection sensitivity can be effectively ensured;

(8) the Klebsiella pneumoniae phage RDP-KP-20007 can be used alone or in combination as a biological bactericide, a feed additive, or a therapeutic drug, a health product and a medical apparatus for bacterial infection caused by Klebsiella pneumoniae; the Klebsiella pneumoniae bacteriophage RDP-KP-20007 can be applied to treating or preventing infectious diseases caused by Klebsiella pneumoniae;

(9) the Klebsiella pneumoniae RDP-KP-20007 can be applied to industrial production, can be specifically amplified by host bacteria, can be highly purified by applying a standard virus purification method, and has excellent popularization prospect. According to the description of the invention and the common knowledge in the field, the Klebsiella pneumoniae RDP-KP-20007 or the composition thereof can be prepared into various products applied to the aspects of medical treatment, detection, disinfection, food protection and the like for industrial application by the technical personnel in the field. The product form can include, but is not limited to, the carrier carrying, the concentrated injection or the medicament soaking and the like, and the product is applied to the controlled host body surface, the oral part, the rectum, the inner pleura and other parts; as one embodiment, the carrier-borne form includes, but is not limited to, oral aqueous carriers, oral anhydrous carriers, cream formulations, and the like; concentrated injection forms include, but are not limited to, vaccine injections, pleural cavity injections, transvenous injections, etc.; dosage soaking forms include, but are not limited to, aerosols, rinses, and the like.

Drawings

The above and other features, properties and advantages of the present invention will become more apparent from the following description of the embodiments with reference to the accompanying drawings:

FIG. 1 is a plaque map of bacteriophage RDP-VP-21010 of the present invention;

FIG. 2 is an electron micrograph of bacteriophage RDP-VP-21010 according to the present invention;

FIG. 3 is a test chart of in vitro bacteriostasis test of the bacteriophage RDP-VP-21010 of the present invention.

Detailed Description

The invention is further illustrated with reference to the following figures and examples. The following examples will assist those skilled in the art in further understanding the invention, but are not intended to limit the invention in any way. It should be noted that variations and modifications can be made by persons skilled in the art without departing from the spirit of the invention. All falling within the scope of the present invention.

The method separates Klebsiella pneumoniae BK-20007 from diseased white-feather chickens in Qingdao, i.e. Mexico-farm, determines pathogenicity and drug resistance of the Klebsiella pneumoniae BK-20007 through experiments, separates a lytic Klebsiella pneumoniae phage RKP-KP-20007 from livers of the diseased chickens by taking the BK-20007 as a host, and determines genotypes of the RKP-KP-20007 through a whole genome sequence.

Example 1 isolation and identification of pathogenic Klebsiella pneumoniae BK-20007

Sampling the liver of chicken with Klebsiella pneumoniae bacterial disease, inoculating the liver to DHL culture medium by adopting a sterile operation method, and culturing for 18-24h at 37 ℃. The Klebsiella pneumoniae forms a light pink colony on a DHL agar plate, the large surface of the Klebsiella pneumoniae is raised, the Klebsiella pneumoniae is smooth and moist and is in a mucus shape, adjacent colonies are easy to fuse into a thick juice sample, and a long thread can be pulled out when an inoculating needle is used for picking.

And selecting light pink colonies, continuously streaking and purifying for three times, and performing biochemical identification. Culturing in a culture medium for transferring the Klebsiella pneumoniae from the DHL culture medium at 37 ℃ for 18-24h, producing acid on the inclined plane, producing acid and gas on the bottom layer and being negative in hydrogen sulfide. The biochemical identification shows that the test is positive in V-P test, positive in nitrate reduction test and negative in M.R, the test of Simmons citrate utilization is positive, the test of malonate is positive, the test of urease is positive, the test of lysine decarboxylase is positive, the test of ornithine decarboxylase is negative, and the test of glucose and lactose and the test of indigo substrate are negative.

Then, a single colony was inoculated into 5ml of LB broth liquid medium and cultured with shaking at 37 ℃ and 200rpm for 8 hours to obtain a uniform turbid bacterial suspension. Then, identifying through 16sRNA molecules to determine the Klebsiella pneumoniae, and naming one strain of Klebsiella pneumoniae as BK-20007; and the pathogenicity and drug resistance of BK-20007 are determined through experiments.

Example 2 isolation and identification of Klebsiella pneumoniae RKP-KP-20007

The liver sample for the experiment is collected from the sick chicken in the Qingdao, i.e. Memo-broiler farm in 2020 year and is used as a sample for phage separation.

(1) Isolation of phage RKP-KP-20007:

soaking liver 10 mg in 10ml LB broth overnight at 4 deg.C, centrifuging at 10000rpm for 5min, and filtering the supernatant with 0.22 μm microporous membrane for sterilization. 3ml of the filtrate and 3ml of the culture of the host bacterium in the logarithmic growth phase were taken and added together to 20ml of autoclaved LB broth, which was left to stand in an incubator at 37 ℃ overnight for the propagation of the phage which may be present. Taking 3ml of culture solution, centrifuging at 10000rpm for 5min, and filtering the supernatant with 0.22 μm microporous membrane for sterilization. The filtrate was assumed to contain phage. The culture medium is diluted with LB broth in a gradient manner, and is cultured with a host proliferation solution in logarithmic growth phase for 19-23h at 37 ℃. If the transparent plaques appear on the double-layer plate, the existence of the phage is proved, and if the plaques do not appear, the existence of no phage is proved, and the rescreening is needed.

(2) Purification of bacteriophages

The phage obtained by separation is not a kind of phage, so further purification is needed, bright, smooth and small plaques are picked from a double-plate with obvious single plaques, the plaques are placed in physiological saline, a pipetting gun is used for repeatedly blowing and beating, a 0.22 mu m microporous membrane is used for filtration and sterilization, LB broth is used for gradient dilution, and a gradient preparation double-plate capable of obtaining single plaques is selected. Repeating the steps for 4-5 times until the obtained plaques on the double-plate have the same size, shape and definition, and finishing the phage purification. The results are shown in FIG. 1, which show that the plaques are consistent in morphology, size and definition and are typical lytic phages.

(3) Determination of phage titer

Single plaques of the purified phage were picked and added to LB broth, together with the culture of the host bacterium in logarithmic growth phase, and cultured at 37 ℃ for 6 hours with shaking at 170 rpm. Increase of phageCentrifuging the culture solution 5ml at 10000rpm for 5min, and filtering the supernatant with 0.22 μm microporous membrane for sterilization. 10-fold gradient dilution to 10 with LB broth¹⁰Get 10 times⁸、10⁹、10¹⁰Double-layer plates were prepared with 0.1ml of the dilution of the double dilution and 0.1ml of the host cell growth medium, and the titer of the phage was measured.

Wherein, the titer of the phage (pfu/mL) is the number of plaques multiplied by the dilution multiple multiplied by 10; the titer of the phage can reach 10 by determination¹¹Pfu/mL. The phage has an optimum temperature of 37 deg.C and titer of 10¹¹pfu/mL, the phage can be stored for a long time at-80 ℃, and the titer is maintained to be stable.

Example 3 morphological Observation of phages

Applying a phosphotungstic acid negative dyeing method: phage multiplication solution 20. mu.L (titer 10)¹¹pfu/mL) was dropped on a paraffin plate, and a copper mesh was placed thereon for 10min and then removed to adsorb phages. Drying at room temperature for 2-3min, dyeing with 2% phosphotungstic acid water solution, sucking water after 2min, naturally drying for 5min, and observing phage morphology with a microscope.

As can be seen from the electron micrograph (FIG. 2), the phage RKP-KP-20007 has a icosahedron head, is three-dimensionally symmetrical, has a head length of 72.640nm and a tail length of 177.797nm, belongs to the long-tailed phage family of the order of tailed phage according to the latest classification and naming of the phage.

Example 4 phage genome sequencing

After enrichment culture of a single phage, centrifuging for 15 minutes at 8000g under the condition of 4 ℃, adding 10% PEG8000 and 0.5M NaCl, standing overnight, adding equal amount of chloroform, mixing uniformly, standing for layering, centrifuging for 10 minutes at 5000g, removing a chloroform layer and a PEG layer, adding restriction endonuclease for digestion treatment, suspending the phage under the condition of gradient density cesium chloride, dialyzing for 3 times by TM buffer solution at the later stage, and performing whole genome sequencing by Chimona genome biological sequencing company. The whole length of the phage genome is 1251bp, and has no virulence genes and lysogenic genes.

Example 5 optimal multiplicity of infection (MOI) assay

MOI means number of phages at initial infectionThe ratio of the amount to the number of host bacteria, 0.5ml of phage multiplication solution (titer 10)¹¹pfu/mL) was diluted 10-fold in LB broth, and 0.1mL of the diluted solution and 0.1mL of the host cell growth solution (10 mL) were each diluted at an MOI of 1000, 100, 10, 1, 0.1, 0.01, and 0.001, respectively⁶fu/mL) was added to 5mL of LB broth, and cultured at 37 ℃ for 8 hours with shaking at 200 rpm. Centrifuging the culture solution at 10000rpm for 5min, and measuring the titer by double-layer plate method, wherein the combination with the highest titer is the optimal infection complex number. The results are shown in Table 1.

TABLE 1 optimal multiplicity of infection test results

As can be seen from Table 1, the optimal multiplicity of infection for bacteriophage RKP-KP-20007 is 0.01

Example 6 in vitro bacteriostatic experiments

The titer of the diluted solution of the phage is 10⁸、10⁷、10⁶、10⁵、10⁴、10³、10²、10¹pfu/mL) and host bacterium proliferation solution (10)⁵fu/mL) was added to 100mL of LB broth, cultured at 37 ℃ under 180rmp, and 3mL of each was taken every 5min to determine the OD value. The negative control group was 100ml of LB broth; 2ml of host bacterium proliferation solution (10) was added to the positive control group⁵fu/mL). The total time is 16 h. The results are shown in FIG. 3.

As can be seen from FIG. 3, the titer of phage RKP-KP-20007 was 10⁴And the inhibition of the host bacterium BK-20007 in vitro can reach 15h, has extremely high production value, and can be sterilized by a low-concentration phage preparation.

Example 7 phage lysis Spectroscopy assay

And (3) carrying out host spectrum determination by adopting a spotting method. Adding 0.1ml strain cultured to logarithmic phase into warm semisolid culture medium, mixing, pouring into prepared LB agar plate, solidifying, and collecting 0.01ml titer 10¹⁰Dripping fu/mL phage on the surface of the upper flat plate, drying, culturing in an incubator at 37 ℃ for 4-6 h, and observing lysis conditionThe method is described. The host ranges are shown in table 2.

TABLE 2 bacteriophage lysis Spectroscopy test results

Klebsiella pneumonia number	Cracking property
		BK-20001	-
BK-20002	+
		BK-20003	-
BK-20004	-
		BK-20005	+
BK-20006	-
		BK-20007	+
BK-20008	-
		BK-20009	+
BK-20010	+
		BK-20011	+
BK-20012	-
		BK-20013	+
BK-20014	-
		BK-20015	+
BK-20016	+
		BK-20017	+
BK-20018	+
		BK-20019	+
BK-20020	+

Note: -the phage do not lyse; + phage lysis

20 Klebsiella pneumoniae stored in a laboratory are selected, the cracking spectrum of RDP-KP-20007 is detected by a spot method, and the strains are separated and identified from livers and dejecta of broiler chickens and meat ducks which are ill in Shandong, Henan, Liaoning and the like in 2019-plus 2021. Serotypes, identified by the K antigen, are of the following types: k1, K2, K3, K5, K20, K54, K57. As can be seen from Table 2, the phage RKP-KP-20007 can lyse 65% of Klebsiella pneumoniae.

Example 8 phage 80 ℃ Hot air treatment experiment

Taking phage multiplication liquid (titer 10)¹¹pfu/mL)1mL, treated in hot air at 80 ℃ for 10min, 20min and 30min, respectively, and the titer was determined. The results are shown in Table 3

TABLE 3 phage 80 ℃ Hot air treatment results

As can be seen from the data in Table 3, the phage RKP-KP-20007 can survive for 30min at 80 ℃ and the titer can reach 10⁷pfu/mL。

Example 9 drug susceptibility of host bacterium BK-20007

The drug sensitivity of the host bacteria was determined by measuring the Minimum Inhibitory Concentration (MIC) of the drug by the broth dilution method. The results are shown in Table 4.

TABLE 4 drug sensitivity test results of host bacterium BK-20007

Note: r is drug resistance; i, intermediary degree; s: sensitivity of

As can be seen from Table 4, the host bacterium BK-20007 is resistant to 10 of 16 antibiotics and has strong resistance, and RKP-KP-20007 can solve the problem of resistance of BK-20007 to the above antibiotics.

It should be noted that the specific embodiments are merely representative examples of the present invention, and it is obvious that the technical solution of the present invention is not limited to the above examples, and many variations are possible. Those skilled in the art, having the benefit of this disclosure and the benefit of this written description, will appreciate that other embodiments can be devised which do not depart from the specific details disclosed herein.

Sequence listing

<110> Ray union (Qingdao) bioengineering Co., Ltd

<120> high-lytic Klebsiella pneumoniae RDP-KP-20007 and application thereof

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<170> SIPOSequenceListing 1.0

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ccagtatacc aagttttggc gtggattgca actgaaattt tctaggatga tatggaggac 4260

ggatcctttc ctttattcgc gcgatgcgcg ggcgcacacg aataatataa aatgagggag 4320

ataagcaaat aaaattttcc agtttttatt gttttgatga tccagatcaa gttactgttg 4380

attataataa aataaggttg acatagctgt gcctatttgg tataatatat gcctaactgg 4440

aggaatatat gaacgaatta gacctgattg ataatatcta tagtatcctt gataacgagg 4500

gtgaagaaga ccttatgttt aataatgcta ataaggcaag cgagcagttt cctacacaga 4560

gggacatgat agctggagag gtttctaaat atgtggtggc acaggagctt ccagcatacc 4620

tattgacggc gcataatagg ggggagatac acattcacga tatggactac cgcgcacaag 4680

ggtatactaa ctgctgcctg gtggatttag cggggatgtt taagaatgga actaaaattg 4740

gtggagcaga gattgaaact ccaaagtcta tctctactgc agctgcggta actgctcagg 4800

ttatcgccca ggtaagctca tgtcagtatg ggggtacgtc tatagatcgt attgacgagg 4860

tctttgcccc atatgtccgt aagtcctatg ataagcactt agctattggc cagcgttggc 4920

tgcacgatag taagaaggct gcggtatacg ctactgaaat gacggagaaa gaagtatatg 4980

atgcttgcca ggggctagag tatgaagtta acactctatt caactccaac ggtcagcagc 5040

cctttgtgac atttgggttt ggtctaggag aatcctggga ggcacgcatg ttgcagaaag 5100

ctatgctgga agttcgtata agaggcctag gtgcttcagg gcatactgct gtatttccta 5160

aacttatttt tgcagttaag gaaggactca ataagtcccc aagtgatcct aactacgata 5220

tcaaacagct ggcgctcatc tgcacttcta agagaatgta cccggattac gtgagctatg 5280

aaagagtatc ggctgttacg ggtgatttta agttccctat gggttgtcgg tctttccttt 5340

cggctattga atcgggagaa actgctgggc gcaacaacct aggagttgta tccattaacc 5400

tgccgctagt tgctgtagag tctgagggat gtttcgatag attctggaag ttgttggacg 5460

aatacattga taaagcgatg gctgcccacg attgggctat tgagcggttg aagcgtgtgc 5520

gtgctaaaca ggcaccaatt ctctatatgc atggagcctt tggggtaaga ttaaaagcca 5580

atgatcttgt atggcccatc tttgagggca gggcatcagt gtccttggga tatatcggta 5640

ttaacgagct gattgaggta atgtttgagg ataccgaccc tatgtctcca cctgcggttg 5700

aattttcagt acaggttctc aaccacatga aagatcgttg caacagaaaa gctgaggaaa 5760

ctaatcttgg gttcagtctt tatgctaccc cgagtgagtc cctgtgtaac agattcaaca 5820

ctaaaattgc cgaacagtat ccagagtatg actggctaac ggataaaggc tacctgacta 5880

atagtcacca cctggatgtc cgtacaaaag ttgcccctaa cgtgaagttt gattatgaag 5940

ctaattttac taccatcgcc aatgggggta atatatcctt tgtagaactt cctgagatgc 6000

gtaagtttat ctctgcacta gagtgggttg ttgactatgg attaagtaag tcccactaca 6060

taggggtcaa cattccagtt gatgaatgtg aggggtgtgg gtatttaggc gaatccgtat 6120

ccggagagca tggttttgta tgcccccaat gtgggtccgg gaatatctca gttacccgtc 6180

gtgtttgtgg gtacttaggt agtcctggta gtagaccctt taaccccggt aagcaacagg 6240

aagtaatgca acgggtcaag cacatgaatt tgaaataaat cacttgctaa acacctccgt 6300

ttttgatatg atagttgtaa ttgagaaacg gaggatttat gaaaatccat aaaactgatg 6360

aaaagcgtat ctactttatg atggactctg gagcatacgg atctatttcc cgagaagacg 6420

tggtaaaact tctgcgatgc cgtaaccact tgtggaaaga taaagtcgat cccagaacct 6480

ctgagtgctt gtccgaaaag gcggagcagt tgcggaaaga agaaatgaga aactatatgg 6540

agttactgta atgcgtagat tgattattgt aagtggtgct gggttgagcg cagatagcgg 6600

agtccccacg tttcgtaagg gtgctgtcac cccactgtgg gataaataca agctaactga 6660

agtgtgcaac atccaggcgt tcgataaggg gtttcattat ctggacgacc ctatgccccc 6720

gttggaagcc ctttctgagg gtactgatga cgagcctagt cgtaacctgt atgaactgac 6780

ccatgagttc tacaacatga ggcggcaaga gctaggtacg gtggagccta acattgctca 6840

cttgagaatt gctgagtggt atgaacgctt cccaggtcaa gtcgttaact tcaccactaa 6900

cgtggatgat ctgctagagc gtgctggcat tccccatgat gatgtgatcc atgctcatgg 6960

ctacctgacg gagataatgt atcgccgagg taaagatgtg atcgtggaag atatcgggta 7020

cactgcggtt gattaccgta agtatgagtg ggttaagcct gcaattacgt tcttcgggga 7080

aactgctccg tggtatatag ggcagatcaa cctgtttgat accctgacaa cccaggatct 7140

ggtaatcgtt gttggtgcca gtaaccaagt aatcaacttt aattgggaac tattcccggc 7200

ccatagtcga ggtactaagg tgtgggtggt aaacaacggt attaattacc tagagcagag 7260

tttgtatgaa gaacgtggga tccctgtctg gtatgatact gctgctaacg tgtttagcaa 7320

caaacatttc ataggtcaag ttgaggcttg gctggaggag aaaatttatg taccatcccg 7380

atgatatcct gttatggcct aacggtagtt ggtgttatcg cagtgatgta caagatatga 7440

gtcacctatc ggacgactat caggttttac gagcggactc tgagcagtgg cacgaattca 7500

ttcaaatggg agaagaatat gctggtcaat gaaaaggttg ttaatgaagg ggttgggcta 7560

gttccctggg ctgaaattcc tttggacgta aaagagtctc tactggacca tcttcgtgtg 7620

tggtgcgata atatggaggt atacttcgat tatgacaaca tgcaccttgg gctatgggtt 7680

cctatggacg aagatcaaga tgaagtccta gactggggcg atctgactga gatggggctg 7740

gtatttgcac taggctacgt gtgtctgctg cgtgagtcct atatcccggt tggggttaca 7800

ggtgtttcag caggtatttg ggtcggacgt aatgaagatt attatgctcc ggaaaatatt 7860

aacagttgga tccaggtgct gcgtcgcttc ggtttccaag ttgaagggtt gactaaatga 7920

gtattcctaa aatggaacgt atctcctggg cggatatccc caaggaattg attgatgtag 7980

cagagaatct gctgcgaacc gcgttgaggg acgaggagct ttgcttcatc atccagcatg 8040

acgtgtgtgt tggtttgtcc aaaggtagtt tggcccagga ttatgagatc ctctttgatt 8100

gggatgacct ctcggacttg gggctaatgg ttctggtgaa caacgttgtg ttccacccct 8160

ctaactttgc agcattccgg gaaccagggg caggtatttc tccggggttc ttggtagctg 8220

acgagccttg gacgtatgcc ccagagattc ttcgtgaggg caaacaaaat gcctcttcta 8280

actcaattaa tattatgggt tggaatgcct agttgaacac ttagaccagg ggattatcct 8340

ctggtctttt ctatgtttaa acccagttac ctaccacgta tttaaatatt ttacttgcaa 8400

tctcgccacg atttttatat aatatattca taggttgaga gaaatgatgt gagttacgaa 8460

actgacataa ttcctctcat tcacttccga gcatacagaa cagtccggct gctacatgct 8520

tggttgggtt tggcttattg gaaaattgat tccgaacgga attatagata attgatctag 8580

aatgcgggta agagaggttg gcatcgcgag gctctcagat atttgttcgt tagtcatgtg 8640

gagcaaatag caccgcggtc tgaaatgacc aagaagtgaa gctgtaagta gcaacgtacc 8700

tctgcgcaat agcgacgaat aggggtcaac cacatggagc ttagcggcga ttacatgctg 8760

tgtgggagtt gtgcgaagcg gccagttcta gcaatgagga agtgaccacc cctccatcta 8820

taaggaaatt tgttgagtca gtggactttt aagctgttct atccttgata gttcgagatc 8880

gctttattct tcaacatagg agaaaacgta atgttttcta ttctagaagg acacgcgggt 8940

ttttcccgcg atcccgcttc cggcaattgg aaggaagtga agacaactga ttaccttttt 9000

gcgaaggagt tttctcacga gcatccagaa ggtaagccag cctcaatgcc ctacaaattt 9060

aacgtagtgg atacggttga tccaaaaaat cttaatgaag cgtatgagct gatggttcag 9120

ctcactcaag atccacatct cgtagcagta cgaggtacat gcttagttgc agagaaggcc 9180

gtgcgtcgta aacgtactaa cttcaaaatc gaccataaga gcaatattat tgctatggac 9240

gtcgatggaa tctccgatac tggaggatgc gacaaatttg acatcgtggg gatgggacgt 9300

catgttatta agttattaaa tagcatcagc gaggacatgt tcccgcttaa cgcagggttt 9360

attgcccatg cgtcgtcttc ggctggaatt aagccaggga ttcgtatgca catgctatta 9420

gagagtaata ttcctgttac tcagggtcag ttaaagtttc tatttacgtc tctcaacgat 9480

agctctcggc agaagtatgg ttttgatatt gccgacttag cttattattc atccgtacag 9540

ctacactatt tcgctgaccc gattttccgg gatcagttta ccgatccgtt taaagcggag 9600

ggtaagccac gtctggttaa agttaatggc gctaggattg aactgcccag cactatgcca 9660

gattacgaag ccactcgcgg ggaatttaaa gaagaatttc tgtctttact caatcagatt 9720

aaaggcaagc gtgtggcctc tgagaaggtg gagcaaacta ttgcagagct ggaagaagca 9780

gacgatggcg tttatctgcg tattattcct aaactgtacc acagagcgct ggaagacggt 9840

gttgatttcg catggcttga gaaagagatt acctcggcct tatccgatta catcaacacg 9900

aaggataact cccgtagtct tcaggactat tttaacaacg ggcgtaagca ggcgttaaaa 9960

gcgtttgtga acaactcgat gcgagatatt ccggagtcga atgttaaagg cgtccctgta 10020

cacaagttga cctctgatag ccccgatggg atgaactatt tgaagatcaa ccgtccaccg 10080

ccggaaggtc atctaacgtt tattaaggcg tctctaggta ctggtaaaac caccgcagtg 10140

acaaagtggc tagaacgtga tcagctgaaa ggtaatttcc ttgcagttac gaacacacgt 10200

gccctagttt catctaatgc taagaagttt gaagccggac agtatgataa gtccgtagat 10260

atgttaaact tcaaacgcgg tgctattgat cgtatgtcca ccactattca ctcaatccac 10320

aagtttaaaa actttgttgg acagatcgat gttatcttta tcgatgagtg cgacgcagtt 10380

atgaatgacc tgttattcgc tccagttgtc aaacaacgtc gtgagtgtat ctcagttctt 10440

cgtgaaattc tgctatctgc aaaagtcgtt atcctgtctg acggggatat cagtgcggaa 10500

accattgagg catatggatc tctcatagat tttgacaagc cggtctctta ttataaacat 10560

catcgtaaga tgctctcgga tgctcaggcg tatgagttcc cggatgaatc tagtatttgg 10620

gttgccctcc aaacgtccct agagatggga gagaaatcta ttctggtgtc cgactgtggg 10680

ccggatgagt taaacgagaa aggcctgacg ttaagaagca atacaggtgc gattgttaaa 10740

gagattcact caaactctac atctgactta gatattcgtc gtattttaga ttatacaacg 10800

aatgagctaa ttgaacagca gattgattgt ctactgtgta gtccgtcggt aacgagtggt 10860

gttgacttca actacttcga caacgtattt gttattactc gtacagctaa ccaggcgcca 10920

aacatgcgct tccaggcaat caggcgcgac cgaggagcta agaatatctt ctatttcatc 10980

gataagtcca ccagcggatt ctctgcgggt tcggagcagt acaacattga tgagggttgg 11040

atggagttag cccagcaact ttacgttaaa cgtcgtgagc tagagtcccg taactttatc 11100

agcacattac gatactatct gctggatcaa ggggcaacta tcgatatctt cagcgaaagc 11160

tggggtaaga ttgatagctc agccgcagag tatactgctg aacgagtttc tgctattttg 11220

agcagtaccc cggattggtg tgcaccccgc catgcggacg catacgaagc caagctaatg 11280

ctagtcaagt atttccacct ggactctatt aagagtatta cacaggaaca tgcagagatg 11340

tggattagca agaaacctca caagcgggcg gagttcttcc ataaacttca agatatattc 11400

tggaaggata ttaagaagtg ttctaacgtg acgattagcc cctttattga agccctgaag 11460

aaacacaaga aggacttctt tattaggacg ggacagtctg ccaaccctaa gtatgcccgt 11520

atgtacttaa cccaaatggg tattaataag gaaatggaga cggaacagat cgtagactgg 11580

tatcgaacct actgctctat cgagggtatc tctgtaccgt atgagtttat gacggacgag 11640

gagaaggcgc tggccgatga agcgcaaaac gaacttggag tacgtaatga gcaagcgtga 11700

tgcccgctgg gagacaagga agtttcccaa acgcgatacg aaagcacgga aagccaaaga 11760

gatagagttg tgtagggtaa tacctattcg cctagcacag atgccaaata tttatgactg 11820

gctagaagct cagcgaaaga cacgcctttc tatacgcatc aacatggaac ttaacatggg 11880

gtacaagagt ctatctgaat tcatgcacgt tgctttcgac cctacgttct atgaaaatcg 11940

cgattgctta gaagctaaat ctgtattata atagtttcat aaattcgaga gaggataaag 12000

aacatggcaa tccgcaaaaa acttcatgcg aatagcatcc cggacgaaaa gtttaaggaa 12060

gcgattcagt ggctagaaga tggcaagacc aagaaaggcg cttgcgaaat cctcggagta 12120

gcatccaact ccacgatgga acgtttgatc gaggaatgga aagataacca gcgtgtttct 12180

gccgaaatgc gtaaaaagaa acgtggtact aaaatcgaag gggctgagct ggccaatgtt 12240

atcgattcgt atctgtctgg tgatagtttt gaggcaatcg ccgagcgctt ctaccgttcc 12300

gcaaacatga tccgaatggt tctgtctgct cacggtgctc tgctccgtgt taatggtgaa 12360

gtagacccac tcttccctcc tgcgattcca gaagaatcaa tgaaagaggt atttgaagta 12420

ggcgaacacg tttggatccc agggtaccag tgtattggtg aaattaagaa agctctggat 12480

aacccggtag gagcttaccg tatttacttg ctgtctgaat ccaaacagca gtatgttaac 12540

tacatgtatt gggatatagc ttctgtagaa catctggtag cacttggtgt tgatatcaag 12600

tctctgggtt tcaagtggag caaagaagac gtagctgaac tggttaataa tgctgtaaaa 12660

gcagccctaa aattagagaa gagaggcaaa ggtgaataaa tatcaactcc tgaacttatt 12720

ccagatctat tccgaaggtg ctacagctat ccgggatctg cactacgcag ttcccatgga 12780

cgaagcagaa gataacggct ggctcaccaa gtacgatcgt ggtttgctga agatgtatcg 12840

tttgtccccc aatggtttgg tagctgttaa ccaaatccta gaaaattctg tttgctttgc 12900

agctcagtaa cttgttataa tattctcata gtttgaaaca aaacttaaaa actcttttta 12960

acaataaata aggaagtaat aaatatgtct actccaactc aatggtctcc tgaactcgaa 13020

gctgaactga cttctgccta cgtcgccaaa atcgaactct tcccggaaga tgaacgtcct 13080

ggcgtttcca tggagatcgt agctgagatc gctaaagagc acggtgtttc tccgaacggc 13140

cttcgtatga agctgtccaa agctggcgta tacgtcaaga aagaagccgg taagtctacc 13200

actaaaactg gcggtgatgc tcctaaagct ggtggccgta cttctaagtc tgatgctcag 13260

gctgagctgc gcgctgcatt taacgacgct ggactggaag atggcttcct ggacgaatcg 13320

atcgtggaca aactgaccgg taaagctgcc tctcacctgg ctgaagctat ccgtaaaatc 13380

actaaataag agggtattgc aatgaataga gcacaagtcg tagctatctg tgaaaaacac 13440

ggtgagtttt gcatgcaata caccaaactg cgtaccaagg gggtaactta cctctacggt 13500

acgactgagt tcgatcctaa gcaagataaa tacctggccg agcgaatcgt ccgtgaaggc 13560

ctggaacccg ctgacaaaga tcatatcctg gtctttagcc gctctagcga taaattccgc 13620

tatattccga ttgcgaatat taagcgcatc accagcctca accaagaact tgatcgagct 13680

actccagtag gtcgttaaga cgcaatcagc cccttcgggg gctttttgtt tatctgagaa 13740

caataaaaat gaatcaaaac atttgtcagg attacgaagg acatattgat gatcagtccc 13800

acgttatctt tgaagatgaa gggcgacaga ttcgtatgac tgtctcggag tttaggggca 13860

atttatactt tggtttccga ttatggttac tagatattga agataactgg ttccctacta 13920

aatcaggctt ctcgttccct tacacgttag aaatgactag cacgctgttc agggcgttta 13980

ctaaaatact aagcaattca gaggttcttc atgaagttta ccgtgaatct caaaagaccc 14040

aagccagtga cgactaagtt gctggctttt tctttaaaat ctcaattgct tagtgtttta 14100

aaccttgata taatattctc atagtttgaa ggagatcttt atgaaagatc atgaaattgc 14160

tcagctagtt aataagctga ccgaagctgc taagacgtat gctcatactc agcaattaag 14220

agcacacatg tctaaaattg tcaaagaggc gctaaagaat gcgaaagata acacttgatg 14280

cgtacttcag tcccccactc cagggccaag agttaatcct aacatggatt gaaaaagaga 14340

agggcaaaaa tgtagttcgt actctcgaag ggtataagct cctaaacatg tggtacgaag 14400

gtactgagtt gcgctgcgaa ctatacagcc ctaagtctga acgaaacgtg ataacacttt 14460

tctattatct ttgccgagat ttcaattggg aaggaaagac caagacattg tgtgaccact 14520

acgaggttaa ataatgcaac acgttaaaga atttatcaag ctgtgccaag acgcgtacta 14580

caaaggcatg tcgattatct ccgatgaaga gtatgatgcc ttaatccgtc gttttccgtt 14640

agaagatgaa atcggcccca agggtgacat acctcacctg ttccgtatgt actccttaca 14700

gaaagtgtac ccaggccgcg gcgaggaagt acccttccag ggcattgaaa cgccgaagct 14760

cgatggttgt gctatttcac ttctgtatat cgacggaaaa ttcgtttctg cgttaactcg 14820

tggtaacggt attctaggga acgatgtaac tcataatgtg aagttactga acatacctaa 14880

gaagatctct caaaagaccc cggtgcagat tactggtgaa gtacacatca ccaaagaagt 14940

tgagaacatg cgtaacttcg cctctggtgc tattaacctg aaagattctg gagagttttt 15000

ctcccgtatt gcagaaggtg gcctgatgtt cacggcatat agtattcagt gtgaaactgg 15060

caaagttggc ctgaccgcta ctttctgtgg agatatgcat atcctccagg gtgatggttt 15120

tgttacctgt ctggatatct ccagtcgagt agattggttc ccaacggacg gcgtggtggt 15180

tcgtatggac ggcaacaatc agtttaacgc agcaggttgg actaacaagt tccctcgtgg 15240

tgcgtacgcc atcaaagaag acgatgaagg cgaggttact acgctagaac gggtagaatg 15300

gcaagttggg gcttccggta aggttactcc tgttggatac ttcaccccgg tagtcatcga 15360

cgacgctgtc atctcaaaag ctaccctgaa taacgttggc tatatcactg cccttgacct 15420

agaaatcggt tgccagattc gtgtaattcg tagtggtggg gttatccctc gcatcgtaga 15480

acgcgtttac gagtaacact tgattcaata gatacaccgt gatgattttt taaagtagtt 15540

attgacattt tcatcgccag ggtgtatact attatcattc agttgaggga aagaaatatt 15600

tggtgagaga ctgagctaaa ttctgaaaaa tttcgattgc ttagtcctga ttttcttgct 15660

ataatattta tataaattga tgaggaagaa aatcaatgaa aattgaaatt ccactgaatt 15720

gcccctcttg tggttcgaaa ctggacttag ttaacgatca gttgttctgc cgtaacaagt 15780

ctatgtgtcc agctcaaagc agtaaattaa tcgagaactt ctgctcaaaa atgaagttaa 15840

agggttttgg cccacagacg attgctaaac tggagatcac aaaagtttca gaactctttt 15900

tcctgactaa agaagattta gtcagagctg taggtgataa agtcgccacg aaacttgagc 15960

tagagttgga aactaagctg agacaagatg ttgactttgg ttcggttctt ggatctctta 16020

gtatccctct tatcggtgaa gttgctgcta agaaattatc ccagctttac aacgatttcc 16080

aatctgtgaa agcggaaggt aaagctggag aaaacttagc ttcgtggaag aatacaccgg 16140

caggacagga cgtaattaat ctaccatgga aattcagtgg ggcgcgggaa actcaagtta 16200

ccccggctac tgaatccaac ggagttgttc tttgcattac tggtaagctc aacgacttca 16260

aaaatcgtgc ggacgctacc aaatatctgg aaagtcttgg gtatacggtg aaaacctccg 16320

tgactaaggc tgtaaactac ttaatctgcg aagatgaaac caagattggt tcttcttcat 16380

acaaaaaagc acaatcgctg ggcatcgaag tcttgacgat taaaattcta ctggagaata 16440

aataaaaatg gctaaattaa cctggaacga agaaatcact gcatccctga ccgctaaagc 16500

taacgctctg aacgtgaccg ttatctctca ggaagctgtt gctaacatcg ctgctgaact 16560

ggctgctgaa actggtaaag aagttaccgc tcgttcggtt ggttctaaac tgcgtaaaga 16620

aggcttcgaa gtgcagaaag catccgacgt aaccaaatct ccgtggactc cgggtcagga 16680

agatgaactg gttgcattcc tgaacgatca tccgggtcag tatacctacg ctgaaatcgc 16740

tgctgctgta gttggtggtg cttataccgc taaacaagta cagggtaaaa tcctgagcct 16800

ggaactgact gccgctgtta agccgactga aaaggccgct gctgtacgta gctttagccc 16860

ggatcaggaa gctgctttca ttaacgccgt tgccagtggc gcatccgttg aagcaatcgc 16920

tgctcagttc gaacgtaccg ttaagcagat ccgtggtaaa gctctgagcc tgctgcgtga 16980

aggccgtatc gaagctatgc cggttcagga agtctctaat gctaaggcac gtgaagacgt 17040

tctggaaggt ctgaatatcg ccgacatgac cgttgctgag atcgcagaag caactggtaa 17100

atccgagcgt ggtgttaagt ctatgctgag ccgccgtggt atctctgcta aggatcacga 17160

tggtgttgct aagcgcgcta aacttgacgc taaatccgcc aagtaattga tttgacctga 17220

ggggagagga attttgttcc tctccccttt ttcgtttaag tagacgctaa cgcggcgtag 17280

agagtatctt atgtataacg tccaagcagt agttttgaaa atgctcctag cctccgatca 17340

aaagcaggtg gctctagaga cattctctag actgcgcaaa gatcacttca atgacgcatt 17400

taccgcgatc taccaagctg tccagaatta ttacaaaaag cataacggaa tgccttcgtt 17460

agatgctctg atgctagagt ctaacagaaa cgcaaggttg tctcaagcac taactgtttt 17520

agcaaacact cagattccag acgttgacat atcgcatgcg attcatgtcc tagagtcgga 17580

atacacacag gatctattcc tgaatctgct agaaactgat gtgttgcagg atattaccat 17640

actggatcag ggagaattac ttgatcgagt agcggctctg cacatgaagc tagaggaacg 17700

agtaacaacg actggtaagg tcttcaacgc cgatactatg cgtgttttta agagaaaaga 17760

agactcaatg ttaaatctta tctctctcgg catctcaaac gaatttgatg ctcaacttgg 17820

cggaattgcc agaaaagaaa cactgctact cggtggatgg cgtggtacag gtaaatcaat 17880

catctgttct aacattcaag tagcccagta ttacaacggg gatatcgccc catatttctc 17940

catcgaaatg ccagagaatg aggtctttag acgtaaccta gccattatgg ctggtgtttc 18000

agctaaggct atgcgcaatg actccttaca aggtattgaa ctcaacaaac ttgcgaagac 18060

tcgtgcaaaa atgttcgaag gcggtctgga agtatataac gattttgtat cacgttatac 18120

gctcaacgag atgagtgact tccatgacat ggagactatg ctaatgcagg aaagacccct 18180

gcacactccg atgatcatcg tgtatgatcc ggaacttagt acagcaacca tcgatgttga 18240

actaactaag ctaacctcca agtatgggga taaggtaaca atcgccctgc tagactatat 18300

caaccaggta cgtttgccgg atacgaagac attagatatg tatgattgga agcagcagat 18360

ggttgtgtcc tctacgttca agtctacgtg ccaaaagcat aacgttgctg gtgtagctcc 18420

ttaccagatt gaccaacagg gtaacgcccg tatggcaaga ggtattctcg attcctgtga 18480

tatggctgca aacctaaatg ctgctaaaca gaacgagggg catgacggtg caatcaagtt 18540

tgacttcgta aaaactcgta actccgaggg tatgacattc atgccgaaga tcaactggaa 18600

ctcattgcgt atggatcaga cttctgatct taaactagag gacattcgtc agatggaagc 18660

agagtttgtt atcccacttg aaagcgataa accgaaagac aaaccaaaaa ggaaaaaggc 18720

ttcggatgag gatactaatc ccaccggaga atcctcaaga gacttatgag tagaataacc 18780

gagcttttag atctcaaagg gattgaatac agagatacgg gtggggacat cctcatccgc 18840

tgtctcaatc ctgaccatga ggatgcacat ccaagtttac gtgttgaccc cgattcaggg 18900

gtttttcact gcctaagctg cggatttggt cgtggtatac caagcatctt tcattacttc 18960

aatgaagaac agtacaggac gtctcctaga ctcctgaaag ttcgcagaat gattagtgac 19020

ctccgaactg agggtcgcag tctagaaatt ccagaatcag ccatgatatt cgaccaggat 19080

tttcgtggta tcaaagcaga gactttcaaa aagtactttg cattccaaca aacagaggac 19140

tgggaaggtc gtgtagtgtt tcctattacg gatgccgtag ggagaaactt attcttctta 19200

ggccgtaata tggatagctc tgcccctccg aaatatatga ttagacccaa gaaggtctcc 19260

ccaccaatct tccctgttcg ctataatacc ccagccctaa tcctagtcga aggtatattc 19320

gacatgttga atctagaaga taaaggttgc cataacgttt cctgttgttt tggtactcac 19380

cagttctcgc tagataacat tgctgataaa ttcatgccgt tccaaatagc aggtacgact 19440

cacgtagtca tcatattgga caatgataag tccggtaacg aggcatctaa gaaattagcc 19500

aaattaatcc gtgataagac tagaattata ccaattatag gtaacttctt gcttccagag 19560

gacaaagacc ctggagacct agatgctgaa gaagtcgacc agctcatcag aaacgtagaa 19620

atcttgattg ctgaacatgt caagatttga tataataatt gggtaagttt gagaagaaac 19680

actgacgttt tacttgctta cctaatagga gaaatcaatg aaaattgcag ttgtagacaa 19740

atcaccgaat aacgtccgct atcagaaaca cttcgaactc tttgaccatg aagttgagac 19800

cttctttatg gctagtgaga aagtaaccgg gcgactgctc aagaaacata tcactatcgg 19860

aacaccggag aacccgttca atccggaaga ttttgattac gttattctgg taggtgcaga 19920

cccgttcctg aagtttgcag ctaaaaaggg catttccgat tactcaggta aacgtgttga 19980

gcatgatggg tatgctaact ggattgcaag tatcagtccg gcccagctcc actttaaacc 20040

ggaaatgaag cccgtatttg aggctaccgt agagagcatc cacgccattc tcaatggtcg 20100

tgaaaaacgc tctaaagcag gtgattatcg cccgattcag tgcccggatg aagccgaggc 20160

atacgtgaag atggtgtata ccatgtgtcc tggtatgatc gcatacgact ccgaaactag 20220

tgcgctgtac tgccgagatg gttacatgct agggatctca atctcccacc aagagtatca 20280

aggcgtgtat attgacgcag acgtcatcac cgaaaatacc gtctattact tacagaaact 20340

gttcgatagc ccggaacatg gtgttgtgtt ccataacttg aagtttgata tgcacttcta 20400

ctgctaccac ttaggtttat cctttgataa ggcagcagaa gagaaacgcc tccacgatac 20460

catgctgatg cactacgccc tggatgaacg acgtggtaca cacggtttga agtctttggc 20520

gatgaagtat accgatatgg gggactacga ttttgaactc gaccagttca aggagacgta 20580

ttgcaagacg cataagatca agaaagagga tttctcgtat gatctcattc cgtttgatat 20640

catgtggcct tacgcagcga aagataccga tgcaacactg cgtctatcca acttcttcct 20700

gccaaaagtc gaagctaacc ctcgactgaa gtctctgtac tacgatgtac tgatgccggg 20760

atgtgtattc ctacagcgca tggaagaccg tggtgtacca atctccaaag atcgtctgaa 20820

agaggctcag gttcagttaa tgactgcgct acagctcgca aaggctaagc tgtatgagta 20880

tccagaagtt cgtaagctag aagaagatca aggctcggtg tttaacgcag cctctgttgt 20940

ccagctccgt aagctcctgt tcgattatgt tgggttaacc ccgacgggta tcatgacaga 21000

tacgggtgca gattccactg gcgcagatgc cctgaaagaa ctttcagacc aacatccgat 21060

agctaagact ctgctagaga ttcgtaagat ctccaagctg ctctcgacgt atatcgagaa 21120

gatgctgatc agtatcgatg ctgacggctg cattcgtact ggattccata tccatatgac 21180

tacatccggt cgtctgagtt cgtctggtaa gctgaacctc cagcagttac ctcgtgatga 21240

gtctgttatt aagggttgta ttgttgcccc tatcggttat cgcattatcg catgggactt 21300

aacaactgct gagatctact atgccgctgt actgtctggt gacattaaca tgcagcaagt 21360

gtttatcaac atgcagaacg acccggaaaa ctactcggac ttccacggtt caattgcaca 21420

catggtattt gccctgccgt gtaaaccgac tgaggttaaa aagctgtatc cagcactgcg 21480

tcaggctgca aaagcgattt cgttcggtat tctttatggt tctggcccgg ctaaagtagc 21540

agcgtcagta aacgaagctc tcctagaaga gcacatgaag actggtaaac cgtatactga 21600

gtgtactact ggggatgcga aagagtacat cgaaacctac tttggccgat tccctcagct 21660

taagaaatgg atcgataaat ctcactctca aatccagact aacggcttca tttacagcca 21720

ctttggccgt aagcgtcgtc tgcacaacat taactccgaa gaccgtggtg tacagggtga 21780

agaactgcgt tctggtttca acgccatcat tcaatctgca tcttctgata gtctcctgct 21840

aggtgctatc gataccgata atgagattcg ctctcttggt ctgcaggacg aaatgaagat 21900

tatcatgctg gttcacgact ccgtggttgc cattgttcgt gaggatttag ttgatcagta 21960

taacgagatg ctaatccgta acattcaggt agaccgtggt atcagtatcc caggctgtcc 22020

gattggtatc gactctgact cagaagctgg cggttctcgt gattactcct gtggtaagat 22080

caagaaacag cgtccttctg ttgcttgcat tgaggacaag gagtttgagg agaaagtacg 22140

tagtattatc ggtatggagg acttcgatta cgctgctatt gcggctaacg atgaaaacca 22200

ccctgatcac gataagtacg ccaatattaa gttcttgccg gaaatcagca aagatattgt 22260

caacgttcgc agggttcttg gtgcttaact ttagcttacc agtatatgct ttaagggctt 22320

atgatgtact cttccaaggg ggggagtaca ttgttatcca gacgagattt acaaggtatg 22380

tgctggacaa tccaagcctt cctgggacat tctctcagcg aaggcttttt ctttatggtg 22440

agcgggaaaa tttaccttac aagctctatc ccttaaagaa acagttcaag tacttatctc 22500

agataataaa ctctggacta aagcatttca tcgactccac aggtaagata gtaacatgga 22560

aacctacgac ttattacaac attatcacgg aacgcgttag aggatcaact agaatcttca 22620

acggaaagta ccagtgttat gttaagaacg taccataccc tttcttactt agtgaacctg 22680

ccaactatat ttcgtacgcg ttggttcgcg gttcaccagt tatttttgac acgcacgaag 22740

aggagccaga aactcctaga cttagagtta agatatgaag atagttatat ctaataaaat 22800

ctattgtaaa cccagcaacg aactgtggga atacttatta aaacacactt cataccagat 22860

ctttaaacct ggggcgaagt atcctctaat gttccagaac tcaggatcgg taggtaaaga 22920

aatcaagtgg ttccctgtaa cccgattaga tctcctagaa tctttcgggc aaaaagtgac 22980

agaggtcgtg gataaacgta ctctggttcc tgtggatatt ccaaagccat cgtttaccct 23040

gagacccggg gatcagctcc ctatatatga agactgtaat gatacgtgca ttattaatgg 23100

taagccgggg ttcggtaaaa caatccttgc tcttgctatc gcccataaac ttgggcaaaa 23160

aacgttagtt atatgtacca acactaccat tcgagctatg tgggagaagg aggtacgcaa 23220

gttcttcggg attgagccag gagttattgg gtctggcaaa tttaatatcg attctcccat 23280

cgttattagt aatatacaga cagttaacaa acacggagcc gctttggcaa aagaattcgg 23340

caccgttatt gttgacgaag tgcatcactg tgttgccacc acgttcacca agtttctaga 23400

gcagtcctcg gcacgatata aaatcgggct atccggtacg ttaaaacgta aggatgggct 23460

acaggttatg tttaaggact attttggaac gaaagtgtat agtcctccgg taaataacac 23520

tctgccacct actatccata ggtttgcgct aaaaacgcag gtttctggaa atatgaatgt 23580

gccgtgggcg ataagagcta acgatgtgta ttcgcagcca gagtactttc aacaggttgt 23640

tgacttgtgc gaattatatt caatggcagg tcataaagtc ctatttgtgt ccgatcgtat 23700

agatctgatt gagagagtta cgaacgcttt ggaactcagg ggtgtgaaga cctacacgat 23760

taccggtgta acatcgctcg atgataggga gcaagtacag attgacgtga ccaatgacgg 23820

tccgtgtgta ttagcggctt cccaaagcat cttctcggag ggtgtgtcat taaatgcttt 23880

atcgtgttta gtgttaggct ctttaataaa taacgaatct ctaatcgaac agttggcagg 23940

ccgtgtccaa cgtatggcag atgataagtt agacccaatc ctcgtggatc tgaagctagg 24000

aggtgtagga ttcaagcagg cggcaggtag agaagcggta tatcgtctca atgggtggga 24060

agttcttgac tttaacgaga agaacatggt aaacttagat aaaattctgt ttgctaagaa 24120

ccccaaagtt tgatataata tttatattga attgagagac agatttacaa agaagagtta 24180

agcaaatagt taaaaatttc agttgctgag tcctcaaaaa tacgatataa tatctgtata 24240

aattaatggg aacagcaact gaatcttcgg aaagtccgaa gcagaaaaat aaaaaactta 24300

gttgctaaat tctctcaaaa tggtgtataa taatcatgtt gttttatgat tacgaaaaaa 24360

tttacatatt agcgcgaggt aactcatcgc tgattgtaca gattatcaga cgaatggttg 24420

aagatcccga agctcatgtg atgttaacgg gtagatcatt tatcttgaac gaagatacaa 24480

tcgtttataa taaacgaaag ctgtcagacc gacagttggc tgagtatcta ggacttttga 24540

gttttagaaa ctatgccgaa tatagcttct caaaggatac atcactggat atgcaatata 24600

ttcctccgtg ggttcctaga gcagttatcg agcaccaccc actaatcgca atcaacaagt 24660

caaaattgac atttatcgag gaaaaataaa tatggctact aaatcttggg gttctactac 24720

tggcggttct aacggcgaca aactggacta catgaagttc aacaacggta agaacgttgt 24780

acgtatcgtt tccggcgttc tcccgcgtta tgtgtactgg attcagaaca aagaaggtaa 24840

accggctccg ttcgagtgcc tgcgtttcga ccgtgagaaa gagcgtttca tccgtggagc 24900

atccgatccg gttcacgaca tgggcttcaa agatccggag aagaaagatg gtaaggctca 24960

gccgctgcgt cctaagaaaa actacctggc cgttgttatc gatcgtactg ataacaaact 25020

gaagctgatg gaagttaagg caaccatcct gaccggtatc cactccatca tggcccagct 25080

gaatctggaa gatccgggtg agatcgatat cactatctcc aaatctggta ctggtttcga 25140

tactaagtac gatgtacagc agatcgcagc tatgcagttc cagatggcta aaaatcagcc 25200

gggttctaaa gaggccgccc tgcatgaagc cgacgttgct ttgattggcg aggctctgta 25260

caacgaagcg gacgaattcg aaggcttcga aaaagtgcct aaactggatg ttacctaccc 25320

ggttccgtcc tatgacgagc agaagaaagc aatccaggca tggctggaag gtaagaaaga 25380

tgaggagggc gatgaatcta aaggtaatga aggttccgca aactccggta acatcgatca 25440

cgaagcagct tctgacctcg attaatccaa acaaggggag cttcggctcc cttttatttt 25500

gactatgaaa aacaagttat ttgagatgta ttctacttgt ccagaggatt tcgaacgatt 25560

cgtagcagct ttacgagaga cctataggta tgatcccacc actggtgtta tgtctagact 25620

aaagtcctcc ggaggcgcta gagctggctc aactgttgga tctgataatg gtaaaggcta 25680

tttacgctgc tcgttccaac gatcgttata cttagtgcat atcttgatat acgcactagt 25740

aacaggagaa atggtcgaga ctatagacca tcgcgactta gataagaaga ataatgcttg 25800

ggataacctg aggcccacca ataagtcagg taacgaaaag aatactaccc accgtgtaac 25860

atctaccaca ggtgttaaaa atgtgtattg gattgatgaa cgaaataaat tcagagtcca 25920

atttaaggta gaaggtaaaa caaaaacctt cggttactac accacgttgg aagaggccgc 25980

gcaagttgcg aagtccaaga gattggaact tcatggagag tttgctagat catgaaaatc 26040

cttttttcag cagatactca cattaagcta ggacagaaaa atgtacctag tgcctggcaa 26100

gagaatcgct tccttatgct aggagaacgt ttagataata tcttcggggc aaccggttgt 26160

gatcttcaca ttatcggtgg cgacctaatg gacgttgcag atccttcgtc tgaagaagtt 26220

gagctaatgt ttgccttcct agcaaaatta ggtcatccag gtattatcta cacaggtaat 26280

cacgaactta aaaccaagac tatttcctgc ctggatcact atgccgcagc catccacgat 26340

gctactaacg gactttggaa agtcgtcaaa gactacagat ctccagagtt cgatatcatc 26400

ccttacagca gccttcacaa agctagttgg aagcccagag tttcagacat ttgcttcacg 26460

catgtcagag gtgcaatccc gcctcatgtc gtaccagaaa tcgacctcga aagattcgtc 26520

gaacatgggt actccaaagt atttgcaggc gatctccaca gctacaagaa cagccaaaag 26580

atcggggacg ttgacctgct ctaccccgga tctccgctta caacttcgtt tcacagagaa 26640

aggacaaaag gaactaacgg agcttttatc atcgatacgg tcttgccaag agaccatgag 26700

cactaccttt cgtgggttga actgggagat cttccacagc tcatacgaaa aactattgaa 26760

gtcggcgagc caatggaagc cgatgcgtat gacagagtta tatacgaagt caccggcgac 26820

gtatcacaac tcaaaacgtt aaagaacagc gaactgttag ataagaagat caataaccgt 26880

gtcaccaaag atgctaagtt agatctagac gatatgtcac tgctacagga gctggatact 26940

tattttacaa acgtgcagaa actagacgaa gcgtctagaa ctcgcatatt aaagagagcc 27000

gctgagtatg tcgatagtaa ttaataaatt gacaatcagc cattttatgt cgtatgctga 27060

gaacgtggtg atcgagtttg ataatcaccg cgtaactcag ttaatcgggc gtaatgggct 27120

gggtaaatca acaattggta cagctctaga agagcttctt tataataaga actcacgcgg 27180

tatcaaaaag gacgacctgt ttaactggca tactggctcc aagtcctata cgctagaagg 27240

tcagttcacg aaagacggtg acgtgtataa cgtcaagaaa gttgtgaagt caaccgccaa 27300

agtaactctc actaaaaacg gtgaagatat cagcggacac accgcaaccc aaacgtataa 27360

gctgatagaa gaggtactcg cctgtgattt tacgacattt actaagctcg tatatcagtc 27420

agttggatcc agtctcgact tcctcaagac tacggatgct cagcgcaagg ctttcctcgt 27480

taacctgttc gaccaggaac aatataagga agtttctgaa cgtgttaaag cgggacgtaa 27540

agccgtctcg gcaaaactgt ccggattgga aggtagcctg cgaactgccc aatctatact 27600

ttcctcaaaa gcctcgcttg gcacacctca atcagagatc ccaatccctg ttttcgatga 27660

agagccacta gtcgaagaat taaccgaagc aaaagtcaag gtagcactgg ctcagaagca 27720

aaaagccagt attgcaaaac gtagctcttt ggacatggcc gtacaagctg ccgaaaaaac 27780

ttttgcacca ttcgaaaatt tacctgcgcc cacctcgaaa tctgaggaac tcctgagtgt 27840

tacgcgtaac ctaacggtcg tggcaactag agcggatgat ttgaagaaac gttactacga 27900

tttcaaaaat gcagcaggta aaactcagtg ttctgcgtgc ggaacccact tagacacctc 27960

cgccgctcaa gaggccatga gacgaactaa ggaggagtat gatccgctgt ataaagaacg 28020

tcaaaagctg gaagcagaag ttgaagaact taggaaggaa gatagggcgt ttaaggatta 28080

tatctctaag tttaacgctc tggaacaggc tcgcaaaaac ctcaaggaat ttgatgaggt 28140

caatggaacg caggatgaaa tcgtagatgc tagtggacta gctgaacgta tcaaagctat 28200

tgagtctagc attcgtcaag gcagatcttc ggtagaactt gcaagaaccc ataacgaatc 28260

agttgtacgt gaaaacgcga agtatgaagc taagcgtgaa cagattcaaa aggccgagca 28320

ggagtttgat aagattcaag ccgagttgtc cttagttgca gaagaagtag cggatctgga 28380

tatcttaatc accgggctga aagatctggt agggtataag ctagagcaca gcgtcaaggt 28440

atttgaagag atgatcaacc actatctctc tatcatgacc agcggtaaat ttgctctagg 28500

gtttgagttg gacgagacga agctacaggt tgtcatctac aatgatggta acagaacttc 28560

tatggtcaac tgctcaacag gtcagcagag ccgcatcaat atctccacgc tattagcaat 28620

tcgaatgttg ctttcaacaa ttagtaaggt taatatcaat ctgctcttcc ttgatgaagt 28680

tgtaagctat attgacccgg atggaattaa taccctcgta gaacttctac aggaagaaga 28740

tcagctgaat tcaatcatcg tatctcacgg gcatacgcat ccgtacgcac ataagattga 28800

ggttaaacaa gacgaagctg gcttatcaat tttggaggcc taatggccgt agatagtcgc 28860

gagaaaggaa aacgcgcgga ataccaaatc cgtgatatgc tgcgtaagta tacctccttg 28920

gactgggaac gtgttcctgg ttcaggagct tttggacagt cccactccct gaagggtgat 28980

gtgtatttac cacctagtgt aggtaaaatg agccaatact gttttgagat caaacactac 29040

gcagacgaga aatttaatag caatatccta aacgttggag aatcccaact agaaaaatgg 29100

tgggcccaag ccgcacgtga aggtgagcaa atgaacatga aacccgccct gatctttaag 29160

aaagatcgtg gtcaatggct tatcgctctg gatagtagcg accctatgat tgataacctc 29220

atgagtagag cacatttcat agtgaataaa cgtggaatgg aaattgttat cggtcttttt 29280

gagccgtggt taaacgcatg tgatatcgga gatttagtta aatgagtaaa tcctggggaa 29340

caatgaaacg tgaggcagaa caacgcctcg cctcacgccg taatcttatg attgttgacg 29400

gtacgaactt gggcttccgc ttcaagaaag atagtggcaa gcctattgca gcatcctttg 29460

caaacaccat caactctttg gcaaactcct atgacgcgaa gcatactatc gttctaggag 29520

ataaagggaa gagtatcttc cgtactaata ttttcccgga gtataaaggc aaccgagatg 29580

cgaaatacgc cgatcgctcc gaagcagaag tagaagcgga tcgccagttc ttcgagtact 29640

tagacgatgc gtttgatctt atcgcaagtc aattccctac tttccgaatc cgaggggtag 29700

aagcagatga tatggcggct ttcattattc aactgatagg ccaccactat gaccatatct 29760

ggctaatctc cacagacggt gactgggaca ctctgttagc tccgaatatc tcacgcttct 29820

cgtttactac tcgtaaagaa taccacgaga aagatatgtt cgacaaccat aacgtagaca 29880

ctgtggacca gttcatctca ttaaaagcca ttatgggcga tatgggtgat aatatccgag 29940

gtgtggaagg tatcggtgaa aaacgtggat acaatctaat ccgggaacat ggtagcgtgc 30000

tagatattat tgatgcgctg ccgctgccag gaactcaaaa attcgttcaa gcgctgaata 30060

aatcaggcga actcatggaa cgtaacctaa ccctagtaga tctcccaagt ttctgtggag 30120

aagcagttgc tgcagcagga caagatatct acgaccaatt tgttaaagac attatggctg 30180

ttgccacagg agaagtataa tgcgtattaa attatctcac cccgattgta aacctcacgt 30240

tggaagttcg gaagcagctg gtatggatct acgggcctac ttcggagatc gtgcttcaga 30300

cctactacgt gccatacctc ccggggagtc attgatgatt gataccggag ttgcggttga 30360

gatccccgaa ggctgggtag gaattgtggt tccgagaagt tctctaggga aacgtcggtt 30420

aatgattgcc aatacagtgg gggtgattga ctcggattac cgaggaacca tccagatgaa 30480

tctgttgaat atgagcaatg agactcagcc aattgataac ttcgagcgtc tgtgtcagtt 30540

ggtgatcgta ccccattata atcccaacga cattgaaatt gttgatagtc tgaccgacac 30600

tgatcgtggc gaaggtggct tcggaagttc tggtaagatg taaatagaaa aaccccagtc 30660

ggagcaatcc gctggggttt tgttttattc cactcctggg tcttctggca tttctacttc 30720

tggaatctcc acttttggca tttccagacg caggtcaatc caacgacctt ggggtatctc 30780

cataggttca ccagcgatga tattccctgt gttaatatca aatttacgag tgaacacctg 30840

tatgtttagc tccttctctt cttcattcca atccgattcc acgaagcaca acatattacc 30900

gttgtcatct cttggtaatt cgaatttcca gccttccgtg ttccagccta aactcccttt 30960

aatcgtatac ctgcctagtc cagtttttac agcaaataca ccttgagcct ctgcgttaca 31020

ccctacgtag cctcctacag tttccacacc tgtccagaag aacgaatcct ctttgctagg 31080

aatttctgcg atgagcttgg cgatagggga ggctttcttg acaaaaccgt taccgtctat 31140

agtaatacct gctataccgg actgaatatt aggcttgtta ccttcatggt atagggcaaa 31200

ccaaggtctt ggactagttc ctgagtctgc tctcagtgag cgaacaaata ccccaagtga 31260

cgtaccgccg ttccccgtgt tggaatcgaa gaatatctga gataaacggt attgagactg 31320

acgaaacgta gctatagtac ctaagcgtcc agtagtatta ccaggagtat ttttggttcc 31380

ggcgccagct tgttgtaatt gaacacctct accccactgg tcatttccgt ccgcggtatt 31440

attgacatct aaatctgcca aggcttcgga agtaacacca gcctcaggtg ctctagagct 31500

gatcaagttt ataactgtgt ccctacgagt cagaacattg ggctcatcaa cgtttgcggc 31560

ggtttgcttt aggttaccat cagatcgcat ttgtatttct gtagtagtag cactatcccc 31620

gttgggccta aaagctaaga accccgtagt ctgtccgcta ccattgttcc ctgaaataac 31680

cattgtgccg gtatcattag ctcgtatcct ggcgccaccc tgccatgaaa gaatatggtt 31740

cttagttgct gtgagaggga agactagatt accgttcgga gcaatttcta ctgaggccac 31800

agtatcttca gtacctgcag gacgtaggta aatagatctg ttattcagtg aaattattcc 31860

tccagtaggc cttgctgtaa gcgtaagata ctcacttcca gaatcaccgg ttactcgtaa 31920

agccttgagt ttagccaggc taatgccatc atcaatcacc tgcgccctat ttacatagat 31980

aacatcagta tcaaaacctg tagttctcca cgcaggggct gttccgtcca ctaaaggtcc 32040

agtaggtgga gtaacagata tggaaccaga taaaaatgcc atcttagggt ctctgaaact 32100

actacgagat ttgaggtata catcgtaagt tacgttgcta ccctctatag tggacttaag 32160

ccccaccata aatccattcg tgttggccgg acctattact cgatgactaa ggaagctgcc 32220

gatgttatcc gcagttacag aggttacagg accaggtagc gccagggata ctatctccat 32280

attgtatatg tcatccctgt tggctccatt acctgtagcg tagagcgcaa acaatacgtg 32340

aacgctggaa gactgatttg cggctattgt tatggacgca atcttagctt ctgccgagcc 32400

ggtcatcact cctagtggtg ttaccaggga cgttttacct gccaaattct gagctacctg 32460

ggcggatgct gccgcattag tttctgaagt cttagctgct gtctgggaat ttttactagc 32520

ggtttcagaa gccttagcat tggtttccga agttttagca gcagcggcgg atgctgccga 32580

tttagtagca gcatctagta attctgtagc agccagggaa ctaactgagt agcctagctg 32640

tacggtaaat tttgggtatt tacttaccct tgagttagct ccgtcaaggg cagtaacctg 32700

ttgtgcaata attcttgttg taatagccat tacgcggtta ctccgtcact gacgtacacg 32760

ctcccttcca taactctata agaggtagcg gtagctcctg ttcctctggt catgattaca 32820

tcatagtaac ctgcgaaccg aagtctagga ttatatttat ctcgttcttt acttgctttg 32880

ttaacgattg ttgtcacagt agccgctgtc aatcctagcg acgcctgacc ttgtgtagca 32940

tttactactg ttacgacgaa atctgctaat tttaccccag tggattccaa agagtcttta 33000

attgaagact taagggttac ccctgtcaga ttgacagggg tttccgttgc tgggtaagca 33060

gagtcatcga tatccatgaa ctgtagcatc agtccgtatg atacattttg atcaaggata 33120

atatcaacta ctctgttttc cgtgctcatt tgttacctta tatgaatgta cccgttagcc 33180

aggtctattt tcattgtgta cgtaccttcc gggttagaac tcagtgcggc agccctattg 33240

tataggatgt caacaccaat ttgcgccagg aacgcgttat ttgcaataat cttatccgca 33300

gtgatagagc cagaaacgat catatcaccg tgaacagtta gtgcaggagc tgtccatgct 33360

gagccattcc attgacgagt ccaggagttc tggggggaac ctgacttata ctgagtcagt 33420

acatcatact taactggcgg tccagcgaag gttgactgga agaacgatgc tgcttgagtg 33480

tcattccatg cagtcaggtt tgatatcggc tgggtgtaga accccggccc acgatcccct 33540

acggcgtcat actggttacg gacatatgac gttacgaagg ctcccttttc aatcttacac 33600

cttcctacaa cgttatttcc ctcagattgg ttaactgaga atctaacgga tatcctatct 33660

gaattagccg gcgtagtgaa ggtaaagctg ctcaaacctg cagtagtaga cgcaatagtc 33720

ttcagcactc ctccagtggt attgcttccc ttagcgtacc agaatacgtg acaacgaact 33780

tctacagcgt tatcagtctc gaaagacatc gtatatgtgg tgtttggagg aaggtaggtg 33840

aacatggagg cgggtccatc tgatgggagg gtatacgcat cggtaactcc tgtacctgca 33900

attatcctag cccttagtaa ctcatagttc ttacctatag atgagccatt accagcaact 33960

ccggtaattg agtctaacca agctttaaag tagaacaggt tctcgttaat actatccccg 34020

tctaggcgaa taggatctga ccaattacct ataatagcat tagtttctcc gttaaactcg 34080

gccttaacca tccatagagg gctacctgga ggagggctat ctgaccagcc agccggatta 34140

ctaccagaag gcctactagg agtgctagcc attacggcga acttcatact cacatagtta 34200

cctttagaac ctggcgtacc attagcccca ttctccccta ctgctctgat cgctgggccc 34260

caggatccgt tcacctgttg gcgcatatac agatcacctg aagtaaacgt actgtgccag 34320

ttagtagaac cgtccttaga ccactggacg tttacagaat taccagcagg accttgtgga 34380

ccttgaggac cggtatcccc tttgttaccc tgaggacctg tagcaccagt gttaccttga 34440

ggaccttgag gaccagtagc tccatctgcc ccatccatag acagatcttc aatagctata 34500

gctgctacat aagcgttacc aaaaggtgag gcactaccat tcatctggat aaatggtctt 34560

gccctaccgg tctcggttga ccctccatcc gttaccgtta caataccgct tactagcttc 34620

catccgtcag gatctttagc tggcgcagca aacgcagtag gccacgcagt attgacactg 34680

ccattcgcgt tctgacaatg taaaccaagg cgtagctgat actcaccctc agagttgttc 34740

acccatgcag taatgcggta gcgcattcct ttgcgagtag ggaaccagtt attagcctcc 34800

atagtgtccc tagaagcaca cactatagct ttagtatgtc cccccggttg tccgttggca 34860

atatccacca catcacgacc ccacgaccct ctgttacccg agtcaaagga ccccgtgaac 34920

actctgtcgt aaccaatccc aggcaggctc ttcttgagcg taaacctctt aataagtgtt 34980

ccatacttag gatgtgtagc tttatagtcc acccacccag aggtaatttc catcccgtta 35040

ggcatattgc taggagcata ataaccgctt gaacctatgt tgccgttaag attgctctta 35100

tcctccaccc caaaggtaca ctggctagta acgtctactg ttccatagaa cactttgaag 35160

ttaccagtgg tgccgtccca gttctgcaca aaaccgtagg agttacagga caagttcgcc 35220

gcttcgttag ttaggtatcc gactagggag tttatcccgt cttgaagtct aactattgta 35280

atagaatcag atattccgtc acacgttgcg gttactgtta cgtactccga gctcccaaac 35340

tgagcagaag ttatagtctt gttagtggcg gtgccaccta aagttatatt accccccgcc 35400

tggttcttag cagtccaggt tattgcagca gtggtattct gtctccagct atctatctta 35460

atagtaccgt tagacttcaa gttaccacta gtatcgaagc taaatgacag gctatcggat 35520

gttagagcaa aggctttagc attactaccg ttagcccctt gtggcccttg tggtccagta 35580

gcccctgtgt cccctttgtc ccctttgtta ccctgaggac cttgtggacc ttgtgaacca 35640

tcggcaccaa tagtatccag ttcatttcta atgaacgctg tagcgaagtc tccctcttcc 35700

agcttgatat tggaaacaac gttggttcca cctgggttgt tgttcagtga cacacggaca 35760

gataccctat cacatcctgc aggaacagtg aacgaccagc tagttctgcc agcagttgtt 35820

gacgctatcc aagagaatga tgaggtagta gtatttgctc ctgcctggat aaagaacacg 35880

tgcattctca tctccagagc actatccgtg tcgaacgaca tagtgtagcg cttacctgcg 35940

gtaactttag tgaagaacgt accatcacca ccactaggca tggtatatgc gtcagttgca 36000

ccagaacctg cagtaatgcg taagcgtagt tcgtcagggt ttttagctac aacagatcca 36060

ctaccactgg cacccgttat agacgcaatc catgctttgt tagcaaacaa gttgaggttg 36120

accgtctcac cgtccagacg aactggatct gaccaggttc cctgaagttg gttgctggag 36180

tcaaactcac ctttaaccat ccagagtgga gaaccttctg gaggcgaatc agaccagtta 36240

gccggagagt tcccggtagg tctagcaggt ttagttgcag ctacttggaa tctcagggag 36300

gtatatttac catcagcacc aacccgccca tcctcgccaa ctgcgcggat tgcagaagac 36360

cacacaccgt taacttgctg acgcatataa atgtcgccag tagtatagtt tgtgtgccaa 36420

tcgctcgcgt tgccggtttt agaccactga actcctactg aagcacctgc tggaccttgt 36480

ggtccctgtg gacccgtatc ccctttgtta ccttgcggac ctgtagcacc agtgttacct 36540

tgtggacctt gcggtcctgt agctccatcc gccccgtcca tggataggtc ttcgaagtgt 36600

atgccagcaa caagcatata ccctaatgaa gcgcccgagg ttttgttatc taactggaac 36660

cacggccatg caataccttc gtcattaaca cttagggtca actcttgatc gaagtatgcc 36720

caggaactat ttgatgctgg tccggtaagc acggttcttg aaggatatcc tctattacca 36780

tccttacgat gaacgataaa ccctactcta aagtgggctt cctccagtcc tattgggttg 36840

taccagaatc tgatacggac tttttgccca cctactactg gaatagtatt tctaccttct 36900

aggttatctc tagctgtgat gcgtaacgct ttagagatac cctggttggt tggaccggaa 36960

acaccctgta gagttcctgc ccacgagcct ttgttaccat tctcgaaggt attggtgata 37020

accatctcgt agctcttggc caagaatacc ttagttaccg caaaacgctt ggtaattgcc 37080

ccgtatttag gatgagtagc cttaacatcc acccaacctt cggtaacatc agttccgtcc 37140

gacataccag taacagagta gttcccattt gaagagttga tgctaggagt tacgttactt 37200

cttccacctt cagagaaagt gcactgacca gtaacatcgg tgcttccgta ccaaactctc 37260

atctgacctt tggcgttttc gtagctctgg caatatccgg agtagttagc aagtaccgta 37320

gctgcctcat tcgtcataac agcagttaat acgttctcac cgtcctgcaa acgaaccaca 37380

gtaatctggt cagataaacc atcgcaggtt gctgttactg taacccactt agaagtgccg 37440

aagttcgcag cggttagctg acggttatct ccggagttca tcagtgttac tgcagctccc 37500

ttatcgttta cagcactcca cgtgatccct gcagtggtat tctgttttaa tcccttgaac 37560

agaacagtag cggcagactt aatatccccc acagtgtcgt atacgaatga ctggtagtct 37620

gacgttaggg cgaagccttt agcattctct cccgcgttac ctttcggacc ttgtggacct 37680

tgtggacccg tagcaccagt atcccctttg ttaccctgtg gaccctggga gcctgtagca 37740

ccagtgtttc cttggggacc ttgcggacca gtagcaccgg tagccccatc cttccctcta 37800

gcgtcaaact cattaagaat ccacgcagta gggaaagcgc ctaactccac cttagcccga 37860

cttatgacgt tggttccgcc tgccgcattt acagagaatc tcagcgagat atagtctgta 37920

ttagcccctg tggtaatagt tagggagtgt ctccctgcct tgttagtctc caggtaatta 37980

tttctaacaa aggagttacc atctccatta tcaaactgaa gtacaaacaa ccgagcttta 38040

gtagcttcgt ccacttccca ggaaatcgta tacatagtgc tcttctgaac aggtatgaag 38100

tacgttccag ggccaaagta cggttgagta tacgcatcag tttcggcagc cccagcagtc 38160

actctgaatc ttagctgatc gtagttttta ctaatcgagg aaccgtttcc tttcgcactc 38220

tggatagagg ccatccactc tttaagtgac cagaagttct cacctacccc ggaggcatcg 38280

attcgtacag ggtcagacca agtaccaatg atagcgttag tatccccgtt aaacgttgct 38340

gttgccatcc aaagaggaga accgtcaggt ggagcatcaa accaatccgt aggtttatta 38400

cctgtaggtt tagcaggttt agtatccgaa atacggaaga tgatattggt gtagttacct 38460

ttcttaccat caggtccaat ttcacctttc tcaccgatag cacgaatcgc aggaccccaa 38520

acaccatcaa cgttctgacg catgaacagg tcgccggttt ggaagttatc gtgccagtta 38580

ctagcagagc tatccttaga ccactgaact agaactgatt tacctaccag gccgatacta 38640

tctgagtatt ctacctgata atcagtcttc tccccaccct cttccagttt gattttactc 38700

cacgtggttt ctacgttgag agtaagaatc gaagggcgta gggttaagta gttaatacct 38760

gccggaacta caaaagtgcg cttaacctta atcgatgttc cggtgttaag ttcttctatg 38820

aacgtggact gcggtgagtt cggagcagcc tgccagaaaa taatatctct ggtttggact 38880

tcgctcgccg catcaatatt gtaggttaga gtgtaacgct tacccggagt taccggatga 38940

gagaaggcac ttgcaccaac aaaaggagtc gcataacatc caggggatgc gttattagtt 39000

ccagaagtac gggtcagaga atgagttagc ttctcaatgt cgttctttga tgtaccagag 39060

tccgtaccag tcagcaatgc catccatttg cgaactgcga acaagttagg gttgatagta 39120

ccatccagac gaattgggtt agaccatgtg ccttgcagct gaccactagc gttcatcgta 39180

cctttagtca tccatagagg actaccaaca ggaggagcat cactccagct acctggactg 39240

ttaccagtag gtgtgccagg tttagtatct tgaacgataa acttcattga aatgtagtca 39300

ccgtcagtac catcttcgcc aactgcacga atagcaccgc cccaaactcc attaacctgc 39360

tgacgcatga aaatgtctcc agtttggaaa ccagcatgcc agttagtaga cccgtcctta 39420

gaccattgaa cgtttacaga gttaccagcc ggtccttgag caccagttgc accagtatca 39480

cccttgtccc ctttactacc ctgtggcccc tgcggacctg tagcaccagt attaccctga 39540

ggaccctgag cacctgttgc accatcggcc ccgtccattt ctagggcgaa catatgaata 39600

tccgtgatga aggcttcacc aaagttggta ttagtggcga tctgaataaa tggtctggct 39660

aaaccagtat gatttattac tactacagct tctgtgtagc cccacccagg ctcccctttc 39720

ctacggagga gtgcggtagg atagtccata gctccagtat cgctacgctt catgtggacg 39780

ccgatacgaa gatcagcacc aacgtttact gtattcgccc acccagcaat tttgaacttc 39840

tgacctttaa ctactggaaa gtagttagcc tcctccagag tatcgcggtt agaaactcta 39900

agtgccttag aaaacccagc agagataacc tcaacatcag tagaagcaat atctacgagc 39960

tgacctccag caccccacga gcctttactt ccattctcga aagaggtagt gatgatgcga 40020

tcataacctt ttgcaaggat agatttagta gttgccactc tgcgaaccac agcaccgtaa 40080

gtagggtgta ctgcacgtaa gtcaacccag ccgttgataa catcagtacc agccggcatg 40140

ccttttaagg tgtacttacc agcagcgttg atatccgcat cgaggttgtt cttctccata 40200

gtactgaagg tacattctgc agtgatctcc cgcgccccgt agaacacttt aaaatcacca 40260

gaaccagtac tgtagttttg gacataacca gcatagttcg aaagaacggt ggaaccctca 40320

ttagtcagga gccctactag agcattggaa ccgtcatcca gacgaacaat agtgatctga 40380

tccgtgattc catcacaaac ggctgtgact actacagact tcgatgtttt gaagttggca 40440

gcagtaaggg aagcccccga gttgctaaca ctagtcaggg taatattccc ccctttctcg 40500

tctctagcac tccatgttat gttagccgta gtgttctggc ggaaagcctg gaacaagata 40560

gttgcttcag atttcagctt accttctgca tcataggtga atgtctggcc tagagaggag 40620

atgctgaacc cttttgcatt atctcccttg gcaccttgtg ggccttggtt cccttgaacc 40680

ccctgtgggc cttgagcacc agttgcacca gtagcaccag ttgcgccctc ttcaccgata 40740

gtatcgaact cattacggat gaaggcggta gggaatactc cctcttcaag ttttaactta 40800

ccaatggtgt tctctttacc ggcttcgttc acagagaatc gtaatgagac tctgtctact 40860

cccgcaggga ctgcaaaagt atgagtagta aggcctggag taagcgaaga cgtattagtg 40920

aaaatactcg aagagttagc ccctgctttg attaaaaaca ggtgagtcct aacctctaca 40980

gcagtgtctg tctcaaagga gaaagtgtac tttttaccag tagtaactgg tatgaagtac 41040

gttccatttc cacctgaagg cacggtatac gcatcattgg tggaccctgc aacgattttt 41100

aacctcaaat cggtagggtt cttaacgata gaagccccgt taccattagt acctgtcaaa 41160

gatgctaacc actttttagt agacagtaag ttttgattaa ccgtatcacc atctatacga 41220

accggctctg accatgtacc tactagggca ttagtttgac cgttgaactc ggctttagcc 41280

atccataggg ggctaccctg cggaggtgcg tctgaccaac ctgaaggagt ctgacctgta 41340

ggagtagcag gtttctcatc agccacgcgg aatcgcagtc caatgtagtt acctttagac 41400

cccggagtac cattagtacc atcttccccg actgcacgga tcgctgaact ccagccaccg 41460

gtaccaacac gctgacgcat gaagatatca ccagtagtaa agtttgcatg ccagttagta 41520

gtaccatctt tagaccactg tacttctact gaaccacctg ccggaccttg aggaccttga 41580

ggaccagtag caccagtagc accagtagcc cctttctcgc cgtctactct gatcgggtct 41640

gaccaaccct caacagttag agcgttagta tcgccattga atctaccaga acacatccaa 41700

agaggggttc cagtcggtgg ggtacgactc caaccactag ggtcattgat attgcctggt 41760

ttcgtgggct tactagcact gatctggtaa atctgaacag tgtaatcacc gttagaacca 41820

tcagtaccac cagtacctgg gacaccagac cactgggatg cagctgagta gttggtaccg 41880

tctactagag caggaggact cttcttagga tccagagtac cctgcacaac gtacacgttc 41940

tgattctgag cagtgcggtt aggcgggaat gcggaccatc cagctggtgg ataaacttgg 42000

tcaagcgggc gacttggcag agatgtacca agtttataag caaatatagt ctgcttaccc 42060

tgcataccgg tttcaaggtc tacatcgcct ccaggagtac cgattacaac gttaccagaa 42120

atgcgaagag tatcaccgtc ccagcgcaca tactgagtgt tattaccgag gtcaaatttg 42180

gccttaccgt caacgttgtc aacacccatc cagacaccac ctgcgttatt accgtacttc 42240

ttaccctgag tgaagattgc cgggttatct ttaccggtca ggttagtaag aattacgtta 42300

gcagcattaa tatctttagt gataacttta ccatcgacgt ttacaatctt attaacaggg 42360

tcgaatgaaa tcggcgcttt accattttca tcgagtgtac caagaactac tgcacctgta 42420

gcagcatcga ctaagaaagt ctgctcccac tgtttggtgt tagagttcca aagtttaccc 42480

ttgatacctg cgtaggtcat ctctacaccg gtctcgttaa tgaatgcatt gtcgaaagtg 42540

gtgctctcgt ctataatata agtaacctcg ttagagttag ttatagactg agtatctggg 42600

ccccaagcaa ccgatagtac acggaagcgg tggcggattt tgtaagggaa gctagtgata 42660

gtaccagctt tagctgcacc cacgtttagc ttgttggcct tagtccatcc agtttttgca 42720

aactcatcgt tactaatata ctggatgata aattcacgaa cgttagcacc tgtaccacga 42780

gtccaatccc attccaggcg aacgtcaaaa cgctccatac catcttggat gtgggcggtt 42840

ttgaaacgca ggttagttgg ggcagacggt ggagtgaagt tgtaggtcag gttaaacagt 42900

gatggccagg tatcataccc agaaacatcc acagtaacac cgtctggcat agtgacaaca 42960

ccagataccc ggatattgta tctgccaact ggaacaccac caaagatgat ctgctcagtg 43020

attggaccac ggtagtactt agtccaggtg ctagagccct caggtttcat ttcgatggta 43080

acgtattcgg cctcaccaga aagctctacg acaaccatag gagcacccac acccacgtca 43140

acagattctg caaaagagga cactttggta atcttcggag cagttttcat cttgaagtta 43200

acggtgctag agaggttcat acctacttta gcagccatca gctctgcatc aaccatcgag 43260

tcatagaaag caccctgggc agagtaggta gcgccagcga ttagattgtt aattgtggca 43320

atgaatgtat caacgccggt aaagtcccta cgggtggtta ccccacccgt agttagccag 43380

aaagttctac caattacgtc gtaatcggaa aagattgagt gctgaatact cgcaatcgta 43440

tagccggtca cgatattctg cagtaccatt ttagctggtg ctatgtttga aatcatttag 43500

atatatgccc atgcaaccga cttctcgccc tttggtccct ccgcctgaat tcttggctga 43560

agtgctctgt aaatccccaa agtattcgag ttgttggcct tgtagtcgag cttattgtag 43620

cccaacaggt agctatagtt atataaactg gtgatcttcg cggatctaag cagtttatta 43680

gtgttgtccc ttatttcaag cgtgtagaaa atccctgaaa tcagcccctc ttcttgcagc 43740

ttatcccatc ctaactctaa gtcaggtcct acccattcag cagggtcagg agcaaggtta 43800

agcacccgga agttttccac catactaagg ttcttagctg agttcaaatc tacagaaatt 43860

gttactggag agctacgacg accgttaata tcaacggcgc ggatctcgaa aatagtcagg 43920

ccagcaggct cacccacgat atcttggaac attctaacgt taggtgtgaa agcagtctgc 43980

tgcacaatat aaggatccac acggtccgat ttacgtattg agtaatagac tacgttaggt 44040

gtcaagctag gaagccatga aagctctccg tttttgccaa catcacctac cattccacca 44100

ggtgtggggg tgtacttaaa gtctcttgga ggcaggacgt tattggatat ttcaggaacg 44160

gcctcgctac tgttatccac ctgcgttgag ttaataaata catcctcacc atactcctga 44220

agagttacgt ttatcttacc atcccttgtg ttctccacct catctactag gaagaacttc 44280

ttattccagc cataacgatc gtaggtgaat actacaggat cgttaggttc tataccaagg 44340

aatttgtaag gtaaagagaa actcagagag cgagagtaac gagacttctt aagctctcta 44400

tctgccaagc ttctagcagt gtagtagttg gttatgttag caaaagaaag ttgaagtttc 44460

ttgtcaactc cacgatcttc attcttaaac ttagaattat agaacgttat agagttggtt 44520

ttccagttca gggtaggatc aatcagagat acctgaactg agttgtactt attacggcct 44580

gtagtatctg agagatccag gtccccataa gtatctagga aattaagttc tagcggagtt 44640

tttgaatctt tctctacggt gatgcggaag atacctgata ggttatttaa cgccccctgg 44700

aaggattcta atagctcctg cacgtttttg aacacagagt tggagttatc caggattgtg 44760

ttcatttgca ttatttgtct gttttcggct gtccagctct cccatccaac gtatctccag 44820

aaaggttgcc aactagtttg ataagaggtg tcgataatgt ttaatagatc agcctctttt 44880

ctccagtcac caatcaccat tctgtctatc gggatacttg caccaaaggt agtggaggtt 44940

aggtagtcaa atgtttgcca cacaccattc tgactcgttt tatccatttt aacagaacca 45000

tctgcccggt atactttcac tttgcgtccg cttaattctg cggatacttc aggaatatca 45060

gttctgttct ccgtgatagt gaaacgtatg acagcgtatg cggtgtctaa taacttgtat 45120

ctagaatccc agtactccgg accattaccg ttctctcctt gaaggaagaa gttgttagca 45180

gcagcaatgt ctcttagtac cgtagctacc gtttggtctg gcttgccatg gaatgtccag 45240

attcgtatat ctccattacc gtcattatac ttgtattctt gaccatgcgt ggagagagat 45300

gttgatggga gtcctgtgga aattcttgcc atagtatctc ccgacaccct tttttgtcca 45360

aagcatgtac gagaggtact gtcagtttga tcagtacaga tcataggggc gtccccaaac 45420

tggaagtcta ggaatccttc aatctcaccc tcacagaacg cgtaaactac atacacaacg 45480

ttcggattgt ttctttctgt atccgcgaaa accggaatac caggaacttt ttgagtacca 45540

tatactacag gaataaactt ggccgcaagg ttgaagtcca ggtctacttc tttagtaaca 45600

gtctcgtaat actttttaag gctgtagctc ttggagagac cgaataattt cttcttagat 45660

tctagcttgt atcgttcttc ttttacttga tatttagcta ggaagttaac gctcttgttg 45720

gcgtggaaga atccgtagtc ctcttgatat tccggtcgtt tggcaccgtg agaaggtagt 45780

aattctccat ttacaatctc aagtcctcgg tgggaagcgt cgtctgtgaa gcgtccagca 45840

actcgctcaa aatcgtagaa ttcgttagaa cagttccaag ttataacaga agtaccaact 45900

ccggatactg tattactttc tttaatacca ccacccacaa tcttacccct aaagaagagt 45960

aatgggccgt tagtatctgg gtccactgga aggatttccc cattgtcgtc gatgatcgcc 46020

tgatatatag aaatagagcg atctaaaaat gatacaccac tttgcacgag cttaatgact 46080

tcgttggcat ccgtaccagt aacactgaag ctcaaactgc cgacggttaa cgtacggttt 46140

tgtttgtgac tgctaattgt tttaattttc cctgattgga agagtatacc accatagttg 46200

atatctctca tatagtccgt catataagca taaacagcat tattacccgt ggaccccggg 46260

agttcgatag agacaagata cgctaatcgt atcttgtcat tgttggcaag gtaggctttc 46320

gcagaaggaa ggatctgtct catagacttt ctctcagaac taggttaacc ccgtcatata 46380

caccatcaac tgtgatctct tcgctgaatg aatctccgtt cattaattta gtttggaaaa 46440

gaatcccatt gaaacgtggt ctctcggagc cgttggtagt gagcaacaga tcagggtata 46500

gattaagtgt ccatactcct gctacgtttt taaaagatgt aatcttatac acctttggat 46560

gtgtggttaa ctggaataaa tcaccgggct taggctctcc agatagggag ttcgtattgg 46620

tgataaccag tgtggagcct ttttgtccgg cggcaatgcg acagttgttc gcatcccctc 46680

ttactcggta agactcgtaa tgcgggagta taacgtcgag atagcctctg gtacgcttat 46740

actctagaat tgctgacgaa agtacagcat actcatcggg aaacatcata ggataactaa 46800

tgttaagacc ccaatactga gtggctgttt taacttcgtt aaccttgccg tttggtagct 46860

catctctgat catcggatcg ttatcgatca gcgtagctct gtcaaaccca aggccgttat 46920

actgaggatg tgtaaaggga tctggtaatc tcatgttttg ttttctcctc tcaatgttaa 46980

tattatagtc atatcaagaa aaattttcaa gataatttta taaattccaa aaagaaggga 47040

ggacaattac gtcctccctt tagtttagtt aattcaggtt ctttaagctc agcccttgtt 47100

cattcaaggc taactctaca gctgcctgga atgccgcagg gttttccaat gcgtactcca 47160

taaagctctt agcatccatt gcctggatat tcagatgaac cggtcttcca gcaccgccag 47220

aagaagtttc agaagctact ttatccgctg gagttacttt ggtaggcacc ataggagttg 47280

caacttccgt accatgttca cccatcttat aggagacacc tggataggta ttaccaccct 47340

ccgcacgagg aataaatccg ttagcactac ctataccttt atcacctcga acgtaagaca 47400

gctcacctgc gtttgcgccc atactaacgt ctacgttctt ctggcgctca cctaaggtca 47460

ggtaagaggc agtttcacct ccagaccctg ctatatcggt cattccagta gcactagacg 47520

cctgtgctag agatagagca cctgcaagtc cagccgcgat cataagagga atagagaacg 47580

gatacgggac agctgttgct gcctgcatta ccgctactgc tgtctggatg atgatttgct 47640

tcttggcaga ttcctgctga agtttaatct tctccgcttc catcttcttg atcttgttct 47700

tagactgctc agatttaccg tcacgcttct gctccgccgc gatagctgca tcaatagctg 47760

aaatctgctg gttagtaccg aagctgatca tctggctaac tgtctgcata cctaccgcaa 47820

ccatagatgt agtatctaga gatttctgag agaactgaat catggcgttg gctagattac 47880

ccatactttg agcagtagca gtagcttcag agtttaattc acttagtttg gagatagctg 47940

tgtcataaga cgccatttgg tttcccatat ctgcaaattt cttatcatct ccggctaatc 48000

ccgtagttgg ggtatagtct gcgcccaacg actgtcctac acctgcctgc atctgagcat 48060

tacgttgagc tgctaatgcc gccatttgcg cattagtttt tgctatctcg gcgttccatc 48120

gcatctgttc atcagcatta cctttagtaa actctttcat ttgtttgtag aattctagct 48180

gcaattccat cttttgcatc tcccctgcta gtgggtacag gctagttagg gtattctcaa 48240

atgcctcttt acgcatctca gcagtttttg cattacggtc aagctgctct ttccagattt 48300

ccctttcaat tgaagcgatg ttacgtctag actgctcggc ttccttctct ttgtcagcct 48360

gagtcttcag cagagctaac ctatctttct ctacttccag atttagttta aggttcgcca 48420

cgttatactg ggaatctgtc atagtacggt tagagagtag agctatctcc ctgtcaatac 48480

caactatctt atccttgtag aacttctcct tcttagtaga ttccatgccc tggtttttaa 48540

tcttgaactc ttcagtttca agaatagtta gttccttttg tagggctttg ttatccttat 48600

tcgtagccag tactgcctgc agagcagctt tcttggactg gagctgttgt agctctagtg 48660

ctctaccagc ttcttccgcc ttatccttat tacgagtaga tgcgtaaaca tctgctatac 48720

gtttttccac ttccagctta gatttggctt catcccctgc aatcttatgg tagttagtca 48780

tagccttata agcagtgttc atctccgtta cagaagagta cccaagattc agatccttag 48840

ttaactggtt agctttttca gtagagcccc cagccagggc ttccactgct ttaagagcat 48900

cccctagagc tgcggtagcc ttagccgccg tattagaatc ctgtgcgaag ttttggatat 48960

cattacccaa gtctccagca gttttcttaa tattgttgta ctctttgttt atggcaactg 49020

ccccacctag agcatccttg ttgaaggtgt aaatcccgtc acttgcttcg acgttctgcg 49080

atatattaag ctgattggct aggctagggt ttcccttctg agttttagcg agtgcattgt 49140

ctctagcgtc tctccatttc tggatggctc cagatgagtc ctccaattcc tgttgcaact 49200

tatacgcttc acgacgcata tccgcagttt cttgagtgaa cctcttgtta gcctcagaag 49260

ctcctaaagt gaaagagttt cctagaccct ggtagttggc attcacagca agtttagtag 49320

ccatatccat cttagattcg cgctctagga tatccttgtt aagagctgca agtctcttgc 49380

tggcctcttc cttggctttt atagcgtctt ctaatccttt ctgagatgct tcaaggttca 49440

ttaccacggc gttgttatct ttaacatcca tcttacctat cgattcctgc tgagcttctg 49500

ccgctgctga ggaaatggag gctttagagg agtaaaacgc tgcgtttata gatgcaatga 49560

caggtccaag atacttagcc gctgcctgct gaaccttacg tagtgcagag tccgcattcg 49620

cagcaaactg ttcccaagga gtagcacgaa gtgcatcatc aagatatccg aaacgcttag 49680

tagattctgc tacaactgcg tttgcatacg cttgctgttt ctggaatgag gatagactct 49740

gtatgttata agtcataccc gtgttagctg cgtttagttg tttaacatgt tcggcgaatg 49800

catcattcag acggatggtt acacccagtt cgtccagaag ttcgatttcc tgcttagaca 49860

cacccttaat tacacggttg agtgcatctg tcatgtcaac acctagagtg gctgcggctc 49920

tacgtgcaac tagagcaaac tcaccaatct gtttagaatc gaaaccatat gcggccgcag 49980

tagacgcctg gcgcatagcc tcctcgaagg atacggcata accagtagct tcctgcagtg 50040

cgattgctag cgattgaatt ggtgtacctg tcttagcacc tacaatagaa ccgaactgct 50100

caagacggtt tagctgatcc cccatcttta attgatcaaa agctgctttc agtacgtaga 50160

ggttggatgc caatgcacca tataaaagcg gcataggtcc agttaccata gctagagctg 50220

cgaagtttct tgtagcacca cgagcggacc ctgaggtatt acccagcgcc cttgatgctc 50280

ttcctgcggc gcctccagta cctgttaacg ttgagttcag cccgcctaaa ccagtattaa 50340

catcacgaac acccgcgttt agatctgtta atttgtcaga taccttgtcc gtactccgtg 50400

ccatatcagc catggtggta ttcattttgt tgcccatagc ttcaatggag gttacaatcc 50460

tgttcatttc cgccactaag gcacccatat tgaatgctgc agggttgccg cccccaccag 50520

cttgtcctag gcgtatacgt ttggctatta acttatctat cgcagcagca gaacgtatcg 50580

cagcagcttc aatagcgttg agctccggta ccactttctg gaagttatta atcattctcg 50640

tagacgacga ggttgattta gatgccatat cctgaaatcc cttggagaac ccgcgctcta 50700

gtatttgaga cgtggaggcc agtttagttt ccagagcatt taatgaggcc gttactgctt 50760

tgaattgggt aggtaattga agtacgcccc tgcctgcctg tatttttgac agagcggagt 50820

taacttgcac agcggcctta gccagctggg tgagtgacgg gatcatacct ctgatggagt 50880

tacccagtgg attcaggttt cccgtgcctc ccatagtggc aaaagctcta gatagatcat 50940

ttaggctttt ctcgataccg gttacagatc cttctaactg agcacgcaac tgcgtcattg 51000

aagtacctat ctttccaaca actgtaggta cagaagaaag atttgcgcct gctttaatgc 51060

tctgcagtgc ttttcctgct gccgtagcat ctacgttaag ctgttttaaa gcggctgtta 51120

ctttagagat atccgaagtg gaagctgagg tggctgttga tatctctgag attagcttgc 51180

tcagaccact tccggttcct acggttttca ttgaagcggc agctgtagcg gtagaggata 51240

ctaaagacgt aagggctgct ttaatcttag atatctcagc taccgaggta ttggctgcag 51300

tagctaaact agtattaatc ttctggattt cagttcccag actattcagt ttggtccctg 51360

gtgcaatatt tgctatagat ttactcgcta aatcagcttt tactgccaac tcaagaagta 51420

gtttgtttag cttgttcacc tcttcgccca tagaagatac agctacggaa atcccggacg 51480

cagccttact cagatgctct ccggcagccc ctaaggagtc ggctttcagc ccctgaagag 51540

acctgcctgc cagcacggct tgctccgcca ttctagctaa ttggttacct atcttttcca 51600

ccccagatac taggtggcta agatccgtac tagccttagc agcactagag ctaatagatt 51660

ctaacccggc ccctgccttc aaggtctgca acactttagc tactgaagag gcgtgtgcat 51720

ctaactcctg aagagcctta ttgacgcggt ttaagtctgc aactgaagaa gtagctgctg 51780

agtcaaaacc agaggccatc ttgttagcgg cggaagtcac cccgtttagg tttgcgttga 51840

tttttagtac ggatttagcc aagtcaacct cgaacgaggt aaacttgccg cttagcatgc 51900

cgatagatgc tgctaatgct gtaatgctgg tggtcgagga tagtttctcc agcgacttag 51960

cagtacgtga tacagatcgt tccagcgccg tgaaagaccc aggaagtttg cccaagcttg 52020

tatttagacc ctcggagctc tgagtagctc cgtctaaagc agcttcaaca tccctgattt 52080

gcttagcggc tttggatcca ccacgctgct tgatatctac aagtaattct cgtattagtc 52140

tatctgtcat gattttttcc aataaaaaag gcctagggca ttaaccctag gccaagcctc 52200

acgtggaacg cccgttggag gaaaatgtaa ctcactatct gctagaagac ttcattttag 52260

acttcttaat agctgcttca acacgtttgc gagaggctgc cacagcatgt gagtcgaata 52320

tgttgatgat ctggagtata agactcttct catctggatc ctcgactccg tagatatcga 52380

agaaaactag tagggcactt ttatccttgc ctaaataggt tggataatcc ccggggatat 52440

aattgtccga taagttgtta tatattgtta gagcggtctg tgcgatttca gggaagtcat 52500

ggatctctac gaaacgttta agtacctcgg ggttaggttc ctccccgagg gattcgcaca 52560

tcgtcagata ctgctcccgt gtaattttgg agtccccccc tttgacacat cgttctgcaa 52620

aggcatctat ttccttaagc agtaggttcc gattttgagc cacgaaaggt gtctaggtgg 52680

aagaccgtgc tattcatcca ggtctcaaag gcactggagt tacgcaccaa catcatcgcg 52740

ttgtcgatac taaattcgac cttatcttcc agacggtctt ctggaacttc gatcagcatt 52800

agcttctcaa catcagctac ggttagacct tcccagcctg caatagccac cttgacgaac 52860

tcttctgcga atttgtcgtc gttctgcact ttaacagcga taccattaac aaactggttc 52920

tcttgcgcgg cttccaggat tttcttggag agcttacggg agacgtagtt aactttcagt 52980

ttgaagtgtg gtaggccagg gtatgcaatg gtgatctgtt tggtatccag tgcaatatct 53040

tttaggttaa tactcatttg ttattctcca attagcttga ttcggacagg atctgattgt 53100

tcagtaggta ttacgtcata atcgatcttg tacacgtcgg ttaagtctag gcgttttgtg 53160

attcgagtgg aagggaaatc caccacaata tatttatttc tgatttgtac cggtaggcca 53220

atatcaggtt taatgttatg cgtagagtct atctgaagac tctttgcata gtacatcgat 53280

atcaaagcgg atgagttcaa ttcgttaacg attgcccttc tattattata aatcttattg 53340

atatcgaata aacttctgtc accccgccat tcacattgct gctggaatga cataccggct 53400

gacataagtc ctgggagcac tctcccattc gaagatacct gaggcaatga aaatggtagc 53460

acctcacctt ggtcaagcgt atagctgttg agtgggtggc ctacttcctc aaagtatccc 53520

gactcgatac caacgtttag caccgggaca ctcttatcta gagaaaagtc gcaggtggta 53580

gcaaaacagt tatcgaaacg taagctcgtg ttcttgttaa taatatatac ggagaacatt 53640

ttaggctcaa tattattact gaacaagggc atctgataca ttccgtctat ctctataaac 53700

cccatcaatt cgaaaaatag accttcgaga gcattgctag agaagttaag agttagagaa 53760

attgaagaag gagactgagc agttatcttc gaataggcgt agttactgcg tctgtgaatc 53820

gtcctacgat tcgctttaaa ctcttcgtag gacgttccag cagtgtaatc agacagggcg 53880

tcaaatccgt acgccctgcc atcgtactcg atgactactc tagactcccg cattagggag 53940

tatagcatta gttatcctta ttaaccgcct gaggcagcct taccgtcacc agtggagatc 54000

agcttagcaa ttgaagtttt agtatacttg gcagagaagc ccaggtaacc ttcatcacca 54060

gcatccatct gagatggaat agctttgaac tcgatagata cgcctagcac atcatcggtt 54120

tcgattgacg ggatattcag gttagcatgc ttagccacca gaacagctgc aggacgtgca 54180

gtatcgtact ccccgcctag gatgattgca acttcgaagt cattcacagc tttcagctcg 54240

gagaccagat ccttgtacaa ctgaatagag ccgttagcag catcattcat gtatgcagtc 54300

agagaaccag taagctcgaa ggagccagta aatgagccga tcggaacatc aacacgtgac 54360

atgatgttag gcgtcaggta cgttacgttg ttgttcatag tgaaggagcc accggtgatc 54420

gggatgttat aggtcttacc accaacagcg ttgttcttca gcttaaggat agtcagcttg 54480

ttcttgatat aagaaccttg aagtttagca tacagagcat cattaatccc aatggtgtta 54540

gggtcaaacg gctgtgcaga caaagtttcc agacgagtac cattacccga ccaggttaca 54600

cgaccaatgt cgtcgatatc cacgttaact tctgcctgcc caacctggca gttcttgatc 54660

acagaccaag cattgtcagt caggatgtag atatgcagca tggccagttc gtggtatgcg 54720

ttatccttga agttgacaac aaggttggta tcgttctgga agacaccagt agtgcccgct 54780

aggttcaggg tagcacctgt tgacaggccg tgccagagta ggtagtccgg gaggatctgt 54840

ttacctgcat cgtcatatgg caggatatag gtggagaagc tccactcggc agcgtttaac 54900

gaatcgttga agcgctggga tccacgagtc ggcttcggac cggcttcgtt taaagtaata 54960

tcagtggagt tactgtcctg accccaagag atgtcgtcct ggactaggat ctcctgagta 55020

ttggtcttag tgaaccccgt agtaacggtt gacacgaaga ttcgtgtatt acgtaatagt 55080

tgtacagaca tttaaatttc tcctgagctg taacttatct atccagcgct cttctcagag 55140

gcatataccg gactgttacg ttaacttgag caaaaccaaa cggggacagt ataccctcgt 55200

ctgtggacac cgacgtgatc tgcatgtcag tggcttcaga atcgatagtt gaaccatcag 55260

gtttcattat agtatattgt aaatttcctc cagtgtcaat agaggttttt acatccgcta 55320

tgagtttctc aagttgcatg ttaatatcat ccttttcttt atcatagata agaataggaa 55380

tttcaaggta aacccactgc tgtgcagacg gcaggtagtt tccagtttcg gtacccacat 55440

ggactgctat gtaagggaac tcattgatct gctcaaacga ataagtttgg cgggatacgt 55500

tcccatacat attagtgaag aactctgtgg gattactccc atccatgtcc ttcttcagtc 55560

gttccactag ggcatcagca atacttgttc tgtaattcat tatgtaccct gatttactct 55620

tatccggtat ctagaatgga taaggtctct tgcagcctta gcgattgcct cgccgatcag 55680

cttctgcggg ttcctagcgc cagggaaagg ccgtaaggaa agtccgcggt aggtagagac 55740

ggcaggattg aacacagaat aaggcttaag catatagtta tacgtgatgt tgagatcagg 55800

attctttgac cctgcgtctt ctcttaacag cacgtcttta attttcaagg agttagcgaa 55860

acgccccgtt ctaaatttaa ggggtgcccc agcttttttc atatccttga ctaagtattc 55920

ttttgctacg agttcaagta acgctctaag gtttgtgttt gagacgaaac gcccagaagc 55980

gccagaaata gcaccagcgt aaccgttgtc agcatctgaa gggtctccaa agttaacttc 56040

taccctaccg gtagatcgtt ttcttcctat tttggatttt ttaccagtga tactatttag 56100

aaggttatcg ataacaccaa cgtcaccttc caggttaagt gacgacgaga cagcttttaa 56160

aatagaggac gtccgaacat tcagtaaatc ctccgatacc ggcttggtaa atcggaagga 56220

taccttgcct atggtgccat ctttgtggtt atccatagtt tccgcactat ataccacggt 56280

gttcttggta gagtggctac caccactcat aatgtccagc tgttctttaa ctatctgtcg 56340

agctagatcg cccaacgcca ctacagcctc cgatatactt cgattatagt acggatgtgt 56400

tccggtacgc cagatttagt ggtattgaaa gtaacggttt ctccgccaaa tgtacgagac 56460

tcgcggtagt ccttcttgac ccaatgatca actaggaagc aggctgctag taccaagtca 56520

tcagggatag aggtaaagcc ggtctgagta aactctactt ccatataccc ctctggagga 56580

gagaatttca gcaagagcgt accatccggg tagttcttat attgcgactt atcgatctcc 56640

tgatcgttaa tcgtaatttt agtgatcgtg ctaggcacag gagaagacag gaagtacttt 56700

ttgcgtgctg gtttagtagg caaaacgtct acaacgctag cactgtcgtc aatacctaga 56760

agctgagtaa tcagagcatt agccgccttg attaacattg ggatatttga ctctaagtca 56820

ggacgtttaa ggcctccata tgttctccaa tcagaatctg tcatgaattg catattttac 56880

ccaataaaaa aggagagccg aagctctcct ttagtcggca gtatagccaa attaagcagc 56940

gtaagcacca gcaactacgc cgttctcgaa gaaacgcatc aggttcagac gctgagtaac 57000

gtagtacgca tcgcgctgac gttcagcctg acgctctttc tcaacagtga ttgcacgctg 57060

acgaggaacg atgaagttgt cacggtaaac aaccacacag aactcagcac ttgcagcctt 57120

agctgggaag aactcagaaa ccagtaccgg cagaccgtag atgcgaccaa cctgaccctg 57180

cagtttgata gcggtggtag cggtaacctg tgcaacgtcc tggaactctt catcttcgat 57240

cagatcgtaa taagcatcca tcgaaacaac cagagccagt ttgttcaggt ctagaccgtg 57300

gcggcccagc gaacgacgca gcttgtgaat ttctttagcg gtaactttaa cagaaccgtc 57360

agctttagca gtggtagcaa ccactttacc atcgtcttta gcgaactgga tcagaccttt 57420

cggagtacca gcagcaccag taccggtcag gaacgctttc tcgattgcga tagcgtgagc 57480

ttcaatcaga cgacgacgca tgatcggcag cagagtgaag atagcatctt cttctgtttc 57540

gtcggtcata tacgctttag cagccagttt gtaagtcttg aaggtgattt cagacagctt 57600

ggttttgtct tccgcaccaa cagtagcagg agtaccgtag gtagaggcgt caacccagct 57660

agcttcacca gcttccggct caaccatcat ggtcagcaat ttgctagaca tcggcagttc 57720

ttcgaacatg gtaccgataa tcagtttagc ctgaatgtca cgcaggatac gcagggagaa 57780

gatggtttcg tacgcttcgg tagaaacttc gatagaagaa gagccgttaa cagctttcag 57840

gtgggcttcg ccacgcttag taccgaatac atctttctgc attacgtagg acagaagaac 57900

cagtttctca acttcgtctt cgaaatcttc ctgcttacca aacattgctt tagcaacgcc 57960

atcagctacg aaagagcgac tattttcacg tgcggccagc agagatttga tttcttcctt 58020

cagaccggtg atttcttcct gctgtgcttc tacagcttta gcgaatacgc cagcggattc 58080

tttggacttc tcgtccatcg ctttaatcag ttctagagct ttgctcagat cttcctgagt 58140

tttaccagag gctttagcga ccaggtcttc catacgcttc agctctgcgg cttctttctc 58200

ggcagccatt ttacgggctt cttcagcttt ctgcgcagca gtaaggcctt tcagagaatc 58260

agccagttcg gtcaggccca gttcctgttt cagtttgtca atatcaagag gtgcagacat 58320

ttaaaatttc tccattatgc cttaatgcag cccagggccg cggcaagttt ttctatttca 58380

gaaagttgtt tttcttctaa agcaggctgg gcctgtgaag atttaatgaa agtcttacga 58440

atttccatgt aatcattatg gtttacagac ttcgaaaggc taaaagttga gtcttggttg 58500

cagggaaccg agactacaga gatctcgagt aactccagat ctttaataat gaacgtttca 58560

gtcatatcgt cccattcggc gtctttaata tagaagccta ccgagaacgt tttaagaacc 58620

tcatcacgta ttaatgagta aatctgtaga tcagcagcac ttacctcacc ctcaaccata 58680

agtccggact cggttggtac caggtctagg atcttaccaa ttgggcggct atggttatgg 58740

ccgaaaagca tgatcgggtt cttcataaaa ttcttgaggg cgttactggt agtccacgct 58800

tcggagagaa taacgtcgcc ggcgcggtct ttggtaatcg tgttagcata ccctttgatt 58860

tttaaaggag gattatcacc ctcaccgaca gctttaacag atttaatctc agcattaaga 58920

ttaatattct gcatcgtttg ctccaaacac tttcgtgttg ttcctcagtt ttcagatact 58980

attattacat accaaatcgc gaatgtcaaa agatatttga aaatcccaca cggtgtgtgg 59040

aattagtagg cagtcgaaat tggttacact gaaaatagtt atgcactagc atataaaaat 59100

ggggagccga agctccccag ttaacagata ttacacaggc tctgtaggaa ccttaacggt 59160

tactgttgca gtgtcggtct tattgccgtc agctgtttta acagtaatga ctacagtact 59220

atctgcagct aagtcagcgg gaacagttac cgtaccatcc gcatctacag tagctttggt 59280

agggtcagca gaagtgtaag ttacagactt attggtcgcg ttagctgggg ctacggtacc 59340

agtaagcttg ccggtcttac ctgcttcgat tgtaatcgtc ttaggtgaca tagtgacacc 59400

ggtaactgct accataacag gtttggttgc ttcttcatat gcttcctcaa actgtttcca 59460

ggttctacga ttagtcgcag cgtagccgta ctccttacgc agaagctggt aagtgagatt 59520

cgctttaaca gttgccatca cattgtgagg ctctggcagt ccgttaggga atagtgcttt 59580

taaagcgtta taatcaatca ttctttttcc tcgtctttat ttggtgcgcc accttcttgt 59640

ccacttactc cggtagctga tccagctacg ttggcaggga tgcgaatttt cttcatctgc 59700

tcgtcagcca gttcctcata accaagctct atacgacctt cgttaccagt aaggatacca 59760

ttgttgacta gtgcagttac gaatttagcc tctttctcct tgtcaggagt tagtgctact 59820

acgtctttag tattgggcgt tactttaaaa ccgaagaaga acgtaagaga gctacatact 59880

ttattgagca taggcacaat agtcatgtag tagaacagct caatgttcgg tcgaatattg 59940

gcgttgttac ccccatcgat caatagttgt gggactccga gagcgataca tacgtcttta 60000

ttaaaacgag cgatatcgtt ctcgaaatcg agatctttaa aggaggagat ttgggagtat 60060

ggcttagcct tcatcccgcc gtctagaatg agcacagttg attggccggt actagggtta 60120

tagtccagct gaagctcttc ttgtttacgt tcacggagct ttttatttag gatttcatct 60180

gtttctagaa taagaccgat aaccgtacca ttgtccagga atttctcctt gaactcaagc 60240

attttctcac gcttagtaag tgagttaatc acggtagcta cgcgtgactg acctgtgatc 60300

tgggagttaa taccactatt ctggccgtta tctttgatga agataatttc atcaacgcga 60360

tagtcgatca tattattaaa gacgaatttg ttaacgaatt ttttgtcatc tgcttttact 60420

tccattaggg cagcaggcag atggtacaga gacgaaccgt cccaatggat gtacgcacag 60480

ccttcgaata gaaggtcaga cactattagg cgtctaaaag tactggaatc catgtacggg 60540

ttagggcgaa cattaagcag cgtctcaaga gttttactcc tgatcgtgcc ataggttgtt 60600

attgttttat actgttcacc tacggtgtag gagcactcag cggcgctgtc aatcaccatg 60660

ttcgcggatc tattaaggat ctcaatagac gaataggctt tgccagtcgt gaatggcttg 60720

acgttagtac ggtgactaac atcctccaag tccctgatta tgcgttgtcc gcggtttagt 60780

ttagtaacta accagtcacg aatagccatt ataggaacct tgcgaatcct gatttctcag 60840

tcttgacgtc agtcggaagc cacttcgcaa agcctgatct ttcgccagtg ttgcttgtac 60900

gaggtgcctc tggattcata catctttcac gttgtctctc aacccaaatc ttctgtttgt 60960

tagctgaaaa caacggcggt tctttcgtat agaccttgtg cagggtctga tgatgaaaga 61020

cacataaggt gaccgtgtcc tctactagct catgccaata atgtttatag aacttatccc 61080

gattacttag gacgacttct gagtcagtga aatccagttg gaattcttta gcaaagtttt 61140

taactagtaa ggccacagtc gagtagtggt gtagctccag gttttcctgt gagtcacaaa 61200

tggcgcaaca ggtgcctctt ttgtactggg ctttgattcc atcacgcatt atggagattg 61260

catctctctt atattttaca ttggaagcca aagtgtttct cctcttagtt gggaaaatac 61320

tacttcgggt acagcaatta aatattcctc tcattcaccc tgatgtctat gagatctctc 61380

aaggtatgaa tatattataa ctgccacaca cgaaattgta aagtgaattt tataaagttg 61440

gaacggaatt tgtactcact actatccgtt ccaactcagc tcttatttgc cacgggaaat 61500

cgagtagatg ccgtaacgca gtgcatcaca taagtgagag ttggcatcat gacgaggttt 61560

ctctctggag agcttctcct ccccttcctg gaagtcccac ttgtagttct ggagtgcgtg 61620

aattaacgca gtgcatgagg cgtcgacgat aatcttgccc tgctggaata aagccgctag 61680

gcacgctagg ccatccagga cagatttctt agcaggagca gaagatattt catgctcgta 61740

tgccaaatcc tgtcggaact gtgcggctgc tgagtcaacg aagatacggt ctacgttata 61800

ccggtctata cagtgttgta tgtacatggc atgctgtgct gtagtcttct ctgcctgctg 61860

atattcctca aggatatagt aaacgtcctg atcatagtgg tacttaatgg taaggactgc 61920

tgttgggtct ctgtaaccaa cgtcgatacc tagaatggtt tcgaactcgt ggtctgctgc 61980

aaagaagtga cccatacctg caagatcctg tacatgctcg gaaacgctaa aggtatcgta 62040

gatctgacct tcgaatacgg agaagtccgc ctcatattcc tgtttgaaat agttcttaga 62100

tacagtctta cgtgcttctt cgatatctgc aagagatacg cgagggttat ctcggtatgt 62160

accgtggatt gatacccact gcggaagatc ttctcggaac ccctgctcgt agaaacgttt 62220

gaaccagtta ccaccacgag gagtagagat aaacagggct ttagagttag gtttgtccag 62280

tgtaggacgg agctggatat cgaaagcgtc accaccaacg tcggagattg ctgcttcgtc 62340

aaagataata aagtcatagg aacgaccaac cgcggagtca gcctgcgcag cagaagctag 62400

cttaaagagc gaaccgttag caagttcaat ttctttatct ttggcgttct cacgctcagt 62460

ttgaaggcca tatttcttaa tcagaccttt gatctgcgcc cacccgatgt ttgccaggga 62520

gtagttcgga gctactacga gcaccttaac gttaggctct aggagtttga ggaagcctag 62580

agtatatgca atgaacgact tgccaacacg acgggatacg catgctgtaa tgaaacggtg 62640

acgcgggtct tccagtgcat ttatgattgc gcactgcgga ccatttgggg tgatgccctc 62700

ggtggccagc aagccggaca ccgggaattt aaagaatcgt ttatcaacac caaaatccac 62760

cacgtcagtc gtattaatat aactacgtga gatttccatt acttaccagc ccccacaatg 62820

cgtgacagga gatccgtata gttagagtcg tgaccacctg ccaagttgat ctgagtatta 62880

gtctggtgta caggagcttt agcctgcttc accttctcat actcgatctg catcttcatc 62940

tcatccatct tcattttgtg catgagtttg aggatatcca taatatccat ctctgaaccc 63000

attccagttt cctccagttc ttccatcttc atggttagaa cagtgtctag aataccaaag 63060

aatttatcac ggttacggaa gccagattcc atgaagatat ccgtaaggta cgctttgacc 63120

tcaggtttac gcataatctc acggaattta ggctcttcca tgccaacagc taacgctgct 63180

ttcgcaacgt cgctgccaga ctccaggtag gcctcgataa ctagcatgcc ttccggagac 63240

attgcatctg gtacaattaa atcattgctc atattgcctc cttaggcaag cctttgcaca 63300

gcaatcctaa cctcaggaag aatcacgcgc atgttcataa tattgctcat ctcaacgtta 63360

acccaaacct caacactacc gtcagcccta gctatcagcc aatagataat ggcataatcg 63420

ccctgagtgg cagagttggt agtagtaggt gcccacatag ccttcatttg catggcgttg 63480

tgcccaggaa taaccccaca ctgggttacg gtcccgcgta taaagtggaa cggcacacac 63540

atgttaactg gaagacacat gatttgatgc acacgtttct ggaagtgatt tccgaaaatt 63600

ctcagcctac tatctacctc gctccactgg gtaagatctt ctagagggtt ataacatcca 63660

atccctgcag cagcaatcca ctcatcgttt ttccagtcta gagtgacgac gcaagcccca 63720

tttcgggagt tattaacccc taaccacaag gtagccaggt ggtgactagc attaccgcta 63780

gtacgtaggt tccctccaat atcagcagag ccggtaccgc ccactaggcg aagaggtcga 63840

gttgcttcgg accatactgg accccactgg tttccaattt ccggagggtt ggattttaca 63900

taccactgcg catcagatct aaaattgtaa actcctacag tggttacatg catctcactt 63960

atgttacctt gcccaaattc cgcaccatta tctggtcgag ttagaggctg attgaagtga 64020

acatatccat tattaccaac agtagggttg ccactaaatc tagcaacatt ggtcgcaata 64080

actcggatat ccggcctatt acctgggctg tagtttatat cgttctgatt tatgaacttc 64140

cacccagtgt tcattaggtt tataccgttt acaatgaact ctctagggct gattttaatc 64200

tcctggttgc gggagccaaa tacgttctct gcgtagaacc cctgcccatt gtatttcata 64260

ttagtaatat accagcgaac acgtttagga acacggaagt tattgtcacg gtaaatggca 64320

ttgttacccc aaccactacc agcattgttg ttatctgtgt tctcccaccc cataaagtta 64380

ttgggcggac cacggaaaaa acctgctttg tactgaacct cctgataaga ctcagtctgg 64440

atgttatgag cataaggacc accaacggga ttagacccct taccgtatct aggccccata 64500

tgtccgtaca tattacggtt gagagtctca ccacgcaaac atatactatt aactcctagg 64560

gtacgcatcc atgggtggcg catagcatca gcaccaatag taagtggtct attgggcgga 64620

gacacagaac cggctatatt gccactaaaa gcccccctat agagcaccca tccagcttta 64680

ataatagtct caaagttagg acgtatagga gctccaaccg gcggcccagg ccctctgtcc 64740

ccccattctg agttaacgcc ccaggtgtac atacacccag taccatctcg tagcttctcg 64800

ttaatagtac ctggcgtctc ttcgaaatag aaactaatat ccatgtgtaa gtctgcagaa 64860

gcacaaacgt tagtcttcat actagccata gtacctgcag aagcctggga accgacagta 64920

ttactaaagt aagcgttata cgctttagcg ccaacgccta gagaagtacc ataaatgaaa 64980

cgtctagtac catcctcaaa ctcaacctca gttaagacaa ccctgtcgta gtctgcggac 65040

agtacatgaa taatcctatc tggcattcta gtacaacgat accaatcacc accatcccag 65100

aggtctcttt cgtgagtttc caaaaccaca acgtgaggca tgtcactatg gaatatagta 65160

tcccaacctg gatttgtatg gttattgacg tctttattgt tgccagaggt gagagacaac 65220

acttttttgt cgcctatcct tcctgcgtaa aagcccataa aaacctcaaa atctcacttg 65280

ctaacaagtg acttttataa tataatatta ttataaatta aatcaaccgc caagtaaacc 65340

agatttttta aaaccatcta ggaggaccac tatggaagta gttataggag cacttgtttt 65400

actctcaatc gtactatttg tcattaccgt aaagcaaggt aagataatca aacggctaga 65460

acgcactaac ggggtgttgc aaaagtctta tgacaaccaa acccgtttgc tgcataaggc 65520

gcagttaaac ctgtctgaat gcaaggcaga actagaatca gcaaacaaaa tctacattac 65580

taagggtatg gtgtaaaaca tgactattgt attaattttc acaacattct ttttcctggc 65640

aacagtttgg ttcggtgtgc gggcacatga cctgcggaac gcggtagtag cggcagatct 65700

tcgtaacaaa agtctgcatc aagagatcct tcaaactcgg gcggaacgtc aagtagcgat 65760

ctcgaaacac caacgagtca tgaacggtct tcggaatgac ccgagcaacc cgtactacat 65820

ccctccagtg acaccgcagg tagcgagacg caagcagaat cgggggaact cgggaagttc 65880

tcggcagcta actaataatt cttcatcgaa ctcgggaagt tctcggagcg atgacgggtc 65940

gacggcggca atcatagcta caaccgcggc ggttgctaca tatagcgggt atgactcggg 66000

aagttcttac tgcgacagcg gcagtagcag tagtagcttt gattcgggat gttctttctg 66060

atgaaaccca ttcctctaga ggttctagag tcagtattct acgacccaga taccggggaa 66120

gctcattgcg acctcggtag tattaaacgg gttgacgatg gttttatata tgtacaccca 66180

aggctcgggc agttctccct ggcacgagtg ctgtggatgc ttgaaaccgg ggaagatccc 66240

ggagagttct atatagacca caaagatact gacccgttca acaacatttt cagtaatctg 66300

aggaaggcct caccctctca aaaccaacac aataaatcgt taaataagaa caatacctcc 66360

ggagttaagg gtgtgtactg gtgtactcgg gctaaaaagt ggagaggacg tatacttgta 66420

ggaggtaagt gtgtgtggag caagaatttt actgagttag aggacgccgc tcgggagatt 66480

tctcgggcaa gagcggagct acacggggag ttctccagag attcctaatt agcgctaaac 66540

ccaaaatctt gaaaattcat aaagttttac gtggggatgg gcttagaggg ttggggggtg 66600

gtatggtagt ctgaaaacgc ccctcctggt actactagca aacaaactat tagtacccta 66660

actatttcgc tagggtacta ttagctttct tatgatgcga tggctaacga ttgaatgaat 66720

tgttgcggct taactccata gtcgcttctt tcttcttcgg tcataccttc ccagcagtgg 66780

gttaaacgtt cgcaaagata ttgataatca ttatcatcgt ccagcgcttc atctatgaat 66840

gactcacccg caaggcgcac accaatagac agaatatcgt taattgcggt agcgtccatc 66900

gtttgaaggc cagcagcagc agcagcagcc aacacgcctt tattatcgtc tatcatggtg 66960

atagtagcgt tcgggtattc agctttaagc atttcgaaat aatgcgtttt atagatacca 67020

tctttcgaat agtacacctc tttataatca gcagcgccaa tatatcggtg caatacatcg 67080

cgggatagta tctgaatatt accaccgcgc cccgccctga tacgttgttt ccgtaggaaa 67140

tagtaatcac tttttcccat atagcgagcc gtaacaataa tgtttaatac agtgggatca 67200

ttaagcgatg cccgcatata ttcaaccaaa ggtaaaagag tatcggccat aattgcatca 67260

tgtacgcaag ccttttcccg gtacatgttt aaatctaagt tccctctatc atccatacac 67320

gggaacacgc gggcaaagga attaataaca gttccgtcta aatcccataa cttaattgcc 67380

ttaattgcca gtttattaaa agccattttc atttctccgg tttcggggtt gttggtaatt 67440

aatcaagcga gctatattat aactcgcttt gttaattatc agaagaataa agttaaggca 67500

tcggctaatt cagccggttt aatccgggta gctagtaccg ggacaattgc gagcggcggc 67560

gtatattcgc tagaagaata atccattaca tcgcctaaca gataagtatc atcataatca 67620

ttttcgctta cgacgataaa cataaggcca gcggcggtgg cgtcaatctc tacgatctcg 67680

cagatatcaa cctcataaag aatagaatcg ggcgcgacta attgcgacac aatgccggat 67740

tctttaaatt cagcggggcg cgggaggata gcggctagag cttttaaaac agtgtcgccg 67800

cccaccgtgt taactttctg atagctaaca tgcgggcgcc cttcgctatc gcgggtgata 67860

accagactgt tttctacgac gttggacgcg gtgaaagatt tacgattgtt atagatgaaa 67920

gtaagtttca tttgtttctc cagcttattt atttaggggt tatttattgc cggggtaatt 67980

gccccggctt ttttgttatg caaagaaaac gccgtcttta aagtcaatca aggtacgttg 68040

gccgttttca taggtgatta gatgagtctg tgaccagcta gacgcgccga tattgtaacc 68100

catatcgagg gaaccagcga cgccagcagt ataaacgccg ccgtagatgc taggcgtatg 68160

cgtatggccc gtgttcatct tgccgagctt acggaatcct ttcgggttgc cgcgagcgcc 68220

gttaatgccg ttgtgaccgt gggaaccgca ttcgatgccc gcgattttca tcgattcatc 68280

cgtggttagg aagatcgcag caaaatcgca gccagcaaca ttgcgcaggg cgtaatctag 68340

tacgttaaaa gtatcgtctt tgttttcgat tgcctcataa atcgcagcat tcaggcgata 68400

gtaaagatgg ccgttcgccg gatcttgctg aatgttagcc ttgctatcat ccagccagcg 68460

ggatagcgca agatcgtggt tggattcaac aatgaccgtt tgactgaact cacgttccat 68520

tgcttctagt acgcgccccg tatcgatcag gtcgtcaatt accttgtcac gtccggcggc 68580

atattgtttc gcaaggaaaa cgccactagc gcggttgtga tggttgcgtg acgtaaagtc 68640

atgcacatca tgcacaatct ggtaacgagg gcgcaggata tcgactagcg cggttccgct 68700

agggttgtat tcccagcttg ccgccgcgac agcgtgatcc agtttttcgg cgtgtatgtc 68760

accatattgc agcgcggcaa catgcccggt tacttcttcg ccaccgttaa cagtaaattt 68820

atggttaaga tcgtaaaaca tcccgctttc gtccatcgtc tcaagctggc gagcaaagaa 68880

gttaccgttg tcatcgatct ctaccagcaa agcgccatag ttatgcagcg cttcggcctt 68940

ctggcccgct ttttgctgaa tataattttt cagcgtagct gtgccagttg aatacatacg 69000

gcgcaccgtg tcgcccttca ttgccgggac actttcggcg gtgattttag cgtgaccaat 69060

agccagccct ttcaggccgt aggcggtcgc tgtttcacca aaaccggaca gcggaaaatc 69120

agcagtcggc agaatgttaa tttccgccat gaatgcaaaa cctgtttcac gattgcccaa 69180

aaacacgttt tcatcacaaa tgaaatttga gaaagcatta tcatatttca gttcatcgtt 69240

gccttgccca ttctggaaac cttttttgtt gtaggcatat ttgctcacta gcagggttgc 69300

gccgagatat ttcgcggcct cctgtaaagt tttccagaag ttagcatgag ggaaggtatt 69360

attctgaatc gacgttaaca gaaaacgctt acccggaatt accttccagc tttcgacgct 69420

agaattaagc tgaccagcgg caacggggcg ggaatcttcc accgcaacac gttgggccgc 69480

aggtttaaca ggcttgttat tatccagcca atcgcaaatt tcgctagaat gcttcgccgt 69540

cccgtaatgc tctttgctca attcgtcgca gatctccagc tttttagcgc gcagacgttt 69600

accccaaaaa ttgaggttat ttgcggcggt taaaatagct ttttgtttct caattgcaat 69660

gatcattata taaattctcc agttatggga tataggcaga attgccaaat ataacgcctt 69720

gttgctagtg gcgttataat ttgcgactct aaactattgc cgggataatg ctggcggata 69780

ttccaaaaac tacagctaga ataataaaga ttattgacca gcggcggcaa atattcgctt 69840

tcttaaacca gaagtcacgg cggaataaat ccatttgttc actgcctatt tccatgaaat 69900

tataataacc atagagacaa gcggcggcga aaaagccagc gataagaatt aaggattcag 69960

tagggaaaaa gatcatttta caacctcctt ttcttctacg ctgaaagcgt attccattac 70020

ccaaatttca cgggagggta attccaacat ttccggctta aatatttcgc ggttaattgc 70080

gataccgtaa tgatcattgt cggggttgac gtataaaacg acgaattccg ggactttgac 70140

actagggggc gtcataatcg cgtcattctg ataacctacg cggattaatt catccacaac 70200

ggttcccgtt aatttaataa cggagccttt aattaaagcc atttttattt ctccagttat 70260

gggggacaaa atatttaatt atgcgccccg ctagggaggc gcattataat tattctgccg 70320

actcttttac ttcatcctga acgccaacca tacgggcgat aacgtccagt tgatccagct 70380

tcatttgttc caaacttgcc agaccgtcgg catcttcgat caggccgtcg gcaatagcgt 70440

gctgagtgag aacgcgcaca tagtgagctt tacgcaggga ggaaccgccg ccgactttgc 70500

gcggcttatc ggacttctga taaacctttg cgctaaccag tttagaacgc actttaacat 70560

gcgattcagc accgacagcc tttgcaatgt caatcagacc ttgcgagttg gcaacctcca 70620

gaccttcgga tgcaataatg ccttcataca tagaaatcgc ggtagcggcg tttgtttcgt 70680

tccatgcgaa tttttcggtt ttagtagcag tcatgatata tctccagttt tatttaaggg 70740

gttaggccag aaagttagcc gctatatatt ctagctagaa tatatagcga aaactcttta 70800

ttttagtttt caatttaaag ctatttaaag cggcattgta tatatacgct gcctttaata 70860

attacgctat tacgtctatt tcacgctata gattcgtgtt aactcacaat tgccgttcaa 70920

agcatgatat aagtttcagc acataagttt aatttgcgca ccataacatt gcctgcgctg 70980

catggaatat acatcggaag tctaacatat ggggaagcat cccattattt accggggtta 71040

aacttattgg ctgttaagcg acagccagcc acttatcatc tttgcgaatg actttcacca 71100

cgtcgccgga atctacccgg acgctgtaaa gttttaaatc gctgtttttt gctttttccg 71160

tttcggcgta taccgcatta attttatcaa acgggatcat cgccgcccct ttgatatatc 71220

cgattttttc attttctccc ggcttactta cgtcgccagt aacgaaagga ataaaaacgg 71280

aatcaccgat cattggggtt ttaacgtttt gcatgtttct tactccagtt tagtttattg 71340

ggttatccgg ttaacactct gatattttag agtgttaaca gaaaactcaa ttacccttac 71400

tgagagaatc gacttttcca aatttttaaa gagcggtgtt gcttattgag attctataat 71460

aaagcgttat cggcagactg tcaagcgtta ttttgtaaag attttaaata agccatcatg 71520

ttatcccaaa tcatcggcaa gccttgctga cctccgcgct gataagagcg gtaacgccgc 71580

gccatatcgc gctgcatttt gaccagttcc gaacttgcca ttttgttcaa ttttgctgcc 71640

ggtttagatg atattgcaaa gcgtttcatg ttgtcaacct ttaattagtg gagtgtatga 71700

tttcttttag tttgcataat gatttgcccg tctttatgaa tgaaagctaa atctacgtcg 71760

tacacgttta gataagtctc tataaaatgt tcggcgtctg ctactgtgaa ctcgtttaca 71820

atctcgctac tcattacgtt ttcttttaac atgttttcgg tttccttatt aagtaaagaa 71880

gccaataacg ctttttatag aatcccaaat tgttaaagag cagtgtaggg cggggacaga 71940

ctatacttgt ttcggccttt cctttcgcgg tagtcggggc aatgttgccg cctcctgata 72000

cctgactact agtgaaacgc tttcgtgttt cccgtttcgt cttgccgccc tacgagataa 72060

ataataacac aatggcgttt agccgcaagc ggagaattgt aaagaagcgt aaagagaaaa 72120

caggcccacg atagatagga agccgcgcgc acgtgacaca atatttaaag aaagtcaacg 72180

aatattttta ctatttttct tcaaaagggg ttgacaaaat ctatttcaca cgaggtgagg 72240

agatcgcctc atacccggta tgattcatcg gcttttatct aaaaccgctt agaatcgatt 72300

ctagagcgtt ttagaccctg ttaataactt atacaaaaag caaaaatgaa atttaattag 72360

ttatccacta gacaaatgat tatttttatg aaaacgcaaa ataatgcttg cgtttatttt 72420

atgctgtact cctgttttcc gggcaagtta tccacagcac aaaaataact tgacaagctg 72480

agaagcggta taacgagata tccccagact tatccacagg ttatcctact gtatatttgt 72540

acagtatatt ccggcagcgg taatactcta atatacccct agaacgctct ataacgcatt 72600

ctaagcgctt taaatttaga agccatatta aaggccattg ctggaggggg cgcagaaaaa 72660

caaaaagccc gctcattata agcaggctta ttattagtta gctaactatt agcggaatac 72720

cgtttcaatt gtttcgccgc tagagcatac cgacccgcca cgataaaaca ggcgttcggt 72780

tttatatttg gttagcagat catagagatc cagatcatcg gaaagcgggt aagattcccc 72840

cagcgcggaa acggaaacag gtttacccgc taccagatca cggcaaatca gaatcagcaa 72900

aggccagcta atattgatag catcgccccg caatccgatt ttgagggtag cgacttcatc 72960

aatatgcctt gcattctggc ggctaacata ttggatcacg gtttccatcg ttttatagtg 73020

agccagaaaa tatttgttga catagatgta aatcataggt atacgacccc gctaaccttc 73080

caaccggatt ttaaaccttc ctcaacatga aacatggttt tctccaataa tggggggcgg 73140

ctagagattc agccgccggg aaggggattt tacagcttat cgcggaaagt atcaagccgg 73200

ttgtttagct ctttaatcgc gtcggcatgg atttcgtcat acgttgacac gatatccgcc 73260

agctcatcca tagttagcga actaacaata acggacgttt tcacctccag cttttccggg 73320

atcgggacgg ctggtggctc gtcgcttatg gcaaacgtac cggagcggag caggaaaaca 73380

gagataccgg tttctccctc ctcgcaatcg atttcatagc tgctatcacc gatggacaca 73440

tcaaaaccat agccatacgt gccaataata ggcaatggta tgcctattag ctcgtcgtga 73500

tccgggtagc aatcgcggcg gtgaatttgt tcggctaaat ccgggccgct ttctttagta 73560

acgaaaatag acaagctatt actactacta gtggcttgca agtattccca aacgcgggca 73620

agcgtcattt tctcgccttc aaaagtagcg tttaactttt ccataacatt ctccagttag 73680

ttagcagggt aattattata gcgccccatt atagaggcgc tagatataat tattctgcta 73740

cgtcgttttc aatcaggcta gaaagattga cgcctttcaa tacttcgtca atcatttcgc 73800

ctacattgaa actttgtacc agttccaaca tggcggcttg cattgcagcg tcagccgcaa 73860

tcaccgcttt gcggttgttc ggcgcatact ggctaaccgc gaaattcagc aggttagcaa 73920

ttaccacacg acctaccgcc gtgtcaacat aaccgcgaac cataaacggc gctttgctgg 73980

cggcgatgcc agaaactttt ttcaggacga tagaaccggc ttccagtttg gcagcgttta 74040

cggcagcgtt tttgttagcg gcaacgatag cggtagcagt agatttgata gtattcattt 74100

gtaaagctcc agtctcaaaa ttattagggt taactacatt ttcagtaaca gccggggcga 74160

cttcttctag ctcgccatca taacgataat ttccagtcct tgccccttct tcgatttcga 74220

tatcgaagaa gttacagggt aacaggatgc taccgtcctt gtcaagcaca aaaatcatca 74280

tttcgctaga aattcgtgct ggtggtagtt ccagatgatc gcacagattt ttaacccatg 74340

cgcgggcatc agtgaaagca agcagttcgc tttcatggta gcaaaaacgt cgtgacgctt 74400

gcttaccctc ggacgcttta tacaaataag cgtccgtagt agtagacact atcagatcaa 74460

taggctggct gtcaaccaaa tattgatcat cgtgataaat aacaatcgcc gcgccggggt 74520

tggctagagc gtagtcacgg caatgctcaa aggcatagcc ggatctactt tccatattcg 74580

agcggtaaac gcccaaaata tgaccaatag aggcgcactt actgccgtct aacaggttgc 74640

gagcgccacc gcgaaccatc ggcaaattag caacgggggt aaacttctgt aacattttct 74700

gttactcctt tgtttggctg agaatctatt atagcaagat tctccgcttt ttagcaagca 74760

aaattttttt atgcttgccg ggagatcaaa ctatagggaa atcggatttg cctgtctact 74820

actaaaaata gtagttgctt cccgctagag ttatgttatt attactactc caaatagagg 74880

ggatcgaaaa atggcttttt caatgttggc gctcggttta gtcggttcta tgatggtttt 74940

gggctttatc gctttttgcg gctatgccct ctatgatacc ttgttcaata aggaggcttt 75000

ttaatgagaa ctttgcgcgg tggtagtccc aaaagccgta gcaacaatac ttaccaattg 75060

aacgttattc gtgacggtca gaagaaaggc ggtgacggtg gcggtggcgg cggcggtgag 75120

tggggttttc gtgtcatcat ggttattatt atgaccctag tctttttgca gagctgccaa 75180

tgatacttac aatcctattt attagcgtgc tatatatttt gcccggcctg ctggcgctag 75240

aggtctggtc acgatcaccg gttgactccg agcgcgaatt agagcgcgaa aaagcaaagc 75300

gtgacggctg cccgttgcta tagggcggct tttcctccac cgcgtgaccc cttactaaaa 75360

tacctccccc aaaattaaat cgcttagagc gcgttctaga gcgcttaaaa tcgatatcag 75420

cagaaagtgt tgctgggaaa tactgtataa atatacagta ggataacctg ttgataagtc 75480

tgttgataac tcgctaccga tcgattgagg cgtcaaccta atttacaatt ttgtataact 75540

ctggggataa cttaaatgat agtgtttctc acttcctttc cgaaatgcaa atcattctca 75600

ttcgcattca gcttatcaaa cgagaataat tatcattcgc attcaacttc tcaaatgcga 75660

atcgttctca ttcgtatttg catttccgac ccccggccct tcctgcgctt atgtgcgaat 75720

ccgacaattt gtcaagcaaa atattacgtg aggctgctag ggtatgtgca aatccgatga 75780

aaatttattt ttaccgccct gggggcatgt gcaaatccga cactaatatg tgcaaatccg 75840

atgataattt ttagggggaa ggcgcgcagt ttgctgcagc gcagcggtgg gcgcgagttt 75900

gggtgagtat gtgcaaatcc gatgggtatt tttgggggag ggataaatgg ggttaattgg 75960

ggcaattcgg ggatgatggg ggcaaggggg cagataaggg aaaatattat gagttaaatg 76020

ggggtaaagg ggttgacaca gaaaaaattc ctgtggctct aaaaaacaag cgaactcacg 76080

gtgacacacc gtgtaaaaag gcttgaaatt tcaggagata ttttataatt gcagaatcga 76140

agattttgat ccacagctac cgttcgttag agataatgtg catatccgac aaccatttga 76200

gtatgtgcaa atccgatgat gatttttata tgtgcatatc cgatgatgat ttttatatgt 76260

gcatatccga ccatgttttg aaattccaga aaacctggaa atgcctaacg tattaaatat 76320

ggacgagcta gaatcagatt gtggattctc tagctgtgtg caaatccgat aatgtttgac 76380

gcttaaaact tgggcaaatg atgtgagttt gtgtgggaac ttcgtgagga ttttgtggag 76440

tgacgcttag gacttgggca gctagcgttt taatgtggga aatgtgtgag gacttcgtga 76500

gatgtgtgga acttcgtgga attgtgtgag tttctaggaa ttgctttccg aaaaagtggg 76560

ttggaaaata accgccctcc ccttaggtgt gtagaaataa ccgccctgta tagaaagatg 76620

actagagttc aaccctagag ccgcgaaacg atggtgtgta aggattacct acttttaaac 76680

gtgagtaatc gtgagttcat tcccacgttt ccctattttc tccttagttt tcagtaatta 76740

ataattcccc ttagggtttt aacgagctat cgcacacccc ggctagcgat actgtgcaga 76800

ttgatcaatt tttgtaattt cgcactaagt gtcttgagtc gggacagggc cctgacactt 76860

acgaaattga aaaatcaata tctgcacatc tctagcggat gtgttaacta tctatttaat 76920

ctaacttttt tatcttatag agttattcta acatacatct caaataatgt caagaatttt 76980

tacgggagtg tttgaaaaag tgtcacgggg tagatgttta ccccgtgaac tcgtagacta 77040

cagttgagaa cgtaggttct ctaactcagt gaggaaggca ggattcgttt gatcgaaatc 77100

cttaatgagg aggtgctgat caaaggagaa ttcatagtct tctccgtaca gcttaatgaa 77160

gagatctgga tgttcacgtt tcaacacaac atgcgctacg atactcgggg taatctcacc 77220

ttcttgctgg tggtaatcga atagctgtag agtttcatgt ctagtttctg gtttagctgg 77280

ttcttctttc ttgatgcccc aaggagtgac aaacttagga tcaccacctg ggaagacgga 77340

tgctcgcatc ttataggcgt aagagttaag atctgtcatc ttggatgttt gccatgctgc 77400

aaagatttca tgtttacctt cagatgctct gactggtaaa taatgatcag ggtagctggt 77460

taatgcacaa cggaatggat caccgttata gttaggggca tgagagccat aaagtgtatc 77520

atgttttagt ggttcatctt ctataatata gagctcttta atctgcggat aagagaacca 77580

ctgattgaaa accttaacag cgaagcgatg tgcgtatggt gacatcttga gaacgtgata 77640

cttcgcccct agatcatctt ttgccgattt accgtcttct gttactgcgt aacgtctaca 77700

gaacatctct acgagtctac gctcgttagt tgtgagagtt gagtatttac gctggtgcag 77760

ctcataaagc tcctctagca ttccctccag cttggttacc atttcttccg ggtacttcgg 77820

gaatggtttt tctactgcgt tcagtacagt gttagacgaa cttttacgtg atctttgtag 77880

tgcattttta aatctgctca ttttctttcc tcttatagtc cattggactc tttttatagc 77940

cacgggattg tggctcttaa cttacttcat tccacctagg atgtgagaac ggctctctac 78000

ctgtcaagcg atccatcatc ttccggtgct ctcgctctct gtgttcatta aacacctgaa 78060

gagcggcgaa actgtccact ggcgtgtacg gcacgccgtt aactttgagg atatcctcgc 78120

ctctgatctt gaatagcggg ttgtcctgct gggccttagc gtggcattca ctcaagtact 78180

ctgcgaaagg tttgccatct tcccgagtac acagggtacg aagaaggtag ctacaattct 78240

ctccaaccgg agtccatact tcatattttt cgttcattgt gttatcctct tacataaaaa 78300

aatcttcatc ggattcggct atttctttat aaaagccgtg atatgctgat gttgcttcgc 78360

taggtgctgc catgtcgaat aagcgtgctc tttgttttaa ttctgcttta ttttggcact 78420

gcctaatcat ttcttcgact tcttgctgca agcgtgcatc tacacgaacc accagctcac 78480

cttggtgaat cgacccagtt ctgaaggtta acatcgtgag atagcctggg tgctgtcgag 78540

actttttgag aaccacgtta gtatacgctg ttaactcatg tacaaatact gcacctggga 78600

acgcataagg agttagcttc ttacgagctt ttactgcctt aacatctatt aaatgaaaga 78660

agtctttcgg agtcttggat atgtcgtccg gtacttctac ttggaactga ttccagagga 78720

tacgtacttt gctttcagac atgccgtaga caatgtacgt ttcgttagct tcttcaaaat 78780

caactgtaca gaataacata tcctagccct cttacttgtt gtagaactca gtagcgcgat 78840

tccacctctg gatgctctcg acatgggctt gaccccagat atttctggag ttagtcaatg 78900

cagaaacatg cggctgaata agttcgaact taccaacggt agccccacta gtcagcagta 78960

acgaggttaa cgcttcgaac ttaacggtat cgctaccgga cagctcactt actgccttaa 79020

ccttgtcaat tatagagatc atcttagcct cttcacccac gaacgtaaag cgcaggttgc 79080

ggaagcggaa ggagatagct gctacactcg gcttgctaga gtccggggag tagttcggat 79140

ggaacttgat ctcggagact gattggtcag tcagatagtt ggtgctcgga ttattcaggg 79200

aatcgtattt catctttaac ctccaaaggc tttatcaatt tactggagtt attataccaa 79260

ataatggagt ctccgtcaat tgaaaatttg tgatagtatg ctggcacggt gtaacttcca 79320

taatccgtaa ctctagtaac catgcggtgt ctgcattttt ggcaaccatt gccctcaagg 79380

tggcttctag cggtttgcat gaagtaatcc tgatggtctg ggcaccatat ttccaccagc 79440

tgatttaagc tgtgaaactc tagcttctca tatccgaaga atactccatg agcgtctaga 79500

gcacggttaa taaagatgag gttcttagca tcttgcctga aatctggcct cagttgcttt 79560

atcttattat ggttgatcga accgtcgcgt ttaaggaact gattaatggg gaaggattta 79620

gcttcccata ctagttcttg atttatcttc tgtcttaatt cttccactac tcaaattcct 79680

ttttcaacct ctcgtatagg tctctggatt gcttccagtt aaggtatact ctattaggtt 79740

gattacctcc cccacgctga gtaagtataa aacactcttt cctaatcttt tcgatagtaa 79800

ctgctgattg atctacagga ttttctcccc gtaaatagtt gtctatagat ttcatttaat 79860

atccttaaac cacgaaaggc cagagcaatt agccctggcc tctttgttag gtgaacagat 79920

ccagaaactc ctctggataa tcggaaggat ctccaaagtc gatgtgatct gcgttgaccg 79980

ggtagccttc tttcgtcttg atgccctgaa gaacatgggc caacacgtca aagtctacac 80040

tgctgttatc acaacaggta gcccaggctt cctgacggtg gacgcatttg ccatccacca 80100

taacctcaac accgtagcca gtattccagc aaccgtattc gcaatccccg gaatcttctt 80160

ctaggaagtt taccacaacg cgtttcttag acatttgtca cctcttagtg aatagtaccg 80220

tcgatgcctt ccacatggat atcgattgcc attttcagca tcgactccga tttatcaaac 80280

tctttcttcg aagccaggag tgcttcacca cgagctttcc catactctgc aatagcattc 80340

agggtatgtt tcaggatatc gtcggcggat aagccctgag tttgccagtg gacttgagct 80400

gtggcgatgt tcaccataaa cttactcagc tcaacacgct cttcgtctaa cgcctgcatt 80460

acgtgggttt tgcagttata gaaggagttc agacaaatgt cttcttcggt cagaccttca 80520

accagaagca tcttctctac ttgcgccagg cgatcaagcc acggattttg gagcatcaaa 80580

tttttcactt gcatggtata agttcccgtc gttaattggt gcgaatgatt ttgcgttgcg 80640

ttcaggacgt tgtttagcga tccagcccat catcatctgt cgcggcagta caactgctgt 80700

gttctgcagc acttcgtaga tccagtagcg tgcgttctgg tacttaccga actcatacgc 80760

tttcttgaat aagccccaaa ccacgctaag ctctagcgtc tctgcatttg cagtctgtcg 80820

gaacggtatc actttggaac caatgagttc tttcagagcg gagttgatat cctgatgact 80880

gaacgtggtc tcatggaact cgttgaagaa acgatagtcc agagcgttat tagcgttaac 80940

aaacatctgg atgaacagat cgctgaactc ttggtgctca tgattgaaat attgatttaa 81000

aacttcagtt gatgcggcca tctttccacc cgttaattgc tacaagatac atctcgtaaa 81060

tgaatacagt gactggttga attgcttcca tgtagaacgt cgctgggacg ttatggaaga 81120

ctgaaaccac catggagagg aacaatgccc agcctaggaa acggctgggg agttctcgcc 81180

agacctggaa gttgcaatcc aggaagttat agattcgaag atgattaagc attggtcagt 81240

ctccagtaat agtgacgagt attaaactcg aaaggttcgt cggtgatctt agtatgcagc 81300

gtgatgatat ccggggagta ggactttgcc agatctttgc gaaccatcac agtgttaaac 81360

ggagcaccat cagcacgctg aaccacaatt gccaagccta gaggaggaag ctcacacaaa 81420

ggacgccatg aatccttttc cgcctgggtg atttttctct gaaggtttac gaatagctcg 81480

tactctttat cagacatttc cccaccgaag tcagagtaat ggtctagagc ttctaacaga 81540

atatcacgct ctttggagtt aagattcatt tttcttcctt cttaatggtg ttttcaatat 81600

catccagcaa tgctgtgcag ttatcatagt taactttgcc cctgccaaag attctcaaaa 81660

cacaggcgta gtacccggtt aacagaattg ccagaggata cagaggaacc agcattgctg 81720

ccttgatagt accttttaaa ccgaagccgt ggtacttccc agacaggtag ccaacaacta 81780

ccaggtaaag cgctgctaca attggtgaga tcatttctta atctccgtga tcaaccgcat 81840

tttggttgtc ttcgacatgg tggaatcttg gccgattatt tcttcgatct tcgctaggcg 81900

aactaagagt cgttcagccg cagcagagaa ttcatcagcg tctcgtactt gatccatcaa 81960

tttttcgtgg agtccgttat tggtcaatct catcctgcgg ttagcttccc gcagtattga 82020

tacccaaacc gccagacccg ttccagttac gagggctgcc atcaacagcc cggagagaat 82080

ttctagtacc attacttttt cttcgccttt tcacgtttca ggtcacgttc gaagctctca 82140

gcacgacgct cagcaacctg ctggtgttct ttggcccaac gcgcctcatt tttagcgagg 82200

ttgtaggccg cagcattttt gttagtacct tcgtacagag cacgaagtgc cgggagagac 82260

agtttagcaa gctgaccttc gaacccatcc atatccagca ggattaccag taccgcaacc 82320

atttcgtctt tggtcagggt gttagcttgt tcgtcagcag ttttaccagt ggtgtaagag 82380

atagtgttct tagccataat gatttccgtc cgtttcgtta atttatgcgt atattatacc 82440

gaaattctaa ctacttagca agtgaatttt taaacttttt taccaatcga tccggtaagc 82500

gtaaacttca gaatgaatgt gctcttctac cagcttcttg atctctggcc agttcttttg 82560

aacttcatcc agaacgtagt cgtttgaagc atcatcccac tcctcgggaa gtttcatgaa 82620

agagcctgcg tactccagta cgctctccag aacatcggtc aggtaaacta tttccccacg 82680

gttgcagtaa gcgtgttgat aatcccggcg atcttcatta aatggggagt cgctgaggta 82740

atcccccata tgaaggagtt catcggcgaa ctcctcaaat accttgacac gagcagacag 82800

cggtatgctt tcatcacgca tcagcaggtt aaaagaagca cgtgcagtgt taactgcgtg 82860

gcgaagggac tccatatttg cattcagttc gatcattgcg tttttcatat ttgcttcctc 82920

atcaatttat aaagctatta tacagaaaaa ttggctcgga agcaactgaa tttaaaatac 82980

aaatgctacg agcgcccaga ttccgcctac aattgctgca ccgattaatg cagctacgat 83040

cagaaggcca ataaacatct tggccatatc atttcccatt ccagtataca tggttactcc 83100

tcgattacca gtcttctcat gtagtcgttc caccctatac agaatggaga aataccccgg 83160

agtagttcgg tagactggtg ctgcttatag tggtcttctg cagccttagc cccgcgtttc 83220

ttctccgccc ttttattaaa ctcttccagc acaatacgtc cttctagagc ttctttagcg 83280

ataggatact caggccaatc ctcctctaga acgaggtagt ttggaaatcc tactttcccg 83340

tccgcctctc gacttttaga gatatgggat aggatgttgt tcagcctctg aatggaggtt 83400

gaatccagat atttttgggc atctttatgt ttgatgacac tataacgagc ttcaagtttc 83460

atgtgctacc tcaggctgtg aataaaaggt cttccattgg gcgatcttta tggatcgccc 83520

agaactcttc cggttcccag gtttcagtgt ccggggcaac cagaaccgag atattcgcgt 83580

catctgtaaa cacggagttg ccattgtcca gcattgcgac acatttctgc aactcgaaac 83640

caccagcaac tacgaatact tcaccttctt ccaaatcttt gaaaagtttc atgtttcacc 83700

tattaaataa tgtcagcgga accacaggga tcatcacgat ttgtggtgaa tgtgtataat 83760

tgacctagaa ccggcgacgc cacggtcatg cgaccgttaa aggtgccacc tgtgtccaga 83820

tagacacgat tcttccagcg aattgggaac gggacaccag tatggccatg aaacgtgtag 83880

tctactccta cgatttcagg aacatcgact gcgcactcct tggagaagct agagtagcga 83940

tcgaagtacg ggtgcttttc cccactacga tacagattaa acccaacttc ctggattaca 84000

tcacgatccc acagcagtac atccaaacga tgtagaactg gggcagattc gtgttcatac 84060

acaatgtcgt cccacactgg tacagttaca cccatacctt gagcctggta gcgcagaggg 84120

ataccagcat gaactacccc gtagcgcttg cctcggtgtt caaccgtcat catgtacggc 84180

atcttgctgt ccatgtcctc tgcaatacct ttcagggtgt ccgtatcgaa accttccgta 84240

atagtccagc taccaccatt atacatccag ttggcgtagt cgtcttggat catgaattca 84300

tcatggttcc cacgaacaga gcggaatttc gggttgtaca ggaacttcgc tagaacctgt 84360

aggttcttcg ggccacggtc gataagatcc cctacgcaga acacgtagtc acgaccttct 84420

tcatacccag caagtttcag ggcatccatc atcatatcgt actcgccatg aatatctcca 84480

atgaagaaga tattagcatt gtcgggtacg gtaactgttt catgaacgtt cattaatacc 84540

tcgtctataa atagtaacgt tttggcagcg agaagtctga gggctgctgc ctgtgatctc 84600

ttacatattc ccctcgataa gggtcgtata ttacgtattg cactagacct tcgggttccc 84660

aggcaatcag tatttcattg cctattcgtt taaatgcgta cccattctgc ttagcccaca 84720

gtatgcacga gtagtccaag ctcctggcat ctacttttat gccagaaaag cccctctcta 84780

cattgtaggt gatacccttt attaacttat cgagctgcat tttcttatta tagtaggcag 84840

cagctcgatt tttacgggcc atatcagaag accagtctct agagaatttt tgcattatgc 84900

acactccaca tcgtcgtgtt catagccata gttagtgcag gtgttagctt catcatcgtc 84960

cttacagaac gcaacgtagc agtctacaac ttcccagaac gcttcgttga tcaaagcatt 85020

ttggtgagtt agatctaatt catcccactc ttcttcgctc tggaagtccg tatgtacgtg 85080

agcatcacaa cctacagcgc ctagagatac gacaataact aactcgtcat ctaccatttc 85140

cacgtaagcc tctgcatact cccaggcggc ttcattaaca agctgagtct ttacttcggg 85200

gctgagagct tgccactctt cttttgtata ccccagatca acgaaggtag taccaactgc 85260

aaaaccatta ttcaggataa gatatgcttg cttagtcatt atgtgatcct ctctcaattc 85320

aatataaata ttatatcaaa attttaagcg tttagcaaat aataaaaaac cccggtctcg 85380

tattgagccg gggttaggta ttattcttct acgtagtcga taaagtcttg aatagcttta 85440

ctaactactg cagagcgaag cgtggcacca ctcagaatgt gatgtgcttc ttcacgtccg 85500

ttctccacat ccaccaggac tactgcgggt acagtgcgaa ggccgaactt acgtagggaa 85560

tctacgtcgt ccgtgcgttt ttcaacgggc aggttgaact cagcggtgag cttatcaaaa 85620

acaggttcaa actgcttaca aggggcacag ttagaacctt taaggaatac aatcttctta 85680

gacattatta atactctcca atagtgtttt cattgttttt acggttgcgg tatccaggtc 85740

tagcttttct ccgaaagctt ccattacagc ttcctgatac ggctttttca gacgaccctc 85800

aggtactgct acttttttaa catctcctgc cttgactttt gccaaaatag tggttaaagt 85860

tggcatggaa agtttctggc ccccaatgtt aacgccgagc agttcggtta gcgcattgtt 85920

aaggtcaatt cgggtcattt tcttaccgtt ggacataaca ccctccgatt tcttagcaat 85980

tttcttaaac tccggtgact cacgatcccg cagagctata tttaactcgt agggagctac 86040

tttaaaatgc tcgcacatct gagtgtagaa tctgtccgac attttgtatc tcctctctcg 86100

aatttataaa tatattatac gctaaatcga gcagaaagtc aattgaattt ttcattaatc 86160

gcagtacttg cctcgtctta cgaaaaatag tgtaatggga tagactgagt acatcaacac 86220

aggagaagta agggttagga tagacgtcac cccacctgcg tacattagcg gtataaatgc 86280

tagcgttata gctaggacta tcataccgaa caacaatgcc aaggacaatg agaagcaatt 86340

ctctagacct aaccagagcc agcaaaaccc tgtccctctc tttttctcac atggacagcg 86400

aaacacacca aaaataccaa atacgaaatg taggagccat ctagcaaccc tagctaagcg 86460

tgttctgcga aaataaatgg caccgcgtat taaaatccat gatgcggaaa agaatactat 86520

accaaattga aatatcttga gtagcattat agttactaaa cttgcaaaca taatcacctc 86580

ctatttgctt gctccataca aagaagggga gcctaaaagc tccccttaat gtcacagtaa 86640

ctctacgtgt ccgccgtcgt agacaccacg ttggatttca tcacggtagt cgccagagtt 86700

gttccaatcc gctccgaaac gaacggcgat gttcatttcg tttgcggcct ttttaaatgc 86760

accgacaata gcccaaaatg cttctaagtc gttccagtca atcttaccat tgatatacgg 86820

agcgaaatca atggcctttc ccgtaacgtg cttagacttg ctagggtctt ttaaaaatga 86880

ggtgccattg gcaatattct gggcgctctg ttgtacagta cgtttgccct gaatgatggt 86940

aaaatcgtgt ggtgagagtt ccagagcacg aatagccaga gccttaagtt taggatctac 87000

agtatcgagc tgctggagac tacggtttcc aaatctgaaa ctcatattga tctccctagt 87060

gatctctgcg gtgatgcgca gatttttgcc atatagtcat taaacatgct catgtcttcg 87120

tctaatagtg ggtatttctc ccacgcgacg gcaacatatc cagcgtagat gttattaagg 87180

ttaaaatatg ggcacgtgta cacatactcg aaatttgcac tcttgaacgg tggcaaaccc 87240

gttccagacc acttcgataa acctcgtttt tcccttgcat caattgcaaa gttcagaccg 87300

tctaaatgcg ctcggtagag catagacgtc ttgtcaactg ctttgtcgga tacatcggat 87360

ttatccaact gaacgttgct ttcccaagct aggatagttt ggtaatcatt tatagcctca 87420

ggcttgtatt tgaccacgaa gacggcatca gctcgagtct gtgagaatag gatcattgcc 87480

ttctctcgtg ccacatttgg aaactctagt gtgcgttgta ctttaacatc ttgtaggacc 87540

gccgaagtag agaaagtctt taagtacgac atgacttcac tcgtattagc tataaagagg 87600

tagataacta gaccaaccag taaggttagc aaacgtttaa gaagagaagc tggatccttc 87660

gcttcttgta gtaacagcga tatcaactgt ataaatttat ccattaagaa cctcctctaa 87720

ccatttataa ttataccctt tattggagga agttgcaata aaattttata gttattgctc 87780

ggatcatact ttgggacaaa tgtcaagtag aatttagata aagaaaaagg ccagagctaa 87840

aaaagccctg gcctacttag ttttattgac ccgcagcttt acgagcttct tgctctcggt 87900

gcgcagccat acgatctaca cgttcgttga tttctttgga ggtcagccaa atatccttac 87960

caccttctat catctcagtg atctcttcta gagagaagaa cgggtagtac aggtctagca 88020

tcatatcctc aaagaatgag ttgaactgat ctgcatagtg ctggatctcg ttcttgccct 88080

taccgtagtg cgcaccacga taagtatggc ccatcaacat aacgtaaggg tgcaccaacc 88140

agccgtggca ggctaggaag attgagcagg cagctgatgc tgatggccca accagatgcc 88200

caataacggt tccctggcag ttcatgataa ggttgcacaa ctgaactgct gtatcaacgt 88260

acccgccggg actattaata taaagattaa gagtgtctcc ctcttgcata gttgccagag 88320

tgactgatag gtcgcggtag tagtctacat cgactatcgg cccatcgaga tgatagtggt 88380

aaatattata ctctgcctta gtcgccacca gggaggcgaa gtaattagga gtcttattgc 88440

cacttttctg ctctacgtta ttaatttgtc ccatattgtt accttatata aagagaatcc 88500

tctcgtcgca aaacgcgttt acatttttac ggaaattttc cagtccgtca aagttatttg 88560

tgaccacatc atcaataaac tcaggtgcaa cacctctagc ggaggcatga gtagattgga 88620

tagcgtggat gttgttaggg gcgtgaactt taagaatact agagttctgc gcaccgggga 88680

agttccgaac tagagcggct tcattatcaa aacgaacatc agaaataata ctaatgtcag 88740

ctttggtagc agtgatacga tcgaccacaa tattcaacca caagttctca tccaccagag 88800

cgcgtcctaa ctccgtgcca acaaattcta gcattttacg aggggacgtg tataatgggt 88860

acagcggggt ctcgtgaccc tgataaaagt ctggagcagt cttagcaatc agcggatata 88920

gcgctgacgc ttcaaactga ggccaaacgt aggggaaatc ggcgtacttg tcgatcccaa 88980

aacgcttcca gacgttagca gtacgctcaa gggcttcctg agtcacccaa aaccactgct 89040

taatctcttt tgtcctgcgc tctgccagct tttctggcgt gactccaagg attacagccg 89100

cgagttcgta aactggagcc gcaaaactga atttactgat agaatactcc ggaccgagga 89160

cttcccaggc ccaaacctta gccatgtcag caaaggtgtc tttgcctgcg ccggcatcac 89220

caactaatcc taaaacgtat ttcattttgt ttccttattg aacggtttgc aacggtattc 89280

attaagtgac acgcgatagg tacacgttaa tgcagtcaga ttggcaatgt aggtgtagac 89340

ctgctcatta cacttgccca ttgtgatcca atcttggtaa ggtatgcgaa catacacttt 89400

cccttcttcg tttatgaact caaaattaaa cgggcaagtc tgtaggcttg ctggccacgg 89460

taggtgttgc ggctctatcc ccgttactgt gctacttggg tctggccgtt ctgcacaccc 89520

ggatgcgatg attgcagccg agagcaggag tccatatttc cagttacgca tgaaagtctc 89580

tcctggaact cattaacttt gtcttttgcc actttggtag caagtttagg tttagcggca 89640

accacgccct ctttggctct agctgcatcc agtttattaa tacgtccatc cagatcttcc 89700

tggttcttag ctaggttggt tatgtaggta gtggtgttgc gatctcgatt tcgaatctct 89760

gtttggagat taccaattgt cttttctagt tgttcattac ggtttgatag ggactgtaaa 89820

gaactggaca tatctgttag cttattggtg atgtagtagg caccaccgaa ggtgcctgct 89880

gcaattgcca gaaacagaat tgctccagtc ttaccgctcc atattcctga aagaaacttt 89940

agcatcgaag cccttagcaa ttaaccgatc acgatcagac gtagattcgg tctttggttc 90000

cccttgaccc agcacaccga agatatagga ttctaaggtc tggtgccagc gatacaggtt 90060

tggatcaatt tcctgccacg ggaaatcttc cgcatggaag ttgaaatcag ttttaacggt 90120

aatgttaacc gttgggtctg tcttagactt tgcagcatcc catgccatcg caatgggctt 90180

gttgaaggtc tctaggaacg cagaagccgt agcagttgcg ttacgcacgt aagcgtcaat 90240

cttttcgatt gtattagttt cccaacccaa acggacggat aagccctctt cttccatcag 90300

ttcgataact ttggcaggct cgaaggtctg gaagtgatag ccaatccagg tgttaccacc 90360

gttagggcgg tatgtatggt acccgtatag ccaacgcaaa gtaccacaaa ttaataccgg 90420

acgaatctct agggttccca cctggtagac cccaaactta ccgttcttca cagtctcaaa 90480

cagattggca tagaaaatga tctgttcgaa atctgccggt acattcacaa cctgcttaat 90540

ttcttcccgg tgccaaacgc gttctgcgtc gtacatggtg ccctgcaggt catatacatc 90600

tttaacttta gagataatac gcatctttgt tctcctctca tttataaaac cattatacaa 90660

cattttaagc gagagtgcaa gtaattttta aaaaagaaaa gcccaacacc tttcgatgtc 90720

gggcttgggt agttagcgat ttaacgggtg atgttccaca cagtaatcgt taaagatctt 90780

ggctcgcttg atgctatccg gtttatactt agcgaacggg cctttcaaag ctccctgtag 90840

gatgaaaata gccttacaca gtctgccgat agtcttgcgg ctcatacagc ggagttctac 90900

ggcatgctta ccattacgaa gctctaggat cttatcgaag gacttcagga cacccgatgc 90960

atctttggca ccgccttttg cgatgatggc ctcgatatct ttacgggtgg caaactttgc 91020

caggaactcg aaggctttag ctgacagcag cttagcagag tccagaccat gattgatacc 91080

aactgccatc cacgctgata ctgccaggat aaataaagta aacattttgc ttcctcagtt 91140

tgtctttgaa ttagttaatg gtcggcgacc aactcaccac ttcgttcatc gcgggcacga 91200

ctccggatag gaacaggaag gtgactccta taacggccct accgttatac gtgtggattc 91260

atgttacaca tcatccgagt cttctctact tcccgccgtg ctttgcgacg ttgccgccgt 91320

agcttgtatt cattttcaat gaccttatgg aaatgatcat taatgttatc ttccggcaac 91380

atcaaacgaa ttgttgccaa ctgctcgatc tgaacccgaa gatgggagtt aggcatacaa 91440

agctcttgca tctccacgaa cccggataat cctagcgcgg tcatagaggc tttagcgtat 91500

actttgtcct cttttagact taactcaacg gttatccggt agcgagagtc aaacacagta 91560

caccactccg agggtactgc cccggctctt gcccagactg aataaggggc ttcctcaaaa 91620

gcgcactctt cattaatcca gtctaggatc tcttgaagtt tggggtgaag attactcatc 91680

gctatcatcc tcgtcttcta cctgacgacc atagcggtcc agtgtcacag cgggcttgcc 91740

ataggttttg ttcgtgtaga tcttagtttc cccaaaacgg gtttcagatt tacgaaactt 91800

accagcttct ttagtaatcc cattcgttgt tacacgaacc cgcccgttat cagagatctc 91860

tactttgtta cgctctgcgg ccagagatac tccagagtac atcatactga atacgatgat 91920

tgctgcaatt gaacgcttac tcatagtctt caccttcgtt atcttgttca tccacttcac 91980

cttcgaggtc tggctcgcag tcccggcaga tttcctctat ttggttctcc gccctttcaa 92040

aagcaggaca ccaccaccca caattcacgc acctaaagat ctccatatct tccgcggtct 92100

gccagaagag atcctcgata acaccttcgt gaaggttata cccgttagcc accagctctt 92160

cttcgataac attgagagct tcagtttcgc ttacacagga accttgtaca tacccgtgca 92220

ttaacgggcg gataatgctt tcaatactta gtttgctcat gaagctctcc ctatcaattt 92280

atgtaactat tatatcgaaa aatcgcctac agtgcaactg aatttttcat ttatgaactc 92340

cagctacact taggacacgg gcaggacagt gcgtgtacgc acatcttgcc gttcttatct 92400

acaccagtac catgacattt ggtacatgct gcatgtaaac acactggtcg ttgctcttca 92460

actaacttct taataaacgg agcgctttca accattttac acaattcttc gtgagagtat 92520

ccaagacctg tactaatcat tttctacctc tgcgtttcgg agtgggccag gaattagtct 92580

tgccgtgagt aacctcctgg cgggagctac gtggcataaa gttattaccg atcggatgtt 92640

cgtgttccat ttcccgagcg taggattcta actctagaaa gctggcttgg gactctcgtt 92700

ccattctttc tagatcagtg aagctgggaa atccgccgat tccgccgtag ccaataagca 92760

ttattttcgg cacttcgaca ttacgttctt ccagtcgttt acgaacaagt tctattgctt 92820

cccgagcaat tttatcgtcc attgcgttcc tccttcggta agtaatcatg cagctctaca 92880

taagagatgt tctttctttc tttatactct ggcttaccat acataccatg cacttctact 92940

actttggcgc gacgaggatt attaaacata acattccccg gtatgactac tacatcacct 93000

atctccgggg agtatttcca ataactaggt actcggtaaa catatgttct gttactgttg 93060

gagaacttaa ttccaacgtg gcgagtagtt gaagccatga tataaagcct tagccgcctg 93120

ccgcggcatg ttaagttttt cagccagttc agaccagaag tctttgccac ttaccatgtt 93180

atatgctacg atgttcccat cgaaatcttt gagacgctcg gcctctgcct ctaaagctgg 93240

tcggttcttc tcaacttcga gctgaaactc gttcagacgc atgaaattac ttttgtcgcc 93300

tagaaaacgg acgtaggctc cggctacgcc atccaccgaa gatgcaccgc atttacaggt 93360

ctgcatcttg tggtcgacca attccagggt gtcacggcag cattttacga aatatacaac 93420

tttactcata atcattatat ccttcaactg taaaccagcg tttaacttgt gtgaagctca 93480

cccaaatacc ctcatttgcg tcgctccgta ctttgtaccc tgctctacta tcatgtagtt 93540

caacgaagta gagcttaccc ggagtgaagt attgaaactt gtgaccacca acaattttat 93600

actggaggcc aactccagga gtgaagcgta agagactagc tttcaccatg tttcttctcc 93660

aggcgttttt cacgcagttc ggcttttctc ttagctacac gttcacgcag tgtgccgtgt 93720

tccttctcat aacgcaggtg atgcctgttg aaatcacgct tcatacgaac gttataccag 93780

tactcttgac tagcaatgaa gatcgccggg cgggacagtc taggaacatc gtacagctcg 93840

aacatacgag ccatttcttt atactcggca tggttcataa cacgatcgcc tggagcaatc 93900

tgattatccc aaacccactt ttcgtgatcc caatccgtat agaacgctcg gatagtgcca 93960

ggagttacct cgatttcata ccacgctgtc ttagatacac gatcgtgata cagacctggg 94020

cgattaaata ccggattacg ttctttttct cgccaattat ggaacgtacc gtctagtgct 94080

tgctcaatag tgcgtcgtgt tgctttgccc cagatgtaga aagagtcaac aaggctagaa 94140

cgaaagactc ggataccacg taaagattgc ttattcatta tttgatcccc aatgcgagaa 94200

gatggttaga cagtctatca agtgcttcca gagcagcttt gttgttttct ctcaggttgc 94260

taatagtcgt ctggaggcta tcaataacaa agtcccgaac tgctaactcc gcagcgattg 94320

cggacttact attaagtcct tccgcggtca ttgcgttgac atgtcgggta taataaccgc 94380

cagcgaaatc cagttcgtca atagcacgtt cggcgtaatg caattcatta agttcattga 94440

gttcgttcat tgattactcc ttatccatca tttcgaggcg ttctttgacg tataccagcc 94500

tgttgtgttg ttctttagct aactctgcta atctgtagat atccgccact aactgcattg 94560

tatggtcgtc cataccttcg ggtgggagtg tatctgcata tgcagtacag atagcgataa 94620

actcttctgt gttttccatt gttactttca tcttggaaac ctctctcatc aatttataaa 94680

tctattatac ggcaaaattg gcatttttgc aagtgaattt ataaagaaaa agcccctcgc 94740

tcaaagagac aaggggcttt tgtttagagg tcaggaggtg cctcagtgtt cttttctaag 94800

gatttttgtg ctctcagaac aatctggttt atttgctcca gagagtcgaa ggaaagctgc 94860

aggccatgac cttcatcggt ggcttgtatg aataaaactc tcttagaggc gtctacgaag 94920

acttgaaatt cttgttccac tttactctcc aaaaataatt acagagcact ggttttctct 94980

ggctatacga gagatgtaac cgtttacgct atgcttaata gccaagctag gttcgtcaaa 95040

catgatgcag ctgaatcgac gacctatacg gtaggtttct agcatgctat acgttgtaat 95100

tttaacatga ggttgaagct cgttatactt cttctctagg cgtgccattt cacggacacc 95160

ggatgctacg tatactgctt gaataccttt aaatactgca aactcatagg ctgtattaat 95220

agcctcgaac gtcttgccag tagctcgtcc cggattgact gatagaggcc aacgaaggtc 95280

aagttctagg aacctgacca gttggttgcg atctatgtac atgctggctc cttaaaccaa 95340

acaatgcgaa aacctgtctc gtcctctaga gcctgtacga tttgctctag tgtcagaacc 95400

ttatcggatg aaaatgtcca gagaaactgt tggagttcat cccaagactc ggcctccata 95460

atcggaacac cgatttctcg gccgaagtag tcatcagtac cacggacgtc aatacgacca 95520

ccggcgtatc gtttagcaaa cactttgcga gttagttgtc ctccctctgc aaaacgatta 95580

ggctcggtta cttccgtata cggaataccc atacgaatgt accaattgtt ggagattggc 95640

cccataaaat tggtgctata agtgatcatg atcactcctt taaactggca aaccccagga 95700

gactcgaact cctactgcac ggttttggag accggcgtgc tgtccagtaa cactcgggga 95760

ataaaattag ctaccgtggt agacagatac tgtcttacca ttctgattca taacgtaggc 95820

tacctcatct tctttcagga agatatgctg atcaagacca gcaatagaga tgctcttctg 95880

cttaggatta aacccaacgc ttgaaccatc gtgaatttct tcgccaccgt taggtgacat 95940

tactttaact gttaacattt gcttctccta tagtttgcca tctctggccg ttaagtgacg 96000

tcctggctga tatagagtcg agttccaggc agacgtcggc accccggact acattggctc 96060

tagaacagca aataatttaa gagctaaaca tactaagacg tagcgcacgt acacgatcta 96120

cgcaggcttc catctcagct aagagtgaga acactagttc tgcatcaaag gctttcattg 96180

ttgtacctct caagtagtat cgataaaatg gccttaccgg ctcccagttc cttgtttaat 96240

tccccgtaac gtcaggggac ggtcatttta ccgaatttgg agcgactagg gggaatcgaa 96300

ccccactcag taccgcttgg aaggcggacg ctgtaacccg tacagttaat cgcgaagtct 96360

tgatgaggat ttattcctcg atcggaacgt tggggtcata gaatggcagt tgggacacag 96420

tatacgtaga ttttctgggg tacagttaga ggcgaccccg tcaatatggt ctacttccgt 96480

taatactgct ccgtctactg gatgcctctc atcccaacca caagattcgc acgccgtacc 96540

cctagtctcc cagagatact ttcgtacaaa ttcttttatc tgacacgctt ttcctgtgta 96600

gccaggctct tctccggcta accactttct tactttctct ttatgctgaa atccatgctg 96660

gcaggcatta ctacaatact tacccattgt attctttttc agcggcttaa ctatgccaca 96720

attaaggcaa gtgaactctg ccattatgtc tccccaaatt ggtgcccctt gatggaatcg 96780

aaccaccgaa ggctgattac aaatcagctg ttatgccatt taactaaaga ggcaagattg 96840

gtctccccta agtgatttga acacttgacc tgacgctccc aaggcgcccg ctctgccaga 96900

ctgagctaag gggaatttgt atagttatgg gagtaggact cgaacctacc atcacctgtg 96960

cggaattacg agaccattta tttacggaat cgaaccgtat ctcaacccaa gccaggccgg 97020

cttccccatc agtcgtgccc cgtaatttgg tacccactcc cggactcgaa ccgggaaccc 97080

tgaagtctta agcctcatgc ctctaccaga ttggaccaag tgggtgttaa tcgttatcca 97140

agtaggcttc tatagcctct agggcttcca gagtagagat attgaatctc tctttaagca 97200

ctgccaccag agtttcctga ttccaggaat atactgaatt aatgtagttc tcgatgaaat 97260

tagagtagcc gcccattatt aatatacctt gattaaagtg ttatcgatgg tgttcagaaa 97320

cttaactgct gcgtctcgat tggagaatgt ctccagcacg ataatgttat tttcaggatc 97380

accgttacgt actctgatct ggtacgagac aattacttcc cagcgaaacc ataaagctcg 97440

tgggttatac cgcaaaagaa ttttttgatt cattaggtaa gccctctcat taatttatga 97500

atctattgta taataaataa gagcgtttag caaatgaatt ttagaacttt cgggaaaatg 97560

ccaccctcag tcgatgccac tgctagagac gttataggca atctatctct agctgtctgc 97620

cccattgctt tcagtgattt ctgcacgcag aaactcttct tgactggagg actttaccac 97680

gtcaaacggc cggaaatcag tggcttgttt ctccgttcat tcatcaatcg tttgtccgag 97740

tttaatcgga gaaccaacta acgaactact ttggatttgg tgcaaccggt tcgattcgaa 97800

cgaacgaccc ctggactttc aaaccagtgc tctcacctcg ctgagctaca gttgcgaaat 97860

tcatgcctgc tcctttgaat caagaagtcc accccggtct ttgggtcttt gcagtacatc 97920

acgctgctct gatgtttggt agaccgcccg agactcgaac tcggaatccc cagattaaaa 97980

atctggtgcc ctaaccaatt gggctagcga tctataattg gagcatcatg aagtattcta 98040

aacttcctta gagggtttgc aagcctctgc ctagtcactc ggccaatgat gcattgttta 98100

attagggcgc accggagttc caccgattgc taacgcttca ctgcaaccta agtcgctgtt 98160

cttaccctaa tactgtatta ctgactagga ttttcaccta gacggagtta gcaccgtagc 98220

gtgtagcggc atacctctcc aaaccgggcc acatctttca atttcggtgg cagtattcct 98280

acgcgtgcct gagttaatta aataaccctt tcagtaaaat tggcgggaga ggtgagattc 98340

gaactcacta tcattcgctt aacaggcgac cgcctatacc acttactgct tctctcccaa 98400

atatatttaa caaccaaagc gctttcgtcc atttaagcta caaggccttt atgccgcctg 98460

ttgcgtacgc gggattcgaa cccggatctc tttgattgtc aaaattggtg ggggaagatg 98520

gagtcgaacc acccgagccg caatggcaac gattttacag accgctctgc taccacttac 98580

agaatattcc cccgtatttg aagaagctct cgtgagaacc tcttcaaata cctcgtcgaa 98640

acgagatatt tgctaactta ttgtgactag ggctgaccct tgtgtccgag gatacctcta 98700

gacggtcata tctcttagcc cagagagaat ttggcgcggc taacgggatt cgaacccgtg 98760

gctccgacgt gacaggccgg tatgttgacc gctgaacacc atagccgctt aatttgttat 98820

tccggttcgt actccatcag atcatctgac tcacatgtcg gacactccca atggcattca 98880

cttaactctc cgcaatcgga acaaatgtat aacttaactt cctcttccat ttgcatttgc 98940

ttttcctctt tcgtttcaat ataaatatta tactaaattt cagggtacta ggcaaatgaa 99000

ttttttcatt aatcgtcttc ttcgtcccat gagagggagt gcatgaagat cggtagaact 99060

gtaggctcta cgtcaagcga cgggtagaag taagttttac cttgagacag atcaatgaac 99120

gtaggagttc taccctcctg catgtgttca tcaaccttgt ctagggcgtc gtttaacagt 99180

tcgaagcagt cagtattcgc tccgcaaaca acgataaaat ccattaacga cccccgttcg 99240

ggaaaccgga ggcaagcagg aagcgaacaa catcttccag cgacgggcct tcgccatctt 99300

cttcttccag atggaaaggc agaatagcat actgcatgtc agctggtgct accggggtga 99360

aggtaggctc tgcgggagct tccgccataa atactgcggt tccgtcaacc aggcggtcga 99420

tagcttcgca aacctctagc tgctcttcga tcttggcctc acgttcgcgc atcagagaca 99480

gcatctcagt gcgatactct tcgatacggc ggtctagaga ctcgatgtta ttggacaggt 99540

tatcctgtac aatcatcagg cggactacag cagaatttcc attagttggt cgtgtaaaca 99600

tgatatttcc tcgattgatt attagataaa gtcgccggta gagactacca gtttaatgct 99660

tttacggaag acttcgttca taccgtcgtg aaccattact gtcccgacca tttttggaag 99720

atagacttcc acgtcaatag ttccgtaggg catagcgtgc tcgtcagtaa gtttagtaca 99780

taactccggc tgaagctcgc agttatagaa caccatccac tcatgatcgc catcccatcc 99840

gtcccagtta agaaccagtg cggattcaat acctgttgca gtaaccttcg acatttgcta 99900

actcctctca ttaatttatg taactattat acagtaaata agagcgttta gcaaataaat 99960

ttttgaatta tccgctccga agagcggtaa tccaggcttg cagctgttaa ttgcacttgg 100020

tttgaagttg tctaagacat taactgaagg ttgatagcct tcccgtttct gcaattaaca 100080

aatcccaact tgtttttaac gtggatgctt gggtattaaa ggaaccacta cgttacacac 100140

tagggccgat tgccggaacc tagtcactaa cgctagggca atgaccgtct aagtccctag 100200

attcgccatt tatactcctg gacggcatgg agtcgattcc ctagactttt actcagcatt 100260

gcgctaaaac ctgtaaaggt aaggatgggg tattcttacg aatctgggat catccccatc 100320

agaaattaca gcttctcgga cgtttgacgg ccctgaccga agtctcactg taaattggta 100380

cttgctgctg gtttcgaacc agctaccctc gccgtgtaaa gacgatgctc tcccgattga 100440

gctaagcaag tatttggtgg tcaatagtgg actcgaacca ctgtagtctc acgtatgaag 100500

cgagtgcata aaccatctct gccaactgac cttatttggt actccgaact ggactcgaac 100560

cagtgaccta acgattatcg gtcgtttgct ctaccaactg agctatcgaa gcattattgt 100620

tcttgctgac ggacgcagat ttcctcgtcc gggtgtattt gagctattct agcatcttcc 100680

tcagcttcct tgtacgtgtc atgaaaagcc ggtgcccaaa atacgatctc ttttgtgtgg 100740

gtattaatta gcataccttg atagcgaatc atagttacct caacgtttac cgtttcgtgg 100800

tgctcctgga cgtctagcag cctctgccat tcgtttcttg actttcgcaa tattttctgg 100860

tgtttgttct ggcttgtgta agcccgccac attacaccac tgatctccgt cccaggaggt 100920

gatcaataat actccactac ctaaaacacg ttctgtgaaa gtgattcgca tcatcttctc 100980

ctagaattgg atgctccggc aagattcgaa cttgcgatct ccagcttatg agactggcga 101040

ggacggcctc tcctctacgg tgcaattggc aggggcaaca agaatcgaac ttgtgaccta 101100

aggcttcaga gacctccgct ctacctactg agctataccc caattatgcg cactctgctg 101160

agtacaacgt tgtgtctagg gccagaacat aaatgcttgc atttatggga ggcagctaga 101220

agagggatgt gacccagagg gctaacctcg tcactctcag cagagatttt atggtacacc 101280

atcgaggaat cgaacctcaa ccatagagtt cgtagctcta tattctatcc attaaactaa 101340

tggtgcagta atctggaggg atatcttgga ttcgaaccaa gatagactcg atccacaatc 101400

gaggtcatta tccagttatg ataatatccc aaataagtct tggcttatat gtgttgccac 101460

atacaataca tctacctaat tcgtcaagaa cataattcgt ataggctacg agtggtggag 101520

ttgactgtat cgtgtagagc gttagcctat ggctttcttt tcgctcacca aatttgagca 101580

ccatcgaggg ctgatcagac ctccacaaat aaaatgtaca tcgcacacat tatctggtta 101640

gacatatcta gctgcaatcc ccgcaagaaa cacagcgcaa tgctcgactg taccgatgat 101700

gctcaaattt ggcggcccta agaaactctt cccactcaca actagttgat tacttctgga 101760

ttttagccca gaaaattctc tagaaagggg caaccgttac tcgtcgggcc attgtgaatg 101820

ggctggtctc tcagccccgg ttactacttg atccttacga tctgacggca accacgtgca 101880

gcgacccttc atatattgta tagtgctcag aaggtcatta gaagcactac aactttcgtt 101940

gtttggcgga aaacgtagga cttgaaccta cataccctta cggatacatc attagcagtg 102000

atgtgtggct accaatttca ccagttttcc agttatttgg cggaagaggg gagggtcgaa 102060

ctcccaaggc gctattaacg ctcggctatt ttcaagacag atcccgtcgc cagctatcgg 102120

gttgctcttc cattaaaata agatgatgcc tcgactacac cgggctgttc aaagccccgc 102180

caggattcga acctgttaaa acagtgtttc cgccagccgt aggtttcact gatcatcaaa 102240

tttggtgggg ctagggagac tcgaactccc acgcatttaa gctacggaat ctaaagccgt 102300

attgtctacc agttccagca tagccccatt tgtttggtgg agtcacagag attcgaactc 102360

tgctgctatc ctcggtgcaa gcgaggtgtc cactcctagc agaccctgac cccaataatt 102420

tgttaaggca attaatccgg tgagcgtaat accctgagca attagccatg caaggatacc 102480

cgctcttcac aaatacgata cactctacgc ttaccaggcg tttcggagag ccactccgct 102540

attcttgcaa agcccctctt ggggtttcta ctctgcaagc gtgttttttg gtgccgactc 102600

tgtatcagat taattcctta acaaactata taaatattat atcaatttgt taagcattta 102660

gcaactgaat ttttcagtaa atttggtact cccgacgggg ttcgaacccg tgttcccact 102720

gtgaaagagt ggtgtcctaa ccagcttaga cgacaggagc attttaaatt tggcaaggga 102780

aggaggagtt gaacctaccg atctcggagt caaaggccga tgccgtaacc acttggctat 102840

tccctttcaa tataaatatt atctcaaatt ctagagcatt tagcaattga atttttcaag 102900

tattttggta gtgacccggc aacgcaggtc actatgcaaa ctactcgccg tggtctacac 102960

gaatgagcgg acaaagtttg tccttcttat agattcgcat cttctggtag atattaccga 103020

agcggagctc ttcatcgcga gcattatact ctttctgtgc cctttcgaag gatttgctct 103080

cgttccaatc ttggatccga tcctctatct tagcgcaggc ccagccgatc ccagctatcg 103140

ccagcagaat cgctactagc gtagatagtc ctgctagact taaccctaca agcatgtacc 103200

agggagtaat tcccagctca aaggtgagac ccaagaacgt agataagata cttcccatcc 103260

ccaaggagaa gagtacagca atagcagtta cgccaatctg tagcaggaaa taccacactg 103320

agtgccaaaa taggctacac aaggtgactc tgttgtcgtt cagccggtag gtgaaagacg 103380

cggaagagaa attaagccac ttgtagaaaa aacctttacg tttaatattc agcatattta 103440

gcctattact tgagttgatt gattaggaaa acttgtagcg cgataatgaa tgcggcatag 103500

gagtcagagc ctttaccacc ttcgttctca ttaacttctt ttagtagggc ttcaaaagct 103560

gctttgtgac gctcatagtg ccctctgact gtcgggccag cagcctctaa catgcctaaa 103620

aacatatagt actgggtttg taattgagcg tccattagtc ctcccacacg attttaatcg 103680

agagaagacg atttacagga atgaccagca tagtctcaga ctgtttatta aggatttcca 103740

ggatatcccc atcacgatgg agcagacgtt taggactgat atctgttact gtggactcta 103800

ggacgatacc actgtcatcc acgaaggata cgattgcgtt tttagtagac attttagtct 103860

cctgttatga aattggtggg ccaggggaga ctctaactcc cactcgttgg cttatgaggc 103920

cactgcttta actttaagct accggcccaa ggagaagggc tatttctagc ccttagttat 103980

ttatactgct gcttcatctt ccggagtgcc ttccaccgga aggttcttca gtagtggtat 104040

ccgctaccgg agtgtcttca gttggagtat cttcagccgg ctccgggtct ttcacgaagc 104100

ctgcttcttc gtcggagatt acgtacagat cctgaatgtc ttcggtattg atcatacgag 104160

ctacgctacc gtctttatag aatacggttt tggtaccttc gttgcgggcc atatttgcat 104220

caataaccag ttccgtcaga acacctttct ttaaatattc gattttaaat gccatgttat 104280

cctctacttt ctctttgatt taaagaacta ttatacaaaa tttctgacaa aattgcaaga 104340

aaaattttgt agaattaatc tcagtctgcg ccctgcgggc ttttgcccgc tgcctacaca 104400

aaattacgtg cgggcagcga taaagtggta ctccctacag gattcgaacc tgtgacccac 104460

ggtttagaag accgttgctc tatcctctga gctaagagag cattaataaa gtttaagcgt 104520

ttttacaacc agatcgtgaa cctgttcaga ataccggcca acgctcttat gcagcgactc 104580

tttaaactct agagtacgcc tggcgattag ctgtttctgt tctggtgtca gattaggtgc 104640

tggacgttca tacggaggag tatgcacaga tgccaccatt attagacctt gatagaattt 104700

ttgagacgat cacattcagc ggcgaactga acgtttaggg ttttgattac gtccgtacac 104760

tgatctattt gtttgtctag ggctttgata agtcctagct tcaccatatc gtaacagggt 104820

ttcatctcga aagtgtaatc tcgagtcagc tccccacaca gatcaaacgt aagatctcca 104880

gcgcgtagtg taaagcgctg ttgcgtacca ccgctgatga tttgtttagc cttagtcagc 104940

tcactacgac gagagaccat agactgaata tcagagcgta tcttagttaa catacttaaa 105000

tcgttcatat agacctcgtc aattagtatc tttaagaact ctcgtaaaag ctcttaaaga 105060

taccgccagt aggtaggggc cttcccctgt ttaagctatg cggcccttct gtcagacgta 105120

tcttccagtt atagtcaagg tgactaatat aaaccccaca tagtttccac agcggggcac 105180

actccaaaca ggggcacttc tagcctgtgt aagggtgcta taaatagtgg ttatgctttc 105240

gctcggggtg actccggtca tgactccatt gtcacatgct tacacagggt atacgagctt 105300

ccgcggagct gtatactcaa ccgtgtccca cttaggtctc ggagcgaccg tttgtacgaa 105360

cggttatccg aatactcttt cccacttaga gtcaggcgag atcctacctc gccaaagttc 105420

atacgatcat cgtgccgtat ttaaggacta gctttggcac ttctggagag ccatcctcca 105480

cgcggtctgt taaaatcaca cctccgaatt ttcgatgtga agttttgata gcttgaaaaa 105540

cgactcctcg tggaggaaaa acttcactat ctaggctacc gcctaaagtt cttcttttga 105600

tttgggcata tatcaggtaa gggtagccaa atcagcatcc tagtccttcg tggtttagct 105660

gtttcgttcc cgcgagtctc ccaagtcttt tcctgggagg ggaggaggta ctccagcagc 105720

gagtggttcg ccaatagaac catcagttat ctagctcttt ccgaccgcag gacttgaacc 105780

tgcatcttcc ggcagttacg ccatgataat gcccattata ctaggacggc agtgttgcta 105840

cataagtgat ttcgacaccc cactatggtg gcaataacta gcaccagacg ctatacacat 105900

gtctccaatt tgcggcctag gcaggtcagt gtgggagcta tacgagtttc tcaggctcag 105960

ctccccacct ctccggcagg ccacgcacca tgcttcattc tggtagaaca ggttaaagtg 106020

agattccacc attttctata aatcaggaga agagtttacg agactccggg acagctcccg 106080

agttttacaa gagatctcta acctacgccc gtccaatacg ctccctggcc ggtatccgga 106140

ctggatgcac gaactttgtc aggtgatcac tcttaactca ccgattctat tcaacgaatc 106200

ttaatgctcg acgagtctta cattaaaaca agttcagcgt aatcggcccg ctgttctctc 106260

taatttatga aactattata tcaacttttt aagcattagg caactgagat tttaatttat 106320

agaacacatg gttgccaatt ttacttgttc ttttgaagtc cttgtctttt gtccagtaag 106380

gtttagtatc tttactgtga aagtacaaag ctcccttcgt cggatctact ggaagatcca 106440

tatagtaaac tagtctagct atctctttag cttgtttcca ctcttcgtct ttacgatcga 106500

gtttatgttt ctttttacca acccagctga actgccctgg ttgatagact actttacaat 106560

atgtggacgg gaattttcca tagttaacac gattttttgt tacttgtgca actgcggtca 106620

ttcctttaac tccttcccct ctagcttcaa agtacacatt tttagctatg cactctatct 106680

catgcgcatc aatctttgcc tgcgcatgga agctagtgag gatggagatc attagaatgg 106740

ctgctttcat tatttctcct ttactctttg attcaagaat aatagtatat caagaaatca 106800

gccatttagt caaatcaaat tttcaatttc gattcgatag ttttaataca gtacgcttct 106860

accagggcgt caaacaccgg atcatgtttc gacggataga ccccctcagg aatcaggttg 106920

taacgctcga ttacgtcgtg tgcgtagatt tcagcacaac gtaccaatgc tttccagtct 106980

cctccgagag cctcgaaata gtcacgcggg ttacgggcgc tagagatatc ccagaatttc 107040

cacggaacga ttgcaggatc agacggagag aagacgttag cctgagccgc cactgtttcg 107100

taaatagaca tatcgaactg tgggccatta ccgtagtggc gcagggaacg agtgtcgata 107160

ccttgctcat cgataattcc ttcgattacc tgttttgcct ctacgaacgg gcagatcaga 107220

tccatgaacg tatgcttgga taccggtgac tcatgagtcg ggttgcaaac cagaacagta 107280

gactctccgt ctttagcgtt cagggcttcg ataatggaca gcgacggagc actacccgca 107340

cgagcctcat tcatccagaa tgcaatagtt ccggcggaca ccttagcacc gagggccaac 107400

tgctgggcaa cgttaggggt gcctagaacg atatacgggt ctaacgatag atctttcatt 107460

agtacgaaag cgaaagacgg catagcgata aaggtgctct tgcagtctcc cggagttccc 107520

agagattcga tatcacaaac agagatccag cggtcttgta agttttgcat attgtttcct 107580

ttgttattaa agttgcttct agatgtgtta tcacatttag aagccacctc cggtggtggc 107640

ttagtcatat cttcggacac atcccagttt tcttccatag acggccagtc agccacccaa 107700

tcttcgagtt cttcgtagca cgaatccatc agttcccggg agttgaccct agagtaatcc 107760

agggccgact tatgtgtcgc tgcacgattg aaatcgtttt tagctacaaa atttcgcatt 107820

atgccttctt agcgggtttg cgtttttgat tacgaggctt atttgccttg cccgtaaatt 107880

taatacctac gccatagcac agagcgcgaa cattctcacg gctgtattcg caaccgaaga 107940

tattcggctt gacgctaccg aaacggccct gggtcttgcg caggacttct ttggtgtctg 108000

ccttatccgg cgtactccaa ccgacgatct tggagacata gccagaggta gaacccttag 108060

ttaccggctt cttacgacgc ggggccggtt tacctacagc tgatgctgct tgagtatcag 108120

ccggatgttt acgcagatga cgctccagac gtgctttgcg attcgcttca gttttgggaa 108180

aagttgcaac tttggtttct actgcttttt tagaggtctg cttagccatg atttatttcc 108240

tttgttttga ttggtttcgt taatttatga atctattata cgttactttt tagcgtttag 108300

caactgcgtt ttttcatttt catctacaag ctcatcgaag atgatgaact cgcacctgtt 108360

accgcccgat gtgcttcgct tgctcttccg agctgatgta ctggtacccg cctttgttgt 108420

acgctggggc ggtacagagt ttctttcgct caatttcttt aagagcggct cgttctcttt 108480

cagccatctc aggatccagg atttcccgtg cctgcggtct tggtggtaga cgcgtagagg 108540

gttccccgat tttgacgctt ccagaaacgc ggcgtagaga tcgagctggt actgtggtac 108600

gtttgggaac aaatccctca aatcttgatt gattatacat ggtttcacat atcctccgta 108660

tggtaagagt cggattgcgt ttctctattg aactccctaa ctctatgctt acctttaata 108720

atggaggaca aagtcgaggg ggacacgcca aattctctgg ccattgctcg tataccatgt 108780

atagggtctc tgggcttgta tctagctctg atttctgtta cttgctcaga agtaagttta 108840

gatcttccat gattttctcc taccttagat aacccgcaat caaaggcatg tatggtgttg 108900

gccgatgcag tagaccactc taagttatct ttatgtacgt gtgctttaat accgtctttg 108960

tgatttacct caggtaaacc cagggggtta ggtataaaag cctttgctac acatacatgt 109020

actcttagat tgtgcttctt gttattagca gatatacagg tataaatata ccctcctacc 109080

ccttcttgct tatgcaagat tttgtttctt ttgatggatt tgatatctcc actttcattt 109140

ataatgtagt gatcctcgaa tccgggtaga ggtacccaat tacatgtctt caagtattgc 109200

ctcctccatg cgaacattta gcaggttatc tgcagcctca ttaccttcta caccggagtg 109260

acccttaacc ttaacgaaag ttgggatctc attgtggttt agacgatact tcttgagttc 109320

gtcgataatc cacttccact ggtctaagtt cagaggtgta tcaccgtctg ccttcttcca 109380

gcctttacgt tcccaacccc aaacccagga ctcacaacca ttcttaacgt aggttgagtc 109440

caaatagatt gtcattggtc ggccagggtt tttgttagac catagcagag cctctaggac 109500

tgcttgaagc tccatctcgt tgttagttgt gttgcgtttg ggagcagact tggtgccgat 109560

ttgctcttcg ctggagttgt aaactaccat agcccaagca ccaacattgt ctacgccacg 109620

agtattaccg cggcaaccgc catcagtata aacatgaaac attatgcgtg cccccaggaa 109680

atggtaattg attcagtatc acgttggtca aacggatgat ttacttttac ttcatagccc 109740

gcgtccttta ggtcttccat aatctgagac cgtgcggaga taggcagacc attcaatgcg 109800

taagaatcta cttttgtttt acctgaagaa gctgacccat caatatttga tataatagat 109860

ctgcgagctg ctataactgc catatcgtta gaccttttgg ctttagctgc cattgctttt 109920

gcatcagtaa aagacatatt tatttcctct ctcaaattta tgaatctatt atattagaaa 109980

ttcacgtggt ttgcaaatga atttttaata taagtggccc gaaggccacc ttagttatag 110040

taatttagct ggaggaacta gtaaattact gttatagccc agcttggctg gagggttttc 110100

ttttggcggt ttaggggcaa actgacgcat tagtgcgtcc atgcccttgt actttaccat 110160

ccctaggata acgtctatgt gtaatcctga agattgaacc agaaacttca gctgagactc 110220

ctccctttcg gagaaggtta ttttagggcg tctgttaaat aatcccataa gtcctcacgc 110280

ggtgaacgga tacgcaatag ggtcatgaga cttatacccc acgattttaa agtcgtcctt 110340

agaaacccag gtgagtacgt cctctagggt ttttatttcc gggttgatct ctagacgagg 110400

ggccgggaaa ggtttgcggt cgaattgccc atgttccatg agaaccttgt actgattctc 110460

gtagatgtgc atatttacta tacgctggtt tgctctgatt gcccggttcc ctgtgatctg 110520

ggccataagc gcaagaaacg tgtagcattg gaccatgtta aaggcttgtc ccaataggaa 110580

gtcattggat ctctggaagg agtcgagata cagatttcca ttgagtagcg agaactggtg 110640

ggtatgcatg cacggtcgta agcatccttg atcaaattcg ccagggttcc agaaggtgag 110700

aatctctccg cggtcatcaa tgcctcgtcg taaattctca tagatcttat agagttggtc 110760

aaagtgggaa ccatccggtc gaagccacgt tctgccctgt actccataga ctctacccat 110820

atcgtcggtt ccctttctgt tagggttgac cagccacgcc tcgttttcgt tggcgttagc 110880

gttccacgta ttgcagccga tagcacggaa ttgctctgcg gaatcatatc ctcgcagata 110940

tccgataagc tccatgatgg cctgaagagc atacgcttta cgagttgtga taagtgggaa 111000

tttctttccg agtacatcat attcaaagtt tgaccctatt acggttaaac aacgaacccc 111060

cgttcgaggg ttctccagcc agacaccctc ttcgagaatg cgtttgcctt cattaatata 111120

gtgaatcaca gatagactcc ttccataaca aaacgatagc gctcattttc cccagaagct 111180

acatgagtta ctacagcatc cggaggagtg gacgtaagta tcgggtgctc cagatacata 111240

atgtggtcta ggcttggtac tgtacccgcc ctaggataaa tggtggagcg ataaatcgca 111300

tccagacagc ccatagttgc tagagtttct agcagagctt tcccgccgat gcagactacc 111360

tctacttcat tacagaagtc ccggattttg gaacccaagt gggtaataaa ccgcacgtta 111420

cggggaggat tttttatcag aaccggagcc ttagaaccta ctacgtacac catggatttc 111480

ttttccagtg cttttttcag tcggggaggt gccgttgtgt aggtattatg tcccaggata 111540

acaacctgat aggtatccag gattttgtag aactgttcta gttcctcggg gatggagccc 111600

cagggaagtt ccccgtaggc atccatcgta gccggattaa aaatcccgaa ggctccatca 111660

actcgcattg cgtataaagc tgtaatcatt acaggaactc tccaaattcg tcagacagat 111720

cgtccgggtt agcctgagag gttgcaccaa cacgatagtt ggtaatctgt gcttcttgcg 111780

gagctacttg ctggttcttg gtgttcagcc aacctttcat ccagccaata ggatcttcca 111840

taattaccgg gagatcttcc ggccacggaa tgttgattgc cataaatgct aggcgtgcgt 111900

tgtaatacag gtactctacc agcaaatcgg cgttcagacc aggaatatct tcgccttccg 111960

ggaaaatata atgcgcccaa ttaatttctg tctccagaat actgcgcagg atcttcggag 112020

cattagcctg agctgctgct acaacatggg gaggaaattc tccactctgg ataatacgca 112080

gaacttccat cgccataacg gtgtggagcg cttcgtcttt tgcgataagc tgtaggttct 112140

tagcgatacc tgtcagaata tcgttctccg ccagagcaaa ggtacatgca aatgaagcaa 112200

aaaacataat ggcttctaga gcgtatacag cgtagtagaa ctccagaatc ttctgctgta 112260

cttgttcagt aagtgctaag aagtctgcct cttcggtgta ttccagagta ccttccttct 112320

cagcgatttc cagattggct ctagcgtc 112348

Claims (10)

1. The high-lytic Klebsiella pneumoniae phage is characterized in that the phage is Klebsiella pneumoniae phage (Klebsiella pneumoniae phase) RDP-KP-20007, and the preservation number is CGMCC No. 22495.

2. The Klebsiella pneumoniae phage of claim 1, wherein the Klebsiella pneumoniae (Klebsiella pneumoniae phase) RDP-KP-20007 head is icosahedral and has a three-dimensional symmetry, the head is 72.640nm, the tail of the phage is 177.797nm, and the phage belongs to the family Chinophagidae of the order Chinophagales.

3. The Klebsiella pneumoniae phage of claim 1, wherein the Klebsiella pneumoniae (Klebsiella pneumoniae phase) RDP-KP-20007 has an optimum temperature of 37 ℃ and a titer of up to 10^11 pfu/mL.

4. The Klebsiella pneumoniae bacteriophage according to claim 1, wherein the Klebsiella pneumoniae (Klebsiella pneumoniae phase) RDP-KP-20007 has a strong lytic effect on Klebsiella pneumoniae in an avian breeding environment.

5. Use of the klebsiella pneumoniae RDP-KP-20007 according to any one of claims 1 to 4 in the preparation of a medicament for the prevention and or treatment of a disease caused by klebsiella pneumoniae.

6. Use of the klebsiella pneumoniae RDP-KP-20007 according to any one of claims 1 to 4 in the preparation of a feed for preventing and or treating diseases caused by klebsiella pneumoniae.

7. A fungicidal composition for controlling Klebsiella pneumoniae comprising an effective amount of Klebsiella pneumoniae (Klebsiella pneumoniae phase) RDP-KP-20007 according to claim 1.

8. Use of a Klebsiella pneumoniae phage according to any one of claims 1 to 4, wherein Klebsiella pneumoniae (Klebsiella pneumoniae phase) RDP-KP-20007 is used as a potential therapeutic drug or health product for bacterial infection caused by Klebsiella pneumoniae.

9. An additive for preventing and/or treating diseases caused by Klebsiella pneumoniae, wherein the effective component of the additive comprises Klebsiella pneumoniae (Klebsiella pneumoniae phase) RDP-KP-20007 according to claim 1.

10. A cleaning or disinfecting agent for an avian farming environment, comprising Klebsiella pneumoniae (Klebsiella pneumoniae phase) RDP-KP-20007 according to claim 1.

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