CN113583974A - Lytic vibrio parahaemolyticus phage RDP-VP-21007 and application thereof - Google Patents
Lytic vibrio parahaemolyticus phage RDP-VP-21007 and application thereof Download PDFInfo
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- CN113583974A CN113583974A CN202110894060.2A CN202110894060A CN113583974A CN 113583974 A CN113583974 A CN 113583974A CN 202110894060 A CN202110894060 A CN 202110894060A CN 113583974 A CN113583974 A CN 113583974A
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Abstract
The invention discloses a lytic vibrio parahaemolyticus phage RDP-VP-21007 and application thereof, wherein a host is vibrio parahaemolyticus, the head of the phage is in a regular hexagon shape, the diameter of the head is about 55nm, the phage has a tail part, and the preservation number is CGMCC No.22492 through electron microscope observation. The vibrio parahaemolyticus phage RDP-VP-21007 has strong cracking effect on vibrio parahaemolyticus in water, has higher temperature tolerance and wider acid-base tolerance range, can efficiently treat vibrio parahaemolyticus diseases caused by the pathogenic bacteria in aquaculture, can be used as a disinfectant, and provides a phage source for industrialized, large-scale and programmed production of phage and treatment of aquaculture bacterial diseases caused by vibrio parahaemolyticus.
Description
Technical Field
The invention relates to the technical field of biology, in particular to a lytic vibrio parahaemolyticus bacteriophage and application thereof in vibrio parahaemolyticus infection in aquaculture.
Background
Vibrio parahaemolyticus, also known as pathogenic halophilic bacteria, is a marine pathogenic bacterium and is a zoonosis pathogen. Isolated in 1950 from an explosive food poisoning in japan. The vibrio parahaemolyticus is extremely wide in distribution and mainly distributed in seawater and aquatic products, and according to statistics, the detection rate of the vibrio parahaemolyticus in coastal seawater in east China is 47.5% -66.5%, the average bacteria carrying rate of marine fishes and shrimps is 45.6% -48.7%, and the detection rate can reach more than 90% in summer. The existence of Vibrio parahaemolyticus is found in livestock and poultry meat, salted vegetables, salted eggs, freshwater fish, and the like, in addition to marine products.
In recent years, the aquaculture industry in China is rapidly developed. With the increasing expansion of the mariculture scale and the continuous popularization of intensive culture modes, the frequent occurrence of fish and shrimp diseases poses serious threats to the healthy development of the large-scale culture of aquatic products. The pathogenic factors of aquatic animals mainly include bacteria, viruses, parasites and the like, wherein bacterial diseases are diseases with serious damage degree to the aquatic animals. At present, the main method for preventing and controlling vibrio parahemolyticus is to use antibiotics, although the antibiotics are convenient to use, have broad-spectrum bacteriostasis and quick response, the abuse of the antibiotics also causes the serious drug resistance of bacteria, and the effect in preventing and treating diseases caused by the vibrio parahemolyticus is increasingly reduced, so that the development of novel vibrio parahemolyticus resistant drugs is urgently needed.
The bacteriophage is a bacterial virus, has higher abundance in nature and strong host specificity, and cannot cause damage to the micro-ecological environment. After the phage infects host bacteria, new phage can be released during cracking, and a small amount of phage can play a role in preventing and treating. The action target of the vibrio parahaemolyticus phage is on the cell wall of prokaryotic microorganisms, and corresponding action sites do not exist on animal and plant cells, so that the use safety of the phage is improved. And the phage and the pathogenic bacteria can evolve together to prevent the occurrence of bacterial drug resistance. Therefore, the utilization of the phage to solve the biological control approach with wide prospect for bacteria.
The invention provides a safe and reliable lytic vibrio parahaemolyticus phage for treating vibrio parahaemolyticus in response to national order of comprehensive banning of resistance, solves the problems of bacterial drug resistance and antibiotic abuse, and lays a foundation for developing antibiotic substitutes for treating vibrio parahaemolyticus by expanding a phage stock library.
Disclosure of Invention
The invention aims to provide a specific lytic vibrio parahaemolyticus bacteriophage RDP-VP-21007 to replace antibiotics in the application of preventing and treating aquaculture and solve the problems that treatment is not timely due to acute disease of aquatic animals, drug taking is ineffective due to drug resistance of pathogenic bacteria and the like.
In order to achieve the purpose, the invention adopts the following technical scheme: a lytic vibrio parahaemolyticus bacteriophage RDP-VP-21007, the head of which is in a regular hexagon shape, the diameter of the head is about 56nm and the head is provided with a tail part, the bacteriophage is preserved in China general microbiological culture Collection center in 2021, 06 months and 03 days, the preservation addresses are as follows: no. 3 Xilu No. 1 Hospital, Beijing, Chaoyang, with a collection number of CGMCC No. 22492.
Preferably, the Vibrio parahaemolyticus phage (Vibrio parahaemolyticus phase) RDP-VP-21007 has a strong lytic effect on Vibrio parahaemolyticus in water.
The second purpose of the invention is to provide the application of the vibrio parahaemolyticus phage RDP-VP-21007 in the preparation of medicines for preventing and or treating diseases caused by vibrio parahaemolyticus.
The third purpose of the invention is to provide the application of the vibrio parahaemolyticus phage RDP-VP-21007 in preparing feed for preventing and or treating diseases caused by vibrio parahaemolyticus.
The fourth purpose of the invention is to provide a bactericidal composition for preventing and treating Vibrio parahaemolyticus, which comprises an effective amount of Vibrio parahaemolyticus phage (Vibrio parahaemolyticus phase) RDP-VP-21007.
The fifth object of the present invention is to provide the use of the Vibrio parahaemolyticus phage, which is achieved by using the Vibrio parahaemolyticus phage (Vibrio parahaemolyticus phase) RDP-VP-21007 as a potential therapeutic drug or health product for bacterial infection caused by Vibrio parahaemolyticus.
The sixth object of the present invention is to provide an additive for preventing and/or treating diseases caused by Vibrio parahaemolyticus, which comprises as an active ingredient the Vibrio parahaemolyticus phage (Vibrio parahaemolyticus phase) RDP-VP-21007 of the present invention.
The seventh purpose of the invention is to provide a cleaning agent or disinfectant for aquaculture environment, which comprises the Vibrio parahaemolyticus phage (Vibrio parahaemolyticus phase) RDP-VP-21007.
An eighth object of the present invention is to provide use of the Vibrio parahaemolyticus phage by using the Vibrio parahaemolyticus phage (Vibrio parahaemolyticus phase) RDP-VP-21007 as a biological bactericide.
The ninth object of the present invention is to provide the use of the Vibrio parahaemolyticus phage, which is achieved by using the Vibrio parahaemolyticus phage (Vibrio parahaemolyticus phase) RDP-VP-21007 as a medical device for treating and preventing bacterial infection caused by Vibrio parahaemolyticus.
The invention has the beneficial effects that:
(1) the invention discovers and separates a pathogenic vibrio parahaemolyticus BV-21001, and separates a vibrio parahaemolyticus bacteriophage RDP-VP-21007 by taking the pathogenic vibrio parahaemolyticus BV-21001 as a host, the bacteriophage RDP-VP-21007 has strong cracking effect on the pathogenic vibrio parahaemolyticus BV-21001 in an aquaculture environment, and provides a bacteriophage source for the industrial production of the bacteriophage for preventing and treating the pathogenic vibrio parahaemolyticus BV-21001 in the aquaculture environment;
(2) the vibrio parahaemolyticus phage RDP-VP-21007 provided by the invention is a virulent phage test phage separated from nature and does not contain virulence genes or undesirable genes; the invention does not carry out any genetic modification on the test phage;
(3) after the vibrio parahaemolyticus phage RDP-VP-21007 is added into a water body, the vibrio parahaemolyticus phage RDP-VP-21007 has an obvious cracking effect within 4 hours, has strong cracking activity and shows a good application prospect.
(4) The vibrio parahaemolyticus phage RDP-VP-21007 provided by the invention has a good application prospect in prevention and control of pathogenic vibrio parahaemolyticus of aquatic animals.
(5) The vibrio parahaemolyticus phage RDP-VP-21007 provided by the invention can be used as an effective component of various products applied to environmental disinfection.
(6) The vibrio parahaemolyticus phage RDP-VP-21007 can be used as an effective component of various products applied to environmental disinfection, for example, the vibrio parahaemolyticus phage RDP-VP-21007 can be used for disinfecting and decontaminating surfaces of water distribution systems, medical facilities, aquaculture facilities, public and private facilities or other environments in the forms of liquid soaking, spraying, combined use with aqueous carriers and the like, and can effectively control the growth and activity of target bacteria. The liquid soaking, spraying forms include but are not limited to detergents, disinfectants, detergents, etc.; the aqueous carrier includes but is not limited to phosphate buffer, LB medium, chloride free water, etc.
(7) The vibrio parahaemolyticus phage RDP-VP-21007 can effectively kill vibrio parahaemolyticus on the surface of marine products and prevent and treat the pollution of the vibrio parahaemolyticus in the preservation process of the marine products, and can be used as an effective component of various products for protecting marine products. The present invention includes, but is not limited to, the prevention of food spoilage caused by infection with Vibrio parahaemolyticus in the form of liquid immersion, spraying, use in combination with synthetic ingredients, and the like, and is particularly suitable for cooked or non-sterilizable foods. The liquid soaking and spraying forms comprise but are not limited to food degerming agents, food disinfectants, food preservatives and the like; synthetic components of the present invention include, but are not limited to, benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, calcium propionate, and the like.
(8) The vibrio parahaemolyticus phage RDP-VP-21007 of the invention can be used for preparing compositions, reagents or kits; the method can be applied to the rapid detection of the vibrio parahaemolyticus, and comprises the steps of detecting the vibrio parahaemolyticus in a target sample in the forms of test paper, a kit and the like, or screening target pathogenic bacteria in a clinical sample, so that the detection sensitivity can be effectively ensured;
(9) the vibrio parahaemolyticus phage RDP-VP-21007 can be used alone or in a mixed way, and can be used as a biological bactericide, a feed additive, or a therapeutic drug, a health product and a medical apparatus for bacterial infection caused by vibrio parahaemolyticus; the vibrio parahaemolyticus phage RDP-VP-21007 can be applied to treating or preventing infectious diseases caused by vibrio parahaemolyticus;
(10) the vibrio parahaemolyticus phage RDP-VP-21007 disclosed by the invention can be applied to industrial production, can be specifically amplified by host bacteria, can be highly purified by applying a standard virus purification method, and has a very good popularization prospect. According to the description of the invention and the common knowledge in the field, the technical personnel can prepare the vibrio parahemolyticus phage RDP-VP-21007 or the composition thereof into various products applied to the aspects of medical treatment, detection, disinfection, food protection and the like for industrial application. The product form can include, but is not limited to, the carrier carrying, the concentrated injection or the medicament soaking and the like, and the product is applied to the controlled host body surface, the oral part, the rectum, the inner pleura and other parts; as one embodiment, the carrier-borne form includes, but is not limited to, oral aqueous carriers, oral anhydrous carriers, cream formulations, and the like; concentrated injection forms include, but are not limited to, vaccine injections, pleural cavity injections, transvenous injections, etc.; dosage soaking forms include, but are not limited to, aerosols, rinses, and the like.
Drawings
The above and other features, properties and advantages of the present invention will become more apparent from the following description of the embodiments with reference to the accompanying drawings:
FIG. 1 is an electron micrograph of bacteriophage RDP-VP-21007 according to the present invention;
FIG. 2 is a graph showing the lysis curve of the bacteriophage RDP-VP-21007 of the present invention against the host bacterium BV-21001;
FIG. 3 is a schematic acid-base stability of bacteriophage RDP-VP-21007 of the present invention;
FIG. 4 is a schematic thermal stability of the bacteriophage RDP-VP-21007 of the present invention.
Detailed Description
The invention is further illustrated with reference to the following figures and examples. The following examples will assist those skilled in the art in further understanding the invention, but are not intended to limit the invention in any way. It should be noted that variations and modifications can be made by persons skilled in the art without departing from the spirit of the invention. All falling within the scope of the present invention.
The invention separates vibrio parahaemolyticus BV-21001 from the diseased sea cucumber pathological change part of Qingdao, i.e. Mo-I farm, and determines pathogenicity and drug resistance of BV-21001 through experiments, and separates a lytic vibrio parahaemolyticus phage from culture sludge by taking BV-21001 as a host, and determines the genotype of RDP-VP-21007 through a whole genome sequence.
Example 1 isolation and identification of pathogenic bacteria and phages
(1) Isolation and identification of pathogenic vibrio parahaemolyticus BV-21001
Sampling diseased sea cucumber from a diseased part, marking on a TCBS culture medium by adopting an aseptic operation method, culturing at 37 ℃ for 18-24h, and then presenting a round green colony with a neat edge on a TCBS agar plate, wherein the diameter of the round green colony is about 2-4 mm; then selecting a typical colony to streak on a Vibrio coimajiaensis color development culture medium, culturing for 18-24h at 37 ℃, then presenting a purple colony on the Vibrio coimajiaensis color development culture medium, selecting the typical colony to continuously streak and purify for 3 times, then selecting a single colony to inoculate in 5mL of 2216E liquid culture medium, culturing for 8h at 37 ℃ and 200rpm in a shaking way, and obtaining a uniform and turbid bacterial suspension. Then identified as vibrio parahaemolyticus by 16sRNA molecule identification, and one strain is named as BV-21001.
(2) Phage isolation and identification
The sewage sample for the test is collected from sewage around Qingdao, i.e. inkfarmer in 2020 and is used as a sample for phage separation.
Sample treatment: 10 ml of sewage is taken, centrifuged for 5 minutes at 10000rpm, and after larger impurities and most of bacteria are removed, the sewage is filtered and sterilized by a 0.22 micron microporous filter membrane. 3 ml of the filtrate and 3 ml of the host cell suspension were added together to 20 ml of autoclaved LB broth, and then placed in a 37 ℃ incubator overnight for culture. After the culture, 5ml of the culture solution is taken, centrifuged for 5 minutes at 10000rpm, and then filtered and sterilized by a 0.22 micron microporous filter, and the filtrate is the stock solution which is supposed to contain the phage. Then, a double-plate method is adopted to identify whether the phage exists, if the phage exists, otherwise, the phage is not separated, and new screening is needed.
And (3) purifying the phage: the plaques isolated initially are often of inconsistent size and morphology and require further purification. Picking single independent, uniform-shaped, clear and transparent plaques on a double-layer plate with plaques, soaking the single independent, uniform-shaped and clear and transparent plaques in 1ml of physiological saline for 10 minutes, taking clear liquid, filtering the clear liquid by using a 0.22 micron microporous filter, properly diluting filtrate (single plaques exist when the double-layer plate is laid), laying the filtrate on the double-layer plate together with host bacterium suspension, repeating the step for 3-4 times, and obtaining purified phage when the size, the shape and the definition of each plaque on the double-layer plate are consistent.
(3) Determination of phage titer
Spreading purified bacteriophage on double-layer plate, adding single plaque into LB broth, adding host bacteria suspension, proliferating bacteriophage, centrifuging proliferation liquid at 10000rpm for 5min, filtering with 0.22 micrometer microporous filter, and diluting filtrate by 10 times gradient to 108Taking 0.1 ml of phage diluent and 0.1 ml of host bacterial suspension in the last 3 dilutionsMl, double plates were plated and phage titer was determined. Phage titer (pfu/mL) ═ plaque number dilution factor ÷ 0.1. The result shows that the plaque has consistent shape, size and definition and has typical lytic phage characteristics. The titer of the bacteriophage can reach 1013pfu/mL or more.
(4) Preservation of phages
Phage multiplication fluid was mixed with 60% glycerol according to 1: 1, and storing in liquid nitrogen.
EXAMPLE 2 Electron microscopy of phages
Phage liquid was dropped on a paraffin plate (titer 10)10pfu/m L), placing the film-coated side of the copper mesh on the phage droplet, taking off after 10min, and naturally drying in air for 2-3 min. And then, dripping a drop of 2% phosphotungstic acid (PTA) aqueous solution on a copper net for dyeing, taking down after 10min, drying in the air for 10-15 min, observing by using an electron microscope, and selecting a clear phage image for photographing.
As can be seen from the electron micrograph shown in FIG. 1, the phage head is in the shape of a regular hexagon, the diameter of the head is about 55nm, and the phage head has a tail.
Example 3 phage genome sequencing
After enrichment culture of a single phage, centrifuging for 15 minutes at 8000g under the condition of 4 ℃, adding 10% PEG8000 and 0.5M NaCl, standing overnight, adding equal amount of chloroform, mixing uniformly, standing for layering, centrifuging for 10 minutes at 5000g, removing a chloroform layer and a PEG layer, adding restriction endonuclease for digestion treatment, suspending the phage under the condition of gradient density cesium chloride, dialyzing for 3 times by TM buffer solution at the later stage, and sending the phage to a Huada gene biological sequencing company for whole genome sequencing after 30 minutes each time. The results are shown in the sequence listing.
Example 4: experiment for optimal multiplicity of infection
According to a multiplicity of infection of 1: 1. 1: 10. 10: 1. 100, and (2) a step of: 1. 1000: 1 ratio the phage multiplication solution and the host were added to the LB broth and the total volume of the culture system was ensured to be the same. After shaking culture at 37 ℃ and 200rpm for 4-6h, centrifuging at 12000r/min at normal temperature for 5min, taking supernatant, spreading on a double-plate, and measuring the titer. The results are shown in Table 1.
TABLE 1
| Multiplicity of infection | Phage titer |
| 1:10 | 7.3×1010 |
| 1:1 | 5.8×1010 |
| 10:1 | 3.9×1010 |
| 100:1 | 5.3×1013 |
| 1000:1 | 8.6×1012 |
As can be seen from the data in Table 1, the optimal multiplicity of infection for bacteriophage RDP-VP-21007 is 100: 1.
example 5: effect of bacteriophage on growth curve of Vibrio parahaemolyticus BV-21001
The lysis curve of the phage on the host is obtained by adding the phage to the bacterial suspension, and the OD600 value is changed due to the lysis effect of the phage on the host. The host bacterial suspension cultured for 6h is inoculated into 100mL LB culture medium according to the proportion of 2 percent, phage multiplication liquid is added according to the optimal multiplicity of infection, and 3 groups of parallel controls are made by taking the control without adding phage, and the result is taken as the average value.
As can be seen from FIG. 2, the OD600 of the host without phage gradually increases with the increment of the host, and reaches the equilibrium at 6.5h, while the host with phage increases with the phage being in the adsorption and infection stage for the host in the first 1h, the OD600 increases, and with the exponential increase of the number of phage, after 1h, the phage lyses the host, the OD600 begins to decrease, but with the time being longer, the OD600 gradually fluctuates.
The vibrio parahaemolyticus phage RDP-VP-21007 is added into the host bacterium BV-21001 bacterial suspension, a certain cracking effect appears after 1h, compared with a control group, the host OD600 without the phage is obviously increased, which shows that the phage has stronger cracking capability on the host and can continuously crack the host bacterium. As the phage is in the adsorption and infection stage of the host bacteria in the first 1h, only a small part of the phage starts to crack the host, and therefore, the amount of the cracked host is far smaller than the increment of the host, the OD600 still keeps a certain rising trend in the first 1h, the number of the cracked host is larger than the multiplication speed of the host along with the exponential increase of the number of the phage, the OD600 value starts to be gradually reduced, and the mixed bacteria liquid is clearest. After continuous action for 4h, the mixed bacteria liquid turns turbid, the original sensitive bacteria are cracked by the bacteriophage, and the flora replaced by the mutant tolerant bacteria is alternated. Therefore, in order to obtain the phage with high titer, the mixed bacteria liquid should be controlled within the time range from the highest resolution to the beginning of the turbidity returning phenomenon, so as to avoid the influence on the titer of the phage.
EXAMPLE 6 determination of acid-base stability
Adjusting pH of normal saline with dilute hydrochloric acid and dilute NaOH solution to obtain buffer solution with pH of 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, and diluting bacteriophage to 5 x 10 with prepared buffer solution10pfu/mL, the dilution was incubated at 37 ℃ for 1h in a water bath, diluted 10-fold with physiological saline and plated on double plates. Counting after inverted culture at 37 ℃ for 4-6 h. The results are shown in FIG. 3.
As can be seen from FIG. 3, RDP-VP-21007 has an optimum growth pH for a neutral and alkaline environment.
Example 7 determination of thermal stability
Subpackaging the phage stock solution into EP tubes, incubating at 40 deg.C, 50 deg.C, 60 deg.C and 70 deg.C for 30min and 60min, diluting with physiological saline 10 times, spreading on double plates, and counting. The results are shown in FIG. 4.
As can be seen from FIG. 4, the activity of the phage decreased with increasing temperature and with increasing time. After the phage is acted for 60min at 70 ℃, the titer can still reach 7.7 multiplied by 10^4pfu/mL, which indicates that the phage has certain temperature tolerance.
Example 9: cracking rate test
Under the aseptic condition, 1mL of sample and 1mL of host bacterium liquid (1 × 105CFU/mL) are respectively taken, incubated for 15 minutes at 37 ℃, uniformly mixed, diluted to 10-1-10-3 gradients by using physiological saline, 100 μ L of each gradient is taken and coated on an LB agar plate, the mixture is placed at 37 ℃, cultured for 24 hours, and each gradient is repeated twice. Simultaneously, 1mL of physiological saline and 1mL of host bacterium liquid (1X 105CFU/mL) are taken as blank control, and the steps are repeated. Plates with 30-300 colonies were picked for enumeration. The test was repeated 3 times and the average was taken. The phage lysis rate was (1-number of treated colonies/number of control colonies) × 100%.
The calculation shows that the cracking rate of RDP-VP-21007 reaches 99.3%, has very good cracking effect on a host, and is suitable for being used in the culture process.
It should be noted that the specific embodiments are merely representative examples of the present invention, and it is obvious that the technical solution of the present invention is not limited to the above examples, and many variations are possible. Those skilled in the art, having the benefit of this disclosure and the benefit of this written description, will appreciate that other embodiments can be devised which do not depart from the specific details disclosed herein.
Sequence listing
<110> Ray union (Qingdao) bioengineering Co., Ltd
<120> lytic vibrio parahaemolyticus phage RDP-VP-21007 and application thereof
<160> 1
<170> SIPOSequenceListing 1.0
<210> 1
<211> 112321
<212> DNA
<213> 2 Ambystoma laterale x Ambystoma jeffersonianum
<400> 1
ccggtaaacc ggtacgtgaa ccttcaagta aagcttgaac catttcttct ggtagtgaac 60
tcggttccat ctgtgcagca cgagctagtt cttgtacttg gcgagtagtc tcagccggac 120
gtagttcgaa ctcaggatac ttaacgatac gttgctcaga tgcaaagctc caaccagtac 180
gtagaataac tgtaccttca tcgacacatt tacgcacata gcgatcaatg aaagatactt 240
tatcaatctt agtgttcagt tggttgttga gaaccaattc attcatctta gcagcatgaa 300
catcttccga agtaaccggg tcaatattga agatatccgg ggtattcaaa aatggttcag 360
agaacgatgt ataacgccat tcgttattac gtcgaataac ttttggctga attgatgaac 420
gacctgcttt ctttttctcg tcttcagact taatatgtag gttctcaagc cattcggcaa 480
cacgagcttt ctgtgcatta tgtggactgc gagccagttc cagatcatgt tgcagatcag 540
ttaaagacgg tggattcttc cactctgtct taatattttc cgtcatgggg tgtccctcat 600
taatgattaa tcgtatagga gtgtattatg tacgaaacac aagagcaatg gtataagcgt 660
atgtacgaag aaaccaaaga tccaaattac ctaaagcttt tgaagctcgt cacaaacgaa 720
gaagagaccc cgaaggatct ctctaatttc cttatgcctt ctgaataggc ttttgtttag 780
caggcggcac cttcccaaat ggatcttgct gccttgccca cttctcttga cttgaaccac 840
tcattatacc accactctat tttcacacgg tggaagcgga tactcacaat ccaaatagtt 900
tttaaataac tcttccaacg ttaaaggccc aactgctcca gtagtattta ctgtaccagc 960
acgtttgtat tgacgacgat tatccagaat ctctactagt agaatatctt ctttcaaagt 1020
gaagtcatat gaaccagaga gatctgtctg agttgaacca gacaaacccc aaagagaatc 1080
accgttagtt actggtgtaa ttcgaatctt agcattagca actgcattgc ctaaagggtc 1140
gctaagtact cctgtaattt gaaccatttc ttactcctaa acatttccaa aactaggata 1200
aatatcatag tagtttgtat caattacggg aagtctcggt gcagcctgtg gataccaagc 1260
tgtattagta ggtgccgcag tagactccgt tgctgccttc aatactccat tagcataggc 1320
taaccaagtc aaataaatga ttgtgcctaa tggtgcaccg ccttgggcct gaatgccacg 1380
aggagttaat ggggtagcat aacccgcagc aggaagtgtt gagttagcca aataagtgct 1440
gttatctggt tcaaaaatct ctaacactct gagtagtggt ctggtcgaat gaaagcgagg 1500
aactccatta gtatcataga gggccaagcc ccaatcacct gaaccaattg gtacatgttg 1560
tgccggtaca aatacataaa gatctagtgt atgggccaca cctcctgtac ttccatattc 1620
taattctaaa attgaaccac tagagatgat tgctgcatgt ttagcaaagg tacttgtatt 1680
tgtgttacta gaaataccaa acactaaagg gttccagctc atcggaatat tgaagattgg 1740
tgtactcgtc ttagtagtat ttgaaatagt aatagagaac ttgccccaat atagataagt 1800
atcctctgta ccatattgca cgtactgtcc tgcttgattg taaatctcga atccaaaagc 1860
cattatgaag ttctccgtgc ataaagcatg aacacaccac cttcagcatt tgcgttcgat 1920
gaagtattag ttgttgtata cgtcaacgtg ttacctgcta ccgatacgct atcgagatac 1980
aaagcatcgc ctgttcctcg tgagaaatca ccgaagtcat aagtgtattc aagtactccc 2040
tgtaagtcag gaattgtaat ttgatgtgtg ccaagctgca ttggaaatac ccctaacaaa 2100
ttgtaagggg cataatccac aatgatctct cggcctgctt catcataagt agctaagcca 2160
taagccatta taatctccca agtctaactc gtaagtttgc accatcatat acttcaatac 2220
gatcgcctac aatacgtagt gaaccaccag tggcttgttc cagtacttca agtgaaccac 2280
gatagatacc attattgaac tctgcgttac cattcacatc aatagcccaa cctgctgaac 2340
cagatacata gttaccagat ttgatctgaa tctgtgactg gtctgggtag atacggttct 2400
ctgtccaatc cttagcagct tgttccgcgc tatccgcagc tccatcggca tatgtcttgg 2460
cattgttctc cgcagtgttt gccttattag tagcatctgt agctgctgta ctaatagcat 2520
cactctctgc tgcatcagct ttagcctgtg cacctgctgg agtttcagca ccgatagatg 2580
aagtagttac gttactgttg tcgatactcg ctggaattga accaccaaga accaaagcat 2640
ttaagtaaca agtaccatcc cgatctacac ggaatggagc aaagtctgga tcagaagcac 2700
ctgcccagaa acgccagtat tggtaaacac ctgcactagc tgcatcatca ccattcatac 2760
cagcagtaaa tgaaccagaa cctgcaatga ttgtagttgc tgaactgatc tgattacctg 2820
taatggtatt agcaacaagt cgatcaccag agattgtacc tcgtgcaatc aagtcacctt 2880
gaataaccaa agcagggtct gaccaagtaa cagggctacc ttctggcgag ttacaacgct 2940
tcacttctga gttagtaacc aaagacgagt ctgagttatt cacgtaagtc aggtgatcat 3000
ctagtaccgg tgtacgtcca aagttattga taaaatcaat cgttgcctga gcatcactag 3060
ggaagatacc tgtaccgtta ttgatagtgt accaacctga accaggttta cctacgatgc 3120
gataaacaac actaggagag ccgggaacac catcagtgac agttcgatct tgcctccaga 3180
aatgagtatc aagctgagtg ccgccccaat cagtccagtt accatcaata gtctgagttg 3240
ggccataccg agattcttca aagattgtaa taccgtcttc accttgttct ccacgtccaa 3300
ttgggaaagg atcactccac gggccatcct gcacaccatt cacaaacact gctcgacgtt 3360
cccatttgtc agcagggtct aatactgtgt gccagttgta gataccatca atagagtatt 3420
cagagcgagt ttcaatagtc tcaccgtcat cacctacaat acggcccgga tctgaccatg 3480
ggccagcaac accatttgta acgatacgct ctctacggaa cttatcacct gacacaaatg 3540
gttcaggatg ccaagctaca ccgtcaggag agtattggta ttcaatgtag attgtatcgc 3600
ctgagtcacc gtctgaacca tcgaagcctc tgaactgata aggtagtgac catgtttgag 3660
gatcaacaac tccgttaaca ctgtagttct ctctgcgcca atagtgataa ggctgtactt 3720
cgtcttccca cgggccaagg ttactatctg agtattggta tacttggaaa atagtatcgc 3780
catcttccgg tggagtgaga tcaatcggtt gaccgttctc atcaagtagt gaaccaatct 3840
gtaactgccc attaacagtt actttgcctg tatcagtatc aacagtgagt accggactta 3900
cgtctgtctt ggatacacgg aagttatcta caatgatctc atagtcagaa gtagtaccat 3960
cgttggtatg ggttactgaa gtaacttttg aaccaatatc agatacataa gattcttccg 4020
aagagttact tagttctgtg tttttagtca cagagtttga accaaagttc agaaccaagg 4080
cttctttaat agctagggcc agttccttta acttagtaaa tgaaccagaa atagtactag 4140
ctgattcttg tcggcttact gtagtaccta cttgatctgt atcagttaga ttagctgtag 4200
cagtcgtctt agtttcaaca tcactgatct ctgtacctac atctgtatct gtagaaatag 4260
aggcagaaga tgtctcttta attgaaccag tagaagcaaa ctcttcagag taaacacgct 4320
cttggtgttg gatacgtgca gtacctgctt tcacttcatt ggttcgttgg acaccatgtt 4380
cagtacaatc ttccgagtcc caagtctgat ggatatcaac tgagtgggca tctggattgc 4440
ttacctgtac acgaaattct cgagtttttg tcagagaatc ttgaaccaaa gagttccacc 4500
aagttagcca tggttcatca atggtaacag tatctgttgt atctactcgg gttgaataca 4560
tcaagccttc ctcaagagta atactctgag gggtagattg gttcaaaagt agattaccgg 4620
ttagaaggaa ttcgtcacct tcagtattca ttacctcaag tgagtaaaag cctttgagta 4680
agtagaaatc ataggcaccg ttttcatccg tcatgaatgt tacagttgat cctttgatcg 4740
tttggtctgt gtgtaatgct gttacccgaa tagggtgatt aggcattggc acatctaagg 4800
gatcacggag tgtcccttga aaatgcacat ccatagcgtc tcctatagtg cttctaagtc 4860
agctttaaat tctgcgagtc ttactgctga ttctggagat aaacaaacgg agccatcact 4920
cagctccgtc acgttcagat tcgtcggcca agtcggtgta cttcttaccg gacttgtgca 4980
ccctgccacc gttagcaata gtggaagcag ggtcatcagc agcatctctc tttttcttac 5040
gattaattgc atttgcaatt gcctccaaga ttctgagtat gatgcctagt gttttcattt 5100
ggggtttccc ttctgatctg atttagcgtt ttccgcgccc ttatagttac cagcaatctt 5160
attcaaaatt accataaccc aatcaggaat cttctcagtc actgaaacag gtaatactgc 5220
tacaacgtga accagaagaa aagcaaccat tgctaccaaa cctaagtaag gtgcaacaac 5280
agtacctcct agcaagtccc atacgatttg aaccaattcg ttcattattt ccattcctct 5340
agtttagttt ttacgtcaaa ggatggacat gctttattag caccccaatc acgatgacct 5400
ttaatattct cttctttaat gccatataag ccagctaagt aagagatcat gtaacgtagt 5460
gcatcccatt gaacatcggt aaagttgtcc tctgggttaa gatcagagtc tacaccaccg 5520
accaaacaaa caccaatatt gtctttgtta tgaccgtaag tatgtgcgcc ttgtcgagtg 5580
actggacgac cttcttcaat tgaaccatcg cgattgataa cgtagtgata tccaatgtca 5640
ctccaaccat taccattcac gtgccaatca cggataactg cagcatttac ttttgcatcc 5700
ggttgtgtag ctgaacagtg cactgttaga tatttaggat tcatacaaac tccaataagt 5760
taaagcctcc gaagaggctt gttattataa acctagctta gcttcaatag ccgctagtct 5820
agcttctagc tcttggttct tagctttcag ctcatcgttc tcagctttta actgttgaat 5880
tgaaccaaaa gacaatgcgt gtagatcgtt accggtacga agaatagtct tcattccatc 5940
ttcacgctct ttaaccaagt gaggtagaac tttctccatc tcttgagcaa taaagccata 6000
ctcgtacttg tgaaccactt cgtcttgttc agactcctcg ttgtactcca ttacttcttt 6060
taagtaagtg tgtactggaa tctggttcac aattgaaagt gcgtcatcaa cagatttgat 6120
gtttgacttc aatcgttcat cagaagctac agtatctaca taagctttac gtgctgcatg 6180
gtttgctaat gtaggatctc ctaccaaggt taactgtact ctgaaagtag ctgaagttga 6240
acttactaca aaccactgat ttcctgccgt agataagtca ggagcaccac caatagccca 6300
acttccgtat gttttacctg cccaaatatc gctgccagcg ctacctgcat aacgaatgtt 6360
tacattagct tcaccatttg aacggtacaa gtctaattta gtagcaccag acgattctac 6420
actcaatgct tctgtattga agatagcttt agtacggtca cggtaaatac taagtgcacg 6480
tcttacaaca ttgttatcac ggatacttac atagtattca ttgttagctg acgcagcatc 6540
gtaacccatc tccgcaccat aagaaccgtt agattcaaaa caacggaaag ctgaatttac 6600
gtttggttgg tcagcataca aatccatata cattggagtt gtaccatagt aggcaatacg 6660
catttgatgc gattgtaggt aggtaaagtt taagttacca ccttcaggat agaagcgcat 6720
ggtattgcca ccttcaccta acgactgaat cttagcaccg gtgtcaccca tttgaaccat 6780
attataggca aagttagagt ctgtgcctgt cagtttaagt gcaggactga ttgagtgtcc 6840
ccacgaacca cctgctgcac cggatacttg gtatttatct gagatagaag taccactcag 6900
aataatagtg tctcccgcac ctgcatttaa ctgaacatta ccgtcatctc gtaatactac 6960
attagcgttt ccattatcat tgaaccacgt catgttctca ttgccagatg aaccaaaacc 7020
aataaaacca cgtcttgact cgtcggaatg ttgccactca aagtaagaac ttgaaccaac 7080
acctgctgca accgcatcac ggaatcggta tgcagggcca ccagagtgtt catggattac 7140
tgcacccgta ttacctacaa caaatctttt agatgcatca gccaatccta atggtcttaa 7200
ttcaatatta ttgttatcgg cagttacaaa agtacggtta tctgcgtatg catagaaacc 7260
atgctgacct cctgctcggg aaatactgaa gttattactg ccttcatact ccaccagacc 7320
actcggttga aagttgtagt aatctgtatc taaggaaaca tccataccat taggacgaat 7380
ctgaataccc gcaactgaac cactgccacc aatacgagta gaacctccac caaacatcaa 7440
cacgccctga tctgcaccaa cagattgtcg gatagtggta gtaatcacat tagtagtgaa 7500
gatcttatcg cctgagattg attgatcacc agaagtctta accacttcac cgtccaatgt 7560
gttgatctgg ttctgtagtc cagtttcaat agcatccact tgagtagttg tataagcacc 7620
tacatcagaa gcagttggct tgtactcagt agtgtataaa cgtgaccaag caccaattgt 7680
acctgtgttt aaatcagcag cacgaacatg aacctcatga ccaacagtac gagcagctaa 7740
ttgaaaaccg ccttgtgtag tctgcatatg tagtaatgat cgagtaccag ttaggccatt 7800
cacgttacta ttagataggt tcaagattcg gtgatcacca tccgcaaaca atgaatctgc 7860
atctgaaatt acagactgat ctgtggcaga aattttacta tcaatatcag cctgtaatgc 7920
aggaactaca gccaaagtgt cttggtaaga ttgttctgca ttcgctgcac tggtagctgc 7980
gttagtctca cttgtagccg cattgcttgc acttgttgct gcatttgttt cgctagtcgc 8040
ggcattggct tcagaggtag cagcctgact tgcagaagtt tgagctgcac tagcactatt 8100
agctgcatta gtctcagagt tacttgctgc aattgctgaa ccagaagcat cagaagcact 8160
taacgcagca ttagtttcac tattactagc attcgtttca gatgtagctg ccgcattagc 8220
agaagccaaa gcattagcct cagacgtggc tgcattacta gcggatgtcg cagcattcgt 8280
ttccgaagtt gctgcattag tttctgacgt tgcagcgttt gtagcacttg tagaagcact 8340
tgacgcacta gctgccgcat tggtttctga agtagaagca ttgctcgccg atgttgcagc 8400
tgcttgttca ctcgctaaag catttgcctc agaagttgca gcgttagatt cagaagtact 8460
tgcagccgca gcacttgcag cagcattcgt ctcagagatc tgtgcatcat cacgtgccgc 8520
taccgcatcg ttagccgctt gaatagcagt ctgctcaggc acatcccaag ttgcaccatt 8580
ccagaaacgt agatcgttag tagtggtgtt ccagtaggtt gcacctactt gtaacggatt 8640
accatcattg tctactgtag gatcagtcgc tttggcacct aagtattgat cgttaaagtt 8700
atcaaatgca gcctcggcat ccgcagcata accagccgca actacagcag agtttgccgc 8760
agcagattct gacgcacccg cattagcttc gcttgtagca gccgcagaag cactgttagc 8820
agcgtttgtc tctgaagtgg cagcattgga ctcactaaga gccgcagccg tctcagatgc 8880
cttagcagcg ttctcagagg caagagcatt tgcttccgat gtagcggcat tggtttcact 8940
cgttgcagca gcatttgcac tagccagaga gttagcttcc gacaaagcag cattttgctc 9000
agataatagc gcagcagcct cagacgattg ggcattagtc tcagcaagtt cagcagctac 9060
ttgagccaag agagcagcat ctcgtgcagc aacagcagtc tgtgcagctt gaaccacagt 9120
ctcttcatcg acagaaaccc agatcatttc atctgcatcg taatagtcaa gagtattctc 9180
ggttgtattc aggtagaagt tacctgactt tagtggttca ttattccatc cttcagtagg 9240
tggagcagtg aacgcaccta agtataacga aattggttca ataccttccg acacagtaat 9300
cacttcttcg atatgctcag caacaatacg tacattgtca taagcagtac cgatgtgacg 9360
gttcaccatt gaattatgtt catcacactt attcacactt ggtttagcag gcattataca 9420
aatcctcttt gttcaagttt caaattagtg ttgttgttgt agttgttaag tacattacgt 9480
cgttcgatct cttggcagta tgcttcatac ttctgcatca tttcaagtga acgggaaact 9540
gcaccggcat cattactacg cgcatacata cgtgaagcaa catagaataa aactggttca 9600
atacaataat cagggatatc aatctctgta gttgcaggat cagcatttgg ttcaatttta 9660
ggatgattgg cacggtaagt tagaaacacc gtattatcat cagccggatt aacaacctgt 9720
aatgtgcgat agttgttgag ccagtagctg tcacagttat tctcatcgtt caatggaata 9780
ggacaaccta actcatcata tacagcagta atgcccaaca catcatcaat gaaaggacgt 9840
tctggcgtat caatgatgta cttaattggt tcaagagagt tatcgttaga taacgcatag 9900
tctgaactca attcataaaa cgataacgtt tcgtacagtt gaagtgtcaa ttctcgatca 9960
cgcaatggta gtcgagtatg gatagccgtt aaagccttgt tcaagtgtga aacaatagca 10020
gggtaatctt gcgcagtgat tcctgtcatt ggttcatcaa tatccccagt aacagcaaac 10080
tgtgaaagct caccatactg gagatcttga aatagttcct gtaataaaat catgttaact 10140
cctattgatc aaaggagttt cgattataca gtgtaagagt tcattctgtc attaaggaag 10200
tcatctggtt catcccaata gtagacatcc gattgatcat cacgaaccag cataccatta 10260
gcagcaggct taaatggctt cattacagat agcattgaga tggtatccga gaagtcatcg 10320
tgcttagact taaagccgtg taccgataga agcgtaagct catccataca ttgaaccatt 10380
tctggcttct tggctaactc tttggggaac atgattttgt ggttcttaaa cataggaacc 10440
atagtgttga aacgttggaa cttattagtt acaggacgga taccctcttt gttagagtta 10500
ttgtccgaag ctaaagtgaa ccaaattcca gtattaccca ttcgctcttt gatgtaatgg 10560
atgaaaccac cttgctgacc agtaacctcg acacctactt tgattggatt gtacatttga 10620
accaatctga atagatcatc taagttgtag tccatagttt gacgacgaca gattccatct 10680
acccacatcc agtcaccgtt attattgtac gcccaaacag agataaccga gaagtcggca 10740
gactgtttat cagacgttgc aaagtcggta gtgatgtaga agttgtaggc gtgcatgtta 10800
tttagtacgt cattacggtt gtaccacacg atatcgccat catggatcaa tcggtcttct 10860
tccgacatga tctgtagcat aagttcttgg ttaaacgctt cggccttacc agacttaact 10920
gctttggtgt acatcttcat tacagcatcg taatcaaaac gatcctccca tgaacctttg 10980
aactcttcac gtgtacaagg gaatgtttct gctactggat atacgtttac gttgtaggca 11040
ccagattcaa ctgctttgta cagtggatct tttgcgttaa agggtgtccc tgaccaaatc 11100
actttacgac gttgagggtg taacgcatag tcgattgctt tgttgatcgt atcttctaca 11160
gattggatta ctgtcggtga acgtgcatcc tcatccgaga tcaagtcatc gagcaaagct 11220
agtacaggac gtgaaccatt ttcacgagta ccacgaacac cagtcttagc accgtggccc 11280
gatacaacga aagatttacc ttcaatattg ataaactccc aacggatgtc agtaagtttc 11340
attgttggta cgtacttttg caggaatgct gagttgttat agcgatactc aagtgcctta 11400
cgcattttct tcacgccgtt atccattgag tcggatacat acagtgcata aggtactcga 11460
ccaaatcccg gcagctcatt aaataccgcg agatacaaga tcaggtactc tttcagagta 11520
gacttagcaa aaccacggtg acacatgttc aatgtatcta ggccgttatc ctgtacaaag 11580
ttatcgagca ttttaaagtg tactggtgga gttttgttct cattctcacc accatctaca 11640
agcttcatga agttcacaaa ctcaagtgcg aactggctcg gcttatagtt atcaattgcc 11700
gtatagtcca cctcgttgag gtagtcttga acggttttct taatttcgtt ctctagttct 11760
tccattttag cctctaaagg ggagtttcct cccctgattt agatgagtag tagagttgat 11820
actacgatcc cagattaata agaggaatct tcaactcctc gccctttggg gtttgtaata 11880
caagatgttc ctcgttcgag tatacataca gaagtgctcc cttctttaac gagtcagcca 11940
actgtttaac ctcgctaatt tcgtcagaat gtagttgcag caatttgttt gtactctcat 12000
ttgcaagaac aacttgatcc agcttgctat taatatttgc catatttgta gctgctgtcc 12060
acacccccga agcaattgta agtaatccca ccactaacgc gacaagagta ccaaactttt 12120
ggagatcaga catatcttca ccaagttcct caccctgcta taaaaaactg aaccaataga 12180
gcgcagggat aactctaaag gaacagttct ttaattgatt ggtctgaatg cgatgagcaa 12240
atcatctaca gtaagtgtac caacgaagtc tttagcgacc tccatgtaga tgacatcacc 12300
cggattaaac agaccaaaag catttagtgt ataaccaata gatgaagtag tttgacctaa 12360
tgatcgtcca gcagcatatc gcttagttga accagtcatt acaccagatg gttcaaccat 12420
tcgaacaaac aagtggtcgg tatcagtagt actatccgaa tccaacagac cacctacgtt 12480
gatctcatag ccctgcgttt ttgaaccaat ataggtaaac gttgcactat taacatcgaa 12540
tgtccaattg ttcgaatatt caataggagc actaagtgta ttgatcagtg caagagtcca 12600
agtaacgttt tcatcagtaa cggtttgtac agcgttattg ttaccataga tgatatctac 12660
acttaggtta tctttatact gctcatactc aatacgagac acgccctcaa gccaaccacc 12720
aaagatacgt aagtatggta ggccatcagc aggagcatct actttaatag gtgaagcagt 12780
attaactgca atttggttca aaacatcaaa gtaagaaggt acaccttctt tacgagtctc 12840
aatagagaac actgcattgt ttgaaccatt tacaagaata cttagatctg catggtgtcc 12900
gtggcttaac gccactggag tgaatgcgga taaagttcca ccaggaatgg gaatccatcc 12960
tgaaccagta cctgtaccta caacgactgt agctccagca ggaatatcac cgggcacaaa 13020
cgtagtaacg tcggtattac cttcgaaatt taggggatac aggccatccc cttcaatcac 13080
ataattagcc attattgatc cctttgtaag ttttatatgc caagttccag ataacatact 13140
ctaaggtttt tagtttatgt tttggcttct cactgaaagg atcatcttta gttgcaaaat 13200
aatagccatc ttctttttca agaatgaagc gtttctcttt tagatgaata aagtgctcat 13260
aaacactttt ctccatctca gcccattcat taagtgtgaa cttattcgac atcttcaact 13320
tctccttcaa tgatcactga gtgcgctact tctttagcat tatgcattcc agattcaata 13380
gacttctgtt gtgcaatagc caagtcttgt accgcattgc gtagatcttt gagttcagag 13440
ttgtccttgt gagagatttc caattccatc ttgttagtct caggcggctt caagtgcgtt 13500
aacacactgt tcgctgcatc agatcgaacc ttctcggaat tagcattcat catcaagtct 13560
acttgaacgt tcaaagcctt ttgccttgca tcttggttca atacgtgaaa aggaaccatt 13620
gattgttccc agatcaaatt gactagcttg gacttattgt acgcatggac gtattttgca 13680
atatcagcat cagagacgcc agacgttttc cagttagtgt acttgtcagg gaaggtctta 13740
atatatgact tgatgttagt ctcaccacat aacttgtacg agacataacg cacagcatcg 13800
agataggaag ttagtttaaa cttgccttta tcgagtacat ttgtataaga caagaggttc 13860
tcacgataga tctcacgcat ctcaggatct tgaaccaatt ggttcacagt atctactagc 13920
tcttgatcta cttttcctct aatctgtcta ggcaacgctt cagacaacgt tgttactgtt 13980
agatcactca ttagtcttac cttagttgta tttggttcag atagtatatg agttatatag 14040
gagttttaaa agtgttgact gaaaagagca gatgcccaca ttgcggatgg agagattttg 14100
aaatgtgtga ttatcccttc gacagcagtg gttcaaaata ccgagcttgg tgtccgaagt 14160
gtgagaaccc ctttgaattt cgtgaaccaa ttttaacctt agaggaaacc tatgaaatca 14220
acgaaacata acactgtatt ttttgtattc ccttgtggag ccgtgataaa acgttttggt 14280
tcaatgcgag gcatgcgtat aaacggcagt agaccctact gggctgtatt ccacaaaagc 14340
tttgatcctt atctaaaggg cagactacac atgattctcc atcctatgca tggtatgaag 14400
atggagatac ctgacgagtt tgaaccatta atagataaat tcattcaacg tattaaactg 14460
tagttaagag gagccttcgg ctcctttttg cgagtgtagt cacaataatc acttatagag 14520
gtagtcatgc ctgagaaatt caatacaatt agagcttcac ctatgtctct tatagagaat 14580
caggagaaag aagagtgtct aacatattat caaaaagtaa ataaatacaa taaagaatta 14640
gcagaatacc taaatatatt aaactacgac gaaaatccca aagaaatgaa tgttctcttc 14700
gacctaatag atcctcctaa agaggacgag catcttgtca gaacactaat cgcattaagg 14760
ttgatgccat gaatgcatac caaaagatac agtgcttcga gaagacttac caagaatacc 14820
gagacttact tggacaagac gtaagtgaag aagaattgtt accccttatt aaagagcaat 14880
accctaacga tcaaagtcta gtccaatggt ggcatgataa tcatgtcaaa ctacctaagt 14940
ctccatttgc cccgatgaga cacaatggac tacttgatta aaatctactg gaaaagcacg 15000
atcacaggaa gccgatcttc tactgcctat atctcaccta agttggtgcc ccagatactg 15060
aaccacttaa agagcaacgg taaagtgcct actggattca aaaccagaga tcagccgtac 15120
aaggaaattc ctaatgaata ccaccaaact gaccccaata tcaactttat tagtcccgac 15180
ttttaaccaa aagtttgaag attatggttc ataccttgaa accaaaataa ccaacgatca 15240
ggttcgtaac atcctatcca atgaaggtta ttccagttcc atcataaatg attacatcca 15300
ctatcgagat caactagaag ctgctcgtat ggctatggaa gcttcagtga tatctggttc 15360
aatgatcata ggtaactctc ttgttgtaca tgggcctgca cctactataa aggctatgcc 15420
atgaaatcac gttacagcgt tttactaatg cacgcaaagc atcagatcga cgcacaagag 15480
aactccttca tccctattaa actattcgac atgctaattt atgaacgtgg gtttatgggt 15540
atgactcgaa tgctggatct attcgaaagt gaaccacaag cttttggaat ctttgtaatc 15600
ggactaacag gagatctcga tgaactcacg cctcagtaaa ctagtaatag ggtctcgcga 15660
atcagatgac cgaggtatgg tagcgtgcca tcaacttaca cacaaaacgt gcccttctac 15720
tttaaccaaa gaatctgtgg actgctctat atgtgcatta gacgaactaa gcaaatttaa 15780
tagcttatta ggagatctcg atgaaatgct ctagatacct aaagcttgcc gattatctag 15840
aaaatggttt aaaccgtgaa atacagggtg atcttacctt cagtaaattt gaaatggtcg 15900
gtgaacagtg gctaagtgta cgtaaacctt ccactatgaa ccagtggttc aaaatagata 15960
acctacttaa aacaatagga gagatagatg tctcgattaa atacgctgtt tgaacatgct 16020
aaagaagtaa gaaagcatgg ttcacatgga agaggttaca ttcctaacga tttatacgaa 16080
agaaagttaa ttccgggttg tagtaaaata aacatggata cctattctct tgtaaaagtc 16140
atgattgtac taatcataga ggaaggtttg aaccaatgtc tcgattagga actcttctaa 16200
cgtcaggtgc tcaacttggc cctgaataca gagatactgc tttccatttc cttggcctca 16260
aggtcgtata tgtgaagttt ggcctacctg atgaaccact tgtcctgaca accaccatat 16320
atactactaa attgatatgg gagcttaaaa aactatgtcg agattagacc taatagccaa 16380
aggagttctt agaaaccgtt ggttactcat aatgggcgag gtagatctaa gctattcaaa 16440
cgtaaatgtt tacttacctt gccaaattgc cagaaccaac gaagaacata gccgtatgat 16500
ctgccgtgta cgagcagaag tcctcgataa actcaaacca tttaaaggat atctttgaac 16560
catgtccaga ttagacatag tactgcgtaa tgctgggaga ggtagtcgcg tttgtaccta 16620
taaaccctgt ccatctacag gcacacgctc atattactgt accgattgcg cactttctta 16680
cacaaacgaa gagagtagaa aagaactctt taaggatcta ctagcatgtc acgtctagac 16740
accttcttac acaagaccaa agagcttagt cacactgatt ctgtgctgat attcgctcaa 16800
aaccgactat tcaacaatgc aaacagagat ctgttcatta gtggactgcc tttaattacc 16860
cgagctacta tgatcaagat actccgcgca ccatataagg taatgttatg tctcggctta 16920
gtagactttt agaaaatccc cttaattata agaacacctg caacgtattc gaaaaagatg 16980
agtacacctg taaggagtgt gtatgggagg atggcgtatg ctgccaaaat cctttgtatt 17040
ttagatctga cctagaggaa accgttgatg gaattaatcg acttacctga tcatctgatc 17100
actaaagtca acgtaaatga atacgaagct attcagacaa tcgttgcaga acaaaccaaa 17160
gaatactcac agatcctcga tacaaatgag gctgaagagt tgtacccaat ggttcaagaa 17220
caactaccca accttgataa acaagtagca ctagaagtac ttcgtaccat cctaccgcct 17280
atagagaatt gaaccatgtc acggatagat agtctgaacc agatggcatc cgatgcccag 17340
aataccactt cagttgagcg tcatggtgtt atctgttttg tattctttgt agtgaagggc 17400
ggctgggtag taaatgttgt gaaccaacaa ggtaacatga taggtgcact cccaattaac 17460
cgactaagag aactaactaa tgtctagact acaaactgtt atatcagctc acgcgttcta 17520
tatggttcaa cgtgaacact ttccggggcc acgcacgggg atgagtcata cccttttcaa 17580
caaacgctat ctacacacta tttttccaga gatagaaacc aatgacctga tctcaaggat 17640
agcgaatagc tacgataacc tttacttaat attggagaag ttatgtctag actagtaacc 17700
cttgaacaga agcacgatgc tagattacgt accggtggcc tttgtgacat acgctgtcct 17760
gaacaagcac aagataagac accttacctt atatttgcct atggttgtac agactgcgtt 17820
tactcttatg aaaacagaaa ccacttcaga ggaatcactg aatgtctcga ctcactatcc 17880
ttctaacaac ccgtacctat tgtaagatct ttgagagaac acgccgagag tgtacagggt 17940
gcccttggga ctctgatgta gataggtgtg aaatacccct tgttaactct aataacgtac 18000
aggaagtatt gaaatgtctc gaataactac actagaagaa caccacaaaa cctataacac 18060
aaaacgcttt gactttccta tcggcccagt cacctaccta aataactatg tggttcaaaa 18120
tacccctttt gatcgcagtg agcaaaccct cgcaagaaag aaccacgcag gagcagtatt 18180
cttcgactta ccaaacgtag tggagttgat atgtctcgat tagataaact gtatgaaggc 18240
gtgcctacct ttggtttaac actacaccgt aggtggtata aatctgtaac gatcatatac 18300
ctaaactttg aaccatctat taaactgaaa tccagtatga ggatggcatt aaaggagtta 18360
tcggaatgtc tcgactaact atattagagg cgggagtgac ccaaggagag ataaccctct 18420
acctacaacg agctactgcc aaatacaaaa caaccttcat actcaaaaac gcatttgata 18480
gtgctccctt caaaaaggtt cacgcgctat tcagagtaaa acaaggatta ctacgatgtc 18540
tcgactagat aaactactgg atgactttga ttgggcattt atgcaatcct tcatggaacc 18600
aatactagct aagtatgacc gtacagctgt aatcaattta gcaatagata ctactcgtcc 18660
tcccaaatac tcacttaaaa ggggaatact cgaatgtctc gactaagtac acttatggtt 18720
cacttcaaag gatatcgcgg tacagactct gggcctatga ctcatctaag cagaaaggta 18780
ttcaatggga actacataag cgacgtgtac cctcacatga ccatctatga taaacgccac 18840
atagttgaaa ccttccttaa actaccacga gtattggagc aaatatgtcc agactaacta 18900
ccctacttca agccagaaag gaggcagagg agacacttaa cttttcctac ataatgcgta 18960
tacgcctctt taatggtgta ggtatggtag ataagttctc ccacttccca aacatacaca 19020
taatgtacat ccgcagggca tttgtatcag cagctttcat tatactgaaa ttgaaccaga 19080
gagaaccaag atgtcacgac taaacacact ttaccaacat gcagctgatg tcacagcaga 19140
tattaaacct gtaacccaat acggtacagt tccagttgct cagtatgact tggttcggaa 19200
ccaaggaaat gggataacta gcagaatctt agtacgtagt attgaacacc taatctacga 19260
taataatttg gagaaactat gtcacggctt actcgactaa cagacccaaa tgaaccagta 19320
gtgattaatc ctaccttgga ctacccctct gtacaaagtc acccttatga agtcttatct 19380
gcatttgtgg ttcactatag cgataaagag gggtcttata ttagccgtga gatgttactc 19440
ggtacggtgt accttatagc taaaagtagg gaggaagtat gtcacgtcta gatactcttt 19500
taagctatga aagtgtggtt cacattaaaa caactctaca tgtgccttac ccttggctta 19560
gtgcagacaa gtttatgcac aatcaatatc acttctacat acaccacacg gataccacta 19620
agcatctatc ccaagatggg atacttgctc tagttttttc acttatgact tgtgaaccac 19680
ttttataggc aggtttttca gaattttcat aatttagtat gagtgtaata ctacccttct 19740
ttgtgttcgc tgagacgacc tacccccccc ccatagcagg atcactcggt aagtaatgct 19800
tcgcatctgt ccggcattaa tcaaccaacc aagaggattc aactatgtca ctattcaaag 19860
taatcgcacg cttcacatca accattgata atactctagc aatcgctgag aacatcactg 19920
ctgctggtgc taaagcttca gagtcatcca tcactctagc tgagaacttc gacctagaac 19980
agaaggctaa gctcaagcat aaacaagagc agatccaagc taacatcaag gcaggtaagt 20040
tcgacctatg attctatatc acggctatct gttcttctca attccagctc ttatcgcgta 20100
catcaaggaa gctccgtaag gggcttctag tacctaacac aacacaacac agagatagac 20160
tcatcctaag tagaaagagt tcttatagag cagcacagtt ggaattagag tgtattctat 20220
taatcttgct tgttcctcat actctctacg tgagctaccc agaactcata cctgactcat 20280
acaccaagcc atttcatgct gcttcgcagc taagcggatg caataatgta tctagaactt 20340
attaacctta ttggagaact atcatggcac aactagctaa ctcaactgaa tcaacttcac 20400
cacgtcgtaa ctctaaagag cagcaaccag ctcttgctta catcaacatc ggtaagaagc 20460
taccatcaga gacatctgaa tctggtgagt acatgcttaa tccattcttc ggtatcacag 20520
tcactgctga tgctcagaag actcgtttga ataagcaaga gaaatcactg tacgcagcag 20580
tacttgctaa gattgaagaa ctcaaagcaa atggtggtgc aggcaaatct cactcaatca 20640
acttggacat cgagctgtac attccagcag atgagccagc tgaagttgaa gcaggcaatt 20700
tcgacctgta attatcattg gtggccttcg ggtcaccttt ggcttttgaa ccacaaagat 20760
agaatgggct taaaatggat atcatctaca cttgtcagca ttgtcatgca gaatcaacca 20820
gtactatttc aggtagtgag atagaacacg gagctacata ccatcttaca tgctcatgtt 20880
gtgataaaga atcagaacta atgctagcca tttatccttt aaatgaacca caaagataga 20940
acaggaataa accatgtcta aatcacagtt aattaagcaa tacgcagcta aacacaactt 21000
agaatgtatt gatatcaaag cacctagtaa catttacgat aaactagcaa gtgtcgtaaa 21060
gagcaccaaa attgaaccaa aatggcaaat gcctgatgga ctcacaatgt tcacacgtct 21120
tactgctaaa cagcaattaa gcgatctaac tcgtgagtat atggttggac aacttaaatt 21180
aagtgcttat gaaccactat cagatgaatg gtacacaacc attgaatatc tatctgacct 21240
aggcactgac atcattgaat tgaaacaaga aattgagaga tttagctaat gtggaatgta 21300
tgttttgaac cagagtggat cagtgaagaa gagatggaaa tcattgaagc actcactcgt 21360
gaaattgaac cacaacttca agaacttagg tttgaggact agttatgaaa gtattagtag 21420
caggtggacg tgacttcacc gacacacaag taatgactga ctacatcaat gagctaatga 21480
ctaaaggcaa actacctgaa gacatcgact tagaactggt atgtggtatg gcagcaggtg 21540
cagatatcac tgcatatcat ttgtttaaaa acaatggctt agtagtacat gagtttccag 21600
ctgactggca tgacatgact gaaccatgca tacgcaaagt caacaaatat ggtgtgtaca 21660
atgcactagc aggcatgaaa cgtaacagtg aaatggcaca ggaagcagac gtgttaatag 21720
cattctggga tcgtaaatcc aaaggcacaa gagacatgat ctctcaaatg acacgtctca 21780
acaaaccaat attcatctac tactactaga gagcttcggc tctcttttag tttgaaccaa 21840
agagatagaa catggaacat ccatacgatt taaattgtta ttcagtgcct aatgaaatca 21900
tacgcttagg tgctttcgtg ctattatatg catactcacg tagattcata gatcaactac 21960
gtgatccacg tatcacctat aagaaagggt ggtatcagtt cagatatcat aagagtggta 22020
atccaatctg tattagtatt tcttgggacg gtacaaggta tagaaataca cagaagtatt 22080
accgtaagaa taggctacca aaacaagagg gactggtatg cgaactagat acattgtatg 22140
ggttaccgtg cttatctgct ccatcgctac agcagtagca tggggattta tactcgcgtc 22200
ataataagga atttgaacca tgttaaagat attcatcatc ggcttagtac tactattcat 22260
cttcacaaac ccatgggtac tgttgttccc attaaccgca ggattaatct gttttgttgt 22320
acaattattc tacatgtata tgggaaagta gaacttctta gaacttctca tccagacttc 22380
tactcatata ctaaattgaa ccaaatcact gaaccactac catatcggtg tcatactcta 22440
acagggttaa atggcacctt tatcatatcc taaaattgaa ccacaaatga tcactctcac 22500
cgacataatc ctagtcatat tgatatttgt ttacctagaa ggcttcgcct tctcttactg 22560
aattgaacca cttggagata gaaccatgaa aacattaatg cttattccac ttatcgctgt 22620
acttgctggc tgtaactcag gcgatggcaa cacttacgca agtgaaccaa aacaatgctc 22680
agactacgca actgtagtgt gggaagacaa ctcattcgaa gcattcccaa atacctgtaa 22740
tgacatcaaa gcaggaacat ttactgatgg cacactcact gagctatcaa ctgtaacaac 22800
cacattcgga tttgatacta tccagtcact ctacacagat ggtgaattcg actatgcagt 22860
tcgtactgat ctacgtgatc gcacactcaa tatctattgg agtgataaca agcaatgcta 22920
tggcccaaaa gacaacgatg taatcgtatg tgacttgagc tatgacttgg attactcaga 22980
cacactcact cgtgtaaacg atgtacttgg cctttaattg aaccagagaa taaccctatg 23040
actactcgcg tatttactcc attcttcaaa actgttggtc atgctgacca catgactact 23100
caagttatcc aagaagaaca aatgctattt ggtgctacca ttaatcacgt tttaactaac 23160
tttgataaat atcctattac ttttcatata cttaatagaa tacttatgtt ggatgacttc 23220
aaagagctga tcgttgatca agctatgctc ggctatcatc cagtcattga taccaaagta 23280
gttttactta tgcctggaat gtatccgtgt ataggtggtt ggcattgtga tggtgttatc 23340
cgtaaagacc agaactctca acctaatctc gataccctag atgaaccaat tcaacacttc 23400
atctgtacta tctcagatgc aggcgatgag cactgcggta cggatatcct tgcacgtaag 23460
gttatctacg acatcaatga tgatgagaat atttgggcac aagtgaacca gaaagtagaa 23520
atgactggtg acgtgcctat tcatactaca aagtcaggtg aaatcgtgca gtttgatcgt 23580
caaacgttac atcgtggtac agcagcaaca gtacgacaat ggcgttactt cttcagactg 23640
agcttctacc acatgccagc aatgaaccaa gatcgtaaac aagtgcaggt atactctgat 23700
atctcacaag gatggtgata tgagtagcag gctaaagaaa tttgagtaca acgctaaacg 23760
tacttatggc aataattcat tcagtatatc ggaacgtctc tgcttctgta tgggcctcaa 23820
gtatgacaat actactgtca gaggctcatt tcagctatgg aggaagcgta ttcaacctgc 23880
tactgggcta ccatcactgt caaacatagt tcagttgttc cacaaaaaac cttgggagtt 23940
aatagatgag cagactgcaa acgctttcag caaacagaaa tagagctgta ttgttccacc 24000
atgggacaca tagcgcattc atttgtgaat gtatgggtat tcatactaag gagacatttc 24060
gaacagtatt gaaaataatc cctgcaatcc gaaataagcc cagcttacta gctattttac 24120
gcaacgcgtt agaaaacagg ttatgggagg atatctatgt cgagactgag cacctatgaa 24180
gacaaactgt ccagatatga ttcaagctgt gtagcaattt gggtagatga aatatttcca 24240
aatagtgatg cttgggaaat tatagatgaa gtatctgatg cccagtgtga ggttaaagct 24300
tgcattgatt gcaactggca aaagcataac ttagcgaggt tattagatgt cctatctgaa 24360
ccaatggaat aaagaatcgt tgctgaaact aaaggaggtg atccgtgaac agcaggctaa 24420
gcaaagtgga aaagacttgg gcaaacctaa gagacagcac agaagcaaac ggctgtcttg 24480
aagcaatgag ggcatcagcc ggtatcagtt atgatgaagc acatcaattg aaccaaaagc 24540
tatgcccaac ggattacaat ccgggtatcc aatgccatac cgaatgtata tttagctgtg 24600
tcgagtacga tatagagatg atgagtaagg tgcttcgcac cttggcggtc gagtaatttt 24660
aagaataagg atttgaacca tgtcaattga acaagctaaa cagcgttttg ctaaattccg 24720
tgcgctagtt aagaaacaaa tgaagctaga acataaccat gctaagcaga acactacagc 24780
tatggtcaag gtgttcctta aaccgtttca tgctgacttt gtagaagcag cctctaaact 24840
agagcaaatg atcagagcca agaaacaatc tgattacgaa tatgtaacca aaggtggtga 24900
acaacgtgtt cgtgaagatc taaaagaagc acataatgta ctattagagt ctgatattgt 24960
ggatttgatg tatagaatcc actctgtagc atgtacaaag catgagatta ctctgcaaca 25020
ggcagtaggt agtattattg gtaacttctc agagattgag attgttacac gtaagttact 25080
agcttgtaac cttgtgcttg agtactgtcc tcacctaatc atcaacatca ctaaaggtgg 25140
tgagtatggt tatgtcggta gtctaattcg cttagacaaa gaagaggctg acctactgga 25200
tcaacactca gtagcactac catcaatcgt tccactacgc aaagtacgta acaatgctga 25260
tatcggttac cgtacattta agaagtctgc aatcatgggc ggtaagcacc atgacaaaga 25320
catctgtttg aaccacttga acaagcgtaa tgctgtaccg ttcaagatca acaaagaagt 25380
agctggtcgt atccttgcag gcaagttggg ccagttcgat cctgaaccaa agttcaataa 25440
acgtctaggt cgtatcgaga acgaagcaga agttcaagag cgtaaagacg catggcttga 25500
tcgccaaaag catatgaaga gtaaaatccg cacacttgca gaccatatat tctacttctc 25560
tcaccgtaga gataaccgtg gtcgtacata ctgtgaaggt taccacttct cataccagag 25620
cactgacgat caaaaggcaa tcatcaactt ggcgatcgaa gaacatgttg caccagattt 25680
ttagatggat acgccgtact tactacggct acccacactc acgtttacaa accttactag 25740
atgaacgagg cgatgcatgt catatcattg ccttaaacat ctttaaccga gcactatgtg 25800
cgaaccaaga aaccaagtac aagataactg gtgatattgg ttcagcagca gaagcctgct 25860
ttcattgtcc tatccaaaga gattatgaag gccataaatt agatattctc gtaagagaac 25920
ttgaatcaac taaataagga accaaaccat gtcaatgcaa cactttactc ctgcgcaatg 25980
ggcactaatc gacctagcaa ctcaatacgg taatgacaaa gatctgtatg acgatcgtct 26040
acgctttggt cgtgaaattc tcgagtccat taaagaaggc actgttgaac catggatcga 26100
agcagcagag aactcagcac tatttactaa aggtgtattc gctgtagaag agatcctaca 26160
aggcgtacca actagccatg acatcggctt agatgcagca gcatcaggcc cacagctact 26220
atctatccta cttcactgcc gtactggtat ggagaacaca ggtgcactta acactggtcg 26280
agtaccagac gtatacactc gtatctacga gaacactaca atccaaggtg taactcgtaa 26340
ggaagtaaaa gctgcggcag taccattcgc atatggttca gatgctaaac ctctacaagt 26400
attcggtgag gagaaagtag aagaattctg taaagcatat gagcgtacat tgcctgaagc 26460
atactgggca cgtcagactc tgatcaatgc gtggaaccca gaagcgctat tccatgagat 26520
cactctacct gatggttatg tagcacatat ggaatcacgt ggcctagaag aattccgtag 26580
tgagatcttc ggctaccgtt acacatacca aactactgtt aaccgtccac tgaagaaagg 26640
tgagaacaag actaaagctc tagcagctaa cgtaactcat ggctatgatg gctttgtggt 26700
tcgtgaacta gataaccgtt gtaactacaa ccaaaacatt gttcgtttcg ctatcgaagc 26760
aatcgacaac catttggagc acggttcaga gtttgaatat gaaccattcc tgcgtattca 26820
aggtcttgct ctacgcagta actttatctc tgtagctaac ctagagaaca ttcgcatgaa 26880
tggcctagaa ggtgcagacg agtcgtactt gctacgtcta cgtgagcgtg ctgtagatat 26940
gcttatgaat gaatcattcg taacttactc tattcatgat gagttcaagt gtggtttgaa 27000
ccatgttgaa cgactacgtg aagtctacaa ccaaatcatc gctgaatctt acttgtctac 27060
ttggctccta gatgtaatcg aagacctaac aggtgatcgt ttcgaatggg atgaaccaac 27120
agacatggaa atctacaacg aattgctaca gtccaactat gcaatcggtt aatacacagg 27180
ctaccttcgg gtagccttta ttttttgagg ttagtatgag cagactacaa cggatagata 27240
aattaattaa tagccctgcg aaccagattt atgagggaag tgtgcgaacc agaatgaggc 27300
attgtccaca tcaggcagag ctaatgggca gtaaaaccaa aaggtgtatc atgcttgata 27360
aatccgatat gccgtgctca ggatgtccag tagatgaaac aaaagtgttt aacgatttaa 27420
tggaggatat cttcgatgag taaattcgat acatggttag aagcagcacg tctagataaa 27480
ggattacatt tcgctgatca aagttgcttt aaccttaaaa ttgtaactag atccgatttc 27540
aatgagctat gcgccaagtc tgcaccatgc gctacatgtg ccctgtgtaa caacgtaggc 27600
atggattaca tagccttgtt agatttattg gggatacagg atgagtaggc taatcacttt 27660
actagaattc gagaaagtac cttatagctt gaagactgga tttttgtgta ataacccaca 27720
aggtgcagga gatttaaata taccttgtgc aaaagtatta gaaaagacag atatagcaat 27780
aagctgtcgt aactgtccct tagataataa agaaaaattg gttcatttct ggagaaagat 27840
agatgagcag attaaataag atgatcgaac acaataagaa ccaaggaaac atgcctaatg 27900
atccgggaag gttcaacaca tgtgcaggcc atgctaaaaa gttaattgca aattacaagg 27960
atgatgggct ttgcccattg tacggggcta tagacagccc aaattgctta aagtgtcctg 28020
cggattcttc taataaattt ttaagactaa tggtggaatt atgtcccgac tatcaagatt 28080
agtattcctt agaaagaaat atacccgttg gaatgatgca ctttgtaagg ctatgaaagt 28140
acctaatata agatttgcct gtcctaagtt tttgaaccat ttagaggaat ataacgaagt 28200
atctagaata tctctagctg tagctttaga tgatatgctc cttaaaaatg gaggaacact 28260
cgatgagtcg cttaaaaaga ttaatcgaaa tcatattaaa agaggatgaa aacagaactt 28320
actcttgtga agaacactat actggttcag atcatatagt aatttgctta catccaaaat 28380
acataacaac gttagaattt cttgaatgcg ataattgtcc catacaggag atctattttc 28440
taaataaagt attggagatt ctggatgagc agattaagca aactaattaa acagttaaaa 28500
aagaatacct tagatggcga atacccttgt gagctagtct cctacagaat aactgaagac 28560
cgatcggtta caggtacagt ctgtaatgct ccacatcgtc tgactgaggg agaaatatta 28620
tctaacgatg ccttggttag aattaaaaag gatgcctttg taccatcaaa ttgtggtatg 28680
tgtgctttag acagcaatca aatattcaac gaaaccctaa aactacttca ataaggaata 28740
acccatgtca cgcttaaaaa ctttaagaga tgaaaatgct cgcaaacgat atgaaccaaa 28800
cttctgtcgt tatactcgtg gttgtgatcc tgcattaaga ggaatgaacc aagcatgtcg 28860
aacatgtccc cacggaagaa ataacctacc taaactttgg cataaattaa gtggggtaaa 28920
tgatgagtag actcgatgta ttaaaacgca aaaagctttt acttggtgaa tatgcactag 28980
ctatccattg taaattcaaa ggctcatctt gtcctgaaca attaatggat agggcttgtg 29040
tgcattgttt tgcgaataga gacaacttac cggatatgat gaatagacta gatgaggtga 29100
tccatgagcc gaattaatac gctactcact aaacgaattg gtcattataa atattccaac 29160
agtggtgcct gttatgtaga gctagatgct caagaaggac accgtaatct ctgtaccatt 29220
cccggaacca ttacaagttg tagcagatgc ccatggcaac accggtctat cgctaatgaa 29280
ttccttcgga aagtgtttgg caaagacact ccactgctta cttatgaatt gagtgagcgt 29340
gaatcagacg agatctcata ttatgagcaa gctagacaag ctgaattcga cattgaacca 29400
acttgaggaa ttatccttta ttgatcctga tgttccagat gaatatgcaa gctgtgtatt 29460
tgataataca ttgggcttaa ctgacttccc ttattctgtt tgtcctaaag aaatagcatt 29520
gggtgtagaa atggatctaa ataactgtaa ctcatgccct gcatgttcac ctaaacgatt 29580
caacctctta gatagcgaac ttcgttcgct tttatgaaat taaccttaaa taggaaacct 29640
tattatgtca gatacaaaga aagaactacc tgattacttg aagaattcac agatttactc 29700
tctgtacctt attcttgaag caatggaacc agaaccagat gacgctgatg ataagcgtat 29760
gcagctaatc ttctctctag tagaagacgc tgaattgctt cagtgctcac ctgaagaagt 29820
actacaaggc cgtaaggctg cagctaatcc agtaggcgat atccctgttg cagtaaacac 29880
tacccacaac ccgtaattga accaaaggag ttcctcatgt ctcgtaatga agctttcgca 29940
attgtcggta taatgctagt cgtatttggt tcatttatcc tattttccaa aataggacga 30000
gagattgatt tggcaaaagc cgaattaaag ttcaaacgtg ataaagcaca tcaagaacta 30060
gtggttcaaa agattcgtga ggagcgtctg ttactcgaag caaagaacaa acagttagag 30120
cttactggtt cattcattac caaagaaggt attgtgtatg atcagcagat tgacccggtt 30180
aactgaagaa atagttgatg gtgatgttag gtataataga tctatcgttt ataaagccat 30240
taatattatg acgggtaaac ctaatgttgg tgcctgccct cacactatgt tacagactgg 30300
tttaaactgt aacggctgtt cctttacctc tgtagataaa ttcggtcaac tcttagggac 30360
attacactta tgagtaggct tcaaatttta gaaaaagaat atggtctttt aactcaacga 30420
caaataaatc gtgctcagtt atacaccaaa ttaaataagc ttaaaaaaga aggttgtctt 30480
ctacattttg taggatatcc ccaaatacct tgtcgtgaat gtattttaga cagctattcc 30540
caattcaaaa aactcttaat ttctgtagat gccgctttca gcggctctta tgaataatca 30600
accaatctca atggagaata aaatgtattt aggtcaagta gcactagtag gtgcatcagt 30660
aggcgttcct gtaggtaact gggcattagt ttacggcaca atcgtagaga tctgcccaag 30720
cgtatgccac gctgttatcc gtgtagacga tgaggaagtt gtcgttgaaa aaggtaaagt 30780
ccaactagtt gatgtgaacc tagctggttc aacactaatc gacatggacg aaagcaagcg 30840
tgcagtattc cacacattgt gggctaacta ctggattgcg ctacaagtca aagttgacgg 30900
tgtatgggaa gacattcctg aaggtatgcg tcaagttcca ttctctgaac tacaagacga 30960
tgctgaacta cgcgttaagc caagcgacga aatgcttaaa gtgaagcgtg aagaaactct 31020
acgtaagatt cacgagctaa agcaacaacg tgcagcaact aaactaatga ttgaaaagct 31080
tgttgaagcg tctaataaat ctattgacga agaacaaaaa cttcaagcta gtctagctga 31140
catcagctaa taaaccccca ctgaaccagt tagaggtatt ccattaaccg taatgcgata 31200
cgtgtaagct ctgactggtt caatcctttc gagagataga ccaatgaaaa ttcatgaacc 31260
aaactataag attacccgta cccgagatga cgatggtgaa atggtatatt ttgtacatcg 31320
ccctaatcag cgtaaagtga tgatcattaa agctggcaga cttttcaagc ctgtctcacg 31380
taaacaccct tactaccgca cactgcgtga tgcgatcatg ggagtagtga accaatgaga 31440
ttccaatgca ctgaatggtt agacggtttt accgttggtt cggtgtatca cgctgtatat 31500
caattcggta aagccgaata cagaattaat aacgatgaag gtgtcgtaga aacactaact 31560
tcacaagacg ttgctctaca ctttgaagag tgctaatgtc gaatttttgc ccgagagact 31620
cgtatgctaa atgatcgtcc tatttctgaa atcgcagaaa tcatcttcaa catggatgat 31680
tcccgtgtac agcgtgctgc tgaactaaag tctcaaggta tccttgagtt atccaaagta 31740
gaagtacgta aacgtattca agaccgtaaa ttccaacagg aattgaacca aattgagagt 31800
ggagaattgc tgcttaatca tcccattatg gataaaaagt acttcaccct gtaccgagac 31860
taagatattg tatccttgag ttgtttaact aaggaacgtc ttatgtctaa atcaaaacgc 31920
cgcgaacaag aacgtaaacc tactcgatct gagaaagctt tccgtgacta cactccggct 31980
aaacccttac agcctctgaa ccaagcccaa gctgaatata ttcatgctgt cgaatcccat 32040
ccttatatca tggctactgg ctatgcaggc acatccaaaa cctatgtacc cactcgtatt 32100
gcagccaaat ggctaaagca ggaagctatc gacaagattg ttattgtccg tcctgccgct 32160
tcgatgagtg agtcattagg cttcttcaaa ggagatcaca tccagaagat gaaaatgtgg 32220
attgccccag tacttgatac tctcaaagag gagtttaaac cgggttatct cgactatctt 32280
ctatctgaag aaattggtgc tatcgactgt gttccactag agactgctaa aggacgctct 32340
tttaaaaatg cattcatcat cattgatgaa gcagaagacc taacaattga ggaagtgaag 32400
accttgctca cccgattagg cactaattcc actatggtat ttgctggcga cattaagcaa 32460
gtagatatcg ctaaatctgg cttaggtgag ttcttagaat tacgtaagcg cagtgaacgt 32520
ttacagcgtg tagttgatca tatcgacttt gacgactacg acgacattgt tcgtagtggt 32580
gccgttaagg aagtaatcat tggacttgat gaagtagggg cataagccct atactggttc 32640
agtctattaa ccctaattag gagaatataa tggttacgcc aatccctgta gacaaagccg 32700
tgtttgacct tattcagaca cgtaagcaag aaatcaacaa gtatcatgaa gactatttga 32760
aagctctccg tgaacttgaa gtaacagcca ctgtaaccgg tggtactgta gtaggtgatg 32820
tgccagccgc accaccatca ctataaaatt gaaccaataa tacaaagctc cttcgggagc 32880
ttttttcgtt tctggagtaa acaaaatgac caaatttcgt cgtaatgatc gagtgatcgt 32940
aagtaaccct tccttcatct gctacaagcg tgttggtaat atcgaagagt ttaattcaaa 33000
cggtacacct cttgtacgct ttgaagatga caattcatca atgcatatcc gtactgaaaa 33060
ccttgactac ttcaatggtg gttcaaatga taagtacctg ctgtggcaac ctgagtctaa 33120
ccgtccacca caagtaactt atggttcata cggtcaagcc cttaaagtgg ctaaagacat 33180
ggcccaacgt caccgtaaga agttcattat ctgtaaactt gatactgaag tagaactatc 33240
cgactttgta ataaaaaagt tgtaagcgag gaaccagatg tcaaaactac aatggcacgt 33300
tcgcctatgg tcatcaatag cgatgctgat tctgatcgtt tatctatccg taaacgcttt 33360
gctaaattac tcgatagatg gctacacgat aattcgaagc attgatttag catttatcac 33420
tatcatggct atgttgaaca tcattgttga tgacatctgg cccatggctg acaaatatcc 33480
aaagagtgaa ccaaaaaatg aataagcgag tcgtttatga gaacgccact gctaatccta 33540
aagtggtctt ttacacggtg ggagactcaa cggatgagtg taatcagagg gttgaaccaa 33600
aaggaaagat caagctacgc acagatctgg ccttcaacct aatcaaaacg gagactgtag 33660
actaatgcct tacgttatcc tacttactgc tatttggttc attgccgcat gggtgaacca 33720
cctacttgtc tgcttcaatg aagaagcatg gggattcttg attgctggtg caatcttctt 33780
cccaatcggt gttgcccacg gcacttggtc gtggttctaa cgtagaggcg ttccgcctct 33840
ttcatgaatt tgaaccaaac taaaggaatt ccaaagtgaa tctaagcaaa gcaaacccat 33900
ttaaaattgg tgcaatcgct atcagtagtg ttgtagcact atggttagca ctgaacgtgt 33960
ggactatcgt accggctggt cacgtaaaag tacctgtctt attcggtaaa gtttccgacg 34020
atgtacttga agaaggtttt aacattcctg ttaacccatt cacgtcattc gatacaatca 34080
gcattcgtac tgataaatac gaaatcaccg gcctgaatat cccaacacaa gaccgtttca 34140
actctactgg taacgttaca gttatctacg atattaacgc agataaagcg agctacattc 34200
gtaaagagtt cggtaacatt gatcaattta ttgataaaac tttacgccag caactacgtt 34260
actgtctctc tagccacaat ccatactcta caacatcaaa accatacttg caagcaataa 34320
attgaaatct ttctgtatta actttatcaa gggtatcttg aaaattaaaa tatggtccaa 34380
cgattccgtc aaatgggttc ctccctaacc aattgaaagc ttcttctttt gtcatatctt 34440
tagtttggtc atgacaacac ttgcatggaa tgtaaccaga ttggtagaat ggactgtctt 34500
tcatgtaagt tggtgctaat tctcccttga acagtgttcg atcaacaaaa tcatcaacac 34560
aacattgtgg ataacgtaaa tattctcccc aaacacggta aagtttttcg tggtaagtca 34620
tattattctc cattaaatgt ctccctagtt cggtcacgtt cttcgttaac atcgagaaga 34680
cctttcatca caagaacacc ttgaacataa cctaaccaac ggtgtgattt tgtttctgag 34740
gatagtttgt ccatataaat ctcattacac atccaatata gatgattaag gttggttggg 34800
tcatctggtg tatatttgac aatagaatcc caatcttcat caagaccgaa catgttcatg 34860
taatgtgctg ccaccctttg ataacttttc atcttttcct cctaatcaat tcaatttgtg 34920
taatcatacc accttgacac gctgtgtcaa atataaattt aaattatttt ctgctattga 34980
taaacattct tgttcgtgtt aagattttta ttgatgttat gcatctggct gcgatatata 35040
ctcattctga aagttttagg gttcttgtca gagtgaaggg aattggagtt gtaaacaaca 35100
tcctaagaaa ctcagccata gatttgattc tcaaaagaca aggtaatata gaattacatt 35160
cttgtcaaca taagtttgac cactttaagt atctgctctt taacaatttg gtgttgtctc 35220
ataggaatat gtaattaacg ttacaacctc cctgttacag cttagtctat agtatactac 35280
gataactacg ttatcaaata gacactctca taagcttagt cgcttatata gaggaatact 35340
tactaaagac acattctctc atgatggact agtatgatct aatatacacc ttgtctttga 35400
gtttgaaatg aaaagtagcg aagccaaaac cctcaagcgc gaagcgctta ttaaaaggtg 35460
tatttaaaat acatgtttaa aagatgttga acaatcccta tagtttcagt atcttactcc 35520
aacctccggt cattaatttg gtcggaggtt tttctttatc tctaatttat actccactcc 35580
gtgtatcttc ctcttatacg cttaaaagta tattctctaa caaaactaaa atttcttgtt 35640
gacatcacaa tctgtcatgc taagattcaa ttacctaaac aagcaagagg aaattttatg 35700
cataaatata ttttagttga caggagtagt aattccatta aagactacgc agttatcgtg 35760
ctagatactg ttgaaggaga agacaattac acttggaacc tttctgttac ggataatcta 35820
caggatgcta catcgtttaa tagtccagaa caagctgttg gtatgctgaa tcttgtctgt 35880
aaccaacctg aaaattggtc agttgatatt tacacggagg agaaataata tgaacctgtt 35940
tatcactcta tatacactaa ttggtgtgtt cgtaattggt acggtaatcg taaacttacc 36000
actagataac accttcacca aattccagaa atgttgtatg gttttgtttc ctatccacac 36060
aactattatc ttcgttattt cttggattag ttattctttc gctagttaca atgaaaagaa 36120
aagtaaactt tgccaatgtg atggttgcaa gatgagtcgt gacccaaatc aaggatatca 36180
accttgtcac aattataatc ttgatggagg tgagaaatga tttggttctt ggttaaatat 36240
tgcacattat cattcttact tattattggt atagtctaca tcaatgttga ttggtggaac 36300
gaagactcac gaagatcgac tttattattg ctttcttggg cagcaagtca cggattagct 36360
acagtatctt atctggaaag aggtgattgg ttaacttgga gtaataaatc atgaatataa 36420
tcacttggtt caaaataaag attcttagta aagtagtgtt tgttgatggt aaacctatag 36480
attgtcatgg attacgtttc aaaggtggac tacccttcga cgaaggaaca gagtattaca 36540
ttgataaaac tgcttgggaa ggatgggatt attttggaga aggtgtatat tgcacaccaa 36600
aaggttttaa gtgtgatttg aaaaatcctt actatattca taaactgaac aaaacattcg 36660
ctaagtttgg aaaggagatg aaaaatgaat ttagaccctg aacacattaa agtttcactc 36720
gtccaagctg atcatgagca aaacttaggt caatgcagac ctactctggt gttgtaattt 36780
accacgaacc tacaaaaatt atggtgagtt gtactaaaca caaatctcaa tggaagaata 36840
aatgtgaagc aatggaaatg ctagaatcta aactcaccga atctatagat aaagttaatc 36900
ttatgcttat tactagtaaa cttgacgaac taaaatcttc tcttggtaga tacaaaggtt 36960
tgacattgga agattatgat attctttacg gaaatgttga ggaaatccaa tacttacttt 37020
cggaggttac agatgaaaat acaaccaatc tataaaatcg ttaatcaaat caaagatgaa 37080
ctcaaagctt ggaatgttac gattgaactg aacacagatt tgtttgagga aggtggtgtt 37140
gaagtagaag aaacaaattt cagaatcgtt atcttttgtg aacatatcaa agaccctgtt 37200
caaatatcta ttccagttga agatattgac gattatgatt tagaaaatac tttgcaaatg 37260
ttgaagtttg agcttgacaa ttatgttgaa gatgataatc tctattatca caacgtttca 37320
ttacgattac attaggagga tttatgtctt tattacttgg ttggatattg tggagagatc 37380
atgtaaaaac tttcggtaag aacaaaccta tcgatggctc gttttatgtt ataatacttt 37440
tctgtttaca agcagatgct gtattgttag ctatattact caaacaataa taggagaata 37500
atcatgacaa tgttaaaact ttcagaaaac ttagaagtaa ttgacctaga ttcgtcctct 37560
aagatgcctg tgggtcattt tgtacgtaca tctgatacat cgttcaggtt tgttcgtaaa 37620
cctttcacag cagccataca agacgtttct gcacaagaac aattgtgttg gatccaacga 37680
gaattagagg gttagtagat gtcggtattt attattagaa ataaagacac tctagaacag 37740
tgggttgctt caagtggtaa acgttcttgg aacaaaagta accatgctaa ggctgctttt 37800
gctaatagct ctggtatgac aaaacgtgat cctttgttaa aagagttcgt tgccaagctg 37860
tccagatatg aatctttgaa atttaacaat caagatattt acgaagttgt agaattacac 37920
tctgatgcag aaaaacgtgc agctagaaat gaacgtattc ttaaagagat tattgaaacg 37980
ttttatggta aaggttattc tattggtaat ggtcaatact tagagatgtt agatagaatt 38040
ttcgatgata ataattggtt tattgaggat taaaggatgt tgaaaactga aaagaggaaa 38100
ttaagagtta aatactctcc aacaaagtgg cttattgatg cattagttga aaacaatgat 38160
gacttcattg aagatttaac gaaaaattta atgttgaatg agttattgtg cggagagtgt 38220
gatccaaaac aattcttgat tgatacaatg tatcataccc tcaatcagaa acagattcag 38280
gttgtagagc gaagacttag tcagttgaaa ggggatagta atggttaaac aatttcacga 38340
tacaccacct cggccttgca agtatcctgc tgaatgtaca tggatagata gccgtggaag 38400
gattagagat gaagaaacag ggagaggtat tgatttatct gccccttata gtggagcacc 38460
aataatccat ccaccttggc ctaaaagatc aaaagaacag caataccttg ataagatttg 38520
tgaattacaa aagaaagttg acaagtttcc ttggtatgaa ttaggttgtg ggtttgcaat 38580
agggagtttg ttctggggga ttatgtttac attgtttgga ggcactcaat gaaagataat 38640
atacatctaa ttatcccttt tatccttctt attattgtgg tagttcttgt attctttgat 38700
gtagtctaca aacgtaaaga gaaagaatct aaattaaaag aggatattaa taaactcata 38760
aaggattttg aggaatcaaa gaatgactaa agattacata acagtgaaac tttcttatga 38820
caaagaagat cttattgatg aagaaacgtt gattgaatat tacaatggtg atattgtaga 38880
gtatcttaaa tcacttctga aagatgaagg taagcatgaa ttcatcgatt ggtttgaaat 38940
tgaaagcatg gaggaagtgg atgaataaaa agacaacaca tgaattagca agagaattgc 39000
ttgaattaga agatgtacct gttgtgcatg tttacaatca ttgggataac tttgatgaca 39060
atcctatgac gtatgtgagc acttttggtc tgaacctctt gcaagatgat gatggtaatt 39120
tgattgaagt tggtttattt ccagaagaat taatttacag tgaaggattt ggtaatgatg 39180
aagaagagta agtttatagg ttggaataat ccatatactt tcagttttga tatggatact 39240
catttacaag agatacaacg aaagaggtgc gatttcttaa atgaggttga tcaagctatt 39300
aaagactact ttatgttcaa atacaacacc gatttaaatg aaattgaacg tattaagaat 39360
aacgtaaata actttaaact gaatagtcgg tttcaaaagg ttgttcaact atcatcagga 39420
caagatagtt attatgatgg tgagttctta ttcttgacag tggtaaacca ccctctcaag 39480
ggaaacttga ttattcgaca tggttggggt aaggaggaag agtgattgat tgggaaaagt 39540
ttaacaacat tataagtggg ttacctttta aacttacaga cgagcaatac gatttccttg 39600
tgaaatttat taatggtgaa gggcatttct cgttgatcgg agatgctggg gttggtaaat 39660
ccacaataat gctagtgtta aagttgtatt ataaccacga acttataggt tgcggtacta 39720
ctggtgttgc tgcagtaaat ctacctaatg aaatgggtat cggtacagca cactcagtat 39780
ttaatatggc tcgtgacatt gctatagaaa gtgattggaa aaagagacca cacgatgtac 39840
tgagtacgag tgaccttgtg aaggtaattg ttattgatga agtatttaat catagtgcac 39900
aagagttagc cttttatctt catcaggtta ataagatgaa tagagctaca aggaaacgta 39960
aagctagaaa catcagactt ctacttgttg gcgatccact tcaaaatatc cctataacct 40020
ccaatgaaca gaagaaactg tacacagagc tttatggaag ttattttatg ttcaatacaa 40080
ccttatggaa agatgctaat attaaaactt atgtactaac agaggtgaaa cgtcaggttg 40140
gttcagaacc aaaggatatg tggttcaaga aggctttaca agttgtaagg ttcggttata 40200
cacaacatta tcagaaagtt tgtgaaggat taaatcgtaa atgggttggt gacaaccaca 40260
gtgatgatgc agtttatatt gctccaacaa atgcaatggt taataattac aatgatagat 40320
acctctcaat aaatcaaaac cataagatga cgtttgaagt ggagtttgat aaaaagtaca 40380
ataagaaatc ttttcctatg gagtgggagg taactctagc tgtgggttgt aaggttataa 40440
cgcttgttaa taatcctgaa ttaggttacc agaatggtac agtgttaact ttaacacaat 40500
tatcatcaga aggtgtttat ggtgtgaagg attcaggaga ggaaatattt gtccctatcc 40560
atgaattcaa agaggatgag gtttatgttt ctgatgaaac caaagatggt gttattaggc 40620
aagtacaaaa gagacgacat gtagctagtg cttatatgtt acctgtcaaa ttatgcgccg 40680
cattttcgtg caaccgcgta caaggacgaa ctttcaactt cgaaactgtt gttgattttg 40740
gttctgacag acaagcttgg ttatacaaca aagaaggtat ggaagatttc atgacaggag 40800
gggcatttgt ttcgttgagc cgtgtaacaa atattaactt tttgaaatta aagaataaaa 40860
tataccctca tcatataaaa gtttgtgaag aaagtaagaa gttttggttt agatccttgg 40920
aggaaatgaa gaattatgag taaatttgaa gaccttatag ggattaggtt tggtaggtta 40980
gttgtgatag agaaaataaa atctaggaat aagtctggaa ggagtgttat taaatggaaa 41040
tgtaagtgtg attgtggagg agagtcttta acagtaactc aaaacctaaa cagcggtcat 41100
acagtttcgt gtggttgtta taacaaagag cagacttcaa aagcaaaaac taaacacgga 41160
ttgcatggga caagatctta tacctcatgg tgtagtatga aaactagatg taacaatcct 41220
aatgcagata attataaata ttacggtggt agaggtatag gcatttgtga tggatggtat 41280
gattttcaga acttttataa cgatatggga gattgcccag aaggacatta tatagaaagg 41340
gtcgataata atggtgatta cgaaccaagt aactgtgtat gggcaactat ggtagatcaa 41400
ggtaagaata gaagagataa ttccaataat acttctggta gtaggggtgt gtattggcat 41460
tcacgtgatg agaagtggca agcatttata ggcttcaata atattcaaat ctatcttgga 41520
agctttaatt ccaaggatga cgctataaaa tctagaaaac aggcagagca cctttattgg 41580
gaagatcaac gtaaacgtgt tgaagattgg gtgaataagc aatgacaaaa ccaaacaaaa 41640
tttctcgtga tttcgcacaa gaagtatttg acttagttaa gtcagaggag tatacttcac 41700
tttatcaact ggatgcgaag ttgctcgatg aaattacata ttggcatcca caaattataa 41760
ttgaaatttc agaatattta gctcggagga aataattatg gacaacaata tctacatcac 41820
cttgaatgat ggtaaatatg aatacatttt taattcaaaa gaaggaacgc aaactattaa 41880
acgtaatggt caaccttggc gtgatgaaac aggtgataac cttctacttg cgatggcgca 41940
acgtattgat caattagaag aagaggtgta tcaacttgaa tgtgatgcaa tgggagatga 42000
cttataatgg aaacaatcac gcttcttgac atcattaaac gatgtcgaac aatgaataca 42060
attcgcacac aagagttgaa atcaacaaca gattttgata cattacagac attatattca 42120
gcttatgtta atgtttctat ggaaactctt acgcgaggat atacaggttg tacaatgaga 42180
tacaaagatt tttatgataa agttttgaat aaatttgagg agatgaattg atggatactg 42240
aatacaatat tattacaggt gttgaggtga aagtggatgt atatgctggt gagaattgtg 42300
atcaacatga accttactta gaatcttggt gtgaagggga tatggactca gacaccagta 42360
aagagtttaa acttgattca aaacgatggc ctgtaggcac aaaattaatt gtccaagtac 42420
cgatgtgtcc taatccagaa tgttatgttg atgctgattt ccaagatgaa aacggtaaat 42480
gtacagaatg tggttttgat tgggtggact gggctgaacg taaatattct taaaataacc 42540
ttgttgacac acctttcttt ttctgataat atctaagaat acagtgatta gccttagaga 42600
tagagatatg aaatgtgata aatgtgaaaa agatttgaat gaacttgaga ttgaattaga 42660
ttcaaaaact tgttttgcat gtcttgacaa acaatacgaa gattgcgaca atgataatac 42720
agatgattgg cagaaagatt taatctggga ataatcattg aaagaattag ccttaggatc 42780
gttatagtta tggcgtaggc gtgtgagagc tggctcgact cacagatgta acaggaaagt 42840
gtcgctacca gaatgttatg ttaatagagc ttttatttta gtatgtaaaa tcttccgtta 42900
gctcaattgg atagagcaag atgtttctac cgtctaggtt ctgagttcga gtctcaggcg 42960
gaaggctttg catactaagt tctttttgta atgtgccgtt agctcagagg cagagcaaag 43020
tgctcataac acttaggtca ggatttcgaa actcctacgg cgcaccacaa agagaattat 43080
aagcaatact taaatcgtga gatcacgagc ctttaatggt ggggatgttt ataccttatt 43140
aagagtagag gtttaaacat atgagaagta atttaaaaaa ttttccagat tattactacg 43200
atgtaggctc aaagcttatg tataatataa caaattctaa gtatatcaaa gcacagtgtc 43260
gtgaaggaag atcaccctca tggaagatga agaatagtgt tactggttgg ggtagtttcg 43320
gggaaaaaca ggtattgagg gcgctgcacg attatttgga gagtccttta atagaagaac 43380
cttgtcttat aaaacgctca gagtataaaa catttcgagt tagaggcaaa ttagtacatg 43440
gggtaggtat caacgattat caaggccctg tgatcgttga taggaaggca atcccttcat 43500
atgcagcttg gtctgatatg ttaagaagga gttattgcga acagagacaa gaacaaaaac 43560
cctacctaat aggtaatagt gtgtgcgaag agtggttaac tttctctgaa tttaagaact 43620
ggtatgatga gaggtatttt attggttgtc aattagataa agatttaaag gtagaaggga 43680
ataagcatta ttctcctgac aactgcactc ttgtccctag gaaattaaat ctcttattca 43740
gaaatacatc acaagaaaac aagagacata ttataatttc tggtaacaga tactcagtta 43800
gatttaaaat aaataataag atatatacaa gtggtacctc ctatgaggat cttgatgatg 43860
cctgtagtgt aagggacctt attaaatcta ttgtatatat tgaatatctc agaagtttaa 43920
taggatgtta tacttcttat gtagataacc ttttattaat cataataaat agactcacca 43980
tcttaataga agaaaatgaa aaacttatac ctttaatcaa aaataaagat gtccttaata 44040
tttacaccgt gtacgtaaac caagtgtaag tcacagatag ctcggacagt ttcgacatcc 44100
taagtgtagt gtaaatacat gagtcctgtg gaacttggat accaccgaaa aagggtttgt 44160
agtaggtgaa tgcacttaaa atagtgtaag tgataacgag aaaccctgcg agaaattatt 44220
ctcaataccc attaagatcg tctctagtca tcactgtaaa acaacaatac ctagctaagg 44280
tagaaacgta agagtggaaa cttacactga tgcaagtcag ttagttgaga atcccgtagt 44340
attgaccaca gactgcgtta tcagggttaa gtggtgttcg tcggaaacga tactgtagcc 44400
gtaaggcaag ttaggagtaa acttccttaa aagttagatg gacgcatcga caacaaaacc 44460
cttcattcat atacttcatt gtgtcactgt ttggagggtt tatactttta acacgagaca 44520
atagagatat tgctcattaa caataacata aataggagac tattatgcta acacaatttg 44580
aacgtgaaat gtttgatctt ttcaactttg gttttaacac agataaaggc tgttcattta 44640
caaatacatc ttcattcttt ccaccttatg ctatcaagaa gtttaagtgt gataaatatg 44700
taattgaact tgcattagct ggttataaga aagaagattt agaggttaag ctagagaaaa 44760
atattcttac aattaagggt aaaccttctg atccaaaaga acacggctat gaagatacac 44820
ttgaatctac aatcaaacgt agcaagttta ctcgatcatt cactttgcag aaaggagttg 44880
aagtttgcac aagtgaattt aaggatggtt tgttgaagat tcatttgaat aagtttgttc 44940
cagaagaaga gttacctaaa acaatcagta ttaaataaac aggaaacaat tatgttcaca 45000
attaaactat tctacgataa ctacagttac aatgttttat cagcaccaca ctacaatatc 45060
tatagaaata cagaaacagg tgtgacagag attactttgt ataaagacca cacttctcag 45120
aatggaatca cttataaagt gagtggtaaa cctttacaag ttccacactg ggattacgct 45180
tttattgaga actcttctgg taagacgatt gatcatattc gatgataacc gataaatata 45240
agttcattaa gagcctcgca catttgtgcg aggttttgtc gtttatagct atagcaagtg 45300
tgtgatggag aagaattctt gtttatgata taattagtgt attgatagaa agagggttac 45360
acttatgtgg aacgtaatag tgggaggaat tacctctctt gtttctggtt ggtttgaaac 45420
taagaaacaa aaacaacaag ctaaagcaga ttatgagaaa gctcaactag aatctgtaag 45480
tagttatgat atccaagcac agaagaatat gcaaacgtct tggaaagatg aatatttaat 45540
tttactacat actttaccaa tatggggtta tgttatccca agtgaaactt tacataagag 45600
tttagacaca ctttggttga agcttgaaac agctccagat tattggtggt tgatttatat 45660
tggtatggtt gtatcaacat tcggtttacg ttggatgatc caaggcaaga atgtgatgag 45720
tattagaaaa ggtaatggag gtaaataatg gctagaggaa gaggtgctcc ttcaaaagag 45780
caagccctca aaaataaaga agaacgtgcg aaagctaaga tcattgagca gaagattaaa 45840
agtaaggaat tactagcaga ctcataccac gaatatatgg aaacacttca caaagtggcg 45900
acagatactt taggtaaaga ggtctcaatt actaaccaag tatcaacttt gaaattcctg 45960
attggattag cagatgaagt attaaaagaa gaagctaaga aaggtaatag tgaatcagaa 46020
acagaaaaac ctgcagaacc tcaagcaaaa gcaaatggaa ctacaggtga ggtaatttct 46080
cttatttcga caaactatga tgacgaggat taatcctacg gattagaata attatcactc 46140
aggttattga cattaatatg acaaactgtt aatattaaaa gataacgatg tcgaaacaca 46200
ttaagtgttc attttaaaat ttgtattttc tcctccagcg actaagctga gttggtattg 46260
tgttccctcc ttacacagta ttgattcagt tagtcgcttt ctttttgttt attttctata 46320
agctaaccat tcaataatag gtggtaatat aatagcacct acccacaaga acactataac 46380
ctctccgatt gtgaacattc ttattcctct ttaataaagg ttttagccac ttcaatgtgg 46440
tggtgaaaac cttgtggttg ttcagtctta gctagacgat aatttaactc ttcggaaaca 46500
tcaaccatca ttttcaacat agtcttacat tctttaagtt cacgtttagc taagtctagt 46560
tcaaaagcat tattacaatc actgcagtat aaatcctttt ctgtgataat cttttcgaac 46620
gtacgtgtaa catagtactc tgcgccacac tgacatgtat ctttatacca taaacctact 46680
ttatctccaa cttttaacat tatattactc cttctcttta agttacacac atcttagcaa 46740
acgcactgta gttgtcaaca aatattttat ataatttcaa tgttgacatt gaaaggaggg 46800
tgtgtcatga ttggtgtaga ttttattgag gagggataaa tatgaagact ctaataatac 46860
ttattttatt tatattatgg aacttagcgt ggtatatgat tcaaagagaa gcggggttag 46920
tttaagatga ctaaagatta ttcacaatac ataacacatc tggtgtattc accaaagagt 46980
agtttgttcg aattaagttt atcaaacgat acatatttta tcggagataa agctaaatct 47040
ttgatagagt ggttgtggtt ggataaaggt gagcctcaag ctttcagacc catcgagatt 47100
gcaagagcta caagaagtga tagaaagtca agattagtga caaccctaac agacgatgaa 47160
ctaaagcaaa agcttaaaga tgtcatggaa atcgtagcta aaaatcatca cgttgatatt 47220
cacagcttca acttcaacag ttttatggat tgtcattctt tatatgctta tgttgatgtg 47280
gattctcctg ttatggtaga tcttaacttt gcattagcag ataagataag tcttgatgag 47340
aatgaagatt tgtgtaattt taaatatgtt gggatttttg attataagag tgaggaggaa 47400
taatatatga agaaattcag tgaccaagaa agacctaaag gtgtttgtta tgattgtaaa 47460
ttaccttata gtagttttgt tgatatgatt atatctgatg aagattggga gaaaattaac 47520
cctactcacc accaaggtgc aggtttatta tgtcctacgt gtattagtaa tcgactaaac 47580
acaataggtg agtggtataa ttataaactg gttaaagagg tttgagatga aaagtttcaa 47640
agaaaaacgt agaaagttaa aagaaagatt atctaagttg acacaagagg agttacttaa 47700
ggagttacag tcttatgaag ctaaagtgcc actagctgta gagtattgtg aatgtaaggt 47760
taagcgtcta accgcgatag gtttatatga tcagttacct tcaccaactt caacagaagt 47820
tgttgtgaga aaaggttacg gtagttatta tgaaatctat tctcctacac ttgtgaataa 47880
cgagttggca tggaagaaag tagcttggag ttattaatat ggttaaattc ttaagatggt 47940
tacttggttt cagggcaagc gataatatct tacaggtaga gattggtaaa tgtaaagaag 48000
agtggatcaa agtattaaaa gcttttgata ggatgaacaa gaaaccaacc tttacactta 48060
aatatcttat ggcaaagagg acattcaatc tagtacaaag aaaattagat ggttttaaaa 48120
gttgtgacac tatttatgat ataagtggta atcctgttgg atggagactt aataactatt 48180
tctggaaacg ctcagaagtg caaagacaac ttgaagcaag taagaggtgg aggtgaaatg 48240
aagattatct tcttagatat agatggtgtt ctgaacagcg ataatatcct tagcgagtat 48300
attcctgaga ttgatggtga gtattaccct tatcaaaaac atttagtgga taacctaaac 48360
catgctttaa agattacagg tgctaagatt gttgtatcat caacttggag attaggagcg 48420
tctgtggaaa ggttgcagta cttgttaacc cacatgggag tgaaaggtga ggtgataggt 48480
aaaacagata actacacaga cagatttgtt gtacgtggta atgaaatatt taaatggatt 48540
attgataatc aagaaatgtt aggttgtcat cattatgatt ttgaagatta tgttattata 48600
gatgatgatt cagatatgtt atatgatcaa aggaataatt ttgtgcatac aaatggtaga 48660
gaaggtttga cattagaaga tgctgagcaa gttattgata ttctagagag gtaaaatgac 48720
agtacaacaa aaattacaac agttacaaga agaattaaac acacttgaga gagaagtagg 48780
tgatgttcaa gaggtgttag attatttaag agaatgtcaa cgtggtaggg aagaatcttt 48840
tgcttacaca gataaaatgc ctgatgaaca agaatttgag tttaaaggta tgcctgatgg 48900
taaagaagta agtgttagtt tgaaatgtat ttaaatcaat tacagcaggg aatgttatac 48960
gagaataggc ataaacaagt cgagatttat gcgaatggac gatctgttgg gcacacaaca 49020
ggtgtaagtt ataaagtttt taaagagtta acaaactttt gtagtattac cctagcttac 49080
ccaaactatc cattacttaa ggaaggtctg gataactacc tttgtatgtt aagtagtaat 49140
aacataagat acagatgcga ctttacaaat aacattgttg agactgatct gggtatggtt 49200
agattctctt tggtgaacaa caggctcaag gctattcaga ggacgatgtt agttattgaa 49260
agtccagaat tatgtaacca agaggatatt gattaccata tccgcagaga ttacgaaaaa 49320
ctatgttttg tcacacaacc tattaattgt ggttggaggg agtttgaaac acataaaggt 49380
ttagttctac gtgataaaga tactaacaaa cctattgtta aaagtagttc ttgggacaac 49440
ttactgatta attggaaagg tgatgaaact cgtgcagata tagatcaata taaagattgt 49500
gttggtattg taacaggtta tgggtgtgaa caagtgatga gtaagatgaa caaaggtatc 49560
gatttgatgg aagtacaggg tgaatggatc acaaaaggag atattgatct atgaggatga 49620
aaagtagatt attcgatgca gcttgtattt tattaatatt aagctttctt gtaatatgta 49680
ttattggatt gcatcaatag tgtgaggttg taaggaagag tatattgccc agcgaagctg 49740
ggctttgttg taattgagaa taattgttgt ttgtggtata cttacataaa tagaatcgcc 49800
aaggaggtta gattggtaaa agaagaaaag ttaaaaagag aagatgtaga tttctcactc 49860
ctaagtaaag atcctaggtt tgaaaattta acaaatcaag tgtttggtga attgaaaata 49920
cttggacctt atagaaagga atggaagact cttaaatggg tggctgagtg ttcttgtggt 49980
aatatagtta agacttcaag aacaaaagtt aagaaccgtg gtaaaactag ttgtgttgaa 50040
tgtgctgaga tcaagttgag agaaaaacat ttcacaccta tggataagaa gttatcagat 50100
ttaaaaactt ctagagaaga tttaataata cacagatact taggtttaac gtgggcagat 50160
gactgggaag ttacttgtaa aagttgtgaa actacttaca aaagaaaata tagagatctt 50220
attaaaggtg ttaagggttg cggttgtgct aattataata gaaaagattt agatactaaa 50280
caagatgtag tcctaactta ttgtggttat catggttttg aatttttagg ttggaaccta 50340
gataatagga ttaaagtaga tctacattgt ctgaagcatg atcaccatat gacaccatac 50400
tacggtaatg tagaaaaagg tagagtttct tgtaagcact gcaagaagga aaagtataaa 50460
cattataatc ttaaaacaaa agaacagttt atactagaat caaaacaggt acatggtaat 50520
aagtatgatt atagtcttgt agactatatt aattccgata cacatgtcaa gattaaatgt 50580
aatacttgtg ggacagttaa taatcaaacc cctgctggac atctttcagg gaggaactgt 50640
aaatcatgtg cgaaatcagg ctacaaacct aatgagcctt gttggattta cataatgaaa 50700
ttagtcggtc tctgcgaaga atggtacaaa attgggataa ctagttcatt aagtgctagg 50760
ttgtataatg taggtgttgg tagctggtat gatataacct atttagattt caaattattg 50820
gataaagggt ataaagccag aaggatagaa cagcaagtac tcacagagtt agataccaca 50880
ggattaataa acccaaagta ccatagagaa ggtataactg aaatattcaa acctgaagaa 50940
ttaccttttg ttgaggattt attagaagat ttatatatca aggagattta ttcatgagcg 51000
aaccaatctt caaacctgca agtaaaaaac aagccttgat ggttcaaagg gcttctgata 51060
cacaaattgt tgttattggt ggagctaaat aaatccagtg gttccacatt aatcaaccct 51120
gctaattcag gggaacccct aacgtaaagc cgagggcaat cctgagccga atattaattt 51180
atgggtgcaa cgaccaagac tgatgagtgt aagtctgtag gagtcaagtg acttcgaaac 51240
gtagggctat gggtaatccc atagaagata tggtctgtgc tgtatggaaa catacagagg 51300
tttaccggaa acgggtattc cgtaacattt tcaaccgctt acaagctggt agcggtaaga 51360
gccacatact aaaccaccta ccgttattaa tggctgatga cggtaagagt aatgttatat 51420
tttatcgtag aacaaaccct caattagagg gtggtttatg gcctaatggg agatctatat 51480
ggaacagtat cgagaacaat cctgatctac cagatagcat caaaccaaga accatcaggg 51540
atcaaaagaa ggagattata ctcaacaacg gcatgaaaat caaataccag caagcagaga 51600
atgttcagaa atccaaggac gatgcccaag gtcaagaatt cacagccgtg ctcgtagatt 51660
taacatttta ttaacatttg gtttacgagg gtaaaataaa ctgtgtgaat tcaggggaac 51720
tctcacaaga gacaatcctg agccaagctt accgaggaat cggtttgaag gtgcaacgac 51780
tagggtacac gatccagaac ggattatgaa acccgtacat ctaagtagat ggaagcgcac 51840
agcacccttc atgggtgaag atatagtcta atctatatgg cgacatatag ctgcacgtga 51900
tggtgcgggt gaagattaac gaccttcact gaatataaat ggaagctaca caatttgaat 51960
gggaacagct agaatatttc atgtcccgtc ttcgttctcc ttcccgacat ttctcacgta 52020
tgatcatgag ttgcaacccc agccctgacc acaaaatacg tgaactcatt tcatggtact 52080
tgacacctga tggttatgcc gatcctgaaa aggatggagt tgtacgttat ttcataaaag 52140
aagatacaac atacctctgg ggagattcaa gaaaagagct tggagagaaa tacggaatcc 52200
ctgaagagga ttgggaagat aaaatactct cttttagttt tgtttcggga ctaatctatg 52260
acaaccctta tatgcttaaa aacaacaaat cttatgttgc attcctagaa ggtcttaatg 52320
aagtagataa agcacaactt ctcctaggaa attgggatat tcgcagcaag ggtgcaaatt 52380
attttgaaag gggttggtta caagaagtgg actccgtacc aataggtgct gtttgctgta 52440
gagcgtacga ttttgccgca acagagcgta gtcaggttaa taaaagccct gatgccacta 52500
cgtcagtcaa gatgtataga acgaaggata actactacgt acttgctggt gaatatcatg 52560
aatcttttat agatgatgag acctctgtta tggggagggt gtgtaaacgt attggtgaca 52620
gagataatgt ggttattaaa caagctcact acgatggaag tgattgttac atagtgagcc 52680
ctattgaccc cgctgcgagt ggtaaacaag tcttcactga gtttgctaaa aaaatggctg 52740
ctttaggatt cactgtaaaa aaagatcccg tgccaaataa ccgagcaaaa ttacaacgtt 52800
tccttccatt tgctgatgca gcggagaatg gtctcataaa gatagctaag aatacttttg 52860
atccagtaac ttatgaattt attatgaaag aaatggaagc ttttgatggt gagaggagtt 52920
caggcacccg tcatgacgac ttcccagact gtgtggcgag tgcatataac tttctgtgtt 52980
cagcaaaagt ctaccaacca gtatccatcc ctgttttcaa caactcacaa accccttacg 53040
caagaatgaa gaactctctt aattagattc ttgcgtgtct tatctctttt acaactccgt 53100
tgtaatcctc tcacatttca tatctccgat ataacaaagg ttaccgaaat ggtagcctct 53160
tttctttatg tcagctatta ccttcccatt caaacttata cttacaatga cgacatttcc 53220
attttgcagg ataaatcttc aaatcccagt caataagttg gacttgcatt gttccacatt 53280
tctcacaacc tgtaaattct gtgttaagta acttacctag cttatctcgt ctttcagcaa 53340
gtttcttaaa gtataaaagg tcttcttctg taaacatctc actcctccca acttttaaat 53400
ttatacaata actctaattg actactgtac ttccttacac gtttcgtgtc accatcaatg 53460
atactttgtg tcatgttact atatgtgtca gcaaccttaa ctttccaagc taattcgttc 53520
tctgataatt cacgtaaata ctctttgtaa cttagttcat ctttcttcgt cacaagatcg 53580
atagcttcaa ctacttcctt gtcataacct gattgaagta aggcttcttt tgtaacgctt 53640
gtatcttcta agaggtcatg acctaatgct gtggttgata gtttcaaatc attgtctgat 53700
aaattcaaac ctgaattttc tctaaataac tctaacactt tttcttttac catacgaaga 53760
tggtaagtgt aaggtttatc cccatactct tgcccgtgat gcgcaatgat aattaaatca 53820
ctcatcttag attcaaaggc cttaagttta tcgttcatat aattcatcct tctctccttt 53880
catataggtc taaacacaca ataacctcat agctccgcta tgtcaactca tatctttcac 53940
taaattgact tttccttatt aaaatgttat atttgtagga tgttttgcac tacacaataa 54000
ttgcttaaag aggagcatat ttctaatgaa attttatgac caacttacga aaactgctgt 54060
tttcacatct gtgcgtgaat tattgcatgg tattaattgt atgtcaacac gtaaagttga 54120
tgaacattct ggtcacctta cacttcgtgg attacgtatc actgatttag aaggtgttac 54180
agtagcttat accaatccaa ttgaaatctt tgaaggtttg aaagacgact ttggtctccc 54240
tgtagatgtt tctggttgta ttcgtcgagg tcgtgtattc cgtattaaga tgactgaaca 54300
cccttctctt gaagaaaaag agatgcagca gaagcatagt gttgttgtag aagatgtatc 54360
tccaatcgaa ccattgattc aactaagtga agatactcct gaagaattgg ttggagaggt 54420
ttcggaagaa actacactag aaatagcaag tgtgatcgac tgggaatatg tagattctct 54480
taaaaatact aagtatggca aacaagacct tgaaacttac gctcgtgaga aacatgacgt 54540
ggagttagat tgtcgtcgta gccttgcaaa tatgaagaaa gatttgaaag aagctgttga 54600
atctaaataa tatcacacct aatacatgta catgtatacc cttgtaagga ggtaatgtaa 54660
tggcaacttg gaaaagtcgc cgcaagcaaa aacatgaggc taagcaaaaa gttctcttgg 54720
aaaaagctag tagtgaagct cctgcacctc gcttgcgatt aggtgagatt ggtaccacag 54780
gcttagctgc aatccaagat tatattgagc ttattatgcc ttatgagctt gctgactttg 54840
aacgtcgaat gagaacgttt gataaaatgg ctcttaactc tgcggttagt actgctctcg 54900
attttaacta tattcttgtt gagaaagctt ttagtaattt taaagtatta ccaaagaatg 54960
ctcttgatga acaaagtatt gaagctgcta agtttgtaga atataactta cgtaatatga 55020
aaggacaaac attacgtcaa tctgtgcgta atattatcag cttcaagaag tacggtttct 55080
ctttaattga aaagactttt gagaatatac agtatggtaa gtattcaggt aaatatccat 55140
acaaaattaa gaagcttgca ttccgtcctc agcaaagctt agatcgttct attcctttta 55200
aattctctga agatggtcgt gatttagttc atgctagaca gaatacagct ttcttccgtg 55260
agaacgatgg tttcacacca atgccacaac aaggttatta caaagaaatc ccacgtaata 55320
aatttatgtt gtttggatat aattctacag atagtaaccc ttttggtgaa tcacctctta 55380
ttggttgttt ccgtgatgtg aaagagatgg atattatcaa tgaataccaa acagttggtg 55440
tcactcgtga tatgggtggt atgttggtat tcggtatccc tagtgaaata ctgaataagg 55500
ctgcacaaga tccaactggg ttagaggcaa tgagtattca acgcctagaa gagcaaggtg 55560
ctttatgtca cgctggtgag cagacttcta tgatccttcc tcgtgaagta ttggaaggta 55620
ccaacaatat ggatgcctac actatgaaac tccaaggagt ggatggtggg gggaaaatgt 55680
atagtacctc tgacatccta aaggataaac agaaagctat ctttgaccgt tttggtgcag 55740
gtgctatgat ccttggtgaa ggtggtggta gttatgctct tatcgaaggt aagaatacaa 55800
tccactctca ctacatcgaa cgtgatatta atattatcct tgaagtgttt aataatgatt 55860
taattccaca actattagct ttgaatggta tccatcttcc tgatgaactt atgccagaat 55920
tggttgcagg agaaatcgaa ccagttagtt tggatgagat gtctaaagca gctcaacgtc 55980
ttggtagtgt cggtctgtta ccagttagtg ctcctacatt cttaaatgag ttgtatgaga 56040
agcatggatt caaataccgt ctagatgaag agttatcacc tgaagaacta tctaatatga 56100
tgagtgatta tacatctcgt tcaggagaag gtaagggaac gtcaggaaca ggagatactc 56160
aagctgctca aggtggtaac ttaaacatgg aaaataaatc ttttactgat atacgtgttg 56220
atgctaaagg tatctataat atgtcgaaag atggtaagag aacatatatt aacttagagg 56280
atttacccga agaattgcgt gaagggttta atatcaaggg ttaatacaat ataattgact 56340
atttatcgtt gcataacaaa tttagctatg ttataattat taaatagtta cacaattaag 56400
tgataattac ataaaactaa gagattattg tttatgcctt atagagcaaa cgcagtatct 56460
caagcacgta aagatattcc aagtctaaag aatctttctg attctcaagt aaaacgcttc 56520
attaaaatat tcaatagttt agtcaaagat ggtatggcag aaagcaaagc tataccactt 56580
gctatttctc gttctaagaa agacagtgtt gagaaagcta ctaccaaaga tgttactcgt 56640
gacgataacg gtaatcttgt ttatcgagat gagaagtttg taggttataa caaacctatg 56700
agagatagtg gtaaaaagca aggtaaagtg ttggctaaga aaggagatga aatcaaactt 56760
gttaggtttg gtgatccttc tatgagagat aactactctg tagaagctaa tgataggttt 56820
tacgctaggt ttggtaaacg ttctgagata aaagataaat tctcaccctt atactggagt 56880
gctacttatt tatggcctcg tggttccatg aaaggtaaag gagctaaaga attttacact 56940
ctcaataaat cagctaagga aactcacaag atgaaaaatt catttgccga gggattagct 57000
tcattaatca acaaacactt tggtggcggt accaatcttc aacaaattac aaagtttaag 57060
gaagagcaaa tggttgctat cgaacctctc tattgtaaac cactagatgc tgaccttcac 57120
gaagaaggta tgactgaaga agaaattcgt aaaatggttg ataatatcaa caccaacatt 57180
gataagattt caggtaatat tggtcatgct ttaaacacag aaggtttcca tttcgtaaaa 57240
gcttgggtta acgaatgtga atgtgtaatt ggtgaagaag ttgtaccaga aggtcaacca 57300
atcatcaaag ttcaatttac agatgataac ttatgggaat tacgtaaatc tggaaagctt 57360
tgtggtttga gtattggagc tttggggtct gttgtagata accctgatta caaagaagag 57420
gatgataatg aagactccta agaaattgat taaggatgtc acgtttgact tcgataaaga 57480
agaaacaaaa tgtggtcctc atattgcata cactcttccg attcaaggtg gtgctgcttc 57540
tggtctaaat aacagtttcc ttttcaaagc tgaagatgtc ggtgaagaag tttataaagc 57600
cattgaagaa ttaggtttag atgaagtaaa aaaagatttc ggtcttattg aaaacaagaa 57660
acgtcttatc gaagacgctg ttcgtaaaca gtttgcagat gatgatgaat ggttgtggct 57720
catggatatg aatgacacaa cggtttactt ttgtggttgt aaaggtgttt acgctgtagg 57780
ttatacctat gatacagcaa caggtgaagt gatgttagat aagcttgcag aaaaagctat 57840
ccagttaaac atgttcactg ttaaagaagg taagatgaag ctctccgagc aagcagaaga 57900
tgatattgaa gaaggtttgc ttgttattat ggagaaagct cttgaggctg gtgaaaactt 57960
tgaggaaatc gaagttttaa aaacattagt agaagatttc tctcatgtag ataaaccaac 58020
tgcaacggtt gataaatcta ctgaggaaaa agattctgat accgtattag aatcgaacgt 58080
taacgtacca caccctgata cgggtatcaa taaaaataaa gaggataaaa tggatattca 58140
agagctattg aaatctgaag aatttactaa gttcctttct gaccgtgaag cagaaatcca 58200
aaaagctgct gatgagcgta ttaagaaagc tgaagagaaa gctgaagcaa ttgagaaagc 58260
agctaaagaa gaaaaactat ctcgtttaga gaagggcttt actaaagctg tagaaggttt 58320
gtcttttgtt aaagaagaag atcgtgaaga gctagttaaa ggtttggttg aatctcacga 58380
tgtttctgtt gtaatcaaaa tgcttaacat gcttgaagct gcacaagaag agattactaa 58440
gactaaagaa cagtttgcta caactgagca tggtaaagat ggtgaagttg acctagagaa 58500
atcagcaggt gatgttgatg aacttcttaa atctcttgaa gctaaataca gcgacaaaga 58560
atacctataa ttttaaagaa gaggaactta aataatgtct tacactgata tttcaaatgt 58620
ttacctttac ggtaatagtg aacacaaaaa ctaccctgta gatgtagttg atgttgttgt 58680
aactgctgat actaaaattg gtgacatcct aaacgcctct ggtgttctta tcgctgctgc 58740
tgatgaagct aacgcaacat tcatcctaat tgatgaacgt gtaacagtag atggtggttt 58800
ggctgcaggt acacataaac ttaaagtttt agctcgtgac tgtggtgttg gtgagtctta 58860
cattcaagtt gctgctggtg ctgacctagc tgctgctaag actgctcttg aagcccttgg 58920
tttcaaattt gaatcacaac tgtctgctta attaaaggag taactacata tgcttcgtta 58980
tggtgatttt cacgttcaag atcttactgc tgcagtaaat aaaatgccac cagtatggac 59040
tcttgtatca agtctgaatc ttttcgataa agaatttggt gaaacagaat tcgttactgt 59100
tgacgtaatc caagagaaaa ttggtctaat cgacgataaa cgtcgtggtg gtccacgtaa 59160
ctacactaac tctgaagacg ctatcgttaa acgcctagag atccctttct tccccctaga 59220
tggtggtatc cgtccttctg acctacaaaa cctacgtaag tatggtacag ctaacgatac 59280
agttaagttg aacggagtac gtgaacgtgt tatgcgtcgt gttcgtatga accactcagc 59340
tacttctgag aaagcaatgg ttcaagctgt taaaggttta gcttacgctc catctggtac 59400
tactgaacaa tacaattact acacagtgtt cggtcaaact cagaaagaag tattcttcga 59460
cctagctggt tctggtgacc caatcgagaa agctgaggaa gctcgtctac atatcactga 59520
gaacgctcaa gatggtggta gctcttacga agtaactgct ctatgttcta aaggtttctt 59580
tgctaaactt cttaagaacg ctgatttcaa agaagcttac acttacttcg aatcacaacc 59640
aaaccctcta cgtactcgtg taggtggtaa cagtgtttac cgtgagtttg ttcatggcaa 59700
cgttcgttac atcgaatacg catttaaaga tgctgatggc aatgatttca ttgaaacaga 59760
tattgcatac atgatgccag cagggatcga cggcatgttc cgtcaacatt ttgcgccagc 59820
ggatactgta gatgatgcaa acactactgc tcaagaaatt tacatgtggg aaaaacgcga 59880
ccgtcgtaaa gttgaaatcg agtctgagtc ttcattcttg tgtgtaaact atcgtcctga 59940
gctggttgtt aagtgttctg ctgcagcagc ttaatataca gcttgaaata ctaaaaagag 60000
cagccttcgg gctgctttta ttttatcagg agaaaattat gacacaagaa gaagttttaa 60060
ccagtgttta tttagtcctt ggtaaccctt ccacagactt actccctaat gaagttgtta 60120
atcattttat agatcagtgg gaaatattgt ttccattaga tactaaatct tgtatgctaa 60180
cttataaaac tgtaatcagt tctgtgaatt atattataag taagttaact aatgaaggtg 60240
atggtgttga tggaggtact aaacgaagag agaaggaagg tgatgtagag attgaagaag 60300
aatataagaa tggtagtttg gtgggtagtt ggtctgactg gctagatatg ttcctaaaag 60360
atccgacact attattacct tgtcttgctt cggaagaagg cttctcttca aatgcgatgc 60420
ctattgtcac tggattaaat agagagaagt acattaatgt tcttggcaac cctaacaata 60480
ttagcggtgg tgcaaggata ggaagtttat gggatgaaag tgataaccaa aacctagaca 60540
gttttgttag aggcaatcaa tccctttatc gtggtaggcg caggtaattt ataaataaaa 60600
acctccacat aaagtggagg atcttctatt attctaaagt gtgaaaacgg ttagtaactt 60660
aaaggatttc ttatctagtt gtttaagttg tttactgtag aaaggtgcat attggttttg 60720
tgtaaccata gcagctttaa atggacaagg gtctgtatga acatccaact ccctttcttc 60780
tgcaacatct tcttgcacta aagggatagg gtaatattta cctttaaact tgtatagtaa 60840
gaagtcttga ccttgtgcag aatatacacg tactttagct ttaagtgttt tgtgttccat 60900
tataacctcc tttaattaat atactgtaat cataacataa taataaacct attgcaactg 60960
gaggatttat gttgcttaga aacatcccat cggatagttg ggttagtgtc aacagcttgc 61020
ttggtattcc tgtgggaagt aagttagact tggtaaacca aggccaagca gatttaattt 61080
taacaacgtc agatacacaa cctctaggta gttttactgg tggtaagttt cttaaggaag 61140
tggaatctga acaaagtagg acaactctaa gagctacctc aaaagagttg tgggtcagaa 61200
gtaacagctc tacaaccact ggtattttat ttgtacaaga agatagttac cctttcactg 61260
attttggcgg agacttagac ccacgagttt acactggcaa ccaaggtatt acaacccaac 61320
cgttcactga ggctaatgta aagaacggca ctcagttctc tataacagaa gaaataccct 61380
tattaacagg tgaagtagtt taccgtggat ttaaaactgc taatgacgga agagacattc 61440
ttgttaaaac ccgtgttatc aatacagatg gtggtatgag atatacccct cgcacaggtc 61500
aaactggtgt ggtagttggt accaataaag atagttttat cgaaaatctg aatggtaaat 61560
catccaacac aagcggtaca tcttactacg atatcacatc tgtaacaaca gaaggttcat 61620
tcttcgatac tgttaggtct gcaaatggtg taggttctaa cagacagcaa ggtatcttct 61680
ctggactagg tattgaacgt gtacttaatc aagacacaga gtatttactt aaatttgaga 61740
atttagataa taaagaaatt tatgttgtat tctctatcac attttactct ggaccactaa 61800
gtgtagatat aatttaattt atacctttta atataaaacc cactcaaatg agtgggtttc 61860
tctcttttac ttaattttca catatcattc tacaacttca ttaacttcta ctttaaactc 61920
atcatctaca aaagatactg tcacacgttg tggtttctct cctttcacaa tcatatcagc 61980
taactgcaaa gtgatgtatt tcttaataat actcttaagt ggtcgtgctc ccatcttgct 62040
atcaaaacct tcttcgataa gtttagttaa agcttcttct gataggtgaa tttcaactcc 62100
tgagcgttcc tctagttcac caataaattt gttgataatc aacgtagcca cttcatcggt 62160
aatattacta aattcacaaa taccgtccaa tcttgctaga aattctggtg caaatgtcat 62220
ctttaacacc tcttcacgag tttgtgatga tttctcaagt tgtgtttcag ctaagaagcc 62280
taccccttgt ttggttgatt cagattgtct tgcacctaca ttcgatgtga ggatgatgat 62340
atggttatta cacatcatct tacgtccttg gttatctgtg atatgacctt cgtcaaacat 62400
ttgaagtaag aggttgtaaa cacttggatc agctttctcc acctcatctc ccaagataat 62460
accagaagga tttcggctta accattctgt aagtaagcca ccctcttcat aaccaacata 62520
gccacttgat gaaccaatca gtttatttac tgcagtttta tccgaatatt cactcatatc 62580
aagacgaaga ataggtaaac ctagacattc tcccaaactt acaactgttt gtgacttacc 62640
aacacctgtg ctacctgtaa atagtagatt tgcaatcggt ttattatgtt ctttcaaacc 62700
tgacatacca atcttaataa ggtttgtaag ttcatcaatt gcagactcct gaccaaatac 62760
ttgagattta atttcttgat ccaaatcaac aatgtttgtt gaagacttgc caatcttatc 62820
tacatcaatt cgtgttttgt ttgcaataac ttgttctaca atttgaattg ttgcttgctt 62880
tttcttaaga tgttttgttt caactccaac taaatctaag atgtcaattt ctctatcagg 62940
actgtgtgaa gttgttacgt acttctgaac aagattacac aaatattcaa gaaccttatt 63000
agaatattta attccgtgtg cttgttcgta aagatgtttc acacctttaa caataactct 63060
tgtggcttct ggtgatggct ctaatacttc aaccttctgg aatctacgga agatagcagg 63120
atctttttct aggatcttat actctttata agttgttgca ccaataacct taactttagg 63180
atttgtgaga tgtggtttta acatattacc gacatcaggt gttgtctctg aactcttgtt 63240
cttaatctga tggatctcat caataaagat aatacagtta ccatgtttag ccacttctgt 63300
gaaaatctta gatacacgtt cttcttgatc tcctcggtaa cgactaccac ctgttagttc 63360
agtcatatca atttcataca aatccatatc tctcatataa tcagggattg atttatcatg 63420
atctacgagc ttacaagcta gatcttcaac aatactactc ttacctacac cactttcacc 63480
tacaaggatc ggattagctt tcttgtaacg actaagtgtt ttaatcatca aatcaacttc 63540
actttcacga ccaatgactt taccatagtc accttgttta gcgcaaagtt tcatatcttt 63600
caagaattta ctaacttctt tactgaattt aaacttagat ttggttttaa cagcttccat 63660
acttacctcc ttgttaggta atttcttttg ttctgttata catagtgccc ctagggcatt 63720
acttaaatca tccatcgaat aagctgaata atacttatca aactcttcca tttctcctgc 63780
agattcaatc tgacttaaga tgttgaagat gttttcttgc ataacatcaa tactaacttt 63840
ttgatatccg tatgcagcga atagatatct ctcttctaaa ttaagaccgt agaaatagtt 63900
ttgtcccatt gtgttataca aaacccaatg ctcacaatca tgaacgtact tattgtatac 63960
atctatttgt acaccaccta ttgcacgtaa cttagtaaca agttcgttat accttgcttg 64020
agaaatacct tttgatgtga aaaagaaacc ttgtgtcatt tgtcaaccct cgctcttact 64080
tgtgtctgta cttttaatat acaacaaggt tagaagatgt caacataaaa tttacaaatt 64140
ttagatgaaa gaaaacccac cgaaaggtgg gtttggtatt gacaaaatta atcactcgtt 64200
aacttctgac attgtaatta tggagttttg caaagttaat gtctaagtgt ggttttgtgt 64260
aggagttacg ccgttttcgc gcagtaactc ctaaggcatg attatgtaca gcaaaggtga 64320
ttggcatgat gtggtttggg ctgttttgtt tgcgtgtttt atggcgtgga ttttcattca 64380
ataggaggaa gtatgtttta tttgtggctg gcaatactgg cgctatttgt aagagtttgc 64440
tatgttagct cgacgattcc aagaagtgaa tatgataaag ccccgtagtg gggctttgca 64500
aaaaattaat tttgatgatt ttagcaagat ggaaaactaa ggtgctgggt cttcattagt 64560
aatctgtttc cagtctccgc ctgatgaggt agctttaaac cataccttgc tggttgtatt 64620
caaccactcc tgaccaaaga actcaggaat gtctgaaaca gttggatcgg tagatgatgt 64680
tataaaatca tccgttggat cgtatggagc tattgtttca ccatcaccaa cactggttgg 64740
tattgatgag ctagatcgca tattaccaga tggtgttatc cataaatatc ggtttaacca 64800
tctgacaggc tgcttccacg aaccaaaacc ctcattcgaa gctatgatat tggaggttaa 64860
ctcgtaaacc gtcccgccac ccaaaactgt tgttacattg ttatcgaata ttctagttac 64920
ccaccctgta tttgtgccgt taaacttgaa tgttaggtcg ctaggtattg gcatgctcca 64980
attattgccc tcaaaaataa aactgaaacc tacagggcat gaatcacatt ggaataaagt 65040
ggtggttgtt tgtgtgattc ctgaaaatag gtttgtcttg ccagttgtaa atgactcaag 65100
accaacagcg ttcatgaagc gaccgttaat gcgttcgaaa tggttgcctg ataaatctaa 65160
gcctcgcgtg ttgtttaatt tgaatacttg tggtggagct tcattattgc ttactatcga 65220
ggtgcatcga acaatattgc cctcaaatct cacggtatca ttaccgcctg acgtataaag 65280
tacgtaaccg tcagttgtcc atgttgagtt tccgtaacca agtctaggac aatccttaat 65340
gaccagaccg tctgggtttt tgactcgaat ttgtttatca acacgctgaa gaacacactc 65400
tgaaaatata ttgccttcac agtaatcgag ctcaaatcct tgaggactta acgttggtgt 65460
gtctgtcaag ttaccaagcc taacccactc attgtggtta tagccaccga gcctttcaaa 65520
tttagataat tttacacctc gaccttgaac aaatgatgat gaaccgccaa gaacacctcg 65580
gcagttaaag tcatgaaaat acaccctgct caaatagttt aatgggtctt gaactaaagc 65640
gtcaccctct gggtattgtc catcagcctg ctggcaaatt ctaaacattg gaacgtcttg 65700
atcaatcagc acgccgttat tatcattagc ggcgccacca cctccatctc caaacacctc 65760
ccatataccg taacagactt ttgtgtcttt tttgataact tctatcgtgt ttgataggcg 65820
aaaaagatta tttgcggtcg gaatgtatcc gggaacgggt ttccttgggt tgctaataca 65880
aaaatctgcc caagcttgaa actgtgcact tgattcttga gcggctgtcc tatcaggcca 65940
gaacgccatc acactcaacc ctctaactgg taacaggtag ttgcttatgt caagaagcca 66000
aacttcatca gttccaacag tcgcactgta tggtctgatt gttaggttga gattcgaaac 66060
aacccctgaa acgcctccac cagtcccatc cttttttaat actggaaaaa tcgtaccttt 66120
agagaaatcc ccaccaacag ctcgaaggtg tgtagttcct gctggaacag tatcaccatc 66180
acttaatgta ccaatctctg gataaatttt agaacctgca ggtaacaact cctcttgcgc 66240
tgtagtatcc cacccttgca caatgctact attcttacct gttggtgcta gtcgccaatt 66300
attatcacca acaggagtag cacccatagc aatagggttt gtcaacgttg ccgttggtgc 66360
ccaatatgtt tcatcaccaa aagtacgtag ttggttaaaa gctgtttcat tatttcctga 66420
atcccatgca actggttcaa caaataaaaa tgtatctgca agtgatttcc ttacacttgg 66480
cacaggacca ctttctgtca tcacttcagt agtggcattt tcattaacaa tctcatgcat 66540
ctgatttgat acatcaatca atagttcaga tgcttctttg ctatttgtag caggatatgt 66600
catatacatc tctcttatta taacgtgcag tagctagttg cacaaaatca tgatttctga 66660
ggaggatgtt attttatacg ttaaacaacc tctcatataa ggtatgtctt acaatttatt 66720
gtatattatt gattgacata ccctacatta taacattttt agtgagattt gtattaacaa 66780
cagaatttat ttggtgtaac agatgtaatt atttaacaag taatctctgt atgaagttgt 66840
aagaggtttt agaagaaaag atgatacatt gtattacagg tataagaaaa acctctcaga 66900
gagcttccaa gaggatttaa acaaggttta atggtgttgt tttatatact aggaatactt 66960
accaaatatt tttcttgcaa aagcatatcc acttaccgca agatacataa cacttgattt 67020
ccatttactc acacctgtca aaagtaaata ttggtggaaa actttatctg tatattgtct 67080
aagtttgtaa tcattctgtt cataagctaa agaacacatg aaatcgtgca ggagagctgc 67140
gtcaacacgt tcatttttga taagccaagc aaacatacta ggaatactat atccgtctgt 67200
cacgtagcct acagggacga tatacacact ttcttctgat ctatcaataa tgttgaaagt 67260
tgtattctct tttacaacat ccgttttgtg atctttgtcg ttatgatgta gacataagta 67320
agataaatct ttgttgcatg taagtatcat tgtctcacct tccttaatat ctcttcttcc 67380
aaggttcgaa accccccaca ttttaggttt accaaacgtt cctgtaaaac caaggtcggt 67440
cagtaaatct ttctctggag caatggaatt aaaaacgtca taaggttcaa ttttcatatt 67500
attattatca ggtttatact ctattccatg tttaactaac cactttgaca cttcttcagt 67560
taaaccgtaa acattaaggt aggaactaaa ccaatcactt atggtattac gtaatttatt 67620
ggtaagtttt aatcctagct tgttcatcca tttaaaacat ccttcccaag ccatctgttc 67680
tttgtagacc acaccacctt cttggtcttc tgtatggtga ccaagttcat gtaacaatgc 67740
taaaattttt aaatcctcat catcaaaatc ccacagaatt attttatgca tttcctctcc 67800
gtcagatgta ccagaaatat aactggcgct attccttctt gcttgccaat ctacagtgac 67860
tttattaccg atatcacttc cttgtacgga tgtatgtaca gatacatcta gaaagttagt 67920
agtaacccac ttttcaactt ctgaatattt cataataacc tccaaaataa aaactccctc 67980
atcaagtaaa ttaatcctac aaggtgagag attttgtgtc aagcattgtt tagggtaatt 68040
ttactttaga tttacacctc tggaggttaa ctttattcaa taccatccta tattgtacat 68100
tatcattgtg gtaatcttta aaagaatgtt gtaaagattt atcttcaaac tcccatgtga 68160
aaccataacc atcaggagga atcaatttta tatcatctat cttcagatta ttaataacca 68220
tccaatcaaa aattatctct tcgaattgtt taggataatg atccagatgt gcctctgaag 68280
gtcttatctt taaacccgtc tcttggcatg ttagatagcc tttgtcaatg ttagacctta 68340
tgtagtctct tctataatta ttatggtaag gttctattac tttacgtaaa gtttgtttta 68400
atttagtttc tttggaataa ccatttatag ctttataata actaaaatcc tcaatacctc 68460
cacattcaaa atgaatttga aattgattat tagcaggatt cataggacaa ttatcaacta 68520
ctattgtgta ttttctacct ttaacctttt ccttgtatct aggatgcatc ttaaggacat 68580
ctttcataat ttttaaatct tcaccttcaa gttcacccat gtttgtattt aaaatacctt 68640
tacaaaactc aatcatagct ttctttgtat aaaaaggttt accacctata atatacttta 68700
ctttcttcat attaatcttc tcctatatta caatttaaat cagaacccat tactaaccta 68760
tacccttctt ccataaaact tttaactaaa tcagcttcag attttttaca aactgtttcg 68820
tcgtgtagag gaagaatcac gatatcatgg tttatacatt ttctgataat aaactccatt 68880
atcttactat cataattcat taattttaaa cctatacctg tgtaaaaata cttacgtatt 68940
ggttcgttac actcctcaat gatatccatt atttgtccga tatcaggatt aataggtaaa 69000
ccacaaaact tgatagacga ttctctttta gggcaaccta ttttggatct ctccaaatat 69060
aacttattaa caacggcaga tatagcatct tccctactac aggcgttaat catacataac 69120
ataactaact tacataagtt tctctctggg ttatatttat cataaccgta atacttttta 69180
aacttgttaa ccaacacctt actgtgtttt atcttgatga ttgggtaagc gtcatgagtt 69240
aatttgatac cttctaactc atataacaac gacggatgta atgaatcaaa atcccatctg 69300
acagtagact ctttatcaat tgtcgtcgtt ttccttgata gtttatcaaa cctttggtac 69360
tgaccgaaat caaagaatct gccacataga tctaggttat aggtgtaaat ccttttaaac 69420
catatatctg gtattatatg accgttaaca catataaccc tcgaatcaag tgcgttgtta 69480
aatgtaatca ttaattcctg atcttcttct atttgatgtt cccattcagg tattatctct 69540
aagggtagtg attccttcct tttcccgacc tttactttct ccctaacctg aactagctca 69600
tcaagtacta ggttggtatc gattaccttc tctacaccac tgtaatactt cgataaatca 69660
ccgacaatta tcatcaagct tggaacagga tctccttcag aatcagaatc taagttataa 69720
ccagagagtg ttatgatttt cttattatat tctaggaaat caaccagatt atgcattacg 69780
gtataaggaa aacttaaccc tagttccttc tttgttttta tgtaagatat tggtgctctg 69840
taataagata tcgattgttt accttttgat aaacacctag ataggttata aataaaccat 69900
tcacatacca cctttatctt actggtatgt aatctcctta acttcttcac ctttttaaga 69960
tattctagaa attcttgata caggtaatca acatacaact caaactcatc atctggggtg 70020
aaataagtat gtgccttaac agatagatga tctagagtat aactaagaga aagacttgaa 70080
tggtaccatc tactaagatt taaatcatct aaacaattta ataaattata taaaggtaaa 70140
gaggacatat agtgtgaaag tttaagggat tttaaaatct catcatcaat cttacgtaac 70200
cttttgtttt ccttggatat ttcagtaggt ttgaactcga atgaatactt ccaatcacac 70260
tttttatcac ccgaaattgt taagtttttt ctctttttct tcttgtaaac catagcactt 70320
tgcctcttct aaactcattt ttggattctc cagtaagaac ataatgacat cttctggtgg 70380
tgtggaagta gctctcaccg tagacataag attatccata ccttcagaac taatttttcc 70440
tatattcatt tcttttcctc tacagtaaaa ttaatagtta acccaagact acataaacca 70500
ttcatgactt tctctaagct aacctcttta cctttatgat tgataatatg gttaacctgt 70560
gttttactca taccacatac ctttgccacc tcagaaaaag aaaggtctaa aattttaact 70620
ctttctgaga aaagattgca caagttctct ttcataaatt aactcctata tagatattgt 70680
aacagattcc tttacctatt acaactttaa ataaatcact ctttcacaca atacacagcc 70740
ataatacgat ctggggcatc ttctacaact ttagcttctc ttccccaacc aacagacttt 70800
tcaacaatct ctaccttagc attattacac gcttcaatag aatcaaaacc gcctacgtta 70860
acttccatag tgtgtcccgc agttgatttc atcattaaca gaattactaa tttaaacata 70920
agttcctcct ttatctacca ttcatactta atcgtaaaga acacagcact acccaacaaa 70980
cccacaactg gttgaacttg acactccgta tacgcaacgt aaggcaccac aataggcatg 71040
aaacgattat agttaaggaa gtctacatct tcttctttat agccgtaact gagccctaca 71100
aggcttccat attcgaaatg gttgtattta ccaagaacaa aattataact cacctcaaca 71160
gtgtaatcat tatgtgaatt gataaatcca ccaatctgcc aattattata ttcgtaagca 71220
tggaaccaat gtgtttcgtt atcagcttct gtattcaagt ggtgactcca tccacccaag 71280
tatattgctt gatctgctgc cagtgttggt gcagataata atgataatgt tagtagtaat 71340
ttattcattt ccaaaactcc caaaatttct ttttagtgac acgtttactt acaaaccaac 71400
catctttact acaatcacta cacacatcaa aataaccaga actcgacaca aatgttgcat 71460
gttttgtttt acaaacagga caaggataat tatgagttgc aaccatacca ctatcgtgca 71520
tgaacatttc aatttgaggt aaagttttac aacgttcttc agcatcatca taagaaatga 71580
aattttttcc attagtgtaa taagctgtgt agttatcttt ctgataccag atactgcttt 71640
ctagtttatt tatcatttat cttccttaac aaatcaacca taagtttagc gctctctcga 71700
tcatattggt gcccaacacc accaactaaa tggattagta acagtttatc taagttatct 71760
gaaacctttt tagctagttg tctttcttcc tgtgtaaatt tattcatcac aaatctcctt 71820
acctttatac cacaaattta caattgacat tggttgtttc aaaacctctt cctcagaaaa 71880
gtcattatac acactgacaa taagactttc tagttcacac aaatcctcga tagagtaatt 71940
tacttgctct tgaacaatat caatatcttt gctgatacta tcctcgatat ctttcatcat 72000
ttttaaatct tttattacaa cttccttggg accccaatgt ttttgcatac cactagggat 72060
taaaccatca ggtaattgaa aagttaaatg gtgaccatta ttctttggtg atgtaaagtt 72120
accaacctta gtttttacac catctaggaa aaccttcatt acacctttac gtctacgaac 72180
agtgttgtta ttcatcataa acctccttga taaaatcttc acaatattta gcaaaatttt 72240
caatatcttc ctctgtcatg caacattcca tatagctaat ccaagctgat ctcatcttat 72300
caataagttc catatccttg ttatcgtgat ggagttcgta aaagctgata gctttcatag 72360
cgttttggtg gaactcttta gtaactaaca tctttttact cattgaaaaa actccaccat 72420
ttcatttaca gcattagaaa attcacactt attagatgtt ttattgtaag actctacact 72480
atctataaac gtatgacaga atactttatc tgtgtacgat tcagagaact tactgtgttc 72540
taatgtaata cttttaaagt tgaaagcttt tgaggtttct gaagaccaag taggatcttc 72600
ggtgacacac aagtattcaa tctcatctga acagaaaatt tcacgtttta agtacaaagg 72660
gaactcatac tcccttttga tagttttact tttaacaaca acttcttcat tgataatctt 72720
ttcaaaactg tatttcatac cactcatcgt tcaatctccc atccgttttg tttacaaaac 72780
ctttctccag cctgtaaagc accattgtaa ctcttacatg ttttctgact gatcaagtta 72840
gttctgttgc ttttaatcat aaactggtat gttcggtatt cgttaaaata tcgtccatga 72900
cttgtgtaat cagtaaataa cttaactttc ataccctaac ctccttattt tccacaccac 72960
caacatttct tcttaggttt aggtttgatg gtacgatctg tatctgtttt gatagtaggt 73020
tcattcttaa gaacaatatc tacaacatcc gcgattgtat tacacttctc ccaatcttca 73080
tcacaaatat ctgtatcaaa ctcttcttct atccaaagaa gtagttccac atcatccaaa 73140
ctatccatga gtaaattata tcttgtggta tcttttgaca acactgttgt gtcatcaatg 73200
ttcttcttaa taatattaca aactttatcg tatacagcta gttccagttc ttcatttgat 73260
aacatattat tctcctttca tctcaacttc ataaccaaca aaactatcca attcttcttt 73320
agtcaagttt tgtaatgcaa acacactgta acctttgttc atgtaatgtt caagaagata 73380
cttattacgc ttgtgtgccc agatagcagg gaataaccaa gctgtaaggt ttgtaatatc 73440
tgcactacct gccataacta acaacatgtt tgcaacaatc atgaataaga agaatagaaa 73500
cgcattcttg aaattaccac gaattagatc agggaagaag ctgaagagta gtgtggtgaa 73560
tgagtatcca attttaacat ttgttacttt gccgtatttg ttctttagtg ttacaatttt 73620
catattattt ctcctcatac aagaaaccaa tctcgataaa agttactaaa tcttttctgt 73680
cgttatcatt agttatatca aaaaccctat ccacactgtt agcccatcta tcgaaaacag 73740
ggacaggaca actaagttgt atcagcttat catctagtat tcttaacttc ctattcctac 73800
actcagagtg aaggccatca ttactcagtg gcagaccaca gtttataagt aaatcatctg 73860
gtggtagata ccattctctg cagaaatcat aataattatt aaccataact ttctcctctt 73920
gtttaagtta catacatctt aagataccag atcaaccatg tcaacaaatt tcttcaaatt 73980
attttcatat aggtaaaata aaacccacct aagatttctc ttaagtgggt tgagtaatta 74040
tttataatct tcagatacat cttcaagatc tgtatctttc attaagtaat ctaacgcagg 74100
taaagagtcc atgtcaaaca actctattga ccattgccca tttggttcat tgtattcgaa 74160
accacgttca cgaagctcag agtggagcca ctgctcagtg tcgtacacag tttggtggtt 74220
tgatgtgtat actgatagaa tttcaatctc actacgttta tgatctgata gtttgagtaa 74280
cgcctttaca cgttccgtta cgttaaagct gcgacctatc ttaatatact tatcattaaa 74340
gtttataacg taaagatagt cttgctctcg ggctcgttta ggataatatc cgtagaatga 74400
accatcctca cgttgtttta ttaaacggca agtcatacaa cgctggttat gattcaaaaa 74460
tccattcaca ccagtttcac atgaatgccc ttcactgcac aaccatttga attttgaaaa 74520
ggtattcttg tattcatcac tccaaccaac aaacacacca ccttctatag caaacacatc 74580
attgatttgt tgttcacgtt cttgttccgt ccaacgttta ttgcctgctt ccaatgggca 74640
accttgcccg ttattaagga aactattaat atttgtagat tgccatatat taccgttact 74700
tggattatgc aatttaaggt atgtatgagc accagcccaa tcgccaataa aacctataaa 74760
ttgataacca cgctctgcac atttacgtct aactaaggtt tcgtattgaa gcgcactcca 74820
ctgaggactt ttagagcatc cacaagggac cctttcattc acaaggtcac tttttacact 74880
ggtaatactg ccgtaaggcc atagttcagt atcctttgaa caaacttcac attctaagat 74940
aaatttacgg tgcccctctt ttatagaatc caccgctttg atatacggca tcttttcagc 75000
aagcaaccta tttgtgtgaa ttaagtcttg tcctggtgtc aactgtggct tttttgcaca 75060
ataacacgga atattaccct tttcaaggtt accttttgtg ctggtaaaca tatcaggaaa 75120
caattctttg tcttcactac aaacactaca ctctaaaccg aatactgcaa tattaccttg 75180
tttgtgacta acacacgtaa cagttagtac accaccttta tcagttggaa acgttgttcc 75240
tacaaaccta cgttgtcctt tcgtccattc actttctgga atacctgttg tttcttcgtc 75300
gctgttactc atatactttc tccctaaata ttatatcatc ataaacatat cttcatatat 75360
tgtcaacagt tattttcgca tctgattatg ttataatgag agtaagaata attatcaaca 75420
acaaaaggag atcgtcgatg tcgagcataa atatagacct cgttgaagcg attttaaccg 75480
agaaacatac atctatccct aagacaatga ttcaacgact gattaaagag tctacagcta 75540
aaagttttga tgacttgttg agagatgtag agtcaaaaat aacatatgaa gaacagaaag 75600
aagtgactcc acctttgaga agtaaaggta gaaaacatct attagatttt agtaggaatt 75660
ggtaatggaa attgatgtaa aaatggatga tagtttggtt agagaacttg agaaagagct 75720
tgagtggatg tcaacacaaa ctgttgaagt aggatacttt caagatcaaa cacaccaaga 75780
gtcaggttta cctctaccaa ccttagctat gtacatgaat aatggtgtca aggctaaaga 75840
aggtgggtgg agaatagtac cacgtccatt tatggatatg agcttttact tcattggtga 75900
tgaaatacct aaatataacg ctattatgca agacagttta atgtttgggg gtagaaaaca 75960
aatcgaatta ggtttaaaaa tggtaggtga tatggcagtg gatacaatac ctgaagctat 76020
agagactcaa gacttcgcac cattaaaacc tgcaactatc cgagctaaaa attccgatgt 76080
aatcttagtg gagacttcag aattgatgaa ctcaccgcaa gcgagaataa caacagaagg 76140
aggtaagtag tggcaatcag aaattccacc ctgatcaagc ggtacaaagt gccaatggtg 76200
tatcgtaggt acgatgatag tgccaatacc agaccattcg ataacgaagg tggtgaaatt 76260
gtttttgata aacgtgttgc agaagaatgt acaatacaat ctccgagtag gaacaacaca 76320
acaccagaaa tgcaaggtct agatcctaca acaacttatg taatatatac aaacagttac 76380
gttcctcagc ccagtgacgg agagaatgac caaccttgtg gattttatat ttcatctgct 76440
tggttgacgg tagatccttc ttaccctgca aatagtggtg gttggtataa agttgtgagt 76500
gttcaacaaa aattaaaccg tgttatcaat cattataaag ttgtagttgt acgtgatgat 76560
aatattacaa atggtgaata tccagataca acagtttttg atgcagaagt tacaacacgt 76620
gatgagttcc tgtctggaac gtgggaggca acatggctac taccttagaa atacctctct 76680
ttaaagatag tattgaaggt ttaaggataa atgttggtac tatgctagac caaacttttc 76740
cagaccacaa gatactattt gcaaactcaa atattattgc accaaacgag aaagctattg 76800
tactaaaacg taacgttcga agtggtaatc ctaatggatt aaacttagtc cctatcagtg 76860
tacacattga tgccttgaca ggagagaaac attacgtata tcaagctaca gcaagctatc 76920
gtgtaaagtt tcacaaagaa gcatccattg atgaagcgta ttatctgaag atgttacttt 76980
ctactgacga gtttcattac acatggtggg gaggtaatga cttatatgga attacaaaca 77040
ttagtgatgt agctgacgat cctgtgagtg tggactttaa agaatgggaa gaaggtgcaa 77100
taataacttt cgattgtact tatttattcc gacacacaga aagcgatgct aaaactattg 77160
aacgtatctt gtttacaagt aataacggaa gtggagtctt gtcaggtgaa tcggagaact 77220
tctggatcac attaggttac tcaagttacc aagattatgt ggataatgtg aacacacttt 77280
attttcatgt aaatggtgat gataatacac caagtggtgt tgacttctca caagattggt 77340
aaaagttcca tataacaata gactatggca taaaaataac aaatctgtta taataaacct 77400
tacgcagaaa catatcaaga tatttattat tatattttga tacccacctt tctctacaga 77460
gaactatctg tgtaatttcg aaattatata agttcttccc tattatagag gattcaagca 77520
tggtttttga cggtattaac tccgttgagg tcacattagg actaggtact cgctttggtg 77580
aaacacagag ctttaatatt ccactagtag tgatcccaca caatttatct gatgcacgtc 77640
tagcagcgtt tgcatcaaca caatctctgg cagacttagg tgctgcaaca aactctccag 77700
tttatcgtta cgtgacaggc tttttcaacg gtaacttccc ttctagtgta attaaagtcg 77760
cacgagcagt tctagatgat atcgacgtaa cagttggtga caacatccca gaacttggtg 77820
aagatatctc tgtgaacgta gttgtagacg gtgtagcaaa agttgttagt catacaatga 77880
caggtacaga gacagatgct tctactacag caacagctct tgcatcagca atgactacag 77940
cattccctgt aggtggcggt aacccaacat ttacagcagc aggtccagtt atcaccgttg 78000
taccagatac actttcagta agtgtaggtt ggaatagttt agatgacgaa ggtgtgcctc 78060
atacttctgt cattgacaac acttcagaag acgtagtaac tgttattaat acagctacac 78120
aagttgataa tgattaccat ttcttgatgg gtgaatcacg tttatcagcg gatgttgtta 78180
agtttgcaga ttttgctaca gctaatgata agcaatatta cacatcaaca ggtgatgcag 78240
aagtagctga taatgctgat acagataaca ttgcaatcac actaggtgat aaagctcaag 78300
acaatgtagc attgatgttc cacactaaag atacgttcta cttcccagaa gcaacagttg 78360
ttggtggtga agcaggttta caaccttata atctacagaa ccctaacttt aaaacgttgg 78420
aaggtatccc agtagattac atcactgaag cacagttcat cacactaaca caacgtaatg 78480
ttaacttcta cgttaaagaa aatggttatt ctgtttacaa agaaggttgg acacaaggtg 78540
gtaacttcac tgatacaatc cgtaacagta tttgggctaa ggttcgtatt gaagaaacat 78600
tgacagcact acttaaagag tatgccgacc gtggttcagc actaccatac agtgatgtgg 78660
gtgcagctat catggaaagc cgtgttctta ctcaagtaat caacgttggt attcgtggtg 78720
gtacagttgc tacaggtttc acaacagatc ctgatacaaa cactactatt gacctcaacc 78780
ctgttgttga tttcggtaca cgagcacagc aaactaacgc agacattgca gcacgtacat 78840
ggcgtaatgg ttttgttgag tatgtataca tttctggtgt taacaaaatc aaagttaacc 78900
ttaatgttat cctcaaccgc gacccagttt aataggtgaa ttaaatgcaa gatacacaaa 78960
tttataaata cgatccgaaa gaggtgatct gtcttgtagg tggattccct gttcgattgg 79020
caggaccact tgttgtttct cgaacaaacg atgctacaac agaacaggtt ggtcaaacag 79080
gtcaagatat ctgtgtcaac gtcaaccgta acattatcgg tactgtcact atccctgtta 79140
tggctcaatc agattatgac acaattttaa cagagctagc acgagagcca cgagtaacaa 79200
gcttctacct tctagagaaa tctactaaga agctcatggc aacagaatgc tggtacaaga 79260
cacaacctga cttgtcactt ggtgaagaag tagagttacg tggacacgtt gtaactgtag 79320
ctgatgcaac catgtccttg acaagcggta cagaaagcct aatcaatcag atccttgagt 79380
tagatttagg ttaataaaga gcaacatgtt ccacaaggat gtggatcttt cttgcaatgg 79440
agtgttaaca gaattaaaga ttgcagagga ttgcagacat gacaaataca aataaagatt 79500
tccgtaaacc agaaatcaag aaagatgatc accttgcaca agcgattgaa cgtcaacaac 79560
aatcaaagcc cgtaccagaa gagagtaaaa gagaaaaggt agtaacagtt aataagagaa 79620
aataccttat taagagatgg tctaatacag aggctatgag aaaacttcct actgtagcaa 79680
atcttctttt tgttcctgta gcagctcctg tagccgaagc taccgatttt agttcaggtg 79740
gggatgtaga gattatacca gaactgttta gtgcagcaga tgtaatggtt gttcttttcc 79800
aaagattcca agaggtggac ctacaagcat tctttagaga tatcttggat gagacgtata 79860
ttcacgggga agattctcct gtagatttcg atgaagattt tgataaggtt acagatatta 79920
tcccagtagt cgtggaggtg ctacaagcaa attttatgat gcagttatgc agggatttgt 79980
tcgggatgac gacagagaat ctgtgggttc aagaaataaa tctggcaatg caagcttcac 80040
accaaacttc gaacgagcag taaagaatat agagaagaca caatccaaac aacattacgt 80100
tgattatata aaagcacgta ttttgtatga agaaggatta catgaaactc tatacacatt 80160
gaatgaatac acattgtgtg aaatattctg gttgtatgag cgcattgttg tgagagatat 80220
gatttttgag gctaaagata gagatgatca gcttaaagag caaatgacag cacatcacag 80280
gtagtgtatt agcatacgca atatttaatt gagcgaggta atgagagtta ttctcgcctt 80340
gcttttgttt tagtaaaaca taggaagatt cttatggcaa gaacactcta caaatttgta 80400
aatgaagtga gatggcgtaa tcacttacca tcgtggagga aggttaaaaa agaagcacag 80460
cagttaggga aagaaatagg tgatttatat aaacctacaa taccttcgcc tgacatgcca 80520
agggtaccaa ggcaacctca tagacgttta gatgataatg atgcacatat taagcaatat 80580
agaaaactta atatggagca agagaagttc gctaaattac aacagacggt aataaaacga 80640
ttctctattt cgaataaaga aattcgtgag atgggagagc ttgaacgaag aagttttatt 80700
actcaactaa aacaagcgaa aacaaaagat gagttacttt ttacagaaag gaagcttaaa 80760
gcggaaatag ctgataggct gaggaatgaa aaacgtctga cacaagagaa gaataagcag 80820
acgttggctc aacgacgatt gacatctagt actgagcaga tggcaggtag tttagtttct 80880
gtatatgctt tagccgcatc aggtcaagct ataacaaggg tggggatgga cttcgagtcc 80940
tttgaaaaaa ccttcctcgc cgtatctgac ggggttgaag atgcaaaaga ccaaatggag 81000
tttgcaagac agacagctca atatttcgga tcagatttga ttgagacagg taaggcttac 81060
tctcgtatga taggtgctgt aggtgataaa gctcccctgc aagacgtaag agatattttc 81120
ttagcaacca atgaggcagc agtagttcta ggtctatcgg cagatgatac cactggttct 81180
ttacgtgcaa tccaacaaat cctcggtaaa ggtcgcttta tggcagagga agttcgtcaa 81240
caactaggta aaacagaata ttaaactatt gcctagtata aatctctcta atgctggaaa 81300
ctctctttta attgtgttat tgttattaga gacaatcagc agcgaaggag attcactatg 81360
agaagtgtac cgataaaaca taacccgaac tatattcttt atgaagatgg aagggtttat 81420
tctaaatata aatcaatctt tatgtctaca tggttggata catgtaaata tattgttgta 81480
ggtcttagta tagacggtaa gaaatcaaaa ttcttaatcc atagattact agcagaacac 81540
tttgtccata acccagatcc agatactctt gtacaggtta atcatatcga cggtgataaa 81600
cttaacaata aaatagaaaa tttggaatgg gttactgcag gtgataatca acggcatgct 81660
tacgagactg ggttgaaaac tatacctata ggagaagcca atggaaggtc tatactttca 81720
gatcaagagg ttattgagat atacaataga ctcttggcag gagaatctaa cattagtgta 81780
gctaaggcat acggtgttga aagaaccaca atatttggga taaaatgtaa aaagaattgg 81840
cagcatttaa caaaagattt acctgatatt ttcataaaag agaagccaga caaacttaca 81900
gatgaaaagg ttcatgaggt ttgtaaactt ttagttgaaa aagttaaaca tcaggaaata 81960
tcagatcgtt taaatgtaag caaacatcaa gttgcagata taagcaggaa aagatgtttc 82020
aaacatatat ctgatcaata ctcatggtga gctctgtgct caacgaccag ccgtgatgag 82080
tttagcggcg tagggtgtaa gctaatgaca ccccaaacgg gagactgcct ttaggtagaa 82140
gatatggtct caacttctat ggtgacatag agaagctcct taacatcggg atggtgtaaa 82200
gaaagctggt aagggtgttg cgacccttat tgaagataat ggatagaatg cccatattcc 82260
tacgtgcact tgaagaaggt gctaggaatg cggggcttgc agttgacgaa gtaggcttag 82320
ataaattgat ggagcgggga gaattatcgt tatcgatcct gccttttgtt tcaaaggctt 82380
tatctgatat agcacgtaat aacaatgcag ttgagaaagc tatatcacaa aactttgctc 82440
ctgcactagg tagggctaca aacaccttaa aagacctagc taatagtatt tttaaaggta 82500
tgaaaccagc tatggttgcg gtgttgaact cattcagtgc agtaggtgat gaaggtaaga 82560
ccttagcaaa aacaataggt tcatttgttg gtggggctat cacaggatta accttcccaa 82620
tagctatgtt agttgcagga ttgactgatt tagttacact gttcaaagaa ttgacgggta 82680
tatctgatga aacatctgaa agcttcctta catttggagc taaagcagca ggtattgcag 82740
caggtttatt tggcctttat aagatagtta aattattggt gggtggtata aaaacactaa 82800
ctaaaggttg gggaatgttc acatcagcag caggaaaagc aggaaaagct gttgacggag 82860
taacttctgc agcagggaga gctttaagta tctttagcaa actgttcggt gtgatttcat 82920
ccttaatggt tgtatgggat gctagagcgg gtggtgactt atcagcaaca tccttgtttg 82980
gtcaaaattc aatcacggag tggctcgata aacctatcac agaacacttc tcaaattcag 83040
ctaagcaaat ccaaagtaaa caaagtatag atgttaatat tggtgttgac cctgcaacag 83100
gtaacttgaa cggttatgtt acaggtaaga tggatgagta tgttaatgat atgttccaag 83160
gaacttacaa cagcatgtct ccttcaaatt aagactaacc cgcttcggcg ggtttcttat 83220
cctctgaatt ttatctttat ttatgatata attgatgatt ataaagaata gaaattacag 83280
gtaacaaaat gatcatacct acttatataa cacctagtgg gggtggtgat aaactgtacg 83340
ctgatgccgt gacaagtctt acgccacaat attcagccac tcccaccaaa tatccaatca 83400
gttcgaaaac tcagattaca aacaatatta tacgccaaaa ccctatattg aacatttctt 83460
tgtttgtagg taagtctcct ttaaaatcat atgaagacag tttagttgga tatgaagacc 83520
taacacaaag accaacatcc acgcatgagg tactattaaa ctggtacaac aattcaacac 83580
agctatttgt ttacaatgaa ttttttcaat tcgattccta tgtaattacg aactataccc 83640
ctaagcaaat tgaagcatat gatactcttc aatttgattt aacatttgaa aaactgcgtt 83700
ttgttagcta tgagaggggt actttaataa ctttcatgga ccctacaaaa tctacagatg 83760
ctacaggtaa atcttcgcaa agtgatagtt cttctaaaga gaaagttcag aataagtatg 83820
tatctgatga cgttttaaat gcttacctta agagtttaag caacccaacc aaggaggaaa 83880
caagtggcaa ttagtttaat ccctcttgag cagaatcctt accgatcata cagggttact 83940
cttgacggtg aatcctatga cattgttgtg caatacaatc agcgattaat caaccaaact 84000
tccacaaatc ctaatttcct tcctgaaagt gcagatagtt ttacaatctc tattgcattg 84060
acaggacgtg acccaatttt aaaaactgca ttgaaaacta accgtgacat ccttggtccg 84120
tataagtacc gtgaaggatg ccctcaagga aatctcatcc tacgagatat tgcagcagat 84180
ggtaaccttg ttgatggtaa gttgtatgca ccagaacgtg tgagttatga aggaatagga 84240
tcgagatttc tactcttata tgaaagcgag gaataattct catgagaaca gaaatactat 84300
atcgattcac gattggtaaa cctttaaagc ttgaaaacaa cttctttgtt ccatataaga 84360
atgaatcatt cccaacaatt gccctcaacg attattttga cacagaagac cctttcaata 84420
gctatatctt tacacaacat caaattcaat tcaatgtcaa catggattct agctctaaaa 84480
taaattctag ttatgtcaca ttgtataacg ttgatgaaga agtaattaac tttgttacaa 84540
ccaattataa taacaatctg gtgtgtatcc tagaagctgg tgacaatgaa caggggttga 84600
aagaaatctt caaaggcact attactgctg cacaaaagat tgatgataca caagatacac 84660
aacttaagat gaatttagca gatggtgtag tgaatgcaaa gaatgctaag actattcgta 84720
cataccctcg tggaacttca tacgaaacca ttctacgtga tatgaacaaa gatatgaagc 84780
taccaatctc aagttttgca ggggtagaag gcaggttatt aaaccctgtt acttttgcag 84840
gaagcacaca tcaaattatg gagaagttat ctgataccct tggtgtatct tattctattc 84900
agaatggtgt gacaagtatt gtaccttacc gtagttataa aaaagtagaa gtgtctatta 84960
ttacaccaac atcaggtctt attggtaata ttaagaaagg tgtggatgat agtaagagtg 85020
gtcagaaatc tgcaagcatg gattcgaaca gtatccaatt tatgtgttta ttagatggcg 85080
ctttaaagcc taatgaaaca gtttatgttg atgatggcga cattgttgga ccatataaaa 85140
taacaagtat taagttttct ggtgattacg aaggtaatga ttggacatgt agtgttaagg 85200
cagcgaaagt tgaaggggtg ttggagtaat ggcaggagaa ggtttaaaag taacaccaaa 85260
gcaaccacct tatcgtggag gacttaacta tgctatggat catgccatag aagataaact 85320
tcgctttgct agaacaatgg taccagctca agtattaaaa gttgattatg ataaaagttt 85380
agttaatgta aaaccactaa tccgcttccg ttttgatatg gctacagaag atgagtttgg 85440
tatcgaggaa atccttgaag tacctcttat attctcatct gcaaagcgcg gcgcagctag 85500
aatgacattt cctgtacgag agggtgatgt tggactgctt ctatgctcag accgtcatac 85560
agagaatttc ctagctagtg atggtatatc tgttgtggat agtggaagtt tctctacatt 85620
gggtacagat ggttatatta actatattgg tttcatacca gaagtattta caagcgctat 85680
aggtgagagc tttgacccta acgatgttgt attgacacat ggtagtggtg aaacacgcca 85740
caagcaagat gggacaataa tctctaaaaa caattcatcc acctgcacac aatcaccctc 85800
tggcgaggtt tcattagtta atggtaatgg ttatataaaa cttttagctg atggtagtgt 85860
agatatcaat ggttttgtta tccaagtaaa tggagcagca agttcaccag ttagtgttca 85920
agcacctact atcactgcaa ccacatcact tactgttaat ggtaaggaaa tgaatgaaca 85980
caaccacgat gcaggaacat acgaagcagg tggtgaccca gtttcaggta catcaggaga 86040
tccggtttaa tggcaaaatt tgacatgttt atcgatgcaa ctggtgtaga tgatttagat 86100
ttttctaatg gtatagattt ccgttggaca gagacaatat tagaatcatt aacacaacgg 86160
ttgcaattaa ggtatgaggt ttggacaggg cagtgggggt acaatctaca gtttggcacc 86220
ccataccgtg aattaatgca gcaaggttta aataagcaac aacttgatgc agaattcatc 86280
cgtattgcac ttcaagaaga agatgtgact tctgtcaaga ttatcaactc agttttaaat 86340
aacgtaactc gtcgttatga aatacaaagt ttagaagttt acacagacgg tggattatta 86400
gaaataccta tctctaatcc ttatacaaaa actaataatt atccagaacc agttgaaatt 86460
tcagatttta cattctgtca gaaaacagac caagagattg aagattacaa taagttatat 86520
gagttcataa acttcacagg attgccagaa tttggcgaca gtacatggtg gaatacgtgg 86580
ggaggtaacg atccttactt tagtccagaa ttgattactg cgattaataa tatctatggt 86640
catgttaatt tcgacggtct ccctgattcc ggtgatagct actggtctag cgactggggt 86700
ggaacagatc caatttaata gaggaataaa atgagtactt ttccagcaac aaatagtaac 86760
gaagctgttg agttggttat cgatggaggt aatcaattac accagataat caatgaagat 86820
gcaatcactg aagttcaaac agaatcagga ccaattccat cagtaagaaa agcattagct 86880
gatacatttt tattcttgga accaatacct tggcaggatg gaagtgatga aataagtttc 86940
aaccagttga gaactttcga tggtatggta tattggtcac ccacagcaac actatctaac 87000
cctgtaccga tgggagttac acctgtggga gatagtaact ggaatatagc tccagttgat 87060
gtaagtcgtg agtggacaat cgaagaaatc aataaatctc aagagcagat agtaggaggt 87120
aatatattcc catcggatgg tacagttctc gaaacaggac aaacagttcc tatagggaca 87180
acacatttga gggtagagat tggtggggaa cctgtaattg tattgatgtc ccctgaaagt 87240
agtggtttag ttggtgaagt aacagaatca gatgctgtcg taggaggaag taatgtagaa 87300
tttttctctt acgtagaggt aaacacttta tcagatgcca taaaattaaa aaacacggca 87360
ggatttgtaa ggatattcag aagaaccagt ttcgggggag gaggtcttta taaagttacc 87420
tctgatgctg ttaatggtta tgacaagatt gcaatggata acggcaaaac attaacgtta 87480
caaatagaag ggaagtgggt caccttggag caactaggtg cagagtttag aagtgatttt 87540
gactgcctac cttattttaa ttttgcaaaa gataattatc agtttgtaac tacagagatg 87600
tcgggagtga tgtatacatc agatgagctg ataccatcga cagggatgag tttcgtatca 87660
gaaataagta gtaatgcaac ttcaataaga gatttagaaa taaaagtatt accttctagt 87720
ctacttatac ctaaagcttg gcaaaataaa gctgtattta gagcatcctt gacaccactt 87780
ggaggagggt taccctcaga tctctctggt tgtgaatttg gcccgttcga tatagatgca 87840
gaaggtgcag atgtaggttt ttattcaagg taccttacta atgaatcaag agttagtagg 87900
ataaccgtaa gaaatgcgac agtttgtaat ataaatatat tgacaacatg gtttgccaag 87960
tacgatggtc ttgtatcgat gagagccaaa ggtaaaggta tttctctggg gtatcctttg 88020
ttctccgaaa caggagattt ggcagttaat ggtatagaat tcgaggcagt tcgtgctaat 88080
ttttcaggac aatcaacgga taatttacta aaatgggtgg atggtgttga tgtaagagct 88140
aacgctctag atggagctgg ggtagtgata gctactaatt cttgcaattt ccctacatta 88200
caagctgaaa aaggggttgg agtgggtatt gtagatattt cagcttttaa taattccttt 88260
ggtactatat acacagaagg taattgctcc aacatgacaa caggtagagc tgatgttgtt 88320
ggtaaaaata caggtacagg taaggttatt caggttcaaa atgtgtttat tggttccaca 88380
ggagataatg gttggtatct agaggataac tgtaacgtag atgcaggtat ggttactagg 88440
aatagtgcag ataacacctt ctttgcagac ggtaaacaag tcatcatgag aaacgctaac 88500
agccttgcga acctgaacca agatcaggat gttcttaaga gtgaacaatt aacactggct 88560
tcctttttca acgtaaatct tagatacact ggtgaattcg acaatgcaag gtttttcacg 88620
gatgaccctg tatctttccc ttacgtagtg gtgatcccaa gaaataatta tacattagca 88680
tcaaacctag ctattaatat agatggtaac actacaagaa gttacggtac agattttgta 88740
gctgatacac ccgtagttat aaggcattct tctatattag aagggtctca taaacttaac 88800
ttaacagggt ctactcctgt agatgatttt tttgctgatg tgtatgtaat gcaacgaaga 88860
cctgccacag ggttcagcgt agtacgttaa tatcattaac ccgcttcggc gggtttcttt 88920
ctacctgaat tttaacctta tttgtgatat aattgtttat tatattaaac aagttattac 88980
cgaggaagaa taatggcaag cggatttatt aatggtattt tccaaagaga taccttagca 89040
gatattatcc tcagtatcga aaatgatgtt agggtgacat acaacaaccc taaattcagt 89100
atagaagata atgagaatat tggtcagtta ttaaaaatga ttgctggacg agagaataac 89160
atctggcaga caatcgaaca ggtttataat tcatggaatc gaaatggtgc ggaaggttta 89220
ttcttagatg agatctttgc tttatcaggg gtgttccgtg aaaaagctac ttcaggtagt 89280
ggagatgcag ttgttgaaac aaattcatca gctatcgata gtacaagtgt aggtatcggt 89340
acaatcttta gtggggagaa tggtggacaa tatgctgcaa cttctacaca atttgtaagc 89400
agtcgtgtaa cagcgtaccg tgtagtggga agtaatattt cacttgctac ttataatttg 89460
tcaattgaag atttaagctc aggacaaatc ttttctcaaa gtttcacact ttcatccaac 89520
acacctacag cccgtctaaa tttcctaaac agtcttaaaa cattccttga atcagtgaat 89580
ccttctgaaa caaatattca attagataca gataatctaa ttttatattg gggttttgat 89640
gaagcttacg aactaaaagg tttagaaaaa acagttaagt ttctttccac gccaagttta 89700
ggaaatcgct actcacttat agaatgtgtt aatactcaaa caggttttaa tccattaggt 89760
gttggtggta ttgcaagtat cagtatacca ccgttaggtt acgtaagtgt aacaaactta 89820
agcgaattct caagtggtac agatgtggaa acagatgcag catttgttga aagagcgaga 89880
agtgaagttg atagtccacg aagtgctaca agatcagcaa ttatcgcagg tttgctagcc 89940
aatgttagcg gtatagaaaa gattaaattt aataaaactg tggatgcagg tattgtaaca 90000
gtggtaccta ttattattgg tggagagatt gcagatattg cacaagaact ttatcgtacg 90060
caaccaatta ataatgtcta ttctggtgat atccaataca cagttgacac agaagatgaa 90120
gatcaagaaa ctatcagctt ttctcgtggt gttcaacagc aattaagtgt ccgtgtcaag 90180
tataaaacta ccaataacac agagttatct acttccgaga aaagcatagc gacaaataat 90240
ttattagatg tatcagaaag ttggcaatta ggtgataaaa tatttaattt ctccctaatg 90300
tctgcggtaa gttctgcagt tagttatgga agattcaacc agttgattgt agaagttaag 90360
aaaatagaag atccagattc atcctattcc aatgcagatt accaagcagg tagtacagaa 90420
ttaccagatt taatctctaa caatattact tttgtacagg agattaacta atggttttac 90480
ctgattctaa cagacttaaa tttaatgtta catttacaca agatggtttg agtgaactac 90540
cttacaaaca aactcagcga gagaactttt ataaacttgc tgagctgatt actaatcgtt 90600
taaataacat ccagaaccaa gcagtgtcgt tagcctactc ccgaatttta gatttagcag 90660
aaggtgatat gttggatgtc atagcttccc actattttat agaacgtgaa ggtaaaagtg 90720
atgaaggttt acgttcagct ataaaacttc atgcactacg acaaaacaca gaaccaacac 90780
gtccagaaat agtaagtatt ttaaatatac tgacagataa tggttttgtt aagatttata 90840
aaggtttaaa taattatgtg gaagttgtta ttagtgtgga ttgtttgtca atacagtctt 90900
tatctgacca gttacaggac ttattcccag ttaacactaa tttaaaggta gcctctgttc 90960
cagtagggtc aaaacctttt ggtgttggta gtattcactc tataccttca aataagattg 91020
gacctttagg tagtgtccat gactctatta tagatagacc gaacgtaacc tcagtgacag 91080
ttattaatga tgagagagat ttataaatgg caacacaacc aacaaaccct atcatcagga 91140
tagcggagaa tgatgtaaat ttaccaagca caggtcagcc gaataagaac gaacctagtt 91200
cgactttaca gtctacaggt tatgataatg atcaagttgt aacagcagaa gaacttaatt 91260
atatctttga taacttctct gagtggttag attacctagt attggaagat agtgacacta 91320
atactagaat aaataattta gaatcaagaa ctattacagg tggaaatggc ttaacaggtg 91380
gtggagattt aagtgaaaat agatctatag ctttaggtac accttcctca ttagatggtt 91440
caacaactaa ctctgttacg acaggttcac acacacacag tttaaatatg gcgagccaat 91500
cggaagctga aactggtaca gataacacta aacctgtgac atctttaaga atacaccaag 91560
ccgtaccttt tacattcaca ccatcttcaa ttagtggttc gacagaatcg acaaccctac 91620
ctaacggttt aataattaaa tggggggaga caccttctat aggagatgga ggagatacta 91680
tagtaacctt cccaactccc tttcccaacg catgtttcca tgtaggtact gaaatcttaa 91740
gaaacgtatc aggtgatggt ccaaacgcat acggtacagg tgttactaat aaaacggcca 91800
gtagtgtaac tatctctttt aatggtacag gttccgtatc ttccgtgata ggttggtggg 91860
caataggcta ctaaataata acaataataa ggaaaagtta tggcttgggt agagtggtta 91920
aagatatttg taatgattgt aaccgtattt ggtgcattat ccacaccgtt tgtttatata 91980
tggaaaaggt ctgaaaggga taagcaagat aattcagaaa gtattaaagc tttaacagag 92040
aaagttcaga agcatgaagt ggatattaca ggattggata aaggtaaagt aggtcatcac 92100
gagatgcaag ctgcaatcca aagattggaa tcttcgacaa ataaccaaat tcaaagttta 92160
cagaataaga tcgacagtaa tcataaccag tatcgggagg aactcacacg aaatatgagc 92220
gacctcaaag attatatgaa ggatatgatg ggtagagata ataaatagac gaggagtgtg 92280
ggatgtggta tttgatatta tgtttcacac tctttttgtt tttatcaaag aatataattt 92340
ctaataaggt aataccatta ttattcacag cttatctgtt taggttagaa tttgcatcaa 92400
ctttgacatt gagtgaatat gtttggtgga ctataagttt attacatcta ttctggttct 92460
atacatactt aaattttaaa agagtttacc ttgttgacac gataattgtt tcttgtataa 92520
aaatattaga gttggtgata attacatttc catttgtaag cttttattta ccagaactta 92580
tatcacaaca gttatttaag ttagataata tattcttatc gggaatagta acttgcttgg 92640
tgctaagaga atcaggttac aacataaaag ttgatgtgaa gaatatgaga gcattctacc 92700
tactattcgg ggttgtaatg atgcatgtga ttgcttatgt attttaggtt tgaaattcag 92760
atatgaatat acccgctcga atgagcgggt ttttgttatt gatttatata atgtttctag 92820
aatgggatat cctgtcgttt agtaataacg ctacttacta cctacacctt tacgtgttac 92880
tataagtttt cacctacagg tcggatcata tcatcatctc agtgagatgc cttgcacttc 92940
ggatgaccaa aagcttgtct atcctatcgg gtatttcccg tgacctctga acgttccctt 93000
attaagagct tcgctgctga ttaccaccat ctaataatta aaagtttatt atatcaacaa 93060
tcctttaact accaagctga ggtttccagc aattcacaaa gttattcaac taacatcgct 93120
gttagaggcg acaatcattt atcgtcaaaa tcaaatggtt ctggtgaaga ttctggttct 93180
tgtggaacac tctgagcttc cttctgagca gggttacttt cttgcgcaag tgtttgctca 93240
ggtttatcac taacaccact ctgtgaagct tgtggtgcgt tatttgaagt attatcacta 93300
ccaaaaccac caagagcttt acacaagttt gtatcttccc atttcgtacc taaccaaaag 93360
tcaggtgctt tcacagcatt aggttggaaa cttgtagctt taggaagaac agctttcaac 93420
tcacgtttat tagaaataat ctctaaaatt tgtggatcga aagtttcttg gttaagcatc 93480
acagatacag gaacaatatc acattcgggg atctgctgtt cacgagtaac tttaccaaca 93540
cttgggatat tcaaatcaac aatacgagaa gttgacttca atacagcagg gaacattcgt 93600
tcaagagttc catcatcact acgtttacaa cgaacttcaa agttaaggtt tagtgcacca 93660
ccaagtagtt tatcgaaatc ataaccgctt gattcaaata catcaccaag actcatgttg 93720
ttagcgagtt tttgaatcgg gttatttggt gatagcttac cagtttgcca gtgagggtta 93780
aatcgtaaac tcttaccaaa accttcccaa acaatctcct tacttgcgtt acgacgagag 93840
aaataaccat taaagctgat gcgtagtggt ttctgaccaa gtttgtgcat tgactcaagt 93900
ggatgtttag tccaatcaat aacaatatta ggaacatcaa atgctacata aatttcttgt 93960
gtaggacgtt caggtttgta ttgtttacgt ttaccatcaa cagtgcggaa gtagttgtca 94020
ggatatttac gaacatgctc tttctcagct tcactatacc cttctggcat attctctacg 94080
ccatgacctt tcttaccatc ttctgtgcca gcttcaagtt tagaatcata ttcagaatca 94140
ggttgaggtt gtagaccaca atctaggaag aagtttgcaa tacctacttg agttaatgac 94200
ttggtgaaag tgtttgggat tacagcacct tgtccatttt tagcaggtga ctcatctact 94260
tcaaacaaac tccactggta ttcgttccaa gcttgccatt gctcttgaga tacatcatta 94320
ccaccgttac tgccagattg tgtttgtgtt tcaaatttca tatattttcc ttcaattaac 94380
gttctttaca gaacaaatgt tatcaccaat tgctatacag ctttgaatgt taacatcttt 94440
tacaagacaa ggtattcctc cttatgtcac atctctatga cgaaaagtac ttgttttcac 94500
aacataaacg taattattct atcaaagttt tcatcgttgt ttaatagtga atattaatat 94560
tctcatgttt agatttgaat gtcaaccagt ttaagctcta taagagtaca ttcataatct 94620
tcttcattat agtatttctc aaacaagtct tcctcttcca catcagggaa cattatcatt 94680
aaattattct gaacaaataa acgttctgac ataaacttac ttttgtgtgc agtactgatg 94740
aaaacatcat cagagtgttt atcatgtaca acctaatatt taggggagta tgtttgttct 94800
ttatgcatgc aatacctcct caaaatctgc ccatgtatat ttgtatttat ggttgaaagc 94860
tttaggatct ccaccaatac ggaccatttc atcaccttgt acaagtatcc cattcttctt 94920
actacaaatg tactcacctt ctacaacact tccgtagatg acatctttca ttccagagta 94980
gttcccagct tcagagcttg tattttctaa aatcttaaac ttcacactac cacctacctt 95040
tcaagtacca aggtttgttg tgtttacgat ccaaccaagt tttatcatac ttaatcttct 95100
taatatgtgc aatgatatct tcattaaaat ttgaaagctt atcaataaca atactatcgt 95160
ctaataaaca tttgtccgat agtgtgtacg ttggagtttc atcttctgtt aaatcctcac 95220
cgacatcttt atgaacaata accaattcac ctttagcttc aagtttaagt agttgttcat 95280
acacaccttg aaaagattca gatataccac caacgattaa tattttaggt aattcattat 95340
tcatgagggt taccacttag tgtagaaatc ttctacagat tcaatacata acaagtcttc 95400
aggttttgta caagaaatta cacaaccatt ttcaaggata actttattct gtcgtgaagg 95460
gtcaaaccct ttcacagaat agaagtgacc acgtttagtt accaccacgc atccgagaga 95520
tattagtgaa ccgtttttat ctttgtacat taacactcct cctttaaagg aaggtcattc 95580
catttccaac aataaccttc tattacatca ataattgtat tcattatttc atcatcgtca 95640
gtactattcc aaagcttttg cattgtatca gatgaagaat cttaataaat aagttaataa 95700
aatgttggcc gtatctatat gatggaactt tgtcgtgaat atcttgccaa cttttatgaa 95760
aatcttgata tgtgaatggc atggttattc ctcctcaaaa tatccaacat cgtttaggta 95820
gttcctagct ttaatcagtg tttcaaaatc ggcataatat ttcttgtacc taccatcaca 95880
acacatagat aataaggtat catctaatgc tttaggtaaa ttaccattgt aaatatcttc 95940
aacaaggtca ttatattctt gatttaaaga gtttacgacc gccttaacaa atttgtgttt 96000
catataaatt ctcctcaata atttcaatat cacaataaaa tggcgtactt agtaagctgt 96060
taatcacact cttagctaga acacgtttac gattataaca gaaaccattc tttgtgcaac 96120
ctaatttact atctttttcg ctgctaactt taatttcgaa aacgttatgt tttcgaagaa 96180
cactgtgtgc ttcaacatta caatgttcgt gagagttgat atctttgcat aacatattaa 96240
tcctgtcaag cggagattga ttattgcaca cccgaatagt ggtgacgagg ttggttttca 96300
tttgttaatt accgagtaag taatatctaa acaattttca tcaacccatg tacctttgct 96360
ataagtactt atgataagtt tacctttatc ttcagataaa ccagactcaa aaacagcaat 96420
acctagtgta tcatctgaaa ggaaaattgg gttttcgcta gagaagaatc tccaagctgg 96480
gacaccaaga atatctaaaa atttcttcca aactagaacg tctgtggact ccaatttggt 96540
attgaagtat ttatcgttat ctacatacag cacagttaat ctcctttaaa caataatatc 96600
aaatcgtttt ctgtaactac gtttcacaag ataaatcttt ttgttacgca agtcaaccct 96660
tattttatca aaacctgtaa ttggaaaata agttggtctg atagggtgat tgttcataac 96720
acgagatcgt cgattgagaa aaccaagtgc atgttgaaat ttgtcatcgc aatcaaagtg 96780
aatcttggtt gtagtgtagt cagtgacaac taaagcagta ggtaacatgt accttggtga 96840
agctttgtaa cgacttgtgt aacgtgtggt tgtttttgtg atcataactt atcatcttcc 96900
aattcttcaa cagtgaaacc ttccaagtca aagaaagtta aatccttttc agcagcacgt 96960
ttagtttgat aaatacaggc tcgtgcccag tgaagtttgg ttacaataca accacaagct 97020
tcccctgcaa acatctcacc atcttcattc attaatacat acatgattac tttctccaag 97080
tcaagttttt aatttatagg ctagtttaac ataggtacgg tggtcattag ggtttccata 97140
tactacgcct ttcttaacac aataagcgtg accagatgag agtattatat aagttgcatc 97200
tttatcacat ttttcaagaa atttcttcaa atacaaacct gtactgttga cgtcactatt 97260
acctgtgcaa tcaactttat cttcacgttc acaccatctt aggtgacgtt tattaaacaa 97320
ataaggtact gtcttacttg acaaatgatc cttaccgtta aagttggtta ccatcggaaa 97380
tcctttacct tttctccttt tcatataaag agtacaaaat tggtgcgcat gtagatacgt 97440
taaatcaaac gctacagcaa tagctcttac ggtgcaatca ttattctctt taagctttat 97500
tcgttcgttt ctaaataatt cttcagtatc aataactttc acaatctatc cctcaacaat 97560
tttaatcgta gtaacaagtt cacctttatc accaacaaac ataattgaat gcttcttagc 97620
tttgttatca atgaatatac ggaacatttc acccattgtc aaggaatgat tccaagtttt 97680
aatttcagac aacacacctt ggaaaccttg cacatgtgaa attgaatgag gttttggttg 97740
attaccataa gtccactcaa cacggaaatt ttgtttacaa gcgtaatggt gttggttcat 97800
attgtatagt tttgacataa taaaacctcc ctgtttcgtc gatgtaataa atatacatct 97860
gcagagagga tgtgtcaaca agaaatttta gttttatttg ataattcgcc atttatccgt 97920
atcaaacatc tcataagggc gagtgtaaat acttccttcg tcagtatttt ggtagacaca 97980
accaagcctc cattcaccag atgagtcttt gattttgaca ttgtggtgca atactaggta 98040
aaaggtgtct cgtggagtgt agtaaagctt ggttgctgtg gtgatgttag tcattggtgt 98100
ggtcctttag gttgaaagag gatgagcatg ttatagataa attacttccc tgttttataa 98160
tataagttcc gttattggtt aatatatcaa aagtatcatg taaacctaca gactctgtat 98220
tgacctcttg catagtgata tgaccattct ttaacatcct taatgtcaga catttatggt 98280
cattaggact tttaaatcca gaacttaccc tcttaccttg taagaacata gctaacataa 98340
ccgagtcagc tactgtacct gaattttgga caatagtggt ctttgtacct ccaaagttat 98400
cccgttttgt atctccgtca gctaaccaaa aattatatag atattcgtag ataccttctt 98460
cactgtaact tagtatatgt ttacaccaat ttatttctga cttaggtaat ctctcaccaa 98520
caactctatc cataaaggat ctgaattcac cacaatggaa gtggtatttg tttactggtg 98580
aagtctttac tccggtgttg tcctcatgca aactataagg tagtccaaca gaagcaataa 98640
cctgctccac atctttatag aatttatgtt gtgcttgtgc aatcatacct atgacacctc 98700
tcttatttcc aaaagaagaa gatgtccttt ttgtatcttc actccatcta taatacccat 98760
cagataatag ccaaccgata aaagcagcct cttgtggtgt aacagttgaa ttcccacctg 98820
agtacttggc agagcaaaga atattaaact cttgagtaat ctctggaata gtgaatttat 98880
gaaaatactt ttctctctta caacctttct tagcccacat ccttttccaa ccgtaccata 98940
actgatcctt cccacaatta aactcagcca acttatggta tagttttata acctccgtat 99000
tatagttttt ggttatgtcg attacagtat ctaactctaa gaaacctcta tctatagagt 99060
aagatacaca ttcatcacct acaacaatat cacctattag tttccaacct tcttttgtta 99120
atatttcggt ttctttacca aacccaaaat cattcatctt atatttcaat cctcttaatt 99180
aataaccctc cgaagagggt tataacttca attagtgagc acctgcccaa ccttcctctg 99240
gtgaagccat caagtattca cctgttatat gaactggaca cttaagtagt ttataagcat 99300
cctcaataca cttaaccatt aattccccag cacgagagta agcaataccg acagagccat 99360
cattaagaac tttagtgttt ccagataata tgaacctacc tccctccgtt gcctcagcca 99420
agtcttgagc gttaatgata tctttcaact gatccatctc aatactgtat tcttcgcaca 99480
tctctttagc tgttttataa ggtttgccct tagatttatt tttcttagat ctagctacat 99540
catcaagaat tgtttcaaca aagtttttat ctttaaaacc cgtttcatat cttttccaac 99600
gaactaaatt gtctggaacc tgtagctgat actcatcctt ttaatttcag aagcgttact 99660
ttctttccac aatttcttgt gtaattggac catatcacga tctgatagtt cagatcctcc 99720
gcttttcgag attcacttga atccctacga acaactatgt tctggtctct gcacaccttt 99780
cgatgctcag gattgccttt gccactacgc agtaaggttc ccctgaatta acggagtttt 99840
tcgacacacc tcacgatgtg aagccacaat gagtttatgg tagtaaattg tacgagctac 99900
acctttatct aatagacctt cctctaaagc cctttcatgc cacagtatac cagctaggtc 99960
catacctatt gcaccaccgc tctgtaagta gcaattcaac aagctgtgtt tggatcgtgt 100020
ccatatctta cgaccatcta cagcaatgat atactttttg ccggatgctt cccaaacctt 100080
ttccagtgct tccttacgct tcttcaagcc gatgtttccg ttccagaaag cttctattac 100140
cttctgaccc gtatccttat caacacctaa catagtagct attttagggg ctgctgcacc 100200
atacataatc gatatattca aacaggttcg ttactcctgt ccagttctct tatgaacttc 100260
tctatgtttc catagaagac tagactatat ctccatctct aacttaatac tgagatgccc 100320
accgtttcga agtcacttga cccctactaa ttagtcgtta cacgttctct tacgagcttc 100380
gctcggtatt acctttaact taatattaag gcttccaccg aattagatgg gttacagata 100440
agtatttcta cctacctagg ctatacaata accatatgtg atgcctttac cttcttgtct 100500
tgttacctct ctacctgcag cagatgaata attttctgcg tttcgagcat gagcatcccc 100560
agactccatt atacgaagat attcccctcc atcaaaatca taagctgccc acgccccgat 100620
catcccttcg aggttagacc catcaatacc aatctgccaa taaccttcag gaactgtgaa 100680
taattccctc atttcatgac ctaaaagagc atcagtgccc ggaatatttg ctactacgga 100740
gtgttttctc ctattcgtgt tagttaatcc agaatatcgc gctggtaatt taccatctac 100800
ctttaatctt ggatgattta accagcctgt ctctttggac tcatcaatag ctttaataac 100860
tgaacgccta ttacggagtg ataaccactt aacgatctta cctgccatct caccatcgat 100920
cttagctaga ttgggacata actctccacg ttcatccttc agtttaggtg atgtggtaag 100980
aaacctagct tttttaacta cctttttaaa gtctggatgg tttctactgt tgattttatc 101040
tatctgaact cccatttcct gattgatata ttttagatag atagactctt tagtatcttc 101100
gatatacttc caacaagctt cctctatttc aaagtcaggc ttattctgtt tgttatcatc 101160
cctagattca tcttttgttc tgaacaaggt tggaacccaa ccaccctcta aaacaagcca 101220
ttcctttata tcagcttggt tagataactt cataggctct ttaagaaact tctcagggat 101280
atactcctta cctagtaact ctctggcttt aacctcatct tcttcagata agactttaag 101340
tgatgactct ttctctctct gagatctgat aaagtctgcc atagaagatt catcctctac 101400
accatgattg acacaatacc ttttacctgc cacagataac tcacctgtct ttttaaaagc 101460
tgttttaggt ggggctataa atttagttgc ttccctatta acatctatac cgtaatactt 101520
ctcaataaag ttcaatccgt gatgggatat attaccgttc ttgtcaaaag gattagccgg 101580
aaaattaggt tgccttgatt taggaacatc tttaggtgga agtcttggtt ccacatcatc 101640
agctatctcc ttcatcattt ggtcaattct aaccacaagc ttttcagcct tatctatgtt 101700
gaaaacaaca ccctgttctt cctgaagttg catcaagtga tcagcctgaa gattcctttt 101760
aagtgggttc ctccagtcaa caccaagatt cttcccatct tgcatctctc tgatcagata 101820
ttgccattga agttcattaa taataacgtc ttcccaaaca cggtcaacat acttccaaag 101880
gggtaatcca cgccaatctt cgatagctac ctttttattt gctaccttcc agccccagct 101940
ctcaaggcta tgtggaccaa tggttttagc cttaccacct aatggatttt taaccttggc 102000
aggacatcct ctaggtaaag gtctatcagg gtaaagacca cgagacatac ttaatgtgtc 102060
atagacccga ataggttttc cgttaatagt ttcttctgga atttttacat actcagttcc 102120
aaagataaac ttgaaagcta acatatcgta accctctaag ttttgacaac ctattgcttc 102180
tggttcatca gatatccaat tattgaattc tttgaaatct ttaacggaaa gatttacccc 102240
cttattttca gcaaagtcct tagcttcatt aaattctgga tggttgaaat ctagaaataa 102300
tttccagtta tcctttccgt attccttgaa aagaagacaa tgaaactttg tcatatgatc 102360
ttcaggtggt attgatttac cacatagacc atcaccttca gtatcgaaga tccataatcc 102420
tttcatactc tctcctctta aaatggttca tctaaatctt catctgtttc tgtaaccaaa 102480
cctgtctgct caacaaaaga cggttcttga taacttttct catcaacact taatgtctta 102540
acaggctcaa tagttatctc agtaggtaca tcagaaaagc agtggacaac ctgaccattg 102600
tgtttgtaac actcaccttc tacttcccac tctgatgcat ccacataggt tccatcatct 102660
ttctgccaaa gagtatcagc tacacccagt acagaacctc ttcgattctt agcgagaact 102720
agtctaatac gacctctgct tcggttaggg agttcttctg gttcaagtag gataaccacc 102780
caagacaatt gttcaagtgc agcactgccg cgcatatcct ccttacgtac agggtagaag 102840
aaagggagtt gatcacctgt ctctttatct tttggaggtt cgatattctt acgtttcatg 102900
tggctgacac caagaatgaa cacaccatat tgctgacaaa aagctgcaag ttctgtcata 102960
ataatatcta actctttcac atcgttacct gtacgcatac cacttacaag catagtatag 103020
tgatccagaa ggaaccacct acagccaaaa gccatcatct gtttaagttt actaatgagt 103080
tgatcgatac ttagtgaccc gaagtgatca agaatcattg tacaattctt ttcactccat 103140
ttttggtgaa ccttttgatg atcttcctca gaaatagaac cttcaatgtc ttcaacgaac 103200
cgcttagcat tcaaccctag atccatagca tagagtgaat taaggctttc atcaaaacct 103260
tcctctaacc ggattatacc aatcttctca tcttcttcaa agtctgctaa tcttttatta 103320
ccatcttcac aaacctttaa atccttatct ccgaagattt tctcgtcttc tggttttatt 103380
ccgtacataa ggtaagaagc tatatcaaac tctatgtccc ttgtgattgt gcttttgccc 103440
gcaccactgg gtgccgtaag tgaccagagt tcacccttaa taggggattt tgttttctcc 103500
tgaagtttct taaggtggcg tagaggaata ccttttttct tcttcttcct tagatccgct 103560
acctttacat ctgctgcgct aagtattttc tcaggtgaga attttctcaa gttccaagta 103620
atctccttag caaaaccctt ggggtctaag gcagcccatt gcctgcaatc cttgactttc 103680
tctggaaact taactacatg aaagttttgt gcaagcaaga aagcagcaac atcttccgta 103740
gcctctttgc cctttttcac acctttgact ttctcaagtt ccgtagcctc atctgaatcg 103800
aataaacaaa ctatttcagc aaaagacctg ataaactcct cattgtgtgc agtcgataaa 103860
gctgcattac cagcaccgca gtttaagctt actacgtttg gttcaatctt tccctcgtat 103920
ttagtacctt tcagggaatc aagcaaggct ctccttgtgg atatgcaaca gccttcaccc 103980
tctgtataat agattttacc tttagcatta ggcttacaaa catgttgtcc aaacaattga 104040
ctattaactt tcacaacacc aacaacagta aagtgtccat gttcctcttt gtctttagtc 104100
caatctctac gtttgtaacc tgttaattta ccatcttggt tgtaataagg gaaatatgtt 104160
gcaaccagtg ttttaccatc ctcttgagaa tactccgatc tcacaccata aaactctgcg 104220
tcctcttgaa gaatatcctg ctgaggaaca gcaacacagg gaaaagtctt tacttcttct 104280
actgttaaag gttcctcatt ccgataatac ttttggaaag ttcgtccttt ctttgcactt 104340
actgacatcc accctccttc aaactcgctg atgcttgaca agccaaagca tcagctctct 104400
cattattcaa atctccattg tgccctttta cccataccca ttcaacagtg tgaatatggc 104460
acaactcatc taatcttttt atcaattcaa cattcttaac agcgccttta tttgctgtcc 104520
tccatccacg agatttccaa cctgataacc attgtgtcat agatttaatg caatattgac 104580
tgtctgtatg taagataacc ttacagggtt ctttcaaaga tgataatgcc aatatacaag 104640
ctgttagttc tgatacatta tttgtacctt caggtatagg atgcgaaatc tctttcattc 104700
taccgttaaa cattaagact accccagcac caccgtgata gcctcctcct tttgccttga 104760
tggatgaccc atcagtgtac gctattatct gtttaatact tcacctcaca acctttataa 104820
tcaggatcga aataactaat aatggtggta atcttctgat taatatcttt caaatcatca 104880
agtgttaaat cattaacttc acaccattca ggttcttcaa ctccattata aaccatgata 104940
tcaaacaaac aactgtgctc tgtaatctcg ataccttcac catgtctatc aattaagtca 105000
tattctgtac tcatactcac tcctcctttc ttacgttgta agaaggttca tattctatct 105060
caacatagaa aattttctta caaacatcgc actcttgttc accttgatca gtttcgtgac 105120
aaccagtagc ttgatactcc gtatcacaat gtgggcagct ataatcccac caccagtatt 105180
ctggatcttc atgtctttga atcatacaat gtcctcacat cacaacaata tcattaatga 105240
tatcagatgt atcccattca gtttttacat cataacaaga attcaatgtc ctaattaaac 105300
atttactatc ccctacagat agaataacgt aatattcacc atcgacatca ctattctctc 105360
gaacctgccc aacttcaatc tttcgattat tcttcatctt ccacctccca gttatcacta 105420
tctttcaaat aatgttctaa tgctgcacga tgatacttta attgttcaat atgaaaagct 105480
agaacataat tgctatctgc cttacacaag tctggacgaa tcgcttcaaa cccttcatca 105540
atgtgattat atttctcaat attccatcgg tcactgaatg ttagtttact cataacttcc 105600
ctcttttctc ctgaaacctg tttcatctcc atgacaaaca actacataag ttatatcacc 105660
acgcttataa ctaaagcagg gatattttgc ataataatgt ccacgttgtt tgtcactaat 105720
cattttactt gtgaatactg tgaatgtttt gtggagcttg tctttactct ccataataac 105780
tttctccttc actccacaaa tcaaagtatg tcaaccccgt tgtatctaac tttacatcat 105840
ccaccaaact tttgcaagac tcaatcgctt gccacacaat tgcatctgtc acaaagctac 105900
tatctcgttc accaccatca gtatcaagca caacgacatc cagaatttca tgttctccgt 105960
acaaatcagt aggacaactc gattgaaatt tatcgaaagt tagtggtgaa gtgtctaaat 106020
attctgccaa aactgtaaat gtttcaccat catgtttgtg tgtaaattca atgtttttaa 106080
tcataaatta ttcctgttca ccaaataaat ctagctgttc ttcctgtgga aaaccttcct 106140
ctgttcctgt ccccttttca ccattgcgcg ctaacactct gccagcttcc ttaacagcag 106200
catcaatgat aaaactttct ggtgaactat aaccagcttc ttctgcagct acttctaata 106260
gtgctacaag ctcccatgat aatccgcctt tttcatctag tgtagtcata ttaaatttct 106320
cctaaatcaa tcagatacaa attttcatct tccgttgtaa acgtggttga ttcaacatca 106380
atttgtttat tacggatgtg atgtggtgat gttgtgcaaa tgtaagcatc atagttaact 106440
tgctcgttat cacatttaca cttatcaaag tttagacatt gttttccttt acacatgttt 106500
attctcctca ccaattacta catgaagaag gtggtcatga tcaatgaaat agcattcata 106560
tgtccaaacg tgaccatctt catcgttcca gaaatcaatc tcatatcgac catctgaaaa 106620
ttcacagatg aggaacctat cacatccgca aagatgctct gtaagaatac cttccatctt 106680
ctcatggttg taaagaattg tatcccaagt taagttaatt gttagtttca tatcatttct 106740
ccttctcaaa ttcatttatc atttcaaaca actctttata ctctccttga aggtctgtgt 106800
caagacttgt tagtgttttc aacgtggcaa tcaagtgtgt caccaatcgc cactgtgctc 106860
tctcacaggg atgattatgg cacaacctct tgtaagtgtc aatctctttc ggcaactgct 106920
tcacaacata atctaagcaa gcacttttca caattgtatc tttgtgttgc atagcattac 106980
cctaacttct tacagttacg catcaaagat ttcacaactt tactatcgcc tttcgtgata 107040
tgatccaagc cttgttgaac atctttatgg actaagatta catctttctt tgtgataatg 107100
tcaactgttt tatctttcac aaacaatgca cggttttctt catcaagagg taatcctgaa 107160
attgtacaaa agttgcgacg atttaaatca cggtactctt tgaaacttac cccaaacact 107220
ttaccatact cttcaaactg cttacatgtt tgtgtgaagc cagaagttag ttgcatttca 107280
cgtttctgac gctccagagc tgtctctcgc aagagtttat tgttatcctt aataacctta 107340
gctttcttag ctaaaacatt ctcacgagct ttacggaaga tttctgaata ctctgcaagc 107400
ttttcatccc agccaacttt catacttaaa gatttctcaa tacgtgtcaa taaaaacata 107460
tcattgtgag ggatattctt tcttgattta ttactctcga taaacttgtt cttaaggtcg 107520
ttgaccttag aggtacatag agccacgttg ttttctgtgt atccccttgt gttatcaagc 107580
cgatcaatag ttggatagtt aggatgatta gctccttggt taaggacaaa ttcttcacct 107640
gtgtagaaac atttcatatt gggacgagca cgtagcaaag caatatactc ttccttagac 107700
aaccccattg taatcaaacg tttcttacaa ctttcaactt tattgtagta agctgtttca 107760
taatctttct gtgtgaagaa cattggtgat tttgtatttg acatatcgta tctcctatct 107820
gtttcgataa gcaaacttta aacaacaacc acactattgt caactagaaa acgaagtaaa 107880
atttaattta tataatttca aaattgttgt tgacaaaggt actgtgtcgg ttaataatga 107940
gcacatcgaa acgaagaagg ttgtatagga gaaatattat gactaagatt atcagcgctt 108000
tccctgcctg tggaaaaaca tatatttatg aaaatcagaa agattttgga attacagttg 108060
cagacagtga ctcatcaggt ttttcatgga tcgaagtgaa cggtaagaaa gagaggaatc 108120
cagacttccc tagtaactac atagaacata ttaaaagttt aatcggaaaa gtagattata 108180
tctttgtcag ttcacatgat gatgtgagag atgctctaga tgaaaataga ctaccatata 108240
tctttgtaaa acctgatttt aacctcagag acgaatggat cggtcgttgt tggatccgag 108300
gtaatgatga agggttcctt accttgataa agaataactg gcacctttgg gttttaccta 108360
atgacaatag gtttatgtgt aaaggtgtct ctactcttag aagtggtgag tatttaaaag 108420
ataaactgca ttggtttgaa actttctctg gtgtttaagg agaataatca tgacaaaacg 108480
aaacagtgat gacgtaagca tcttgatccg aagtagtgaa ttgttatcag aaatgcttga 108540
cgagatactt acagaaagct atattgctcc tgaaacatta atcaattatc atgaaaactt 108600
gatgaaatgt aaacgagcag ttaaggttat taaggagaaa caggaatgaa gttactttca 108660
ggattagagt cagaactact ttggatagat aacaatccgc aatattaccg tgacaagcgg 108720
catcaagaac aagtgaagag aaatatctat acacggtata aattgaatga tatgcttaac 108780
aaacttaatc gtgttttgaa ataaggaatc ttaatgaaga aagtaatctt tacaacaagt 108840
atgattcgaa gtggaagcgg tatgcttgtg tctgtcgatg aagataataa tttcaatgac 108900
gctgtttttg ttgcggtcaa caactatcca gcttcggcac tctattgtta ttttgttgga 108960
tctgaagctg taagtaacgg tagaacattc actgatgccc aaacatcttg gcaagagcta 109020
tgtgagtatc ttggtgcaac tgaaatctac ccaattaaag agcgacaact caagcagtgg 109080
tttggtgatg aatataagtt gaaacttgcc gaatttaaag ataatcttag cgagacaaag 109140
atgaaagaac gtgaagctaa gaagttgaag agtaagaaac aaagtggtgg tttgtggctc 109200
aagggtgctg gaaaatattg gaactaagag gattaatatt atgattagta aagagaaatt 109260
gttaaatggt tacattgaaa atgaccaagg agagttacgt caactatttg ttgatgcagc 109320
taaagagtat ggttacgagg ttaccgaagg gattgattgg ttggattggg aattcattta 109380
tgtggacgaa catttcaaag aagtcgccac aggtactaaa gttgagagag ataataaact 109440
cacacttgaa gatttcgtag atacaccatc agaaacaacc aaacaaggac aaatctctgt 109500
cccgccgaat aaagagtata ccaagatcac agcagcagat atccaagggt tacgtgatgc 109560
atcacaagat gacgtattca aacgaatttt gtctatcgca aaagaaaata atcttttcat 109620
ccaatttgat gggtttacac aagatgaggg tgatactatt attgttacca agcaaggtag 109680
tgatactgag tatgtgattg agacacaaga acaattcaat cagttggttg aaagttttaa 109740
tgtgctagag aagtttgaac gtaaataatt aaggagaaaa ttaatatgaa gaaacgtact 109800
attcaaaaag taattgaaga taaaatgtta gattggatga atacacttcc tgtggaaatt 109860
caagagtatg taggaagtaa gatcgttgtt acaggtggtt gtattgcaag catgttctta 109920
cgtgaacctg ttaacgattt cgatttgtat tttaagaaca taaaagcagc tactatggta 109980
gcacgacact actgtattaa gtggtcacag gacaatgaag tacaacgaaa agctggacat 110040
gttgtaaagg atattgaacc tgtattacgt gtaacattct ctgatgaaga tagtgattac 110100
aaagcagtac gaaagttctt agataaactg gatacagatt taagccgtgt gcttaatggt 110160
acggatcacg agggaagaac acgagctatc attcatccta aagataaagc actagatgga 110220
ctattagaga gtggttggta tatcatgaaa cgtgtagaaa tcttcattca aagtcaaggg 110280
tttgtaggtg ataatccaga tgaagagtac gattactttg aaggtcgtga agtctctgca 110340
gcagaagatt tcattgataa aagtcttgca actaacgaag aagggttgaa tgagaagggt 110400
gaaaaatatc gaacagtatt tatgtcttcc aacgccatta cactttctga taagattcaa 110460
attgttattc gcttctttgg agaacctagt aagattcatg acacttatga ttttattcat 110520
gcaaccaact actggacgaa gaaagagggt ttagtaacaa atactcgtgc tttagaggcc 110580
cttcttgcca aagaacttgt atactccggt agccgctacc cattggcgag tatattcagg 110640
actcggaaat tcattaagcg tgagtggacc tgccatgttg gtaactttgt taaaatggca 110700
atgcaactta atgaaatgga tttaacacaa ccagatatcc ttgaagaaca attaactggt 110760
gtagatgcag cttacttgtt ccaaattatc aaagctgtta aagagaaacg taaggatgat 110820
ccagattttg aatttaattc tacttatatt tgcacactag tagatcgtat gatgggagaa 110880
tctggacaga ctgctgaaga tctagatatc gaccctgaaa ctatttaaaa taaaaccttg 110940
acacaaacta tcctctgaac tattatctta tcaaaaggta aaaacaagtt cagaggattt 111000
ttattatgtc acgtaatata gcttacttaa gaatatcaac ggcacacctt gaccagagca 111060
ccgaacgcca gctcaatgtt ggtataggtt ttgataaaac atttgaggat aaagcttctg 111120
gtaagagtat caacaatcgt ccagcattta tcgagatgct tgaatatgtg caagagaatg 111180
acactatcca tatccaatca aatgatcgct gcttccgtaa tgttaaagaa atgttaaatt 111240
ttatagagtg tatgcttgat cgtaagatta atattagatt acacacagag aatcttcatt 111300
ttatacatga tggtaatgag atgatgctcg cccaaaataa actaatgctc acaaacttag 111360
cagcgttctc tgaatttttc cttacacaga acagggttgc aattaagcaa ggtcttgctg 111420
tagctaagaa gaagggtaac cttaagaaga caaaggggac aaaatggcac gaaacctata 111480
ccgccaatcg cgctgcaggt aagcactcca caacaaagct gttcaaacct tctccacaaa 111540
aagataaatt aattgtggac atcaaaacag caatcagtta tggtagtcct aaatcttttg 111600
ttgaacttgc agataagctt aacaaaaatg aagtatttac tttagggagt aaaccttgga 111660
atggtaggtc attagcgacc ttctgtcaga gaaatgaaat taaattgtaa aggagataat 111720
tatgtactgg aaaattacag cttataatgg aactacatgg gaagccacta gaacaatgta 111780
tattgaagaa gctataacat catttattaa agatactggc ctgtgtcaat gggatatcaa 111840
atctatttta aaccagcact gataagaagg agaaataatc atgggagtat tggcatgtga 111900
ccgaaatggt tgcgataaca tcatgtgtga tttcacaagt tatgagcgtg gtgaatatct 111960
ttgttgggaa tgtaaacagg aattgatcgc caaagggttt tgtgatattg atgaattcat 112020
gggcagtaag aaacgtccag acaacagtag tgaagcttgg aaagaatatg tgaataaggt 112080
tttcaaaagt cgatatgagg agggagaata gtggatatta aattagaaga ttatctatcg 112140
gaagaagaaa ttaaagaatt acttggtcaa acaatacaag ctaaatgtga agcttatctt 112200
gagaataatt tcgaacgtat ggtgtctaat acagcctatt atgttgtgtg ggagagtgta 112260
gatgaagtta ttgatggaac attcaaacag caacttgaaa ataatgttca aaaggtcatg 112320
a 112321
Claims (10)
1. A Vibrio parahaemolyticus phage is characterized in that the phage is Vibrio parahaemolyticus phage (Vibrio parahaemolyticus phage) RDP-VP-21007, and the head of the Vibrio parahaemolyticus phage (Vibrio parahaemolyticus phage) RDP-VP-21007 is in a regular hexagon shape, the diameter of the head is about 55nm, the Vibrio parahaemolyticus phage has a tail part, and the preservation number is CGMCC No. 22492.
2. The Vibrio parahaemolyticus phage of claim 1, wherein the Vibrio parahaemolyticus phage (Vibrio parahaemolyticus phase) RDP-VP-21007 has a strong lytic effect on Vibrio parahaemolyticus in an aqueous body.
3. Use of the vibrio parahaemolyticus phage RDP-VP-21007 of any one of claims 1-2 in the preparation of a medicament for the prevention and or treatment of diseases caused by vibrio parahaemolyticus.
4. Use of the vibrio parahaemolyticus phage RDP-VP-21007 according to any one of claims 1-2 for the preparation of a feed for the prevention and or treatment of diseases caused by vibrio parahaemolyticus.
5. A bactericidal composition for controlling Vibrio parahaemolyticus comprising an effective amount of Vibrio parahaemolyticus phage (Vibrio parahaemolyticus phase) RDP-VP-21007 according to claim 1.
6. Use of a Vibrio parahaemolyticus phage according to any one of claims 1 to 2, wherein the Vibrio parahaemolyticus phage (Vibrio parahaemolyticus phase) RDP-VP-21007 is used to provide a potential therapeutic drug or health product for bacterial infection caused by Vibrio parahaemolyticus.
7. An additive for preventing and/or treating diseases caused by Vibrio parahaemolyticus, which comprises Vibrio parahaemolyticus phage (Vibrio parahaemolyticus phase) RDP-VP-21007 as an active ingredient.
8. A cleaning or disinfecting agent for an aquaculture environment comprising Vibrio parahaemolyticus phage (Vibrio parahaemolyticus phase) RDP-VP-21007 according to claim 1.
9. Use of a Vibrio parahaemolyticus phage according to any one of claims 1 to 2, wherein the Vibrio parahaemolyticus phage (Vibrio parahaemolyticus phase) RDP-VP-21007 is used as a biological bactericide.
10. Use of a Vibrio parahaemolyticus phage according to any one of claims 1 to 2, wherein the Vibrio parahaemolyticus phage (Vibrio parahaemolyticus phase) RDP-VP-21007 is a medical device for the treatment and prevention of bacterial infections caused by Vibrio parahaemolyticus.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116732006A (en) * | 2023-08-09 | 2023-09-12 | 山东省农业科学院畜牧兽医研究所 | Vibrio parahaemolyticus phage depolymerase and application thereof |
| CN116732006B (en) * | 2023-08-09 | 2023-11-17 | 山东省农业科学院畜牧兽医研究所 | Vibrio parahaemolyticus phage depolymerase and application thereof |
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Application publication date: 20211102 |