KR102193473B1 - Novel Klebsiella genus bacteria specific bacteriophage KP12 and antibacterial composition comprising the same - Google Patents

Novel Klebsiella genus bacteria specific bacteriophage KP12 and antibacterial composition comprising the same Download PDF

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KR102193473B1
KR102193473B1 KR1020180169895A KR20180169895A KR102193473B1 KR 102193473 B1 KR102193473 B1 KR 102193473B1 KR 1020180169895 A KR1020180169895 A KR 1020180169895A KR 20180169895 A KR20180169895 A KR 20180169895A KR 102193473 B1 KR102193473 B1 KR 102193473B1
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연영은
김현일
박철세
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Abstract

본 발명은 클렙시엘라(Klebsiella) 속 세균, 특히 ESBL(Extended-spectrum beta-lactamase)-클렙시엘라 속 세균에 특이적인 사멸능을 갖는 신규 박테리오파지 KP12, 상기 박테리오파지를 포함하는 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제 또는 세척제 및 상기 박테리오파지를 개체에 투여하는 단계를 포함하는 클렙시엘라에 의한 감염성 질병의 예방 또는 치료 방법에 관한 것이다. 본 발명의 박테리오파지 KP12를 이용한 클렙시엘라 속 세균에 의한 감염성 질병의 예방 또는 치료 방법은 기존의 항생제 등의 화학물질에 비해 클렙시엘라 속 세균, 특히 ESBL-클렙시엘라 속 세균에 대한 특이성이 매우 높고, 상기 박테리오파지 KP12는 클렙시엘라 속 세균에 감염하여 탁월한 용균 활성을 나타내고 물리화학적 자극에 강하다는 장점을 가지고 있다. 또한 본 발명의 박테리오파지 KP12는 사람, 동물, 식물 등 세균 외의 다른 숙주에는 감염되지 않으므로, 항생제의 오남용으로 인한 항생제 내성균의 문제점, 식품 내의 항생제의 잔류 문제, 광범위한 숙주범위의 문제점을 해결할 수 있는 장점이 있다. 따라서, 본 발명의 박테리오파지 KP12는 클렙시엘라 속 세균에 의한 감염성 질병의 예방 또는 치료, 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제, 또는 세척제 분야에서 다양하게 사용될 수 있다.The invention Ella (Klebsiella) in bacteria, especially ESBL (Extended-spectrum beta-lactamase ) when keulrep was added keulrep for new bacteriophage KP12, a composition for antibiotic containing the bacteriophage, animal feed having a specific apoptotic function in Ella bacteria belonging to the genus It relates to a method for preventing or treating infectious diseases caused by Klebsiella comprising the step of administering a composition, feed, disinfectant or cleaning agent, and the bacteriophage to an individual. The method of preventing or treating infectious diseases caused by bacteria of the genus Klebsiella using the bacteriophage KP12 of the present invention has very specificity for bacteria of genus Klebsiella, especially ESBL-Klebsiella, compared to chemical substances such as antibiotics. High, the bacteriophage KP12 has the advantage of being resistant to physicochemical stimulation and exhibits excellent lytic activity by infecting Klebsiella genus bacteria. In addition, since the bacteriophage KP12 of the present invention does not infect other hosts other than bacteria such as humans, animals, plants, etc., it has the advantage of solving the problems of antibiotic-resistant bacteria due to misuse of antibiotics, the problem of residual antibiotics in food, and problems of a wide host range. have. Therefore, the bacteriophage KP12 of the present invention can be used in various fields in the field of prevention or treatment of infectious diseases caused by bacteria of the genus Klebsiella, antibiotic compositions, feed addition compositions, feed, disinfectants, or cleaning agents.

Description

신규한 클렙시엘라 속 세균 특이 박테리오파지 KP12 및 이를 포함하는 항균 조성물{Novel Klebsiella genus bacteria specific bacteriophage KP12 and antibacterial composition comprising the same}Novel Klebsiella genus bacteria specific bacteriophage KP12 and antibacterial composition comprising the same}

본 발명은 클렙시엘라(Klebsiella) 속 세균, 특히 ESBL(Extended-spectrum beta-lactamase)-클렙시엘라 속 세균에 특이적인 사멸능을 갖는 신규 박테리오파지 KP12, 상기 박테리오파지를 포함하는 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제 또는 세척제 및 상기 박테리오파지를 개체에 투여하는 단계를 포함하는 클렙시엘라에 의한 감염성 질병의 예방 또는 치료 방법에 관한 것이다.The invention Ella (Klebsiella) in bacteria, especially ESBL (Extended-spectrum beta-lactamase ) when keulrep was added keulrep for new bacteriophage KP12, a composition for antibiotic containing the bacteriophage, animal feed having a specific apoptotic function in Ella bacteria belonging to the genus It relates to a method for preventing or treating infectious diseases caused by Klebsiella comprising the step of administering a composition, feed, disinfectant or cleaning agent, and the bacteriophage to an individual.

일반적으로 클렙시엘라(Klebsiella) 속 세균은 장내세균과의 한 속명으로, 그람음성 간균이다. 편모는 없고, 협막을 지나다니면서 점액을 생산하는 것이 특징이다. 구연산염으로부터 탄소원을 얻고, 여러 가지 탄수화물에서 황화수소를 제외한 산과 가스를 발생시킨다. 자연계에 널리 존재하며, 사람의 호흡기, 장관, 비뇨기에서 검출되며 급성 폐렴의 원인균으로 알려져 있다. 최근에는 다양한 클렙시엘라 속 세균이 진단, 검출되고 있는데, 폐렴간균(Klebsiella pneumoniae), 클렙시엘라 오자에나에(Klebsiella ozaenae), 클렙시엘라 리노스클레로마티스(Klebsiella rhinoscleromatis) 등이 존재한다.In general, Klebsiella ( Klebsiella ) genus bacteria is a genus name of the intestinal bacteria, Gram-negative bacillus. There is no flagella and is characterized by producing mucus while passing through the capsular membrane. It obtains a carbon source from citrate and produces acids and gases other than hydrogen sulfide from various carbohydrates. It is widely present in nature, is detected in human respiratory, intestinal, and urinary tract, and is known as the causative agent of acute pneumonia. Recently, various bacteria of the genus Klebsiella have been diagnosed and detected, and there are pneumococcal ( Klebsiella pneumoniae ), Klebsiella ozaenae ( Klebsiella ozaenae ), Klebsiella rhinoscleromatis , and the like.

임상적 측면에서 클렙시엘라 속 세균 중 대부분을 차지하는 것으로 알려진 폐렴간균(Klebsiella pneumoniae)은 그람음성(Gram negative)의 간균, 통성혐기성 또는 호기성 세균으로 사람의 장관 내, 피부, 구강, 호흡기 등에 상재하고 있으며. 폐렴의 10~20%는 이 균에 의한다고 한다. 또한 요로감염증에서 분리되는 경우도 있으며, 패혈증, 복강 내 감염 등의 주 원인균으로 보고되고 있으며, 중환자실 환자에서 발생하는 균혈증의 원인균으로 높은 감염률을 보이고 있다. Klebsiella pneumoniae , which is known to account for most of the bacteria of the genus Klebsiella in clinical terms, is a Gram-negative bacillus, anaerobe, or aerobic bacteria that is present in the human intestine, skin, oral cavity, and respiratory tract. And. It is said that 10-20% of pneumonia is caused by this fungus. In addition, it is sometimes isolated from urinary tract infections, and is reported as the main causative agent of sepsis and intraperitoneal infection, and it is the causative agent of bacteremia that occurs in intensive care unit patients, showing a high infection rate.

한편, 현재 발견되는 클렙시엘라 속 세균인 폐렴간균 중에서도 항생제 내성을 나타내는 세균인 ESBL(Extended-spectrum beta-lactamase)-폐렴간균이 35~45%에 이르는 것으로 밝혀져 임상에서의 ESBL-폐렴간균의 사멸의 중요성은 크다고 할 수 있다. 현재 미생물을 효과적으로 사멸시킬 수 있는 다양한 항균제가 사용되고 있는데, ß-lactam(베타락탐) 계열의 항생제는 현재 사용되고 있는 항균제의 약 50%이상을 차지하고 있다. 그러나 이러한 베타락탐 계열의 항생제에 대해 다양한 세균 특히 그람음성의 장내 세균들은 베타락탐 ring을 분해할 수 있는 효소인 ß-lactamase를 생성함으로써 이러한 계열의 항생제에 내성을 나타낼 수 있다. 이를 ESBL(Extended-spectrum ß-lactamase) 세균으로 분류할 수 있는데, 폐렴간균 뿐 아니라 대장균(Escherichia coli), 엔테로박터 속(Enterobacter spp.), 시트로박터 속(Citrobacter spp.), 세라티아 속(Serratia spp.), 프로비덴시아 속(Providencia spp.) 등 다양한 세균들이 ß-lactamase를 생성함으로써 베타락탐 계열의 항생제에 대해 내성을 나타내고 있다. ESBL이 최초로 보고된 곳이 유럽이며 현 시점에서도 ESBL은 유럽에서 많은 발생 빈도를 보이고 있는데, 특히 폐렴간균의 ESBL 생성균의 비중이 최대 35%까지 보고되고 있다. 미국의 경우 90년대 들어 20%에 육박하였고, 미국, 대한, 호주 등이 참여한 폐렴간균 균혈증에 관한 최근의 한 전형적 연구에서 ESBL 생성균주가 18.7% 이었다. On the other hand, among the currently discovered Klebsiella genus pneumococcus, ESBL (Extended-spectrum beta-lactamase)-pneumococcus, an antibiotic-resistant bacterium, was found to be 35-45%, killing ESBL-pneumococci in clinical practice. The importance of can be said to be great. Currently, various antimicrobial agents that can effectively kill microorganisms are used, and ß-lactam (betalactam) antibiotics account for more than 50% of currently used antimicrobial agents. However, against these beta-lactam antibiotics, various bacteria, especially Gram-negative intestinal bacteria, can be resistant to these antibiotics by generating ß-lactamase, an enzyme that can degrade the beta-lactam ring. This can be classified as ESBL (Extended-spectrum ß-lactamase) bacteria, as well as pneumococci, Escherichia coli, Enterobacter spp., Citrobacter spp., and Serratia spp. Serratia spp.), Providencia spp., and other bacteria are resistant to beta-lactam antibiotics by producing ß-lactamase. ESBL was first reported in Europe, and even at this point, ESBL is showing a high frequency in Europe. In particular, the proportion of ESBL-producing bacteria in pneumococcal bacteria is reported up to 35%. In the United States, it reached 20% in the 1990s, and in a recent typical study on pneumococcal bacteremia in which the United States, Korea, and Australia participated, the ESBL-producing strain was 18.7%.

우리나라에서도 마찬가지로 ESBL은 국내에서 분리되는 다수의 그람음성세균에서 발견되는데, 폐렴간균은 대장균과 함께 흔히 보고되고 있다. 최근에 국내에서 시행된 연구에 따르면 혈액에서 배양된 폐렴간균 중 ESBL 생성균주는 27.2-52.9%로 보고되었다. 80년대에는 1-6% 정도로 미미하던 ESBL균의 비율이 최근 5-10배 이상 증가하였다는 것은 ESBL 폐렴간균이 병원 감염에서 차지하는 비중이 더욱 커질 것으로 전망되며, 이들의 전파를 방지하기 위해서는 철저한 병원 감염 관리가 필요하며 항생제의 사용을 더욱 신중히 해야 할 것이다. 대부분의 폐렴간균은 다양한 항생제에 내성을 나타내고 있어 감염되면 질병을 치료하는데 있어 어려울 수 있다. 그러나 새로운 항생제를 개발하는 데에는 많은 비용과 시간이 소요되고 있어 항생제를 대체할 수 있는 물질의 요구가 큰 실정이다. In Korea, ESBL is also found in a number of Gram-negative bacteria isolated in Korea, and pneumococcal bacteria are commonly reported along with E. coli. According to a recent study conducted in Korea, ESBL-producing bacteria were reported to be 27.2-52.9% of pneumococcal bacteria cultured in blood. The fact that the proportion of ESBL bacteria, which was insignificant at 1-6% in the 1980s, has increased more than 5-10 times in recent years, is expected to increase the share of ESBL pneumonia bacillus in hospital infections. To prevent their spread, thorough hospitals Infection control is necessary and antibiotics should be used more carefully. Most pneumococcal bacteria are resistant to various antibiotics, so infection can be difficult to treat disease. However, it takes a lot of time and cost to develop a new antibiotic, so there is a great demand for a substance that can replace the antibiotic.

한편, 박테리오파지(bacteriophage)는 특정 세균을 감염시켜 감염된 세균의 성장을 억제하고 저해하는 세균 특이적 바이러스를 의미한다. 박테리오파지는 박테리아에 감염(infection)한 후 박테리아 세포 내부에서 증식을 하고, 증식 후 자손 박테리오파지들이 박테리아 밖으로 나올 때 숙주인 박테리아의 세포벽을 파괴하는 방식으로 박테리아를 사멸시키는 능력을 갖고 있다. 박테리오파지의 박테리아 감염 방식은 매우 특이성이 높아서 특정 박테리아에 감염할 수 있는 박테리오파지의 종류는 일부로 한정된다. 즉, 특정 박테리오파지는 특정 범주의 박테리아에만 감염할 수 있고 이로 인하여 특정 박테리오파지는 특정 박테리아만을 사멸시키며 다른 박테리아에는 영향을 주지 않는다. 따라서 최근 세균성 질환의 대처 방안으로 박테리오파지(bacteriophage)의 활용이 크게 주목을 받고 있다. 특히 2000년 이후에 항생제 내성균의 증가로 인하여 기존 항생제의 한계성이 나타나고, 기존 항생제의 대체 물질로의 개발 가능성이 부각되면서 다시 박테리오파지가 항-박테리아제로 주목을 받고 있다.On the other hand, bacteriophage refers to a bacteria-specific virus that inhibits and inhibits the growth of infected bacteria by infecting specific bacteria. Bacteriophages have the ability to kill bacteria by proliferating inside bacterial cells after infection with bacteria, and destroying the cell walls of host bacteria when progeny bacteriophages come out of the bacteria after proliferation. The bacterial infection method of bacteriophage is very specific, so the types of bacteriophage that can infect specific bacteria are limited to some. That is, a specific bacteriophage can infect only a specific category of bacteria, and because of this, a specific bacteriophage kills only specific bacteria and does not affect other bacteria. Therefore, the use of bacteriophage as a countermeasure for recent bacterial diseases is receiving great attention. In particular, after 2000, the limitations of existing antibiotics appeared due to the increase in antibiotic-resistant bacteria, and the possibility of development as a substitute for the existing antibiotics emerged. As a result, bacteriophage is again attracting attention as an anti-bacterial agent.

현재까지 클렙시엘라 속 세균, 특히 ESBL-클렙시엘라 속 세균에 의한 감염증을 예방 또는 치료하기 위한 신규한 박테리오파지에 대한 연구는 여전히 부족한 실정이다. 따라서 클렙시엘라 속 세균, 특히 ESBL-클렙시엘라 속 세균에 특이적인 용균활성을 갖는 박테리오파지 및 이의 응용에 대한 기술 개발이 필요하다.Until now, studies on novel bacteriophages for preventing or treating infections caused by bacteria of the genus Klebsiella, particularly ESBL-Klebsiella, are still insufficient. Therefore, there is a need to develop a technology for a bacteriophage having a specific lytic activity for bacteria of the genus Klebsiella, especially ESBL-Klebsiella, and its application.

이에 본 발명자들은 클렙시엘라 속 세균에 특이적인 용균활성을 갖는 박테리오파지를 분리하고 분리된 박테리오파지의 형태적 및 유전적 특성을 분석하여 상기 박테리오파지가 클렙시엘라 속 세균, 특히 폐렴간균을 선택적으로 사멸할 수 있고, 더 나아가 항생제에 내성을 가지는 ESBL-폐렴간균을 선택적으로 사멸시킬 수 있음을 확인함으로써 본 발명을 완성하였다.Accordingly, the present inventors isolated a bacteriophage having a specific lytic activity for bacteria of the genus Klebsiella and analyzed the morphological and genetic characteristics of the isolated bacteriophage, so that the bacteriophage could selectively kill bacteria of the genus Klebsiella, particularly pneumococcal bacteria. In addition, the present invention was completed by confirming that it can selectively kill ESBL-pneumococcal bacteria resistant to antibiotics.

본 발명의 목적은 클렙시엘라 속 세균에 특이적인 사멸능을 갖는, 서열번호 1로 표시되는 염기서열로 이루어진 박테리오파지 KP12를 제공하는 것이다.An object of the present invention is to provide a bacteriophage KP12 consisting of a nucleotide sequence represented by SEQ ID NO: 1, which has a specific killing ability for bacteria of the genus Klebsiella.

본 발명의 또 다른 목적은 상기 박테리오파지 KP12를 포함하는, 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제 또는 세척제를 제공하는 것이다.Another object of the present invention is to provide a composition for antibiotics, a composition for feed addition, feed, a disinfectant or a cleaning agent, including the bacteriophage KP12.

본 발명의 또 다른 목적은 상기 박테리오파지 KP12를 개체에 투여하는 단계를 포함하는, 클렙시엘라 속 세균에 의한 감염성 질병의 예방 또는 치료 방법을 제공하는 것이다.Another object of the present invention is to provide a method for preventing or treating infectious diseases caused by bacteria of the genus Klebsiella, comprising administering the bacteriophage KP12 to an individual.

상기 목적을 달성하기 위하여, 본 발명은 클렙시엘라 속 세균에 특이적인 사멸능을 갖는, 서열번호 1로 표시되는 염기서열로 이루어진 박테리오파지 KP12를 제공한다.In order to achieve the above object, the present invention provides a bacteriophage KP12 consisting of a nucleotide sequence represented by SEQ ID NO: 1, having a specific killing ability for bacteria of the genus Klebsiella.

또한, 본 발명은 상기 박테리오파지 KP12를 포함하는, 항생용 조성물을 제공한다.In addition, the present invention provides a composition for antibiotics, including the bacteriophage KP12.

또한, 본 발명은 상기 박테리오파지 KP12를 포함하는, 사료 첨가용 조성물을 제공한다.In addition, the present invention provides a composition for feed addition, including the bacteriophage KP12.

또한, 본 발명은 상기 사료 첨가용 조성물을 포함하는, 사료를 제공한다.In addition, the present invention provides a feed comprising the composition for feed addition.

또한, 본 발명은 상기 박테리오파지 KP12를 포함하는, 소독제를 제공한다.In addition, the present invention provides a disinfectant comprising the bacteriophage KP12.

또한, 본 발명은 상기 박테리오파지 KP12를 포함하는, 세척제를 제공한다.In addition, the present invention provides a cleaning agent comprising the bacteriophage KP12.

또한, 본 발명은 상기 박테리오파지 KP12를 개체에 투여하는 단계를 포함하는, 클렙시엘라 속 세균에 의한 감염성 질병의 예방 또는 치료 방법을 제공한다.In addition, the present invention provides a method for preventing or treating infectious diseases caused by bacteria of the genus Klebsiella, comprising the step of administering the bacteriophage KP12 to an individual.

본 발명의 박테리오파지 KP12를 이용한 클렙시엘라 속 세균에 의한 감염성 질병의 예방 또는 치료 방법은 기존의 항생제 등의 화학물질에 비해 클렙시엘라 속 세균, 특히 ESBL-클렙시엘라 속 세균에 대한 특이성이 매우 높고, 상기 박테리오파지 KP12는 클렙시엘라 속 세균에 감염하여 탁월한 용균 활성을 나타내고 물리화학적 자극에 강하다는 장점을 가지고 있다. 또한 본 발명의 박테리오파지 KP12는 사람, 동물, 식물 등 세균 외의 다른 숙주에는 감염되지 않으므로, 항생제의 오남용으로 인한 항생제 내성균의 문제점, 식품 내의 항생제의 잔류 문제, 광범위한 숙주범위의 문제점을 해결할 수 있는 장점이 있다. 따라서, 본 발명의 박테리오파지 KP12는 클렙시엘라 속 세균에 의한 감염성 질병의 예방 또는 치료, 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제, 또는 세척제 분야에서 다양하게 사용될 수 있다.The method of preventing or treating infectious diseases caused by bacteria of the genus Klebsiella using the bacteriophage KP12 of the present invention has very specificity for bacteria of genus Klebsiella, especially ESBL-Klebsiella, compared to chemical substances such as antibiotics. High, the bacteriophage KP12 has the advantage of being resistant to physicochemical stimulation and exhibits excellent lytic activity by infecting Klebsiella genus bacteria. In addition, since the bacteriophage KP12 of the present invention does not infect other hosts other than bacteria such as humans, animals, plants, etc., it has the advantage of solving the problems of antibiotic-resistant bacteria due to misuse of antibiotics, the problem of residual antibiotics in food, and problems of a wide host range. have. Therefore, the bacteriophage KP12 of the present invention can be used in various fields in the field of prevention or treatment of infectious diseases caused by bacteria of the genus Klebsiella, antibiotic compositions, feed addition compositions, feed, disinfectants, or cleaning agents.

도 1은 박테리오파지 KP12의 클렙시엘라 속 ESBL-폐렴간균에 대한 용균반 형성 활성을 확인한 결과를 나타낸 도이다.
도 3는 전자 현미경을 통해 박테리오파지 KP12의 형태학적 특성을 확인한 결과를 나타낸 도이다.
도 4은 박테리오파지 KP12의 단백질 패턴을 SDS-PAGE를 통해 확인한 결과를 나타낸 도이다.1 is a diagram showing the results of confirming the lysis plaque formation activity against ESBL-pneumoniae bacillus in Klebsiella genus of bacteriophage KP12.
3 is a diagram showing the results of confirming the morphological characteristics of bacteriophage KP12 through an electron microscope.
4 is a diagram showing the result of confirming the protein pattern of bacteriophage KP12 through SDS-PAGE.

이하, 본 발명에 대해 상세히 설명한다.Hereinafter, the present invention will be described in detail.

본 발명은 클렙시엘라(Klebsiella) 속 세균에 특이적인 사멸능을 갖는, 서열번호 1로 표시되는 염기서열로 이루어진 박테리오파지 KP12를 제공한다.The present invention provides a bacteriophage KP12 consisting of a nucleotide sequence represented by SEQ ID NO: 1, having a specific killing ability for bacteria of the genus Klebsiella .

본 발명에서, 용어 박테리오파지(bacteriophage)는 특정 세균에 감염하여 당해 세균의 성장을 억제하고 저해하는 세균 특이적 바이러스로, 단일 혹은 이중 사슬의 DNA 또는 RNA를 유전 물질로 포함하는 바이러스를 의미한다.In the present invention, the term bacteriophage is a bacterial-specific virus that inhibits and inhibits the growth of the bacterium by infecting a specific bacterium, and refers to a virus containing a single or double-stranded DNA or RNA as a genetic material.

본 발명의 박테리오파지 KP12는 클렙시엘라 속 세균, 특히 ESBL-페렴간균에 대해 용균활성이 탁월하다. 상기 박테리오파지 KP12는 200-210 nm의 크기로, 정이십면체의 머리를 가지며 수축성 꼬리가 있는 마이오비리대(Myoviridae)에 속한다. 본 발명의 박테리오파지 KP12는 단백질 패턴 분석 결과 74 kDa, 58 kDa, 43 kDa, 25 kDa, 24 kDa, 17 kDa, 12 kDa 그리고 11 kDa 크기의 단백질을 포함함을 확인하였다. 그 전체 염기서열을 서열번호 1로 표시하였다.The bacteriophage KP12 of the present invention has excellent lytic activity against bacteria of the genus Klebsiella, particularly ESBL-pneumoniae. The bacteriophage KP12 has a size of 200-210 nm, has a regular icosahedral head, and belongs to Myoviridae with a contractile tail. As a result of protein pattern analysis, the bacteriophage KP12 of the present invention was confirmed to contain proteins of size 74 kDa, 58 kDa, 43 kDa, 25 kDa, 24 kDa, 17 kDa, 12 kDa and 11 kDa. The entire nucleotide sequence is represented by SEQ ID NO: 1.

박테리오파지 KP12는 서열번호 1로 표시되는 염기서열을 전체 유전자의 전체 또는 일부로서 포함할 수 있다. 또한, 본 발명의 박테리오파지 KP12는 서열번호 1로 표시되는 염기서열, 및 상기 염기서열의 기능적 동등물로 이루어질 수 있다. 상기 기능적 동등물이란 염기서열의 변형, 치환의 결과, 상기 서열번호 1로 표시되는 염기서열과 적어도 70% 이상, 바람직하게는 80% 이상, 더욱 바람직하게는 90% 이상, 더더욱 바람직하게는 95% 이상의 서열 상동성을 갖는 것으로, 서열번호 1로 표시되는 염기서열과 실질적으로 동질의 생리활성을 나타내는 서열을 의미한다.Bacteriophage KP12 may include the nucleotide sequence represented by SEQ ID NO: 1 as all or part of the entire gene. In addition, the bacteriophage KP12 of the present invention may consist of a nucleotide sequence represented by SEQ ID NO: 1, and a functional equivalent of the nucleotide sequence. The functional equivalent is at least 70% or more, preferably 80% or more, more preferably 90% or more, even more preferably 95% of the base sequence represented by SEQ ID NO: 1 as a result of modification or substitution of the base sequence. It has the above sequence homology, and refers to a sequence that exhibits substantially the same physiological activity as the nucleotide sequence represented by SEQ ID NO: 1.

상기와 같은 클렙시엘라 속 세균 특이적 용균활성은 본 발명의 박테리오파지 KP12를 클렙시엘라 속 세균에 의한 감염성 질병의 예방 또는 치료용 조성물, 및 상기 박테리오파지 KP12를 유효 성분으로 포함하는 다양한 제품에 적용을 가능하게 한다.The bacteriophage specific lytic activity of the genus Klebsiella as described above is applied to a variety of products containing the bacteriophage KP12 of the present invention for the prevention or treatment of infectious diseases caused by bacteria of the genus Klebsiella, and the bacteriophage KP12 as an active ingredient. Make it possible.

본 발명의 박테리오파지 KP12는 상기 박테리오파지가 존재할 것으로 예상되는 하천으로부터 시료를 채취하여 분리한 박테리오파지로서, 본 발명자는 이를 박테리오파지 KP12로 명명하고 2017년 09월 13일에 한국미생물보존센터에 수탁번호 KFCC11737P로 기탁하였다. The bacteriophage KP12 of the present invention is a bacteriophage obtained by collecting and separating a sample from the river where the bacteriophage is expected to exist, and the present inventor named it bacteriophage KP12 and deposited with the Korean Microbiology Conservation Center as the accession number KFCC11737P on September 13, 2017. I did.

또한, 본 발명은 상기 박테리오파지 KP12를 포함하는, 항생용 조성물을 제공한다. In addition, the present invention provides a composition for antibiotics, including the bacteriophage KP12.

본 발명에서, 용어 항생용 조성물은 약제 형태로 동물에게 제공되어 균을 사멸시킬 수 있는 제제를 의미하며, 방부제, 살균제, 항생제 및 항균제를 총칭하는 것이다. In the present invention, the term antibiotic composition refers to a preparation that is provided to an animal in a pharmaceutical form to kill bacteria, and refers to preservatives, fungicides, antibiotics and antibacterial agents.

본 발명의 박테리오파지 KP12는 기존 항생제에 비하여 클렙시엘라 속 세균에 대한 특이성이 매우 높고, 동시에 베타락탐계 항생제 저항성 균에서도 작용하며, 유익균은 죽이지 않으면서 특정 병원균만 사멸시킬 수 있다. 아울러, 약물 내성 내지 저항성을 유도하지 않아, 기존의 항생물질에 비하여 제품수명(life cycling)이 긴 신규 항생제로서 이용될 수 있다는 이점이 있다.The bacteriophage KP12 of the present invention has very high specificity for bacteria of the genus Klebsiella compared to conventional antibiotics, and at the same time, it acts on beta-lactam antibiotic-resistant bacteria, and can kill only specific pathogens without killing beneficial bacteria. In addition, since it does not induce drug resistance or resistance, there is an advantage that it can be used as a novel antibiotic having a longer life cycle compared to existing antibiotics.

또한, 본 발명은 상기 박테리오파지 KP12를 포함하는, 사료 첨가용 조성물을 제공한다.In addition, the present invention provides a composition for feed addition, including the bacteriophage KP12.

축산, 수산업에서 사용되는 사료 첨가용 항생제는 질병의 예방 목적으로 사용되고 있는데, 예방 목적의 항생제 투여는 내성균 발생 가능성을 높이고 가축에 잔류하는 항생제가 사람에게 전달될 수 있어서 문제이다. 항생제가 육류를 통해 인체에 흡수되면 항생제 내성을 유발해 질병의 확산을 부를 수도 있다. 또한, 사료에 섞어 먹이는 항생제의 종류가 많고 이는 다제 내성균 발생 확률이 높아지는 문제점이 있기 때문에 좀 더 자연 친화적이면서도 기존의 항생제의 사용에서 발생한 문제를 해결할 새로운 사료 첨가용 항생물질로서 본 발명의 상기 박테리오파지 KP12를 이용할 수 있다.Feed-added antibiotics used in livestock and fishery industries are used for the purpose of preventing diseases, and administration of antibiotics for preventive purposes increases the likelihood of developing resistant bacteria and is a problem because antibiotics remaining in livestock can be delivered to humans. When antibiotics are absorbed into the body through meat, they can cause antibiotic resistance, which can lead to the spread of disease. In addition, since there are many types of antibiotics mixed with feed and this has a problem of increasing the probability of multidrug resistant bacteria, the bacteriophage KP12 of the present invention is a new feed additive that is more nature friendly and solves the problems arising from the use of existing antibiotics. You can use

또한, 본 발명은 상기 사료 첨가용 조성물을 포함하는 사료를 제공할 수 있으며, 본 발명의 사료는 박테리오파지를 사료 첨가제 형태로 따로 제조하여 사료에 혼합시키거나, 사료 제조 시 직접 첨가시켜 제조할 수 있다. 본 발명의 사료 내 박테리오파지는 액상 또는 건조상태일 수 있으며, 바람직하게는 건조된 분말형태이다. 건조방법은 통풍건조, 자연건조, 분무건조 및 동결건조가 가능하지만, 이에 제한되는 것은 아니다. 본 발명의 박테리오파지는 분말형태로 사료 중량의 0.05 내지 10 중량%, 바람직하게는 0.1 내지 2 중량%의 성분비로 혼합될 수 있다. 또한, 상기 사료는 본 발명의 박테리오파지 외에 사료의 보존성을 높일 수 있는 통상의 첨가제들을 추가로 포함할 수 있다.In addition, the present invention may provide a feed containing the composition for feed addition, and the feed of the present invention may be prepared by separately preparing bacteriophage in the form of a feed additive and mixing it with the feed, or by directly adding it when preparing the feed. . The bacteriophage in the feed of the present invention may be in a liquid or dry state, preferably in a dried powder form. The drying method may be ventilated drying, natural drying, spray drying, and freeze drying, but is not limited thereto. The bacteriophage of the present invention may be mixed in a powder form in a component ratio of 0.05 to 10% by weight, preferably 0.1 to 2% by weight of the feed weight. In addition, the feed may further include conventional additives that can increase the preservability of the feed in addition to the bacteriophage of the present invention.

본 발명의 사료 첨가용 조성물에는 비병원성의 다른 미생물이 추가로 첨가될 수 있다. 첨가될 수 있는 미생물로는 단백질 분해 효소, 지질 분해효소 및 당 전환 효소를 생산할 수 있는 바실러스 서브틸리스(Bacillus subtilis)와 같은 고초균, 소의 위와 같은 혐기적 조건에서 생리적 활성 및 유기물 분해능이 있는 락토바실러스 균주(Lactobacillus sp.), 가축의 체중을 증가시키며 우유의 산유량을 늘리고 사료의 소화 흡수율을 높이는 효과를 보여주는 아스퍼질러스 오리자에(Aspergillus oryzae)와 같은 사상균 및 사카로미세스 세레비지에(Saccharomyces cerevisiae)와 같은 효모로 구성된 군으로부터 선택될 수 있다.Other non-pathogenic microorganisms may be additionally added to the composition for feed addition of the present invention. Microorganisms that can be added include Bacillus subtilis , which can produce proteases, lipolytic enzymes, and sugar converting enzymes, and Lactobacillus, which has physiological activity and ability to degrade organic matter under anaerobic conditions such as the stomach of cattle. Strain ( Lactobacillus sp.), filamentous fungi such as Aspergillus oryzae and Saccharomyces cerevisiae showing the effect of increasing the weight of livestock, increasing milk production and increasing the digestion and absorption rate of feed. ) May be selected from the group consisting of yeast.

본 발명의 박테리오파지 KP12를 포함하는 사료에는 식물성으로는 곡물류, 근괴류, 식품가공 부산물류, 조류, 섬유질류, 제약 부산물류, 유지류, 전분류, 박류, 곡물부산물류 등이 있으며, 동물성으로는 단백질류, 무기물류, 유지류, 광물성류, 단세포 단백질, 동물성 플랑크톤류, 남은 음식물 등이 있으며 이에 제한되는 것은 아니다.The feed containing the bacteriophage KP12 of the present invention includes grains, muscle masses, food processing by-products, algae, fiber, pharmaceutical by-products, oils and fats, starches, meals, grain by-products, etc. as a vegetable, and protein as an animal. Types, inorganic logistics, oils, minerals, single-cell proteins, zooplanktons, food leftovers, etc., but are not limited thereto.

본 발명의 사료 첨가용 조성물에는 품질 저하를 방지하기 위하여 첨가하는 결착제, 유화제, 보존제 등이 포함될 수 있고, 효용 증대를 위하여 사료에 첨가하는 아미노산제, 비타민제, 효소제, 생균제, 향미제, 비단백태질소화합물, 규산염제, 완충제, 착색제, 추출제, 올리고당 등이 있으며, 그 외에도 사료 혼합제 등을 추가로 포함할 수 있다.The composition for feed addition of the present invention may contain binders, emulsifiers, preservatives, etc. added to prevent quality deterioration, and amino acids, vitamins, enzymes, probiotics, flavoring agents, non-proteinaceous agents added to the feed to increase utility Nitrogen compounds, silicates, buffers, colorants, extractants, oligosaccharides, etc. may be included. In addition, feed mixing agents may be additionally included.

또한, 본 발명은 박테리오파지 KP12를 포함하는, 음용수 첨가제를 제공한다.In addition, the present invention provides a drinking water additive, including bacteriophage KP12.

본 발명의 음용수 첨가제는 상기 박테리오파지 KP12 또는 이를 포함하는 조성물을 음용수 첨가제 형태로 따로 제조하여 사료 또는 음용수에 혼합하는 방식으로 사용되거나, 음용수 제조 시 직접 첨가하는 방식으로 사용할 수 있다. 상기와 같이 음용수에 혼합하여 공급함으로써 지속적으로 클렙시엘라 속 세균의 숫자를 감소시킬 수 있는 효과가 있다.The drinking water additive of the present invention may be used in a manner in which the bacteriophage KP12 or a composition containing the same is separately prepared in the form of a drinking water additive and used in a manner of mixing it with feed or drinking water, or it can be used in a manner that is directly added when preparing drinking water. By mixing and supplying it with drinking water as described above, there is an effect of continuously reducing the number of bacteria in the genus Klebsiella.

본 발명에서 음용수는 특별히 제한되지 아니하며, 당해 기술 분야에서 통상적으로 사용되는 음용수를 사용할 수 있다.In the present invention, drinking water is not particularly limited, and drinking water commonly used in the art may be used.

또한, 본 발명은 상기 박테리오파지 KP12를 포함하는, 소독제를 제공한다.In addition, the present invention provides a disinfectant comprising the bacteriophage KP12.

클렙시엘라 속 세균에 특이적 사멸능을 갖는 본 발명의 박테리오파지 KP12를 포함하는 소독제는 병원감염을 막기 위한 병원 및 보건용의 소독제로 유용하게 사용될 수 있고 일반 생활 소독제, 식품 및 조리 장소 및 설비의 소독제, 양계장, 축사 등의 건물, 축체, 음수, 깔짚, 난좌, 운반차량, 식기 등의 각종 생육 용품의 소독 등에 사용될 수 있다.The disinfectant comprising the bacteriophage KP12 of the present invention having a specific killing ability for bacteria in the genus Klebsiella can be usefully used as a disinfectant for hospitals and health care to prevent hospital infection, and as a disinfectant for general life, food and cooking places and facilities. It can be used for disinfection of various growth products such as disinfectants, poultry farms, buildings such as barns, livestock, drinking water, litter, nangja, transport vehicles, and tableware.

또한, 본 발명은 상기 박테리오파지 KP12를 포함하는, 세척제를 제공한다.In addition, the present invention provides a cleaning agent comprising the bacteriophage KP12.

본 발명의 박테리오파지 KP12는 클렙시엘라 속 세균에 특이적 사멸능을 가지므로, 클렙시엘라 속 세균에 노출되었거나 노출될 가능성이 있는 개체의 피부 표면 또는 신체 각 부위 등을 세척하는 용도로도 사용될 수 있다.Since the bacteriophage KP12 of the present invention has a specific killing ability against bacteria of the genus Klebsiella, it can also be used to clean the skin surface or parts of the body of individuals exposed to or likely to be exposed to bacteria of the genus Klebsiella. have.

또한, 본 발명은 상기 박테리오파지 KP12를 개체에 투여하는 단계를 포함하는, 클렙시엘라 속 세균에 의한 감염성 질병의 예방 또는 치료 방법을 제공한다.In addition, the present invention provides a method for preventing or treating infectious diseases caused by bacteria of the genus Klebsiella, comprising the step of administering the bacteriophage KP12 to an individual.

본 발명에서, 용어 "개체"는 클렙시엘라 속 세균에 의한 감염성 질병이 발병될 수 있는 모든 개체를 의미하는 것으로 인간을 포함한 포유동물, 가축류 또는 가금류를 포함하나, 이에 제한되는 것은 아니다. In the present invention, the term "individual" refers to any individual capable of developing infectious diseases caused by bacteria of the genus Klebsiella, and includes, but is not limited to, mammals, livestock, and poultry, including humans.

상기 용어 "가축류"는 인간에 의하여 순화, 개량되어 사람과 함께 공동생활을 하는 유용한 동물을 지칭하는 개념으로, 예를 들어, 돼지, 소, 닭, 말, 오리 또는 개 등을 포함하나, 이에 제한되는 것은 아니다.The term "livestock" is a concept that refers to a useful animal that has been purified and improved by humans to live in common with humans, and includes, for example, pigs, cows, chickens, horses, ducks or dogs, but is limited thereto. It does not become.

상기 용어 "가금류"는, 가축 중 조류에 속하는 동물을 총칭하여 이르는 개념으로, 예를 들어, 닭, 오리, 꿩, 메추리, 타조, 거위 또는 칠면조 등을 포함하나, 이에 제한되는 것은 아니다.The term "poultry" is a concept collectively referring to animals belonging to birds among livestock, and includes, for example, chickens, ducks, pheasants, quails, ostrichs, geese or turkeys, but is not limited thereto.

본 발명의 방법에서 상기 박테리오파지 KP12 또는 조성물은 약학적 제제의 형태로 동물에게 투여되거나, 가축의 사료 또는 음용수에 혼합하여 이를 섭식시키는 방법을 통해 투여될 수 있다.In the method of the present invention, the bacteriophage KP12 or composition may be administered to an animal in the form of a pharmaceutical formulation, or may be administered through a method of feeding it by mixing it with feed or drinking water of livestock.

본 발명의 방법에서 상기 박테리오파지 KP12 또는 조성물의 투여 경로는 목적 조직에 도달할 수 있는 한 경구 또는 비경구의 다양한 경로를 통하여 투여될 수 있으며, 구체적으로, 구강, 직장, 국소, 정맥 내, 복강 내, 근육 내, 동맥 내, 경피, 비측 내, 흡입 등을 통해 통상적인 방식으로 투여될 수 있다.In the method of the present invention, the route of administration of the bacteriophage KP12 or the composition may be administered through various routes, oral or parenteral, as long as it can reach the target tissue, and specifically, oral, rectal, topical, intravenous, intraperitoneal, It can be administered in a conventional manner via intramuscular, intraarterial, transdermal, intranasal, inhalation, and the like.

본 발명의 방법에 투여되는 상기 박테리오파지 KP12의 적합한 총 1일 사용량은 올바른 의학적 판단범위 내에서 처치의에 의해 결정될 수 있다는 것은 당업자에게 자명한 일이다. 특정 개체에 대한 구체적인 치료적 유효량은 달성하고자 하는 반응의 종류와 정도, 환자의 연령, 체중, 일반 건강 상태, 성별 및 식이, 투여시간, 투여 경로 및 조성물의 분비율, 치료기간, 구체적 조성물과 함께 사용되거나 동시 사용되는 약물을 비롯한 다양한 인자와 의약 분야에 잘 알려진 유사 인자에 따라 다르게 적용하는 것이 바람직하다.It is obvious to those skilled in the art that the appropriate total daily use amount of the bacteriophage KP12 administered in the method of the present invention can be determined by the treating physician within the correct medical judgment range. The specific therapeutically effective amount for a specific individual is determined along with the type and extent of the reaction to be achieved, the patient's age, weight, general health status, sex and diet, administration time, route of administration and secretion rate of the composition, treatment period, and specific composition. It is desirable to apply differently depending on various factors including drugs used or used simultaneously and similar factors well known in the medical field.

중복되는 내용은 본 명세서의 복잡성을 고려하여 생락하며, 본 명세서에서 달리 정의되지 않은 용어들은 본 발명이 속하는 기술분야에서 통상적으로 사용되는 의미를 갖는 것이다.Redundant content is omitted in consideration of the complexity of the present specification, and terms not otherwise defined herein have meanings commonly used in the technical field to which the present invention belongs.

이하, 본 발명을 실시예, 제제예에 의해 상세히 설명한다. 단, 하기 실시예, 제제예는 본 발명을 예시하는 것일 뿐 본 발명의 내용이 하기 실시예, 제제예에 한정되는 것은 아니다.Hereinafter, the present invention will be described in detail by examples and formulation examples. However, the following examples and formulation examples are merely illustrative of the present invention, and the contents of the present invention are not limited to the following examples and formulation examples.

실시예 1. 신규한 박테리오파지의 분리 및 배양Example 1. Isolation and culture of novel bacteriophage

1.1 박테리오파지의 스크리닝 및 분리1.1 Screening and isolation of bacteriophage

클렙시엘라 속 세균 중 폐렴간균(Klebsiella pneumoniae)에 특이적인 박테리오파지를 스크리닝 및 분리하기 위해서 용균반 분석을 수행하였다. 시료는 박테리오파지가 존재할 것으로 예상되는 대전 하수처리장으로부터 채취하였으며, 박테리오파지 분리에 사용된 폐렴간균은 아시아태평양 감염연구소에서 분양받은 것을 사용하였다.In order to screen and isolate a bacteriophage specific for Klebsiella pneumoniae among bacteria of the genus Klebsiella , lysis spot analysis was performed. Samples were collected from the Daejeon sewage treatment plant where bacteriophages are expected to exist, and the pneumococcal bacteria used to separate bacteriophages were purchased from the Asia Pacific Infection Research Institute.

구체적으로, 채취한 시료를 균질화 한 후 폐렴간균과 함께 35℃에서 하룻밤 동안 진탕배양 하였다. 상기 배양액을 4,000 rpm으로 20분간 원심분리한 후, 상등액을 공극(pore) 크기가 0.2 μm인 필터를 이용하여 여과하여 시료 여과액을 얻었다.Specifically, the collected sample was homogenized and cultured with pneumonia bacilli overnight at 35°C with shaking. After centrifuging the culture solution at 4,000 rpm for 20 minutes, the supernatant was filtered using a filter having a pore size of 0.2 μm to obtain a sample filtrate.

전배양된 클렙시엘라 속 세균 150 μL를 취해서 멸균된 튜브에 넣고 3 mL의 BHI 탑 아가(top agar) (뇌 심장 침출액(brain heart infusion) (뇌 침출 고체 12.5 g, 소 심장 침출액 고체 5.0 g, 프로테오스 펩톤 10.0 g, 글루코스 2.0 g, 염화나트륨 5.0 g, 인산나트륨 2.5 g/L) + 0.6 % 아가)를 첨가하여 잘 혼합한 후 미리 만들어 둔 2% BHI 아가 플레이트에 중층하였다. 실온에서 30분간 방치한 후 상기 시료 여과액을 각각 10 μL씩 점적하고, 다시 실온에서 30분간 방치한 후 35℃에서 24시간 동안 배양하여 박테리오파지의 유무를 확인하였다. Take 150 μL of pre-cultured Klebsiella bacteria and put them in a sterilized tube and put 3 mL of BHI top agar (brain heart infusion) (brain heart infusion 12.5 g, bovine heart leaching solid 5.0 g, Proteose peptone 10.0 g, glucose 2.0 g, sodium chloride 5.0 g, sodium phosphate 2.5 g/L) + 0.6% agar) were added, mixed well, and then layered on a 2% BHI agar plate made in advance. After allowing to stand at room temperature for 30 minutes, 10 μL of each of the sample filtrate was added dropwise, and then left at room temperature for 30 minutes and incubated at 35° C. for 24 hours to check the presence or absence of bacteriophage.

한편, 박테리오파지의 존재를 확인한 시료로부터 박테리오파지를 순수 분리하기 위해서 소프트 아가 오버레이(soft agar overlay)법을 이용하였다. 박테리오파지가 존재하는 것으로 확인된 시료를 식염수로 적절히 희석하여 각 희석단의 시료 희석액 100 μL를 취하고, 대상 세균(폐렴간균) 배양액 150 μL에 혼합한 후 0.6% BHI 탑 아가 3 mL을 첨가하여 잘 혼합한 뒤, 미리 만들어 둔 2% BHI 아가 플레이트에 중층하여 방치한 후 35℃에서 24시간 배양하였다. 배양한 각 플레이트에서 형성된 용균반을 확인한 후, 이를 선택하여 400 μL의 SM 완충액(NaCl 5.8 g/L; MgSO47H2O 2 g/L; 1M Tris-HCl(pH7.5) 50 mL)에 현탁하고, 실온에서 4시간 동안 방치하였다. 상기 박테리오파지 용액을 100 μL를 0.6% BHI 탑 아가와 세균배양액 500 μL와 혼합한 뒤 150 mm 지름의 BHI 플레이트에 분주하여 중층한 후 완전히 용균이 일어날 때까지 35℃에서 배양하였다. 배양이 종료된 후, BHI 플레이트에 15 mL의 SM 완충액을 가하고 실온에서 4시간 동안 천천히 교반하면서 박테리오파지 용액을 회수한 후 4,000 rpm으로 20분간 원심분리하여 상등액만 취하고 이를 0.2 μm 필터로 여과하여 최종 박테리오파지 용액을 회수하였다. 이렇게 얻어진 최종 박테리오파지의 용균반을 확인한 결과를 도 1에 나타내었다.On the other hand, in order to purely separate the bacteriophage from the sample confirming the presence of the bacteriophage was used a soft agar overlay (soft agar overlay) method. Dilute the sample confirmed to have bacteriophage properly with saline, take 100 μL of sample dilution from each dilution stage, mix it with 150 μL of the target bacteria (pneumococcal) culture solution, and add 3 mL of 0.6% BHI top agar to mix well. After that, it was layered on a 2% BHI agar plate made in advance, left to stand, and incubated at 35°C for 24 hours. After confirming the lysing plaques formed in each cultured plate, select it and add 400 μL of SM buffer (NaCl 5.8 g/L; MgSO 4 7H 2 O 2 g/L; 1M Tris-HCl (pH7.5) 50 mL). It was suspended and left at room temperature for 4 hours. 100 μL of the bacteriophage solution was mixed with 500 μL of 0.6% BHI top agar and bacterial culture solution, then dispensed on a 150 mm diameter BHI plate, layered, and incubated at 35° C. until complete lysis occurred. After the culture was completed, 15 mL of SM buffer was added to the BHI plate, and the bacteriophage solution was collected while slowly stirring at room temperature for 4 hours, and then centrifuged at 4,000 rpm for 20 minutes to take only the supernatant, which was filtered through a 0.2 μm filter to final bacteriophage. The solution was recovered. The results of confirming the lysis plate of the final bacteriophage thus obtained are shown in FIG. 1.

도 1에 나타낸 바와 같이, 1-2 mm의 크기를 가지는 용균반을 형성하는 박테리오파지를 확인하였고, 상기 박테리오파지는 클렙시엘라 속 세균의 대표 세균인 폐렴간균에 특이적인 용균능을 갖는 박테리오파지임을 확인하였다.As shown in Fig. 1, it was confirmed that the bacteriophage forming a lysis plate having a size of 1-2 mm was confirmed, and the bacteriophage was a bacteriophage having a specific lysis ability for pneumococcal, a representative bacterium of Klebsiella genus bacteria. .

1.2 박테리오파지의 대량 배양 및 정제1.2 Mass culture and purification of bacteriophage

상기 실시예　1.1에서 확인한 폐렴간균 특이적 박테리오파지를 대량 배양하기 위하여, 1.1에서 회수한 최종 박테리오파지 배양액을 1.0x108 PFU/mL로 희석한 후 전배양된 폐렴간균 1.0x109 CFU/mL과 혼합하여 MOI(Multiplicity of infection)가 0.1이 되도록 하여 35℃에서 100 rpm으로 18시간 동안 배양하였다. 배양이 종료된 후 배양액 전량을 6,000 rpm으로 30분간 원심분리하여 상등액을 수득하였고, 이를 0.2 μm 필터로 여과하여 최종 박테리오파지 배양액을 회수하였다. 분리된 박테리오파지를 박테리오파지 KP12(Bacteriophage KP12)로 명명하고, 2017년 09월 13일 한국미생물보존센터 (Korean Culture Center of Microorganisms, 서울, 한국)에 기탁하고 수탁번호 KFCC11737P를 부여받았다.In order to mass-cultivate the pneumococcal-specific bacteriophage identified in Example 1.1, the final bacteriophage culture medium recovered in 1.1 was 1.0x10 8 After diluting with PFU/mL, the mixture was mixed with 1.0x10 9 CFU/mL of pre-cultured pneumococcal bacteria to achieve a multiplicity of infection (MOI) of 0.1, followed by incubation at 35°C at 100 rpm for 18 hours. After the cultivation was completed, the total amount of the culture solution was centrifuged at 6,000 rpm for 30 minutes to obtain a supernatant, which was filtered through a 0.2 μm filter to recover the final bacteriophage culture solution. The isolated bacteriophage was named Bacteriophage KP12, and on September 13, 2017, it was deposited with the Korean Culture Center of Microorganisms (Seoul, Korea) and received the accession number KFCC11737P.

실시예 2. 박테리오파지 KP12의 전체 유전자 분석Example 2. Overall gene analysis of bacteriophage KP12

박테리오파지 KP12의 전체 유전자를 분석하기 위해, 박테리오파지 KP12 배양액에 20 mM EDTA, 50 μg/mL의 프로테나아제 K, 0.5%(w/v) SDS를 가한 후, 50℃에서 1시간 동안 정치하였다. 동량의 페놀-클로로포름-이소프로필 알코올(25:24:1)과 혼합한 후 실온에서 12,000 rpm으로 10분간 원심분리하여 상등액을 회수하였다. 회수된 상등액을 동일 부피의 페놀-클로로포름-이소프로필 알코올(25:24:1)과 혼합하여 실온에서 12,000 rpm으로 10분간 원심분리한 후 상등액을 회수하고, 상기 상등액에 3M 소듐 아세테이트를 전체 부피의 10%(v/v)가 되도록 가한 후 혼합하였다. 여기에 2배 부피의 차가운 95% 에탄올을 가하여 혼합한 뒤 -20℃에서 1시간 동안 정치하였다. 반응이 끝난 후 0℃에서 10분간 12,000 rpm으로 원심분리하여 침전물을 획득하였고, 차가운 70% 에탄올로 2회 세척한 뒤 에탄올을 완전히 제거하여 DNA 펠렛을 회수하였다. 회수한 펠렛을 최종 부피가 50 μL가 되도록 TE 완충액(Tris-EDTA, pH8.0)에 용해시킨 후 DNA 농도를 측정하였다. 전체 유전자 분석을 위해 마크로젠사의 PacBio RSII 를 이용하여 유전자 시퀀싱을 시행한 결과를 서열번호 1에 나타내었다.In order to analyze the entire gene of bacteriophage KP12, 20 mM EDTA, 50 μg/mL proteinase K, 0.5% (w/v) SDS were added to the bacteriophage KP12 culture medium, and then left at 50° C. for 1 hour. After mixing with the same amount of phenol-chloroform-isopropyl alcohol (25:24:1), the supernatant was recovered by centrifuging for 10 minutes at 12,000 rpm at room temperature. The recovered supernatant was mixed with an equal volume of phenol-chloroform-isopropyl alcohol (25:24:1), centrifuged at 12,000 rpm for 10 minutes at room temperature, and then the supernatant was recovered, and 3M sodium acetate was added to the supernatant. It was added to 10% (v/v) and then mixed. Two times the volume of cold 95% ethanol was added thereto, mixed, and left to stand at -20°C for 1 hour. After the reaction was completed, a precipitate was obtained by centrifugation at 0° C. for 10 minutes at 12,000 rpm. After washing twice with cold 70% ethanol, the ethanol was completely removed to recover the DNA pellet. The recovered pellet was dissolved in TE buffer (Tris-EDTA, pH 8.0) so that the final volume was 50 μL, and the DNA concentration was measured. For the whole gene analysis, the results of gene sequencing using Macrogen's PacBio RSII are shown in SEQ ID NO: 1.

시퀀싱 결과로 얻은 박테리오파지 KP12의 전체 유전자의 크기는 145,923 bp이며, GC함량이 45%, 전체 유전자의 수는 246개임을 확인하였다.It was confirmed that the size of the total genes of the bacteriophage KP12 obtained as a sequencing result was 145,923 bp, the GC content was 45%, and the total number of genes was 246.

실시예 3. 박테리오파지 KP12의 형태학적 특성Example 3. Morphological properties of bacteriophage KP12

박테리오파지 KP12의 형태학적 특성을 알아보기 위해, 배양액을 0.01% 젤라틴 용액에 희석하여 2.5% 글루타르알데하이드(glutaraldehyde) 용액으로 고정하였다. 이를 Carbon-coated mica plate(ca. 2.5 x 2.5 mm)에 적가한 후, 10분간 적응시켜 멸균증류수로 세척하였다. 이를 구리 격자(copper grid)에 끼워 2% 우라닐 아세테이트(Uranyl acetate)에서 30-60초간 염색하고 건조시킨 후, 투과전자현미경(Tecnai G2 Spirit Twin, Bio-Transmission electron microscope, 120 kV, 120,000~400,000)으로 관찰하였다. 그 결과를 도 3에 나타내었다.In order to investigate the morphological characteristics of the bacteriophage KP12, the culture medium was diluted in 0.01% gelatin solution and fixed with 2.5% glutaraldehyde solution. This was added dropwise to a carbon-coated mica plate (ca. 2.5 x 2.5 mm), acclimated for 10 minutes, and washed with sterile distilled water. It is inserted into a copper grid, dyed in 2% uranyl acetate for 30-60 seconds, dried, and then dried, followed by a transmission electron microscope (Tecnai G2 Spirit Twin, Bio-Transmission electron microscope, 120 kV, 120,000~400,000). ) Was observed. The results are shown in FIG. 3.

도 3에 나타낸 바와 같이, 박테리오파지 KP12는 200-210 nm의 크기로, 정이십면체의 머리를 가지며 수축성의 꼬리를 가지는 형태인 마이오비리대(Myoviridae)에 속함을 확인하였다.As shown in Figure 3, it was confirmed that the bacteriophage KP12 has a size of 200-210 nm, belongs to Myoviridae, which has a head of icosahedron and a contractile tail.

실시예 4. 박테리오파지 KP12의 단백질 패턴 분석Example 4. Analysis of protein pattern of bacteriophage KP12

박테리오파지 KP12의 단백질 패턴을 분석하기 위해, 1.0x1010 PFU/mL로 준비된 박테리오파지 KP12 40 μL를 10 μL의 5X 로딩 완충액과 혼합하고, 10분간 끓인 다음 12.5% SDS-PAGE를 수행하였다. SDS-PAGE 수행 후 단백질 전기영동 결과를 도 4에 나타내었다.To analyze the protein pattern of bacteriophage KP12, 40 μL of bacteriophage KP12 prepared at 1.0× 10 10 PFU/mL was mixed with 10 μL of 5× loading buffer, boiled for 10 minutes, and then 12.5% SDS-PAGE was performed. The results of protein electrophoresis after performing SDS-PAGE are shown in FIG. 4.

도 4에 나타낸 바와 같이, 박테리오파지 KP12는 74 kDa, 58 kDa, 43 kDa, 25 kDa, 24 kDa, 17 kDa, 12 kDa 그리고 11 kDa 크기의 주요 단백질을 가지는 것을 확인하였다.As shown in Figure 4, it was confirmed that the bacteriophage KP12 has major proteins of 74 kDa, 58 kDa, 43 kDa, 25 kDa, 24 kDa, 17 kDa, 12 kDa and 11 kDa.

실시예 5. 박테리오파지 KP12의 다양한 세균에 대한 감염성 조사Example 5. Infectivity investigation of bacteriophage KP12 against various bacteria

박테리오파지 KP12의 다양한 세균에 대한 감염성을 조사하였다. Infectivity of bacteriophage KP12 against various bacteria was investigated.

우선, 박테리오파지 KP12의 클렙시엘라 속 세균인 폐렴간균에 대한 용균 활성을 확인하기 위하여, 소프트 아가 오버레이법을 이용하여 아시아태평양 감염연구소에서 분양받은 ESBL(extended-spectrum beta-lactamase)-폐렴간균을 대상으로 용균 활성을 확인하였다. 그 결과를 표 1에 나타내었다.First, in order to confirm the lytic activity of bacteriophage KP12 against pneumococcus, a bacterium of the genus Klebsiella, a soft agar overlay method was used to target ESBL (extended-spectrum beta-lactamase)-pneumococcus that were sold in the Asia Pacific Infection Research Institute. The lysis activity was confirmed by. The results are shown in Table 1.

[표 1][Table 1]

Figure 112018130650592-pat00001
Figure 112018130650592-pat00001

(+; 용균활성 있음, -; 용균활성 없음)(+; lytic activity, -; lytic activity)

상기 표 1에 나타낸 바와 같이, 본 발명의 박테리오파지 KP12가 ESBL-폐렴간균에 대해서 용균활성을 나타냄을 통해 본 발명의 박테리오파지 KP12가 ESBL-폐렴간균, 즉 클렙시엘라 속 세균 중에서도 베타락탐계 항생제 내성 세균인 ESBL-클렙시엘라 속 세균에 대하여 탁월한 용균활성을 가짐을 확인하였다.As shown in Table 1, the bacteriophage KP12 of the present invention exhibits lytic activity against ESBL-pneumococcus, so that the bacteriophage KP12 of the present invention is ESBL-pneumococcal, that is, beta-lactam antibiotic-resistant bacteria among bacteria of the genus Klebsiella. It was confirmed that it has excellent lytic activity against bacteria of the genus ESBL-Klebsiella.

또한, 박테리오파지 KP12가 다른 속 세균에 대해서도 용균활성을 나타내는지 확인하기 위하여 ㈜옵티팜에서 분리하여 보유하고 있는 균주와 미생물 자원센터 등에서 분양받은 균주를 대상으로 소프트 아가 오버레이법을 통해서 감염성을 확인하였다. 그 결과를 표 2에 나타내었다.In addition, in order to confirm whether bacteriophage KP12 also exhibits lytic activity against other genus bacteria, infectivity was confirmed through the soft agar overlay method for the strains isolated and possessed by Optipharm Co., Ltd. and the strains sold in the microbial resource center. The results are shown in Table 2.

[표 2][Table 2]

Figure 112018130650592-pat00002
Figure 112018130650592-pat00002

(+: 용균활성 있음, -; 용균활성 없음)(+: has lytic activity, -; no lytic activity)

표 2에 나타낸 바와 같이, 본 발명의 박테리오파지 KP12는 클렙시엘라 속 세균인 폐렴간균 외 다른 속인 Salmonella 종이나 Escherichia coli, Bacillus 종, Lactobacillus plantarum 등의 균주에 대해서는 용균활성이 없는 것을 확인하였다.As shown in Table 2, it was confirmed that the bacteriophage KP12 of the present invention has no lytic activity for strains such as Salmonella species, Escherichia coli , Bacillus species, Lactobacillus plantarum, etc.

따라서, 본 발명의 박테리오파지 KP12는 클렙시엘라 속 세균에 특이적으로 용균활성을 나타내는 박테리오파지임을 확인하였다.Therefore, it was confirmed that the bacteriophage KP12 of the present invention is a bacteriophage that specifically exhibits lytic activity on bacteria of the genus Klebsiella.

실시예 6. 박테리오파지 KP12의 세균 사멸 능력Example 6. Bacteriophage KP12 ability to kill bacteria

박테리오파지 KP12의 클렙시엘라 속 세균인 ESBL 폐렴간균에 대한 세균 사멸 능력을 확인하기 위하여, 1시간 단위로 흡광도 600 nm에서 세균의 배양 상태를 관찰하였다. 600 nm에서 흡광도가 0.5 정도 되는 ESBL 폐렴간균 배양액을 10 mL 준비한 후, 세균 배양액에 농도가 1.0x109 PFU/mL 되는 박테리오파지액을 1 mL 넣은 군을 실험군으로 준비하였고, 실험군과 동일한 농도의 세균 배양액만 든 시료를 대조군으로 준비하였다. 이후 2시간 동안 배양하면서 1시간 단위로 흡광도 600 nm에서 세균의 배양 상태를 관찰하였고, 그 결과를 표 3에 나타내었다.In order to confirm the bacterial killing ability of the bacteriophage KP12 against ESBL pneumococcus, a bacterium of the genus Klebsiella, the culture state of the bacteria was observed at an absorbance of 600 nm every hour. After preparing 10 mL of ESBL pneumococcal culture solution having an absorbance of about 0.5 at 600 nm, a group containing 1 mL of a bacteriophage solution having a concentration of 1.0x10 9 PFU/mL was prepared as an experimental group, and a bacterial culture solution having the same concentration as that of the experimental group The prepared sample was prepared as a control. After incubation for 2 hours, the culture state of the bacteria was observed at an absorbance of 600 nm every 1 hour, and the results are shown in Table 3.

[표 3][Table 3]

Figure 112018130650592-pat00003
Figure 112018130650592-pat00003

표 3에 나타난 바와 같이, 박테리오파지 KP12를 첨가하지 않은 대조군의 경우 2시간 후 600 nm에서 흡광도가 3.03으로 나타나 ESBL 폐렴간균이 지속적으로 잘 성장한 것을 확인하였다. 반면, 박테리오파지 KP12를 첨가한 실험군의 경우 2시간 경과했을 때 600 nm에서 흡광도가 각각 0.54로 배양 초기와 비슷한 수치를 나타내는 것을 확인하였다. 따라서, 상기와 같은 결과로 박테리오파지 KP12가 클렙시엘라 속 세균인 ESBL 폐렴간균에 대하여 증식 억제능 뿐 아니라 짧은 시간 안에도 우수한 세균 사멸능을 나타내는 박테리오파지임을 확인하였다.As shown in Table 3, in the case of the control group to which the bacteriophage KP12 was not added, the absorbance at 600 nm was 3.03 after 2 hours, confirming that ESBL pneumococci continued to grow well. On the other hand, in the case of the experimental group to which the bacteriophage KP12 was added, it was confirmed that the absorbance at 600 nm was 0.54, respectively, after 2 hours, showing a value similar to that of the initial culture. Therefore, as a result of the above, it was confirmed that the bacteriophage KP12 is a bacteriophage that exhibits excellent bacterial killing ability within a short time as well as proliferation inhibition against ESBL pneumococcus, a bacterium of the genus Klebsiella.

상기 실험으로부터 박테리오파지 KP12는 클렙시엘라 속 세균, 특히 ESBL 폐렴간균에 대한 특이성이 매우 높고, ESBL 폐렴간균 내에서 증식함으로써 용균 활성이 우수하고 ESBL 폐렴간균 사멸능이 우수하다는 장점을 가지고 있음을 확인하였다. 또한 본 발명의 박테리오파지 KP12는 사람, 동물, 식물 등 세균 외의 다른 숙주에는 감염되지 않으므로, 항생제의 오남용으로 인한 항생제 내성균의 문제점, 식품 내의 항생제의 잔류 문제, 광범위한 숙주범위의 문제점을 해결할 수 있는 장점이 있다. 따라서, 본 발명의 박테리오파지 KP12는 ESBL 폐렴간균에 의한 감염성 질병의 예방 또는 치료방법, 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제, 또는 세척제 분야에서 다양하게 사용될 수 있다.From the above experiment, it was confirmed that the bacteriophage KP12 has very high specificity for bacteria of the genus Klebsiella, particularly ESBL pneumococcus, and has the advantage of excellent lytic activity and excellent ESBL pneumococcal killing ability by proliferating in ESBL pneumococcus. In addition, since the bacteriophage KP12 of the present invention does not infect other hosts other than bacteria such as humans, animals, plants, etc., it has the advantage of solving the problems of antibiotic-resistant bacteria due to misuse of antibiotics, the problem of residual antibiotics in food, and problems of a wide host range. have. Therefore, the bacteriophage KP12 of the present invention can be used in various ways in the field of preventing or treating infectious diseases caused by ESBL pneumococcal, antibiotic compositions, feed addition compositions, feed, disinfectants, or cleaning agents.

비록 본 발명이 상기에 언급된 바람직한 실시예로서 설명되었으나, 발명의 요지와 범위로부터 벗어남이 없이 다양한 수정이나 변형을 하는 것이 가능하다. 또한 첨부된 청구 범위는 본 발명의 요지에 속하는 이러한 수정이나 변형을 포함한다.Although the present invention has been described as the above-mentioned preferred embodiment, it is possible to make various modifications or variations without departing from the gist and scope of the invention. In addition, the appended claims include such modifications or variations that fall within the gist of the present invention.

이하, 제제예를 통하여 본 발명을 더욱 상세히 설명하고자 한다. 제제예는 오로지 본 발명을 예시하기 위한 것으로서, 본 발명의 범위가 제제예에 의해 제한되는 것으로 해석되지 않는다.Hereinafter, the present invention will be described in more detail through formulation examples. Formulation examples are for illustrative purposes only, and the scope of the present invention is not construed as being limited by formulation examples.

제제예 1. 사료 첨가용 조성물Formulation Example 1. Composition for feed addition

박테리오파지 KP12 1x109 PFU/mLBacteriophage KP12 1x10 9 PFU/mL

비타민 믹스 100 mg100 mg of vitamin mix

미네랄 믹스 100 mg100 mg of mineral mix

스테아린산 마그네슘 2 mg2 mg of magnesium stearate

통상의 사료 첨가제 제조방법에 따라 상기의 성분들을 혼합하여 제조한다.It is prepared by mixing the above ingredients according to a conventional feed additive manufacturing method.

제제예 2. 소독제 조성물Formulation Example 2. Disinfectant Composition

박테리오파지 KP12 1x109 PFU/mLBacteriophage KP12 1x10 9 PFU/mL

에탄올 적량Appropriate amount of ethanol

멸균 증류수 적량Proper amount of sterile distilled water

pH 조절제 적량proper amount of pH adjuster

통상의 소독제 제조방법에 따라 상기의 성분들을 혼합하여 제조한다.It is prepared by mixing the above components according to a conventional disinfectant manufacturing method.

제제예 3. 세척제 조성물Formulation Example 3. Cleaning agent composition

박테리오파지 KP12 1x109 PFU/mLBacteriophage KP12 1x10 9 PFU/mL

에탄올 적량Appropriate amount of ethanol

효소 복합물 적량Appropriate amount of enzyme complex

멸균 증류수 적량Proper amount of sterile distilled water

통상의 세척제 제조방법에 따라 상기의 성분들을 혼합하여 제조한다.It is prepared by mixing the above components according to a conventional cleaning agent manufacturing method.

이상, 본 발명내용의 특정한 부분을 상세히 기술하였는바, 당업계의 통상의 지식을 가진 자에게 있어서, 이러한 구체적인 기술은 단지 바람직한 실시양태일 뿐이며, 이에 의해 본 발명의 범위가 제한되는 것이 아닌 점은 명백할 것이다. 따라서 본 발명의 실질적인 범위는 첨부된 청구항들과 그것들의 등가물에 의해 정의된다고 할 것이다.Above, a specific part of the present invention has been described in detail, and for those of ordinary skill in the art, it is obvious that this specific technique is only a preferred embodiment, and the scope of the present invention is not limited thereby. something to do. Therefore, it will be said that the practical scope of the present invention is defined by the appended claims and their equivalents.

한국미생물보존센터(국내)Korea Microorganism Conservation Center (domestic) KFCC11737PKFCC11737P 2017091320170913

SEQUENCE LISTING <110> Optipharm.CO.,LTD <120> Novel Klebsiella genus bacteria specific bacteriophage KP12 and antibacterial composition comprising the same <130> optipharm1-64P <150> KR10-2017-0180949 <151> 2017-12-27 <160> 1 <170> PatentIn version 3.2 <210> 1 <211> 145923 <212> DNA <213> Artificial <220> <223> bacteriophage KP12 <400> 1 gacggacagc tccgggcgtc aaatatcttt acggatcttt acaaaatatc atgggcaagg 60 tcgatccggt ccccggtccc tcggggcctc ttcaggcgtg atagttactt gccgaaacta 120 ataataatca aatgtgacag atagcaagca tatggtttgc cagcttagag cacgatttgt 180 cattgacaag cttatattta tatgaattac accatttaac ataaaacacg ttatacgcac 240 tgaccaacaa cacatagcaa gctaataatg ccccaatgtt accagtgtga cgcacaggcc 300 agccacttca ggtcattaca tggtgtgact gttactgtgg tgatagttta atgtgtgatt 360 attcatgttt tagggttgtt ttgtgaatgg gacgacgaat gagaatcatt attatttcga 420 tttcgaattc aatttcgaaa tgagaatcat tccgcaaata taaatatttt gtaaatttat 480 aaataaaagc ttgacaagga gagagaattg tgtttaacac acagctctac tttgagcatt 540 tccgcaatga taatcattcc catcaacccc gttacggacc ggatacccgg caatgctaaa 600 gcattgaaat agttacaata agtaactatt ttctttattg ctacgcaagg gattgatagc 660 tatcccctat gataaattta tattgacact tcaggcaaac tatgctcaaa aacaacatgt 720 tttcattatc aataattctg gtttgtcaac cattattcac gatttaatgc gatttgatcg 780 catatagtaa ccatgtgtta tcatcacatc gccgcttcgc ggtgaagcgt ttagcttcat 840 agcttcgcta cgtaatcaca taccgacaca ataacacgag ggcgatcatg cgatagcgtg 900 atcggtgtta tcgtggcgat gtgataaaat taggctgtta atgattacgg atgtaatcat 960 ctaaatgtta atatttctaa ttcgctttta ggcgtctacg agccacgata acgcgaacga 1020 gaatgcgatt tgttcgcatt tgagttaccc tcgtgttatt gtgtcgctcg ctacgctcgc 1080 gccactcccc acgattacgc gaacgatttt tatttgacaa gattttattt ttatgctcaa 1140 taaaaccagt tcacacaata ggttagatga taaaagttat catttgagag tgattctcac 1200 actatgcata cataatgctt aaaaatgcat gttttattca gttaataaca tgcgttatta 1260 attgttgggg ttgttaggta gggccatacc attttaagcg caatatgcgc cattctgagg 1320 ggctttatct cttaccctgg ttagtgggtt accgcctgga gatctcgatt atgcaggttt 1380 tagtcaccta taactttttg attattgatt gataaaatct aacatataaa aacacaaaag 1440 ccgggagttg cccggcatta tttttgggga gtagtggagc cttacagcgc gatagccagc 1500 aggccagcga tcaagaaagg gagatcataa cggtctaaac gattaaagcg attaagttta 1560 atcagagtgt aaaacgtcaa ttgtaaaacg tcgatcatgg tgttaaaacc ttgcgccatt 1620 gtctcagtcg ttaccaggca agccagccag ttaaaacacg tattagacac taaagcaata 1680 aggcaagcca gcagggtagc gcgtaaaaga cttgttttgc ttacaatgta aatcatgttt 1740 gtcatttggt gttactcgtt taatgaggga ggtaaaagaa taacacacga aaaagggcgc 1800 tgcaatagcg ccccgatgtt taagctaatt caatctcaaa taaaacgccc atatagcgat 1860 catcacctga aagcgtagta acaattttca tacattcttc aaaggtccaa gccattgtag 1920 acccctggcg aacataagac acataaccgg tttttgaagt gcttttgata ttgtagcgga 1980 tatttgacat tttatttacc ttcggttttg cgggttggtt atcttcccgc cctgaaataa 2040 ataatagtcg aaaacatctg gctaggcaag cgttttgcct tttctttaca gcctcattca 2100 ctgattagtt taaattccgc ctcagggtga taaaggtcgg ccatatagcg ctttttgtaa 2160 tagaaagata cttccacaat gtggggcgct tcgatttcta tttgtgtgat agtcactaaa 2220 ccaggtttaa agcctggtgc aatgtccggt aattcgatga tcattccgcc ttttaaatct 2280 tttgctttta cagttctcat gatcattaac cttttttgcg tttcattact ttgattactt 2340 tcaggccttt ttgttctaaa aaatccgggc ggcgcaattg tgcggcgctg ctacggcttt 2400 taaccttgtt agacaacacg ccataatagc gcccgtcctc atgctgcccg atgaaataaa 2460 aatcatttac gccgtattcc tcatctcctg ccttctggat gatttcggct aatttgtcaa 2520 cactaatatt aatcataatt gctttacctc aaaggatagc ggggcgctag ccgccccggt 2580 ttgattattt ggttttgtat tcagcgatcc agcgggtgaa aatttgcgct tgcttttctg 2640 ctgcttcggc ggtgcggtgc tgcattactt caacatgcca acaatcagct agggtaaaac 2700 ctgatgcgtg agcggtccag ggatatgacg gatctttttc ttgatatgct ttcagcattg 2760 ccggatcctc gtggaaaacg tagggtttaa gctggctagc gttgtatgaa tcgccaccgt 2820 ttccaagttt ggcccactcg ttatggcttg atagatattt atccagcatt tcaaagaatt 2880 tagatttagt catttccgtt tacctcgttt tgtttagtga gtctgtatta tggggccttt 2940 cggccccgtt gtcaattagt ttaaatcaag atttagggcc agatcaacaa gggcggcgat 3000 ctgctgttcg ttagcgatgc ggcctacaac gtggcggata taaacacgga ttaataattc 3060 tttattgatt gcaaaacctg ggtgattcaa aagatctttt ttgcgaagtt tgtcctcagt 3120 ggcaagcgtc atcacgccgc ctttgtactc aatagagatc tgtaaaccat cggtaaaagt 3180 agccatgaaa taattttcaa aagcaacggt ttcaacgtgt aaacgtgcgc cttctttgtg 3240 ctgctgcata cacatagaac gatcataccc gaaagcgctg gcttgttcgt cgcggatgta 3300 gtaacggtca aagttagtta agcgcatgat gtttacctcg ttaagttgtt ttcgtttgtt 3360 tgccctacga gataaataat aatataagcg ggtatcgctg tcaatagacc tttacgtata 3420 tttacattat tcactttttg catctttatg catcgctatg caattgattt catggtgaaa 3480 ttacttttta gccgttttcc cgtgtcaagt tgtttttata tggcctttaa acgtcctgta 3540 tcgcgtttta agcggttttc cgtccaggct gtaccctagt ccattttatt ggagatctcg 3600 ccatattcac tattttgcat aagattttag gcgttgttga gagtaattct cattaatgga 3660 atagcgggca cctccggtgg ctttcctccg gtgtccatcg ttgccgcttc aaaaacagaa 3720 taacaaaaac caggaccgaa aacaagccct ggaattgtaa agattttgcc atcataccag 3780 gccggatctt ttcgcctttg caatgtcgga atataatttt ctaaagtatg ccgggcctcg 3840 atcgtttact tttacatatt catcacgcgc cgccacctgg agatcgtcgg gtaataatcc 3900 atgataacca ttgttaacaa tagcgatccg ttttttgttg caatcatagt aaacatatga 3960 tccatcggcc agataaattg tgcagttttg ccggatgtag ggtatcaaat aagcctcgcc 4020 ctggtgccgg attttgtaaa gcgccatttg tccattgtag atccggcgga cgtgataagg 4080 gtcattaatt gcccggtgaa tgttttcctt ccaggcctgg cgagcgttgc caacattacg 4140 gatcagtgct tccacctcgg ggatcacaac gttagcgcgg gcggcggctt ttgcctggtc 4200 tgataattca tcgtaataaa acattcgtac actaatcatt ttttaatccc catgaaagga 4260 aagcaagcca gatcggcggg gcgcaagtga tctacacgtc gccagccttt tgtcgtttca 4320 accaaaacac ggttttcaat ccagcgataa attttaccag atcgcatatt gagaaaacgt 4380 atcatttgca tttaccagta aaagttgccc cggcgatccg gggcctggtg tacactatgc 4440 cacaatggcg ggacggttta caacggtcgt ttttacgtcc tgataggtat catgtttttt 4500 aacggtagcc ctaaacttaa taaccgcgcc aaccgggcct aactcttttg atccgatgta 4560 ggtaaccaga tcgtcaccct ggcgaatttt tataatatag taagatgata aactccattc 4620 atcaattttc agataagaga aaataatctc accctcaaaa accaggcgat cgccaatgtt 4680 gccgatccaa ttgcttttta aatcctcggc tttacgctcg gcgcgttttt ggtcacgggc 4740 tgcaatgtaa ccatgatcaa gagcataacc caaacatgcc gcgcttaatg cttccattac 4800 cgggccgttg tctggcttgt ttgccatatc ggcaaaaaat aaaacatagg attctttaac 4860 atcggcaaac gttttaccgc aatgcttgcc aaacggaaag cgccccgctt cgatttcttc 4920 gatccgggcc gtatcgacga tcgacaattt accgcgacgt tgccccagct caaaatccgc 4980 atagcctgca aaaacttgct caaagttttc tgtattggcg atccgcgcgg ttactcgatc 5040 aaaatattcc tttgctttat tttctgcttt ttggggatcg gttgaaagat tgcaaatgta 5100 agaatctaca aaaacgccac cgccaaaatt acggcggcgc aatgtataca ttgcattcag 5160 ctttccggag tcgatgtaat aagtaacggt gattttagtg gtcattctgt ttacctcgtt 5220 ttgtgtggtt tttgtttcac ttgacaatgt gcgggtatct tatcccacac attaaccagt 5280 gccaacaaat tattcggcgg accatttacg ggcgtttttg cgattcaata aagcgacctg 5340 taagcaaaca cggcgggaat aattcaggcc ttccgctttc gcttgcaagg cgcgatcaaa 5400 ataatacttc gcttcttcgc ggcattcttg agcaaattgc tgggaaagtt tcatttcgtt 5460 tacctttatt ttgggccgtc gcaccattgc cgccctgtgc attaaatata ataaaagtcg 5520 cccacgtttg caagcgactt ttcagattaa ttttcccaat cagttagaac ggaaaacatc 5580 gttaacaata gcagttgtaa acatccagac tagatccggg gtagttatag gcaggctgtc 5640 agcctgtttt attgttactc cgcttctttc aagcgtgtag gcgataaaat gacggttttc 5700 aagtttcccg ctatgggatt gaatggattt ttcagtgcgg atcaggacag ttaaacggtc 5760 cgtttgttcg ctgtcattct catggcaaaa tactaacatg gttttttcac cctggcgatt 5820 aaagtcacaa ttgacattat cgttaacatt ttccagaaag aaaaatttgt ttgccttttc 5880 catactattt tacctttttc gcagcgggcc aatattgccc ggtccaagta atataaccta 5940 accgggccgg gggatcaata attatttttg ctttccggca tcggttcgac ttccggcgat 6000 ggtatgcagg ccggattaat ccagcgcccc tggcgctgat agtcaacggc gacgatctcg 6060 caagtcaatt gatcatcata gctttctact acataatcat cacactgttt taaggccagc 6120 gcactataaa aacacatacc cgcgaatact tcaaacatgt taaccgcctt attttttcag 6180 agtaatgatc gggcgcttgt caccctcttt gacgccagga tctaacgtat cgcagatccc 6240 aacttgctca ccctttttca aagtgtagct gttttcgtac acctcgcaag cttgttcgtc 6300 atcaaaaact ttctttacag tccaatcaca ttgtaatgac attgaactaa ccgagatatg 6360 gcaagctaat aaaataaatc cgaacatcac gccacctctt caacagtaga ttcccaggcc 6420 ccgtgataat caacgccgtt ttcggtgtcc tcatcacatg aatggatgtt atcaaaaagc 6480 aggccggatg tatagccttc attcaacatt tcgaaaattc tttcttgggc ttgctcttct 6540 aaaaaatcaa cgtggcggtc taatacttca ccgttattat ctgacttttt ccaccaataa 6600 gagattttga tttcgcgttt catttttcgg actccagaat aatatggata gcgacaaccg 6660 aacaagctgc cacgatgaaa gataccataa gcggcgcaga ttgcaagtta tttgttgatc 6720 tgatttgtct gattatagat cccatattga acacgggaca ctgtaacgga ttgagggagt 6780 aagcaacgaa cacgatccgc gcggttgtca tattttttga tatgcgccgg agtattgttg 6840 cgggtaaact taacacgcaa acgtaattta tttggatcgc ggtcatcgat tccggttacc 6900 acaccaaaag cgatttgacc atagttatga tacaccattt tacccaagaa ctttgattca 6960 agagcggcga tgttagattt tacgttttgc atgttgttta ccttttggtt gtttgtttca 7020 cttgtcaatg tgtaggaagt ataaccccac acattaacca gtgtcaactg ttataaacag 7080 aatttttcta gttctgactc acgaaaaagg aaattatcca ggccctttgc cacatttgag 7140 cattcaaaaa tccatttacc atttgaatct ttccaagcgc gattaatccc aacataacaa 7200 caaaattcag aactataggc cgttttatac atgttttgct tttccatagt gtttaccttt 7260 ttcagtgtgg cggtgaattc cgccactgat taaaggatag cataacgccg ccaggatgca 7320 acaaatattt ttaagaattg ttgagaactg ttctcatatg cagtgatgtg catagaaaat 7380 cgctgttatg caattagttt caaccggtaa ctaaattttc ggcgttttga gcggggcgcg 7440 gttatcggat accatctaaa acgccctcaa atcgattcta agcgcttcaa tgtgtaaccc 7500 tggtaagtgc attgctacgc tgagatctcg ccatattcac tattttgcat aaaaaagccg 7560 gggagttgtc cccggcctgg ttattcacct gctacggcgt atcgctgcaa attacgttta 7620 cgatccgcaa ggcgtttatt taacttcgga tcatactggt ccggcgacca ttgaaccgcg 7680 atccgttccg gcttatgccg tttattgtta cgctcgcgcc gctcgttagt ctcaccaaaa 7740 gcaaggcgat cgcgctggct tgtcatcttc tcaaagttgc ggctttttgc tgtcatatct 7800 tgatcccctg tggttgtatg tttccgctcg ccattctgcg atctgttttt tgcgatattc 7860 gatcagctct tcgatgtagt cgaaggatcc ctctttatgt accaggacca cgccgccccg 7920 gtgtttaatc tcacatatca ggccgctacc ctccagatca ttcaacggcc cggatcgcct 7980 ggtgtggtaa tcctccccct ggaagcgata ttctatatag tggaacattg ttttaaccct 8040 gtaccagtag taaaaccatt ttataacacg ccaggatctg gcgtgtattt ttgcataata 8100 acaaaatatg agtagaatca acaattcttt catattacgc ggcgctgttt ttaaatggct 8160 tatcccacga tccgaactgt agatcgatat agtgacccac attaaaatag tctgtcatga 8220 tgtcgcttct atcataattg tcagtgttta gcgcgttgat gattttttca agcgttgcgg 8280 taaactcttt atcactcgaa taagtatgag catgataatg gttaatgccg agatatgtaa 8340 agccgtccgg gtatccttct ttaactgatt tatgatccat tttagacaca agatcaaacg 8400 gcgcggatcg gatagtgcaa acaatagttg aatagtgacg gatcgcaaat gttgctttcc 8460 aaccttttgg caatacagct ttaaccgctt caacaatttt cgctttcttc tctttattca 8520 tgtaagccat gataaaccgc cttttgtttg cttgtctggt atatgcgcca ccttatcagg 8580 aggcggcgcg gatgtcaatc aaatgatttc ggtaacgtct gaatatttga tcgtgaatgt 8640 gctgttttgg tgacctggcg ccacaccagc aaggcgaccg taaaaagata cgcggttttt 8700 aacgccttca aaaatccacg tcctgccacc gatacgcaag cgggaaccga tagccagcgc 8760 tttgatctgt tttggtgtag ggttttgatt gtcctctaca acgtgccagc ctgccgccgt 8820 taaatcccca gggcggctac cgcgccactc ctgattgatc aaggtaaaat gccataagcg 8880 ccccaaataa taataaaact gttttcttac agctacatat tcaccgtgat agccttcttt 8940 cgcccatata tccatctttt tattgtattc aacctcgcca caaaagatcc caaaatagct 9000 aacctggttg aatgtgcgcg gggaaagcat gttagaagtc agttgtttag tattcagagc 9060 catgacagtt tacctcgttt ttgtagggcg ggacctattc ccgccttgag tagaattatc 9120 ggcctttcgg cctagcttgt caaatgatac gttcgaattt atcgaatctt tttgcggatc 9180 tgccgtgaac gtcgatcacg acgttggcgc gtttaccatc gcataagccg caatctaagc 9240 agctaatatt gtgagtggta ttaacgcaag tgatctcccc ttccaggcgt cgcatattgg 9300 gagttttcac gcggaaagtt ttataaccct tgcgccatgc tgtgatcgct tgcttttccg 9360 tatcagcgga gatctggcaa atagtagcga tccgatggtc aaaattttta tggtggagct 9420 ggtgagtata acccgtgttg ccttgcgtat ggttgaccat gttttgccat acctcaaaag 9480 ggaccgccgc aggatcaccg taggaaccta aacgaatatg acgacccgca aaatgtacca 9540 gatcgcgaga atcaagatct ttatagttgc cttttttgta agacttccag actgccagcg 9600 gggcctggtg tagcgttaca taacaagcgc cgtttaagct ggtacgatgg ggacacatac 9660 cgcaaacaga tgaatcaagt tttttagcgc tcgcttccag tgggctaaca tcttcccgca 9720 tgatccaggt ctggatcata tcgccggttt tatcgttagc ggttgacatt gtagcaatga 9780 ccacgatcgg ggccttatcc agaactgacg ggcctttata taatacataa cccttttttg 9840 ctgtggattt tttacccggt acactatgca cgatctcgga ttctgagttg acaaccagac 9900 cattattaag tttaaacgta gacattgctt tttacctcga tttatcgcgg cccttgccgc 9960 ctgagaaaac actttatcaa aggcgctaac tgaaagcaag cgcccaggat aaaatatttt 10020 atttagccag ggataaggtt ttgccgtggt tgatcccagg gataacccat tgcccggcgc 10080 catctttaac aggttgacgt aaacgcgccg ccgtggttac cttgctgtta acattacggg 10140 caaaagcgcg ggcctggtca cgggtagtaa aagaaatatt tttcatgttg taacctcgat 10200 ttgtgtggtt ttttgttttg attgtcaggt ccggggattg taaccccgga cactagccag 10260 tgtcaattaa atatttattc ttcttcttcg ggatctccat atgcactatg gatcggagtc 10320 tggcaattac cacatgggaa atcctcacct tcccagaaaa tacccacatc ggctggcatc 10380 catgccagat cactcccatc tcttaattct tccaataggc gggtaaaatt ttcatgcgta 10440 cactttgagc aaaggcaacc accatcacgc ataattaaaa ttttcggata cccaccgaac 10500 tcatacgggt ggcggatata attttttaca gtgtcgatca attgtttgtt agcggaaatt 10560 ttcattctat tttacctttt aagtgtgggc gacgtggcga cctgatgaga tgaatagtaa 10620 gcgctttacc aattgccgtc aatacctgga tgcaaatatt tttctaaatt tttcgcttgc 10680 gttttccctt cattagtata tagtagttat caagccgcca cggtggaggc ataacgagga 10740 tcgggcaatg accaaaacag aaaaactcac tcttgaaata gctattaaac acggtttcac 10800 ttttagcaat gattcacatt tcaccagtta tacagcagct cgccgggcaa taacgggctt 10860 gattaagaaa ggttttcttg tgcaggtgga tgacggaaac ggcgtagaat accagcctac 10920 acaagccgcc agggatttta tcaaatatgg tgtttaatgt gttgacacgc cccagggaat 10980 ggggcatact gtatccatac aggagaggaa acgcctacca acggcgctaa acttgggtga 11040 tggtagccgc agggcatcga cagctataat cgccggtagc tcgcctaaag tctatttgta 11100 aagaattgta aagacgcttg caacctgggg ccgtgtatcc tatattatac acatagcggg 11160 aacattgaaa ccggagtaca aaacaccggg ggtgcctgtt atttagcaaa tgagaatgat 11220 tatcattcaa ataactaaat aagaatgctt ctcattcaac aaaaaattta aatattgact 11280 tctgattttt catgtgagat actgagcgat acccctaaaa aattttttcg cgtaagaaaa 11340 caaatacgat cttgaaattg agatctcgat cgagaaccgg gccgaaaaat tttttctaga 11400 gaaaaaacaa ttacgatctc gattttgaaa aaccgatcga gaacccggtt gatatagaga 11460 aaaatttttt gatagtgaga gcaaatacgt ttttgaaaac gaaaagtcga tcgagaaccc 11520 agagttttct acctgaaaat ttgagatatc tttttcgcct atttgagata aatgtccaat 11580 cttgatgcca agatacctat agcaatcata cgcttgtgca tcatttttcg acatagctcc 11640 cgcaaaggtt tgagataatc tactcccaaa actcttgatt taaaaatttg cagggaagat 11700 gaaatccatt tcaaaaacga ttttgaaaac catttcgaat tttaaaatat ctttgggata 11760 ttaaatatca tacaaatatc acacagtttt gaatcttatc tcggactgaa aatcactttc 11820 cattttaaaa tatcataggt tgtacctgta gaaatctcat acatttgaat ctcatctgga 11880 gtcggattac aaatgtcaat gaaaaatgtg ctcaatacag aaatcaggaa ccgttctgtc 11940 tttcctggga ctgtgtaaac aatacgcata tcaccgggaa taggagaaag gaccaaggaa 12000 gtagggccat tcataagtgt aacggtatta tcagaaatct tgatacgacc atcgacacca 12060 tacaccaaat catgagcaga agaataatgt gcaagcacct ctactaccgg gttaccgaca 12120 aggttcacga ggtaatcaag atacaggtct cgccatcctc gattctgcat catgtaccgt 12180 atatgggagc ctccatcaaa catctcaccc agttgctctg cgatccaggc aacaccattt 12240 gcaatgtctt ctctgttcca ggtattgtcg atatctaaga tatccttgct gaacttgttc 12300 atgcgccgca tggcattgag tacatactca cctctttcaa caaaggcacg ttcagtgtcc 12360 ttggcataat cgagaagccc ttcaacctct gaacctgtag cgtattgctt aaggtcatca 12420 agcacacttt ccacgctggc cttggcctga ttgaaagtca tctcatcagt ctcgtcatta 12480 gagaattcta caccaccaag ggcatatact gcatcaaggt aaagcctttc aaggtcgctg 12540 cgcacgttag gaaaatcata actaaccttg ttatggggga taagttcgag agtgtttaaa 12600 atagtggtca ttgtatatcg tcctgtaatc aatcctgagg cgttttatgc aaaggcagta 12660 cgtttgccta ccttatgtgc taaaaacccc gctacggcgt ttctacgcat catacggggc 12720 atcatagcat ctgtttttca gtcacgtttc atttggtagc gcatatacgc catattcatc 12780 ttgtgtttga catcgaaagt taccgggagg tttccaaaca ccaggtagca gacatcatac 12840 atgatctccc agaacttaaa aaccaaatat ttagaccgtt tttctaagct catcatctca 12900 cctccacagg ttcaataaaa tagttctgac cttgttttgt ttgacaaaat gaaccaacgt 12960 accagacacc ggaaccacca tgtgggtgct acggaggata tcatatccgc gaagcttttc 13020 cgctttttgg acattttctg gtgcatcgac tatcttcatc agcaaatcaa aaccagacat 13080 cgacatcagg aacttgttcc caccttgatc gaccatttcg atattagcag cagaacgacc 13140 acgactgaat ccagtgtact ggagtttcag ctcgcgaatt tcatgacgat cggaaacatc 13200 caccttatct tccatcttcc agtcatgggc atacccggta taccaagcat tactgccttt 13260 gaggtatagt gcgggatatc cacgctttcc taacttagcc atatctcacc tcctgtggcg 13320 ctgccggcag cggcatccag tgagttggtg tccatgacgc gccggggatc aaccagccgc 13380 tactctgcga atctgggtgg ccagggatat acgttgccca tttgcaacac caccgcggct 13440 tctctcccca ccaacgcccg accaaaacct catgacgact tggcggcatc tgctcgctta 13500 cctgaatcca tccctggctt tgcgctggag tgtcgccgtt ttgcgccggg cagcaatcgg 13560 attgcgccgg agagttgcca ggatgcagca tggcggcgcg gcaggattca tacttcgcca 13620 tcacgaccaa aacgccatga ttccatgcat gctcatcaat tgagtcgcac gttttacatt 13680 cttcaattgc cgcttcgaat atcgacacat catccggcac taccggagag ttgccagcct 13740 cataagctac gcgcatccag tgataaaaag cttctgcggt aacacagccg caatctactt 13800 caataacccc atcttgttgc gataaccatt cttcgaattt catggcttac cctcgttctt 13860 ttcaatacca aggatcatgc cctggagttg ctgtttcatt ggaatcagga ttggcatatc 13920 atcaatccag acatctggtg tccagccgtt ttctgcacac acttgggcct tttgtacacc 13980 actacagtaa attaccttga tatccatctc tttagcccag aattcaatat ccgcattatc 14040 atcagttgga tatcgaaagg taacgaaacg aacatcaaaa tcaccttcga tgatcatcag 14100 gtcaacaatg tgttgccaca tggttggatt taacgtgaaa gtatcatcaa agtcaagtgc 14160 tatccgccta cgatcaaata gtttcatttg cacctttttt actctcttgt tcttcaaaga 14220 agagttgatc tgccagatta ttcaggtggt ttgccacctg acgggcctga gtacgagtga 14280 gacggatgcc tgcattgtca cgatcatcgt tggtcttatc cgtcatccag agttggatca 14340 gaaccattcc tggattacag caagattcca taacttctgc tcgaccacgg taaaattcag 14400 tatcctcttc aacctctaag tatttttcca ttattgctta tcctccgcct tagatttctc 14460 tgccttttct tttttcgtag tggcatcaag ctcatcagta tatttcttga tttgagcatc 14520 aagatactta atggtgctat cagccagttg ttgtgtacgt ggtgactcaa ccacattctg 14580 acctacatac gccgcaagca ttttatatgc tgtttctttc tgtggcataa agttagcgta 14640 caggatacct aggaaacata caaccatgcc aaagactgcg atcttacgtg gacctttggt 14700 aacatccttt accacaacag gtgttgttga ttggctctcc ttccgggtta ctttataaat 14760 tgtggactgc ttaatatagt tgctggagag ctttccatca ggcaagcgaa ctcgaagtgt 14820 attatcactg ttccataccg taacgatctc aatcgtatcc ccggccttat atccactcca 14880 gtcttggtta agaaccagat tttcaccttc gaagaactga taccctaagg ctgtaccatt 14940 cttctcaaga tcttcataaa tcttctgacc gaaatagcag gcggcgtatg cgagagcaga 15000 gataaacatc agagcaaccc aaccaccata attaccgtct gtagtaagaa catcaatcac 15060 ataaatcaga aaaggccatg aacccatttt gtaatctcct cttaagataa ctttagttaa 15120 gtgttaaatt tccaacagtt tcgatgaagc cgaagggcat ggaaaatacc ttcaccatat 15180 aaatcttgtc cttaccatct tcatagtaag gcacaactac aacatcatca gctcccagag 15240 gaagcatagt cataatcata ccagaatcta caacgtattc aagcacagct tctttggtgg 15300 caggaatttc tttctctgtt tgtttgcttt ccaacaggcc accacggtgt tgacgaatac 15360 ggattgtttt catttatttt ctctccagcg ttgcgggttt ttcttcattg aatgcttggc 15420 ggatgcccat atcgtatcca acacggagaa tctctctttc gatcaggaac tctatatcgt 15480 gttttaactt atcatatacc gcatcaggaa gtctttcaac aacccagctt gcaccttgag 15540 agagagtaag ttttgccatt ttcttgtcgg ctcgcgccgc ccccagttaa tcgtcgcatt 15600 tagaagctcc tgtcgcccgt ggctccgaac acattgcact tccacacaca tctaacaccc 15660 gtaaacgggt tagctcatag ctaatccact tgtggatgac tgaagtgact catcacttcc 15720 tcttgaaact aactatacac taactaaacc atagatcaag atctttttat aaagatctat 15780 gttttaggtt ttaagatctt atgtgtatta ttttatatat gtattcatgt gcaaaatttg 15840 catgacacga gacgcaaaat ttgcatcaca acacggtata ctcatacgta ctcatccctc 15900 tgcgttctgt cgatagatac cctagtgcca cgaggttttt tatggatgtg ctgattgacc 15960 tttcagacac acccgtagct tcactaatcg ttttataact agcaaagtat ttcttccctt 16020 ttgtctctaa gtatcctgcc ttgtacttta tgtggagcag gacacgaaga tctgtgcatg 16080 acaggttctt atcatgcagc tctttttcgt cacaagctac ccacttctca ctcttttttg 16140 gcatccaagt atttctccaa atgagtgagt acaacctctt gggcatactc ttgagatgca 16200 tcattgtggt gaagaacagc cagatcacat ccaagtttgt gcaaacttct ctcgaatgga 16260 gacaagtgtg tcatcataac ttcgaccaga ctaagctctt cttctgtgat gtggagggga 16320 tcatccgtga aatccctgga gatgagaatc tccctctcac caccttctcc ggcaccatat 16380 acctcgacaa tcttcctgtt acagaaaatg tcatacctat agccagtcag atcatgacca 16440 tcttgtactt caaagttcac aatgagacaa caaccaagcc ccatcaagta aacctcaaaa 16500 tctaaattgt ggacaatttg catactcacc tcgtaattcc gtgattttca tggaaattat 16560 actctttgtt agcaattttt ctagccgtta tggcatcctc taggagatca aacctcccta 16620 agaatttcgt ttttccatct acccttatat acgataccca tttatttctg ctctcttccc 16680 aacgaacccc cgtcaccccc gatttatttt taatattaat tttaaggttc ctcccattac 16740 cttttacagt cgtaagtcgg agattatcca atctattatt agacctatca tgatcgatgt 16800 ggtcgatgac cataccttct gggatggatc catgtaccat tatccatatt gccctatggc 16860 aatcaatacg tacatagtct atacaaagtc ttctatagcc attcttatcg attcttcccg 16920 ccacatctcc agccttaatg actgtattct tttttgattt tttccagtac aaattgcccg 16980 tttccgggca gtaggtaagt aattcatcca ggattttctt atttaaagtg ttcatctaga 17040 tccacagctt tcccaaatgg cggaatccaa cccttgcgcc caccacagat aacccagaga 17100 gtgttgtact tacgccccca gcttgcgcca cgatgtctca ggtcctctat gtaaccatct 17160 gtgaagatta taacctcttt tgccttagga ataaactcat cgatgtactc aaatgcacat 17220 gcggcagttg ttccaccagt tgatgtaact ctataatcca gaatttcctt tatgttgtcc 17280 tgtgtgtaca cgttgacgtt gccaacttgg gttgaccaac agaacaatgt gatacggaaa 17340 cattggtaca gggtgctcaa agcgattatc tcattgaaga tacgcgtcat tgtttgacga 17400 gagatagaac ctgaaacgtc aaaaccgatt acaatatcaa cagtctctgt tctttttctg 17460 ccaggcataa ccatgaactg tctcttagtt agagcgccgt gatcacgaag gacttttgtc 17520 attccccctg atcgacgacc taagacccgg taagtacgat cagatttaac acgagaaatc 17580 attcgttgtt taattatttg caggtaatta atcttcggtt tacctttttg tgcgattaat 17640 tctctggctt ctttcggtcc ttcaccgcct gcggctttca tagcagcgtc aatcatgtcc 17700 tcagaccaag acatatcctc atcttcctga tcagcagact tctgtgggtg tgggtccgta 17760 taccccagga tgtccaggtc tttatcataa tccccgatgt gcgcccccag cggcttacct 17820 ttaccatcac cagcctcatc cggcaacaga gcataaatct cttcagccgt tttcccctcg 17880 tactgatagt cacaatagca gtaagcaagg aatccaaatt cttttgtctt atcaaagact 17940 tgccgatgag tgaaccattt caaactctcg gctttctggc ccaactcctt gaccaggtcg 18000 gtgttgatat agtgatcggc tgcgatattg aaacgtctac ggtcaaatgt tttcccacga 18060 gacatatggt cgttggtgac atggcggacc tcatgcatta gaataaatac aatttccttc 18120 atggtttttt gacgatagaa gacatcaaca tattctttat attcatcttt ttgctgttgt 18180 gtcatcatcg gatgcttgtc aatacgagca aaaacctttt tcttgcgatc aacaggcata 18240 cccataatga actctgggtt aaagtatagg ttgcgatgat cagtcgctgc ggttggaagc 18300 catgcacagt caactatcag cggcataccg cttaatagcg tcccgtagaa tggtcgatta 18360 gtaagtaaag cgatgcgggc agactgaact ttcttcagtg cttcatcagc cagttccata 18420 atgctttctt tttcatctat atacattctt atctccaaga aaaaaggcca tcagttacga 18480 tggccttatt atatgttaat tcatcaccct ttgcaatgca atttggggta aaaattcatc 18540 tatcccttca atcctgaaac cccaggccaa ttgcggaccc ggcgctccag gaaggtgagg 18600 aacagcaaac aagacgatcc catcaatagc tccgcgaatc gcgttctctg tgaaagtctc 18660 taccagatcc ccgaaactaa gacccggcct gaagccagca ttcagcattt tttgctctgg 18720 tgcggatgca ggcctgccca agatatcctc gtacattaca ccaccttgtt cagcattgct 18780 gtaactttag gcaggctaag acccgtctgg atcatcagtt gagtcatagc agtttccatt 18840 ttcttggaga cgatgatgaa attatctttg gcaaagccaa tgttaagatc cagaatcaga 18900 atggatttag gctcaccagt aagcttctct ccggtcattg cacaggtgct gcgaatatat 18960 ttggccttga actgagcata tgtcacactt actttcatac cgacatttgc aaaagtattg 19020 cagtaatttg cataagcaag cgcaacagct acatcttctg gcagtgcaac actgatagct 19080 tctttcggtt cagcctccac ttccacaggc gcagtggttt cttctgccgc aggcagttgt 19140 ttgtgttcgt gttcagcaag ctctttgtag tcggtgttgt gattcttttc tacttctgcc 19200 atgtgttctt tcatgtccat ttttgtctcc tgttgtggga tatatttagt tttcagtttt 19260 tcgagatggt ctttagacat attcagcatc atagcctgca caatctcacg gtctagcgga 19320 tcaattatag tgatggctgt tttcttgtca accaaacgat ctttcaattc attggctctt 19380 tgcaagacaa cgcatacatt tccacgaaca taacctttct tatcgtcaat gcgctcaact 19440 gtcggataca atgggtcttt ttcgccatgt accgacctcg tgctaaagtt catattggtg 19500 tagtcgcacg ggccgatgcc caaaagcttt tctcccatca tgaaccagtc atcaagggtc 19560 aaggagaatt ctaaaccccg tttctttgtg cgttctacct ttttatgata ccgttcttct 19620 agacttttaa tctcgctgtt ggtaaatttc tttttaacat caaacatttc taactccttg 19680 ggtcttaccc gttcttagta aggtgattat caccattcgg aaaagagttg tcaacccttg 19740 atttctaaaa agtggcggtg tatctttgtt cattatttgt ataagagggt aagtgagatt 19800 atgagcaaag tagatattaa tgtaaaacca aacgagactt ggaatgagga gcgggatttc 19860 atagataagt tgttacaagg gaagcaggct gctcaagaga gatttctttc aacttttgag 19920 agggacagac atgttgacaa tcctatcacc cgctttagag attatcttca aggggtacag 19980 gattcgaacc ccatattgga catatttttg tcatgtctcc ataaactccc ggcgcatggt 20040 ggcccttttt attggcaatg gcattccggt gatgtccggg agtatggttc tgatatgagt 20100 cagaagctaa atgtttcacg tatggaaata ggccaccaat cacatattac gggtggtgac 20160 ccttggacac atcgctttgt agaaacaatc tccatcgata tttatggtca cggttgcggt 20220 gaagcatttc ttggtgggtt ctgcaatttt aactaccgta ctaagtattt tcttgagtgt 20280 gtaaagcagc ttttggtggg gatgtcacac aaagatgacc ttgatctccg tttggttgtc 20340 gaatatacca gctatcaaaa aaatgcccct gtccaatctt ggatggccca taatggggag 20400 agattaaccc ttaaaaatgt aagcctcatc agtggtgatt tggttcttta ctctgactat 20460 cttgagcctt ccgcattaga tcgtatttgt agccaaataa atcattctgt tatcaacatc 20520 atgaacagaa agatcgctaa taaggcacgt aaggcaatgt ttgtttgttc tccgaaagaa 20580 acgatgttcc acttggaata tgaccccaag ttacagagta tgatggaggg ggactccccg 20640 acagaagaag aactcatgat gatgtctatt gcagggtatg aagatgagtt ttggcttgac 20700 aacgtaaaat ctttcgatag actgaacata aaacccttta acctagagga agctgtcaaa 20760 tggtatcaac agacaagagt tgtattcaag ctttaagtcc ggcacaagaa cttgctttag 20820 caattaaaat tgcagcagaa ggccacctga atcagaaaga taagggtggt aacccataca 20880 tccttcaccc tctgaaggta atgcactatc tgaagactga tgattttcag cttatggcta 20940 ttgccgccct acacgatgtg gtggaagata ctgatgtgac cgctgcggat ctggttctgc 21000 taggcttctc gaaccgtgtg aaggatgctg tggttcttct gacgaaaacc cctaatcaga 21060 caccggaaga gtattttaac cgcctggccc aaaactatga tgcggtacgt gtgaagcttg 21120 cagacctgcg ccataactct gatgttcgtc gtctgaaagg tctgacagat aaggatttgt 21180 tacgtgtccg taagtatcat gacatgtatc ttcgtctgac aaagatgaaa gaacaccacg 21240 aagcgatcaa catgttggct acattatgat cattacgaaa aaatcaaatg gccttccttg 21300 gttcgaaatg gaaattcctg acaaggttgt agtatgtgcg agatgttttt cgacttataa 21360 cctgaaagat gctcctgtaa aggcccccga tcagcttcgg attaaggaac cttgttgtcc 21420 gaactgtggt tttaaatggt atttgtcatg aatctctttg tatgaagaca aatcaaaccc 21480 agcccttgaa ataaaacttg gagaacttta atggctaact ggaaaacagc tctggaccta 21540 cgtgacatct ggaataaacg gaatggtgaa tgtggtcggg aagactggac agataagacg 21600 gtgcatgagc ttgctaaaga gatatcccgt cgtcttgaac ggaaatttcc tcatgaatca 21660 aactatgata gcgacctctg cgataccgag ttgtgtgata taattggcta tttccgggat 21720 gttccaacat accaggattg gctagactct attgcagaat gtgagagtga ggggtatgat 21780 gccgacccaa tccgctatta tacacctttg cgggaattca acgacatcat gaatgatttt 21840 tatgattggt gtgatgaaaa tcgtgtatgg gtggataaat aatcattgca atgggggagg 21900 atcaaatgta tcctgctccc gaatttcatt tacaggagac aaataatgtc aagtcgcaac 21960 atcttttctg gtaactggat cactttgaga gatcttccac cactggtgca attttgccag 22020 cgtcacaaac gttcactgat gatcttcggt ggggcaggta ttggtaaaag tcaagctgtg 22080 aagcaaattg cggattctct tttcgggccg ggtgataact tggtagactt ccgcttggct 22140 gataaagata acactgacct caccggggtg cagattccat acaccgatga caatggtgtt 22200 actcgcacag tgtacgcctt gccggatttc tggcctcgtg atcctaactg gaaaggtatt 22260 gtgtttcttg atgagcttct ccacgcagag ccttaccttc agaaactggc attccaaatc 22320 atgctggacc gtcgaatcgg gacctaccag ttccctgaag gggctgtact ggttgctgcg 22380 ggtaaccgtg ctggggatgg tactgccgtg actgcactgg aagctccttt ggctaaccgt 22440 atgatgctgg tagagcttac ctatagcgca tcggtcttca tcgaagacta tgccatgcag 22500 aacggtattc attcgtcaat cattggtttt ctgtctcgta agaacagtgc tattgaaaac 22560 tatgaagaga tgctggatat cgggtgtcct tctttcgcca caccgcgtac tttaacttac 22620 gccagtgatg tattgtacga ttacgatgct aatttgctgc ctgccaactt ggctaaggtt 22680 gctctccagg gcttcatcgg tacaccttta atggctgaac tgtgggcata ccacaccaag 22740 atccgtaata tggttccgat cgaagacgtt atgaacggta ctgcccaagg tcctggagac 22800 cttccatcag acagcctgtg gattttgggt tcagaaggtg ctatttggtt gcgtaaggct 22860 attgcagata ccaattacac ggatgaccag attattgaat tctctggaaa cttccttcag 22920 tatctttacg atcactttat ggaccagaac cgagacttcg taagctctat cttcctgtcg 22980 ttcattaagg aaaatgcgtt tggtaaagct ttgttgacca ctgcgagcaa ccgtgacaag 23040 cttcctgcac gtttgttgaa ggcaaagcct atcataatga aaattatggc agacttccag 23100 gtcaactacg ctgaagatat taagcttatt gaaggaaaat aatattgaca gcccctccgg 23160 gggctgttat gctttatgca tcaaacaaaa cgaggatata ctcatgccga aattaaactg 23220 gaaagaagca cagcaggcta tgcgtgaagg taaacgtatc cgtaaccaat atttcacttc 23280 tgatgaatgg ttcgaaatgg ttgatgggcg tatctacgca gaagacggtt gccctatggc 23340 aggctggtat cgtggtgaat catggcagga tgaaggctgg agtgtgatcg aatgatctac 23400 aaaaaccaac tccgcaatat ctggcgcaag tttgttaacg gtaaaggcta tgtgtctggt 23460 gaccaaggcc tcacctggac agaaaatggt gctcctgagg acttgatcaa gcgattacct 23520 tattacgtgg agagaaagga tggcaaaatt caaattccca gtttctgaac taaacgagtg 23580 ttggtggctt gacaccgccg actgtgttat ggcaggatac acctatcgac gtcatcgggt 23640 gtttgttgtc tgcgcgaaaa atcgttcgga tgctattgaa tccatgaaag agtttaaaga 23700 gaggagttgt aaatgaaagt taaaatgacc gcaagttaca gcgaacaagg acacgccccc 23760 caaaaaggtg atattctgga tgttctggag gaagtgtata atgggacatt tattgactat 23820 taccgttgtg agtggaaagg ccaagacctc gatatctatc catacgaatg tgaggaagtg 23880 cgatgacgat tcttgatgat tcaaaaccga aacaggtatc aatcctgaca attgttgggc 23940 gggttgcaac attctcatgt gacgactttg atatagagat cattggagaa catcacgtca 24000 tcacaatgaa ggttcctgac cctggtggtt ataaaaaggt taaggctcaa taccttatcg 24060 agcctatcat gagcatactg aacgaggatt actaatgaag gagagtgaag aggcattaca 24120 ggcgcttaaa tcttccttct catatgaccc tgagacaggt ttttttacgt gtatcaatcc 24180 tctcgctcgt cgttattttg ggaagattgc aggcacaaaa agaaaagacg gctacattgg 24240 acttgctgta acgattgatg gaaaattgaa aatcttctta gcacacaggg tcgcttgggt 24300 ctttcatttt ggcgtttggc cttctcattt tattgaccac aaagataaaa ttaaagacaa 24360 caatcgtatt gacaatttaa gggatgtcaa aaagtcggta aacgtctata actatagcag 24420 gggcaagaag aaccagacag gtttccgtgg tgtgtttata gatcgcaggc gagagcctgt 24480 aaagtataat gctgcttatg gcaagaagca tcttgggact ttcaataccc cagaagaggc 24540 aagcgcttgt taccaaaact atgttaaaac tattcatgaa attgtggtgg aggactgatg 24600 ttcaaatata aggttgggga tttaatagag gcggtaaaga gtggcgaaat aaatgttttt 24660 ggacacggtg caaattgttt ttgcacaatg gggagcggaa tcgccccgtt gatcaaagaa 24720 gcattcccta agatgtacgc tgccgatctg aaaactgaga agggcgataa gaccaagctg 24780 ggaacctgta caatggcctt tttgaatgat ggatctctcg caggatttaa tctgtattcg 24840 caatacggct ataatcgtcg taaacagggt ctcagggacc tcgattacaa tgccctgtac 24900 gattcgatgg ttgagatgaa aaagctctta cagagctata cagacggttc tatggctgac 24960 tacaaaattg gcttccctaa aattggtgcg ggccttgcag gtggggactg gaatgtcatc 25020 gaagcaatga tcaaatcaat cttctttgat tgcgatgtga cagtttatgt cttgaaagaa 25080 tgggaaatcc ctggttacta cccttcagac gacggccctc tgacatcaga acagatctct 25140 gccattcggg aaatgacaaa atgtggatta tccacagggg ggactggatt atcgtggtta 25200 aattgagaga cggtatggta gcacatacca aaaagatcga cctttatgtg ggtaatacgg 25260 tgttaaccta taacgcccct cgtggtcaga gctttgccat actactactt ggggtagaga 25320 aaccaagtgg tgacggcacg ggtattcaga ttgacgaatg gctgaatagt cgtggctgga 25380 agctggaggg tcctgatgag taaatcggtt tttgtcatct atgacactgt tgacagatgc 25440 ctctggaacc acaaagccaa gattggatgg attagctctg gcgctgccaa gaatgcgtgg 25500 aatcttgtcc acgcaacctg gagtgggaag aagtattttg atgaccaaca aagatatgta 25560 gttcttgaac tttctggcgg acacattagc aaattatttg aggagaataa aattgacaaa 25620 accaattaaa tacccaagca ccgcacagtt ccgtcaggtt atccgcacca tgcatgataa 25680 actgacgttc gacggtattg atgaagaggg taatattaag cggaaggtgt tgccaccgga 25740 agcgtacctg atcccgtaca tcggtacggt taagcttcac ggcactaatg gcagtgtggt 25800 attccactct gaggatgaag ttgtcttcca gtccaaagag cgtgtcgtga ctgtaggcga 25860 cgataacaat ggcttcgcgg ccttcatgtc tcgaaaagac accgcagagt tgctttctca 25920 ggttaaatat ctgtgtgaag tcaatgacgt tgagttccag ttcccggttg aaattgctgg 25980 tgaatgggct ggtcgtggca ttcagaaagg tgttgccatc actgaagtag agccattctt 26040 tgctatcttc cgtgtggctg tgggccggga tgaggcaacg gataccctca actggctacc 26100 accaacgttc cagtttggaa ttggattgcc ggatgctcgt atctacagta tccttgactt 26160 tggttactgg atggctaata tcccattcaa tgagccggaa cttgtccaga atgacctggc 26220 agaactgact cgtgaagtgg aaaacaaatg cccggcaggt aagttctttg gcgtagaagg 26280 tatcggtgaa ggcattgtct ggtctccaaa agatcctgag ctttctaaaa tctctggcct 26340 gtggtttaaa gttaagggtg ataaacattc tgtatccaaa gttaagaccc tggcggcaat 26400 cgacccagaa cgcctcgcaa gtatgcgtga gttcgttgag tacgctgtga cggaagcacg 26460 tcttgagcag ggtgtcagcg aagtcggtct tgaccagact aagatcggtg aattcattgg 26520 gtggattaac cgagacatca acaaggaaga gggtgatgtt ctggaagcca gctccatgac 26580 catgaaagat gttggcaagt ttatcagcaa caaagctcgt gcatggtaca tgactcgtct 26640 gagtgaggag ggctaatggc cctcattgta gccacaacgc ggtctgttga aaaaagacct 26700 ggacattctt tcaccgagtg tgataccttg attttcgaag acgaagaaca gggcaaaaag 26760 tttgttaaag agaacaaaca gtttgtctat catgtccaaa aagcgagggt cattaagaat 26820 ggtgagacca gaaccgaagt ttaaagtcgg gcagatagcc aaagatactt ggagcggcaa 26880 gataggtcct atttcaacca tgtacttttc agaaggggat gagtacaaca aggccgaatg 26940 ggcatattct atagaccata tcgggtggtt attccatcca gagtcggact tggaggcggt 27000 ttaatgggtc tgcgtgaata cttagcagtg aaattaaaac atgcaaagga gcaatctatg 27060 gttaaagtga atggtaatac catcactatc aatgggaata ccgtggttaa tggtagcatt 27120 attggtgggg acttgagtat ttctgcaaat ggggataaaa tcctcatcaa cggaaaagag 27180 gtctacgcca cttctgataa aaacatcatt gtggtcatcc acgggaatac cgggagcata 27240 aacaccacat ctggggatgt gaaggtgtat ggcacagcag gtaatgttaa gactgtttct 27300 ggtgatgtcc gtatcgaaac agggtcactt gcagatgtga ccaccgtctc gggagacgtt 27360 atagcagaaa ccattgaagg taatgttaga acagtctcag gagatgtctc tcaccgtcgt 27420 tgatatacag ccccgcaatg gggcttttta atttggagtg taaatttgaa attgaaaaat 27480 ctgattctgg caaccgcctg tgtgttttct ctagccacca cacctgtact ggctaaagac 27540 aacgcaaaga agcccaaagt tatccatctt tgtaagaagg atgacacagc ggtaaacatc 27600 ttagcatgta atatgtatcg agaggctcgt ggagaaagcg attccgggtt aatgtcgatc 27660 gcattcgtaa ctttgaatcg taaggataac gataagtacc ctgggacggt aaagaagatc 27720 gtctaccagc ccggacaatt ctcctggaca tcttcaggaa caacgtttaa agtctatgaa 27780 aaggatcgct gggagaaggc acaagagttt gcaaaagttc tgatcaagat tcataaacaa 27840 aacagggtcg tctacgatgc tctggacata acacacgggg ccactcacta ccattcacga 27900 aaagtaaaac cctactggac aaaggccatg ctacgcacag tcaggatcga caaccatatc 27960 tattataaag agaaagaaga ctctcagggg gcatgaactc atgaagaaat tcttggtaat 28020 atttgtttgc attacccctc tgtgtgtgat attgtcactg tcacagccca tgtattggga 28080 acaaatttgt ggagcatacg caataggtat ggctacagcg gcctttagac taaatacaaa 28140 caactgcaaa aagtaggaga agtagatgat aatcgagcgt aatgagaaga aggtagaagt 28200 tagtaccaac atcaaacgct atcaagctgg tatcgcgatc aatgctgaaa ctttcagtat 28260 cttgatcgat ggtatttatg aggacaagat ccttgctgcc tgtcgtgaac ccctgttcaa 28320 tgcggtagat gcacacacag aagccggatg ccgggacaaa ccgattatca tccactcccc 28380 aacggacttg gaaccgtggt attctgtcaa ggatggtggt attgggatgg actttgacat 28440 ggttactcag accttcatga tgctgggatc gtccactaaa cgtgaatcca acgatctgat 28500 cggtgcgaaa ggtattggtt ccaaggcccc gttcaccgtt acggacatgt tcagtgtcat 28560 ctctatcaaa gatggtacta aaactgtgta ctctgttcat aaagaccaag ggatacctga 28620 ggttgtgcct ctccacgagt caaaaaccat agaagaaaat ggtgttgaaa tcaaattcaa 28680 cgttgacccg gcagagactg agaaataccg ccgtgcaatt atcagttgcc tgcgttatgc 28740 taagttccct tacgagatca atgacccatt tgtgacttca tctattcgag accgtaccta 28800 cccggtgcag tatacgttca aagatgaaga atctggttgg atgctggaaa tgtactcggc 28860 ggtatctaac aatgctgata gcgttgtggt tatgggacaa cagccgtaca agtcaaagtt 28920 tctgagcaat aaccctgaat ggcctctgat gatggtgtcc attccgatcg gggattgtga 28980 cgtaaaccca ggacgtgaat ggactatcga gggtaagaat gaccgtggct tcgaagagcg 29040 ccttaagaca ttcgttcaga cggcccttga tcgccgtggt gaagaaattt accatgaact 29100 ccgcaagctt caaaaacttg ctgatgttct ggagtatatg aagcgggttg gcgggtggtt 29160 tgccaccaaa tatggttcaa agtacatcgc ggaactcttc gcagagcaca ctaactcttt 29220 gaatattaaa gagtgcgtga cttataatgg tcatggtgaa aagcggaggg tagataagac 29280 atactcttac accgacatga tgaacggctt ccatcttgta tacaacgacg acaataagct 29340 ggttagaagc aaatgtaatc agttgtttga cgtatctggc aaggcagttt acctgacgga 29400 taatcgaggc gtggcacaaa tgtgcgggaa cccattcttc gcagggatga tccataggct 29460 gtcggatttg gaaaagcgtc cagcatcgaa gtcggataaa aagtatggcg gctatagcct 29520 gtatgaacca gggcatccag tatggatcat tgagcagagt ggagctatta ggaaaacacg 29580 tatctcccgt gcggaatttg atgatatcaa atatgccatg atttattctg gtggtcaggc 29640 gcgtgggact tgtgatcttg gatctacggc gtacctttct aaccgtcatc agccagagac 29700 cttcttgtcg gatcttggta ttgatgataa attgtacatc gtacctttaa atcgggttag 29760 ttggttggat gatgatgttc ggatgatcac acaggacgac ctttataaga ttgcaagttc 29820 aaatctgtta gagtatcatc ttaaccagtt aactaagcgc tcggagtatt cttctcttgt 29880 taaagacttg aaagtcttgg gtgttgagat agttaaagac cctgagtaca agcaaaaggt 29940 taatatggct aacacccttt acaatattaa agggtattat cgagcagaaa aaactgcgga 30000 aagaatcgtt agtggacgga ttcgtattgg taaaggcctg atcaacaagg taaaagaacg 30060 ttacccgtta ctgaagcaca tcccgatgga gcattttaac tccccagagg tggctgagta 30120 tcgtaaattt attgatagca aaggagagaa ataatgagtg atctttttaa atcccgtgca 30180 gatgctcgtg tttgtgctgc aagtcgtggt atgaaggttg tagaccgtgg tgtatcccca 30240 gcggtgctgg cagaggggcg ttggatggtt gtccccaaag acagtattgg tgcttccccg 30300 gaaaagacga tttccttcga tatggaaact taccctgcgc caactgcctc tatgttcttt 30360 gcgagtcggg gagaggcccg agcattctct aagactgtac agaatgcgaa gattatcgat 30420 catgcaaaga caacagcagg acatgacaaa gaggagggag ttgtcaagga ccttggcaag 30480 cgtggtaagc gctgggaagt ggtgttcgta gtttctgatg tagaagtgag cgttactgtt 30540 cctcagcttc cagaacctac acctgtgcct attaagattt cggttgttga tgacacgaaa 30600 gctgatccca ttgtcatcat gacaccaggc aacgtttcca tcacacttcc agatggaacc 30660 attcatactc tgggcagtaa cagcgaaatc tttaacgacg tcggtatgtt gctgttaaac 30720 aacaagatcg acgaagcagt agcgcttatt gaagcgggga tcgctgcaaa agctgaagtg 30780 gcaatcgacc ttggaccgga tatgaagctg ctagacggaa ttctgtactg gcacggtatc 30840 aaacaagaaa gcggtattgc tcgccgtatt gtttccgata tcgagaccgg gaagttcgat 30900 aaccgttatg tcgagttcat gcggaagctg atgctcaatc cttcttacaa atcggttgaa 30960 atgctgtacg acttcctgga gcataacaag ttcgagattc tggagaatgg caacatcttg 31020 gcctacaagg gtcttaaacg cactgagaat ggtcctcgtg actggttcac aggcttggtc 31080 cctaactggg ctaacaccac agtcactatg ccaagaaaca tggttgaaga tgacccaacc 31140 aaagcttgta gccagggttt acatatcgcc tccaaggaat atgcccgtga ttatggtaat 31200 gtggttgagg tatctgttga cccggcagac attgttagcg taccatataa ctacaataac 31260 aagaaatgcc gctgctgccg ctatgaagta ttgacaggaa aagaaaagcc agcaggtgct 31320 cctgatgtta ttgttgtggg tgtaaggggt gctatcctgg acgaaattta tctcgataag 31380 gaggattaat gtccttagtc cacggacagg gcattaatga tgccccttat cccacaaccc 31440 ggtacactct tgttggtggt aagcgcacac aggcgtggag gtgcccgtac tacaccctgt 31500 ggcgtaaaat gttggaaaga tgttactcag acaaagccct gaataaaaaa ccgacctact 31560 ccggggttgt tgtggaagag gcgtggaaaa cgttctctaa tttcagagag tgggttgaat 31620 gtcaagatca acacgttgct tggctcgagg aaagtgggaa aagaatagtt gacaaggtgt 31680 ataattttaa tttagataag gacattcttg tacctgggtc aaaaatttac agttggaata 31740 catctgtgct tgtaccttct tatctgaata aattttttct gttgcgggat tcagctaggg 31800 gggatttccc cattggggtt tcttggcatt ctgtggttaa aaaatttcaa tcaagaagaa 31860 gaggccagca tctggggtat tttgatgacc cgttcaaagc acatcaagcg tggcaaaatg 31920 ctaagatctt ggatataata gacattcatg acagatattc gcacagtggt gtttgcgacc 31980 acagagtctc cgaaagattg cttatgatag taaaaaacat aaggcgagac ttgcaatacg 32040 gtatcgagac aaaaaattta ttaggagggt aacttgagag aggattttgg agtgggaacg 32100 gaagaggcct taggtgctat cattgaaggc aaaaacgttt tcattacggg acctggtggt 32160 agtggcaaga gccatctgat caaaacaatc caatccctgt atccaagttc aacattaaca 32220 gtggccccga caggggtcgc ttcacttaat gttgatggaa tgacaactca tcgagctttc 32280 gggttatcaa tggggatagc cacagaggat gatggtaaga cagtaaaaac taaacctaaa 32340 aaacttttaa aaagcaaatc tcttgagcgt atcattattg atgaaatatc tatggtgcga 32400 gccgataaat tgtgggaaat ggatcagaaa ctgcgtgttg cgagaaggga gcctaagaaa 32460 gctttcggtg gtcttcaggt catcatgttt ggtgatttct ttcagaaccc tcccgttctg 32520 acagagtctg aagaaaacgc ttactttgaa ctccacagca cagaattatc ttgtttctca 32580 gacacttggg gagagataag tccataccct gtgcttcttg acaagattta tcgtcaaaac 32640 agcgtgcatt tttcatcgct attgaatcat atgaggaaag gcgagcgtat tgatgaaata 32700 gttaaattcc tcaacaatca gtgctattca aagggtgcag cactgaatgc gattaccctg 32760 acttcaacta acgccgcagc tgaacgtatc aacaaaaagc attacgacca gataccgggt 32820 gaagaggtta tttacaaagc ctccaaaaca ggagattttg cccagcggcc agttgctgag 32880 agtctacacc tcaaggtagg gactcgtgtc atgatcaccg ttaatgatca gaatccagat 32940 gaagacggtc ctaaatttgt aaacggaaca cggggtatta tcaaggccct aaggaagttt 33000 tcggtagatg tagaactgga agacggcaag gttgtagaga tcgaaaagaa tgtctgggaa 33060 aatgttgaat acttcccaag aaaggttatc aagaatggta agactgaaga ggaattggaa 33120 aagattgttg ttggaacata cacaaactta cccattcgcc ttggttatgc agtgaccatt 33180 cacaaagctc aaggcttgac tttgccagag gttaatatag actttggtta tggagctttt 33240 gctcctggga tggcctatgt tgcctttagc agggccactt ctacaaaagg tttaagattg 33300 ttgcgtccgg ttaaagaacg tgatattatc gtagaccaaa gaattgttaa attctacaaa 33360 gacacattcc caggaaaatt ttaggagaaa ataatggcat catattctcg tctggagctg 33420 gcagacaagt tccgcaaaga acttgaagta tggaatcaat ggcaggttcc tcgctctgaa 33480 aaagctatgg acactaccca catccaaatg gcctctcttg acgagatgat gtctgcttat 33540 gggtatgtcc ctcgtcgtct ttctaacttc ccagaagtta aagatggtcg ctttggctac 33600 cagcttgcat tccctcgatg taaaaagatt tgtcgcccat tctttatctc gttacaggat 33660 gcagttagca tccataatgg caatgggtac aaggggaatc cattccgtag gttgggggat 33720 cgcatgagtt ttgctctaca gaaccgtatt gttgagcagg tggcggttca gagggacaag 33780 tctttggaag gtggtatcaa atcaactaag aagtggatta agttctatga ggagaacaaa 33840 aatgcaggtt gaagacttca ctgacctgag taaggtaaca acagaaaagc taatgaaact 33900 ccgtgatatc gctcaagatt atcacgatga gatgcagcaa gctgaactgg aagcgtggga 33960 aagactccaa gatataattc atgaaattgt caagagggcg aagaatgttc aaacgtctaa 34020 ttaactggct ctttgccaaa gaggatgaaa ccacagaaaa tgaagttcgg gtatttgact 34080 tcacagaaca aggtcctgga catgatatcg ctatacgagt catcaatgat ggtgaatacg 34140 cagaggcagt ggttgccctg aaacttgcgg atctgccgcc tgcggttggt gacttcatcg 34200 tcgtagtttt agatggtgtc cacaatactt ttgtggtaga aacttcagaa ggtgtgagcc 34260 tgactgttac taaattgacc ctaactcgtt atgaaggcgc agaagatgaa acatcgtgaa 34320 aatatttgta agcttattga tgatttgaaa cgcatcgcaa gtcaagcaac accaggtaag 34380 tggtggatag attcacatgg tcatgctatg gttgcatttt caacggaaga tgctggcatg 34440 gaaacagtgt ttgtgacaga cggaaatatg ggtccggttg tgcgccatga gaacacaggt 34500 aatctttcgg cttggcgcaa tgatatggat gcaacataca ttgcgactgc ctgccctcag 34560 aatgtgctgg cagttctgga atatctaagt tctggtgcta acgcgtggaa taccataagc 34620 acttatatgg aaactcgcct gcatggtgat gcagccgctt tacgtaatga tgtaagccgg 34680 aagttgtttg atgacggttg tcatagtgca gcagtccatg caattcagtt tatcgaggca 34740 ctcattgacc agaatattga attaaaggcc gaactggagt ctaaatgatc aaagattgtt 34800 ttgggaatga ggcgagagtt ggcgacaaga tcgccttctc tcaaggcaat gctggagcaa 34860 aaaagtggga attcggggag attacccgga taaccgataa gtgcatatat tttcatggtc 34920 gcgccggggg aatgttccgt gactggcgtg atgataccga gcttcgccgt ggagaaggcg 34980 cgttcgtaat taatttagag gcgagaggac ttaatgagta aagccgcact tcctgtagag 35040 atcgaattca gttatgacca ccctactgcg ggtgtcgtca ccgtcgaagc actttattct 35100 gtgatggaag gcgaccgtaa cagtcgtgaa agcgatgtag attacaacgg tttccaagat 35160 ttggagtatt atgctgtatt ctctggaggc aaacagatct acgttgacat tccagatgat 35220 gtcctatacc atcatttacg cgagtatatt cgcaatcttg aaattgtagg ttgcttccag 35280 gaagaggagg agttttaatg aaacacgaag ttaaagtcgt cgaattcgaa ttcaataacc 35340 acagtggtcc aaattacgtg gctaaagtgt tggcagaaca tcttgatgaa ggatatacta 35400 tcgcagggca atctgaaagc gctagatatc tgacctacac cctagttaaa attattccaa 35460 tttccatgac gggtacggta acaaatgccg atcaccaagg ggtcagtttc cactaaggga 35520 ggccgtttga agaagaaagt gatcattctt tatgattaca cttcggtcat ggcccgtcct 35580 tggttagagg ctggctatga agtttggact tttgatggtc aacattcacc aggagtcacc 35640 cgcgagggtg accttgttaa agtcgggatg tggttcttcc acgacaagac cgttcaacaa 35700 gctcaagaga tcaaagaaat ggttggtgac aatgttcaca tcgtctttgg tttcccggaa 35760 tgtactcacc tgaccaatgc aggttcacgt cattgggcta agaaaagagc agcaaaccct 35820 aacttccaga aagaagcaat ggaactttgc ctattggtag agaaggttgg agatttatat 35880 aatgttccgt gggcctttga aaaccctgtc ggtgttctct cttcaatgta tcgaaaacct 35940 gattacatgt ttgatcctaa ggattacggc gggtatctcc caaccactga tatacaccca 36000 ctatatccgc acgtataccc tcctcaggac gcgtataaca agaagacgtg catttggatg 36060 ggcaatggcg caaaacagcc tgacaagctt cctgtgaagg aattgtacaa ggacaatcca 36120 ggctggaaga agtgtggtgg caaatccacc aagactaaaa atattcgtag ttgtacacct 36180 cgcggttttg cggaggcgtt ttaccagaaa aataaatgag agggataatg ggaaatggac 36240 cggattgggc ggcgtatcgc aaaggtggca atgaaaaccc aagagcaggt tttggaagta 36300 atcgcggagg caagttgagt tatagtaaca atcgagcaga agagaccctg gaatcagtgc 36360 tgtctggcac ccgcatcatg gctgttcccg aaatgagtct ctctcttgaa gcagcacagt 36420 attttaagat ccgttctgcg gtatccccgg cggatggtat caccccggta gcaacatact 36480 tgccctatta tgataagtat gggaaactaa cgggattcaa gaaacgtgat tggacgttac 36540 agaaggaaaa gacaggacac ttttcaactg ttggtgctgt gaaggcatca tctcagttct 36600 tcgggcagca tgaagcctct atgggtgttg gtcgtaagca gatcaatatc gtggaaggtg 36660 aaggtgacgt atgcgccgca tggcaggcag cgtatgagat ggttaaggct atgtccacca 36720 gtccaaaggc cagtaaaggc gttaaagact gggcggatag catcttaaaa ggtatccgtc 36780 atattcagaa cgacgaggac attggaggtc ttccgacact accctatgtt ggattaaact 36840 gtggtactgc aaacgctgtt gatactttcg caaacaacga gaagttcatt cgcagttatg 36900 agaaggtagt cttgggcttt gataacgacg aagccacagc attagaaaaa gaaaagaaaa 36960 taaagaaagg taaagaagca accgacgatg tcgctagctt cctgctgtca gaaaacattt 37020 acgttgtgcg atatcctaac gagcgtaatg acccggatgg ctttaaagac attcgtgaca 37080 tgtatgatgc aggtaaggta cgcgagcttt atgcaatgtt taccaaagca gacgatcgct 37140 atgtccctga taagcttatc ggtcttaagg atattaccat tgagaatctt cgcaagaaga 37200 aaaaagatgg tgttccatta ccagggcttc ccggcctata taacctgacc cgtggtcccc 37260 gtactggtga gctttggaca ttgacaggac cgtctggtgg tggtaagtct acaatctctc 37320 gtaagattga atacgcgatc attgattatc ttcgtgatat gtcaattccc cgcctagatg 37380 gctggaccga gagtgagaaa gtagccatca tccgtctgga agaggatgaa gaagagtctg 37440 taaacagctt gtatgctgaa gagctgaagg tggaccctaa ggcatttgtt gctgacccgg 37500 agcagttctt aaccgaagag caacaccttg agattcacca acgctggatt ctggaagata 37560 agattaagat ctttgatcac ttcggttcta tcccgacaga ccagcttatt cagaaactta 37620 agcagatggt gttccttgat ggttgtaaat ggatcatcct cgatcacctg tcaatggtaa 37680 tctctggtct taagtccgac aacgaacgtc gagaccttga taacatcatg accgagctgg 37740 cagctttctg taagaagtac gatgttttca tcttatcaat cagccacatg aagcgtaaag 37800 aacttcagct tccgaaagat aaagatggga atctattacc gttctggtat ccggtccgta 37860 aagaagacct gcgcggttct gcggcccttg aacaactctc atgggtggtt ctgggtgttg 37920 aaccagaaga gcttcctgac cgctcccgtg gacgtgtacg tatcgtggtg ctgaagaacc 37980 gcccacacaa aaaactgggt atcgctgata caatggttat ggatgacaac ggacagttct 38040 ccgatgcttc cggttgggaa tgggaagatg gaatgttcaa gcttaatggt gaagttatgc 38100 ttcgtcctca gagcctgatc catcaactat ccctggaaac tccggttgga aaggtcaatg 38160 tcccggcacc tgagtataag ccaaccatcg atcttgacag gacccccgtt cctactcttg 38220 gtcctgacga tgatacgcct ttcgccccga taggattgca atacgcaaaa catgcaattt 38280 atgtaattta ataccaactg agaggtgggc gacggtacag tctagcccac cttgaatagg 38340 aggaatcatt aaaggtctgt ttatactgga taacgaggcc gatggcctgt tagacgaagt 38400 aacgaagtac cattgtactt tgctgaaaga atttggggtc aacaactgga atctgttttt 38460 agaccccgca cacccagaat atgaaagcgc tgtagccttt gccaggagca agaaggatgt 38520 taaccttaca attcgttcat acgacgagct ggaaagcttc ctgaagacgt gtagggccat 38580 tgcgtgtcac aacctgtttg gctatgacct gcgtctgtgg aagaagttat cgggcattga 38640 atatgatatg ttcaaagacc cgaagtgcat ggggacgatt ggggatacac aggtaaatct 38700 ctacgacact ctctctatga gccgtgtgct ttatcctgac cgtccattgc ccaacggttg 38760 ccctgactct gttcttaacc cggtaaccgg gaagcgagat cgtgtaggtc ctcatggcct 38820 gttggcctgg ggctaccgtg tagcaaacaa gaaagttcag atcgatgact ggcgtaacca 38880 acccttgtgg gaatacgtta atcgtgtctg ggaagacgtt ttaatcaacg agttagtatg 38940 gcaatccctg atcgatgaat ctacaggtgc tcgctggcct gatgacaagc agttcatgta 39000 caaagataaa ccggaaggga tgcggcagat caactggaag aacgcgctac gccgccgtat 39060 gttgactgat tacctgatga ttgagcaaga aattcagggt gttccattca ataagcatga 39120 agctgaaaag ctgagagacc gtattgatgt aatgatgaaa gagattgagg aagaagtaga 39180 acctcaactc ccgctcaaag agatgacgaa gtctcaacag ccaaaattcc ctgctaatcc 39240 ttttgatggt gcaggaagaa tttcccatca cgggtggaat tggttagaat acaagctggg 39300 atatccagtt aatcgtgaag cgctggaatt caaaggtcca ccgaagacgg cgtttaaagg 39360 taacggtgat gtaagtgcag caggggaaag atactgtatc cagaatggtg ttgaagaccc 39420 ggcagcgatg ccagacttca ttagaagcca gataaagaaa gagaataccc ttgtcccatt 39480 gccaccagac ctaatggaaa aggcaattgc cgatcttcgt gctggaaaga tgccagacct 39540 gatggttccg atgaagatct cgaaccagga cgacatcaag aagtacctga tccgcgatgc 39600 gggatggaaa ccaacgctct ggcgtgttaa agatgtgacg aaagaccagt tcaaaaagac 39660 ccgcgatgat gcggaggttg atggtctggt gcgtaagtac atcgaagaac ttggagagtc 39720 cgagtataaa tctctgattc ttgagcactt aaataatagt gacgcaaagt tcaatatctc 39780 ggaaaacaag ttcgaccatc gtcatggttc tgatcgtgtt tacgaggaga tcttcaagaa 39840 gttcagacgc aaagctcgtc aactgccgac ttcaccacag ttgaaggata actttggcaa 39900 gctatgtccc aaccttgaag ttatcgacgt tcacttggct aaacagattg ttaagtggct 39960 gtcattacgt aaccgtcgtt ctgttctcga cccgattgac gaggacaaaa acgacacagg 40020 gctgttgaat caccctcgcc tggcgattga tggaaaactt ccagctcgtt tctccggcat 40080 caccaatacc gggcgctgta agcacaccat ctgtgcaaac atgcctaaac cagatcctaa 40140 ggtgttgttg ggtaaagaga tgcgtggtct ctggggtgtg accgatgaat attaccaggt 40200 tggtatcgat ggttctaacc tcgaaggcat gatcgcagca tggggcgcat atcagttcga 40260 tggtggtgaa tacctccgta ttatggaaag tggagatgcc cacgcacgaa acgccgaggc 40320 atataccaaa gcctctggta cgttggtaac tcgtaacggt ggtaaagggg taacctacgg 40380 ttaattgata gcccccttat gaagtaattt ataaggtgca tccattgaat tgctgggaaa 40440 tctgaccgag taatgtcgaa gataatcagc aggtaagcaa aggcttccct cttaagaaac 40500 caagaggagg agatatggga acattttgtt gtaggatttg tggtgttgta gagttaaaaa 40560 ctggaagaaa tcaaaaagtt tgtctgtcag aagattgtca gagagaagtt tccaggctca 40620 gaactcaaga gtacagacgc agaaaggcca agaaggaagg caggcttgat agggttgata 40680 taggaagagg tggtggtcaa ccaagcggaa aagactctaa gcattacaag actggtatcg 40740 cacagtttca caagctggcc ccagtaatcc gaaaagagcg gagatattgc aatagatgca 40800 ataaggactt gctcgaagtg gggaaagatg aatggtgtgt tcatcatata gaccacgaca 40860 gaaccaacaa cgaggtgagt aactttgagc tattgtgcaa aagatgccac cagatagaac 40920 ataattgttg ggaagccttt gaaacttcaa cgactatccg gtaacggagt agggccaagc 40980 ggcccgaagc ggtggacacc ccaagtgggt gaagatatag tctgctctgc atggaaacat 41040 gcagcagttc ataagagaac gggcatggtg gtagcgtccc atgtcgaaca ttaggatcat 41100 gtatggtgct caggcagcta agattgcagc aatgcttcac atttcccttg acaaggcaca 41160 ggcggtaatc gatgctttct gggatagtaa ctttggtttg aaaggtcgta aagaatggct 41220 tgaaaacttc tgggaagcaa ctgggaaacg ttatatccct ggcctcgatg gtcgtaagat 41280 ttggacccgt tctaagcact ctcttctgaa tgctttccag caaaacggtg gtgcatctct 41340 attcgatctg gtgggtatcc ttcttcattg ggaactgatc aaacgtggct ggtatgatga 41400 tgacgttcgt cgcctgattt actaccataa gtaacattgt ggctttgtga ggtaactcac 41460 atcgaataac tcctttaatt gtcggggagg ctaagtcgaa agatatgcta atccgcagcg 41520 aagcttgtca gtaacgctct taggcacaca gtttttacgc gaataagggt taatagtagc 41580 gtgtgcaaac gagtaacccc gaaagacccg aagacaagaa cgttcagagg ccagccgaga 41640 ggcgtaggtg accaagtggc accgaaatgg ggagcatccc gaaagggatg gtgagatggt 41700 ccgatcctat gtgaaaacgt atggcaacac gtcatggtgt gggcgagatt aacgacctcg 41760 ctaaactttt ggatgaatac cagctccagg ttcctaagaa atacctgaag aagtgggagt 41820 ttgataccct ggaagaggca acagctttcg ttaaagaatg ggaagcaaaa ggccgggtat 41880 ttgatgggca tgaatggaga aaggctgtca aagatgaaaa tggtgataaa gtcaaagatg 41940 cggaaggaaa tacagtctac gagggtattt tcggagacga tgggaaaatc cacatccagt 42000 attgccctgt tggtgaaatg gttgtaaaat gtgtagagaa ggccgctcgt atcatgggca 42060 gtcctgtaca tatcacaggg gcatacctga ctggtcgtaa ttggagcgat tgccattaac 42120 gataggggct tcggcccctt ttttcatagg agaaatcatg tttccgaaca aacctaaaga 42180 agcaacccat tactttatgt atccaggaca tcctacccct ggcggcaatt gggcgtacta 42240 tgtcagcttt ttcaggaaag ttgcaggtga gtggatggtg tacactaccg ataccgacaa 42300 tgagtacccc ggctggtcat tggcttctag acgctataag aataaaagct tcgagaccat 42360 gattgaatat ttgcaagaaa tttaaaaata gtgttgacag ccgtttcgaa tagcattaaa 42420 gtgtatcaca tgaagacgag agacctcgct tcaaaataac ttcacaaaca ggagaacgaa 42480 atgaccgcaa aatatgaaac cgtaccttac gctgacttcg taaaagctct gaaagctcag 42540 ttcgctgtca tgcaagcgct gggtgcgctt tacacggtcg atgtaccgaa agatgaactg 42600 tacgacttgt acctcgactc tttcccggaa ggcaccaatc tgatgtataa agagcgccgt 42660 gaatatgact gtaactgctg caagagctac atccgtactc tgggccgagt agtcgcgatt 42720 cacaacggca agctggtctc tatttgggac gttaaagttg gtggttacta ccaagttgtt 42780 gccgatgcga tgaaagcgcg tgttgaaagc gccgagatcc gcgatcgctt cttccacttc 42840 gaaggccgcg ttggtactga gagcaacgta gctctgctgg aaaatgggaa aaccaaaacc 42900 tggacccact tccatcaggc cctgcctcgc gaactggtta aacgtggtga agatatccct 42960 tctgccctgg gtgagtaccg tgacaacgca actgtgctgg cacgttctct gaaagatatc 43020 gatatggact ctgccgaaac ggtaatggac ctgatcaacc aaggctctct gtaccgtggt 43080 gatgagaaaa agcacattgt tgctgccttt attaaggcga aacgtgcata cgacaaaacg 43140 ccggaagatc agcgaatgaa cttctgctgg aaacaaagtg aaacgctggg taaactgggc 43200 cgcttccgta atgatgtcat cggtacactg atgagcgatc tggcagaagg tattgatctt 43260 gaagccgcag tgaagtcctt tgaagacaaa gtctcaggga ccaactacaa gcgtactaca 43320 gctctggtaa ctccgggcat gatcaaggca gcacaagaga aggttgaagc cctcggcttg 43380 actgaatctc tggcacgtcg ctttgcggtg acctctgacc tgacgatcaa caacgtgttg 43440 tttgctgacc gttctgcaaa ggcccagatg aacgtattcg agcaactggc agcgtcaacc 43500 aaaaacgcgc cgaagtcact gtcgaaagta gaagagatca gcattgagga tttcatcaac 43560 aacgttctgc cgaaagcgga cactatcgaa gcgctggttg aaggtcgtct gacaccgaac 43620 ctgatgagcc tgattgcccc ggcaaacgca ggtgctccta acctgttcaa atgggataac 43680 ggcttctcct ggtcgtataa tggcgaagta actgactcca tcaaggagcg tgtgaaagcc 43740 gctggcggta gcgtgactgg tgacctgcgt gtttcgttgt cctggtacaa cagtgatgac 43800 ctcgacctgc acgtattcga gcctggtggc ggtcaaattt acttcggtaa caaacgtggt 43860 cgctcaacgg gtacgctgga tgtggatatg aatgcctatg gcaagtcaga cgcacaccat 43920 ccggttgaga acgttacgtg ggaaaatgag cgtaatatca cggaaggtgt ttacaaggtt 43980 gttgttaaca actataataa gcgcatgact gatcgcgttg gcttcgaagt acagatggaa 44040 tacaaaggcc aagtgttcaa ctttgcatac ccgcaagctt tgggtaatag caagagccag 44100 accgttgtaa cctttaagta ttctcgtgcg aaaggtgttg aaattgtaga cagcatcggg 44160 catactaagc aatctaaaga agtatggggc gtctctaccg agaccttcca gaaagtttct 44220 ctggtgctga attctcctaa cttctgggat ggtcagacca aaggtaacaa acactacttc 44280 tttatgctgg aaggttgcat taaccctgac gatactcgtg gcttctacaa tgagtatctg 44340 cgtgacgagc tgcatgagca tcgtaaagtg ttcgaagtgt tgggttccaa gctcaaagct 44400 gaacactcca ctgatcaaat gagcggcctg ggcttctcgt ctacccagcg taacgagttg 44460 gttgtgaagg ttactggttc tttcaaccgc accctgaaga ttaaattctg atgaaaacgg 44520 ggttgcaacc aaccccggta actgatagac tcgttgcatg tctggagggg ttcgctcctc 44580 cagaaaatcc ttaccaaagg atatgcaatg agttcgggtg tgcgtacata actgcaaaga 44640 aaatgttgca ctcctttacg taccgggcaa ctgaacaaca attggctgcg attcttgaag 44700 aacgcagcat actgaaaaac taaaagagga gaacaaaaat atgtcaatca tcaatactac 44760 catcgcaaat accgctaccc tgttcgaact ggctacccgt aaaaaactgc gttttgcaag 44820 cccgaaaggt ctactgacca cagaagatct gtgggatctg ccgatgactg gtaataccag 44880 cctggatacg gtttccaaac tggctaaccg tgatgtgaaa gcatctgctg aagaaagttt 44940 cgttgtcgag gccagtgctg taaatggcga agcaaacctg aagctggata tcctgaagta 45000 catcatctcg gtgcgtaaag cggagatcgc ggatcgccag gcagcgaaag agaaggttga 45060 gcgtaagcgt aaacttctgg acctgctggc agagaaggat aacgagaaag atgcagcgat 45120 gtctcgtgaa gagatcctga aagagctgga atctctgtaa tctgcccgcc aaggcccttc 45180 ggggcctttt tgtgttggag gataaatgaa agtaactggc aaacaaacta ttgtacagaa 45240 tgtggaagta gatatctctg atgaagagat catgaatatt gtcaaggcac aaacaccaga 45300 ctacctcgca gatgtcctca ccaaaaaact gctgagggac ttcatctata gattaccagc 45360 agattttact ggtgagcggg ccgtgtggga aacacgtaaa agaggatatg aaccgtttct 45420 tgtacttgtc catgtagacg cctggtggga ctaccacaac aatgttggtg tggatgaaga 45480 agtcagaccg ctcaccgaag aagaaacggc aaaatataat atgatttgcg gtttgcggga 45540 ctacattaag gagctgcaaa aataattcaa aagcctcttg acttcatggt tgaggggctt 45600 tattgttatg gaagctaaat aacctggagg gtgtatgtta gaggcaatca attatttctt 45660 tttagttctg gcagcagtgg cctgtgtttc ttgtgccttc ggcgctgtct tttcaaaaga 45720 tgaaacacac cgcacggtgt acgtaggttg tgcagtcatc aacgctgctt ttacggtgca 45780 tctctggagt atcgccctat gaagctttca cattttattt atgcagtgtt aggccttatg 45840 gccctgacca tgctgacaac gttggggctt tcatttacag cagaccatga gcaacaaaca 45900 aaagaaattt tgggagcagg tttcggtatg tttatgcttg aattcttcct gcttcttttg 45960 ggcggtgtga ttgtcgatac ttccggctgg taaggagaaa taaatgcgtg gattcatgcc 46020 ttgggtgcgt ccgttggtta ttgtgattgt tgttgcagtt gtcgcctaca tatcgcttga 46080 catcgcagat aacgtgaccc ataattgcaa gcctaacggt gagcaacgcc ttgctaactc 46140 ggttgatggt gttatcgttg agaacaaact gatctgcgac ggtggtcgag tgaagtggtc 46200 tcgctactaa attctgacta aataatctca agaggagatt caaatgaaaa agattatcct 46260 agccgccctg ctcgcgcttt cttgctctgc acaagcaaca gagttttatc ctgaagcaaa 46320 cccgaatgat attaacgagt ccgttgatag tgaactggca aagtccctac tgaaacgcga 46380 cacccttgaa ttgaaaatta aaatcgcaga gcttgaagtg gaacttgcca aaatgaagaa 46440 gactcaagtt ctatacagca ttgcccttga atcaatggag aaaaacaaat gacgattact 46500 cgcggcctta tcttcggaaa gtttgcaccg ctgaccaacg gacatattga attcattcgc 46560 caggcggctt ctcaggttag tgctctgtat ctgttcctgt cctatgacca gaaattcgtt 46620 gacgcacaac cagagtggat tcgtcctaag ctgggacttg ctgatcgtta tcgtgacctg 46680 ctggatgtca ttgccgacga gggacttgac aacgtgaagg tagactacgt tgatgagtcg 46740 aatatcccag gataccctga aggcagtgct gcctatgcaa aactgatccg tgaaaagcaa 46800 ccgttcgtta agtacgattt tgctttctct tctgagccgg agtatgagtc ttacttcagt 46860 gagttcttcc ctgaagcgaa gcatgtagtt atcgacgcag aacgtaaagc tgttcctatc 46920 tcagccacga tgatccgtaa tgatccgtac aacaacttct acaacctggc gtggcctgca 46980 cgtaaacgct tcatgaagaa ggttgccatc attggtgttg agagtacggg caagacaacc 47040 ctgacaaaac atctggcgca taccttcggt gctggttgga ttcctgagat cgggaggctt 47100 atctgtgagc gtgaatacca ctccagtgag ttagcaatgt ctcgtggaga ctatcttcgt 47160 atcgcaatgg agcatcgcct gaaggaaatg gagttagctg gttggggtgg ttgtggggtt 47220 atgttctctg acaccacaaa cctgatcact catttctctg gtatttgtgc agacaagatc 47280 gactactccg atcttctgtt ccgcacactg agccgtgaag agagctacaa cttctacgac 47340 ctattcctgt tcctaacacc agaggtccct tgggttgctg atcctcttcg tttacaggat 47400 acaccagaaa aacgtaaaga aacacattct ttgcttgaca caatgatcag agcatcttac 47460 gatacaagca aggtggtggt tatctccggc agtgattacg acgaacgtac tcagaaagcc 47520 gaagaagctg tccgtaaatt gctgaatatc aaaggagaaa aagatgaacg taactaattc 47580 aagcatgaag caggcttttg gtgttctgaa gattattttg gaaaaggcac ctgaattggc 47640 ggaaggtctt caggcttatg ccaactgtcg tgagcaaggg ttctccatca tgaagttgga 47700 ctgctccggt ggagaagata attgtcgcca agtgtcattc tcagaatgtc gtaacagtga 47760 tcagatcact gtgtactggg gtgggactcg tgacttcaat ttccaaacta acatcccaac 47820 tgatgatacc tatttcaatc gccgtaaatt cttcggctat gaggagtacg aagaggtagc 47880 agactggatt attgcatact tgaagggtga taacgatgga tcaaactaag ctggaaattc 47940 tccacttctt agagaagtct ttagaggaaa agcagggatg gacgtaccac aaagaggtgg 48000 ctgatagatt tggtgagcct gccactacag aggctctctc ttctcttatc gggcatggta 48060 aagtggtggc ttgtggctgc gggtgttccg gtatgatgat cacccctgtg ggacttgagg 48120 atattcgtcc accaaaacgt atcatggtgt ggaaaacaga atccgggaag gttgtcaggc 48180 tgacacacat gtctgatgac catctgcgaa atgccatcat ttggttgcta acagactcca 48240 accttacgga agagtacgag ggttattgga tcacgcaatg gttagtggct atgtctcgtg 48300 agctgcacag ccgtgtatct gtataatggc taaagttctc aacttttacc acatcggtaa 48360 agtgatccct gaaaatgctg agtacatggg gcgagccatg cccaatcttg gtttgaaaca 48420 atctaagttt gctaataagt tcaaattgaa taaagatggt tctaaccgag ccgaagttat 48480 tgagcaatac cgggtgtggt tgtggcaaca aatccgtaca ggtaaaatta ctattcaaga 48540 tctgcttgac ttggatggta aagaccttgt atgcttctgt aaacagccga acaaagaggt 48600 ggcatgtcat tgtgatgtga tacttgcggc aatcgaatgg gctaaacaaa ggagtcaaaa 48660 tgtctaaaga atttatggac tggtttgata aaaacgcacc agcgcatctt tatccagatg 48720 cagaggagcg tgaaatcctc cagttaatgt gttggttggc atggagagat gggatcaggt 48780 ctgtcttacc agttgtaatg gagggttaaa aatggctatt catgcaaaaa gtaatggtct 48840 actgatcggt ggtaagatca tcgaggagac actgacaggc tgggttttcc aggcaatgga 48900 taacaaaggt actaattttg tgttcaagtc agatgagaag aaccaagttt ttgacggacc 48960 gaatgctgtt ggcgaagcaa tggcttggca aactaaagtt cggtcagaaa tgaaaaataa 49020 aaagaaaaag gggcgcaaaa atggctaaag atacatggga agtatttcat gatgacgatg 49080 aaataaaggt cattgtctca ggctctcttg aggtaggttc cgggtggcga tcttacagcg 49140 acgtgtgttc agagattaat agtattgaag atgcaaatct tatcgcagca gcaccagaac 49200 tgcttgacgc agtgttggat ctgaagtata agttatacgg taacggcgcg gcgaatccta 49260 aaatcgaagc acttcttaaa cgattaacag gagaataacc atgaatacaa atctgtacat 49320 taagacagca tggaccgact tttatggctg gtcaaaactt gaataccttt ggctcctcat 49380 ctgctcggca tcgatcgcca ttgtctcctt gactatggac ggtgggttag tagagttcat 49440 ctcttctgtc accgggatca tcggggctat cctggtggca aaaggtaagc tctccagtta 49500 ttactggggc tttgtggcaa cggtgctgta tgcatatatc tccttcacgt acaagttgta 49560 cggtgagacg attatgtaca ccctgttgtt cacccccatg caggtcattg gtggggtaat 49620 ctgggcacgt aagttaaccc tctctgcgga tggtgaacgt gcggatgtca tcaagaagta 49680 cctgaccaca aaacagcgct ggattgttgg tatcgggaca ttggtgacga tcggattata 49740 cgccgagttc gttagcctgc tgaaagggag tatgccgggt ctcgattctg ccacagcaat 49800 cctgtcggtt ctggcaacct acctgatgat ggttcgttat gcagaacaat ggctgatttg 49860 gctactggtt aacactgttg caattgttat gtgggtgcaa gctacgattc atcatcaagg 49920 agctggttct gcgattttgg ctatgtgggt cacattctgg ctcaattctc tttatggttg 49980 gtataagtgg agaaagaatg gctagaaaac tatgtacggg gtgggcgagt gattcaacgc 50040 tttacggaag ttgtagacgg tatactggaa gacatttcaa atttacgtga aacaaccaat 50100 tttggagggg gtaatatatg attggattct gggaatggtt tacaatgaat cacaattggg 50160 tgtctagcct gatcccgctt gctatgtttt cctacatagg atggttattg tcgggagggc 50220 ttacttggaa gggaaaagtg gcctcctatg tgttttcagc cgtaatgttt ggggtaatgt 50280 tctgggtagt gacttactta ggcggttatg gaatgtataa gcgccattat actacttgcg 50340 caaagccaga ggctgtggca tcattctatg tgtttgatgc aaagaaagat cgctgttata 50400 aacctgttgt tggatttgca cctgttgatg ataatcaggt aaagactctg acaccgaaac 50460 aaatggagac tggagaatgg ctttaactcg tgaagaacgc acatgtgcca agtttgtcga 50520 gatgtatgaa gcaagcttag gggacaatcc taatctggaa gaacagttag ttctctcata 50580 tttcaagaaa aatgtagatg acctaccagt ggacttcgcc gacccaccaa gtttccacaa 50640 agcattccgg caggttgaca tctgccgtaa aggttatcaa gacatggtga tttggtctct 50700 gatgtctggt ggcgaattaa atacaatctg gaaagttttg gaagaatttt atgctaattg 50760 atgaacttgg tgttcgtagc cttgtcccag atgcttgggc agaggcctat ggtaagccac 50820 aagctgatcc tcattctgtt ttcgcagagc tgcttggtgt aacacgacag caagcgaagg 50880 tagtcggtta tgagtatatg tactctgaag agaccgaaca tgttcgggcg atcaaactgt 50940 ggcacctatc gggaaaagaa actcgatatg tttaccggaa gcttgctaac ctcttgttgg 51000 agaatggggt tactgttcct ccgctgagag aaattcttga agaggtagac cggaatgaat 51060 aaaatccgaa aatttttcaa atggttattg gggttattca gtacaccaac ggtcgtatct 51120 atagggaagg gaaacagcac ttttgttagc caaacaacca aggtgaccac aatatcttct 51180 gaagagctta atgagacgct caacgaggcc cttcgtcaag caagacaaaa caatgagcgt 51240 agattgaaaa tgtcaccccc aacgccacct tcaccgccta aaaggcgtgt ggtcgtggag 51300 gatggcggtt atcgccggag aaatgatgat gcggcgatca tcaatacaac cacgattagt 51360 gatacgtata cccatcatac gccaagtcac tcgtcaagta gtcatgactc gtattcctcc 51420 tgtgattcga gttcatcatt ttcaggtagt tgtgattaag gagataaaat gaaaattggt 51480 ttcttaggtc ttttggcgtt ggtatttatc acgcttaaac tgtgcggcgt gatcgcctgg 51540 tcgtggtggc ttgttttact accgctctac ttcggtgttg ccgttcttct tttcttcttc 51600 ctgatggcga ttatcgggtg gctgggactg gcaagtgtag gtcgtgtggc tgaaatgatg 51660 tcaagttcaa aaaagaaaag aaagtaattg acataacaag tgtaaagggg taagataccc 51720 cttcactaat aaatggagga ttgatgactg aagaagtaac ccctaccaac gaagcacgct 51780 tcctgggact agaccccaat cagttcggaa ctgtgatttt cctctcaagt gccagcgttc 51840 agatggctga ccatataaat tctgaacccg tcagaaaaga aatggaacgt ttgatcagtg 51900 aaggcaaaca cgaaactatc gaaacggcgt tggcctggat tcgtggtcag cgtaatgctg 51960 tgatgcaact gagtggagct tcaaccttcg cgcaaaatct tttggcgcaa gttgaagata 52020 tgttggttga tcaacttctt gctgtaccag ttacacaagt cgttgaagaa aaacctgagt 52080 aataaaggag agaagatgag cgtagtaaac gaatacaaag acccaatgtc cggcaaagta 52140 aactacttcg caaaaggtag catcaaatac atcagcatca aacctgtgaa gaatgctgat 52200 caagatggca ttaagcgtac ccatatccct gcacgtaacg gtcaacctgc taaggtgatt 52260 gaagccaccc acactatcag ctttttaatg caggaagttg atgcggataa taacgtggta 52320 gacccacaga gccaaggtga atggatcggt atgggtgaga agaaacttca cgccagccac 52380 acggataagg ttcaggtcaa gtttgattcc ggttataaag atattctggc tggcatggtt 52440 gtatctttcc cgctgaaagt ctctaagaat ggggataaaa cctatatcaa cggcacttta 52500 agcggtaaga cattcaacat tctggatgaa agcaaagctg gtcaagctgc acctcgtcag 52560 cagcagtctt ctgccccagc agcacagtca ggcggtggtg ttaagatttt cggtgagatt 52620 accgaaatcg taggtaatct ggcgactgtt aatgacgaga agaacggccc cggcggtgta 52680 gttctctccg atgaacagct ggcccaggta tctgtcggtg gacgaatgac tgcctttgtg 52740 gatatgtcta acggtcacat cctgaacgga ttcaaagctt atggacccgc aggtcagaac 52800 agtggtagtt ctggtggtaa aaagagtggt ggctacgacc aatttggtgt tgaaacaggg 52860 cacgccatta acggtctgaa agagttgatg ggtgctggtt ataaagtgaa ggatgagctg 52920 gagacagcta aagccattca ccgtgccaca ttggatatga aagcgttcgt tgcggagcgt 52980 actggtaagc cagtcgattc caacccggta ggtgcaagtg ctggcaacgc aattctggtt 53040 gcatgtagcc gtttcaatgc taagtcagat gtttctgaag caacgattct ggaagcagcc 53100 aaagacgtgt atacaaagct ctctgagccg ctttatacgt tcattagtga aagtgccaaa 53160 ggtgccgatc aaactccgtc acagcccgtc caggagcgtt taacgacacc tcctgcccaa 53220 gaggctccgg ctatggattt tgatgagccg ccgatggact gggacgaaga aataccgttt 53280 tgataaaaga aaaggctccc atttgggagc cttttttatt acggtctttg atagacagct 53340 acatcatata cagtccctct tccacaatag gtcacttgta gaattgtaac tgaatttgca 53400 gcggtgctga tcgtaccacc atttatgatt ttataagacg cctcgagggt gactgcatgt 53460 ccgccagttg catcctggaa cagataaatc gtagcagtaa aagcactacc aagatttgcc 53520 caaggtccga tagtcaaagt atttgtcaca tccacgttat agatgttatt catcttcgtc 53580 agatcagagc ctgtccctcc cggtgtccag gttgtccctg cggaaggcgt ggtaacagaa 53640 ccgggggttg ttcctacgaa attcgcagtg accttcggag ctgttgctgc acctgtaata 53700 acgagggatg caccttttaa agacccgtat gcctctattg tggtggttgc taaaacggat 53760 ttagggttaa tgtcctttcc attgacatca attgaaacac ccgtcaaagt accaagtacg 53820 ttaaggttgt ttacggttgt tgtgcctgta ccaccattat tcaggttagc gtttccagcg 53880 actgtaaggt tggtgcttac cgtagctgcg ccagcaactg cgagcagacc agtaatggat 53940 agattccctg caacagagct agccgccccg gctgtaaatc ctccagttaa tgtgctgttc 54000 ccattcactg tcagtgagct taccacacct aaattctgaa tagaggcact tccgagagtt 54060 gttacaccgt ttacagttag atcagaccct atctcggctg ttgtcgttgt gacaatagag 54120 ttggggagaa tatctaagcc atcaacacca acattgacac cggacaacga accagttact 54180 cttacgtttt caagttctgt agttcctgtt accttaagtc ttggttccgt agaggtcttg 54240 gaagagttcc ctcggatata cacatagtcg aaggtgttat taccgacacc agttaatgac 54300 attgtggtgt tgtctgcact tgctgtccca ttcacaataa ctgcggaagt cagattattg 54360 gtttgaacag aggtcggaga tatgatagtc ttcagatagt tagaggcagc ggtgtagtca 54420 aaagaaagag tggcagtttg tccagataac gaaattttct ggaatttacc aagcacacca 54480 gaggcatcaa tcgtcccccc aaattgtgac gtcccagaaa caaccagtgt attaagggtt 54540 gaagcaccaa ctaccgtaag agcagcataa cttggagaag acccagcaag agaattgatc 54600 gctgctgcga cagccaagtt gacaaatgca gttgtcgcta ttgcaccact attacttccc 54660 tgagcagggg taggcgctgt cggagaaccg acaaatgcag gggtattaag aggtgcaaat 54720 ttttcagaaa ctacaacgga gtcattataa actttccaag cggtgcttgt ggacggatcg 54780 gcaggtaaag tgacaggtgt agatggtgac gctcctgggg cataccacca gaaagtccct 54840 gctgaattgg taaaggaata cagttggtta aaaactgttg tctgtgtccc cgcagcccaa 54900 ggttgtggtg gtgttttaaa atacacatta tcaagaagcg ctttacgtaa tgttggaatc 54960 gtgctaccat cttctacaat aacagtgtcg atcgccgatc cgttgaccac cttatggaga 55020 cgctcagaat cctcgataac ctgatccaca gcctgttcaa attgtgttgt atcagccatt 55080 taaggtctcc ttatttaatt tcttgtttat cttcatcttc cgctgccttt atagctaaac 55140 cccagcgaag tgagattagc ttgcttataa gttgtggagc tgctacagta ggtgcatata 55200 cccacatgta ccattctgta agggttcctt taaatcccca gtacaggaaa acagccgtca 55260 tggatgccag tcctatattg ctccaaaact tggtatgtga ggccttatca gggtctatag 55320 gggacctgac taagtccttt aggaacttca ttattcgagt tggcatttta cctcgggggt 55380 caataagtga agaatgataa tgccctggca agcaccaaca ggcttatgac agttgcagtt 55440 tttatccatt cctttatcgt cgtgtcttta aaatttgcac aaagtatgat aatttccatc 55500 caagtttggt aggaagaatt tattacaaag tcaaagagtc cggggattat taacggaaac 55560 tgcatggata ttatctggca gaagagaatt ggtactgcta cagagagtgt tagctttttc 55620 ttccatcccg ataatataca cgcagcacca aagataaaag agatatccag gaaccaacaa 55680 agattgaggt aaagagatag atcgaaaaac tgggtgtttg aagaaaacca ccatagaagg 55740 gtattctcaa gaaagatatg gaccatgcca agaacagaca tgatccttat acctttgtcg 55800 gaatgaaaca acaaaataat aaagcacagg aaatagaata ctgagcttat cattttgcgg 55860 atctctccat taacatctgg aactgtttgg tgagatctgt tcttaaatca ccaacatctc 55920 ccttgatatc tcttctaaga tctgaaacat catccctaat cgcttttagc tttttatcta 55980 agatatcatc cagcttttct ttagtgacca tttcggccct tatacggatg atatctttat 56040 caagctcatc aaggcgctct tgagtctttt tgtaatccga gtacgttatt cttaggactc 56100 caattaggac aaaggtaata accccccaga ccgccttcag gatagcaaat aggtcaatag 56160 acatagtgcc tccttaggct gtctgcggaa gttctggctg agggtctccc ttggtccatt 56220 ctctgagatt aatgatatat ttcttcatat cctcaacctt atcctcttca cccagtgcag 56280 cgtaagttga tagcagtatc gcggcccttt ggaaaagtcc ttgtttctta ttttcaaaga 56340 ttctgtcttc catccactcc actttttcga actcttcacc gttaaagata taagttctat 56400 tagagaaatc acttgggaga gaatctacaa gacgaaaata acaatcttcc gggaagaatt 56460 tggtagggtc cgtatctacc atatagacct gaccgttaga atcgtattga atatatagac 56520 ctttttgttt ttcttttaat tgcgatacaa aatcgtacca atcttggccg ttctcatctt 56580 ttagatataa ggcgccagga actgcaagct tttctggaga atatctaacc catttcatat 56640 cagttatttt cattaaagcc ccactgtata ccaaatgcca tcaagagctt tctgtaaaaa 56700 tctgaacctt atctcatcaa tatcgtgcag ataaaggtct ccgctggcgt tcgcatcaat 56760 caagccagtc aatacagagc cgtcaggtcc acgcgcaaaa cgtccacctg aaccataatt 56820 ttcaaagtta acgttgactt tgttttgctc accgctccaa cgaatgtcag aaaccccaat 56880 actaatattg acatctccat tagcatccgc tgccgttcta ttcactgcac gaacaatgga 56940 tcttccacca acaattgcgt tgttagagtt tacgacgaga ttttgtaaag tagctgtccc 57000 attaacacca aggttggctg tctggatatt accaccatta ttaatggttg tggaagaaac 57060 tgtacctgtc gtggtagttc ctgttgccgt aatattccct tgcaccttta gcagcgcaac 57120 gccattagac gttgcattaa gctccatcat gttgaatggt gataatgtac cagagttgtt 57180 tacaggaaca aagcggaacc tcatgatatc tacagttggt tgccccgctg ttcctacatt 57240 atcaccaata acgaagtcta aatagacttg atccgtaccc gttgtggtgg tgatataagc 57300 ggtatcgcta gaatcagagg ggaatgttat tctgggtact gtcagcgccc cagtcattgt 57360 atcaccagaa gcatttacat accgggtatc actttccccc ttgctgtaaa catctagagt 57420 gcttcttgcc gttgggatat cagatacatc gctaaggttt tgatcttttc tcagataatc 57480 attagagagt cctgggatct gctcttctga gatgtacgtc atccaccagg tcatcatgtt 57540 aagaacatag ttaagttctt cacaagcggg cttctcaccc aaatcccaac ccttatccca 57600 aagatcagcg ataggggaga ttttatttgc agtatgggca ttaggtaaca cgacgtcact 57660 ttcagcccat atctgaagag gaatagtagg aattgccatg attctccctt ataatagtgt 57720 gttctcttct tcggaggtat agataagact ggataggcca ccagtccctg ttcgcgatgt 57780 gcttacagac ccaaaaccga ttgcatagga atcgttttta aacccaaaag gtagcccttc 57840 tgattttacc agtcgaaggt acgtaggcat agggagcata tcttttattt cttgtatagc 57900 tgtttctatc tcgaaacaac tattaaagat attgatatca aaacgataat tatcaccttt 57960 gtaagtggta aaattctcgg ctccgaagag ttgcttcagc gtcccaatta cctcaggtct 58020 ggtcccgtgt ttagctgtgc ttgagagcag gattgtgata atggcacgat aattcatatc 58080 actcaagcca tttctgtcaa tccccacttg agcaccaatc tcatccaagt tgacccctcc 58140 ggcattctgg aggagacgcc cttctgcaag attgaccatc atctcatcta cagccttcat 58200 tcgttccaaa tacacggata aaaattttac aaggttttct ttttcccgta aaaagtcccc 58260 cggcaggtag tcaataccgt ccgaaacgaa atcatccaat ggatggatgt ggttgacatc 58320 ttttatcgta tctgccataa tccctcttag attatctgta ggaatgtaat attatcagtg 58380 tcgatagaga atacttcatc cagccctgca acaacatcag aggttgtata ggaagtatca 58440 ggatccccga cgttcttgac atccacataa agttgtgtaa atctaccagc agagatagaa 58500 gaacctacag cagatacaag ctggatattg tataaagtgt cagcaatgtt aagcgggtca 58560 ataacacctt tgagggcgga ctttatagta tcctgttcag tggttgagag gacctttcct 58620 ttataacgga cacggatagc caaatcccgt gcctgtgctt tactgtgata aattcgttct 58680 gtctgattat cctcagtagg gacatcataa aaaacgttac cataggtagc gttagacaaa 58740 gcaattgaat tataaagtgc cttgctaata tcttcagtag acccaccata caccacggtc 58800 tcaaacttat acggtggtat tccattctgg tctgtagtcc ctgtgttatt tgagaagatt 58860 ttaaccttac ttacaccact caccccaagg acagcactca ccaccgcagg tctggtcgca 58920 gccgcactcg atgctgttgt gttagaagcc ctaaccttgt attcggtgtc ggtctcaaca 58980 tctgtaccct ctgtgaaggc attcatgttg ttaaggctga tgaacccacc cggtgttggg 59040 gaaatcgagg ttacggtgtt tttctctctc gacagttcac ctgcctcaac agcaacaaca 59100 tccattgtga ttgtacgctc accaacaatc ggtgatgttc tgaaatcaac acggctgtta 59160 agacctatca tctcaagatt tgtgtcatac ccaatgtaca atgccccgtt ttgagaatca 59220 atgatgatcc tatcattatt aagctcggag gtattgttga caataaagct cttgacagag 59280 gccatgaaag tgttaagctg agaactatta ggggttttat tggtcaattg aagagttgtt 59340 tgacttgttg ttccggtgtt ttgattattg atctggaaac tataagtacc tacaacccag 59400 tccttattga gaattttttg tgccagtatg ttaccagcaa gggtggtgtc gtcatttaat 59460 acaaatgtac cactatcaag tatatatgtg ttttgggcat ataccatgtt gtaaggaaca 59520 gtattgttaa ctgtcatctc aacagaccct gaactttttg tttttcctcg acgataaaca 59580 cctcttctgg aaagcaactc atcaaggtaa ataccttcag ccccagcaag ggtctgagcg 59640 gaatagatgg atgctgccag aaggataatc tggtattccc tttcgttaaa aatggttgtc 59700 aacttgtcag caattgtatt agcttgcgtg ttgaaatttt caccaaaagt tctaatgaga 59760 gtctgttttg tgtctgcgat aaggtcatca agagagggga tagtaaaacc gtaatcgctc 59820 aatccatatt gagttgccaa ttcgtcctcc tttcaggacc atgattcttt tgtatatttt 59880 accatacgtg gcagtgtttt gcaaataaac ggaggaagac cataaatgaa aaaaccaccc 59940 cggagggtgg ttagttgccg gacaaagaat cttccaagac tgaaagtcgc ttgtccaagt 60000 cctcctgcat tgcaatagtt gcccgcaata tccagaacag caattcctct tttctaaagg 60060 catactcctc gcctgctggc ctgtcaccat ctgcttccca cttatcgtag cagaatgctg 60120 aatatttggt ccaatcaagg ccgtgtttga gcatgacctt aatagcatct tgcacagtgg 60180 ggccggaatg aagtcttgcg tcacctttct cagatgagta tttagccaac cattgccaaa 60240 ccgaatctaa tttcccaatc tcataaaaag ccctagtttc tgcgggggag atctggcgaa 60300 gattagtctt ctttttcttg ttagaggtag agattacgct gtttactgcg taaacttgac 60360 tccacctcag ggcggtggtg ccactagata tcagattgtc tgtttttgga gagaacgcgg 60420 ctgaagtagt agatatctgg accccataag acctttggga aggacttaag gaaatcttgt 60480 ttacatttgc cccgatctca tccccagagg aagagaaata ataattaccg gatatgtttt 60540 gtaaactgtt cgaaagactg tcaagagctt gttgaacaga ggatcctgag tgtgtcccta 60600 caacagaagc ccctgaggaa cccgttattt caaccctctt aaggatacca atatctgtaa 60660 ttaatttact tattgtagtt ttttcagtgt ctgtggagga ctgaatgatt aactcatccg 60720 tctccaacac cgaagatctg tcagaaagac ttcttatctt tattacagag agatcagttg 60780 ttgccatatc ttaccctcac ccgcttaaat atatgactgt cgaagtatga tctgccctcc 60840 tgcaccactg gttataaatg cagtaatttt attcaggagg cagatcaaag aagctaaggc 60900 tatcaatttt catgacagct acagttgcac tcccgttaaa ccgtcagtcc gtagtttttc 60960 ccccaggcgg atatccagtc atgcatggag gaaatttcag aatctgtcag agcgcggttg 61020 aaaatgaata cgcacgcgat ttcgcaatcc tctactgcgg tatttgactg accattcccc 61080 gtccccacct tgattgtcac gtctgagcgg gtggcccagc tcagtccgtc agccagcgtc 61140 agagaagcgc tcagattctg agtcagatta tacccggtgt tgacccgccc ggagatacgc 61200 tgtgccattg cctgccagag gttatctgta gagccgctgg caataggtat ggtcacgttc 61260 tggaatgaga acgtgttgct ggcgtttttg gcgatggcat gagcgtacag gtttgaatcc 61320 tgcaacgtca gcaatccgac agcgccccca ttacccgaaa accagcttgt cgcatagcat 61380 ttagccttgc cagacagcgc cgaaatacga cgcttcgcta ccgcaaaaat cgtgatatca 61440 ccagaccatg agtagcccgt atcaataaac gccgtattat tgaatgtgta ggagtggtca 61500 gttgttttta ccggagcgcc agctttcgtc agaaggtttc cagtaccgtc atagtttttc 61560 tccgggctat ctcccaccat cagcagggcg cgaaccagtc ccgatttcac agggatattc 61620 actgattttg catatttagc gacttcggcg ctatcgacaa ttaaacgtaa tccagacatt 61680 acagagtcct cactgaaatt gaatatgacg cagagcgatt gaatagcggg taggcgttgt 61740 taaccagcgc ggtgatattt tccccggcat ccagtccgta ccctgtttcg tatgtccatt 61800 tataaatagc tgcctggtcg tcgctgtctg cgatattgtg cccacctgca tgattcgcat 61860 caccaaggac gacggttaac gcgcccgatg gtgagaaatt aggcgtgatt ttcatcactg 61920 tgccagaggc gatttcaact gtgatagccg aaccgtagtg tgtaccatta tcgtcaatca 61980 cggtaaagcc gtaatcgttg tggtcagtaa cggcagtccc tgtatagaac ggctgtttga 62040 caagcggcgc atacagcggg ctgaacgaca cgtaaatcgc ctggccgtcg tatacagcgt 62100 cgagtggttt gaaggggtta agatttaacc cggatactat ggggtaaatc tcttttgcat 62160 attgacaacc cgcccagcga tagctgttcg cgtaccagtg attggcaggg cgtggatacg 62220 ggaactcgtt gtgcaggaaa aatgcgccac ggtctgtatc agtgatgcca atctgcgcca 62280 tttgcacgtt cagtttctgc gtgttccccg catacatgcc cccggtttga taaacgaaaa 62340 atcccggcgc ctccttctgg cctgttgctg caatacagtc agaaatcatc gatgatttga 62400 tatcgttgag atggccaaga tattcagccg ttgtcatccc tccggtatca ttttcaccct 62460 gcatccagat aatgcccgcc acctgcgtct gctcatatcc ggcagtttta gctgcctcca 62520 tgtgcccctt caggcaactc agccagcgtc cgtaataatc ggttaactgg tctcccgtca 62580 ccgggatagc cgatggggag gaaagccccg tgttgacgga tgtgggtttg gcaatctggt 62640 aaatgccagt tgtcgcaccg gaggggaccg ttatacgacg actgatcgga taaactgaac 62700 cggcagcagg attggtgatg gtcagcgcag caactgtaga gttggatagt gacggcccgt 62760 caaaacggat attgacacgc accgtcccgg tgatggcggt tgggaaataa acacgaccag 62820 tcacctcaat aacagccccg gcagtcacgt cgaatttcgc gctctcaacg tatgacgagc 62880 cagaatacag aacgttcacg ccgtcaacgg gcgttaccgt cccggcgctc cagccgctcg 62940 ccgagtttgc gaatgtgggg ttgcccacga cattgtttgc cgggtcagcc gccgtccgct 63000 tcttcagcgc agtaatggat acgccaacag tgccacagca tgaaccggca aacgtcacgt 63060 cggtatcgtt cgccagccct ttgctgcggt tatgattatc tttcaaagtt tccagcaggc 63120 cggatagaat ggtttcaccg aacgtggtgc tgtcagtgga gtcatccgca gtcattgtgc 63180 catcgtcttt ctgacgacgc tcacgcaaag gatagtattt attctcacca ccaacggggg 63240 aaaatgcgtt ctgaatgctc gtatttaagt ttgtcccacg cggagactgt cccagcatta 63300 aattaccgag cgtgctatca gtgcgggtca gaatcccctt cgcggctgtt ccaagcgtaa 63360 atgactgccc gtagacgaac cagaggttaa gtccctgtct gataactgca acagggtgtc 63420 gtttcagatt gtagttctga gcgatatacg ccgcagcgtc ggcactgagc cacacgacat 63480 catctgatac cgatgacgga gcaacatcgc tggcaatctg cgatatcagg tcaacaagtt 63540 cgacctcaag tccgttttta tcctggaaag acaggatact ggattccgat gcaaggactt 63600 taacatcatc caggttcaaa atatcggcgt tcacttgggg gattttgtca acaatcattt 63660 ctatattgcc ggtgtcctcg ttaacgtaaa acgaacagac cgagaagccg tctttcgtgg 63720 cgattgacac tgctggtgag tctatggccc cagtatttat caggctgtcg atgtattcct 63780 gagacggcat ctttcgcccg gtttctacaa gcgcgccacc gttgttaatt acctcaactg 63840 caagaacact atcaccagca taacgataat aggcagttga accaataggt atatttcccg 63900 catctgcgtc tgcctgtgcc gcagccagcg tgggaaactc gcggattgtc cctgttatgg 63960 ccgctgttcc tggaactcgc gcaacttctt gagcaatccc tgcattattc ttgtacactt 64020 tgaacgctac agagcttccg cttccttgag ggacttggaa atattgccca tccgtagttg 64080 cagcaagacc ttcctctgta gaggcgtata ggtttccaaa ttcagaagct tgtaatgtgt 64140 acgcttgcgc ctcatctctt gcctctattg cctcatctcg tgcggcaaga gtttcatcta 64200 gaacacttaa cccacctacc gttacccatg cagatgttga aacaccgcct gttgtagacg 64260 gcgtggagtt tgctggtact gtcttgggga atgtacctcc ccatgtgtaa cattgcgccg 64320 ctgcaatatg ccaaatagcg tcggttccat aggttaatgc tgcgccatcc tcgaaagaac 64380 cttctaccaa agttagccca aggtcatgga gtgctcttct ccataattct ctctcgtttg 64440 cacgggcagt gtcaagactt tgttgaacat ctgttccatc agaggtccct ataagcgaag 64500 caccgccgga cgcagacagg tcttctttgt tagccaagtc caagtcagag ataacttgag 64560 agacagtggc ctttttggtc ttatctggtt gttctacaac gaggtagtcg tcttcaacta 64620 cctgagttgc ggagggtagc tccgcaattt taattgtttc taaggccatc ttttatcctc 64680 caagaaattc gtctgaaaca gtacatggtg actgtcatat aattgttaag gccttgcatg 64740 gcgaaggtgg aacgattaca tgcgccacga cagatttttt tttcactaac cgttacaggc 64800 cgtagttggt gtgaacgtag taaataccat ttagtgtggc ctcttgtctc gtctaaggat 64860 aaatttttag tgattacatt actgtaacca gccaatgtta ttacctgaac gccccttgat 64920 atcaaggtgg gtattgcttg tgccagttcc ttttgcattc gtagggattc caaggtttat 64980 cgctccacga cgacttgacg gtgggctagg cggtaacagc gcatattgtg gcttcgccca 65040 ggagttgccg cttaacgtag cgagggcgct caggtcaggc gctgcgctcc acgcatcaga 65100 ccagatgatg ttattgttga ggataatttg agacgctggg gcaatcctac tgttgcccgt 65160 agacagttgc gcaatgatgt ctgacccgac catccatttg cagtagaaaa tgcagttttc 65220 caccgtcaga gatggaatag tactgctctc agtgtcgcac gcatttgttg atatcagacg 65280 acgctgcttg acgctggacg tgtcaataaa cacacaattg cgaacggtat tattgaactg 65340 gttgcggtgg tgagatatgg aacacgcgtc gtttgttggt gtgccaatct gcccttgcag 65400 tcgctgaata ccatcgttga acgcgaaaca atattctacg acgttattac cgctgccctg 65460 cctgcgggtg taataaaact caaaattgct catcccggca ggaggagctg cctgtagccc 65520 tgcaccatca gaagagacaa acatcactgt acgggcgcac cctgtagagt aaacatatct 65580 gacaacgtta tcccagcaca tcccgtcgat atcaactgcc atattgtcag ttgccatcgg 65640 gtacgaaccg tgaacctcca gtttttcaaa cataacccgg ttacagtgcc acatccagaa 65700 aggtgcatcc cacgtcgcca caccagccga ggtgaactta tcccagcggt acgaactgta 65760 gtagcagtca cgaacgcagc tctgccactc gtcatccgtg tatgcgtcgt ttttgctggc 65820 gcaggtgtga attaatgcgc cttcttgcac gacgttagta aaagagcagc gcaaaacttt 65880 tgcgccatat gttctgctgc cgtcgccacg gttatccgta gtatcggcag cataggtgtt 65940 cccgcgaatg taaacccccg cgttaaccat gttaaacata cagtcttcta cgctgagttt 66000 atgcgctggt gtggcagcgt tatcatatgc cacagcgaaa agctgtacat gtcgcccaac 66060 ggtgtttttc tgcggattac tgacagagta cgcattacca gtgaaataac agtttttcac 66120 atgaacatcg gcgaccccat ccgcgccacc agtacattgc aggttaacgc tggttgctga 66180 cgcccgaaac ccatcatctc tgtccataaa gtgaatgttc tgtaccgtaa tgcgccgggc 66240 ggcccacgat gccagttgcc ccgatgagtt tgaggtggac agccattttg gcggcgggcc 66300 atccccgtat gtgtcaaaaa aactcatttc agacgacgtg ttcactaacc tggcattaac 66360 ggcctccttc aacactgtgc cgcgcctgat tagaattgaa aatgggtagc tggtgattgc 66420 cgcaatagca gcagtaacag ttttaaacgc tgatggaatt ggtttatttt catcatcaga 66480 agggtctacg tataagtatt gcatttgtaa ctcctgttaa gccggctgaa cgtgtaggtc 66540 aacccaatcg gaactgctaa tgtttaccag tgtcccggcg ctcgttctaa cttcgatagt 66600 gaaggtattc gtgccttgag atacgatgtt aactatgtac ggaggtgttc cgaacgaggt 66660 tcctgagaaa ccagcaggag ggcaaacctt ccagtggtct ccacgtaaat tgcagccgct 66720 gataacgtac tgacctgttg acgggttggt gacagcaatt ctcgcttcct gccctttatt 66780 cgccagatga tatggtcccc ctatcgcaaa aaccccgtct gataatttat cagatagtct 66840 gtaagtcata tcaccggaaa cgcgaactac agttcctggg gaatatctga tctcaccgtt 66900 attcatcctc acatagaaac ggtctgttaa cattttctct gcgaacgaat aaaccagatc 66960 gttgggagta tctaccgtta cattattccg caagtcattg tagtaaaacg tcactacatt 67020 ggggttggca acattaatcg gtgtgaatga tattttttgc ccgtatgccg gtaatcgcag 67080 gaatattttt gcaattttat tatcggggtc attaaccaat cctactgctg gcgttaatgc 67140 tgaatccccc cagcccgact gactgccgtg tagagcagtt acctttagcc attgatagat 67200 actaccctgg ttgatgatgg gggcgttacc aagtgcctgc gggttaaacg tgaccatgta 67260 aacatttgat gtatagttta catagttacc cacggacaga ataccggaaa caacttttga 67320 tccaaaccct gagtaattca catcaaacaa gcgataaaga accggtgatg aattttcaac 67380 tgttgggcat tgatcaatcg ttcgttgcaa tgacatgcca atgtcgaaac tttttaccag 67440 tttgaacatc tgcttatcga gagatgaacc ggtagggtat cctaagtcgt taaactgatt 67500 gggactgaca acgaaaaaat cacagatacc attggcatta gttgtaataa gtattcctgg 67560 cgttagatcg tcagactcgc caccagccga tgggaaccga acgatcttat cttcaaatcc 67620 gttgttaaaa tatccggttc cctggacaat tggagtgcca acctgtgcag cagataattt 67680 accgtcaaca accgcatatg tctgaatacg tccgcgctca tctatgacca gtgctgcttt 67740 attattcggg ccgccgaata ctattccagc aacgcctgcc gggtcgcctg gcatctggtg 67800 aatttcaaat tccccgcgct taaatatacg ttcccagaaa gactgattag cgtcgccaat 67860 gctttcagcc ccttcagcag aaaaaaaacc gccaattttc gtatagccat cagactgcgc 67920 caaggccacc agcgttgact gttcaacggt attttcaaga tgatttagaa cttgaaataa 67980 agttgccttc tttgtatcat ctggttgatc aactacgatc aggtcatctt ctgttagagt 68040 gcccgcgctt ggcaactctg aaattttaac actctgtagc atcttatatt tacccctctt 68100 cttaacatta gtacatttta ccacaaactt caaagattta aaagaacaaa ggtctgccgc 68160 taggtagcac agatctaaaa gaaatctcga attgtaataa tttttatttt atggtgttta 68220 tcgtcttatc ggcgggagtg actaccgggt tactttttct ggttaagaga gatcctggcg 68280 gtacagggtt tgccatatca cccgcccaag tattccacca agttgcatca ccagtcttag 68340 gtaatctaaa attgataagg tagtataact tattccccca aggtatccaa ccatcatctc 68400 cgcaaagtgt tgttgtttca gggtttggcg tcgggtagta gtaatcatca gcacccacga 68460 aggctattct tacaatctcc tgctcttttg ttaagacttc aaaaaaggca gaatagcttc 68520 ttgttgtatg gtccattaca gactggaaat ctgcaatttc taaaacatcc ggttcaagac 68580 gggttatttc ctttatctta ttatcaagga ccgtcttcat aactttttta cttatgtagg 68640 ttctgtatgg aaatccaaag gtctcatcaa aataccaatc ccctgcccac acattaaacc 68700 ttagccataa gcgctgtcgt agacttactt gattggattc tatcaactga agacctgtag 68760 aaacatcaag atctccagta acagggtcca tcaagaagtc agaataaaga gttgccatct 68820 attcccctca tgcatttgga gcatcggtat tgttctgacc accatcatct gtccaagtat 68880 agtgatgtgt atggcgaata aaataatcat aaaaatcatt catgtttaca ccccgcgcag 68940 taataatatt gccatcaggg gtaacttgag caccattcat cttaatcgta ccaccagatt 69000 ctgctgtcag gtttgccgca ccattatcga acttgaaatt cccagattgg tcaaccacta 69060 attttcctac tggcgtctcc aacgtgaaat cacccgcagg cgtcattgag aaatgcacct 69120 tgtcgttcca aagttcaaca ttgtctggat cgatcgtcat ggcattccca tcgctgtgaa 69180 caccaattat cgcccaccca ggaaacatat tgtgtgttgt ctggtcatta ttatcattct 69240 cattcctttc tgagaagctc agacccacaa tatcaccagg tttcacagga atcgttaggc 69300 gggcttttcc tccattacct gaaggcattg ataggggaac atcaaaaaca gagccatagg 69360 catccacagt cccatctggg aagtttgtac tcgcaagggg ctgaactgtt gcagacggga 69420 tgctatagtc cacatcaact accgttgccc ttagccctgt gtgaatatct ctggcctgtt 69480 ttgcaaacca ctgattaagt gctgcatcca tacgggttat tgctgccatt aggcctccac 69540 aattccacca cgggtttctg caagtcctaa ctctgtgatc caatccccac cttcgagctg 69600 gcctttgtga gttaagtata caaccttgta aaaacctgtg tatttctggc tctttaaaaa 69660 tacagttgat tctggtatga tagcaccatt catttctgtt actaccacca acccagcgtc 69720 ttcttttatc tctgctgaag tgggtacgtg gggcttagat gattttctct tagacttggc 69780 ccttttttcc tttctcctct ttgcaggctc agggttctgt ggcgttggtg aatcatgcat 69840 accagattcg gcactgatct caaaaactgc cctttgaaac cttttccctt gcgtggtcca 69900 atatacagca ccatcttgaa cactgaaagt agatcctgta ttcttggcta atctctccaa 69960 gttatttgcg gcgaggcccg taaaggacat agagtgctga agcgtttggt cgccaaactt 70020 gacgatcttc ccaatgggga gcttcatatc agaagcaagg tcactgacta ccgtgtctat 70080 tggcgtacct ttcttataag agcgagaggt ctttgccgtt ttaatattta ctgttgcatc 70140 cccgaggatc atctttgtct gacgggtatt gccgtcccac ttatcctgaa caaactctac 70200 ggtcccagaa aatatagtct gattctcacc atcaaacccg gcctcaagaa cgatcgcaat 70260 ggactcacgt tggttagcat cgaggtagct caccgtctca tcggagaggt tgtagatggt 70320 aacataacct ttattaggct ccttcgagtt gtcttttttg acctcgaact cgatgtttgc 70380 ggcaccagtt tcattactga tataatacgc atctttagca ttctggttgg tatagtcaga 70440 tatattggta ggcttttcac caacatacac tggtttacct atcgtcagct tataggttct 70500 tgttctgtaa gcaggcattg tttactcctc atcggttatt acctcatcct caggagacga 70560 gtaaagtagt tgcaagtctg acaaaaatcc aatattgtat ctccctacac gtttagtgga 70620 ttgagtaaaa gaaaatacac agaggtctcc tgccggtata ttgtccaagt attggaatgg 70680 ctgcaaaaga ttaaaaattg ttgtcagttt aaaggaaatt gtaggtgtgg aaccgacatc 70740 accaaagtat actaaccaag actcgtctct ctcgttccat tgaaaacgca tttcataagt 70800 ttgactgtcc agaaccacac gcatggtctg gtccgcaaac ccatctatgt cccaagtgaa 70860 tgttattttt gccattagtt acctaccacc ttgccataat caacaacatt accgctgagg 70920 tcctttaact tgccatccgg ggttagtgta cccactttct catcttgcat agtcctgcct 70980 gtaacaccta attttttagc cctttcttgc caactatctt gattaggccc agcaaacttt 71040 gttctccttg cagtgacgtc tacttcgtca tctgtagccg aagactgaac agagcctttc 71100 tgctttgttt tccccccaga ttttttaggg tcggtatata ccgtggctaa ggctgtcttc 71160 ccaagagtaa aagtacggaa ctcagtaaac tcaagttgaa acaccagcgc tgccccatct 71220 gaattgctgc ggcttgcttc caaagaggta aggatataat tttcaatgat gcggtcttcc 71280 gttacaagcg taacgatttg gcggtcagtg atgagccttt ccaaaacctc caaggccttt 71340 tctgggcgtc gggattctac cgggttgtta gggtcggtgt ctttgtcgat gtagttgttc 71400 tcgatcatgt agagtggcga gctattgatt ctcgcactga aagagaattt cccatcctca 71460 ataacgccgt ggtcactata ttttactttg ttttcaacag cgtatgatgt cttgtcaact 71520 gtccgggtat aagagtgatc ctcaacaaca tcaaaaagga ttgcaatgtt atccgtatag 71580 tttttattct ttagttcaac gtttctgcca ccgttattaa gtccgctcgc aaacaatgta 71640 tattgaactt cactactggc attctgagcc gtagagactt tttgctcaac gtttgctgta 71700 gccttacctt gttgcggttt ggactggttg cttgctacaa ctgccataaa gcctcctcaa 71760 taagcttgtt atgattttat cataaatctt caaataaaac aacgaaaaag gggccgaagc 71820 cccttgtatt aatctgggac accaaggatc aaattgatgt tacccatatt cgatgcttcg 71880 atctgttggt caatcatatc cttcagctct ccggcatcca gtttgatagt tatctcacca 71940 gagacaggct cagtagggat aaccattggg ggggttggtg ctgaggttgt tgctcctggc 72000 atcattcctt gattttgcaa ataatttagg cgggcttttt catgttgtgc tcctagtgat 72060 ctccaccagt tcatgatatc atcaccgaca gtgggtttat tcgtattctc ttcaaccttc 72120 ttatagaagt ctggttgttg agtattttca tatcccatat caagtgctgc ccaagcacca 72180 agaataccta atcctgccgc acctcttctc catccaaatc ctttacggcc tttaggagat 72240 cttccacctt taccagttcc accgcctcct gccccgctat cgtcaccgcc tccaccaagg 72300 acagcaccga tagctttgat cgccccagca aggcctgcaa tcttagcgag gatgttgaac 72360 acccggacta gagatgtcgc aaagaatata gcacctatac cccagccgac ccagttccat 72420 gctttggata tttcatcacc cttatctcgg aagattggga tgtactcttc aaggagggcc 72480 tttacaagta tgaaagagtt atataattcg taaggtatct tcatgaaccc gtctatgaat 72540 cctgcgacaa actgacccac ggcggcggcg agtggaccat tagaatccaa gatcttggca 72600 agggtattaa atgtctctgt catcttatca ccgaatccag attcgaagat cttgttctgg 72660 aagttcatcc aagtctgggt aaggcgttgc atagcaaccc ggttaccttg taaagctttc 72720 tgtagtgcgc cacccttgtt agcagcttct gcgtagtatt tagcaacaaa cggaagcact 72780 ttagcagcct tcagctcccc gttcttcatc atatccatca atttggtaac gtcgatggtg 72840 gagtcgttga atgcttcttg cgatgccttt atgaacacct gtaatgatcc tgggatacct 72900 tcagcaagct gttgcttaag ttcttcagcc atgatctggc ctttacccat catctgttga 72960 atagctgtaa taccgcgttg gtattttaca gggtcaacct gaagggcagt tgcatactca 73020 gagaatgact tgaagagctg atcgttttgt gatttagtaa gtacaccgtt tgctgcgata 73080 gacatctggg tataaccctg tgctgcaacc ttaaggtcga gacctaaacg atacgcctgg 73140 cttctcacaa attcaatacg cttaccagcc tcagcagaat catcggagac catcagcatt 73200 gttgcttcca taccctggaa gaactgccca gttttcagaa cgcttgcagc ggcattgaac 73260 gctccgtatg ctgctgtaac actgattaat gtgctgcgta gatttctcag gccatcattc 73320 aaagaaagag tattagcgct ggccttacga agtccggttt ccatagaggc aagttctgcg 73380 cggaaatttg atgccttcat gttcccgctc ttcatgtatc ggttaactaa ggaatcatag 73440 ccgggtaatt tccttgcata tttatcacca tacttggcac gaagacgaac attggcgtta 73500 gagattgtgc taatcttcgc ttcccgtgct cttgctcttc tcccagcttc ccgctctgca 73560 tcgcgggcca ttttctctct ggccttattg tcagccttat cctgttttac ttgttctcgg 73620 cgtattcttg catggtcacg ttccattgcc ttgcgttgct gttcagcaac tttcgggtca 73680 taagccgtag catttgcatt gagaatcgga gatcctccgc cctgagaacc cttatttttc 73740 agacttgctt catatgctgc catacgtgca gcagaaatgg aagggttagt tccataagca 73800 ccgttcttag cagcaagttt ttcttgttga cggagctgtg ccttcagggc attatagttt 73860 gcctgcgact ctggagatcg accagcagtt agtctggaga cagcagcctt acgtcgtgcc 73920 ttttcaatct tatcaatggc ttcacgagca cgagcttctt tctttgccat tgcgatattg 73980 tgagctgtgg tcttagccgc ctctgcacgt tcagtttgat tgagtcgttt attaaccatt 74040 ctcgcctgca tggcggaacg tttcagggca gcagcagggt cggccttagc agaagaaaaa 74100 gccttcccgg tcttttccca ttcggaacga atttgcttta cagctttcaa ggcgcgtcca 74160 aaggatgttt tgtcaacatc ccatgtcacc ttgttgactg tggaagtcac tataatattt 74220 gccataattt cctcaataaa aaagccaggc tcctgaaaag gaacctggct tgagattaac 74280 ctcttctgcc tttgcttcgg ggtttagctg cttcggcgtc tgctctcgat ttctcttctt 74340 tctcatggac atcgttgatg aaatcttcga catcgagata ctcattgagc ttgagcaaat 74400 attccatatc ggcagactca agggagatat aagactctcc cttaaagttc ttcagagcac 74460 ggcaccagag atagtcgaac cacgtcaggg aactattttt tcttgcataa tcaatagctc 74520 tttggacgac tttagaaatt ttggacggtg ttactccgct gccacttccg tcggttcctg 74580 atccaccgtc gccacttggt gaaccatccc gaagttgccc agaagtccct gaaggtctgc 74640 gaaaccgtct ttcgtgaaaa aacagccgta gttaatcttc agaacctccg ctaccaattt 74700 gatcaggtcc aacatcttat cctggaagac cgtatcaata tcaatcttgc cagccattcc 74760 gttcacagac acatcttcaa ggatgagttc gaataatttt tcgatatcat cttgctccat 74820 ctgctcaaat aggtatagaa ttgcggtagg tagtgcttca gagaggttag accctccggt 74880 aaacaatgca ccactaatag tagccattgg aactgcgata taacgaccaa tcttcggaag 74940 gtttttcata accttggacg gagaccagtg tgtgattaca aagttcttac cagctagatc 75000 gatttctgtg gtaggtctaa aattcatcat gtgtacgctc ctgcgtcttt taaggttgtt 75060 atatccatgc gtgtttgaaa aggccacatc cttgtggcac acgaaacgct attagacgat 75120 acctgcaagg ccagccagac cgaagcctgt agcgtacaga gtatctgggc ttaaccatgc 75180 gtccaggatt ccgatttccc aatccatctg gccaacttca gtaccgtagg tcaggtcagg 75240 ctgtttctga atccaaccaa ctgtgctcag acccatacct tgggagcctt caagaaggac 75300 agggaagaaa atcaggccag tgatggaagc ttgtttctgc cagttagcca agtatccgtt 75360 ccataccgaa gtgttctgta gagagaccgt caggacacca gattggttac gagacagcgc 75420 tgctgacagt tcaccatcaa cccccatgtg ggggatgatg ttatcttcgt tgcgagcaac 75480 gacgatcttg gtatccgctg cgaacccagt gacgcgctga gtcatcatat agagacgcgc 75540 tttctgtggg tcgtaagcat acggggttaa aattctagta tccatttatt acactcctgc 75600 tgttacttgt ccgctggaag aagtagaccc ggttttgtct agcagaacag agatgcggat 75660 cttgacgaaa tgcagggcgc tgttgtagac tagctctacc ttaacgttgt taagagtacg 75720 agatgccaga tcattagatg gtatgtttgc acgaagcggg attgttacaa ccggatcgta 75780 gaacaccttg ttgacggaat catacccggt aagaatagaa ccgttggtga taccggtatt 75840 cagaggacta ttcatcagga ctgacttcag gttcggcaga tcatcatcgc tcattttcat 75900 ggacaggcca agattagaac ggcgagacat gtaagcgaag atactttctt cacttctgaa 75960 cttcagccag tgaccaaaac ggacaacatc gacatactga ccggaggcac acttaccttc 76020 ccagaatgcg ccgacgccat taatcatacg atagaagttc aggttctggc cccagatagc 76080 tggacgctca gaagaactca gggtcggagc aataacaccc ggcattgtct tcaggtggat 76140 tgagtcacca taggatgggt cattagatgc cattgcaccg atgataccac cttcagggaa 76200 tgcactatca gcaagcgggt catacatacc aatgctagta tcatactgaa gtgctttcag 76260 ttgattagca atagaatctc cgtcgacaac ttttgacagc ggatcggatg ttgaatagac 76320 gtgcagctta tagttagcag cagcataagc agcagctccc agaattgcag aagaaacgtg 76380 ttgttctgtg ctcaggaagt accagttgct gtttgcagtt tcgacctgtg gtagaacacc 76440 gcttacagtc tcagttgagt tgttagtcag tgtgcaatca cctgagtcaa taccgatgct 76500 gaatggctcg ccgataacat cagaagatgt tgccatgatg ccttggtcag attcggttgt 76560 aaccacctca tcatcgttag tagccagcag agagccatca cctttcggag tgattgttac 76620 aacaccagtt gtagctactg caccgacaat tacattaagc gtggtatcgg agttgattgc 76680 agatgccagg gctgttgcaa tactctctgg tgtagatgcg gtagtaacag gaataacgat 76740 gcttttagta tacgcacctg ctgcaacgtt gaaacttacc gggttattag ggtctacgtt 76800 agtctgccct gtgaaatcga taactgttga ttcccatgct tgtcttccga tcataagcgc 76860 ttgggggcgg aaagtcccag caaaggcttt tgtcgcaaaa gtatacgcag gggaacctac 76920 agcgaaacca tcagcagcga gttcatccag atctgtatat gtacgtactc gttctgggaa 76980 aacgttgtga attgcgataa atagaggggt ttcaaaccct acggtgtcga ttggttgtgt 77040 cccgagaaca accgttacgt caacaacctt atcattataa gccattgatt tcctcttctt 77100 ctatttcttt cataaagtta ttgttgatca tctggagccg gatagtaata aaccatctct 77160 gcattcaccc tctcgatatc ctcgaaagct cctgtatctg tcactccaac gcagacgtta 77220 aaagtgataa gtacagttgc acggttttcg aaggtttgca tgttcaacgg aactctctgg 77280 cgcgataccg ttgaggaaga agaatatgca aatggggaat tggttggaaa atacttgtcg 77340 cagatgtagg ggaggctcaa ggcctgtaga atccgagtta atgcatttga tgcttttcct 77400 cgaaatgctg tcaggttgta aaccacctcg tagttgtgag ttattacagc gttaccgctc 77460 tcatctaccc actcgttcgc agcccagtcc atctggtcag cggtaacttg gttgagcatg 77520 atgaactcac cctctacctt ggatatgacg tctccgtccc cgtcaattat ttttctcccc 77580 gtgacttctt tgcaaaatct ggcgagcgta actgcgaggg cgtcaaaaat atcatcggag 77640 tttgttacga agtctgccat cataggcccc cttctgtccc cgcaggcgta gagatcacat 77700 acgctctgta acggctcacc cctgtcgtct gatacggatc agacttgata acagtaaacc 77760 attccatttc cccacgggaa ttcatgagct ggatttgatc tgctagcagg aaagaacctt 77820 cgacaggacc tttaagaaga gttgacgaat atacagtgaa tgaatcatac tgtctgccgc 77880 cagcctcggt caactgcgaa gtgtagtctc ttgctgcctt gcctgtcaga ggctgaacaa 77940 cgcattccaa gacatcaaac tcttcatact gaatagcgat ctcttggttt tcgaatggat 78000 tgtctgggtc tggctgggaa aaagtacgat gtctcccgat gaaagtcttt ctcggaatca 78060 gcttattcct gcctattagt ctgtagcctg gtgtcattta gtccccttcc cagtggaaat 78120 cttataggtt gcagatgact tcaggtctcc gtagtggaac atggcctctt taaatccttt 78180 gacatcagcc catgcatcag atacgaggtt attggggaaa agcccgccat cgatgacgta 78240 tcgaatcttg tctgcacctg cttgaccgat ttgtttcagg actggagtcg ggtcttgcgc 78300 tcccgcagcc aattgaccaa agaggtcgat ctgaaatttt ttaagttctt tctggaaaag 78360 aacacccgcg ctggtcatga aagtacgagc cgggaggtta ttccaaccct cttgatgaat 78420 cgctgcaaga gttgcagtat tcaggccaga atagtgagga tcgtcgaaaa agccgtagct 78480 tacctgacga taatcaagct tcttaaccgc attaaagaag ttcataagct ggctaagatc 78540 ttgcgtactt gtgaattttg gtatcatgac tgcatccgtt taggtatttt accacattat 78600 cttagcaaaa tcaacgataa acgtttggat agttagcaag gccaacggcg agggtatcga 78660 cgaggaattc ctggaacacc agtctgtgga attatacctc caacatcgaa aggtccacgg 78720 gagtttctgt cgtatttaac acggttgaac tcgtcttcac gaactccccc aacgataaca 78780 aggcctctga ccgcacttaa gcaatcattg acatagtcag ggttttcaag cagccagtcg 78840 aggaagtctt tccaattctg ataaggagat ccacctttga tctggatagt ttcatcacca 78900 atcttttcaa ggcgatccgt gatcgatgcc tctcctgtgt tcacttcctg aagaatcaac 78960 caacgtacca cgtcaacaag agtattgtaa ataacgtagt aaacagtgca tggcgtgtta 79020 tcatcaccgg ggtaattagc ctttgatttc tctattgcca aaaaggcaag gataatctcg 79080 tcgggtaaga cttccgggga aatggaccca aggagcaggc ggatataagc aacaatttct 79140 tggtctgtca ttttcgctcc ttcaagctct tctatttatc aatatcttat catagaacgt 79200 cgattttgtc atcaaaaaca cttgacatca tgtgacagga tgctattctc aaagaaaatt 79260 attgaggaga atcccatgaa agcagtaata gcaggtgtta tcacagccat cgttgtctcg 79320 ggtggactta tctactttat gaaaaccaac cccaatatga acaaattcga cgatgtttct 79380 tcaagctggt tggcggctga agaaaaaaca gaggccattc atcggattgc tgggatgaaa 79440 tgcgatacag aattcagaaa ggcattcatt cccggcactc tgacgacgca gacaggtatg 79500 ttagatgaga tggaagaaca agaagatagt ttccaagtaa tgagaaatat ggggatagtg 79560 aacggtactg ttcttgcaac aggaacttac atctgtaaat attataagga tggccgacaa 79620 ccttatcttc aggtatcttt gaaaccagag gcgagaccgc tactaaaaaa ataaggcccc 79680 ggagggcctt tatattacgc cataatgcca gcagccttca gcttggaaag aagggcatta 79740 aagtcggtaa ccagtccagc tacgtcagtc gcaaccgtat tggcctgtgt tgccgccatt 79800 ttaacaccac caaccacaga agtggttgca gctacgggag caaaagtagt aggcttacca 79860 gtaatatcgg cccatgccac agatccgcca ctgccagcgg cagcaataac atcagcgaag 79920 gaaataactc cgccagttgc aatgtcaatc agttttgtac cgtagaccag tccagctaca 79980 ccagatgttg ccattttaaa tctcctaaga ttattacttc agtgcggatt cgaagtcagc 80040 taacatattt tcaaatgtct tgctcttcga cagggtaaca cccttgtttg ctgcgaattc 80100 agcaagtttg tctttactac cttttttgtc ggcttcatca agcagtgcag atgcttcagc 80160 aagaagtgcc tttacgtcca cagagtctgt ctcaatgatt tctgtattat cttctacaac 80220 ctgttcaaca acggtttctt ccgcttttgg tctaaccgta acaggtttaa cttcagacgg 80280 aggtgtaatg tccccgttaa agaacacgat gaagttgccc attctcagag tagaggtctt 80340 ggcgtctaca ggaagaccgg acaggtctgc aagttcctgg aaaaactcca tgaaagaacg 80400 aaaagccttc atttgcttac caaggacgaa gccatttagg ggtaagcggc ttgaagcgct 80460 aatgttcaat tcgggaatgt atgccccaaa gaacttgaaa agctctacct tgttcgggaa 80520 aatgcgataa ttttgatttg ccatagaatc tcctttggtc ctcataaacc tcttgacata 80580 taagaccacc atgctaatct taaaatgaaa aaagggagag gtgattaaca cctccccctc 80640 ttagaggtag ctttaagcta tattacgcga aagtaccagt cagtttaaca accagctctg 80700 ggcggcagtt aactgtcagg aaggaggttt cagattcaac cttctcttca cgcaggtaag 80760 cagaagattt gtaccacagg tacagttctt gtgccggagt gttcgcttca cgaacatcgt 80820 ctgctggcgc gtagtggatc tggaacatgt tgtcgatacc gcgtggcagc atgtaagctt 80880 caccgtccgg gatgtagccg gagatatctt cgatgtacag aacattcttg tgaacgaagg 80940 aacggttgtt agcgttctct tgtccgtcac caagacgacg gcgcagcggt tcttgagtgg 81000 aactgtagta ttggtatgcg ttcatgatca gcgggtgacc tacgaaagca gagaaccatt 81060 tacgagaagc caggactacg atgtcgtagt tgtttccgtt gtcaccagcg ttgtcgatga 81120 tgaatgcacg accatcgttt tcgagcaggt cagacgggtc aactgcaacg tcagtgaaat 81180 ctacgttaac aacttcctgg gtaacacccc attcggtgaa gtagttatac tgagcggtcg 81240 ggtcctgcgg tgcccaagat ttacccatga ttgcctgaag cattgctttt tctttaagct 81300 gttcatgaga aacacggata cgacgaacaa cgcgttcaac tacatcctgt acagatttag 81360 gagcgtccgc agtgaaatat ttacggaagt tctgtacgtc tgccggagtg atctgacgat 81420 ccagcgggaa gaacgggatg ttgaagtttt tcagttgggc cttttcagta ccaacgtagt 81480 tacgttcacc ctgacgacga cgagctggga agtcggttac aacttcgtca acacgctcaa 81540 tctgggcgat agtagagaca ccgtgataag cctcgaaaag gttcatgttg gtgatcatac 81600 ggtactgacg aggtacaatt tccagagttg cgcctaggtc aacgatctgg aaatcattag 81660 tgcgtactac tgccattatt ttctccttgg tgtagattag atagacgtta ctgggatctc 81720 aacggagccg tcgtaatatt tatcagtgat cttcagacct ttggcctcaa gagcagcgat 81780 agcagcagcg ttgatagcag tagtaccgtc agcaaagaac agtttggatt tgttcagggt 81840 cagaccacga acagcaacca cgaaattgta tttttgacca actacgaaag gacgtggcat 81900 ggtgtaagaa gaagtcacca ggtcgcggtc ggtgattaca ccaaatgcgt ttgcagcgtc 81960 ggcagttgca gccagagtac catcagactt aacgatcata ccggccttca gccctgcgga 82020 ataagtgatt tccatttcca ggaagctgta gccctgatca gaagaatcaa ctttacccag 82080 gacgatgtca gagtagaacc cttgaatcgg attagccatt tatattatct cctcgatatt 82140 aggcagtttt gcgagcgcga gcagcttcta gagctttctg cacgttagct ttaagaacat 82200 cttcggcgga cttagctagg tcttcagtaa caacctcttg gttgatacca ttttcctgag 82260 taccgaactc tttcttcaca gtttcaactt ctgtttccag ttcgctaata cgagcttggg 82320 ctttttccag aagagctacc actggggcgt tagctttttc aatgatgaag tcagcaagag 82380 attcatggtc ttcttcagcg gcaaaagtaa aacctttggc ttttgtaaga gcatttttct 82440 tttctgcttc aacagcagcc ttaataatca gttctgcttg ggcatttttt gcattagctt 82500 cttcaagctt tttaaccagg tccaggtact cctgggattt ggttacatca acagtatcgg 82560 acacagaggt ctccttgttt tcaattgtat tttgaacagg tacgtctggt ttagcagcgt 82620 ccttgatgac ctcagtctcc tgagtgtctt tggcatcaaa aatgacaccg tgctctgcaa 82680 cacccttctc aaacatctgt tggagtttga ttagttcata ttgcttcaca aggtccagct 82740 cttcacctgc atttgcagct ttggcgatag agatggactc catcttcgat tctaaccatt 82800 cttggttatc atcattccaa cgttgcagcc attcatcatc aggattttca gcagcagcgt 82860 tttccagttc tgtttcgaag cccaaaagtt tggcaaggag ttcagcatca ctactccaca 82920 tatcgaagaa gcgacgaagg aattcttcaa agctcatatc gacagtaact tggcgaagtg 82980 ccttaaccac gtctttggta atctgttcag gtgcaaggtc agacttcatc agaagactaa 83040 ccggacgcat atttgcagaa taaccttgac tctcgtggca gagtgcgata cccttatcct 83100 taatagtttt ggccttgact acgagtgcgc tcattcgttt tcctcggcaa tctcaatccc 83160 gaaatcgagt ccggtgattt caccagtctc cttgtctgtg tagccagagc attgaatgct 83220 cagtccaccg acagcgttgg cctttttcaa gagccacagt tcaggatcat tgtatttaac 83280 cttagctacc caggtgccag ctttaatgat ttgctcgcta ccgataacca cgacatcaaa 83340 ctcttcttga atccaagtct tctcgatggt aaaggcatca gtctcgacaa tgtggaacag 83400 gttctcttta acaagaccag ccgctcgcgc agcatcgaaa ctttccttac ctttgacgat 83460 tgtctctgga gacatccatt caccgtgggc atccctagtg tttggttcat aaatgacttc 83520 gtaagaaatc atttgttctc cagcatcttt gacaacagat acaggcttgg cattcttttg 83580 aattgctgtc ttcttcagcc ctacatggag tacatcttta gatgctttct caatagcggc 83640 ttcaggagat aggcctgaat caatcaggcc atttgcgaga accagcacct tgctcttctg 83700 aatgagagac agattcgata ctgatgcagg aaggtcagca atacttgagt atttcatcat 83760 tttccccgtt gatagttatt ttaacaccgt ttattttctt ttgcaagtta tttcagtgag 83820 ttgcttagtt atccaagtta gagacagaat tatctcttac tttagacgtc ccattaccag 83880 aagtaccttg cttcattcca tcaccggagc gactggtatc ttccccaagg atcttgagta 83940 gttcctcttg agatgtgttt tcaggaatct cttcatcaaa cccaccaacc tcaaggatct 84000 tgttgataac tgtaggtgtc ttcggcagat aaccaacagc accaattctc tgaacaaatt 84060 tggagaagct ttccatatca acttcctgga tagctccagg cttaagtctt ggcatgtctt 84120 catcagacaa acggatatta ttaagagcga gtagttgagg aatcaagttc ttgttgaatg 84180 attcacaaat aatatcgata tctcgttgaa caaaatgccc gtggattgtt tgttttgatt 84240 ccgacaggtt gtaagaccct tgaccatcat tccctaagtt gatgaatccc gcaccaaatc 84300 tgtccaagat cgccttctta cgctcttgta ttaggtcctt ggtactgtac tgtttaccaa 84360 ccccatcgat tcccttaagg gtcatcttat actgctcacc gcccttatca ttcatatctg 84420 aaggtaagat gaagtaagat tgttcacctg aatgtgcgtt tgcagcgtca gccatcaggc 84480 cacgaaccat atctgcttca ggtgatctcg ggtccataga tgccttattc agaattgaag 84540 aagggatctt taattcaatg ataccgccga ggtccttaga tgcccctata acttcgaggt 84600 tttcgatcag gattttttca cggaatgcac ggtaacaacc aacaagaggt gatacacctg 84660 tagggtttga ttctgtccca ccaagagaca ttatcatcaa cttattcaca ggaatgaatt 84720 tctcatccgc acttcctgac agatttgtga cgagactcat ggccccagca atctggttca 84780 tcccgttctg gaaattagca aaagctagtg cactttgata aacacctgtg attgtccttc 84840 catcatcgct gaagacaaaa ggttttgtac gagagaggct tgactgagga cggaaagcaa 84900 ttttgtcgat cgtcatatag cctgcgtact tagatggcgc ggattctgtt ctgtagacct 84960 tttcgaatac agagaaacca tactcgttaa atgtcgcagc acttctcgcc acatcgcgaa 85020 gcgtctgttg gttagcaaga ttcttcagag catactcgac gaaatctgcc gcttttttag 85080 actcttcact atctcggttg aaaagaattt taaaatcatt gaaagccttg gtgacaaaaa 85140 catatttcgt atccagcgct gtggcaacag tatggtcttg cttcatggaa tccactgttg 85200 cgaggaacat aggccagcgg agttcttcaa ccttcataat ctcagattca gcacgaatct 85260 gagacaatgc tccactaccc agttctccag tacggacacg actcacagca aggttttcat 85320 tccctgcttt tgccaccgca ttctttcttt ttctgtttct gcgatttgac acgagtcatc 85380 ccctctatta taatcgtgta tacatagtcg gagcaacaat ccttgggatt acgacaggtc 85440 tgatgatctc cgttttctcc aggaagttaa tacctgaaga gatggcgtca acccagtcgt 85500 ccttacggga cacagtgctt cgctcgccat taaatttctc aagttcattc atgagggctt 85560 catatgtctt tgcgtcaaaa ctgttacgga caatacgaac aaagccttgt tgtgcaagct 85620 gggcaaaggg tgcgaaacga gtaagtttcg acttgttgcc tggcgtaggg tctttctcaa 85680 ccacataacc atccgcgagc aatgctcttg agctggtgag gaattcgctt ataccagctt 85740 ggcctgggtc aactgagaaa ataatcgtta catcatcgcc atcatgttct gcttgttttt 85800 tgataattgc atcacgttcg ccagccttct tacagaagcg gccctgagtt cctgtggaat 85860 agagaccatc atcaacgaac tcggcacaat aatcaccgga taaatagtaa aaaccctcgg 85920 tgtctttact cactttcacg gaggctgtaa agtcaggatg tctgttacca gatgtccttt 85980 cagttcctgc cttatcgtat ggccttacag atgtgcaacc taaaggtaga catgccacct 86040 ctttcaaata ggatctttga aaatagtttg caccctcagg gcgagcattc cagttaccat 86100 aaagtaactg tgccttttca acttcaggaa gccctttcag gaatgccaga tattctttgt 86160 tattctccag catcggaggg ttatcataaa tgttagcgga gatgaaggaa aatgtcagag 86220 catcgtcggc gtcatcacca taaagctctc tcagttcttc ttgagactcc ccccagacaa 86280 agttaccatc ttgacggagg aaccaacgga tgacaccgtc acgctcaggg attggatatc 86340 catcatcgtc aagataccaa tcgataagtt cttttatttt gtgatccggg tccgggttac 86400 aagaaattac catgcggctt gggtatttag attcagaacg tagacgagag attaggtagt 86460 cgatctgctc ccattcgaac tggcatcctt catcgaaacc aacaaaagtg tactgaagac 86520 cctggtggtt aagtttgtcc ttcacatatt ccatgtgaga ccattttacc tttgcgccag 86580 gacgaccctt tttgaatgtc tgtgtctccg cgtcaaagta tgggaatatt gcctcaagct 86640 ctttctctct aaagcgtggt ttccatgcat caggtagctc attataaatg ctttgtgctg 86700 tatcaaataa accaccctgg cctttcaact gaggtgtggt tctacggaac atgatacagt 86760 tcgattttgg atcatcgata tatgctaaag gcattaattg taacagatac gatttacctg 86820 accccgcagc gcccccaatg atcaggattt gcgccttatt ttccaggatc attttctgct 86880 tagggctggc gggtccaaaa gtcttactca aaggacctcc attattatat gctataggag 86940 gattttacca cgaaagatca taaaaataaa gcccttatca cgaaataagg gccttgtcaa 87000 tcacttttga ggtgtaaata tgttacgaat gtatgcctga aggataagta acttgctacg 87060 tgtatcagct gcttcaagat tatttttctt aacaatagca ctgtttttag cgttatcagc 87120 accataagga agtggtgttg ggtcagtagg tgggatcata gcgtgagcag ggggcttaga 87180 aagcacctca gagggattaa acttatcaac cactggaact accttctgtg gagactcgca 87240 tccaacaagc atgattacag agaggaatat ggcaagcaaa ctctttctca tttaaccccc 87300 aagctttcat tatagatatc aacaaagtcg ttatccagcc caaacttttt accagcttca 87360 gatttgttat atgcctgttg tttttcatcg agtctggatc taagtaaatc attcttagcc 87420 ttctcttctg caagctggcg actaagttca tcagagaagt cttgctgcac atttttgaaa 87480 tcttgatttg catctttgtt gtttctcatt tgcagaaccc atttgttatc cgtatcatta 87540 accccacggc tataggcctg ctgtatttgg tcatcatacc accacttgac ttcaaaagcg 87600 ccccacagga gcgccagaga aaggacagca acgataacca gtttggtgtg tccctttata 87660 aaggtccaaa ccacactgat aaaatttatc atgagatatc cccatcacaa tctaataatt 87720 caacaatagt caccttattc cgaggagcct tatcttctcg gtttacagac actcgcccat 87780 ctccttcgta ctcaaggata agcggatctt ccacgataac cttaaacaga caagcaccag 87840 gttctatctc ccctacgtgc caactcccct gaaccccatt cttgcataag agcttgtacc 87900 tctcttgtgc agcatcaaga tcaaaataaa tcctgatctt atctagcatc tctggattgt 87960 cgatgttatt gctattaagg ccgaatacgt gtttttcggt atgcgcctgc atcatgtaaa 88020 aatgcacagc actagataca gcccagaatt ccttgaaata caggcgatcg gtgtttttac 88080 gcaggcgttg gaaaacattg aagatatctt tagcttcgag attaaaacgc cgttggcctt 88140 tacgcttgtc ggtgatagtg gcaatcgtgc tgatagcaat atcacctgca ttatccagtt 88200 tatcaaataa tccctcaaat gaaaacggct cttttgtatc gaagagttct tcaacgtttg 88260 tcccatacat accgctaaga tgctttttgg catcttccca gctttccatt ttgagacttg 88320 cgacggcaac acccaacttc attgtttctc gacgggagat tgtataccca cgggcctcgt 88380 actttgacgc tcggagcata ctgatgatcg ggtagtctgt cgctggatta agaaccaaca 88440 ctttctgtgc agcatgttta aggaaacgac tgtcaaacac ccatgtttca tcactaaatg 88500 agaaggcacc catgttgatg gtgtagtcaa acttatcaaa gatctgacca gcgttgtcaa 88560 ataccgagaa tgcaatgcat tgcatcaccg gattagaacc atctgaaaac ataatgcttt 88620 tatctgtcat gccaatatta cgaacatatg agactttctt ctttctactt tcgagcagtt 88680 tttcaatacc atcccaagtt gattcagaga tatcagacag atcaaaaggg cagtcactgg 88740 caaacttatc ttccatctcc aagatctctt gcttagacac tttctgagaa agaaccttga 88800 atcttggcgc acgggattcc catacctctt tcccattgtc taaaatgaag aaatcacgat 88860 aaacacgttt ctcttcattg tatcccatcg ttttaggtga caggtcatgt tcaccttttc 88920 gtaggtctat atccatcatg taagtaatga agatctccaa gtcatcccat gaacggaagt 88980 acaggtcgag atcattaact tcccggttgg taaagagagc cgtgatagcg ccacctgcga 89040 ttataacatc gaggctacga aggatatggt aaatatcctc agagaaaaaa ctttttagta 89100 aacggtattc tcgaagatgc tcattcttct cgtaagtgtg gatcattctg gtctccttta 89160 gtaagttact tttagagtgt accagaaaaa gaaaagcccc gcaagagcgg ggcgaggcaa 89220 aggagaggag atataagaat ttattgttat tagaataaga aaagtggcga agggatttta 89280 ctcgtcgagg gtgtctaacc gtttccacag ccgaaacctt ccttagtgtc cactttgaat 89340 tttagatgcg tggatgggag tcgaacccac aattttcggc ttatgaggcc aacgtgatct 89400 atatatccgt ttcactaaca cgcaattgtt tggcgggacg gggtggattc gaaccaccga 89460 caccatgatc ttcaatcaag tgctctacca aactgagcta ccgacccaat atgtggtggg 89520 caaggagaga ctcgaactct cacgccatag gacgccagaa cctaaatctg gtgcgtctac 89580 caattccgcc acttgccctt atcgatcctt cgggagaatg ccaccctcgg acagttacca 89640 tgatgagcat ttataggcaa tatactcatc aatccttgct ccgttctgat aatcgttacc 89700 gtccgaggac gcattgcgaa cctatcaaca gccgaagact ttgccgtatc gttgtacacc 89760 gagtcaggct tccgctatat tggtgcaagc acagggattc aaaccccgac ctttcgcctt 89820 cgtatgacga agctctattc agttaagcta tgctcgtatt atttaccatg tctccggtat 89880 ttttcacggc gacgtgcttg ttgttcttct ttcgtaagag aatcccaagc aagtttcttt 89940 ctgaccctat ccttttcctt gaactcttct ttggtaaaga atttctgatg gggttttctt 90000 gcagcagaga tattgcacct gagatgactg tatgagatat tattaatatc aaagaacaac 90060 cccttaggat ctgcactgtc gagccagggg ggttttatgt tctatggaaa aaattatctc 90120 gctccatagg agcgccacag tgatggcagt aattggagtc agtctttaca ataaagtccc 90180 ataagagatc ttttaccaat ctaccactcg ctgtgcttgc attcattcct aactgcaacg 90240 ctttcttgtc tttcatcgac tatccttaga tgtctaatta tagaattggt cagtgcggta 90300 ggatttgaac ccacgaccca gagcatccaa ggctcccacg ctaccagact gcgctacgca 90360 ctgaaggtgt agattttaat tatcccaggt ctctacaaaa ctagtatcgc tggctagcta 90420 atatcatgcc ccgttagggt acaattggtt tgatacgtcg aactcatttt gagtgccttc 90480 cggcaattta catcaacata tcaaatatac gaggttagag agaatcgaac tctcggctcc 90540 agcgtgacag gccggtattt tgcccaacta aactataacc ccataatttg gcggaaaggg 90600 ggagtttcga aatcccgacc cctcgcttaa caggcgagcg ctctgcctct gagctaccaa 90660 tccatttaaa tactttatca gtcaaaacaa ccttttgcaa gggatatttc aacccatttc 90720 aatttggcgg gatctgaggg tttgcacctc acctacggtc ctggatgccc gtcattctgc 90780 tccgctggtt gccgtcgcat ttccagcctc attaaactat cgtcccgttg tttggtgggc 90840 cgcgaaggat tcgaaccttc aatccccgag ttaaaagccc ggtgccttat ccagtttagc 90900 tagcaaccca taactgtcct gactgtaatg ttgtcggctt ctcggcagac agtaagcacc 90960 caagagcgca taggcaacaa tacagcttct aattggagga gagcaacaga atcgaactgt 91020 caccgtatcg ctacggtggg accgggttca aaccggagtc tgcaccttgc agcctgctct 91080 ccaagattat tgtctacttg gattttcacc aagacagggt taggcccgta gcgtgtagcg 91140 gcattcctcc cagaaccgtt ccccaactct catggggatg atagatacct acgcgaccct 91200 gatgtattga acatctttag acaatttgga ggaagatgtc agactcgaac tgacacgccc 91260 atttctgggg tactgtctct ttagcaaaga gatcccttac ctgattaggg ttaatcttcc 91320 aattgttctt taatttcttt acgaagatct gctttttctt tcgcacgagt aatagggact 91380 gattgaattt cttctgcaac accacagtta ctaccgtgga gcctacagcg tccaaacact 91440 ttcttgcaac gcaaaagttt ctgcataaat cctccataaa gtggcggtgg aagtaggatt 91500 cgaacctacg gacccctttt gggggcctac acctttccaa ggtgctgtct taaacctctc 91560 gaccattcca ccaaattcgc ggcagatatc gtacaaacga aaatctcgac tagaacacat 91620 gacgtgggaa gatagagata atcacgtatc tgcaaattgg ggtgacctgt gggtatcgct 91680 cccacttcct caacgtcaca ggttgaacat catctgataa atgcttaggc cacgcatgag 91740 tattctcaaa agaaaacact caaacttggc agggagatca ggacttgaac ctgaactacg 91800 gatttcaaag acccgtgtac taaccaatta caccatctcc ctacaatcgg tgagggcgcc 91860 tgaaaccgag ccaggctaag tatcggactg caatcctaag cttattttgt tgccgccatg 91920 cttacttatg accgacaaga tttcccgttg cagcggtaga tcatagtcat tttcaacatc 91980 cggtcgcccc cattatctgg catgaaggtg aggagtcgaa ccccttacga ctggctttgg 92040 agaccagctt gctcccggag caattaagtt acccgcacat tgtttggtgg gcatcagtcc 92100 gattcgaacg aacctcagca agtatgccag tgagctacaa ggtgcgcacc cacttcaccg 92160 ggcgttttcc aattcgcctt agatacccat tatttggtac tcccaccgag gatcgaactc 92220 ggatttccag attgaaagtc tgacggcctg tccatttagc cgataggagc attttttggt 92280 gtggtactct aaacaattct tctgacgata cagatgcctc ttgtttattt cccacattat 92340 ttggagcgtc tagagggaat cgaaccctac tctgcgaggc ttggaaggcc tgcgacacac 92400 ctcgtgctta gacgccttaa attggtggga gtatctggga tcgaaccaga gacctctcga 92460 ttatcggtcg agcgttctac cgctgaacta tactcccatt aattggtggc ccaccctgga 92520 ctcgaaccag gaaccccgaa gggcacggat ttacaatccg ctgcaataac cattctgcca 92580 acgagccaat taaccttgtt tgaactgaac aatatctgtt gtgaatggtt tactcatagg 92640 agtagatttc ttatcatcaa cattagttgt ttcagcttct tcattctctt catcgaagta 92700 atcagaaagc atttgttcac ctttctcaat tacaaatcga gcaatatttt ccctgatatt 92760 gtcctttgtt gtggcacttg tcataagatc tttcaatacc ttatgagcat caggaatcat 92820 agcaatcata ttggtcttaa ggtcaaggat attcttctca agctgaatag cattagactc 92880 ttctttaagg ggtctacctt ttcctctacg acgctttgta agttgttgtt ttactgccat 92940 aataacccca cttattaatg ttatcagatt taaatttatc tgtcaagggc cattttatca 93000 ttttttataa aaatattcaa caacttggag cacggtaggt gaatcgaaca cctgacattc 93060 ggtttgcagc cgaagctgtt gccactccag caaccgtgct tttgggggac ccgattattt 93120 caattcgctc ccacacattc gggtcaagac gtgtcctata gtctttcgac gcttccacag 93180 ctcggagtaa accgtcccgg ctgtcctgtg aatttggcga aggcggcagg attcgaacct 93240 gaagccttag aaatggtgtt ccctcgtgga atcgaaccac gaacaggagc ttagaaggct 93300 cttattatat ccatttaact aagggaacta aaaataccac tatgtatttt tctatgacag 93360 tttgaacaaa caaccacaca tttgcgtatc tcagctttga gtgtctctgt tgaattagaa 93420 tagcctctcg atatattaaa ctctttatcg ctgtctggat gatgaaagtc taaacatgca 93480 tagcatttct cactgcaata agcacacccc tttaaggttt tgtatcttct gaccaacttt 93540 ctgttatgcg aagctatttc tgcatttctc ttccttatag ccccttttct tatggggctg 93600 gatttatagt gggaagagtc tataattctt ttgcattccc tacaacaatt ctgtaggccg 93660 tctctcttag agctattctt accgaacagt tcaagtggtt tacttttcct acagtgagaa 93720 cagactttca tactcactcc aattactcga ttaacgacgg gttagaagcc cgttgagata 93780 cgccctctta aactgatgcg ccctcccgga ctcgaaccgg gaaccctggg agcttaacac 93840 ccatgcctct gccagattgg accaaggacg caaaacattt atgtgctgcg actctctcaa 93900 aacacttgtc gggagaaggt caagaaatat ccgcgaaata cccctatcgc cccaccctat 93960 gcaatgtctg tcgtttcggt ttgcaaccct tgcgacttct attccaaatg gagaaagccc 94020 agccataaat gttttgtgga gcagggtggt ggaatctaac cacctatgta ttctccaccg 94080 cacgtatgta gcggggatat tttcaggtct ggatggacct cgcggttgac aaaccgccta 94140 ccctgcattg gcttctcgaa caggaatcga acctgtaccg tccctatcgt gggaccgctc 94200 taaccaaagt aagctatcga gaaattgttt ggtgctcgca gtaggacttg aacccacgac 94260 cttctcctta caagggagtt gctctaccaa ctgagctata cgagcaagaa atgctgtttc 94320 cgattaacag cctggaggag tcagttagcc atatcttgtg agctaagatc ctatatccag 94380 gatttaagta atcaaagaaa ttttagcttt atggtttaga agtttcaagt ttaaacatta 94440 agctttgaac gataatcttt gaatgttgaa tgttgaagtc tttcgaattc gcgattcgac 94500 aatttcgatc aaaccgcatc attgtgcgga ctgacggaaa catacgttta agtatcatcc 94560 tgtacgatta tgttcggagc agtttaacct ccggccccgg tagaggcaag atgtttctga 94620 cttcgctaac caaaaacagc atttaaaaac tttaccagct atccgcagga attacaagat 94680 gttaatcaag aatccctgca aatattttag attgatcctt caatctctac ttcagtccgt 94740 gcatttgact cggaaagaac aaagtcaacg ttagacttaa agtcttcaat ctctgcttcc 94800 agagaacgaa tgcgatctgc cagaccaagt gggtcaacaa tggaaggagt tcccatgcta 94860 cgaactggcg cttctactac agccaactgt gcagcgtctg gcgctttatc acgttggaca 94920 tatggagcac gagcagcttc aagcttcgcc tcgaattcct gtgtatcacg gttcaggcga 94980 acctgagcat gattatactg agacttcagt ttgccaagca gaagctcttt gaaaacgatg 95040 gtgcgtttac gttcaatcgc ctgagctacg gtcatagact cgccagcgat ctcaactttt 95100 gttacagcgt ttgactgaac aactttcgcc ttcaggtcgt cgcgaacagc cagaagatcc 95160 tgaacaccct ggaagtctgc ctgagcagat ttctcgaagt cctcaacgct ctggatagag 95220 cctgggatct gacggtttgc gtcagtgcct ttcgcgatgt gaatcgtgtt cagcgcttcg 95280 atacgcttct gaatcttttc ctcaaccttg gtcagggtag ccagagcgcg ggttacagac 95340 atcttagtag acatagaatt ctcctctcat gaaatttaaa atttgagtta cttcaaatat 95400 ttgccgacat ccgtgtcggc actacgcatt agtttttgcc agtgttgaca acaacgccct 95460 ggcggttagc atcagctttt gcgatttcca gacgggtttc gcgttcagcc ttcagatcac 95520 cacgcgctgc ttcaagctgt tctgtcagca ttgcaatacg gtcatcctta gccttgctat 95580 tcgcagtaag ttctgcaatt gcaaccttgt gagcagattc cagatttgcc ttaaccgcat 95640 tcagttcgat tgcagcgcta cgtttaacgt cggcaactgc gctttctaca gcttcagcat 95700 tgttctgctg agagatcgcc agctctgcac gaaggtcttc aacaacaccc ggttctacag 95760 ctacaaggcc gcgagctttc aggatagaat tcagaacgga atcttcgttt tccagaactt 95820 tgatcttcag cttggatttt tcttctgcca gtttttcgtt gaactgaact tcaatttgtc 95880 ccagttcctg ctgcttaaac tgaatttcct gactgatctt ttcagaccct tctgccagag 95940 attgcagttc agcgactact ttagtcagac cagtagcggc agtggttact gctttagtgg 96000 cacgttcagt tacggaaatt acagttttag aatcagtcat taagttctcc tttgcgttaa 96060 attaggttta aatactacac ttacagattg tgtttgtcaa gcgaatcttt gattatttct 96120 tcggtggtag ggttgttttc aaaccatgac caataatacc aaagaacaag caggaaagag 96180 atcactgaca tgatgataaa gataacaccg ccactcatcg tacaacgtcc ttaatgcagt 96240 caaaaacttc accaacgacg tctgcggtag gtgatacgat aatctcatca gcggcgtcaa 96300 taacttctgc ggctacatct acaaaaggtt ctgcaacagt tgccgtgaca acaacagcag 96360 taccaacaat atcgccagcc atacgtaaca gggatccgaa catttcgttc tccttttggt 96420 ttagatttga aacgagagca ctttcgtcca tttaagctat cgccctgtgc cactacgcga 96480 gccgggccag caagaacggg agtcgaaccc gtatctctct catttcaaac ttggtggggc 96540 atgaaggatt cgaaacttcg acctggctta agaggccgcc acaccaacca ctgtgttaat 96600 accccgaaaa catgcccgtg tttttaaaga cgtttcacgg aaacgtcatt cccaatgccg 96660 gaggaattac tttttcttct tacccttcgg agctacggtt tcaataacct tagtttcctt 96720 taccttacca gcacgttcac gcttggtctt gcctgtgcgg atgcggtaag aagcagagat 96780 aatctgacca ccttcaatcc gggtttcgga tttatactcg cctttacggc gatcgaaaac 96840 tgatacggtt ttctctacac cgccgagacg cacatcgtgc ggcgcagaat gagtctgagt 96900 agacttcgac tcaaactgga aaggctgttt gatagcatcg atggcggata ctttcttagc 96960 agtatttttc ttagtcataa ttttctcctt tgcattttat ttgggaattt gtcccgttta 97020 tgttcatgag gatactaact caatcagata tcctcgtcaa catttttaat tggtggcccc 97080 cggaggattc gaacctgcct acctctcgat tatgagtcga ttgctcatac ctaatgagct 97140 tgagggcctt atcgttcaga gtggaattga accactgacc ttgtccgtat gaagaacctg 97200 ctctaccaac tgagctactg aacgcttgat gtggtagata ttatagatca cctgtttcat 97260 tgtcaacgtc ttttttacta ttactgcaaa taaaacagaa aatttctctt ttaggaccta 97320 tgtactcctt cccgcagtta gtacaggctg aatgataata cataccccgc agactttcac 97380 caggccagtc tctttcagag aatgcgatgc agtgattaga ggtcaggtcg ttcatcagtg 97440 tatacctctg ggaacaattg tcttgcccta gccttcattt caacaatgat gtcattcagt 97500 ctaagactga ggctatgcat tctttctaaa gtttccatat aatgcctctc agaagtctgg 97560 gtgctcgtca gaagaaatcc cctctccgaa accaataaag ccgtcaaatt catctttcat 97620 cgttttgctc cttttcgttt tgaacgaatg atcgccgctt cagcacgacg ttgttttcga 97680 ttcttaaatt gttcggaaga ttcggagagc gtatttgatt gtgagatctt catcattggg 97740 gtagagatag tataatccac cttcttcacc gaaggaggca acgtatttcc aggcttcaat 97800 tccaaaacca gttgtagaaa aagcgatctc atccgcttca tcagtggctt catccagttc 97860 cctatgattc gattcgtgtt caatatactc tccgttatca gttttgtaaa cgagttttag 97920 tttaaacata gtgtcctacc gtgtaagttg ttaagagtca agttattttg ataactcaat 97980 cttaccagcg gacacctttt ttgtcaatcc atgatacctg agtcgttgac accacgacgg 98040 tattctgcta tggaaagtgc tctgatacgt tctatgaact catcatcggt ctcccattca 98100 cagtcatcat cgtaatattc atcaagacct tcctcaacct caggaaccca agacttcttt 98160 tggtcttcat gaacagatgc cctgttaaaa tcatgtttcg cgactaaatt acgcaccctc 98220 tacctcttcg agatcgattt taccggtatt ggtatttatc cagaccgtct tatctttgct 98280 cgcattcatc tggtgaccac aaccgtaagc gatgatgcag acacccggcc cgtgggctac 98340 aaggtctgct tcgacttctt ttttgcaaac tttgcacgta tccattattg gtccgaacat 98400 ttttctttct cctcttgttg ttgacgttgt ttttcgataa tgacatccat agcggtgtat 98460 ggtttgtttg taccgtgcca ttcaagcggt tttaaagttt ccatagtacc ctcagtaagg 98520 tgggatgtta gaccaatggt cttcatcatc aacacaatcg ctcggagctc caagacagaa 98580 ttctgccaga ctaccgaggt ggtcgttagg gaaaccaaag gaataaacat ctctgcgaat 98640 ggcttcgtct aaatcaaaat ttccgtatgc aggattaaac ttagtgaccc ggatgtcggg 98700 ttctgatttt ggttttattg aaatcgtttt gtgtacatca cgagaagaac tgttcgggca 98760 ataataaaaa tcaccgaact ttccagtacg tattcccatt ttcgttttgc actttgggca 98820 tttcataagc aaacctcaag aagaacccgg ctaaatgccg ggtttgttgt tttacaattg 98880 ggaagctgct cgctcacgga tcgttgtcag gtcttcatcg acaatcagtt tgccgttgta 98940 gaacacacga cgcagttcgt tatcgtcaga ctgtacatct tcaagctgac aattgtcaac 99000 cagtttcagt tcgccattct catcacgaac aaccttcagg aaaccttttg cagatttctt 99060 accgaggtca gtcttaggct ctttgacaac catgatctgc tgaccatcaa tcacagcgcc 99120 agttgctttc acagccatac ccagtgaatc acgggttgtg tactgggtgg taaaggaacc 99180 aacaccgtac acgatattac tggatgcaaa gcctttttct ttcaggcgtt caaagatgtc 99240 ttttgcacga gcaacagtga tggagtcacc gtagatcagc ccaacgtggg tgtccagaac 99300 cttgtagcct ttggagttaa cttcaccacc aaaaatttcc cacaggcaag aaatagcacc 99360 aatggcttcg tggcgaggga gttcatctcc gatactccaa atatcatcct gttcattacg 99420 atcaataaaa taatattttc cattcatctt cacaacttcg gcctctgatg gagaaggatt 99480 ctcatcataa aggcaagtgt aaatggaatc ttcagcttgt tctccagaaa actcaccata 99540 aatacgatat ccggcaatga tgtgctcagg aacacctgag tcaggacgga atacaacacg 99600 accgtcacgt gccatgattt cctgtttcag gatcgctgct gctttggtga taatagccca 99660 gaaatcatag ctgtctgcca cgtaggaaac aaaaccttta gggaaaattt ccgtgatgta 99720 gaaacgcagg aattcaacct cagccaggaa acgtgcttca tccagagtta gttccgggtg 99780 ttcaccttgt aggcgaccga cgataaagcc gatgttcgtg gttgcaacag agtgttcaga 99840 tgcaggaata gaaccagcaa cgaacttgcc tttcatgttg taataacgac gagcatacag 99900 aatcgctggg atagtgtctg tacccattga gttgatcagt tgaccgaact cgctctgtgc 99960 agcatcgtga gtaccagctt caccgcgata ggcgaagcag tggttctgga atgcaacatg 100020 gtcgttgtta tcacaggtct cagcagccca tttttcagac agcttgcgat actgccagaa 100080 cgtcgttgca gttgtgatag ttttccaggt ttctgcggag atcacacttt ccaggaagtt 100140 aggcaaccag taaaaatccg ggtgcgtatt ctggattgta aacattggga cctgaaccgg 100200 agaaagcgtt ccttctggaa gagcacggat ttccagagga agataaccga gatcatgaag 100260 agcctcaaag ccccaggttt ctaccatgcc aatgccgatg ctggagtcgc aaacctcacg 100320 ataatcagca accgcttctt ctttcgggag gttgaagaag ttattgttga acatgtcgat 100380 aaggaaccac ttaataaatc cctgaagtcc agcaaacatg acacgctggt cgttatcggc 100440 gaagtggatg aagtgcttcg cattacgagg ggtcatgtta tcctgaacaa tttcagaacg 100500 tttatcatac atggagatgt gtgaaggttt gtaaaagtca gcgaacagga taggactttc 100560 ttgattaagc atgttttgtt tctcctttgt ttgtttaata gggcgattgt acgcccactt 100620 attcatttgt caattaaaag ttttcggtcc agtcgtggta cgcgtagatt tcatcaacgc 100680 cgccttcgta gataacttct ttaccgaagg aaaagatacc gtgagttacg taaagaataa 100740 cacgttttgc tccttttgcc ttcaatgctt gtgccagggc gatgaatgtg cgaccaccat 100800 cgcagatatc atcgacaata acacactcac gtccttcaac atcaccgaaa acagcagtcc 100860 cggtaatttc atttgtcttc aggtcgcgca cttttccagc ttccaccaga ggaaggcgaa 100920 gtcgatcgga aactttctga gcttttttac gtgctccggc gtcaggggca acgataacaa 100980 catcttttcc ggcaagacct tcatggaatt ccgcaataag agcgtcctga ccacggattt 101040 taacgttgtt aagcaacgcg gcggagacat cgctgtgcgg atcatcgaca atgaccttgt 101100 caaacccaag agagttgacg atatttgcga aaactttgat ggataacgct tcaccaggtt 101160 gcattacgcg gtcctgtcgt gcatatggga tgtacggtag atgcaaagtg aactgtgcag 101220 tatgatgaag gccttcaagg cgagaacatg catccaccaa catggcaaga gccataacat 101280 cagtagagtt tttgattttc gcagtgatgt ctacgaaacc aataccacct tttggggtat 101340 gcgccatgtc aattttaacc tgttcttcac cacctttgaa cgtaaagtga tcgacaggta 101400 ctacaagttt gttcagacga agttctaaac tcatttcata tatcctctat taacaattat 101460 gtaatgtcta ggttttgcat tcccatttga atcctgaaaa ccagaacgta tccttctaat 101520 gtatccaaga gactccatct ttgtcaagaa ctctgatact ttcggttgtg acttctcgct 101580 caacccaaac agatggcaca aagatttctg agatgggtaa aaaacttcat cgccaccatc 101640 tgggtttaga ctcttgaagt aatcatacct ccaccaaagc ttgattaatc tttgcaaatc 101700 ttggggtgag agacggtcat caaaaagcca ctgtgtcgga atggtgacat atgccccatc 101760 tctgatattc acagtgttgt caccaatctt tatctccacc accatctcct gtttattcca 101820 cgataggtat aattagaggc tacaccacta acccaatact gtcaactcta attattccag 101880 attaggaata tctaattatt cccgaacagg aatacaatac taacttatca tttaaactaa 101940 cttatgatct ttaaaaaaca ataaaacata agatctaaaa caagatcttt tactacagag 102000 tataaatact ctatatccta gagtcggtga ctcgatgagt tggattatcg tatgaagaaa 102060 agatgatgtc aagtgttgac atgaactttt taacgtgtag aatctagtta atgttaaagg 102120 agattgctat gttttcaagt aaagaaacaa aaattatcgg tgaaatggtc tgtggtaagc 102180 cacgacggaa accggagcag accgatgaag agaagaccaa gttgatgatg ttacgtgaag 102240 tgtatcatga atgtggtgaa gaccacaatg tgtgcgtggt attaccagat ggtataccag 102300 ttgacaaggt cttcgataac ttttatgctt cgataaagtc gagactagct cgacgtaatg 102360 tgtgtgtaac atatgcaaag gacttgactg tggaacacat cgagaacaac aatgttgtgg 102420 tggatctaag tgaaatccat gtaacgctct agaacgtgtt ctaaggcgtt ttaatggtgt 102480 ggtagtacac ttgggttacc aacccatatt aaattaaata cagggcctcc cagaggctct 102540 gagaggtatt gtggaggatt attttggata tgaagagcat tacccgtgat gactccatct 102600 ataaaggtgc ttatctagct ctgagagaca tcatgaagtc tatggagaaa aagtatggtg 102660 tgaaactgta cttagatagc cgggtagact ggggaaagac atggatggat gcttcagttt 102720 acattcatgg tgataggcat atcgttaact tggtgtgcat gaaacttatt gtgtggcaac 102780 attaccagaa aatcagggat gggattctgt tcgcctaccc ggctgaggat atgaaatgaa 102840 gaaagatatc aggaaacctg tcaaggaaaa gtttgatacc tctgcatttg tgttcacaac 102900 cgatgtgggt gtgattaaag atgctctaca gcgactgaat gaacaggagg cagatcctga 102960 agcggaacca ctgacaaagg atcagatcta ttggatgggt tggtgggagc ttaacatgcc 103020 ggaggttgat cgtcgcggat taacacgggt attgacatgt gctcaggaaa atgctgcact 103080 gggtctgtat aagaaaacta cgaagaggaa gaaaaaatga gcagacttgc aaaactaaac 103140 agaagaaaga aaatgttgaa agaaaagcag aaaaacatca cggctacttt ccaagtatgc 103200 cgagaggcta tgaaggcaaa tcggataaca ccttcgcaga gacagttgat ccgtgatatt 103260 cttcgtcctg tgctccacga ccttgaaggt gaagttcgtg atgttacact tcatattcaa 103320 gaggaacttg taaaaagata tcaggagaat acatgattga ccatgttacg tcagacactc 103380 actggtggca taccaacatc cttggtttcc catcgtgtga taaattccgt aagaatctgt 103440 acggtcaaaa agaagaccgt gaaagtctgt atgccatgaa tgcaggtatg attgaaatct 103500 ggaataagca cgtcaaacca gatgatgtcg tagcacacct tggtgacttc gtgatcgctt 103560 acggtcgcta cgttgagcca cgcactcgtg atattctgga aaagatcaac ggaaagatca 103620 ttcttgttgg tggtaaccat gacaaccgag atacgaaacg tatcttccgt gaattaggtc 103680 atgaagttgt tgattataaa gagattaact tcagcactgg aaaagagaag gtgcatgtgt 103740 gtatgtctca ctatccgttc gcatcgtgga acaaagcaca ccacgggtca gtcatgttgc 103800 acgggcatag ccacggctcc tatacagccc ccggtggacg tattctcgat gtaggttggg 103860 atgttcatgg tcgtcctctg acgatgcgtg aggccgtcct gatgtgcctc aaaaaaccaa 103920 tctacactgc tgaccacgga gaataagatg cataacaaag aacgaaattt catagcacgt 103980 aacacggcga agtctttctt cgctactatt cacattgccg gggattatgc tcaggccgag 104040 aatttgtgtc gccagtgggt tatgcaaggt gcttgtgtgc agattgctcc atgcacctat 104100 gtttacacag gtggtgtcga agatggtatg actgtgcggt tgatgcagta tccacgtttc 104160 cagcgtcagg agcatgagat attatcaatg gctgtcgaac ttggaaaata tcttgctcag 104220 gagatgtgcc agataagctt cagtatcgaa accccttata atacaacata ttatcaggcg 104280 gaaggttatg aaaaaagatc ttgatcttat ccataacgtg gcctttttga ttagcgagct 104340 tgaagaatat gttgacgaac tagatctgag catctatgat gactacagcg aaatgaaatc 104400 agcacaaaaa gaagtgctca aactattgaa aaatctcaga cgaaggagag aacatgaaat 104460 tctgcgtaga cgacatggtt gctaaaaacc tagtatccaa aaagacttac accgacggcc 104520 cgttcgcggg tctgtctgtt ctgaagtata agaacaatgt gttctgggat aacctgtggc 104580 atactgaccc acgtcttctt gaatgccgtg gcatggttgt tgatgcagag gacaacgttg 104640 ttatctggcc tttcactaag attttcaacc gcttcgagaa tggaactgac ttacccctcg 104700 atcagcaggt tgtgtgtatc cgtaaagtaa acggttttat ggcgacagca gctattcata 104760 aaggtaagct tcttgtttca acaacaggga cgcttgactc tgagttctct gatctggcgc 104820 gaaaatatct tgaaaagatg aaattagatc ttgttgcatt tccagaggac tatactttca 104880 tctttgaaat ttgtgacagt agcgaccctc acattgttga ggagaaagaa ggtgcatact 104940 tgatcggtat gcgcgactta gctttaaatg ggaaaatgct tgaagaatat cgtcttgatc 105000 gcatagctga agtgatcggt gcaaaacgtc ctcaatggga tgttgttcca tttggtgatg 105060 ttgttcataa tgttaagcat gtgggacatg agggctacgt tatccgtaat gtcggaacag 105120 atgacgaaaa cagcgaactg cttctgaaaa tcaagtcccc acactacctg gcgaagaagt 105180 tcctgatgcg tggcagccag aataagtggg acatgatctg ggataaccca gaagaggcca 105240 agaagcgtgt tgacgaagag tattatggcc ttattgactg gctgcgctgg gcttgggaaa 105300 aagaggagtg ggcgatgcag gactctcagc atcgtcgcaa gattattgaa aaatactttg 105360 aggataaaaa gtgaaaatat ggcttgatga ccttcgtgac ccaaaagact atggtcatcc 105420 tgatgcttta tggttgaaga actctgaaga tttcatggag ttccttgaag atcgtagtaa 105480 gccatatcgt cgtgtcactg agtggcattt cgataatgat cttggtgaga tctcagacca 105540 cgatgggtat tggtgcttcc ttaatcttga ggagaagatt gtctttggta agatgttgtt 105600 tggtcctgta aaactcttcg tgcatacatc taacccatcg gcaggacaca aatttatgct 105660 tgcaaaagag agcatggcca ggtatggtgt gacgattcta agaaacaatt actgaggagg 105720 caaagtgaaa acactttata ttgtccgtgg agtttcaggc gcaggtaagt caacactagc 105780 acaaactttg tcttctgacg ggtactggcc tgtttgcgaa gctgaccagt atcattacac 105840 tgaagacggt gtttatgact ggaagccaga gaacatgaat aaggcccaca aatggtgcca 105900 agacatggtt cgtgatgcta tggaaatcaa tcttgaaaag atcatcgttt ccaacacaag 105960 cacttctgaa aaagagttgc agccatatct tgtaatggct acgttatatg gttatcaagt 106020 ggtcagtatt gtacttgaaa atcggcatgg taatgactct gtgcataatg tcccacagga 106080 aatccgtgac gcccaagagt ctcgtttacg caactcgttg aaattacaat aaggagaaat 106140 agttgagacg cttaatagtt attagtggtg ctggtttttc tgctgagagt ggtgtccgta 106200 cattccgcac cgatacggac tctgggaagg ccttgtggga tgaatacgat cttgaagagg 106260 tatgtaatat ccacgctttc cgtggtaact tctaccataa aacgcacatg ttttataaca 106320 agcgtcgtgc agagttaccc actgcacacc cgaatgcggc gcatcttcgc gtggctgagt 106380 ggtacaaacg ttatcctgga caagttatca acatgacgac taacgtcgat gatttgttgg 106440 aacgtgcggg tgtccctaaa gaagatactc tgtacataca tggttatctg aaagagatcc 106500 ttgttaaaga tgctttcacc aagaagataa aggttgtcga tattggctac gaccaaattg 106560 atcctgatga ttatgattgg tgtaaaccaa acgtaatttt ctttggtgaa aatgctccgg 106620 cgtatggacc tatgtctgat accctggagt ctttaggaag ccaagatctt gtaattgttg 106680 ttgggtgctc aaacacggta atcaacttca actgggagtt gttccctgcg gttatgcggg 106740 ggaccaaagt tgttgttgtt aatcctgcta ttaggtatga tgaacaaatg atgtatgaga 106800 atgcgggtgt tcttgtatat cgtaccggag ctgttgatgc ctttaataat cccggcctta 106860 tcaagatagt tgagaatcac cttgaaggta agacaccatt gcaaagcaag gagaaataat 106920 gcaacaagta aacagtacac tgtacgccct taataaagat ggttctttcc agtgttggaa 106980 ggtgtttatt gctggtaatc aggtagttgt agagtttggc aaggttggtg gtaagaagca 107040 acaaaaggtt accacctgtg aaccgaagaa cgttggacgt tctaacgaaa ccaccgcaga 107100 acagcaggca ttggctgagg cggtttccaa atgggagaaa caggttcgcc ttggatatcg 107160 tgacgataca agcaagcttg agcaggaaga gaacttctcc ccaatgctgg cccatgatgc 107220 aactaaacgt tcaaaatcaa tagtttatcc tgcatacgtg cagccaaagc tcgatggtgt 107280 acgtgctctg gttactcttg atgcagatgg cttcccacaa ttcaatagcc gtggtaacaa 107340 actgtatcct gtaccgcttg attctgagtt gtctgaacag gttaaatccc tttctgagca 107400 ttcagggttt gacaaattcg atggggagct gtacattcat ggtctgagtc tgcaaaagat 107460 tgtcgctctt gctaagaagt ggcgtacacc agagcagatc gaggaagaga ttgaaaagga 107520 ttatcagtct gacctgaagc gccatcagaa agctattgac aatggggaag acagttggaa 107580 agatttcgat ggtgatgttt actctgtcgc gatcgaacca gttaaagatg ttgatcgtta 107640 tggcggctat tcaagccttg acctagagta ccatatcttt gacattccgt gttcaaataa 107700 accctggatg attaacgatg ggatttcaga ctatacagat aaggagtgtc gatacaaaga 107760 ccttatggac actgaccact tcacctctgt tattaaagca gataaaataa atgtggtcca 107820 agggaatgtc tttgacactg aggatgaggt taagcaatca atcggacatt ttatgcagca 107880 aggctttgag ggtgctatca tccgaaattt caaaggtgtc tatgaatttg gtcagcgatc 107940 ttctgatctc cagaaatgga aacttttcca agacggcgag gctaaagtcc ttgattctgt 108000 ggaagataag aacggtgagg gtgtattact ctgcgaagag gaagatggta cacgtttcaa 108060 ctgtaaaatg aagggaaccc acgcagagag atctcaggaa cgaatgctcc ttctggtggg 108120 taagtttatt aacttcacgt tccaagctag aactgatgat ggtgttcctc agttccctgt 108180 cggccaaagc gttcgtgaac tcgatacatt aacatgggag cctgtatact aatgggattt 108240 tatcgtaaaa aacctgtaga ggttgaagca cataagtttg acgggtcgtc aaccagcgca 108300 gggcagatcc ataattggat ggaaactggt gtgtggaagg attccgaaat ccacactcgt 108360 gattgtggtc gtactgtaga gataaaaacc ccagaggggg tggtcgtagc ctctgctggg 108420 gattatgtaa ttaaaggggt ggctggagaa ttctatcctt gcaaatcaga aattttccat 108480 gcaacatatg acccgctgga agacactgat cgggaacctg ggaactaccc agctaaagca 108540 atccgtaagg gtgatgagat catgttttgc ggaaaggttt ataccgtaac gaatactggt 108600 gcgatggggg aggatgttat cctgactctc ggcgatggtt cccaaatccc tgtgcgccct 108660 gatactcaaa ttatcgtaac aaaggcacag taaaatgatc tggtattggc tagcgctact 108720 aggcgcatca tttgtaacag gaggcggcat ttatgccgct tacagattcc gaaaagataa 108780 gctggatgat ttctttgact gggttgctgg aaaggttaaa cgtctgctga tcatctgggt 108840 atttgttatg ggccttgtta cgctggccct tactgtgcca ttatggcata ctatgacttg 108900 tcagttcgac ggctgggccg cgaatacaga gaccagttat tcatggtaca aatcaacctg 108960 cctgtataaa agcaagacag gggcatggct acctttaggt atcagtcgtg atcaaccgca 109020 aggagatggt gatgcatcaa attaaagaaa atactgtaga ttttgaagcg catatctacg 109080 attctgcgat gaacgacaac tacagatggt caattcgtcc agatcctgat ctgccaggtt 109140 cagttaacct ttcttacaat gagttagctc attatgacaa ccgaggctat gagcagcggg 109200 gtatggtagg tttcgataaa gaaacttggg aaaaaattaa atacgccatc gatggtgttt 109260 ttgaaaaaac aatttaggag acttaatgaa agaagcttat gatactctga atgctatgct 109320 gcgcccaacc tctcttgtta agtatgcgaa acatgttgta gattggaatt ctatcgcagc 109380 ctctgcaaag ggtgaattta ccccattgga aaagcagtgg gagtttgtag gagaggagtt 109440 acaagaaacc gttacagcat taatcgaaaa tgaccgtaag gaagttgttg atggggcgtg 109500 tgacttgttt gttgtggcgt cgtatgctta ttggttgagt aataactatt cgctatcctt 109560 aacctataat cctgatctta agttttctcc tggtaaagct tttgatgctt ttgcgaataa 109620 agattatgaa gaaatgctca aactgagtac ggctcttctg tttagtcttg atattcaatt 109680 ggataagaac atgagtagcg ttctggagtc taacgattct aaatacccga ctgtgaccga 109740 ggtcatgtct ttgcataaag gtcttgaatt ggcagattca cttgaggcag aatgtgcttg 109800 tattgaggag cgtaacaatg gtcgttatga aggtgttcac ttcagtattg ttaaaggtgt 109860 tttgggccaa gaagaccgcg tggtattctt cgacaaaggc ggtaaaatca tgaagccagg 109920 gactttcaaa aaaccaaaca ttattgtttg acaatcgtat cggggtctgt ataatgaccc 109980 catcaagaca aaaggagaaa gaagtggaag aaaatattga ttattctgaa attgttgcct 110040 tggctaaacg ccttaaaatg accatcatga atcgcggggc atcttcccgt catgttatcc 110100 gcttcacgat gaagcgtcgt tggggcggcg taaagaaata cgcttatgaa tgcacactcg 110160 gcacactggt atctcatgtc aaccagatcg agagaatggg cggaaaaatt gtcggcattg 110220 acaattgaag cttgacaaat aaaactgaac ggttatactg accacactaa accaaacaaa 110280 ggagcaatat atgccacgta tgccaaaaat caaaatcgaa ctgatcacct ctcttccgtc 110340 tgacccggtt cagcgtaaac gcctaaaaga tagcgtaact gaagtggttg atctccagcg 110400 tcaaatcgct gatctgaaag accagatcaa agatattcgc tctgtggaga aagaaacgca 110460 taatatctct ccaaaattct tcaatagcct ggtgaagcgc gagtatgatg ttcgcttcga 110520 agccgaaaag aaaactgctg cattagaggc cgaaaaagaa gtcttcaccg aggcagacat 110580 tctgtttggt cgtggaaccc caaatgttgc acagactgaa gccgatgatg gtgctgagga 110640 cactgaataa tgaaatacta ccttaatggt gttggcctat ttgtcttcat ctgcgtcgta 110700 ttcgggtttg gtgttccaac tctggtttct gccaaagata caatcagtgt tattggcggg 110760 tttgccttag tcttcactgc cccggttgtc gtgtggtact ggttgcgtaa ggtcttcatt 110820 ccgaagacaa gcgctgaagg agatcgataa tgttgctaaa tctgaaggcg gcaacttggg 110880 aaaagttgca gcacttggca aagtccaaag gtaagtctgc ggcatcttat gttgcaaaaa 110940 tcgtagatga ccacgttgat gaaaacgtaa agactgagta taaaatcaaa gaggagaaac 111000 aaactaatgc ttaagaatat caaacgcgta gtatttgctg gcctgatcgc cctgggtgca 111060 attggtctga ctggttgtga acgtgcaact gttccggcgg gttatgtggg tgttaaggtt 111120 gacctgtatg gtgatgagaa aggcgttcag cagcaagaag tgggcgttgg taagtattgg 111180 ttaacctgga acgaagagat ctatcagttc ccgacgttca accagttgaa caactacgaa 111240 caaccgttta acttccagac caaagattct atgacggtta ctgcgaagat cggtgttgag 111300 tattacgttg accgctctaa ggttaccaag atcttccaga cctaccgtaa aggcgtccag 111360 gagattaccg atgtcaacat ccgtcagaat atctctgatg cattgatcaa ggaagctggt 111420 acgatggata ttggtacgct ggctggtgat ggtaaatctc agcttctgga ccgagtgacc 111480 aagactctta agcagaaact tgacccggta ggtatcgtta ttgtgaaact gtcttacact 111540 gatgaccttg gttatcctcc tcaggtaact gcgtccatca acgctaagat cgaagcgact 111600 cagaaagcgc tgctgcgtga aaacgaaatc cagcagacta aagctgaagc tcagaaacaa 111660 attgaagcag ctcgcggtga agcagaatcc cagcgactgc aagctcaggg ccaggcagat 111720 gctaaagtag ctctggcaaa aggtgaagca gaatccatcc aactgcgtgg tgatgctctc 111780 cgtaagaacc ctgaaatcat gcaactggaa gcgatcaaca agtgggacgg taaaaccccg 111840 accattatgg gtggcaacgg tgcagtacct ttcgtaaatc tgccagcagg taagtaaagg 111900 ttgacaaaag gcccggtgat tagtatcatc gggtctcaac ttaataaagg agtctcatga 111960 tgagtgttcg cagctatctt tttggagttc tcacaggtgt ggttgtgatg tgtctcttat 112020 taatctcttc cccagtattt gccacagtca acacactttc tttggtggat gaatacaccg 112080 atggaagctc taaagtatgc atctacagcg acggtaatcg cacagaatct gttctgaaag 112140 aaggtgctgg ttcttgtcca agtaagaaaa catttcattg aggcaatgat gcgagtaact 112200 gataaatacg tcttcttctt cacataccga gatatgttca gtaatcacta ccgccaggtt 112260 attcctattc gttgtggtgg ttacgagttt ttcactgtag aacattacat gatgttccag 112320 aaggcaatgc tcttcgatga caaagaaatt gcttcccgca tcgctacggt tgataacccg 112380 aatgaggcca aagctcttgg tcgtcaggta aaatgtttcg acaacagcgt ctgggaagag 112440 aatagaatgg atattgtgac ttcaggcctt gtattgaaaa tgaaggccaa caggtctgtt 112500 ctagaagcgg cgcttgggca tcgagatgca gggcgtaagt ttgtggaagc ctctccttat 112560 gatgccatct ggggtgttaa attaaacgaa tatgatacac gtatcgatga tcctgccaat 112620 tggcgtggtt tgaatcttct cggtgagtgc tgggaacggg ctattgatat tgttgttgct 112680 gcaacgtgga ggtgacttga aattagagat cgaactggtt ccaaagacag cgtggtttac 112740 taatcttcga tctcatctca ccaaagccca gtgggatgtt gtcagaaaga aatgttatgc 112800 aaaagccaat tattgttgtg aaatttgtgg tggtaaaggg actaaacacc ctgttgagtg 112860 tcacgagatt tggtcatatg ccgacagtac cattacctta accggtctga ttgcgctatg 112920 cccctcttgt catgaagtca agcatattgg tttggcaggg atccgtggtc gtggtgaaat 112980 tgccattcgt cactttatga gagtgaatga agtaagccgc gctgtggcag agaaatatgt 113040 taaggaagcg tttgatttgt atcatgaacg aagcaagcgt gaaaagtggg aattggatgt 113100 ccggtatttg gacgagtatt tgagtaaaga ttgagagggc tagtggcata tccgtatgat 113160 aaagattgga aaaacaaagt aacgaaagac tgcgtattag ctttggatct tgaccagaca 113220 tgctttgtgt cagccgccgg tgctgaaaag cgtacaattg aggtcactca tattgagtct 113280 ggaagaacaa agattttccg taacaggact gaattttggg gatcgacaaa gaaagttgtc 113340 ggtggatgga tcaaagacca aaacatgaac atggaggcga aggcaagggc cgaaggccga 113400 gtgtttgtac cgtggggtag ggatgacttc acgattaaag acattcagga accggaacct 113460 gtagaaaact gccttcatat cttgaagaca aagatcaatg ctatctttga acaccttgag 113520 atggaaagca atacaggaat gggtgtactt ggtggtgagg gtaacttccg ccttatgctc 113580 ccagctccag agcgttacaa gggtaatcgt gaggatacat tacgcccact ccttcttcag 113640 gaaacaaggg attatgttac ccggaagtat aacgctaagg tgatcaatgg tgttgaagca 113700 gatgactatc tttctgttct tgcttatatg gggtgggaga attaccagaa gaccgggaag 113760 ttcaactaca tcgtggcatc gtttgataaa gaccagaaag gaaaccctgg gcttatcttc 113820 gatactatgc gcgattcaga agagaagaca tggaagcacc cgatccctat gttgatcgac 113880 gattcgatgg gtgagatctg gatggaaggt aacaaggtca agggatgggg acgtaagttc 113940 ttcggttacc agatgctttg cggtgacagc tcagataaca tcaagccata ccagtgtttt 114000 gatatcgctg gacgtttcgg tgatacggcg gcattcaacc tgatcggaca ccttcaggat 114060 gagaaatcca tgtggcaagc gatcattaac caatataaaa cctggttccc gaacggtgtt 114120 gagtttactt cgtgggacgg cacacaacgg aaaatgagtg caggtcagtg ggcatctatc 114180 atcttccaga tggtctacat gaagcgttct gcgaatgata agacaaccct ttcaagtgag 114240 ttacgccgtg tggggatcgt atgattgata acttaataat gcaggcagtc atgagggatg 114300 ctgaggcgct ggctgttccc agcgtcaagg gtaaattctt agtcgccaca gggttgtggc 114360 gcatggtcga atctggtgat gattgctatg tgattttcac tgatgactat actgatccta 114420 atgttgcatt caccgtattg cttctggatg attgtgagct ggtagaaggt gagaagctgt 114480 tgatgttaac aagcgtcttg ttggatactc aagaattctc acttgttgtc ttcaaggacc 114540 aaaatgactc ggaggtaact gatgaagctg atgtcggttg accagagtct tagtcattgt 114600 gcggtggtta tttgggatga taaggccgaa aagcccgaag caagatacat gatccgtaca 114660 gggtctactt cgagtaaggg caaacggaaa aaggatgtcg tgtatttcga tcatgtgatt 114720 cagcagatcg attacattgt cagtaagatt tgtgagtacg taaggcttca caaaatcgac 114780 acttacgtca tggagtcgtt ggctcttagg tctgtgggta acgccacccg tgacctcgct 114840 ggactgttct actgcattca gatggcactc ttggagcact atatgagcgt agagcaactg 114900 catgatgtcc cccctacctc tgtgaaggct tgtgccagaa accttttacc cgaggcagag 114960 cgtaaatttg ttaaagaaag agttgacaaa aagaccgggg aaaaggtata ctccaactgt 115020 aagattaaga tggaaaaggc acacatggtt agggctgtag attgtgatat gcccggctgg 115080 ttggatggtc ttacactcgc ggctggcaaa gcagattatg ctgatgccta cctgataggg 115140 aaggcgtttc tggagggatt atcgcaaagc gagtaaaatc taaatcatcg aagcccagag 115200 taaggaagaa gccagtagtt gtgccattaa caccggaact ttgggtgaaa gatgcaaagc 115260 agattgctgc tttcagaaat aaattgattc tggagcagca agggttagat cctatactcg 115320 gcgagccact tcgcaagccg tgcttggatc atgaccattt cgaaggtaaa tgcagaggtg 115380 tccttagtca gtgcgtgaat acttttgagg gatatgtcct gaaggcttgg atgaagtacg 115440 tttcagagaa tactcagacg tcgttatcca ccgctcttag aaatttggca gattacttag 115500 agcaagactt cagtggctat ccgcttcacg gcgggtttaa gaacgatatg ttgaagtttt 115560 tgagaagatg caccaacgag aagataattg aaagagctaa ggcggacctt ggcataatta 115620 tccccgaagg tactcagaaa caagacagcc tcttgctata ccttacagag ttcgtcaagc 115680 agacggagga aaaacatgcc aaagaaacca cttaaattct tttacagaaa ttggcgaggt 115740 aagtgcggat atcgtactgt agaagaaccc gtcatgtggt atgggtctac ccagtatcac 115800 aagaactctc aatggtttat tagaggttat gatctcgata aacaagactt tagagatttc 115860 gctgtgaatg atatcattga attcgtccga gaggtgtaat gctacctgta gataaaaaga 115920 ttatagaact tcatgaaagc ggaatgagta accgtgaaat tgctcgcaca ttccttggaa 115980 aagagtcgag agagtcatac atccgtttgg ttcttaagcg tcatagcgca gggtctacgc 116040 ctttaacaaa ggccttagta tcggactata agaaagccaa gatcctgttc ttagatatcg 116100 agactgcacc gctgaagggg catctctgga gtctatggca gaatggaatt gggcttaacc 116160 agatggtttc tgactggtac atgctatctt tcgtagccaa atgggctgac caggacgagg 116220 tcatttatcg cgatatccgt gataattacg ataaggaaag tgatgcatct atccttcaag 116280 acctgtggga cttgcttgat gaagcggatt ttgttgttgg gcataatgtc cgtaagttcg 116340 acattaagaa ggtcaatgct cgtttcctat tgaatggaat ggataagcca tcaaccttcc 116400 gtattatcga taccatgctt atcgccaaag ccctgtttgg attcacctcc aacaagctgg 116460 aatatctgac cgatcgcctg tgtacgaaat acaagaagtc taagcacact aagttcccag 116520 gacacctgct gtgggatgag tgcttgaaag gtaaccccga ggcttgggat gaaatggaag 116580 agtataacaa gttcgacgtt ttatcgaacc aagagttgta cgaaatcttc atgccttggg 116640 attctcgtct gcctaacttc gatctgtatg ttgatggtgt tctggatatg agcgagtgga 116700 tcgaggatgg cttccattac accaaccttg gcaagtaccg acgttaccgt cacaagatca 116760 ccgggcaaca gcgtcgtggg agaacaaacc ttctctcgaa agagaaacga gcgcaactgc 116820 tatcaaatat tttggtttaa ctttaagggc ttcggccctt tgcaaaggag attctatggg 116880 aagagaaatt gttgttaaag ttcctgatgc cgcagatgat gagtggctgc gagagcagat 116940 cgaatcctta cgtgtaagga tcgaggctgt tgtagaggtt gaggataacg aagaaagctt 117000 taataagtta ggggcttgcc ttgacatcat tgatgcactt caacagtata cggggtacta 117060 atggatatta ttgttctgaa tgctccccca cagagcggta aagatgagat ttctgcgtac 117120 ctttgtaaag gtaacccaaa catcagccac gaagaggtaa aggaactcct ttttgaggtt 117180 gctattcgtt cagcgggaat ttcccgtgag ttgtgggatg caatgtatac ccgtcggtat 117240 aaagagatcc caagcccata cctgatgatt gatggtgtga atgtgtcgcc acgtcagtgg 117300 atgatccatt gctccgaaaa ggtaatcaag ccattgttcg gcaagtcagc attcggtaaa 117360 gctgctgtgg aaaagttgaa gcagacctat gcaaatgacg aggtgattgt attctcagat 117420 ggtggctttg ctgaggaaat caaagagttg tccgattatg catactcgac tggtggtgaa 117480 ttcttccttg cacgtatcca ccgaaaaggt tatgattggg ggaatgacag tcgtaactgg 117540 ttataccttg acggcatccg aggtcatgaa cgtgacttcg ataacaaaga gggcggtatg 117600 aacgactgtg cagaagagat ccttgagtgg gcaagaacaa ttagctatgg agaagacgat 117660 gcgtaaaccg atgaatatag gtattgatgt cgacctaact tttgtggatt ctggtactcc 117720 ttggcttcat tggttggaac tgatgtatgg cgttaaggcc gactgtagtt tgccaccccc 117780 taacccacag gggaagactt actataatct ttctaaatat tttccacccg cgaaggttaa 117840 tcaattacct ccctatgagt tctgggaaga tccttatttg tacgataggc tgaaaccacg 117900 ccctggcgct gttgaagcag tggccgcatt tgctgaagct ggtcacttca accaatttgt 117960 atcacactgc aaaaagggtc acttttcgtc taaggtacgc ttcttgaaac gtgagacaga 118020 agagttcttc agccttgagc cgggttctgg tcatggtttt tatgcgacga agaacaaagc 118080 aggtcttaag cttgacgtca ttattgatga tcgcaatgaa ttcctgaatc agttcggaga 118140 tgacgtactt aagattaagt tctggactcc gtatgaccaa tctgaggagt tgaaagtctc 118200 gattgacctt gagacatccg actggagtca tattcaggac tttattctgg acctctcctg 118260 atgaaaagga atagatgcga gggaggtgat ttcatcgtcc gtcagggtaa gtggtacgaa 118320 gtattcgatg agaaggataa tttcgtgtac tcattcaaag cgacaagcga catgtgtaag 118380 aatgtgctta accgctactt ggtgttcaag gcagaccttg atccaaatgt taactacaaa 118440 attaagaggg ttggaaaatg acaaaggatg aaatggcgga acacatccgt acacaagcaa 118500 cggctcgtgt gaatcgtgtt attgaaggta tgttcccagg tacaggactg actgcggata 118560 tcatgggtat tgatgcggat tttaataaag gtctttttga tgacgtctat ctgaacttat 118620 tctctctccg cgagctggaa gagattatta ccccccagat caaatacaaa gaccgtcttg 118680 ctgaacttga cctgttagtt gaaactgccg tcgccgcccg tatggctgaa aaccaagaca 118740 agattattga gaaattagga gcaatgagtg agtaatttga tttccgtaaa aattgtagct 118800 gacagcattt ctccttcagg cattcgaatc ataaccttcg aacttgaata cccacgaata 118860 atccatagtg agctgatgac tcaccgactg ttaagtcgaa atgcgatgag cagtcgtgct 118920 attccgatta agaaaatgat cgagcaggtt cagcaaaatc ctgcaatgcc tgtgaagttt 118980 ggtaagaacc aacctggaat gcaggatgcc ggggagcact cagcacagct tggtgatggg 119040 tactcggcag aagagtggtg gaaactcgca ggacttagtg cagcccggtt tgcagcagaa 119100 tttgcagatg cgggttatca caagcagatt gcaaaccgcc ttctggaacc ataccaaaga 119160 atgaagacag ttgtcaccgc tacagactgg aataacttct tctggttgcg tgttgacccg 119220 gatgctgatc ctacgatcta tgaactagct aaggcaatga aagaggctag cgataattct 119280 atcccagacc ctcttgaacc gggacagtgg catacaccat acgttgacca cgtttatggc 119340 tttcaagata tcgacgacaa agagtgtgca gtatttgaag gctattgtgt tcttgacgaa 119400 gagaacaagc ctgtaatgtt gactctggaa gaggctttgt ctgtttccgc atcttgttgt 119460 gcccaggtat cttatcgtgt tctgaatacg agcaaagaaa aggccttgga tatctacgag 119520 aagttgatca gtggtaacaa ggttcatgcc tcaccattcg aacatcaggc cacacccatg 119580 acagaataca gggaaattga gaactctgat tatttaacta tcgggcatat taactttccc 119640 cgtgatccaa gctcttggga agaaggtatc acacacgcag atcgtcaagg gcaactttgg 119700 tccggtaacc tgcgtggttg gcgacaacat cgccagttag tgcctgacaa tgcaatttca 119760 ggttgacaaa gatatcgtta attcgtatct tagaagcata ttaattaggg gcgattttgc 119820 cccttgtcag gcagaatgga gattacatga gtaaagagaa acgcaagcca ccacaacata 119880 tttcggtcac cattgacttc ctgagaacgg tcccaggatt tgatgttcag aaagataatg 119940 acctccgcgc tgccttatac gcactcggtt ttcaggttac cgataaagat gggaatccta 120000 aacacgtaac tgtgttccaa aacaaaaatg taagatgtgc caatatgcca tcgacgtatc 120060 gtaagacaat gatttttgtc ggagaaatgc gacctgatta taaatacgcg aagatataca 120120 acggtgttga aatccttgat gtgggggttt attcaggcag tgatatggaa tttgttttag 120180 atcttcctta cgacatccct gtaactgaaa aagttaacac ccgcaagtat accaagcgag 120240 gggatcgacc agagacattt gaaatcactt tcgatattga agacgaagct cgtctgggcg 120300 atgtatttgg cctggaggac gaatgagtaa agaaaaaacg aaatggaaag accgtggctt 120360 cgatgataag catcattatg ccgggtggct ctactttaac gatttaaccg atgacagtaa 120420 aatgtacgac gatgtttact atgatgagtt ttctggtaaa atagttaaca tcgttgcgcc 120480 agatcaaaac gagaaagacg atcaggttgt tgacgaggca gatgagtttt tgtctcaatt 120540 tgaagaagaa taaggggaaa gtttgatcaa tacagttgtg aagagtgatg gcagtgtggt 120600 tccatttgaa ccagaacgtc taaacaaggc cgctatcttt ggtgatgacg gtaatggtaa 120660 ctggtcgtat atctcaatgg atgcatataa gcgactgtat gacggctgca ccactcgtga 120720 agttaaccag gcattgatcg acgcctgtgt gagtcgtaaa gacgaagccc attcacggat 120780 ggctgggcgc gtcctgattg gacaaatcta caaggaagct tttggcggat ttaagaaaat 120840 cccaagcctt accgagtttt accaggacat ggtgatgcgt gggtactggg aagaaatggg 120900 ctatactgga cctgagctgt taaactttga tcaagtcatt gaccacagta aggacctgag 120960 ttatgggtat gcggttctga aacagttccg ggataagtat ggtatcaaag ataacatcaa 121020 tgatatcctg ttcgaatccc cacagatgat gttcatgggt attgctatgg ctgttatgaa 121080 gaatatgcca ttatcccgta ggaagaatga cgtcatcaga ctgtatacgt atctctctga 121140 tcttaaaatc aatgcaccaa cgccgtacct gaatgggttg cgtactggta aaactggata 121200 tgcatcctgt tgcattatca aagcagacga tacagctaaa agtattggtg ttgcccgtga 121260 agtggcgtac actatgacgg tagcacaggc agggatcggt tattacctgt cctcccgctc 121320 tatcggcgat ggtgttcgtg acaatacgat caaacacatg ggtaaactcc cgtattaccg 121380 tggaattgat gttggtgtta aggaaaatcg tcaacaatcc cgtggtggtt ctgcaacggt 121440 gtctttcctt gcgttagacc cgcaagttga agaactgatg cgcctgcgta atccgatgac 121500 ggttacctca aagcgtatca acacgatgga ctattcaatt ggtgtcaatc actcgttcat 121560 gaatcgcgta gctaagaatc tggactggat gttggtgtca tataaggatg ctcctcagtt 121620 acatgagggt atgttccgaa tgacaatgca ggagtttgat gctgaggttg cccgtgtagc 121680 agcagatact aagattccaa agacttgggt gaaggctcgt gatctggcaa tggaactgat 121740 cactcaacgt gctgaaactg gtcgtcttta tgtttactgg cctgacgaaa tgaaccgtca 121800 tacgccattc cttgagacaa tttactcatc taacttgtgt caagaaatct gtctgccaac 121860 aaaagggtat acagatatgc gcaatatttt caacccgacc atcgatgatg gtgaagttgc 121920 attgtgcttt atcgcctctc tggttgctgg tcgtgtttcc gaagaagaat acgaggatgt 121980 tgcttactac accgtcctga tgatcgacaa cgttatggat atcatggatt atccgtatga 122040 gaacatgaag tacacagccg aatctcgtcg ttcgattggt gttggcctga ccaaccttgc 122100 acactacatc gcgaaacaca aagtcgcgta tggttctcct gagagcaagc agttggttca 122160 cgatctggca gaactgcata gcttcagtct gcataaggca agtctgcgac tggctaaaga 122220 gcgtggtgtt gctccgtgga tgaataagac taagtatccg cagggttggt tgcctatcga 122280 tacctataat aaggcggttg atagtgtcgt gaagaatccg agcctgaagc aggactggga 122340 aactttgcgc caggaaatca tcgaaaatgg tggtatccgt aacagtgtct tggaagctta 122400 tatgccgaac gaaagttcat cattagctac caacacaaca aatggcctgt atccggtacg 122460 tgaccatgtg atcttcaaga aatctcctca aggctctgtg ctgtttatcg tgcccgagta 122520 tgaagagctg aaggaatatt acacgtcggc ttgggatatc gatacgaatg atttgattga 122580 tatctatgca atcattcaga agttcgcagg ccaggcaatt agtgcggatc tttacatcga 122640 ctatacccag ttgccggatg gtaagatttc catgaaacaa caacttgggt atctgattcg 122700 cgccacgaag atgggtatga agacatggta ttacctaaac tccaaagttg gggctggaga 122760 ctccctcact gaggaacttc atgctaaagc aaaagctgag gaagagacaa gagctgttgc 122820 accacttatc gccggggata ctgaagatcc ttattgcgaa agttgttctt tataagttgt 122880 aggggcttcg gccccgtttt tgaggagaga aaatggcagt ttttaacgta gaaaacaccg 122940 cacataagac cggggactac ccactgttcc ttggtcaaca gatggggatg tatgactcca 123000 tcaataaaaa gtatccgcaa ctgtttgacc tgtataaaaa gcagaaagaa caggactggt 123060 cagaagatga agttgaactg agccagtcta tcactgactt tgctacttgc agcaaatcga 123120 cttacgacgt catggtgcag accctgatgt ggcaatggga agctgatagt gttgcagcac 123180 agtctatcat ctgtctgttt gcaccgttta tcacgaatag tgaactgttc gccatgatga 123240 tgaagcaatc agagattgaa gtcctacatg ctctgacgta ttctgatatt gttcgtcaat 123300 gtctgcctaa ttctcgccag atcattgaag atattcagaa caaccaggcc gtccttgaac 123360 gctctggcgt cattgtcaaa ttcatgcgtg aattagagat cctcggtgct cgataccgta 123420 ttgacccgga ctctgttgac aaagaggaaa tccgtcgagg aatcctgaga gcgatgttct 123480 ccctgttggg gctggaaggt attgaattca tctctagctt tgcctgtacg ttcgctcttg 123540 cagaacaggg tgtgtttgtc caggtggggc agctagtaca gaaaattatg ttggatgaga 123600 tgctgcatac caagatggat ttcggagtta tcgatatcct tctgaaagac ccggtatgga 123660 aggccagttt tatcgcaatc aaacacgagc tgaaagcaat cctggatgaa gttcgtacca 123720 atgaatatgg ttggggcgat tatctcttca gtgaaggccg tgcgatcatc gggttgaacg 123780 ctccattgct gaaagattgg actgactgga actgtgctcc gatctacgat tactacggca 123840 ttgaaaaaga tttcgtagca ccaaaacgtg atcctctccc gttcatggat gtttggatga 123900 acccttccaa gcaacagaat gcgaatcagg aacaaacaaa cactgattat cgtcttaatg 123960 cgacagtcaa tgacgctgaa gatgaagtct gggattttta aggagtaata atggatagcg 124020 ccaattttga atctgtagta tacgatccgt ccaagctggt agttactttt ggaggcgagc 124080 gtgtggtagg cttctcaagt gatatgaaaa tttccatttc ccgtcgattg cacggagtag 124140 ctaaggctaa aatctattta caggctacca gcccttgggt attaaagctt aaacaggcgc 124200 taggccatcc tgcaagggtt gaggcagcgt atcccgtttt tggcagtata tcagaatcca 124260 tgcgtttcgt tggggacttg gtagttaaag ggtatgatgt tgactacaca tcagaaatcc 124320 cagtattcac attccttctt gaatcggaga aacaatgaat ctgaagaatt caaccttcac 124380 catttatggt aaggataact gctcacactg cgtccgtgcg aaggagtttg ccattgcaaa 124440 tgggatcgag tatatctatc tgacactcgg aaagaattac accaaggaag agctggtaga 124500 gcaatgcgcc ccggttatcc ctcgcaccgt cccgcagatt ttccgtgaga cggactcctc 124560 aacggagtac attggtggcg cggatgactt cattgctttt gtgcaaaaac atatgaaatc 124620 ctgttgacat agcaaccttc tgtctgtatg atttatgtaa tcctgccgag aaatctgtcc 124680 ggcaggaaat ttagaggaga attcgaatga gtaagaaagc actgcgtaag gcatatacca 124740 aggaactggc tctggaactg cgtggcaaaa agccgaagaa taaacgctct tctgatgaag 124800 aacttcagca acttgcagca gacgctgccg ctcgcggggg ttactaatgt caaaaaaggc 124860 cgcagttgta accactgact tacgaccttc tctggcaaag gagtttgttt ctctggtgtg 124920 ggaccgactg atcggggatt ttgctactgg attgcaggtg caggttgaaa gtctccagaa 124980 catggtgaag ggagagaaag acgtctattt tgccaaggaa ataaaggaga aaaaagaacg 125040 ccttcgtaaa actctctcta cagaggttca acagaaagtg tttgataaat tggtctgcca 125100 actggcagag gctttgacag aagaagagct gagatacgcg atcttccaag agaagattac 125160 gatcaagatt catggggtag cctcccagct cgaagcggct tttgaagagg cggtgggaga 125220 ggcctaacct gaaaaaggag gtcttttgaa acttacgctg gaacaactca acaaaatctt 125280 tcctaatgga gcgaaggctg gcagaaatgc caagtttatt ggtcctttga acgatttgtt 125340 tgagaagggt ggtattaata ctgtcaaccg cattgccggt ttcctctccc aaatcggggt 125400 ggagtccgca gagttccttt ataccagaga gcttggaaac aatgcctact ttaataagta 125460 tgataccgga ccaattgcaa agcgacttgg caatacacca gaaaaggatg gtgacggagc 125520 taagtacaag ggacgtggtc tgatccaagt caccgggctt gcaaactaca aagcttgtgg 125580 taaagcctta gggttggatc tcgtcaatca ccctgaatta cttgaacagc cgaaatatgc 125640 agttgacagc gctggttggt actggaacat gagaaacatc aacgccgctt gcgatgctga 125700 tgatatcacc aaaatcacca agctggtaaa tggcgggact aaccacctcg cagaaagaac 125760 cgcatactac aaaaaggcaa aatctgttct aacctcttaa ggagaaccac atgggaagaa 125820 gcaaagaggc tcgtgcaacc aaactcagcg ttcgccagca acaacgtgct gagagacaag 125880 ccaagcacca ccctaaattc gatgaggaaa ggaatagcgc tccaccgctg actcctctga 125940 atgacaagca gcaagattac cttcacaagt tgcaaacttg caatattgtt atcgcaaaag 126000 gtatcttcgg tacaggtaaa acttacctgg catcggccta cgctgctgat ctgctccgta 126060 agaatgaact cgacaagatc attgtcgctc gcccttatgt gcagacgggt aaaacctccg 126120 gcttcaaacc gggaacatcg ttggaaaaac tcttcccgta tgttcgtaac atgttagaca 126180 ccatccgtaa acgtatgggc gacggtgcct attacaatgc gcttaaagat ggtctgaatg 126240 ggcgtattga agttcaggaa ttggaaagca tccgtggtcg ttcattcgat gaaagaagct 126300 atctcctgat cgacgaagcc cagcagagta ccccagagga aatgttgagt atcatcacac 126360 gtatctctga caactgtaca ctcgtggtca tgggggatgc ctctcagaaa gatatccacg 126420 gaatctccgg tctggaatgg gtggaagatt tcctgagccg gaacgggatc gcgggtgtgg 126480 gtattgtaaa cttcgacaac ccagatgatg acatcgtccg tggtggtatg gttcgtgaca 126540 ttgccaaggc gttaatcgcc gaccgtgcag aaggacgcta tactccactg gcttcgtaac 126600 ggaggattat ggcttattat acaggcgtgg ggtcgaggga gacccctcct gaggttatca 126660 gcatcatgga agatgctggt ttccgccttg caaggtgcgg attcaccttg agaagtggaa 126720 aagcgggtgg cgcagatgaa gcattccagg tcggaatgca aaaatattac gaatctcttg 126780 acaatgggaa gcaagaagag tatcgtacac atttggcgga gatctatatc ccctgggatg 126840 gatttgcatc tgacaatgac aatctctggg atttctggga ttatccttta gattatcttg 126900 attatctgat tcccgaccaa aaggttgtac gtgaggcact agttgaggag attcatccta 126960 attttgaagc tcttaaaaga aaaagaggag cttttgcgct ccattctcgt aatgtgcatc 127020 aagtcttggg ggccaatatc ctcgatccac gtccctctgc attttgtttg tactatgcca 127080 aagaagatag gaacggaaat cctaagggag gtactgcaac cgcagttaat ttagccagaa 127140 agtacggagt tcgggttctt aacctgaaca cacctgataa actagccttg ttggagaggt 127200 tcttaagatc cttggaggaa aaacgtggca tccagatttc gcgataagct taataattct 127260 tattgtctcg ttaaagttga tgggcagggc tggtcagttg gtaaaatcgg taacaaagtg 127320 attttcatta cttacaagga tggcgggatg aaaaacatct gtaacacaga cgatactgat 127380 ttattcagat acttcctgga atccattgag taccaaagta agagagagtt attcgttggt 127440 gacaaggtca acgttgacaa gttcggaccg tactatgtgg tagatatcgg tcaccgtgag 127500 aaagacggga gtattaagta ccttatagct cgataggagg agtatgacag ttagtattca 127560 tgggattctt tcccatcgga gactgatgga actgaagaat tgtggagtcg tcgagcctga 127620 atttttcgag tccgaggtga caaagtatta caatctctat ctaaaggttg tggctgaatc 127680 actttataga atgaatgacg ggttctttac ccggatgatt tatagccgtt ccgctgccga 127740 gcgggatgcc tcttggatgt tcccggatcg tcgtgacctg ttggaacatt tgatttacct 127800 agatggaaaa tctcagtacg tgagtttgac caaagaagag cttaaccact ttacgctgtt 127860 gcatcaagcg gcagtagcct cagaacgcgc caagagggta ctcctgtgct ttaagtacag 127920 cgaccaagtc cttgtggatg atgattcagg gttcaatata gactggttgt tacggaatgc 127980 atatacatta cgacaactga ttgtagacgc gaatggggag acacaagatg cagaataacg 128040 acaaaaagaa ttactttggc tttggcggtg gttttggtgg ggaaggttct ttctgctatc 128100 caatgccctc tcatgagcat gtgatctata ttcatgattt ggattatatg gaagatcatt 128160 tcaataaatt gcaacaaata cgtcaagcca acccagacga tatggtgcgt gttatcatca 128220 acacttacgg tggacgtgta gatatcgcaa tggcttatgt tagtgcgatg cgcgagagtc 128280 aagcaactgt agttacccat gcagaggggc aggtgtgttc tgctggaaca atcttatggc 128340 tggcttctaa agagcgaact gtcgccccga tgacggaatt tatgttccat aactaccagg 128400 gcggggcatt tggtgatggg gctaatattt atacccaggt gctgttctat aaacaacact 128460 tcgatcgctt aatcgattat ttctacaaag gtgtattgac cgacggggag atcaacacaa 128520 tcaaaggtgg cgggcaggtg tggctggatg aagttgagat cacgaaacga acccgcgcag 128580 tgattttgga tgataaaaat atcgaaagga tgaaatccgg taaaaatccg atcgtaaccc 128640 ctgttggtgt gaaagatacc cagaaagagg acactgttac tggagatcct gaccgcagtg 128700 ttgtcctgaa ggtacatgtc gatggtgaga ctttctcgtt ggatgtgaga aacctgaagg 128760 cctctgattt tgatatcttc aacattgatg agctgcaaag catcctgtca caggttgggg 128820 ctattgcaca aggggaagaa aaggcactgg agattacctc tcgtgatcgc caagcactaa 128880 tcgaagctct cctgaccgca ggtgaagtta tcatcgatac ctttgggaat gccgagtaat 128940 gagtgctcct ctgaagaaaa agggggaacg tagggaccat gacgtatatg aaacccctga 129000 atgggccgta caggcccttt tggatgttat ccctattaac ccctcatgga catacctgga 129060 accttgtaga gcgtctggga ggttctataa tcacatgcct ctcggttcag cttgggggaa 129120 attcgtgaag gtgtggatta tctcaatacc gattacccaa atcatgttga ttgcatcatc 129180 accaacccgc catattcatt ggcccaagag tttgtgacaa aagcgcttga cgatgcagat 129240 gtcgtgatta tgcttttgcg gttagggttc cttgagagta tggcgagatg ggagttttgg 129300 aaacaaaacc ctttagatca ccttattatt ctgtccaaga ggccctcttt taccgacgat 129360 ggaaaaacag atggttctgg gtatggttat tttatatggg acaaacatgg gaggttagga 129420 cttgaaaagc cgatctactg ggcacagcca gatggaagcc attaaaagat acctcagatt 129480 agagggtgca actgtttatt ggagaaagtt ggaaggggat ctaaccagaa cagagcgccg 129540 tcacaacact ttgttttctg gtaaggtggc tggagcatta aacaggaaga ctgggtatag 129600 gataatccag ttgcaaggtc ttcattacag agagcatgtt gtggtctttt tcctgcatca 129660 cggaagatgg cccgaaagta tactggacca taagaacggt aacaaacttg acaaccatcc 129720 aagcaactta agggaaagcg accattcaaa aaatgcacag aactcaaaaa cttcaactag 129780 aaacacctct ggtgtgcgtg gtgtaagttt caataagtta cgcaagaaat ggaaggtcaa 129840 ggttaccctt gagggggttg attatcatgg tgggtggttt gataaatttg aggatgcaaa 129900 atcaaaagct atttctatgc gtaaagaatt gcacaaggag aacttgagag atgatgagtg 129960 ccgcaagcaa gatgcggggg atcgcagaaa tcgcaaacgc agcaatcccc cccgagatga 130020 accagttgta cgacaacatg gtggagggga tccaccaatg tgccaagaag ggacttttgg 130080 ggatggggat ggtgatagat cttccggatc acctgcttga ttatttgcct catattattg 130140 ctgatcttcg tggtggaggt ttcgaggttg atgtcgtaga agttgaaccc tctatgcaag 130200 gcattagagc acgattgtat attacatggt aaacccgctt cggcgggttt tttagttttt 130260 gtacttgact tcctgcacag cttcaattat gcttctcgta ttagaggaga ttgctatgaa 130320 attctacatt tatcaccgtc ctatgcatac catcaaattc aaagagtaca tgggcgatct 130380 gatccatgtt tcttgtgaag agaaagattt tagcccggat ggggagcaat ggaaaattaa 130440 acgttgcaat cgtcctgagg ccgtgtataa tcgattgaac aaaatgctag cttctggtgg 130500 cgtcccttca gatggtattt atccactatc cgacaaacgc tcacttaagg atctggtttc 130560 ttatatgaat acttggggga gacacaatga ttaataaaat ctataccgtt gttagagatc 130620 tgtgcagtga agttgtggga acatcttcta ctgttggaca aattgtaaca gcagtcgtag 130680 caatacctgc tgggacagag atggctattt attccgagga taagttgtgc gggactgcac 130740 gcactagtcg ggatgtctac ttaaccacgg gcggaggatc aagaacttta cactttggta 130800 aggttgttga tcgtacattc gtcgtgcgta ttggtggtac agtgtacgaa ggtaacgatg 130860 tgtataccgc agaagagctg gagattactg aatgaatctt tacgcaaagc ttactaaccc 130920 gaatgcgggt tggccttatg atgagaaacg agcaaaagag tttttgaaaa ctcatgatga 130980 ggaagaaatt ctctctgtgc ttgaagttgc tattggtcgt agcagcacag ccataactct 131040 caatgagcac ggaaacggct ggaacagtgt tcagtttaca tttttcgttg aaggtgaaaa 131100 tggtcttgaa gagtacgata tcttcatgaa taaaaacaat cttccccaaa tttataaaac 131160 ttacgtgata tggtgatact atgaaagtaa ctgcatttgt gaaatatgat ctgtatccgt 131220 attacactgt tgttttgggt gacctgcaag aaaattttga tgtgaaaacg gcatctggca 131280 catacaatcg cgaaaaggtc ctccatgtga ggccgtcaca tgagatagat ggtcatagga 131340 atacccttat ttccattaaa aaagaccacg atcttctttt acggaaatta aaggttgact 131400 tgttgaagaa gaacggtata cacttcatca acacagacaa tttctaagga gaaaagatga 131460 aagtatatct ggtaggtggc gctgttcgtg atggtctgct gggtcgtcca gttcatgacc 131520 gtgattacgt ggttgtgggt gcaacacacg aagagatgat tgaaaaaggt ttcacccagg 131580 ttggcgctgc tttcccggtg tacttgcatc ctgaaaccaa agaagaatac gcactggccc 131640 gtactgagcg caaaacgggt gagggccata ctggctttga gaccttcttc agcccggatg 131700 taactctgga agaggattta tcgcgtcgtg acctgacgat caatgcgatg gctaaagaca 131760 tggagacagg atttatcatt gacccgttca atggtatgca tgacctgtcg aatatgattc 131820 ttcgtcatac tacgtcggcg ttcatggatg acccgctgcg tattctgcgt cttttccgtc 131880 ttaagtcgca gttgggtgag agttggtctg ttgatcatga aacatacaca cttatgttta 131940 ataatcgtca ccgtcttgcg gagattagcc ctgagcggaa atggaaagaa atggaaaagg 132000 ccttaaattc caaaaacttc aataattacg cctaccacat gtcgattatg ggtgaacttc 132060 cagaactgga tgccctacgt ggagtagagc agccaccaga acatcaccct gagggagacg 132120 ctttcattca tacgttgatg tgtctgcaac aggccgataa aaccttttgc tctcctcagg 132180 tgaaatttgc ggtgctgtgt catgactttg gaaaggcgat cactttccgt aagtacggta 132240 atctcctcgg tcatgaagag gctggtcttg atcctgtgcg gacgctgtgc agtcgaattc 132300 gagttcctaa cgaattcagg gatattgcac tgtacgtgac agagcaccat actcgtgtgc 132360 attgcatttt gggccgtggg aataataaag gaatcaagcc acgttccatg atgaagcttt 132420 tcgaagccgc aggtaacgtg gctagtcaga agacacagga taaggtgttt gccttagcag 132480 acgcttgttt ctgcgatgcc cgtggtcgtg gtgccaccca cgcagacaag gaatacccgc 132540 aaggaaaaat tctccttgat gctttcgagg cggttgtaaa tacggacagc aaggcggtat 132600 cttccgcaat gctagagaaa ggcaaaagcg gtaaggagat cggtgaggcg atccgtgttg 132660 cacgtatcga tgcaatccgt aatgttctta aggagagacc atgaaacttg taagtcacga 132720 agatttcaac ttgtggtgga taagacgctc tccaaagaat actatagacg cgaaggcaga 132780 gtatgctcga cttgtggcga gatgtgatta cccggcttgg gaattcctta agttcttgga 132840 aaaagaggcg aacaacttta ggaccagaaa tgaagggaaa aggaaatttc ttgtgtggaa 132900 aaatggagag cttcctttcc gcatagagaa ggtggaaatc ttcgatataa ctgagtatgg 132960 gactgatcac gcaatcagct tcaaaggaat ttcttgggct actctgtttg agagaacgct 133020 gctcaaccat gcgttggcaa gacttttcaa cctagcagat aggctcacgg aaaaagatga 133080 aaaactgctt gaacttgaat ctttcaaaca gaccagagat gaacttgggg attggctgga 133140 ggcgcagaac aatgtctaag gacaaagaag agtacaccta cgagaaacat catttctttc 133200 tggacaaaca tgcagggaag caagtttgtg catggtgcgg tttagtagcc ctgcgtaaca 133260 aggccacaga ctggtgtatc gaaaaaggtt gtaattatcg cttgcatcca agctacaagg 133320 gtgctatgtt taaatacaca gagttcttca aaaaaggata gaaaaatgaa ttatcttgat 133380 gacgttgtac tccctgtatg gagatttatc tttaataacg cagccttgct ggttgtcgtt 133440 ctaagtgtct tggctggatt gtgtgttggt ctcgtttatc gtgcagagga cgacacagta 133500 tgggataaat atggaattcc agcgttaata gctgttatgt gcggtttatt ccttccggta 133560 atcatagggc ttggggttat gcttcttccc gcatttatat tccttgccat aactgcggcc 133620 ataggattgg ggatgtttct tctggttaag tttgtgaagg aaaggaaagg gaaatgattt 133680 ttgccattat ttatattgtt ttcggtatca tcacagcagt ggcgataatt tatcacatcc 133740 ttcgtgaaca agatttactg agggtcgaag atattttaat ttccctgatc tgtggtgttt 133800 tttggtggtt agctatttta tgtgccattt gtggttgggt agggaagcat ctgaatagta 133860 ggacagttgt gtacaggaga aagaaataat gaagacacgt atgtattgcg tagtaaatca 133920 atatattgca ggtatccatg ccggaattca gtccgctcat gcgatcgctg aggtattccg 133980 tgactacacc cctgccaaga caaaggcagg taagttagta ttggaatggg ctgatgaaga 134040 taagactatc attgttctta atggcggtta tcagtcaagc cttcaatccc tgtgtgaaaa 134100 gctgatccct gtttcagcta cgtacccgtg ggcctcgttc tgcgaggaaa aggatgctct 134160 taacggggca atgacggcag ttgctgttgt gctaccagag tatatgtaca atccacaata 134220 catggaagtt gcggatctcg tataccgacc aggtcaactg tcaggaccac aaattgcgaa 134280 tcagtatcgt gatgagatgg gaaatgttat ccacaactat acccaagtgg agaaagacct 134340 gattaccatg atcaaatctt tccgactgaa aggagaatag catgaatgat gttcgtggcg 134400 atactcttaa ggttggcgac tctgtttata tttatttcgg gtacaatgaa ctaaaacccg 134460 gcattataaa gcagatccgg ggtaagctag ccaaggtgtt ggttgatgca taccctaacc 134520 ggaaagaaga cgagagtcgt tactctttgt ctaagtggaa acctggtatc tgcatgatca 134580 aggcggaaga gcctactggt tattatccag atgaggtgat ccttctgctt gaagagatcc 134640 gccgtctgcg tgacgaagcc ccgatgaata aagatggtct gccaacaaag caactgtgtc 134700 agggactcct gaacttttgg gatatgaaac gcccgatgaa actggtaacc tcctaaggag 134760 agatgatgga aaatttcgaa gtgatgcgat gccactcagg aagtttggct tatggcacaa 134820 atctgccaac tagtgatgtg gatatccggg gtctgttctg cgcccctcct aaattcattc 134880 gcacaccgtt ctttaacatt aaagagcaaa cactggaaga cgaagaggat ggaaagattt 134940 atgagctgac aaacttcatg aagttgtttg ctgagatgaa tcctaacatt atcgagctga 135000 tgtttgtcga tgatgtggat atcttgcaaa cctccgaagt ttatgaatat ctacgcacaa 135060 tggctccggc gctgctgaca agtaaggtcg cattttcctt ctctggctat gcgatggcac 135120 agcttaagcg tattcgcggt catgataagt ggatcagcaa tcctcagcca gaggcaaagc 135180 ctacgcaaaa ggagttcttc cgcttagtcc acaactatag tgagaacgag ttccttgctg 135240 gggcaattaa acatgatcgc ttcatggaag caatgaacaa tctcaacgat atgtgtatcc 135300 ttgtacctta tgggaacgat atctatgggg tgatggaaaa cttcagtagc tcagggatgt 135360 tcaatgctga cggttcaatt cgccatgttg actatcagca actttctgat tctgacaagc 135420 ggagaaaacc tgtctttatt gtcaaatatt tggcagagga acacaaacag gccaaagaga 135480 agcatcgtaa ctattggaca tggaaacaga accgaaatga agttcgtcac cagctcgaag 135540 ttgattttgg ttatgacacg aaacatgcga tgcaccttgt gcggctgatg cgtatggcag 135600 aagagattct ttctgatggg aaggtcctcg tgaagcgtcc tgatgctcag gaactcctcg 135660 atatccgggc tggtaagtgg actcttgacg aactgctctc atgggctgac gagaaggacc 135720 attatatccg ggaagatttg tacaaaaaga cacagcttcc taaaatggcg gatcttgacc 135780 tgtttgccag ggttctcatg acggctcaag atatgtgttg gagtaaactg gtatgattga 135840 agcgctggta gggatatttg gtgttgcata ttcaatcatg gccgtggtat actcaatcag 135900 gatggaaaag gacacagtcc tgaagcaaat ctataaggcc aagacggatc gggattggtc 135960 tgaaatttgt tttgccatcg gttttgcatg gcccttcggg gccttaatcc actatgttat 136020 gaggagaaga aatgcgacag cttgagttta tgggtagaat ggtagaactg atttcagaat 136080 ggcaatcaga atataaaatg cacaggaatc tctccgaaga gcctgagaac tggcccgaca 136140 ccagagatca ggaagattgg atggaggatt tctttgtttg gctacaatgt aaggggtata 136200 cagtatgagt tatggtcttc tcactccaga acaggcaaag attatgagag aaagatacta 136260 tgcccagcaa ggcatcgaga aagttgtctg gccttctccc ggtgataccg ggactgtgaa 136320 gtgcttgcac gacgcttgtc cgaattgtgg tggcacgggt gtcagaaaag atggcactgg 136380 tttatgcgtt cacggcatct cttgtccttg tccgaagtgc agttttaagt gctgaatcgt 136440 ccctatctta tatgataacc ctgtttttca tgataaaatg gatctatcat taagatagga 136500 ggttagtatg tttcaaaaaa ttgtacgtga acaccctatc cttcgagagc actggcatac 136560 tctgctggaa aagggtttta tagaaaactc aaaaggttgc atcgctctcg taagggagcc 136620 tgtgacagaa gaacgagttc tcgtcataag ggatgccaaa aacggcatcc ttttttctat 136680 caaagttggt cgtctggacg tcactagggg ttcaaatacc ataagaccaa caacttacac 136740 ttttcgtgtt ggagacatgg ggaagctaga tccagaacat ctggaagagg cctttgatag 136800 ttatgaggga ttcgaagcct ctattcgcga tctctataga tcgctggata gaattatcaa 136860 tgaacacaag aaaacgctcg ggataaaata ccgagtaaaa gactggttca ggaatgccaa 136920 caaccgctgg ttccttctgg cggcagttct ctacggcctg ttaacggtat ttctgacctt 136980 gcattaagag gagattctta tgagagatcg tcaggagtat tatcgtcagt atgccgctcg 137040 tcgtcgtgag attgaccgtc agcggcgttc tacaccagaa ggtaaagcag aacaacttcg 137100 tatccgtctt gcccgtattg aagcagagaa acgcgccacc cttcatagtg agtgggatga 137160 gtttgtcagg gatgaggctg atcacttatg ctctgttcgt tgtgaagata ccggtattaa 137220 gtgggaacca gatcatatgt ttccgctaag ggcaacaaaa gtatccggcc ttaactgtgg 137280 tgataatatc caagtgatac ctgcaactct caacaggaag aagaaaaacc gtatgattta 137340 taccgaaagg aatgaatggt tgaaagatgt atagaagaaa cccggcgatt gccgggtttt 137400 tttttattga cctttggata gcttttctat cacgagatga tctgaatcgt ccaggtgcat 137460 caagtgatca gatcggatat catgcagata tgggagtcca tcaacgtgac aaagaaacca 137520 ggattcgtta cgagggtaat atccatttac acctaggatg gtcttctcca gcacaagaca 137580 gcgttttcca ttaaggatat tatcctcaga gaatccatac aacagacaga ttgaatcaac 137640 acaaacctta tggtctggct cattacgatc aggcatacca ctatcttcta atttcagcat 137700 tttttatctc caaagttaag ttcgccattc aacttttgta cacggtgagg gagaatttcc 137760 tgccaccacc aatccttctc gtgaagacga taagacacat aaacctcaac ggtatcctcg 137820 tccttacgga cggttctggt gtagatatcc cgaatggttg cttcgaattg accgtccaca 137880 aggacgacct cgtaaatttt gtacttatct tgttcaagaa cttcttctga cattttatct 137940 cctatttgat tctttttcca ccatgttttt cataaatggc gatgactttt tctaagtcta 138000 gcacagaagc tgtttcagtc cacccatctt tcatgtattc ctttgatata aagcctgtga 138060 ctactctttt tttacattcc ttctctgctt ttttgcactt ttctgctgag gagaactccc 138120 agacacctat gttcttagcc ttggccctgt tcatggagtt catctttgat atcctatatt 138180 ttgggtcttt actgataccg aatttaaaac cttgctcacc ctcgataaga tggatatatg 138240 aaaacttttg gtttttaccc gcacattcag gacacccaca ccccttatgg taaagtcggt 138300 cgaagttagt aataaaatca ccatgttttt ggcacctcat cgtgatctct agtgtctttg 138360 cattcttgcc ttcataccca cttacccaac caataaattc caaatttctc gccacgctct 138420 caatctggaa aattctttgt ctttcagtgt atctatagct actactacac ctgcacgcga 138480 gtttcccgct ttcaaaatcg gatctcctca tagtgaacca accatcacaa atacccgcct 138540 ttgaaaactc atccttgcga caaacagggc acttgtaatc gatatacaca tggtggcctt 138600 ttgcattggt tctttcagat tctctgactt tatacacccc ttttttcgcc gtctttgctg 138660 ggccagctct ggaaattttc ttagggggtt tttccatctt atgtgggacc ccctttaggc 138720 ctctctcctt tttcaggttt ttgaactcca ctactttacg attaagcagg cttctgactt 138780 cgttcttccg ataattataa actaacgcgg gaacttcgaa acctccgaac tcttcgtagc 138840 ctacaataca aaccatataa attagtaccc cagatcttct atattgtgtg gtaacatggt 138900 gttccaaaac aaccccctcc atattttttt taaatgatta taccaacaaa tttggtatca 138960 atcaactgtt gacaagacct ctctttctgt cataatgcca agataaacaa tttcaaagga 139020 gaaatcatgg ggaggtgtat gaaaaaattt tgcatctatg gccgggtaag cgttgacaac 139080 ggctggtatt tgtgcaaatc tggtgtcggt gaagacgagc ttgccaagtg gcttgcctat 139140 taccgtaaaa cttggcgcta tgttaagggg atttcttacg atgaataaat ttaggctaaa 139200 atgtcaaggt ggacgttggt gggtgcagga aaaattcttt gggttcctgt ggctgaccat 139260 ttggaattcc tctttgacga aagaaagtgc aatggcaaag attgcagagc acgtccagga 139320 aaaagaggat gaatgcattt actatccaac acgggaagag attatcgccg cagtctctgc 139380 taagatgatg cgaccaggcc caccaccagc ccctccttcc aagccttaat gaggataaaa 139440 actatgattt acgatgattt ggttttgata aagtctgctc tgaagaaatc tcggagcaat 139500 ggaatttact tcagggaccc gaagtggttg cagggcattt acatctacct ttctcaaaaa 139560 ggtagtctgt acatagtcta cagcttggga accatgtttg gaggagaggg ctatcgatgc 139620 actcagatta atgagcacgc cctccccagt ctcggccaca actttgagat ttgggaaggt 139680 tctatatgat tgaaatctgg aaaaccctgg gatgtgtttt catgtccttt gtgatgggaa 139740 ccgggctggc gcaaactgcc gagtcccatg attttgtcgg gatgttgctg tttggaatgg 139800 cctttgcctt ctggactaac ctctcccttc tacgtatttt tggcgatcat taggagttaa 139860 tatgggaagc acttttactg tccaatactg gacaaacgcc cacgaaggtg agtataaata 139920 ttatgtattc tggcagggcg aaagctttga cgaggcaatt cggcagatgg taaaatgtaa 139980 ggacaaaggc tacggttgcg taaagatgga gtggcggtga atgaagatag aaagcaagaa 140040 tatggctatg ggaacgcagt ctttacagca gatggcaaga gattaccaat ggtgggaccc 140100 gagtgggacc cccaatggga gatcgctctc aaacgaggag gttatctttc tgaaagccat 140160 caagaagtac accaaatggc ctttaacgaa agtagccgaa atgatgggaa tctcatacca 140220 caaggttata aaggccgtcc gattaagaga tcctgtgctg gttccttcaa gaatcccgga 140280 atacttttat gaggttacag ggatggtgaa gggtaaaaat ggtcccgaag gtactgctaa 140340 gaacatcaag gctggaaatc aagcactcag tgacgaggat gtcgcggtca taagggaact 140400 gcacaagaga ggatatgctg tggaagacat cgccacagcc tttaataaaa gtgtcggcta 140460 caccggaaca cttatcaggg gcgatagtcg ccacttcttg tccgcagacc ctgaacgggt 140520 gaaagaaaga atggtcacct ttgaaaaact gctgggtgat cgcgtatagg cgcgaagcgc 140580 cgcgccgtcc aaatccagta cccccaggta caccggggcc tggattttgc cgtcgatctt 140640 tttgtgaagg agttttcgtg ggaaatgtta agaaggcatt agagcatctt gatacaacgc 140700 gccccggtat ccggtgggtg gagggtgttt ctcatgggta tcggggcgca cttgcatatg 140760 tagaaaatat tcgtgcagcg gcagaggctt gttggtacat tcaggacatg gctgactgga 140820 caaagcgctt tgctttgaaa gaaaagacga aggccattgt tggtcatgat cgtattcttt 140880 ttggaaaaga gccttgacac ctcacggata gtaatatatc ctcagggtat ctaatcaaga 140940 ggaggagcta tgaatttctg gataatgcga gcgatcgtcc gcgatcactt caatgcggaa 141000 agaagcggtg tttatgagaa cctcggatgt ctgcctttta tcctgaaagt tgtagccatc 141060 gttctcatca tcgtggtact taatcacttt ggtctttggg agtagagtat gtttacttta 141120 gtatttacgt ttttcctgtt cattttgaac gcagtttgtt gtgggttgca gggattaaca 141180 cttctgcttc gtgaaaaaga agacccgttt gtttttcctg gtatcatgat gattgcccat 141240 gcattccttt cagcatggat gttcaatgtt tggtgggaga tggcaccatg aatatcttta 141300 cagatgcacg ggcctacaca ccgcttacac ctgaagagcg tgagtggata aagcaggaga 141360 ttgctgaggc ggaggcccag ctaaccgacg aagtgtggat cgaaaactac gtgaagggtt 141420 gccacgaaga tggcatgacc tctttcgatc gcgagctggt catcatgtgc attcaggccg 141480 acctttatgg tatgaagaga tgcctgaagc ataactatgt gattctttgg tgagggaaat 141540 tatggcattc actattattg cgttaattac aaatattgtt ggcggggtat tccacaccat 141600 acttgcttcc gacggggaaa ataagttttc ggcaattgtc tctgcgatca attggttctt 141660 ggttggtgct ctgctagtca ttcttctcca tgaggtggct gcatgacgtt caacgaagta 141720 cgctacatcc gtgtgtatgg ggaataccaa aacccggagg ttattcgagt atctaaggat 141780 ggtcgtaact ggtatcttgt aacaacagat gatgatgagg tcgttgagaa attcccgaaa 141840 gatttactcc tcacaatcag cttgtacgac aagtggatga atagtcttct atggagttcg 141900 ctcgtctacc atgcagagga taactcttcc cttgatgggt ctgacattgt gaaacacttc 141960 tggcgctgca cagattacat ggagcggatt attgcttcaa aactcaaaga agtctttcct 142020 tggtgtgagt gctcaaatga aagatattga taagatgggg acagagacat gcccacactg 142080 tggtggctac tctgccagta ccgttatcac agaacgttac atccttactg tagactttac 142140 tggcctacca tatggtcaag ctgataataa gattgtgtct ggagggaaga ggtttatttg 142200 tgatacctgt gggaaggatg tgtctaagtt tatacccaaa ctggagatat taaaatgaaa 142260 gttaatgtta cagaaaaaga aaaaacaagt gtggccctcc actctctctc ggtcggggat 142320 ggttttctgt ttgatggtta tccgcacatg gtgtgtgaat caaccatagg atattataaa 142380 gggttcatgc aggccgttaa tcttcgtaac gcgagcattg tagcgttgcc gctaatgcag 142440 caggtccagc caaccaacat ctctgtggag tacacagtgt gaataccctc aacacctaca 142500 caaaagtctt ccatttctgg tggcaaaatc tgggaagacc cgatatcggc tcaaaggatg 142560 aggcacttcg aggttggaaa gactgtatgc ttaagcagca cgaaatcaat gacaagggga 142620 gtatcctccg gggaacagat acttattgcc tagggtggaa cgccgctgtc gagtttattc 142680 ttggggagaa ttacgatgac aaactatcat gttttgaatg aatgggttct tgcaaacaga 142740 aaagggcctt tgttggttat ttacaaaaag ggttcaaaga gtattgaaga atgccttgag 142800 cttaccccgc tgaaaagtct acatttccac cacgacggag aggacctgag aaacagggtc 142860 tgcggctacc gggtgggtgg catcattgtt gaaccgggtg caaattttgg caaacacaac 142920 cttcgttatg ccatctcccg tcttcggtct gaggataatg tctacctttt cctgatggat 142980 gaggaacatg aggacatatt ggaagatatt tttgaagaat actacgagag tgccacaaac 143040 aaagagatgg ttgagagcct ccgtagccag atcgtaatct atgacccgga gtgcttctat 143100 ggcctacaga acatttgagg aatggaacgc ccgtgggagg atcgtcaaaa agggcgagaa 143160 agctatgggt cacctccttg acggaactgc gcttttcggg aaagagcaga ccaaaggcaa 143220 aaagagccgt gactggggag aggctgatct gggtgatgca ccagactcct ggtacatggg 143280 tgggcctgag gattattatt aatgaaacat atcccgttga agaagtgcaa acctataacc 143340 tactgcaaat tctgcaaagc catcggcatc cgcagacgct gcacatttat gacgaaatac 143400 caaccgccgt ggggactgcg tgactggtac aagcattacg cctgtgatga acacaaacac 143460 ctgattgaag accccgaccc acggggaatc atggaagctg ctgcaaagaa ccctgctcca 143520 ccacaaaagg ttgcacggga tgagcactac acagaagccg actaccagac ctggatgaga 143580 ctgtaggaga cagaatgtat aaaacaccaa aattgaaaaa acttaaaaac tttccttgga 143640 tcgaggatgt tgacggactc aaggcctact gtaagaaaat agcagagggg tctgagaacg 143700 cgcaaaaaga ggattgcgag gtctttattc taccaggtaa tttgcacgat atctgcatca 143760 aatacaccgc aggagatgta tttcatttag cagaaattat ggctacatgg ttcaaagagc 143820 ataagcatga agcagttatt attttgaagc aatacagaga cacaacatcc cccaactttt 143880 ggacaacagt cttaaatgta tacagatctc ctgctagtgt agctatggac ctttgggaag 143940 gctatgttcg tgatgaagag ggagaggccg tcaggatttt ggatatgtac gacaccagta 144000 aggaagaatg gattacaaaa gaggcgtata gcagaactgg ggtaatgaaa attcgaggtg 144060 gtttcaccac acaataagca cacaacaagg gagcctgaag aggccccttt tttattactt 144120 aaaacccttg acctgaagtg ccgcacacat tatactcctc atatcaacta cagaggagac 144180 acacaatatg tccacaacac aacaggccat tgagaaatgg aacggcacag tcccacatat 144240 caatatacct tcaccactgc tggatattca ggcataccat atgagtgcag gcgagtcaac 144300 attgtgtatc ataggtattt tattggccct catggtggca cttcgatctt tatatgatgc 144360 agtcacaggg gaatcgccat tgtgcaaggc ggggaatact tgggtctgca tggcgacaac 144420 ctataccgca ggtcatttga tttggctggc aatccaatac tggtgagtgg ttgaatatgg 144480 aactgatagt tcttttggtg ttgctgattg ttgccatagt ggtggtagtc cttgctatcc 144540 gcaccttatt cggagacgac gatgataatg acaataacac ccctccaacg ggacaggcca 144600 cccaggcaat gatgcggacc acaaaaaggg gttgacctga agaggcaacc ctgttatcat 144660 ttacacagca ataggtgctg aggctgcacg aaacaatcac catccttgcg taggaggttg 144720 taaatgagag tgcttctcat tgtactgcgt actcatttca ttaacacaca atctgaaggg 144780 actcccagac atgtcggtaa agataaagcc cctacagggg cctgcacata tcaaggatgc 144840 cctcataatc ctcgcattta aatgtttctg tgaaaccatc agggagccat tctttaaggc 144900 acaggcttct ctcgaatgat gactttatct tagattctac ctcaagagcc tcttctcttg 144960 aatcaaactt aaatacatta acaatgttgt gcttgaacat tcccaatttt tcctgctgtt 145020 tctttctgtt cgaggtgtta ttagaaatac caaccttaag gcatttgaaa aatggtgagt 145080 atagctcttg aatatacagt tctgttggtt tagtcacctc tcgtttaacc accttcctag 145140 gtttcttctt atgtttcatc tctacatgct tcttttcttg agcacaaact gaggggtacg 145200 aatgaagatc tttaaaatca acagttttta agcacaatac atccactgcc tgctctacac 145260 ttgttattgc cagatcctta ccgcagttag gacaagtgcc taacatacgg gtaattatag 145320 ggtctggggc acctgtaata ttaagtagca tagcgaggtg gatgtctgcc tgctcccaga 145380 attcctttct taccttagct atctcgttat cgaactcaat ctttaaggag ttcattttag 145440 atacaaggtg gtggttattt ttatagtttt cctgttgccg caattctctt tccgcacagc 145500 gcaggtgcat ctctacacaa acatactcca aagatccctg ttcattcacc accccatatc 145560 tccacccaca ccttgtgagg tatggaatag gctccccaac acaagaggtt atacctatat 145620 cctcagccag ttgaagcatc tcttttcttg tagccttgtc aaatatttgt ttaagacaag 145680 acctggattc attggtaaat acccagttgt caggttcgag ccatcttttt tccagtttta 145740 aaatcttatc gaccatcttc attttgtatc tcctccgtag gtatagtagt aactatagca 145800 ttttacacac aaattacaac ccccgccccg tggggaaatc aaaacatgcc tctgccgaaa 145860 atatcccttg ccgaaaaata tctgtctggg tgttttggag cattcgtact gtctgaggtg 145920 cta 145923 SEQUENCE LISTING <110> Optipharm.CO.,LTD <120> Novel Klebsiella genus bacteria specific bacteriophage KP12 and antibacterial composition comprising the same <130> optipharm1-64P <150> KR10-2017-0180949 <151> 2017-12-27 <160> 1 <170> PatentIn version 3.2 <210> 1 <211> 145923 <212> DNA <213> Artificial <220> <223> bacteriophage KP12 <400> 1 gacggacagc tccgggcgtc aaatatcttt acggatcttt acaaaatatc atgggcaagg 60 tcgatccggt ccccggtccc tcggggcctc ttcaggcgtg atagttactt gccgaaacta 120 ataataatca aatgtgacag atagcaagca tatggtttgc cagcttagag cacgatttgt 180 cattgacaag cttatattta tatgaattac accatttaac ataaaacacg ttatacgcac 240 tgaccaacaa cacatagcaa gctaataatg ccccaatgtt accagtgtga cgcacaggcc 300 agccacttca ggtcattaca tggtgtgact gttactgtgg tgatagttta atgtgtgatt 360 attcatgttt tagggttgtt ttgtgaatgg gacgacgaat gagaatcatt attatttcga 420 tttcgaattc aatttcgaaa tgagaatcat tccgcaaata taaatatttt gtaaatttat 480 aaataaaagc ttgacaagga gagagaattg tgtttaacac acagctctac tttgagcatt 540 tccgcaatga taatcattcc catcaacccc gttacggacc ggatacccgg caatgctaaa 600 gcattgaaat agttacaata agtaactatt ttctttattg ctacgcaagg gattgatagc 660 tatcccctat gataaattta tattgacact tcaggcaaac tatgctcaaa aacaacatgt 720 tttcattatc aataattctg gtttgtcaac cattattcac gatttaatgc gatttgatcg 780 catatagtaa ccatgtgtta tcatcacatc gccgcttcgc ggtgaagcgt ttagcttcat 840 agcttcgcta cgtaatcaca taccgacaca ataacacgag ggcgatcatg cgatagcgtg 900 atcggtgtta tcgtggcgat gtgataaaat taggctgtta atgattacgg atgtaatcat 960 ctaaatgtta atatttctaa ttcgctttta ggcgtctacg agccacgata acgcgaacga 1020 gaatgcgatt tgttcgcatt tgagttaccc tcgtgttatt gtgtcgctcg ctacgctcgc 1080 gccactcccc acgattacgc gaacgatttt tatttgacaa gattttattt ttatgctcaa 1140 taaaaccagt tcacacaata ggttagatga taaaagttat catttgagag tgattctcac 1200 actatgcata cataatgctt aaaaatgcat gttttattca gttaataaca tgcgttatta 1260 attgttgggg ttgttaggta gggccatacc attttaagcg caatatgcgc cattctgagg 1320 ggctttatct cttaccctgg ttagtgggtt accgcctgga gatctcgatt atgcaggttt 1380 tagtcaccta taactttttg attattgatt gataaaatct aacatataaa aacacaaaag 1440 ccgggagttg cccggcatta tttttgggga gtagtggagc cttacagcgc gatagccagc 1500 aggccagcga tcaagaaagg gagatcataa cggtctaaac gattaaagcg attaagttta 1560 atcagagtgt aaaacgtcaa ttgtaaaacg tcgatcatgg tgttaaaacc ttgcgccatt 1620 gtctcagtcg ttaccaggca agccagccag ttaaaacacg tattagacac taaagcaata 1680 aggcaagcca gcagggtagc gcgtaaaaga cttgttttgc ttacaatgta aatcatgttt 1740 gtcatttggt gttactcgtt taatgaggga ggtaaaagaa taacacacga aaaagggcgc 1800 tgcaatagcg ccccgatgtt taagctaatt caatctcaaa taaaacgccc atatagcgat 1860 catcacctga aagcgtagta acaattttca tacattcttc aaaggtccaa gccattgtag 1920 acccctggcg aacataagac acataaccgg tttttgaagt gcttttgata ttgtagcgga 1980 tatttgacat tttatttacc ttcggttttg cgggttggtt atcttcccgc cctgaaataa 2040 ataatagtcg aaaacatctg gctaggcaag cgttttgcct tttctttaca gcctcattca 2100 ctgattagtt taaattccgc ctcagggtga taaaggtcgg ccatatagcg ctttttgtaa 2160 tagaaagata cttccacaat gtggggcgct tcgatttcta tttgtgtgat agtcactaaa 2220 ccaggtttaa agcctggtgc aatgtccggt aattcgatga tcattccgcc ttttaaatct 2280 tttgctttta cagttctcat gatcattaac cttttttgcg tttcattact ttgattactt 2340 tcaggccttt ttgttctaaa aaatccgggc ggcgcaattg tgcggcgctg ctacggcttt 2400 taaccttgtt agacaacacg ccataatagc gcccgtcctc atgctgcccg atgaaataaa 2460 aatcatttac gccgtattcc tcatctcctg ccttctggat gatttcggct aatttgtcaa 2520 cactaatatt aatcataatt gctttacctc aaaggatagc ggggcgctag ccgccccggt 2580 ttgattattt ggttttgtat tcagcgatcc agcgggtgaa aatttgcgct tgcttttctg 2640 ctgcttcggc ggtgcggtgc tgcattactt caacatgcca acaatcagct agggtaaaac 2700 ctgatgcgtg agcggtccag ggatatgacg gatctttttc ttgatatgct ttcagcattg 2760 ccggatcctc gtggaaaacg tagggtttaa gctggctagc gttgtatgaa tcgccaccgt 2820 ttccaagttt ggcccactcg ttatggcttg atagatattt atccagcatt tcaaagaatt 2880 tagatttagt catttccgtt tacctcgttt tgtttagtga gtctgtatta tggggccttt 2940 cggccccgtt gtcaattagt ttaaatcaag atttagggcc agatcaacaa gggcggcgat 3000 ctgctgttcg ttagcgatgc ggcctacaac gtggcggata taaacacgga ttaataattc 3060 tttattgatt gcaaaacctg ggtgattcaa aagatctttt ttgcgaagtt tgtcctcagt 3120 ggcaagcgtc atcacgccgc ctttgtactc aatagagatc tgtaaaccat cggtaaaagt 3180 agccatgaaa taattttcaa aagcaacggt ttcaacgtgt aaacgtgcgc cttctttgtg 3240 ctgctgcata cacatagaac gatcataccc gaaagcgctg gcttgttcgt cgcggatgta 3300 gtaacggtca aagttagtta agcgcatgat gtttacctcg ttaagttgtt ttcgtttgtt 3360 tgccctacga gataaataat aatataagcg ggtatcgctg tcaatagacc tttacgtata 3420 tttacattat tcactttttg catctttatg catcgctatg caattgattt catggtgaaa 3480 ttacttttta gccgttttcc cgtgtcaagt tgtttttata tggcctttaa acgtcctgta 3540 tcgcgtttta agcggttttc cgtccaggct gtaccctagt ccattttatt ggagatctcg 3600 ccatattcac tattttgcat aagattttag gcgttgttga gagtaattct cattaatgga 3660 atagcgggca cctccggtgg ctttcctccg gtgtccatcg ttgccgcttc aaaaacagaa 3720 taacaaaaac caggaccgaa aacaagccct ggaattgtaa agattttgcc atcataccag 3780 gccggatctt ttcgcctttg caatgtcgga atataatttt ctaaagtatg ccgggcctcg 3840 atcgtttact tttacatatt catcacgcgc cgccacctgg agatcgtcgg gtaataatcc 3900 atgataacca ttgttaacaa tagcgatccg ttttttgttg caatcatagt aaacatatga 3960 tccatcggcc agataaattg tgcagttttg ccggatgtag ggtatcaaat aagcctcgcc 4020 ctggtgccgg attttgtaaa gcgccatttg tccattgtag atccggcgga cgtgataagg 4080 gtcattaatt gcccggtgaa tgttttcctt ccaggcctgg cgagcgttgc caacattacg 4140 gatcagtgct tccacctcgg ggatcacaac gttagcgcgg gcggcggctt ttgcctggtc 4200 tgataattca tcgtaataaa acattcgtac actaatcatt ttttaatccc catgaaagga 4260 aagcaagcca gatcggcggg gcgcaagtga tctacacgtc gccagccttt tgtcgtttca 4320 accaaaacac ggttttcaat ccagcgataa attttaccag atcgcatatt gagaaaacgt 4380 atcatttgca tttaccagta aaagttgccc cggcgatccg gggcctggtg tacactatgc 4440 cacaatggcg ggacggttta caacggtcgt ttttacgtcc tgataggtat catgtttttt 4500 aacggtagcc ctaaacttaa taaccgcgcc aaccgggcct aactcttttg atccgatgta 4560 ggtaaccaga tcgtcaccct ggcgaatttt tataatatag taagatgata aactccattc 4620 atcaattttc agataagaga aaataatctc accctcaaaa accaggcgat cgccaatgtt 4680 gccgatccaa ttgcttttta aatcctcggc tttacgctcg gcgcgttttt ggtcacgggc 4740 tgcaatgtaa ccatgatcaa gagcataacc caaacatgcc gcgcttaatg cttccattac 4800 cgggccgttg tctggcttgt ttgccatatc ggcaaaaaat aaaacatagg attctttaac 4860 atcggcaaac gttttaccgc aatgcttgcc aaacggaaag cgccccgctt cgatttcttc 4920 gatccgggcc gtatcgacga tcgacaattt accgcgacgt tgccccagct caaaatccgc 4980 atagcctgca aaaacttgct caaagttttc tgtattggcg atccgcgcgg ttactcgatc 5040 aaaatattcc tttgctttat tttctgcttt ttggggatcg gttgaaagat tgcaaatgta 5100 agaatctaca aaaacgccac cgccaaaatt acggcggcgc aatgtataca ttgcattcag 5160 ctttccggag tcgatgtaat aagtaacggt gattttagtg gtcattctgt ttacctcgtt 5220 ttgtgtggtt tttgtttcac ttgacaatgt gcgggtatct tatcccacac attaaccagt 5280 gccaacaaat tattcggcgg accatttacg ggcgtttttg cgattcaata aagcgacctg 5340 taagcaaaca cggcgggaat aattcaggcc ttccgctttc gcttgcaagg cgcgatcaaa 5400 ataatacttc gcttcttcgc ggcattcttg agcaaattgc tgggaaagtt tcatttcgtt 5460 tacctttatt ttgggccgtc gcaccattgc cgccctgtgc attaaatata ataaaagtcg 5520 cccacgtttg caagcgactt ttcagattaa ttttcccaat cagttagaac ggaaaacatc 5580 gttaacaata gcagttgtaa acatccagac tagatccggg gtagttatag gcaggctgtc 5640 agcctgtttt attgttactc cgcttctttc aagcgtgtag gcgataaaat gacggttttc 5700 aagtttcccg ctatgggatt gaatggattt ttcagtgcgg atcaggacag ttaaacggtc 5760 cgtttgttcg ctgtcattct catggcaaaa tactaacatg gttttttcac cctggcgatt 5820 aaagtcacaa ttgacattat cgttaacatt ttccagaaag aaaaatttgt ttgccttttc 5880 catactattt tacctttttc gcagcgggcc aatattgccc ggtccaagta atataaccta 5940 accgggccgg gggatcaata attatttttg ctttccggca tcggttcgac ttccggcgat 6000 ggtatgcagg ccggattaat ccagcgcccc tggcgctgat agtcaacggc gacgatctcg 6060 caagtcaatt gatcatcata gctttctact acataatcat cacactgttt taaggccagc 6120 gcactataaa aacacatacc cgcgaatact tcaaacatgt taaccgcctt attttttcag 6180 agtaatgatc gggcgcttgt caccctcttt gacgccagga tctaacgtat cgcagatccc 6240 aacttgctca ccctttttca aagtgtagct gttttcgtac acctcgcaag cttgttcgtc 6300 atcaaaaact ttctttacag tccaatcaca ttgtaatgac attgaactaa ccgagatatg 6360 gcaagctaat aaaataaatc cgaacatcac gccacctctt caacagtaga ttcccaggcc 6420 ccgtgataat caacgccgtt ttcggtgtcc tcatcacatg aatggatgtt atcaaaaagc 6480 aggccggatg tatagccttc attcaacatt tcgaaaattc tttcttgggc ttgctcttct 6540 aaaaaatcaa cgtggcggtc taatacttca ccgttattat ctgacttttt ccaccaataa 6600 gagattttga tttcgcgttt catttttcgg actccagaat aatatggata gcgacaaccg 6660 aacaagctgc cacgatgaaa gataccataa gcggcgcaga ttgcaagtta tttgttgatc 6720 tgatttgtct gattatagat cccatattga acacgggaca ctgtaacgga ttgagggagt 6780 aagcaacgaa cacgatccgc gcggttgtca tattttttga tatgcgccgg agtattgttg 6840 cgggtaaact taacacgcaa acgtaattta tttggatcgc ggtcatcgat tccggttacc 6900 acaccaaaag cgatttgacc atagttatga tacaccattt tacccaagaa ctttgattca 6960 agagcggcga tgttagattt tacgttttgc atgttgttta ccttttggtt gtttgtttca 7020 cttgtcaatg tgtaggaagt ataaccccac acattaacca gtgtcaactg ttataaacag 7080 aatttttcta gttctgactc acgaaaaagg aaattatcca ggccctttgc cacatttgag 7140 cattcaaaaa tccatttacc atttgaatct ttccaagcgc gattaatccc aacataacaa 7200 caaaattcag aactataggc cgttttatac atgttttgct tttccatagt gtttaccttt 7260 ttcagtgtgg cggtgaattc cgccactgat taaaggatag cataacgccg ccaggatgca 7320 acaaatattt ttaagaattg ttgagaactg ttctcatatg cagtgatgtg catagaaaat 7380 cgctgttatg caattagttt caaccggtaa ctaaattttc ggcgttttga gcggggcgcg 7440 gttatcggat accatctaaa acgccctcaa atcgattcta agcgcttcaa tgtgtaaccc 7500 tggtaagtgc attgctacgc tgagatctcg ccatattcac tattttgcat aaaaaagccg 7560 gggagttgtc cccggcctgg ttattcacct gctacggcgt atcgctgcaa attacgttta 7620 cgatccgcaa ggcgtttatt taacttcgga tcatactggt ccggcgacca ttgaaccgcg 7680 atccgttccg gcttatgccg tttattgtta cgctcgcgcc gctcgttagt ctcaccaaaa 7740 gcaaggcgat cgcgctggct tgtcatcttc tcaaagttgc ggctttttgc tgtcatatct 7800 tgatcccctg tggttgtatg tttccgctcg ccattctgcg atctgttttt tgcgatattc 7860 gatcagctct tcgatgtagt cgaaggatcc ctctttatgt accaggacca cgccgccccg 7920 gtgtttaatc tcacatatca ggccgctacc ctccagatca ttcaacggcc cggatcgcct 7980 ggtgtggtaa tcctccccct ggaagcgata ttctatatag tggaacattg ttttaaccct 8040 gtaccagtag taaaaccatt ttataacacg ccaggatctg gcgtgtattt ttgcataata 8100 acaaaatatg agtagaatca acaattcttt catattacgc ggcgctgttt ttaaatggct 8160 tatcccacga tccgaactgt agatcgatat agtgacccac attaaaatag tctgtcatga 8220 tgtcgcttct atcataattg tcagtgttta gcgcgttgat gattttttca agcgttgcgg 8280 taaactcttt atcactcgaa taagtatgag catgataatg gttaatgccg agatatgtaa 8340 agccgtccgg gtatccttct ttaactgatt tatgatccat tttagacaca agatcaaacg 8400 gcgcggatcg gatagtgcaa acaatagttg aatagtgacg gatcgcaaat gttgctttcc 8460 aaccttttgg caatacagct ttaaccgctt caacaatttt cgctttcttc tctttattca 8520 tgtaagccat gataaaccgc cttttgtttg cttgtctggt atatgcgcca ccttatcagg 8580 aggcggcgcg gatgtcaatc aaatgatttc ggtaacgtct gaatatttga tcgtgaatgt 8640 gctgttttgg tgacctggcg ccacaccagc aaggcgaccg taaaaagata cgcggttttt 8700 aacgccttca aaaatccacg tcctgccacc gatacgcaag cgggaaccga tagccagcgc 8760 tttgatctgt tttggtgtag ggttttgatt gtcctctaca acgtgccagc ctgccgccgt 8820 taaatcccca gggcggctac cgcgccactc ctgattgatc aaggtaaaat gccataagcg 8880 ccccaaataa taataaaact gttttcttac agctacatat tcaccgtgat agccttcttt 8940 cgcccatata tccatctttt tattgtattc aacctcgcca caaaagatcc caaaatagct 9000 aacctggttg aatgtgcgcg gggaaagcat gttagaagtc agttgtttag tattcagagc 9060 catgacagtt tacctcgttt ttgtagggcg ggacctattc ccgccttgag tagaattatc 9120 ggcctttcgg cctagcttgt caaatgatac gttcgaattt atcgaatctt tttgcggatc 9180 tgccgtgaac gtcgatcacg acgttggcgc gtttaccatc gcataagccg caatctaagc 9240 agctaatatt gtgagtggta ttaacgcaag tgatctcccc ttccaggcgt cgcatattgg 9300 gagttttcac gcggaaagtt ttataaccct tgcgccatgc tgtgatcgct tgcttttccg 9360 tatcagcgga gatctggcaa atagtagcga tccgatggtc aaaattttta tggtggagct 9420 ggtgagtata acccgtgttg ccttgcgtat ggttgaccat gttttgccat acctcaaaag 9480 ggaccgccgc aggatcaccg taggaaccta aacgaatatg acgacccgca aaatgtacca 9540 gatcgcgaga atcaagatct ttatagttgc cttttttgta agacttccag actgccagcg 9600 gggcctggtg tagcgttaca taacaagcgc cgtttaagct ggtacgatgg ggacacatac 9660 cgcaaacaga tgaatcaagt tttttagcgc tcgcttccag tgggctaaca tcttcccgca 9720 tgatccaggt ctggatcata tcgccggttt tatcgttagc ggttgacatt gtagcaatga 9780 ccacgatcgg ggccttatcc agaactgacg ggcctttata taatacataa cccttttttg 9840 ctgtggattt tttacccggt acactatgca cgatctcgga ttctgagttg acaaccagac 9900 cattattaag tttaaacgta gacattgctt tttacctcga tttatcgcgg cccttgccgc 9960 ctgagaaaac actttatcaa aggcgctaac tgaaagcaag cgcccaggat aaaatatttt 10020 atttagccag ggataaggtt ttgccgtggt tgatcccagg gataacccat tgcccggcgc 10080 catctttaac aggttgacgt aaacgcgccg ccgtggttac cttgctgtta acattacggg 10140 caaaagcgcg ggcctggtca cgggtagtaa aagaaatatt tttcatgttg taacctcgat 10200 ttgtgtggtt ttttgttttg attgtcaggt ccggggattg taaccccgga cactagccag 10260 tgtcaattaa atatttattc ttcttcttcg ggatctccat atgcactatg gatcggagtc 10320 tggcaattac cacatgggaa atcctcacct tcccagaaaa tacccacatc ggctggcatc 10380 catgccagat cactcccatc tcttaattct tccaataggc gggtaaaatt ttcatgcgta 10440 cactttgagc aaaggcaacc accatcacgc ataattaaaa ttttcggata cccaccgaac 10500 tcatacgggt ggcggatata attttttaca gtgtcgatca attgtttgtt agcggaaatt 10560 ttcattctat tttacctttt aagtgtgggc gacgtggcga cctgatgaga tgaatagtaa 10620 gcgctttacc aattgccgtc aatacctgga tgcaaatatt tttctaaatt tttcgcttgc 10680 gttttccctt cattagtata tagtagttat caagccgcca cggtggaggc ataacgagga 10740 tcgggcaatg accaaaacag aaaaactcac tcttgaaata gctattaaac acggtttcac 10800 ttttagcaat gattcacatt tcaccagtta tacagcagct cgccgggcaa taacgggctt 10860 gattaagaaa ggttttcttg tgcaggtgga tgacggaaac ggcgtagaat accagcctac 10920 acaagccgcc agggatttta tcaaatatgg tgtttaatgt gttgacacgc cccagggaat 10980 ggggcatact gtatccatac aggagaggaa acgcctacca acggcgctaa acttgggtga 11040 tggtagccgc agggcatcga cagctataat cgccggtagc tcgcctaaag tctatttgta 11100 aagaattgta aagacgcttg caacctgggg ccgtgtatcc tatattatac acatagcggg 11160 aacattgaaa ccggagtaca aaacaccggg ggtgcctgtt atttagcaaa tgagaatgat 11220 tatcattcaa ataactaaat aagaatgctt ctcattcaac aaaaaattta aatattgact 11280 tctgattttt catgtgagat actgagcgat acccctaaaa aattttttcg cgtaagaaaa 11340 caaatacgat cttgaaattg agatctcgat cgagaaccgg gccgaaaaat tttttctaga 11400 gaaaaaacaa ttacgatctc gattttgaaa aaccgatcga gaacccggtt gatatagaga 11460 aaaatttttt gatagtgaga gcaaatacgt ttttgaaaac gaaaagtcga tcgagaaccc 11520 agagttttct acctgaaaat ttgagatatc tttttcgcct atttgagata aatgtccaat 11580 cttgatgcca agatacctat agcaatcata cgcttgtgca tcatttttcg acatagctcc 11640 cgcaaaggtt tgagataatc tactcccaaa actcttgatt taaaaatttg cagggaagat 11700 gaaatccatt tcaaaaacga ttttgaaaac catttcgaat tttaaaatat ctttgggata 11760 ttaaatatca tacaaatatc acacagtttt gaatcttatc tcggactgaa aatcactttc 11820 cattttaaaa tatcataggt tgtacctgta gaaatctcat acatttgaat ctcatctgga 11880 gtcggattac aaatgtcaat gaaaaatgtg ctcaatacag aaatcaggaa ccgttctgtc 11940 tttcctggga ctgtgtaaac aatacgcata tcaccgggaa taggagaaag gaccaaggaa 12000 gtagggccat tcataagtgt aacggtatta tcagaaatct tgatacgacc atcgacacca 12060 tacaccaaat catgagcaga agaataatgt gcaagcacct ctactaccgg gttaccgaca 12120 aggttcacga ggtaatcaag atacaggtct cgccatcctc gattctgcat catgtaccgt 12180 atatgggagc ctccatcaaa catctcaccc agttgctctg cgatccaggc aacaccattt 12240 gcaatgtctt ctctgttcca ggtattgtcg atatctaaga tatccttgct gaacttgttc 12300 atgcgccgca tggcattgag tacatactca cctctttcaa caaaggcacg ttcagtgtcc 12360 ttggcataat cgagaagccc ttcaacctct gaacctgtag cgtattgctt aaggtcatca 12420 agcacacttt ccacgctggc cttggcctga ttgaaagtca tctcatcagt ctcgtcatta 12480 gagaattcta caccaccaag ggcatatact gcatcaaggt aaagcctttc aaggtcgctg 12540 cgcacgttag gaaaatcata actaaccttg ttatggggga taagttcgag agtgtttaaa 12600 atagtggtca ttgtatatcg tcctgtaatc aatcctgagg cgttttatgc aaaggcagta 12660 cgtttgccta ccttatgtgc taaaaacccc gctacggcgt ttctacgcat catacggggc 12720 atcatagcat ctgtttttca gtcacgtttc atttggtagc gcatatacgc catattcatc 12780 ttgtgtttga catcgaaagt taccgggagg tttccaaaca ccaggtagca gacatcatac 12840 atgatctccc agaacttaaa aaccaaatat ttagaccgtt tttctaagct catcatctca 12900 cctccacagg ttcaataaaa tagttctgac cttgttttgt ttgacaaaat gaaccaacgt 12960 accagacacc ggaaccacca tgtgggtgct acggaggata tcatatccgc gaagcttttc 13020 cgctttttgg acattttctg gtgcatcgac tatcttcatc agcaaatcaa aaccagacat 13080 cgacatcagg aacttgttcc caccttgatc gaccatttcg atattagcag cagaacgacc 13140 acgactgaat ccagtgtact ggagtttcag ctcgcgaatt tcatgacgat cggaaacatc 13200 caccttatct tccatcttcc agtcatgggc atacccggta taccaagcat tactgccttt 13260 gaggtatagt gcgggatatc cacgctttcc taacttagcc atatctcacc tcctgtggcg 13320 ctgccggcag cggcatccag tgagttggtg tccatgacgc gccggggatc aaccagccgc 13380 tactctgcga atctgggtgg ccagggatat acgttgccca tttgcaacac caccgcggct 13440 tctctcccca ccaacgcccg accaaaacct catgacgact tggcggcatc tgctcgctta 13500 cctgaatcca tccctggctt tgcgctggag tgtcgccgtt ttgcgccggg cagcaatcgg 13560 attgcgccgg agagttgcca ggatgcagca tggcggcgcg gcaggattca tacttcgcca 13620 tcacgaccaa aacgccatga ttccatgcat gctcatcaat tgagtcgcac gttttacatt 13680 cttcaattgc cgcttcgaat atcgacacat catccggcac taccggagag ttgccagcct 13740 cataagctac gcgcatccag tgataaaaag cttctgcggt aacacagccg caatctactt 13800 caataacccc atcttgttgc gataaccatt cttcgaattt catggcttac cctcgttctt 13860 ttcaatacca aggatcatgc cctggagttg ctgtttcatt ggaatcagga ttggcatatc 13920 atcaatccag acatctggtg tccagccgtt ttctgcacac acttgggcct tttgtacacc 13980 actacagtaa attaccttga tatccatctc tttagcccag aattcaatat ccgcattatc 14040 atcagttgga tatcgaaagg taacgaaacg aacatcaaaa tcaccttcga tgatcatcag 14100 gtcaacaatg tgttgccaca tggttggatt taacgtgaaa gtatcatcaa agtcaagtgc 14 160 tatccgccta cgatcaaata gtttcatttg cacctttttt actctcttgt tcttcaaaga 14220 agagttgatc tgccagatta ttcaggtggt ttgccacctg acgggcctga gtacgagtga 14280 gacggatgcc tgcattgtca cgatcatcgt tggtcttatc cgtcatccag agttggatca 14340 gaaccattcc tggattacag caagattcca taacttctgc tcgaccacgg taaaattcag 14400 tatcctcttc aacctctaag tatttttcca ttattgctta tcctccgcct tagatttctc 14460 tgccttttct tttttcgtag tggcatcaag ctcatcagta tatttcttga tttgagcatc 14520 aagatactta atggtgctat cagccagttg ttgtgtacgt ggtgactcaa ccacattctg 14580 acctacatac gccgcaagca ttttatatgc tgtttctttc tgtggcataa agttagcgta 14640 caggatacct aggaaacata caaccatgcc aaagactgcg atcttacgtg gacctttggt 14700 aacatccttt accacaacag gtgttgttga ttggctctcc ttccgggtta ctttataaat 14760 tgtggactgc ttaatatagt tgctggagag ctttccatca ggcaagcgaa ctcgaagtgt 14820 attatcactg ttccataccg taacgatctc aatcgtatcc ccggccttat atccactcca 14880 gtcttggtta agaaccagat tttcaccttc gaagaactga taccctaagg ctgtaccatt 14940 cttctcaaga tcttcataaa tcttctgacc gaaatagcag gcggcgtatg cgagagcaga 15000 gataaacatc agagcaaccc aaccaccata attaccgtct gtagtaagaa catcaatcac 15060 ataaatcaga aaaggccatg aacccatttt gtaatctcct cttaagataa ctttagttaa 15120 gtgttaaatt tccaacagtt tcgatgaagc cgaagggcat ggaaaatacc ttcaccatat 15180 aaatcttgtc cttaccatct tcatagtaag gcacaactac aacatcatca gctcccagag 15240 gaagcatagt cataatcata ccagaatcta caacgtattc aagcacagct tctttggtgg 15300 caggaatttc tttctctgtt tgtttgcttt ccaacaggcc accacggtgt tgacgaatac 15360 ggattgtttt catttatttt ctctccagcg ttgcgggttt ttcttcattg aatgcttggc 15420 ggatgcccat atcgtatcca acacggagaa tctctctttc gatcaggaac tctatatcgt 15480 gttttaactt atcatatacc gcatcaggaa gtctttcaac aacccagctt gcaccttgag 15540 agagagtaag ttttgccatt ttcttgtcgg ctcgcgccgc ccccagttaa tcgtcgcatt 15600 tagaagctcc tgtcgcccgt ggctccgaac acattgcact tccacacaca tctaacaccc 15660 gtaaacgggt tagctcatag ctaatccact tgtggatgac tgaagtgact catcacttcc 15720 tcttgaaact aactatacac taactaaacc atagatcaag atctttttat aaagatctat 15780 gttttaggtt ttaagatctt atgtgtatta ttttatatat gtattcatgt gcaaaatttg 15840 catgacacga gacgcaaaat ttgcatcaca acacggtata ctcatacgta ctcatccctc 15900 tgcgttctgt cgatagatac cctagtgcca cgaggttttt tatggatgtg ctgattgacc 15960 tttcagacac acccgtagct tcactaatcg ttttataact agcaaagtat ttcttccctt 16020 ttgtctctaa gtatcctgcc ttgtacttta tgtggagcag gacacgaaga tctgtgcatg 16080 acaggttctt atcatgcagc tctttttcgt cacaagctac ccacttctca ctcttttttg 16140 gcatccaagt atttctccaa atgagtgagt acaacctctt gggcatactc ttgagatgca 16200 tcattgtggt gaagaacagc cagatcacat ccaagtttgt gcaaacttct ctcgaatgga 16260 gacaagtgtg tcatcataac ttcgaccaga ctaagctctt cttctgtgat gtggagggga 16320 tcatccgtga aatccctgga gatgagaatc tccctctcac caccttctcc ggcaccatat 16380 acctcgacaa tcttcctgtt acagaaaatg tcatacctat agccagtcag atcatgacca 16440 tcttgtactt caaagttcac aatgagacaa caaccaagcc ccatcaagta aacctcaaaa 16500 tctaaattgt ggacaatttg catactcacc tcgtaattcc gtgattttca tggaaattat 16560 actctttgtt agcaattttt ctagccgtta tggcatcctc taggagatca aacctcccta 16620 agaatttcgt ttttccatct acccttatat acgataccca tttatttctg ctctcttccc 16680 aacgaacccc cgtcaccccc gatttatttt taatattaat tttaaggttc ctcccattac 16740 cttttacagt cgtaagtcgg agattatcca atctattatt agacctatca tgatcgatgt 16800 ggtcgatgac cataccttct gggatggatc catgtaccat tatccatatt gccctatggc 16860 aatcaatacg tacatagtct atacaaagtc ttctatagcc attcttatcg attcttcccg 16920 ccacatctcc agccttaatg actgtattct tttttgattt tttccagtac aaattgcccg 16980 tttccgggca gtaggtaagt aattcatcca ggattttctt atttaaagtg ttcatctaga 17040 tccacagctt tcccaaatgg cggaatccaa cccttgcgcc caccacagat aacccagaga 17100 gtgttgtact tacgccccca gcttgcgcca cgatgtctca ggtcctctat gtaaccatct 17160 gtgaagatta taacctcttt tgccttagga ataaactcat cgatgtactc aaatgcacat 17220 gcggcagttg ttccaccagt tgatgtaact ctataatcca gaatttcctt tatgttgtcc 17280 tgtgtgtaca cgttgacgtt gccaacttgg gttgaccaac agaacaatgt gatacggaaa 17340 cattggtaca gggtgctcaa agcgattatc tcattgaaga tacgcgtcat tgtttgacga 17400 gagatagaac ctgaaacgtc aaaaccgatt acaatatcaa cagtctctgt tctttttctg 17460 ccaggcataa ccatgaactg tctcttagtt agagcgccgt gatcacgaag gacttttgtc 17520 attccccctg atcgacgacc taagacccgg taagtacgat cagatttaac acgagaaatc 17580 attcgttgtt taattatttg caggtaatta atcttcggtt tacctttttg tgcgattaat 17640 tctctggctt ctttcggtcc ttcaccgcct gcggctttca tagcagcgtc aatcatgtcc 17700 tcagaccaag acatatcctc atcttcctga tcagcagact tctgtgggtg tgggtccgta 17760 taccccagga tgtccaggtc tttatcataa tccccgatgt gcgcccccag cggcttacct 17820 ttaccatcac cagcctcatc cggcaacaga gcataaatct cttcagccgt tttcccctcg 17880 tactgatagt cacaatagca gtaagcaagg aatccaaatt cttttgtctt atcaaagact 17940 tgccgatgag tgaaccattt caaactctcg gctttctggc ccaactcctt gaccaggtcg 18000 gtgttgatat agtgatcggc tgcgatattg aaacgtctac ggtcaaatgt tttcccacga 18060 gacatatggt cgttggtgac atggcggacc tcatgcatta gaataaatac aatttccttc 18120 atggtttttt gacgatagaa gacatcaaca tattctttat attcatcttt ttgctgttgt 18180 gtcatcatcg gatgcttgtc aatacgagca aaaacctttt tcttgcgatc aacaggcata 18240 cccataatga actctgggtt aaagtatagg ttgcgatgat cagtcgctgc ggttggaagc 18300 catgcacagt caactatcag cggcataccg cttaatagcg tcccgtagaa tggtcgatta 18360 gtaagtaaag cgatgcgggc agactgaact ttcttcagtg cttcatcagc cagttccata 18420 atgctttctt tttcatctat atacattctt atctccaaga aaaaaggcca tcagttacga 18480 tggccttatt atatgttaat tcatcaccct ttgcaatgca atttggggta aaaattcatc 18540 tatcccttca atcctgaaac cccaggccaa ttgcggaccc ggcgctccag gaaggtgagg 18600 aacagcaaac aagacgatcc catcaatagc tccgcgaatc gcgttctctg tgaaagtctc 18660 taccagatcc ccgaaactaa gacccggcct gaagccagca ttcagcattt tttgctctgg 18720 tgcggatgca ggcctgccca agatatcctc gtacattaca ccaccttgtt cagcattgct 18780 gtaactttag gcaggctaag acccgtctgg atcatcagtt gagtcatagc agtttccatt 18840 ttcttggaga cgatgatgaa attatctttg gcaaagccaa tgttaagatc cagaatcaga 18900 atggatttag gctcaccagt aagcttctct ccggtcattg cacaggtgct gcgaatatat 18960 ttggccttga actgagcata tgtcacactt actttcatac cgacatttgc aaaagtattg 19020 cagtaatttg cataagcaag cgcaacagct acatcttctg gcagtgcaac actgatagct 19080 tctttcggtt cagcctccac ttccacaggc gcagtggttt cttctgccgc aggcagttgt 19140 ttgtgttcgt gttcagcaag ctctttgtag tcggtgttgt gattcttttc tacttctgcc 19200 atgtgttctt tcatgtccat ttttgtctcc tgttgtggga tatatttagt tttcagtttt 19260 tcgagatggt ctttagacat attcagcatc atagcctgca caatctcacg gtctagcgga 19320 tcaattatag tgatggctgt tttcttgtca accaaacgat ctttcaattc attggctctt 19380 tgcaagacaa cgcatacatt tccacgaaca taacctttct tatcgtcaat gcgctcaact 19440 gtcggataca atgggtcttt ttcgccatgt accgacctcg tgctaaagtt catattggtg 19500 tagtcgcacg ggccgatgcc caaaagcttt tctcccatca tgaaccagtc atcaagggtc 19560 aaggagaatt ctaaaccccg tttctttgtg cgttctacct ttttatgata ccgttcttct 19620 agacttttaa tctcgctgtt ggtaaatttc tttttaacat caaacatttc taactccttg 19680 ggtcttaccc gttcttagta aggtgattat caccattcgg aaaagagttg tcaacccttg 19740 atttctaaaa agtggcggtg tatctttgtt cattatttgt ataagagggt aagtgagatt 19800 atgagcaaag tagatattaa tgtaaaacca aacgagactt ggaatgagga gcgggatttc 19860 atagataagt tgttacaagg gaagcaggct gctcaagaga gatttctttc aacttttgag 19920 agggacagac atgttgacaa tcctatcacc cgctttagag attatcttca aggggtacag 19980 gattcgaacc ccatattgga catatttttg tcatgtctcc ataaactccc ggcgcatggt 20040 ggcccttttt attggcaatg gcattccggt gatgtccggg agtatggttc tgatatgagt 20100 cagaagctaa atgtttcacg tatggaaata ggccaccaat cacatattac gggtggtgac 20160 ccttggacac atcgctttgt agaaacaatc tccatcgata tttatggtca cggttgcggt 20220 gaagcatttc ttggtgggtt ctgcaatttt aactaccgta ctaagtattt tcttgagtgt 20280 gtaaagcagc ttttggtggg gatgtcacac aaagatgacc ttgatctccg tttggttgtc 20340 gaatatacca gctatcaaaa aaatgcccct gtccaatctt ggatggccca taatggggag 20400 agattaaccc ttaaaaatgt aagcctcatc agtggtgatt tggttcttta ctctgactat 20460 cttgagcctt ccgcattaga tcgtatttgt agccaaataa atcattctgt tatcaacatc 20520 atgaacagaa agatcgctaa taaggcacgt aaggcaatgt ttgtttgttc tccgaaagaa 20580 acgatgttcc acttggaata tgaccccaag ttacagagta tgatggaggg ggactccccg 20640 acagaagaag aactcatgat gatgtctatt gcagggtatg aagatgagtt ttggcttgac 20700 aacgtaaaat ctttcgatag actgaacata aaacccttta acctagagga agctgtcaaa 20760 tggtatcaac agacaagagt tgtattcaag ctttaagtcc ggcacaagaa cttgctttag 20820 caattaaaat tgcagcagaa ggccacctga atcagaaaga taagggtggt aacccataca 20880 tccttcaccc tctgaaggta atgcactatc tgaagactga tgattttcag cttatggcta 20940 ttgccgccct acacgatgtg gtggaagata ctgatgtgac cgctgcggat ctggttctgc 21000 taggcttctc gaaccgtgtg aaggatgctg tggttcttct gacgaaaacc cctaatcaga 21060 caccggaaga gtattttaac cgcctggccc aaaactatga tgcggtacgt gtgaagcttg 21120 cagacctgcg ccataactct gatgttcgtc gtctgaaagg tctgacagat aaggatttgt 21180 tacgtgtccg taagtatcat gacatgtatc ttcgtctgac aaagatgaaa gaacaccacg 21240 aagcgatcaa catgttggct acattatgat cattacgaaa aaatcaaatg gccttccttg 21300 gttcgaaatg gaaattcctg acaaggttgt agtatgtgcg agatgttttt cgacttataa 21360 cctgaaagat gctcctgtaa aggcccccga tcagcttcgg attaaggaac cttgttgtcc 21420 gaactgtggt tttaaatggt atttgtcatg aatctctttg tatgaagaca aatcaaaccc 21480 agcccttgaa ataaaacttg gagaacttta atggctaact ggaaaacagc tctggaccta 21540 cgtgacatct ggaataaacg gaatggtgaa tgtggtcggg aagactggac agataagacg 21600 gtgcatgagc ttgctaaaga gatatcccgt cgtcttgaac ggaaatttcc tcatgaatca 21660 aactatgata gcgacctctg cgataccgag ttgtgtgata taattggcta tttccgggat 21720 gttccaacat accaggattg gctagactct attgcagaat gtgagagtga ggggtatgat 21780 gccgacccaa tccgctatta tacacctttg cgggaattca acgacatcat gaatgatttt 21840 tatgattggt gtgatgaaaa tcgtgtatgg gtggataaat aatcattgca atgggggagg 21900 atcaaatgta tcctgctccc gaatttcatt tacaggagac aaataatgtc aagtcgcaac 21960 atcttttctg gtaactggat cactttgaga gatcttccac cactggtgca attttgccag 22020 cgtcacaaac gttcactgat gatcttcggt ggggcaggta ttggtaaaag tcaagctgtg 22080 aagcaaattg cggattctct tttcgggccg ggtgataact tggtagactt ccgcttggct 22140 gataaagata acactgacct caccggggtg cagattccat acaccgatga caatggtgtt 22200 actcgcacag tgtacgcctt gccggatttc tggcctcgtg atcctaactg gaaaggtatt 22260 gtgtttcttg atgagcttct ccacgcagag ccttaccttc agaaactggc attccaaatc 22320 atgctggacc gtcgaatcgg gacctaccag ttccctgaag gggctgtact ggttgctgcg 22380 ggtaaccgtg ctggggatgg tactgccgtg actgcactgg aagctccttt ggctaaccgt 22440 atgatgctgg tagagcttac ctatagcgca tcggtcttca tcgaagacta tgccatgcag 22500 aacggtattc attcgtcaat cattggtttt ctgtctcgta agaacagtgc tattgaaaac 22560 tatgaagaga tgctggatat cgggtgtcct tctttcgcca caccgcgtac tttaacttac 22620 gccagtgatg tattgtacga ttacgatgct aatttgctgc ctgccaactt ggctaaggtt 22680 gctctccagg gcttcatcgg tacaccttta atggctgaac tgtgggcata ccacaccaag 22740 atccgtaata tggttccgat cgaagacgtt atgaacggta ctgcccaagg tcctggagac 22800 cttccatcag acagcctgtg gattttgggt tcagaaggtg ctatttggtt gcgtaaggct 22860 attgcagata ccaattacac ggatgaccag attattgaat tctctggaaa cttccttcag 22920 tatctttacg atcactttat ggaccagaac cgagacttcg taagctctat cttcctgtcg 22980 ttcattaagg aaaatgcgtt tggtaaagct ttgttgacca ctgcgagcaa ccgtgacaag 23040 cttcctgcac gtttgttgaa ggcaaagcct atcataatga aaattatggc agacttccag 23100 gtcaactacg ctgaagatat taagcttatt gaaggaaaat aatattgaca gcccctccgg 23 160 gggctgttat gctttatgca tcaaacaaaa cgaggatata ctcatgccga aattaaactg 23220 gaaagaagca cagcaggcta tgcgtgaagg taaacgtatc cgtaaccaat atttcacttc 23280 tgatgaatgg ttcgaaatgg ttgatgggcg tatctacgca gaagacggtt gccctatggc 23340 aggctggtat cgtggtgaat catggcagga tgaaggctgg agtgtgatcg aatgatctac 23400 aaaaaccaac tccgcaatat ctggcgcaag tttgttaacg gtaaaggcta tgtgtctggt 23460 gaccaaggcc tcacctggac agaaaatggt gctcctgagg acttgatcaa gcgattacct 23520 tattacgtgg agagaaagga tggcaaaatt caaattccca gtttctgaac taaacgagtg 23580 ttggtggctt gacaccgccg actgtgttat ggcaggatac acctatcgac gtcatcgggt 23640 gtttgttgtc tgcgcgaaaa atcgttcgga tgctattgaa tccatgaaag agtttaaaga 23700 gaggagttgt aaatgaaagt taaaatgacc gcaagttaca gcgaacaagg acacgccccc 23760 caaaaaggtg atattctgga tgttctggag gaagtgtata atgggacatt tattgactat 23820 taccgttgtg agtggaaagg ccaagacctc gatatctatc catacgaatg tgaggaagtg 23880 cgatgacgat tcttgatgat tcaaaaccga aacaggtatc aatcctgaca attgttgggc 23940 gggttgcaac attctcatgt gacgactttg atatagagat cattggagaa catcacgtca 24000 tcacaatgaa ggttcctgac cctggtggtt ataaaaaggt taaggctcaa taccttatcg 24060 agcctatcat gagcatactg aacgaggatt actaatgaag gagagtgaag aggcattaca 24120 ggcgcttaaa tcttccttct catatgaccc tgagacaggt ttttttacgt gtatcaatcc 24180 tctcgctcgt cgttattttg ggaagattgc aggcacaaaa agaaaagacg gctacattgg 24240 acttgctgta acgattgatg gaaaattgaa aatcttctta gcacacaggg tcgcttgggt 24300 ctttcatttt ggcgtttggc cttctcattt tattgaccac aaagataaaa ttaaagacaa 24360 caatcgtatt gacaatttaa gggatgtcaa aaagtcggta aacgtctata actatagcag 24420 gggcaagaag aaccagacag gtttccgtgg tgtgtttata gatcgcaggc gagagcctgt 24480 aaagtataat gctgcttatg gcaagaagca tcttgggact ttcaataccc cagaagaggc 24540 aagcgcttgt taccaaaact atgttaaaac tattcatgaa attgtggtgg aggactgatg 24600 ttcaaatata aggttgggga tttaatagag gcggtaaaga gtggcgaaat aaatgttttt 24660 ggacacggtg caaattgttt ttgcacaatg gggagcggaa tcgccccgtt gatcaaagaa 24720 gcattcccta agatgtacgc tgccgatctg aaaactgaga agggcgataa gaccaagctg 24780 ggaacctgta caatggcctt tttgaatgat ggatctctcg caggatttaa tctgtattcg 24840 caatacggct ataatcgtcg taaacagggt ctcagggacc tcgattacaa tgccctgtac 24900 gattcgatgg ttgagatgaa aaagctctta cagagctata cagacggttc tatggctgac 24960 tacaaaattg gcttccctaa aattggtgcg ggccttgcag gtggggactg gaatgtcatc 25020 gaagcaatga tcaaatcaat cttctttgat tgcgatgtga cagtttatgt cttgaaagaa 25080 tgggaaatcc ctggttacta cccttcagac gacggccctc tgacatcaga acagatctct 25140 gccattcggg aaatgacaaa atgtggatta tccacagggg ggactggatt atcgtggtta 25200 aattgagaga cggtatggta gcacatacca aaaagatcga cctttatgtg ggtaatacgg 25260 tgttaaccta taacgcccct cgtggtcaga gctttgccat actactactt ggggtagaga 25320 aaccaagtgg tgacggcacg ggtattcaga ttgacgaatg gctgaatagt cgtggctgga 25380 agctggaggg tcctgatgag taaatcggtt tttgtcatct atgacactgt tgacagatgc 25440 ctctggaacc acaaagccaa gattggatgg attagctctg gcgctgccaa gaatgcgtgg 25500 aatcttgtcc acgcaacctg gagtgggaag aagtattttg atgaccaaca aagatatgta 25560 gttcttgaac tttctggcgg acacattagc aaattatttg aggagaataa aattgacaaa 25620 accaattaaa tacccaagca ccgcacagtt ccgtcaggtt atccgcacca tgcatgataa 25680 actgacgttc gacggtattg atgaagaggg taatattaag cggaaggtgt tgccaccgga 25740 agcgtacctg atcccgtaca tcggtacggt taagcttcac ggcactaatg gcagtgtggt 25800 attccactct gaggatgaag ttgtcttcca gtccaaagag cgtgtcgtga ctgtaggcga 25860 cgataacaat ggcttcgcgg ccttcatgtc tcgaaaagac accgcagagt tgctttctca 25920 ggttaaatat ctgtgtgaag tcaatgacgt tgagttccag ttcccggttg aaattgctgg 25980 tgaatgggct ggtcgtggca ttcagaaagg tgttgccatc actgaagtag agccattctt 26040 tgctatcttc cgtgtggctg tgggccggga tgaggcaacg gataccctca actggctacc 26100 accaacgttc cagtttggaa ttggattgcc ggatgctcgt atctacagta tccttgactt 26160 tggttactgg atggctaata tcccattcaa tgagccggaa cttgtccaga atgacctggc 26220 agaactgact cgtgaagtgg aaaacaaatg cccggcaggt aagttctttg gcgtagaagg 26280 tatcggtgaa ggcattgtct ggtctccaaa agatcctgag ctttctaaaa tctctggcct 26340 gtggtttaaa gttaagggtg ataaacattc tgtatccaaa gttaagaccc tggcggcaat 26400 cgacccagaa cgcctcgcaa gtatgcgtga gttcgttgag tacgctgtga cggaagcacg 26460 tcttgagcag ggtgtcagcg aagtcggtct tgaccagact aagatcggtg aattcattgg 26520 gtggattaac cgagacatca acaaggaaga gggtgatgtt ctggaagcca gctccatgac 26580 catgaaagat gttggcaagt ttatcagcaa caaagctcgt gcatggtaca tgactcgtct 26640 gagtgaggag ggctaatggc cctcattgta gccacaacgc ggtctgttga aaaaagacct 26700 ggacattctt tcaccgagtg tgataccttg attttcgaag acgaagaaca gggcaaaaag 26760 tttgttaaag agaacaaaca gtttgtctat catgtccaaa aagcgagggt cattaagaat 26820 ggtgagacca gaaccgaagt ttaaagtcgg gcagatagcc aaagatactt ggagcggcaa 26880 gataggtcct atttcaacca tgtacttttc agaaggggat gagtacaaca aggccgaatg 26940 ggcatattct atagaccata tcgggtggtt attccatcca gagtcggact tggaggcggt 27000 ttaatgggtc tgcgtgaata cttagcagtg aaattaaaac atgcaaagga gcaatctatg 27060 gttaaagtga atggtaatac catcactatc aatgggaata ccgtggttaa tggtagcatt 27120 attggtgggg acttgagtat ttctgcaaat ggggataaaa tcctcatcaa cggaaaagag 27180 gtctacgcca cttctgataa aaacatcatt gtggtcatcc acgggaatac cgggagcata 27240 aacaccacat ctggggatgt gaaggtgtat ggcacagcag gtaatgttaa gactgtttct 27300 ggtgatgtcc gtatcgaaac agggtcactt gcagatgtga ccaccgtctc gggagacgtt 27360 atagcagaaa ccattgaagg taatgttaga acagtctcag gagatgtctc tcaccgtcgt 27420 tgatatacag ccccgcaatg gggcttttta atttggagtg taaatttgaa attgaaaaat 27480 ctgattctgg caaccgcctg tgtgttttct ctagccacca cacctgtact ggctaaagac 27540 aacgcaaaga agcccaaagt tatccatctt tgtaagaagg atgacacagc ggtaaacatc 27600 ttagcatgta atatgtatcg agaggctcgt ggagaaagcg attccgggtt aatgtcgatc 27660 gcattcgtaa ctttgaatcg taaggataac gataagtacc ctgggacggt aaagaagatc 27720 gtctaccagc ccggacaatt ctcctggaca tcttcaggaa caacgtttaa agtctatgaa 27780 aaggatcgct gggagaaggc acaagagttt gcaaaagttc tgatcaagat tcataaacaa 27840 aacagggtcg tctacgatgc tctggacata acacacgggg ccactcacta ccattcacga 27900 aaagtaaaac cctactggac aaaggccatg ctacgcacag tcaggatcga caaccatatc 27960 tattataaag agaaagaaga ctctcagggg gcatgaactc atgaagaaat tcttggtaat 28020 atttgtttgc attacccctc tgtgtgtgat attgtcactg tcacagccca tgtattggga 28080 acaaatttgt ggagcatacg caataggtat ggctacagcg gcctttagac taaatacaaa 28 140 caactgcaaa aagtaggaga agtagatgat aatcgagcgt aatgagaaga aggtagaagt 28200 tagtaccaac atcaaacgct atcaagctgg tatcgcgatc aatgctgaaa ctttcagtat 28260 cttgatcgat ggtatttatg aggacaagat ccttgctgcc tgtcgtgaac ccctgttcaa 28320 tgcggtagat gcacacacag aagccggatg ccgggacaaa ccgattatca tccactcccc 28380 aacggacttg gaaccgtggt attctgtcaa ggatggtggt attgggatgg actttgacat 28440 ggttactcag accttcatga tgctgggatc gtccactaaa cgtgaatcca acgatctgat 28500 cggtgcgaaa ggtattggtt ccaaggcccc gttcaccgtt acggacatgt tcagtgtcat 28560 ctctatcaaa gatggtacta aaactgtgta ctctgttcat aaagaccaag ggatacctga 28620 ggttgtgcct ctccacgagt caaaaaccat agaagaaaat ggtgttgaaa tcaaattcaa 28680 cgttgacccg gcagagactg agaaataccg ccgtgcaatt atcagttgcc tgcgttatgc 28740 taagttccct tacgagatca atgacccatt tgtgacttca tctattcgag accgtaccta 28800 cccggtgcag tatacgttca aagatgaaga atctggttgg atgctggaaa tgtactcggc 28860 ggtatctaac aatgctgata gcgttgtggt tatgggacaa cagccgtaca agtcaaagtt 28920 tctgagcaat aaccctgaat ggcctctgat gatggtgtcc attccgatcg gggattgtga 28980 cgtaaaccca ggacgtgaat ggactatcga gggtaagaat gaccgtggct tcgaagagcg 29040 ccttaagaca ttcgttcaga cggcccttga tcgccgtggt gaagaaattt accatgaact 29100 ccgcaagctt caaaaacttg ctgatgttct ggagtatatg aagcgggttg gcgggtggtt 29160 tgccaccaaa tatggttcaa agtacatcgc ggaactcttc gcagagcaca ctaactcttt 29220 gaatattaaa gagtgcgtga cttataatgg tcatggtgaa aagcggaggg tagataagac 29280 atactcttac accgacatga tgaacggctt ccatcttgta tacaacgacg acaataagct 29340 ggttagaagc aaatgtaatc agttgtttga cgtatctggc aaggcagttt acctgacgga 29400 taatcgaggc gtggcacaaa tgtgcgggaa cccattcttc gcagggatga tccataggct 29460 gtcggatttg gaaaagcgtc cagcatcgaa gtcggataaa aagtatggcg gctatagcct 29520 gtatgaacca gggcatccag tatggatcat tgagcagagt ggagctatta ggaaaacacg 29580 tatctcccgt gcggaatttg atgatatcaa atatgccatg atttattctg gtggtcaggc 29640 gcgtgggact tgtgatcttg gatctacggc gtacctttct aaccgtcatc agccagagac 29700 cttcttgtcg gatcttggta ttgatgataa attgtacatc gtacctttaa atcgggttag 29760 ttggttggat gatgatgttc ggatgatcac acaggacgac ctttataaga ttgcaagttc 29820 aaatctgtta gagtatcatc ttaaccagtt aactaagcgc tcggagtatt cttctcttgt 29880 taaagacttg aaagtcttgg gtgttgagat agttaaagac cctgagtaca agcaaaaggt 29940 taatatggct aacacccttt acaatattaa agggtattat cgagcagaaa aaactgcgga 30000 aagaatcgtt agtggacgga ttcgtattgg taaaggcctg atcaacaagg taaaagaacg 30060 ttacccgtta ctgaagcaca tcccgatgga gcattttaac tccccagagg tggctgagta 30120 tcgtaaattt attgatagca aaggagagaa ataatgagtg atctttttaa atcccgtgca 30180 gatgctcgtg tttgtgctgc aagtcgtggt atgaaggttg tagaccgtgg tgtatcccca 30240 gcggtgctgg cagaggggcg ttggatggtt gtccccaaag acagtattgg tgcttccccg 30300 gaaaagacga tttccttcga tatggaaact taccctgcgc caactgcctc tatgttcttt 30360 gcgagtcggg gagaggcccg agcattctct aagactgtac agaatgcgaa gattatcgat 30420 catgcaaaga caacagcagg acatgacaaa gaggagggag ttgtcaagga ccttggcaag 30480 cgtggtaagc gctgggaagt ggtgttcgta gtttctgatg tagaagtgag cgttactgtt 30540 cctcagcttc cagaacctac acctgtgcct attaagattt cggttgttga tgacacgaaa 30600 gctgatccca ttgtcatcat gacaccaggc aacgtttcca tcacacttcc agatggaacc 30660 attcatactc tgggcagtaa cagcgaaatc tttaacgacg tcggtatgtt gctgttaaac 30720 aacaagatcg acgaagcagt agcgcttatt gaagcgggga tcgctgcaaa agctgaagtg 30780 gcaatcgacc ttggaccgga tatgaagctg ctagacggaa ttctgtactg gcacggtatc 30840 aaacaagaaa gcggtattgc tcgccgtatt gtttccgata tcgagaccgg gaagttcgat 30900 aaccgttatg tcgagttcat gcggaagctg atgctcaatc cttcttacaa atcggttgaa 30960 atgctgtacg acttcctgga gcataacaag ttcgagattc tggagaatgg caacatcttg 31020 gcctacaagg gtcttaaacg cactgagaat ggtcctcgtg actggttcac aggcttggtc 31080 cctaactggg ctaacaccac agtcactatg ccaagaaaca tggttgaaga tgacccaacc 31140 aaagcttgta gccagggttt acatatcgcc tccaaggaat atgcccgtga ttatggtaat 31200 gtggttgagg tatctgttga cccggcagac attgttagcg taccatataa ctacaataac 31260 aagaaatgcc gctgctgccg ctatgaagta ttgacaggaa aagaaaagcc agcaggtgct 31320 cctgatgtta ttgttgtggg tgtaaggggt gctatcctgg acgaaattta tctcgataag 31380 gaggattaat gtccttagtc cacggacagg gcattaatga tgccccttat cccacaaccc 31440 ggtacactct tgttggtggt aagcgcacac aggcgtggag gtgcccgtac tacaccctgt 31500 ggcgtaaaat gttggaaaga tgttactcag acaaagccct gaataaaaaa ccgacctact 31560 ccggggttgt tgtggaagag gcgtggaaaa cgttctctaa tttcagagag tgggttgaat 31620 gtcaagatca acacgttgct tggctcgagg aaagtgggaa aagaatagtt gacaaggtgt 31680 ataattttaa tttagataag gacattcttg tacctgggtc aaaaatttac agttggaata 31740 catctgtgct tgtaccttct tatctgaata aattttttct gttgcgggat tcagctaggg 31800 gggatttccc cattggggtt tcttggcatt ctgtggttaa aaaatttcaa tcaagaagaa 31860 gaggccagca tctggggtat tttgatgacc cgttcaaagc acatcaagcg tggcaaaatg 31920 ctaagatctt ggatataata gacattcatg acagatattc gcacagtggt gtttgcgacc 31980 acagagtctc cgaaagattg cttatgatag taaaaaacat aaggcgagac ttgcaatacg 32040 gtatcgagac aaaaaattta ttaggagggt aacttgagag aggattttgg agtgggaacg 32 100 gaagaggcct taggtgctat cattgaaggc aaaaacgttt tcattacggg acctggtggt 32160 agtggcaaga gccatctgat caaaacaatc caatccctgt atccaagttc aacattaaca 32220 gtggccccga caggggtcgc ttcacttaat gttgatggaa tgacaactca tcgagctttc 32280 gggttatcaa tggggatagc cacagaggat gatggtaaga cagtaaaaac taaacctaaa 32340 aaacttttaa aaagcaaatc tcttgagcgt atcattattg atgaaatatc tatggtgcga 32400 gccgataaat tgtgggaaat ggatcagaaa ctgcgtgttg cgagaaggga gcctaagaaa 32460 gctttcggtg gtcttcaggt catcatgttt ggtgatttct ttcagaaccc tcccgttctg 32520 acagagtctg aagaaaacgc ttactttgaa ctccacagca cagaattatc ttgtttctca 32580 gacacttggg gagagataag tccataccct gtgcttcttg acaagattta tcgtcaaaac 32640 agcgtgcatt tttcatcgct attgaatcat atgaggaaag gcgagcgtat tgatgaaata 32700 gttaaattcc tcaacaatca gtgctattca aagggtgcag cactgaatgc gattaccctg 32760 acttcaacta acgccgcagc tgaacgtatc aacaaaaagc attacgacca gataccgggt 32820 gaagaggtta tttacaaagc ctccaaaaca ggagattttg cccagcggcc agttgctgag 32880 agtctacacc tcaaggtagg gactcgtgtc atgatcaccg ttaatgatca gaatccagat 32940 gaagacggtc ctaaatttgt aaacggaaca cggggtatta tcaaggccct aaggaagttt 33000 tcggtagatg tagaactgga agacggcaag gttgtagaga tcgaaaagaa tgtctgggaa 33060 aatgttgaat acttcccaag aaaggttatc aagaatggta agactgaaga ggaattggaa 33 120 aagattgttg ttggaacata cacaaactta cccattcgcc ttggttatgc agtgaccatt 33180 cacaaagctc aaggcttgac tttgccagag gttaatatag actttggtta tggagctttt 33240 gctcctggga tggcctatgt tgcctttagc agggccactt ctacaaaagg tttaagattg 33 300 ttgcgtccgg ttaaagaacg tgatattatc gtagaccaaa gaattgttaa attctacaaa 33360 gacacattcc caggaaaatt ttaggagaaa ataatggcat catattctcg tctggagctg 33420 gcagacaagt tccgcaaaga acttgaagta tggaatcaat ggcaggttcc tcgctctgaa 33480 aaagctatgg acactaccca catccaaatg gcctctcttg acgagatgat gtctgcttat 33540 gggtatgtcc ctcgtcgtct ttctaacttc ccagaagtta aagatggtcg ctttggctac 33600 cagcttgcat tccctcgatg taaaaagatt tgtcgcccat tctttatctc gttacaggat 33660 gcagttagca tccataatgg caatgggtac aaggggaatc cattccgtag gttgggggat 33720 cgcatgagtt ttgctctaca gaaccgtatt gttgagcagg tggcggttca gagggacaag 33780 tctttggaag gtggtatcaa atcaactaag aagtggatta agttctatga ggagaacaaa 33840 aatgcaggtt gaagacttca ctgacctgag taaggtaaca acagaaaagc taatgaaact 33900 ccgtgatatc gctcaagatt atcacgatga gatgcagcaa gctgaactgg aagcgtggga 33960 aagactccaa gatataattc atgaaattgt caagagggcg aagaatgttc aaacgtctaa 34020 ttaactggct ctttgccaaa gaggatgaaa ccacagaaaa tgaagttcgg gtatttgact 34080 tcacagaaca aggtcctgga catgatatcg ctatacgagt catcaatgat ggtgaatacg 34 140 cagaggcagt ggttgccctg aaacttgcgg atctgccgcc tgcggttggt gacttcatcg 34200 tcgtagtttt agatggtgtc cacaatactt ttgtggtaga aacttcagaa ggtgtgagcc 34260 tgactgttac taaattgacc ctaactcgtt atgaaggcgc agaagatgaa acatcgtgaa 34320 aatatttgta agcttattga tgatttgaaa cgcatcgcaa gtcaagcaac accaggtaag 34380 tggtggatag attcacatgg tcatgctatg gttgcatttt caacggaaga tgctggcatg 34440 gaaacagtgt ttgtgacaga cggaaatatg ggtccggttg tgcgccatga gaacacaggt 34500 aatctttcgg cttggcgcaa tgatatggat gcaacataca ttgcgactgc ctgccctcag 34560 aatgtgctgg cagttctgga atatctaagt tctggtgcta acgcgtggaa taccataagc 34620 acttatatgg aaactcgcct gcatggtgat gcagccgctt tacgtaatga tgtaagccgg 34680 aagttgtttg atgacggttg tcatagtgca gcagtccatg caattcagtt tatcgaggca 34740 ctcattgacc agaatattga attaaaggcc gaactggagt ctaaatgatc aaagattgtt 34800 ttgggaatga ggcgagagtt ggcgacaaga tcgccttctc tcaaggcaat gctggagcaa 34860 aaaagtggga attcggggag attacccgga taaccgataa gtgcatatat tttcatggtc 34920 gcgccggggg aatgttccgt gactggcgtg atgataccga gcttcgccgt ggagaaggcg 34980 cgttcgtaat taatttagag gcgagaggac ttaatgagta aagccgcact tcctgtagag 35040 atcgaattca gttatgacca ccctactgcg ggtgtcgtca ccgtcgaagc actttattct 35 100 gtgatggaag gcgaccgtaa cagtcgtgaa agcgatgtag attacaacgg tttccaagat 35 160 ttggagtatt atgctgtatt ctctggaggc aaacagatct acgttgacat tccagatgat 35220 gtcctatacc atcatttacg cgagtatatt cgcaatcttg aaattgtagg ttgcttccag 35280 gaagaggagg agttttaatg aaacacgaag ttaaagtcgt cgaattcgaa ttcaataacc 35340 acagtggtcc aaattacgtg gctaaagtgt tggcagaaca tcttgatgaa ggatatacta 35400 tcgcagggca atctgaaagc gctagatatc tgacctacac cctagttaaa attattccaa 35460 tttccatgac gggtacggta acaaatgccg atcaccaagg ggtcagtttc cactaaggga 35520 ggccgtttga agaagaaagt gatcattctt tatgattaca cttcggtcat ggcccgtcct 35580 tggttagagg ctggctatga agtttggact tttgatggtc aacattcacc aggagtcacc 35640 cgcgagggtg accttgttaa agtcgggatg tggttcttcc acgacaagac cgttcaacaa 35700 gctcaagaga tcaaagaaat ggttggtgac aatgttcaca tcgtctttgg tttcccggaa 35760 tgtactcacc tgaccaatgc aggttcacgt cattgggcta agaaaagagc agcaaaccct 35820 aacttccaga aagaagcaat ggaactttgc ctattggtag agaaggttgg agatttatat 35880 aatgttccgt gggcctttga aaaccctgtc ggtgttctct cttcaatgta tcgaaaacct 35940 gattacatgt ttgatcctaa ggattacggc gggtatctcc caaccactga tatacaccca 36000 ctatatccgc acgtataccc tcctcaggac gcgtataaca agaagacgtg catttggatg 36060 ggcaatggcg caaaacagcc tgacaagctt cctgtgaagg aattgtacaa ggacaatcca 36120 ggctggaaga agtgtggtgg caaatccacc aagactaaaa atattcgtag ttgtacacct 36180 cgcggttttg cggaggcgtt ttaccagaaa aataaatgag agggataatg ggaaatggac 36240 cggattgggc ggcgtatcgc aaaggtggca atgaaaaccc aagagcaggt tttggaagta 36300 atcgcggagg caagttgagt tatagtaaca atcgagcaga agagaccctg gaatcagtgc 36360 tgtctggcac ccgcatcatg gctgttcccg aaatgagtct ctctcttgaa gcagcacagt 36420 attttaagat ccgttctgcg gtatccccgg cggatggtat caccccggta gcaacatact 36480 tgccctatta tgataagtat gggaaactaa cgggattcaa gaaacgtgat tggacgttac 36540 agaaggaaaa gacaggacac ttttcaactg ttggtgctgt gaaggcatca tctcagttct 36600 tcgggcagca tgaagcctct atgggtgttg gtcgtaagca gatcaatatc gtggaaggtg 36660 aaggtgacgt atgcgccgca tggcaggcag cgtatgagat ggttaaggct atgtccacca 36720 gtccaaaggc cagtaaaggc gttaaagact gggcggatag catcttaaaa ggtatccgtc 36780 atattcagaa cgacgaggac attggaggtc ttccgacact accctatgtt ggattaaact 36840 gtggtactgc aaacgctgtt gatactttcg caaacaacga gaagttcatt cgcagttatg 36900 agaaggtagt cttgggcttt gataacgacg aagccacagc attagaaaaa gaaaagaaaa 36960 taaagaaagg taaagaagca accgacgatg tcgctagctt cctgctgtca gaaaacattt 37020 acgttgtgcg atatcctaac gagcgtaatg acccggatgg ctttaaagac attcgtgaca 37080 tgtatgatgc aggtaaggta cgcgagcttt atgcaatgtt taccaaagca gacgatcgct 37140 atgtccctga taagcttatc ggtcttaagg atattaccat tgagaatctt cgcaagaaga 37200 aaaaagatgg tgttccatta ccagggcttc ccggcctata taacctgacc cgtggtcccc 37260 gtactggtga gctttggaca ttgacaggac cgtctggtgg tggtaagtct acaatctctc 37320 gtaagattga atacgcgatc attgattatc ttcgtgatat gtcaattccc cgcctagatg 37380 gctggaccga gagtgagaaa gtagccatca tccgtctgga agaggatgaa gaagagtctg 37440 taaacagctt gtatgctgaa gagctgaagg tggaccctaa ggcatttgtt gctgacccgg 37500 agcagttctt aaccgaagag caacaccttg agattcacca acgctggatt ctggaagata 37560 agattaagat ctttgatcac ttcggttcta tcccgacaga ccagcttatt cagaaactta 37620 agcagatggt gttccttgat ggttgtaaat ggatcatcct cgatcacctg tcaatggtaa 37680 tctctggtct taagtccgac aacgaacgtc gagaccttga taacatcatg accgagctgg 37740 cagctttctg taagaagtac gatgttttca tcttatcaat cagccacatg aagcgtaaag 37800 aacttcagct tccgaaagat aaagatggga atctattacc gttctggtat ccggtccgta 37860 aagaagacct gcgcggttct gcggcccttg aacaactctc atgggtggtt ctgggtgttg 37920 aaccagaaga gcttcctgac cgctcccgtg gacgtgtacg tatcgtggtg ctgaagaacc 37980 gcccacacaa aaaactgggt atcgctgata caatggttat ggatgacaac ggacagttct 38040 ccgatgcttc cggttgggaa tgggaagatg gaatgttcaa gcttaatggt gaagttatgc 38 100 ttcgtcctca gagcctgatc catcaactat ccctggaaac tccggttgga aaggtcaatg 38 160 tcccggcacc tgagtataag ccaaccatcg atcttgacag gacccccgtt cctactcttg 38220 gtcctgacga tgatacgcct ttcgccccga taggattgca atacgcaaaa catgcaattt 38280 atgtaattta ataccaactg agaggtgggc gacggtacag tctagcccac cttgaatagg 38340 aggaatcatt aaaggtctgt ttatactgga taacgaggcc gatggcctgt tagacgaagt 38400 aacgaagtac cattgtactt tgctgaaaga atttggggtc aacaactgga atctgttttt 38460 agaccccgca cacccagaat atgaaagcgc tgtagccttt gccaggagca agaaggatgt 38520 taaccttaca attcgttcat acgacgagct ggaaagcttc ctgaagacgt gtagggccat 38580 tgcgtgtcac aacctgtttg gctatgacct gcgtctgtgg aagaagttat cgggcattga 38640 atatgatatg ttcaaagacc cgaagtgcat ggggacgatt ggggatacac aggtaaatct 38700 ctacgacact ctctctatga gccgtgtgct ttatcctgac cgtccattgc ccaacggttg 38760 ccctgactct gttcttaacc cggtaaccgg gaagcgagat cgtgtaggtc ctcatggcct 38820 gttggcctgg ggctaccgtg tagcaaacaa gaaagttcag atcgatgact ggcgtaacca 38880 acccttgtgg gaatacgtta atcgtgtctg ggaagacgtt ttaatcaacg agttagtatg 38940 gcaatccctg atcgatgaat ctacaggtgc tcgctggcct gatgacaagc agttcatgta 39000 caaagataaa ccggaaggga tgcggcagat caactggaag aacgcgctac gccgccgtat 39060 gttgactgat tacctgatga ttgagcaaga aattcagggt gttccattca ataagcatga 39120 agctgaaaag ctgagagacc gtattgatgt aatgatgaaa gagattgagg aagaagtaga 39180 acctcaactc ccgctcaaag agatgacgaa gtctcaacag ccaaaattcc ctgctaatcc 39240 ttttgatggt gcaggaagaa tttcccatca cgggtggaat tggttagaat acaagctggg 39300 atatccagtt aatcgtgaag cgctggaatt caaaggtcca ccgaagacgg cgtttaaagg 39360 taacggtgat gtaagtgcag caggggaaag atactgtatc cagaatggtg ttgaagaccc 39420 ggcagcgatg ccagacttca ttagaagcca gataaagaaa gagaataccc ttgtcccatt 39480 gccaccagac ctaatggaaa aggcaattgc cgatcttcgt gctggaaaga tgccagacct 39540 gatggttccg atgaagatct cgaaccagga cgacatcaag aagtacctga tccgcgatgc 39600 gggatggaaa ccaacgctct ggcgtgttaa agatgtgacg aaagaccagt tcaaaaagac 39660 ccgcgatgat gcggaggttg atggtctggt gcgtaagtac atcgaagaac ttggagagtc 39720 cgagtataaa tctctgattc ttgagcactt aaataatagt gacgcaaagt tcaatatctc 39780 ggaaaacaag ttcgaccatc gtcatggttc tgatcgtgtt tacgaggaga tcttcaagaa 39840 gttcagacgc aaagctcgtc aactgccgac ttcaccacag ttgaaggata actttggcaa 39900 gctatgtccc aaccttgaag ttatcgacgt tcacttggct aaacagattg ttaagtggct 39960 gtcattacgt aaccgtcgtt ctgttctcga cccgattgac gaggacaaaa acgacacagg 40020 gctgttgaat caccctcgcc tggcgattga tggaaaactt ccagctcgtt tctccggcat 40080 caccaatacc gggcgctgta agcacaccat ctgtgcaaac atgcctaaac cagatcctaa 40140 ggtgttgttg ggtaaagaga tgcgtggtct ctggggtgtg accgatgaat attaccaggt 40200 tggtatcgat ggttctaacc tcgaaggcat gatcgcagca tggggcgcat atcagttcga 40260 tggtggtgaa tacctccgta ttatggaaag tggagatgcc cacgcacgaa acgccgaggc 40320 atataccaaa gcctctggta cgttggtaac tcgtaacggt ggtaaagggg taacctacgg 40380 ttaattgata gcccccttat gaagtaattt ataaggtgca tccattgaat tgctgggaaa 40440 tctgaccgag taatgtcgaa gataatcagc aggtaagcaa aggcttccct cttaagaaac 40500 caagaggagg agatatggga acattttgtt gtaggatttg tggtgttgta gagttaaaaa 40560 ctggaagaaa tcaaaaagtt tgtctgtcag aagattgtca gagagaagtt tccaggctca 40620 gaactcaaga gtacagacgc agaaaggcca agaaggaagg caggcttgat agggttgata 40680 taggaagagg tggtggtcaa ccaagcggaa aagactctaa gcattacaag actggtatcg 40740 cacagtttca caagctggcc ccagtaatcc gaaaagagcg gagatattgc aatagatgca 40800 ataaggactt gctcgaagtg gggaaagatg aatggtgtgt tcatcatata gaccacgaca 40860 gaaccaacaa cgaggtgagt aactttgagc tattgtgcaa aagatgccac cagatagaac 40920 ataattgttg ggaagccttt gaaacttcaa cgactatccg gtaacggagt agggccaagc 40980 ggcccgaagc ggtggacacc ccaagtgggt gaagatatag tctgctctgc atggaaacat 41040 gcagcagttc ataagagaac gggcatggtg gtagcgtccc atgtcgaaca ttaggatcat 41100 gtatggtgct caggcagcta agattgcagc aatgcttcac atttcccttg acaaggcaca 41160 ggcggtaatc gatgctttct gggatagtaa ctttggtttg aaaggtcgta aagaatggct 41220 tgaaaacttc tgggaagcaa ctgggaaacg ttatatccct ggcctcgatg gtcgtaagat 41280 ttggacccgt tctaagcact ctcttctgaa tgctttccag caaaacggtg gtgcatctct 41340 attcgatctg gtgggtatcc ttcttcattg ggaactgatc aaacgtggct ggtatgatga 41400 tgacgttcgt cgcctgattt actaccataa gtaacattgt ggctttgtga ggtaactcac 41460 atcgaataac tcctttaatt gtcggggagg ctaagtcgaa agatatgcta atccgcagcg 41520 aagcttgtca gtaacgctct taggcacaca gtttttacgc gaataagggt taatagtagc 41580 gtgtgcaaac gagtaacccc gaaagacccg aagacaagaa cgttcagagg ccagccgaga 41640 ggcgtaggtg accaagtggc accgaaatgg ggagcatccc gaaagggatg gtgagatggt 41700 ccgatcctat gtgaaaacgt atggcaacac gtcatggtgt gggcgagatt aacgacctcg 41760 ctaaactttt ggatgaatac cagctccagg ttcctaagaa atacctgaag aagtgggagt 41820 ttgataccct ggaagaggca acagctttcg ttaaagaatg ggaagcaaaa ggccgggtat 41880 ttgatgggca tgaatggaga aaggctgtca aagatgaaaa tggtgataaa gtcaaagatg 41940 cggaaggaaa tacagtctac gagggtattt tcggagacga tgggaaaatc cacatccagt 42000 attgccctgt tggtgaaatg gttgtaaaat gtgtagagaa ggccgctcgt atcatgggca 42060 gtcctgtaca tatcacaggg gcatacctga ctggtcgtaa ttggagcgat tgccattaac 42120 gataggggct tcggcccctt ttttcatagg agaaatcatg tttccgaaca aacctaaaga 42180 agcaacccat tactttatgt atccaggaca tcctacccct ggcggcaatt gggcgtacta 42240 tgtcagcttt ttcaggaaag ttgcaggtga gtggatggtg tacactaccg ataccgacaa 42300 tgagtacccc ggctggtcat tggcttctag acgctataag aataaaagct tcgagaccat 42360 gattgaatat ttgcaagaaa tttaaaaata gtgttgacag ccgtttcgaa tagcattaaa 42420 gtgtatcaca tgaagacgag agacctcgct tcaaaataac ttcacaaaca ggagaacgaa 42480 atgaccgcaa aatatgaaac cgtaccttac gctgacttcg taaaagctct gaaagctcag 42540 ttcgctgtca tgcaagcgct gggtgcgctt tacacggtcg atgtaccgaa agatgaactg 42600 tacgacttgt acctcgactc tttcccggaa ggcaccaatc tgatgtataa agagcgccgt 42660 gaatatgact gtaactgctg caagagctac atccgtactc tgggccgagt agtcgcgatt 42720 cacaacggca agctggtctc tatttgggac gttaaagttg gtggttacta ccaagttgtt 42780 gccgatgcga tgaaagcgcg tgttgaaagc gccgagatcc gcgatcgctt cttccacttc 42840 gaaggccgcg ttggtactga gagcaacgta gctctgctgg aaaatgggaa aaccaaaacc 42900 tggacccact tccatcaggc cctgcctcgc gaactggtta aacgtggtga agatatccct 42960 tctgccctgg gtgagtaccg tgacaacgca actgtgctgg cacgttctct gaaagatatc 43020 gatatggact ctgccgaaac ggtaatggac ctgatcaacc aaggctctct gtaccgtggt 43080 gatgagaaaa agcacattgt tgctgccttt attaaggcga aacgtgcata cgacaaaacg 43 140 ccggaagatc agcgaatgaa cttctgctgg aaacaaagtg aaacgctggg taaactgggc 43200 cgcttccgta atgatgtcat cggtacactg atgagcgatc tggcagaagg tattgatctt 43260 gaagccgcag tgaagtcctt tgaagacaaa gtctcaggga ccaactacaa gcgtactaca 43320 gctctggtaa ctccgggcat gatcaaggca gcacaagaga aggttgaagc cctcggcttg 43380 actgaatctc tggcacgtcg ctttgcggtg acctctgacc tgacgatcaa caacgtgttg 43440 tttgctgacc gttctgcaaa ggcccagatg aacgtattcg agcaactggc agcgtcaacc 43500 aaaaacgcgc cgaagtcact gtcgaaagta gaagagatca gcattgagga tttcatcaac 43560 aacgttctgc cgaaagcgga cactatcgaa gcgctggttg aaggtcgtct gacaccgaac 43620 ctgatgagcc tgattgcccc ggcaaacgca ggtgctccta acctgttcaa atgggataac 43680 ggcttctcct ggtcgtataa tggcgaagta actgactcca tcaaggagcg tgtgaaagcc 43740 gctggcggta gcgtgactgg tgacctgcgt gtttcgttgt cctggtacaa cagtgatgac 43800 ctcgacctgc acgtattcga gcctggtggc ggtcaaattt acttcggtaa caaacgtggt 43860 cgctcaacgg gtacgctgga tgtggatatg aatgcctatg gcaagtcaga cgcacaccat 43920 ccggttgaga acgttacgtg ggaaaatgag cgtaatatca cggaaggtgt ttacaaggtt 43980 gttgttaaca actataataa gcgcatgact gatcgcgttg gcttcgaagt acagatggaa 44040 tacaaaggcc aagtgttcaa ctttgcatac ccgcaagctt tgggtaatag caagagccag 44 100 accgttgtaa cctttaagta ttctcgtgcg aaaggtgttg aaattgtaga cagcatcggg 44 160 catactaagc aatctaaaga agtatggggc gtctctaccg agaccttcca gaaagtttct 44220 ctggtgctga attctcctaa cttctgggat ggtcagacca aaggtaacaa acactacttc 44280 tttatgctgg aaggttgcat taaccctgac gatactcgtg gcttctacaa tgagtatctg 44340 cgtgacgagc tgcatgagca tcgtaaagtg ttcgaagtgt tgggttccaa gctcaaagct 44400 gaacactcca ctgatcaaat gagcggcctg ggcttctcgt ctacccagcg taacgagttg 44460 gttgtgaagg ttactggttc tttcaaccgc accctgaaga ttaaattctg atgaaaacgg 44520 ggttgcaacc aaccccggta actgatagac tcgttgcatg tctggagggg ttcgctcctc 44580 cagaaaatcc ttaccaaagg atatgcaatg agttcgggtg tgcgtacata actgcaaaga 44640 aaatgttgca ctcctttacg taccgggcaa ctgaacaaca attggctgcg attcttgaag 44700 aacgcagcat actgaaaaac taaaagagga gaacaaaaat atgtcaatca tcaatactac 44760 catcgcaaat accgctaccc tgttcgaact ggctacccgt aaaaaactgc gttttgcaag 44820 cccgaaaggt ctactgacca cagaagatct gtgggatctg ccgatgactg gtaataccag 44880 cctggatacg gtttccaaac tggctaaccg tgatgtgaaa gcatctgctg aagaaagttt 44940 cgttgtcgag gccagtgctg taaatggcga agcaaacctg aagctggata tcctgaagta 45000 catcatctcg gtgcgtaaag cggagatcgc ggatcgccag gcagcgaaag agaaggttga 45060 gcgtaagcgt aaacttctgg acctgctggc agagaaggat aacgagaaag atgcagcgat 45120 gtctcgtgaa gagatcctga aagagctgga atctctgtaa tctgcccgcc aaggcccttc 45180 ggggcctttt tgtgttggag gataaatgaa agtaactggc aaacaaacta ttgtacagaa 45240 tgtggaagta gatatctctg atgaagagat catgaatatt gtcaaggcac aaacaccaga 45300 ctacctcgca gatgtcctca ccaaaaaact gctgagggac ttcatctata gattaccagc 45360 agattttact ggtgagcggg ccgtgtggga aacacgtaaa agaggatatg aaccgtttct 45420 tgtacttgtc catgtagacg cctggtggga ctaccacaac aatgttggtg tggatgaaga 45480 agtcagaccg ctcaccgaag aagaaacggc aaaatataat atgatttgcg gtttgcggga 45540 ctacattaag gagctgcaaa aataattcaa aagcctcttg acttcatggt tgaggggctt 45600 tattgttatg gaagctaaat aacctggagg gtgtatgtta gaggcaatca attatttctt 45660 tttagttctg gcagcagtgg cctgtgtttc ttgtgccttc ggcgctgtct tttcaaaaga 45720 tgaaacacac cgcacggtgt acgtaggttg tgcagtcatc aacgctgctt ttacggtgca 45780 tctctggagt atcgccctat gaagctttca cattttattt atgcagtgtt aggccttatg 45840 gccctgacca tgctgacaac gttggggctt tcatttacag cagaccatga gcaacaaaca 45900 aaagaaattt tgggagcagg tttcggtatg tttatgcttg aattcttcct gcttcttttg 45960 ggcggtgtga ttgtcgatac ttccggctgg taaggagaaa taaatgcgtg gattcatgcc 46020 ttgggtgcgt ccgttggtta ttgtgattgt tgttgcagtt gtcgcctaca tatcgcttga 46080 catcgcagat aacgtgaccc ataattgcaa gcctaacggt gagcaacgcc ttgctaactc 46140 ggttgatggt gttatcgttg agaacaaact gatctgcgac ggtggtcgag tgaagtggtc 46200 tcgctactaa attctgacta aataatctca agaggagatt caaatgaaaa agattatcct 46260 agccgccctg ctcgcgcttt cttgctctgc acaagcaaca gagttttatc ctgaagcaaa 46320 cccgaatgat attaacgagt ccgttgatag tgaactggca aagtccctac tgaaacgcga 46380 cacccttgaa ttgaaaatta aaatcgcaga gcttgaagtg gaacttgcca aaatgaagaa 46440 gactcaagtt ctatacagca ttgcccttga atcaatggag aaaaacaaat gacgattact 46500 cgcggcctta tcttcggaaa gtttgcaccg ctgaccaacg gacatattga attcattcgc 46560 caggcggctt ctcaggttag tgctctgtat ctgttcctgt cctatgacca gaaattcgtt 46620 gacgcacaac cagagtggat tcgtcctaag ctgggacttg ctgatcgtta tcgtgacctg 46680 ctggatgtca ttgccgacga gggacttgac aacgtgaagg tagactacgt tgatgagtcg 46740 aatatcccag gataccctga aggcagtgct gcctatgcaa aactgatccg tgaaaagcaa 46800 ccgttcgtta agtacgattt tgctttctct tctgagccgg agtatgagtc ttacttcagt 46860 gagttcttcc ctgaagcgaa gcatgtagtt atcgacgcag aacgtaaagc tgttcctatc 46920 tcagccacga tgatccgtaa tgatccgtac aacaacttct acaacctggc gtggcctgca 46980 cgtaaacgct tcatgaagaa ggttgccatc attggtgttg agagtacggg caagacaacc 47040 ctgacaaaac atctggcgca taccttcggt gctggttgga ttcctgagat cgggaggctt 47100 atctgtgagc gtgaatacca ctccagtgag ttagcaatgt ctcgtggaga ctatcttcgt 47160 atcgcaatgg agcatcgcct gaaggaaatg gagttagctg gttggggtgg ttgtggggtt 47220 atgttctctg acaccacaaa cctgatcact catttctctg gtatttgtgc agacaagatc 47280 gactactccg atcttctgtt ccgcacactg agccgtgaag agagctacaa cttctacgac 47340 ctattcctgt tcctaacacc agaggtccct tgggttgctg atcctcttcg tttacaggat 47400 acaccagaaa aacgtaaaga aacacattct ttgcttgaca caatgatcag agcatcttac 47460 gatacaagca aggtggtggt tatctccggc agtgattacg acgaacgtac tcagaaagcc 47520 gaagaagctg tccgtaaatt gctgaatatc aaaggagaaa aagatgaacg taactaattc 47580 aagcatgaag caggcttttg gtgttctgaa gattattttg gaaaaggcac ctgaattggc 47640 ggaaggtctt caggcttatg ccaactgtcg tgagcaaggg ttctccatca tgaagttgga 47700 ctgctccggt ggagaagata attgtcgcca agtgtcattc tcagaatgtc gtaacagtga 47760 tcagatcact gtgtactggg gtgggactcg tgacttcaat ttccaaacta acatcccaac 47820 tgatgatacc tatttcaatc gccgtaaatt cttcggctat gaggagtacg aagaggtagc 47880 agactggatt attgcatact tgaagggtga taacgatgga tcaaactaag ctggaaattc 47940 tccacttctt agagaagtct ttagaggaaa agcagggatg gacgtaccac aaagaggtgg 48000 ctgatagatt tggtgagcct gccactacag aggctctctc ttctcttatc gggcatggta 48060 aagtggtggc ttgtggctgc gggtgttccg gtatgatgat cacccctgtg ggacttgagg 48 120 atattcgtcc accaaaacgt atcatggtgt ggaaaacaga atccgggaag gttgtcaggc 48180 tgacacacat gtctgatgac catctgcgaa atgccatcat ttggttgcta acagactcca 48240 accttacgga agagtacgag ggttattgga tcacgcaatg gttagtggct atgtctcgtg 48300 agctgcacag ccgtgtatct gtataatggc taaagttctc aacttttacc acatcggtaa 48360 agtgatccct gaaaatgctg agtacatggg gcgagccatg cccaatcttg gtttgaaaca 48420 atctaagttt gctaataagt tcaaattgaa taaagatggt tctaaccgag ccgaagttat 48480 tgagcaatac cgggtgtggt tgtggcaaca aatccgtaca ggtaaaatta ctattcaaga 48540 tctgcttgac ttggatggta aagaccttgt atgcttctgt aaacagccga acaaagaggt 48600 ggcatgtcat tgtgatgtga tacttgcggc aatcgaatgg gctaaacaaa ggagtcaaaa 48660 tgtctaaaga atttatggac tggtttgata aaaacgcacc agcgcatctt tatccagatg 48720 cagaggagcg tgaaatcctc cagttaatgt gttggttggc atggagagat gggatcaggt 48780 ctgtcttacc agttgtaatg gagggttaaa aatggctatt catgcaaaaa gtaatggtct 48840 actgatcggt ggtaagatca tcgaggagac actgacaggc tgggttttcc aggcaatgga 48900 taacaaaggt actaattttg tgttcaagtc agatgagaag aaccaagttt ttgacggacc 48960 gaatgctgtt ggcgaagcaa tggcttggca aactaaagtt cggtcagaaa tgaaaaataa 49020 aaagaaaaag gggcgcaaaa atggctaaag atacatggga agtatttcat gatgacgatg 49080 aaataaaggt cattgtctca ggctctcttg aggtaggttc cgggtggcga tcttacagcg 49140 acgtgtgttc agagattaat agtattgaag atgcaaatct tatcgcagca gcaccagaac 49200 tgcttgacgc agtgttggat ctgaagtata agttatacgg taacggcgcg gcgaatccta 49260 aaatcgaagc acttcttaaa cgattaacag gagaataacc atgaatacaa atctgtacat 49320 taagacagca tggaccgact tttatggctg gtcaaaactt gaataccttt ggctcctcat 49380 ctgctcggca tcgatcgcca ttgtctcctt gactatggac ggtgggttag tagagttcat 49440 ctcttctgtc accgggatca tcggggctat cctggtggca aaaggtaagc tctccagtta 49500 ttactggggc tttgtggcaa cggtgctgta tgcatatatc tccttcacgt acaagttgta 49560 cggtgagacg attatgtaca ccctgttgtt cacccccatg caggtcattg gtggggtaat 49620 ctgggcacgt aagttaaccc tctctgcgga tggtgaacgt gcggatgtca tcaagaagta 49680 cctgaccaca aaacagcgct ggattgttgg tatcgggaca ttggtgacga tcggattata 49740 cgccgagttc gttagcctgc tgaaagggag tatgccgggt ctcgattctg ccacagcaat 49800 cctgtcggtt ctggcaacct acctgatgat ggttcgttat gcagaacaat ggctgatttg 49860 gctactggtt aacactgttg caattgttat gtgggtgcaa gctacgattc atcatcaagg 49920 agctggttct gcgattttgg ctatgtgggt cacattctgg ctcaattctc tttatggttg 49980 gtataagtgg agaaagaatg gctagaaaac tatgtacggg gtgggcgagt gattcaacgc 50040 tttacggaag ttgtagacgg tatactggaa gacatttcaa atttacgtga aacaaccaat 50 100 tttggagggg gtaatatatg attggattct gggaatggtt tacaatgaat cacaattggg 50 160 tgtctagcct gatcccgctt gctatgtttt cctacatagg atggttattg tcgggagggc 50220 ttacttggaa gggaaaagtg gcctcctatg tgttttcagc cgtaatgttt ggggtaatgt 50280 tctgggtagt gacttactta ggcggttatg gaatgtataa gcgccattat actacttgcg 50340 caaagccaga ggctgtggca tcattctatg tgtttgatgc aaagaaagat cgctgttata 50400 aacctgttgt tggatttgca cctgttgatg ataatcaggt aaagactctg acaccgaaac 50460 aaatggagac tggagaatgg ctttaactcg tgaagaacgc acatgtgcca agtttgtcga 50520 gatgtatgaa gcaagcttag gggacaatcc taatctggaa gaacagttag ttctctcata 50580 tttcaagaaa aatgtagatg acctaccagt ggacttcgcc gacccaccaa gtttccacaa 50640 agcattccgg caggttgaca tctgccgtaa aggttatcaa gacatggtga tttggtctct 50700 gatgtctggt ggcgaattaa atacaatctg gaaagttttg gaagaatttt atgctaattg 50760 atgaacttgg tgttcgtagc cttgtcccag atgcttgggc agaggcctat ggtaagccac 50820 aagctgatcc tcattctgtt ttcgcagagc tgcttggtgt aacacgacag caagcgaagg 50880 tagtcggtta tgagtatatg tactctgaag agaccgaaca tgttcgggcg atcaaactgt 50940 ggcacctatc gggaaaagaa actcgatatg tttaccggaa gcttgctaac ctcttgttgg 51000 agaatggggt tactgttcct ccgctgagag aaattcttga agaggtagac cggaatgaat 51060 aaaatccgaa aatttttcaa atggttattg gggttattca gtacaccaac ggtcgtatct 51120 atagggaagg gaaacagcac ttttgttagc caaacaacca aggtgaccac aatatcttct 51180 gaagagctta atgagacgct caacgaggcc cttcgtcaag caagacaaaa caatgagcgt 51240 agattgaaaa tgtcaccccc aacgccacct tcaccgccta aaaggcgtgt ggtcgtggag 51300 gatggcggtt atcgccggag aaatgatgat gcggcgatca tcaatacaac cacgattagt 51360 gatacgtata cccatcatac gccaagtcac tcgtcaagta gtcatgactc gtattcctcc 51420 tgtgattcga gttcatcatt ttcaggtagt tgtgattaag gagataaaat gaaaattggt 51480 ttcttaggtc ttttggcgtt ggtatttatc acgcttaaac tgtgcggcgt gatcgcctgg 51540 tcgtggtggc ttgttttact accgctctac ttcggtgttg ccgttcttct tttcttcttc 51600 ctgatggcga ttatcgggtg gctgggactg gcaagtgtag gtcgtgtggc tgaaatgatg 51660 tcaagttcaa aaaagaaaag aaagtaattg acataacaag tgtaaagggg taagataccc 51720 cttcactaat aaatggagga ttgatgactg aagaagtaac ccctaccaac gaagcacgct 51780 tcctgggact agaccccaat cagttcggaa ctgtgatttt cctctcaagt gccagcgttc 51840 agatggctga ccatataaat tctgaacccg tcagaaaaga aatggaacgt ttgatcagtg 51900 aaggcaaaca cgaaactatc gaaacggcgt tggcctggat tcgtggtcag cgtaatgctg 51960 tgatgcaact gagtggagct tcaaccttcg cgcaaaatct tttggcgcaa gttgaagata 52020 tgttggttga tcaacttctt gctgtaccag ttacacaagt cgttgaagaa aaacctgagt 52080 aataaaggag agaagatgag cgtagtaaac gaatacaaag acccaatgtc cggcaaagta 52140 aactacttcg caaaaggtag catcaaatac atcagcatca aacctgtgaa gaatgctgat 52200 caagatggca ttaagcgtac ccatatccct gcacgtaacg gtcaacctgc taaggtgatt 52260 gaagccaccc acactatcag ctttttaatg caggaagttg atgcggataa taacgtggta 52320 gacccacaga gccaaggtga atggatcggt atgggtgaga agaaacttca cgccagccac 52380 acggataagg ttcaggtcaa gtttgattcc ggttataaag atattctggc tggcatggtt 52440 gtatctttcc cgctgaaagt ctctaagaat ggggataaaa cctatatcaa cggcacttta 52500 agcggtaaga cattcaacat tctggatgaa agcaaagctg gtcaagctgc acctcgtcag 52560 cagcagtctt ctgccccagc agcacagtca ggcggtggtg ttaagatttt cggtgagatt 52620 accgaaatcg taggtaatct ggcgactgtt aatgacgaga agaacggccc cggcggtgta 52680 gttctctccg atgaacagct ggcccaggta tctgtcggtg gacgaatgac tgcctttgtg 52740 gatatgtcta acggtcacat cctgaacgga ttcaaagctt atggacccgc aggtcagaac 52800 agtggtagtt ctggtggtaa aaagagtggt ggctacgacc aatttggtgt tgaaacaggg 52860 cacgccatta acggtctgaa agagttgatg ggtgctggtt ataaagtgaa ggatgagctg 52920 gagacagcta aagccattca ccgtgccaca ttggatatga aagcgttcgt tgcggagcgt 52980 actggtaagc cagtcgattc caacccggta ggtgcaagtg ctggcaacgc aattctggtt 53040 gcatgtagcc gtttcaatgc taagtcagat gtttctgaag caacgattct ggaagcagcc 53100 aaagacgtgt atacaaagct ctctgagccg ctttatacgt tcattagtga aagtgccaaa 53160 ggtgccgatc aaactccgtc acagcccgtc caggagcgtt taacgacacc tcctgcccaa 53220 gaggctccgg ctatggattt tgatgagccg ccgatggact gggacgaaga aataccgttt 53280 tgataaaaga aaaggctccc atttgggagc cttttttatt acggtctttg atagacagct 53340 acatcatata cagtccctct tccacaatag gtcacttgta gaattgtaac tgaatttgca 53400 gcggtgctga tcgtaccacc atttatgatt ttataagacg cctcgagggt gactgcatgt 53460 ccgccagttg catcctggaa cagataaatc gtagcagtaa aagcactacc aagatttgcc 53520 caaggtccga tagtcaaagt atttgtcaca tccacgttat agatgttatt catcttcgtc 53580 agatcagagc ctgtccctcc cggtgtccag gttgtccctg cggaaggcgt ggtaacagaa 53640 ccgggggttg ttcctacgaa attcgcagtg accttcggag ctgttgctgc acctgtaata 53700 acgagggatg caccttttaa agacccgtat gcctctattg tggtggttgc taaaacggat 53760 ttagggttaa tgtcctttcc attgacatca attgaaacac ccgtcaaagt accaagtacg 53820 ttaaggttgt ttacggttgt tgtgcctgta ccaccattat tcaggttagc gtttccagcg 53880 actgtaaggt tggtgcttac cgtagctgcg ccagcaactg cgagcagacc agtaatggat 53940 agattccctg caacagagct agccgccccg gctgtaaatc ctccagttaa tgtgctgttc 54000 ccattcactg tcagtgagct taccacacct aaattctgaa tagaggcact tccgagagtt 54060 gttacaccgt ttacagttag atcagaccct atctcggctg ttgtcgttgt gacaatagag 54120 ttggggagaa tatctaagcc atcaacacca acattgacac cggacaacga accagttact 54180 cttacgtttt caagttctgt agttcctgtt accttaagtc ttggttccgt agaggtcttg 54240 gaagagttcc ctcggatata cacatagtcg aaggtgttat taccgacacc agttaatgac 54300 attgtggtgt tgtctgcact tgctgtccca ttcacaataa ctgcggaagt cagattattg 54360 gtttgaacag aggtcggaga tatgatagtc ttcagatagt tagaggcagc ggtgtagtca 54420 aaagaaagag tggcagtttg tccagataac gaaattttct ggaatttacc aagcacacca 54480 gaggcatcaa tcgtcccccc aaattgtgac gtcccagaaa caaccagtgt attaagggtt 54540 gaagcaccaa ctaccgtaag agcagcataa cttggagaag acccagcaag agaattgatc 54600 gctgctgcga cagccaagtt gacaaatgca gttgtcgcta ttgcaccact attacttccc 54660 tgagcagggg taggcgctgt cggagaaccg acaaatgcag gggtattaag aggtgcaaat 54720 ttttcagaaa ctacaacgga gtcattataa actttccaag cggtgcttgt ggacggatcg 54780 gcaggtaaag tgacaggtgt agatggtgac gctcctgggg cataccacca gaaagtccct 54840 gctgaattgg taaaggaata cagttggtta aaaactgttg tctgtgtccc cgcagcccaa 54900 ggttgtggtg gtgttttaaa atacacatta tcaagaagcg ctttacgtaa tgttggaatc 54960 gtgctaccat cttctacaat aacagtgtcg atcgccgatc cgttgaccac cttatggaga 55020 cgctcagaat cctcgataac ctgatccaca gcctgttcaa attgtgttgt atcagccatt 55080 taaggtctcc ttatttaatt tcttgtttat cttcatcttc cgctgccttt atagctaaac 55140 cccagcgaag tgagattagc ttgcttataa gttgtggagc tgctacagta ggtgcatata 55200 cccacatgta ccattctgta agggttcctt taaatcccca gtacaggaaa acagccgtca 55260 tggatgccag tcctatattg ctccaaaact tggtatgtga ggccttatca gggtctatag 55320 gggacctgac taagtccttt aggaacttca ttattcgagt tggcatttta cctcgggggt 55380 caataagtga agaatgataa tgccctggca agcaccaaca ggcttatgac agttgcagtt 55440 tttatccatt cctttatcgt cgtgtcttta aaatttgcac aaagtatgat aatttccatc 55500 caagtttggt aggaagaatt tattacaaag tcaaagagtc cggggattat taacggaaac 55560 tgcatggata ttatctggca gaagagaatt ggtactgcta cagagagtgt tagctttttc 55620 ttccatcccg ataatataca cgcagcacca aagataaaag agatatccag gaaccaacaa 55680 agattgaggt aaagagatag atcgaaaaac tgggtgtttg aagaaaacca ccatagaagg 55740 gtattctcaa gaaagatatg gaccatgcca agaacagaca tgatccttat acctttgtcg 55800 gaatgaaaca acaaaataat aaagcacagg aaatagaata ctgagcttat cattttgcgg 55860 atctctccat taacatctgg aactgtttgg tgagatctgt tcttaaatca ccaacatctc 55920 ccttgatatc tcttctaaga tctgaaacat catccctaat cgcttttagc tttttatcta 55980 agatatcatc cagcttttct ttagtgacca tttcggccct tatacggatg atatctttat 56040 caagctcatc aaggcgctct tgagtctttt tgtaatccga gtacgttatt cttaggactc 56100 caattaggac aaaggtaata accccccaga ccgccttcag gatagcaaat aggtcaatag 56160 acatagtgcc tccttaggct gtctgcggaa gttctggctg agggtctccc ttggtccatt 56220 ctctgagatt aatgatatat ttcttcatat cctcaacctt atcctcttca cccagtgcag 56280 cgtaagttga tagcagtatc gcggcccttt ggaaaagtcc ttgtttctta ttttcaaaga 56340 ttctgtcttc catccactcc actttttcga actcttcacc gttaaagata taagttctat 56400 tagagaaatc acttgggaga gaatctacaa gacgaaaata acaatcttcc gggaagaatt 56460 tggtagggtc cgtatctacc atatagacct gaccgttaga atcgtattga atatatagac 56520 ctttttgttt ttcttttaat tgcgatacaa aatcgtacca atcttggccg ttctcatctt 56580 ttagatataa ggcgccagga actgcaagct tttctggaga atatctaacc catttcatat 56640 cagttatttt cattaaagcc ccactgtata ccaaatgcca tcaagagctt tctgtaaaaa 56700 tctgaacctt atctcatcaa tatcgtgcag ataaaggtct ccgctggcgt tcgcatcaat 56760 caagccagtc aatacagagc cgtcaggtcc acgcgcaaaa cgtccacctg aaccataatt 56820 ttcaaagtta acgttgactt tgttttgctc accgctccaa cgaatgtcag aaaccccaat 56880 actaatattg acatctccat tagcatccgc tgccgttcta ttcactgcac gaacaatgga 56940 tcttccacca acaattgcgt tgttagagtt tacgacgaga ttttgtaaag tagctgtccc 57000 attaacacca aggttggctg tctggatatt accaccatta ttaatggttg tggaagaaac 57060 tgtacctgtc gtggtagttc ctgttgccgt aatattccct tgcaccttta gcagcgcaac 57120 gccattagac gttgcattaa gctccatcat gttgaatggt gataatgtac cagagttgtt 57180 tacaggaaca aagcggaacc tcatgatatc tacagttggt tgccccgctg ttcctacatt 57240 atcaccaata acgaagtcta aatagacttg atccgtaccc gttgtggtgg tgatataagc 57300 ggtatcgcta gaatcagagg ggaatgttat tctgggtact gtcagcgccc cagtcattgt 57360 atcaccagaa gcatttacat accgggtatc actttccccc ttgctgtaaa catctagagt 57420 gcttcttgcc gttgggatat cagatacatc gctaaggttt tgatcttttc tcagataatc 57480 attagagagt cctgggatct gctcttctga gatgtacgtc atccaccagg tcatcatgtt 57540 aagaacatag ttaagttctt cacaagcggg cttctcaccc aaatcccaac ccttatccca 57600 aagatcagcg ataggggaga ttttatttgc agtatgggca ttaggtaaca cgacgtcact 57660 ttcagcccat atctgaagag gaatagtagg aattgccatg attctccctt ataatagtgt 57720 gttctcttct tcggaggtat agataagact ggataggcca ccagtccctg ttcgcgatgt 57780 gcttacagac ccaaaaccga ttgcatagga atcgttttta aacccaaaag gtagcccttc 57840 tgattttacc agtcgaaggt acgtaggcat agggagcata tcttttattt cttgtatagc 57900 tgtttctatc tcgaaacaac tattaaagat attgatatca aaacgataat tatcaccttt 57960 gtaagtggta aaattctcgg ctccgaagag ttgcttcagc gtcccaatta cctcaggtct 58020 ggtcccgtgt ttagctgtgc ttgagagcag gattgtgata atggcacgat aattcatatc 58080 actcaagcca tttctgtcaa tccccacttg agcaccaatc tcatccaagt tgacccctcc 58140 ggcattctgg aggagacgcc cttctgcaag attgaccatc atctcatcta cagccttcat 58200 tcgttccaaa tacacggata aaaattttac aaggttttct ttttcccgta aaaagtcccc 58260 cggcaggtag tcaataccgt ccgaaacgaa atcatccaat ggatggatgt ggttgacatc 58320 ttttatcgta tctgccataa tccctcttag attatctgta ggaatgtaat attatcagtg 58380 tcgatagaga atacttcatc cagccctgca acaacatcag aggttgtata ggaagtatca 58440 ggatccccga cgttcttgac atccacataa agttgtgtaa atctaccagc agagatagaa 58500 gaacctacag cagatacaag ctggatattg tataaagtgt cagcaatgtt aagcgggtca 58560 ataacacctt tgagggcgga ctttatagta tcctgttcag tggttgagag gacctttcct 58620 ttataacgga cacggatagc caaatcccgt gcctgtgctt tactgtgata aattcgttct 58680 gtctgattat cctcagtagg gacatcataa aaaacgttac cataggtagc gttagacaaa 58740 gcaattgaat tataaagtgc cttgctaata tcttcagtag acccaccata caccacggtc 58800 tcaaacttat acggtggtat tccattctgg tctgtagtcc ctgtgttatt tgagaagatt 58860 ttaaccttac ttacaccact caccccaagg acagcactca ccaccgcagg tctggtcgca 58920 gccgcactcg atgctgttgt gttagaagcc ctaaccttgt attcggtgtc ggtctcaaca 58980 tctgtaccct ctgtgaaggc attcatgttg ttaaggctga tgaacccacc cggtgttggg 59040 gaaatcgagg ttacggtgtt tttctctctc gacagttcac ctgcctcaac agcaacaaca 59 100 tccattgtga ttgtacgctc accaacaatc ggtgatgttc tgaaatcaac acggctgtta 59160 agacctatca tctcaagatt tgtgtcatac ccaatgtaca atgccccgtt ttgagaatca 59220 atgatgatcc tatcattatt aagctcggag gtattgttga caataaagct cttgacagag 59280 gccatgaaag tgttaagctg agaactatta ggggttttat tggtcaattg aagagttgtt 59340 tgacttgttg ttccggtgtt ttgattattg atctggaaac tataagtacc tacaacccag 59400 tccttattga gaattttttg tgccagtatg ttaccagcaa gggtggtgtc gtcatttaat 59460 acaaatgtac cactatcaag tatatatgtg ttttgggcat ataccatgtt gtaaggaaca 59520 gtattgttaa ctgtcatctc aacagaccct gaactttttg tttttcctcg acgataaaca 59580 cctcttctgg aaagcaactc atcaaggtaa ataccttcag ccccagcaag ggtctgagcg 59640 gaatagatgg atgctgccag aaggataatc tggtattccc tttcgttaaa aatggttgtc 59700 aacttgtcag caattgtatt agcttgcgtg ttgaaatttt caccaaaagt tctaatgaga 59760 gtctgttttg tgtctgcgat aaggtcatca agagagggga tagtaaaacc gtaatcgctc 59820 aatccatatt gagttgccaa ttcgtcctcc tttcaggacc atgattcttt tgtatatttt 59880 accatacgtg gcagtgtttt gcaaataaac ggaggaagac cataaatgaa aaaaccaccc 59940 cggagggtgg ttagttgccg gacaaagaat cttccaagac tgaaagtcgc ttgtccaagt 60000 cctcctgcat tgcaatagtt gcccgcaata tccagaacag caattcctct tttctaaagg 60060 catactcctc gcctgctggc ctgtcaccat ctgcttccca cttatcgtag cagaatgctg 60120 aatatttggt ccaatcaagg ccgtgtttga gcatgacctt aatagcatct tgcacagtgg 60180 ggccggaatg aagtcttgcg tcacctttct cagatgagta tttagccaac cattgccaaa 60240 ccgaatctaa tttcccaatc tcataaaaag ccctagtttc tgcgggggag atctggcgaa 60300 gattagtctt ctttttcttg ttagaggtag agattacgct gtttactgcg taaacttgac 60360 tccacctcag ggcggtggtg ccactagata tcagattgtc tgtttttgga gagaacgcgg 60420 ctgaagtagt agatatctgg accccataag acctttggga aggacttaag gaaatcttgt 60480 ttacatttgc cccgatctca tccccagagg aagagaaata ataattaccg gatatgtttt 60540 gtaaactgtt cgaaagactg tcaagagctt gttgaacaga ggatcctgag tgtgtcccta 60600 caacagaagc ccctgaggaa cccgttattt caaccctctt aaggatacca atatctgtaa 60660 ttaatttact tattgtagtt ttttcagtgt ctgtggagga ctgaatgatt aactcatccg 60720 tctccaacac cgaagatctg tcagaaagac ttcttatctt tattacagag agatcagttg 60780 ttgccatatc ttaccctcac ccgcttaaat atatgactgt cgaagtatga tctgccctcc 60840 tgcaccactg gttataaatg cagtaatttt attcaggagg cagatcaaag aagctaaggc 60900 tatcaatttt catgacagct acagttgcac tcccgttaaa ccgtcagtcc gtagtttttc 60960 ccccaggcgg atatccagtc atgcatggag gaaatttcag aatctgtcag agcgcggttg 61020 aaaatgaata cgcacgcgat ttcgcaatcc tctactgcgg tatttgactg accattcccc 61080 gtccccacct tgattgtcac gtctgagcgg gtggcccagc tcagtccgtc agccagcgtc 61140 agagaagcgc tcagattctg agtcagatta tacccggtgt tgacccgccc ggagatacgc 61200 tgtgccattg cctgccagag gttatctgta gagccgctgg caataggtat ggtcacgttc 61260 tggaatgaga acgtgttgct ggcgtttttg gcgatggcat gagcgtacag gtttgaatcc 61320 tgcaacgtca gcaatccgac agcgccccca ttacccgaaa accagcttgt cgcatagcat 61380 ttagccttgc cagacagcgc cgaaatacga cgcttcgcta ccgcaaaaat cgtgatatca 61440 ccagaccatg agtagcccgt atcaataaac gccgtattat tgaatgtgta ggagtggtca 61500 gttgttttta ccggagcgcc agctttcgtc agaaggtttc cagtaccgtc atagtttttc 61560 tccgggctat ctcccaccat cagcagggcg cgaaccagtc ccgatttcac agggatattc 61620 actgattttg catatttagc gacttcggcg ctatcgacaa ttaaacgtaa tccagacatt 61680 acagagtcct cactgaaatt gaatatgacg cagagcgatt gaatagcggg taggcgttgt 61740 taaccagcgc ggtgatattt tccccggcat ccagtccgta ccctgtttcg tatgtccatt 61800 tataaatagc tgcctggtcg tcgctgtctg cgatattgtg cccacctgca tgattcgcat 61860 caccaaggac gacggttaac gcgcccgatg gtgagaaatt aggcgtgatt ttcatcactg 61920 tgccagaggc gatttcaact gtgatagccg aaccgtagtg tgtaccatta tcgtcaatca 61980 cggtaaagcc gtaatcgttg tggtcagtaa cggcagtccc tgtatagaac ggctgtttga 62040 caagcggcgc atacagcggg ctgaacgaca cgtaaatcgc ctggccgtcg tatacagcgt 62100 cgagtggttt gaaggggtta agatttaacc cggatactat ggggtaaatc tcttttgcat 62160 attgacaacc cgcccagcga tagctgttcg cgtaccagtg attggcaggg cgtggatacg 62220 ggaactcgtt gtgcaggaaa aatgcgccac ggtctgtatc agtgatgcca atctgcgcca 62280 tttgcacgtt cagtttctgc gtgttccccg catacatgcc cccggtttga taaacgaaaa 62340 atcccggcgc ctccttctgg cctgttgctg caatacagtc agaaatcatc gatgatttga 62400 tatcgttgag atggccaaga tattcagccg ttgtcatccc tccggtatca ttttcaccct 62460 gcatccagat aatgcccgcc acctgcgtct gctcatatcc ggcagtttta gctgcctcca 62520 tgtgcccctt caggcaactc agccagcgtc cgtaataatc ggttaactgg tctcccgtca 62580 ccgggatagc cgatggggag gaaagccccg tgttgacgga tgtgggtttg gcaatctggt 62640 aaatgccagt tgtcgcaccg gaggggaccg ttatacgacg actgatcgga taaactgaac 62700 cggcagcagg attggtgatg gtcagcgcag caactgtaga gttggatagt gacggcccgt 62760 caaaacggat attgacacgc accgtcccgg tgatggcggt tgggaaataa acacgaccag 62820 tcacctcaat aacagccccg gcagtcacgt cgaatttcgc gctctcaacg tatgacgagc 62880 cagaatacag aacgttcacg ccgtcaacgg gcgttaccgt cccggcgctc cagccgctcg 62940 ccgagtttgc gaatgtgggg ttgcccacga cattgtttgc cgggtcagcc gccgtccgct 63000 tcttcagcgc agtaatggat acgccaacag tgccacagca tgaaccggca aacgtcacgt 63060 cggtatcgtt cgccagccct ttgctgcggt tatgattatc tttcaaagtt tccagcaggc 63120 cggatagaat ggtttcaccg aacgtggtgc tgtcagtgga gtcatccgca gtcattgtgc 63180 catcgtcttt ctgacgacgc tcacgcaaag gatagtattt attctcacca ccaacggggg 63240 aaaatgcgtt ctgaatgctc gtatttaagt ttgtcccacg cggagactgt cccagcatta 63300 aattaccgag cgtgctatca gtgcgggtca gaatcccctt cgcggctgtt ccaagcgtaa 63360 atgactgccc gtagacgaac cagaggttaa gtccctgtct gataactgca acagggtgtc 63420 gtttcagatt gtagttctga gcgatatacg ccgcagcgtc ggcactgagc cacacgacat 63480 catctgatac cgatgacgga gcaacatcgc tggcaatctg cgatatcagg tcaacaagtt 63540 cgacctcaag tccgttttta tcctggaaag acaggatact ggattccgat gcaaggactt 63600 taacatcatc caggttcaaa atatcggcgt tcacttgggg gattttgtca acaatcattt 63660 ctatattgcc ggtgtcctcg ttaacgtaaa acgaacagac cgagaagccg tctttcgtgg 63720 cgattgacac tgctggtgag tctatggccc cagtatttat caggctgtcg atgtattcct 63780 gagacggcat ctttcgcccg gtttctacaa gcgcgccacc gttgttaatt acctcaactg 63840 caagaacact atcaccagca taacgataat aggcagttga accaataggt atatttcccg 63900 catctgcgtc tgcctgtgcc gcagccagcg tgggaaactc gcggattgtc cctgttatgg 63960 ccgctgttcc tggaactcgc gcaacttctt gagcaatccc tgcattattc ttgtacactt 64020 tgaacgctac agagcttccg cttccttgag ggacttggaa atattgccca tccgtagttg 64080 cagcaagacc ttcctctgta gaggcgtata ggtttccaaa ttcagaagct tgtaatgtgt 64140 acgcttgcgc ctcatctctt gcctctattg cctcatctcg tgcggcaaga gtttcatcta 64200 gaacacttaa cccacctacc gttacccatg cagatgttga aacaccgcct gttgtagacg 64260 gcgtggagtt tgctggtact gtcttgggga atgtacctcc ccatgtgtaa cattgcgccg 64320 ctgcaatatg ccaaatagcg tcggttccat aggttaatgc tgcgccatcc tcgaaagaac 64380 cttctaccaa agttagccca aggtcatgga gtgctcttct ccataattct ctctcgtttg 64440 cacgggcagt gtcaagactt tgttgaacat ctgttccatc agaggtccct ataagcgaag 64500 caccgccgga cgcagacagg tcttctttgt tagccaagtc caagtcagag ataacttgag 64560 agacagtggc ctttttggtc ttatctggtt gttctacaac gaggtagtcg tcttcaacta 64620 cctgagttgc ggagggtagc tccgcaattt taattgtttc taaggccatc ttttatcctc 64680 caagaaattc gtctgaaaca gtacatggtg actgtcatat aattgttaag gccttgcatg 64740 gcgaaggtgg aacgattaca tgcgccacga cagatttttt tttcactaac cgttacaggc 64800 cgtagttggt gtgaacgtag taaataccat ttagtgtggc ctcttgtctc gtctaaggat 64860 aaatttttag tgattacatt actgtaacca gccaatgtta ttacctgaac gccccttgat 64920 atcaaggtgg gtattgcttg tgccagttcc ttttgcattc gtagggattc caaggtttat 64980 cgctccacga cgacttgacg gtgggctagg cggtaacagc gcatattgtg gcttcgccca 65040 ggagttgccg cttaacgtag cgagggcgct caggtcaggc gctgcgctcc acgcatcaga 65 100 ccagatgatg ttattgttga ggataatttg agacgctggg gcaatcctac tgttgcccgt 65 160 agacagttgc gcaatgatgt ctgacccgac catccatttg cagtagaaaa tgcagttttc 65220 caccgtcaga gatggaatag tactgctctc agtgtcgcac gcatttgttg atatcagacg 65280 acgctgcttg acgctggacg tgtcaataaa cacacaattg cgaacggtat tattgaactg 65340 gttgcggtgg tgagatatgg aacacgcgtc gtttgttggt gtgccaatct gcccttgcag 65400 tcgctgaata ccatcgttga acgcgaaaca atattctacg acgttattac cgctgccctg 65460 cctgcgggtg taataaaact caaaattgct catcccggca ggaggagctg cctgtagccc 65520 tgcaccatca gaagagacaa acatcactgt acgggcgcac cctgtagagt aaacatatct 65580 gacaacgtta tcccagcaca tcccgtcgat atcaactgcc atattgtcag ttgccatcgg 65640 gtacgaaccg tgaacctcca gtttttcaaa cataacccgg ttacagtgcc acatccagaa 65700 aggtgcatcc cacgtcgcca caccagccga ggtgaactta tcccagcggt acgaactgta 65760 gtagcagtca cgaacgcagc tctgccactc gtcatccgtg tatgcgtcgt ttttgctggc 65820 gcaggtgtga attaatgcgc cttcttgcac gacgttagta aaagagcagc gcaaaacttt 65880 tgcgccatat gttctgctgc cgtcgccacg gttatccgta gtatcggcag cataggtgtt 65940 cccgcgaatg taaacccccg cgttaaccat gttaaacata cagtcttcta cgctgagttt 66000 atgcgctggt gtggcagcgt tatcatatgc cacagcgaaa agctgtacat gtcgcccaac 66060 ggtgtttttc tgcggattac tgacagagta cgcattacca gtgaaataac agtttttcac 66120 atgaacatcg gcgaccccat ccgcgccacc agtacattgc aggttaacgc tggttgctga 66180 cgcccgaaac ccatcatctc tgtccataaa gtgaatgttc tgtaccgtaa tgcgccgggc 66240 ggcccacgat gccagttgcc ccgatgagtt tgaggtggac agccattttg gcggcgggcc 66300 atccccgtat gtgtcaaaaa aactcatttc agacgacgtg ttcactaacc tggcattaac 66360 ggcctccttc aacactgtgc cgcgcctgat tagaattgaa aatgggtagc tggtgattgc 66420 cgcaatagca gcagtaacag ttttaaacgc tgatggaatt ggtttatttt catcatcaga 66480 agggtctacg tataagtatt gcatttgtaa ctcctgttaa gccggctgaa cgtgtaggtc 66540 aacccaatcg gaactgctaa tgtttaccag tgtcccggcg ctcgttctaa cttcgatagt 66600 gaaggtattc gtgccttgag atacgatgtt aactatgtac ggaggtgttc cgaacgaggt 66660 tcctgagaaa ccagcaggag ggcaaacctt ccagtggtct ccacgtaaat tgcagccgct 66720 gataacgtac tgacctgttg acgggttggt gacagcaatt ctcgcttcct gccctttatt 66780 cgccagatga tatggtcccc ctatcgcaaa aaccccgtct gataatttat cagatagtct 66840 gtaagtcata tcaccggaaa cgcgaactac agttcctggg gaatatctga tctcaccgtt 66900 attcatcctc acatagaaac ggtctgttaa cattttctct gcgaacgaat aaaccagatc 66960 gttgggagta tctaccgtta cattattccg caagtcattg tagtaaaacg tcactacatt 67020 ggggttggca acattaatcg gtgtgaatga tattttttgc ccgtatgccg gtaatcgcag 67080 gaatattttt gcaattttat tatcggggtc attaaccaat cctactgctg gcgttaatgc 67 140 tgaatccccc cagcccgact gactgccgtg tagagcagtt acctttagcc attgatagat 67200 actaccctgg ttgatgatgg gggcgttacc aagtgcctgc gggttaaacg tgaccatgta 67260 aacatttgat gtatagttta catagttacc cacggacaga ataccggaaa caacttttga 67320 tccaaaccct gagtaattca catcaaacaa gcgataaaga accggtgatg aattttcaac 67380 tgttgggcat tgatcaatcg ttcgttgcaa tgacatgcca atgtcgaaac tttttaccag 67440 tttgaacatc tgcttatcga gagatgaacc ggtagggtat cctaagtcgt taaactgatt 67500 gggactgaca acgaaaaaat cacagatacc attggcatta gttgtaataa gtattcctgg 67560 cgttagatcg tcagactcgc caccagccga tgggaaccga acgatcttat cttcaaatcc 67620 gttgttaaaa tatccggttc cctggacaat tggagtgcca acctgtgcag cagataattt 67680 accgtcaaca accgcatatg tctgaatacg tccgcgctca tctatgacca gtgctgcttt 67740 attattcggg ccgccgaata ctattccagc aacgcctgcc gggtcgcctg gcatctggtg 67800 aatttcaaat tccccgcgct taaatatacg ttcccagaaa gactgattag cgtcgccaat 67860 gctttcagcc ccttcagcag aaaaaaaacc gccaattttc gtatagccat cagactgcgc 67920 caaggccacc agcgttgact gttcaacggt attttcaaga tgatttagaa cttgaaataa 67980 agttgccttc tttgtatcat ctggttgatc aactacgatc aggtcatctt ctgttagagt 68040 gcccgcgctt ggcaactctg aaattttaac actctgtagc atcttatatt tacccctctt 68 100 cttaacatta gtacatttta ccacaaactt caaagattta aaagaacaaa ggtctgccgc 68 160 taggtagcac agatctaaaa gaaatctcga attgtaataa tttttatttt atggtgttta 68220 tcgtcttatc ggcgggagtg actaccgggt tactttttct ggttaagaga gatcctggcg 68280 gtacagggtt tgccatatca cccgcccaag tattccacca agttgcatca ccagtcttag 68340 gtaatctaaa attgataagg tagtataact tattccccca aggtatccaa ccatcatctc 68400 cgcaaagtgt tgttgtttca gggtttggcg tcgggtagta gtaatcatca gcacccacga 68460 aggctattct tacaatctcc tgctcttttg ttaagacttc aaaaaaggca gaatagcttc 68520 ttgttgtatg gtccattaca gactggaaat ctgcaatttc taaaacatcc ggttcaagac 68580 gggttatttc ctttatctta ttatcaagga ccgtcttcat aactttttta cttatgtagg 68640 ttctgtatgg aaatccaaag gtctcatcaa aataccaatc ccctgcccac acattaaacc 68700 ttagccataa gcgctgtcgt agacttactt gattggattc tatcaactga agacctgtag 68760 aaacatcaag atctccagta acagggtcca tcaagaagtc agaataaaga gttgccatct 68820 attcccctca tgcatttgga gcatcggtat tgttctgacc accatcatct gtccaagtat 68880 agtgatgtgt atggcgaata aaataatcat aaaaatcatt catgtttaca ccccgcgcag 68940 taataatatt gccatcaggg gtaacttgag caccattcat cttaatcgta ccaccagatt 69000 ctgctgtcag gtttgccgca ccattatcga acttgaaatt cccagattgg tcaaccacta 69060 attttcctac tggcgtctcc aacgtgaaat cacccgcagg cgtcattgag aaatgcacct 69120 tgtcgttcca aagttcaaca ttgtctggat cgatcgtcat ggcattccca tcgctgtgaa 69180 caccaattat cgcccaccca ggaaacatat tgtgtgttgt ctggtcatta ttatcattct 69 240 cattcctttc tgagaagctc agacccacaa tatcaccagg tttcacagga atcgttaggc 69300 gggcttttcc tccattacct gaaggcattg ataggggaac atcaaaaaca gagccatagg 69360 catccacagt cccatctggg aagtttgtac tcgcaagggg ctgaactgtt gcagacggga 69420 tgctatagtc cacatcaact accgttgccc ttagccctgt gtgaatatct ctggcctgtt 69480 ttgcaaacca ctgattaagt gctgcatcca tacgggttat tgctgccatt aggcctccac 69540 aattccacca cgggtttctg caagtcctaa ctctgtgatc caatccccac cttcgagctg 69600 gcctttgtga gttaagtata caaccttgta aaaacctgtg tatttctggc tctttaaaaa 69660 tacagttgat tctggtatga tagcaccatt catttctgtt actaccacca acccagcgtc 69720 ttcttttatc tctgctgaag tgggtacgtg gggcttagat gattttctct tagacttggc 69780 ccttttttcc tttctcctct ttgcaggctc agggttctgt ggcgttggtg aatcatgcat 69840 accagattcg gcactgatct caaaaactgc cctttgaaac cttttccctt gcgtggtcca 69900 atatacagca ccatcttgaa cactgaaagt agatcctgta ttcttggcta atctctccaa 69960 gttatttgcg gcgaggcccg taaaggacat agagtgctga agcgtttggt cgccaaactt 70020 gacgatcttc ccaatgggga gcttcatatc agaagcaagg tcactgacta ccgtgtctat 70080 tggcgtacct ttcttataag agcgagaggt ctttgccgtt ttaatattta ctgttgcatc 70140 cccgaggatc atctttgtct gacgggtatt gccgtcccac ttatcctgaa caaactctac 70200 ggtcccagaa aatatagtct gattctcacc atcaaacccg gcctcaagaa cgatcgcaat 70260 ggactcacgt tggttagcat cgaggtagct caccgtctca tcggagaggt tgtagatggt 70320 aacataacct ttattaggct ccttcgagtt gtcttttttg acctcgaact cgatgtttgc 70380 ggcaccagtt tcattactga tataatacgc atctttagca ttctggttgg tatagtcaga 70440 tatattggta ggcttttcac caacatacac tggtttacct atcgtcagct tataggttct 70500 tgttctgtaa gcaggcattg tttactcctc atcggttatt acctcatcct caggagacga 70560 gtaaagtagt tgcaagtctg acaaaaatcc aatattgtat ctccctacac gtttagtgga 70620 ttgagtaaaa gaaaatacac agaggtctcc tgccggtata ttgtccaagt attggaatgg 70680 ctgcaaaaga ttaaaaattg ttgtcagttt aaaggaaatt gtaggtgtgg aaccgacatc 70740 accaaagtat actaaccaag actcgtctct ctcgttccat tgaaaacgca tttcataagt 70800 ttgactgtcc agaaccacac gcatggtctg gtccgcaaac ccatctatgt cccaagtgaa 70860 tgttattttt gccattagtt acctaccacc ttgccataat caacaacatt accgctgagg 70920 tcctttaact tgccatccgg ggttagtgta cccactttct catcttgcat agtcctgcct 70980 gtaacaccta attttttagc cctttcttgc caactatctt gattaggccc agcaaacttt 71040 gttctccttg cagtgacgtc tacttcgtca tctgtagccg aagactgaac agagcctttc 71 100 tgctttgttt tccccccaga ttttttaggg tcggtatata ccgtggctaa ggctgtcttc 71 160 ccaagagtaa aagtacggaa ctcagtaaac tcaagttgaa acaccagcgc tgccccatct 71220 gaattgctgc ggcttgcttc caaagaggta aggatataat tttcaatgat gcggtcttcc 71280 gttacaagcg taacgatttg gcggtcagtg atgagccttt ccaaaacctc caaggccttt 71340 tctgggcgtc gggattctac cgggttgtta gggtcggtgt ctttgtcgat gtagttgttc 71400 tcgatcatgt agagtggcga gctattgatt ctcgcactga aagagaattt cccatcctca 71460 ataacgccgt ggtcactata ttttactttg ttttcaacag cgtatgatgt cttgtcaact 71520 gtccgggtat aagagtgatc ctcaacaaca tcaaaaagga ttgcaatgtt atccgtatag 71580 tttttattct ttagttcaac gtttctgcca ccgttattaa gtccgctcgc aaacaatgta 71640 tattgaactt cactactggc attctgagcc gtagagactt tttgctcaac gtttgctgta 71700 gccttacctt gttgcggttt ggactggttg cttgctacaa ctgccataaa gcctcctcaa 71760 taagcttgtt atgattttat cataaatctt caaataaaac aacgaaaaag gggccgaagc 71820 cccttgtatt aatctgggac accaaggatc aaattgatgt tacccatatt cgatgcttcg 71880 atctgttggt caatcatatc cttcagctct ccggcatcca gtttgatagt tatctcacca 71940 gagacaggct cagtagggat aaccattggg ggggttggtg ctgaggttgt tgctcctggc 72000 atcattcctt gattttgcaa ataatttagg cgggcttttt catgttgtgc tcctagtgat 72060 ctccaccagt tcatgatatc atcaccgaca gtgggtttat tcgtattctc ttcaaccttc 72120 ttatagaagt ctggttgttg agtattttca tatcccatat caagtgctgc ccaagcacca 72180 agaataccta atcctgccgc acctcttctc catccaaatc ctttacggcc tttaggagat 72240 cttccacctt taccagttcc accgcctcct gccccgctat cgtcaccgcc tccaccaagg 72300 acagcaccga tagctttgat cgccccagca aggcctgcaa tcttagcgag gatgttgaac 72360 acccggacta gagatgtcgc aaagaatata gcacctatac cccagccgac ccagttccat 72420 gctttggata tttcatcacc cttatctcgg aagattggga tgtactcttc aaggagggcc 72480 tttacaagta tgaaagagtt atataattcg taaggtatct tcatgaaccc gtctatgaat 72540 cctgcgacaa actgacccac ggcggcggcg agtggaccat tagaatccaa gatcttggca 72600 agggtattaa atgtctctgt catcttatca ccgaatccag attcgaagat cttgttctgg 72660 aagttcatcc aagtctgggt aaggcgttgc atagcaaccc ggttaccttg taaagctttc 72720 tgtagtgcgc cacccttgtt agcagcttct gcgtagtatt tagcaacaaa cggaagcact 72780 ttagcagcct tcagctcccc gttcttcatc atatccatca atttggtaac gtcgatggtg 72840 gagtcgttga atgcttcttg cgatgccttt atgaacacct gtaatgatcc tgggatacct 72900 tcagcaagct gttgcttaag ttcttcagcc atgatctggc ctttacccat catctgttga 72960 atagctgtaa taccgcgttg gtattttaca gggtcaacct gaagggcagt tgcatactca 73020 gagaatgact tgaagagctg atcgttttgt gatttagtaa gtacaccgtt tgctgcgata 73080 gacatctggg tataaccctg tgctgcaacc ttaaggtcga gacctaaacg atacgcctgg 73140 cttctcacaa attcaatacg cttaccagcc tcagcagaat catcggagac catcagcatt 73200 gttgcttcca taccctggaa gaactgccca gttttcagaa cgcttgcagc ggcattgaac 73260 gctccgtatg ctgctgtaac actgattaat gtgctgcgta gatttctcag gccatcattc 73320 aaagaaagag tattagcgct ggccttacga agtccggttt ccatagaggc aagttctgcg 73380 cggaaatttg atgccttcat gttcccgctc ttcatgtatc ggttaactaa ggaatcatag 73440 ccgggtaatt tccttgcata tttatcacca tacttggcac gaagacgaac attggcgtta 73500 gagattgtgc taatcttcgc ttcccgtgct cttgctcttc tcccagcttc ccgctctgca 73560 tcgcgggcca ttttctctct ggccttattg tcagccttat cctgttttac ttgttctcgg 73620 cgtattcttg catggtcacg ttccattgcc ttgcgttgct gttcagcaac tttcgggtca 73680 taagccgtag catttgcatt gagaatcgga gatcctccgc cctgagaacc cttatttttc 73740 agacttgctt catatgctgc catacgtgca gcagaaatgg aagggttagt tccataagca 73800 ccgttcttag cagcaagttt ttcttgttga cggagctgtg ccttcagggc attatagttt 73860 gcctgcgact ctggagatcg accagcagtt agtctggaga cagcagcctt acgtcgtgcc 73920 ttttcaatct tatcaatggc ttcacgagca cgagcttctt tctttgccat tgcgatattg 73980 tgagctgtgg tcttagccgc ctctgcacgt tcagtttgat tgagtcgttt attaaccatt 74040 ctcgcctgca tggcggaacg tttcagggca gcagcagggt cggccttagc agaagaaaaa 74 100 gccttcccgg tcttttccca ttcggaacga atttgcttta cagctttcaa ggcgcgtcca 74 160 aaggatgttt tgtcaacatc ccatgtcacc ttgttgactg tggaagtcac tataatattt 74220 gccataattt cctcaataaa aaagccaggc tcctgaaaag gaacctggct tgagattaac 74280 ctcttctgcc tttgcttcgg ggtttagctg cttcggcgtc tgctctcgat ttctcttctt 74340 tctcatggac atcgttgatg aaatcttcga catcgagata ctcattgagc ttgagcaaat 74400 attccatatc ggcagactca agggagatat aagactctcc cttaaagttc ttcagagcac 74460 ggcaccagag atagtcgaac cacgtcaggg aactattttt tcttgcataa tcaatagctc 74520 tttggacgac tttagaaatt ttggacggtg ttactccgct gccacttccg tcggttcctg 74580 atccaccgtc gccacttggt gaaccatccc gaagttgccc agaagtccct gaaggtctgc 74640 gaaaccgtct ttcgtgaaaa aacagccgta gttaatcttc agaacctccg ctaccaattt 74700 gatcaggtcc aacatcttat cctggaagac cgtatcaata tcaatcttgc cagccattcc 74760 gttcacagac acatcttcaa ggatgagttc gaataatttt tcgatatcat cttgctccat 74820 ctgctcaaat aggtatagaa ttgcggtagg tagtgcttca gagaggttag accctccggt 74880 aaacaatgca ccactaatag tagccattgg aactgcgata taacgaccaa tcttcggaag 74940 gtttttcata accttggacg gagaccagtg tgtgattaca aagttcttac cagctagatc 75000 gatttctgtg gtaggtctaa aattcatcat gtgtacgctc ctgcgtcttt taaggttgtt 75060 atatccatgc gtgtttgaaa aggccacatc cttgtggcac acgaaacgct attagacgat 75 120 acctgcaagg ccagccagac cgaagcctgt agcgtacaga gtatctgggc ttaaccatgc 75 180 gtccaggatt ccgatttccc aatccatctg gccaacttca gtaccgtagg tcaggtcagg 75240 ctgtttctga atccaaccaa ctgtgctcag acccatacct tgggagcctt caagaaggac 75300 agggaagaaa atcaggccag tgatggaagc ttgtttctgc cagttagcca agtatccgtt 75360 ccataccgaa gtgttctgta gagagaccgt caggacacca gattggttac gagacagcgc 75420 tgctgacagt tcaccatcaa cccccatgtg ggggatgatg ttatcttcgt tgcgagcaac 75480 gacgatcttg gtatccgctg cgaacccagt gacgcgctga gtcatcatat agagacgcgc 75540 tttctgtggg tcgtaagcat acggggttaa aattctagta tccatttatt acactcctgc 75600 tgttacttgt ccgctggaag aagtagaccc ggttttgtct agcagaacag agatgcggat 75660 cttgacgaaa tgcagggcgc tgttgtagac tagctctacc ttaacgttgt taagagtacg 75 720 agatgccaga tcattagatg gtatgtttgc acgaagcggg attgttacaa ccggatcgta 75780 gaacaccttg ttgacggaat catacccggt aagaatagaa ccgttggtga taccggtatt 75840 cagaggacta ttcatcagga ctgacttcag gttcggcaga tcatcatcgc tcattttcat 75900 ggacaggcca agattagaac ggcgagacat gtaagcgaag atactttctt cacttctgaa 75960 cttcagccag tgaccaaaac ggacaacatc gacatactga ccggaggcac acttaccttc 76020 ccagaatgcg ccgacgccat taatcatacg atagaagttc aggttctggc cccagatagc 76080 tggacgctca gaagaactca gggtcggagc aataacaccc ggcattgtct tcaggtggat 76140 tgagtcacca taggatgggt cattagatgc cattgcaccg atgataccac cttcagggaa 76200 tgcactatca gcaagcgggt catacatacc aatgctagta tcatactgaa gtgctttcag 76260 ttgattagca atagaatctc cgtcgacaac ttttgacagc ggatcggatg ttgaatagac 76320 gtgcagctta tagttagcag cagcataagc agcagctccc agaattgcag aagaaacgtg 76380 ttgttctgtg ctcaggaagt accagttgct gtttgcagtt tcgacctgtg gtagaacacc 76440 gcttacagtc tcagttgagt tgttagtcag tgtgcaatca cctgagtcaa taccgatgct 76500 gaatggctcg ccgataacat cagaagatgt tgccatgatg ccttggtcag attcggttgt 76560 aaccacctca tcatcgttag tagccagcag agagccatca cctttcggag tgattgttac 76620 aacaccagtt gtagctactg caccgacaat tacattaagc gtggtatcgg agttgattgc 76680 agatgccagg gctgttgcaa tactctctgg tgtagatgcg gtagtaacag gaataacgat 76740 gcttttagta tacgcacctg ctgcaacgtt gaaacttacc gggttattag ggtctacgtt 76800 agtctgccct gtgaaatcga taactgttga ttcccatgct tgtcttccga tcataagcgc 76860 ttgggggcgg aaagtcccag caaaggcttt tgtcgcaaaa gtatacgcag gggaacctac 76920 agcgaaacca tcagcagcga gttcatccag atctgtatat gtacgtactc gttctgggaa 76980 aacgttgtga attgcgataa atagaggggt ttcaaaccct acggtgtcga ttggttgtgt 77040 cccgagaaca accgttacgt caacaacctt atcattataa gccattgatt tcctcttctt 77100 ctatttcttt cataaagtta ttgttgatca tctggagccg gatagtaata aaccatctct 77 160 gcattcaccc tctcgatatc ctcgaaagct cctgtatctg tcactccaac gcagacgtta 77220 aaagtgataa gtacagttgc acggttttcg aaggtttgca tgttcaacgg aactctctgg 77280 cgcgataccg ttgaggaaga agaatatgca aatggggaat tggttggaaa atacttgtcg 77340 cagatgtagg ggaggctcaa ggcctgtaga atccgagtta atgcatttga tgcttttcct 77400 cgaaatgctg tcaggttgta aaccacctcg tagttgtgag ttattacagc gttaccgctc 77460 tcatctaccc actcgttcgc agcccagtcc atctggtcag cggtaacttg gttgagcatg 77520 atgaactcac cctctacctt ggatatgacg tctccgtccc cgtcaattat ttttctcccc 77580 gtgacttctt tgcaaaatct ggcgagcgta actgcgaggg cgtcaaaaat atcatcggag 77640 tttgttacga agtctgccat cataggcccc cttctgtccc cgcaggcgta gagatcacat 77700 acgctctgta acggctcacc cctgtcgtct gatacggatc agacttgata acagtaaacc 77760 attccatttc cccacgggaa ttcatgagct ggatttgatc tgctagcagg aaagaacctt 77820 cgacaggacc tttaagaaga gttgacgaat atacagtgaa tgaatcatac tgtctgccgc 77880 cagcctcggt caactgcgaa gtgtagtctc ttgctgcctt gcctgtcaga ggctgaacaa 77940 cgcattccaa gacatcaaac tcttcatact gaatagcgat ctcttggttt tcgaatggat 78000 tgtctgggtc tggctgggaa aaagtacgat gtctcccgat gaaagtcttt ctcggaatca 78060 gcttattcct gcctattagt ctgtagcctg gtgtcattta gtccccttcc cagtggaaat 78 120 cttataggtt gcagatgact tcaggtctcc gtagtggaac atggcctctt taaatccttt 78180 gacatcagcc catgcatcag atacgaggtt attggggaaa agcccgccat cgatgacgta 78240 tcgaatcttg tctgcacctg cttgaccgat ttgtttcagg actggagtcg ggtcttgcgc 78300 tcccgcagcc aattgaccaa agaggtcgat ctgaaatttt ttaagttctt tctggaaaag 78360 aacacccgcg ctggtcatga aagtacgagc cgggaggtta ttccaaccct cttgatgaat 78420 cgctgcaaga gttgcagtat tcaggccaga atagtgagga tcgtcgaaaa agccgtagct 78480 tacctgacga taatcaagct tcttaaccgc attaaagaag ttcataagct ggctaagatc 78540 ttgcgtactt gtgaattttg gtatcatgac tgcatccgtt taggtatttt accacattat 78600 cttagcaaaa tcaacgataa acgtttggat agttagcaag gccaacggcg agggtatcga 78660 cgaggaattc ctggaacacc agtctgtgga attatacctc caacatcgaa aggtccacgg 78720 gagtttctgt cgtatttaac acggttgaac tcgtcttcac gaactccccc aacgataaca 78780 aggcctctga ccgcacttaa gcaatcattg acatagtcag ggttttcaag cagccagtcg 78840 aggaagtctt tccaattctg ataaggagat ccacctttga tctggatagt ttcatcacca 78900 atcttttcaa ggcgatccgt gatcgatgcc tctcctgtgt tcacttcctg aagaatcaac 78960 caacgtacca cgtcaacaag agtattgtaa ataacgtagt aaacagtgca tggcgtgtta 79020 tcatcaccgg ggtaattagc ctttgatttc tctattgcca aaaaggcaag gataatctcg 79080 tcgggtaaga cttccgggga aatggaccca aggagcaggc ggatataagc aacaatttct 79 140 tggtctgtca ttttcgctcc ttcaagctct tctatttatc aatatcttat catagaacgt 79200 cgattttgtc atcaaaaaca cttgacatca tgtgacagga tgctattctc aaagaaaatt 79260 attgaggaga atcccatgaa agcagtaata gcaggtgtta tcacagccat cgttgtctcg 79320 ggtggactta tctactttat gaaaaccaac cccaatatga acaaattcga cgatgtttct 79380 tcaagctggt tggcggctga agaaaaaaca gaggccattc atcggattgc tgggatgaaa 79440 tgcgatacag aattcagaaa ggcattcatt cccggcactc tgacgacgca gacaggtatg 79500 ttagatgaga tggaagaaca agaagatagt ttccaagtaa tgagaaatat ggggatagtg 79560 aacggtactg ttcttgcaac aggaacttac atctgtaaat attataagga tggccgacaa 79620 ccttatcttc aggtatcttt gaaaccagag gcgagaccgc tactaaaaaa ataaggcccc 79680 ggagggcctt tatattacgc cataatgcca gcagccttca gcttggaaag aagggcatta 79740 aagtcggtaa ccagtccagc tacgtcagtc gcaaccgtat tggcctgtgt tgccgccatt 79800 ttaacaccac caaccacaga agtggttgca gctacgggag caaaagtagt aggcttacca 79860 gtaatatcgg cccatgccac agatccgcca ctgccagcgg cagcaataac atcagcgaag 79920 gaaataactc cgccagttgc aatgtcaatc agttttgtac cgtagaccag tccagctaca 79980 ccagatgttg ccattttaaa tctcctaaga ttattacttc agtgcggatt cgaagtcagc 80040 taacatattt tcaaatgtct tgctcttcga cagggtaaca cccttgtttg ctgcgaattc 80 100 agcaagtttg tctttactac cttttttgtc ggcttcatca agcagtgcag atgcttcagc 80 160 aagaagtgcc tttacgtcca cagagtctgt ctcaatgatt tctgtattat cttctacaac 80 220 ctgttcaaca acggtttctt ccgcttttgg tctaaccgta acaggtttaa cttcagacgg 80280 aggtgtaatg tccccgttaa agaacacgat gaagttgccc attctcagag tagaggtctt 80340 ggcgtctaca ggaagaccgg acaggtctgc aagttcctgg aaaaactcca tgaaagaacg 80 400 aaaagccttc atttgcttac caaggacgaa gccatttagg ggtaagcggc ttgaagcgct 80460 aatgttcaat tcgggaatgt atgccccaaa gaacttgaaa agctctacct tgttcgggaa 80520 aatgcgataa ttttgatttg ccatagaatc tcctttggtc ctcataaacc tcttgacata 80580 taagaccacc atgctaatct taaaatgaaa aaagggagag gtgattaaca cctccccctc 80640 ttagaggtag ctttaagcta tattacgcga aagtaccagt cagtttaaca accagctctg 80700 ggcggcagtt aactgtcagg aaggaggttt cagattcaac cttctcttca cgcaggtaag 80760 cagaagattt gtaccacagg tacagttctt gtgccggagt gttcgcttca cgaacatcgt 80820 ctgctggcgc gtagtggatc tggaacatgt tgtcgatacc gcgtggcagc atgtaagctt 80880 caccgtccgg gatgtagccg gagatatctt cgatgtacag aacattcttg tgaacgaagg 80940 aacggttgtt agcgttctct tgtccgtcac caagacgacg gcgcagcggt tcttgagtgg 81000 aactgtagta ttggtatgcg ttcatgatca gcgggtgacc tacgaaagca gagaaccatt 81060 tacgagaagc caggactacg atgtcgtagt tgtttccgtt gtcaccagcg ttgtcgatga 81120 tgaatgcacg accatcgttt tcgagcaggt cagacgggtc aactgcaacg tcagtgaaat 81180 ctacgttaac aacttcctgg gtaacacccc attcggtgaa gtagttatac tgagcggtcg 81240 ggtcctgcgg tgcccaagat ttacccatga ttgcctgaag cattgctttt tctttaagct 81300 gttcatgaga aacacggata cgacgaacaa cgcgttcaac tacatcctgt acagatttag 81360 gagcgtccgc agtgaaatat ttacggaagt tctgtacgtc tgccggagtg atctgacgat 81420 ccagcgggaa gaacgggatg ttgaagtttt tcagttgggc cttttcagta ccaacgtagt 81480 tacgttcacc ctgacgacga cgagctggga agtcggttac aacttcgtca acacgctcaa 81540 tctgggcgat agtagagaca ccgtgataag cctcgaaaag gttcatgttg gtgatcatac 81600 ggtactgacg aggtacaatt tccagagttg cgcctaggtc aacgatctgg aaatcattag 81660 tgcgtactac tgccattatt ttctccttgg tgtagattag atagacgtta ctgggatctc 81720 aacggagccg tcgtaatatt tatcagtgat cttcagacct ttggcctcaa gagcagcgat 81780 agcagcagcg ttgatagcag tagtaccgtc agcaaagaac agtttggatt tgttcagggt 81840 cagaccacga acagcaacca cgaaattgta tttttgacca actacgaaag gacgtggcat 81900 ggtgtaagaa gaagtcacca ggtcgcggtc ggtgattaca ccaaatgcgt ttgcagcgtc 81960 ggcagttgca gccagagtac catcagactt aacgatcata ccggccttca gccctgcgga 82020 ataagtgatt tccatttcca ggaagctgta gccctgatca gaagaatcaa ctttacccag 82080 gacgatgtca gagtagaacc cttgaatcgg attagccatt tatattatct cctcgatatt 82140 aggcagtttt gcgagcgcga gcagcttcta gagctttctg cacgttagct ttaagaacat 82200 cttcggcgga cttagctagg tcttcagtaa caacctcttg gttgatacca ttttcctgag 82260 taccgaactc tttcttcaca gtttcaactt ctgtttccag ttcgctaata cgagcttggg 82320 ctttttccag aagagctacc actggggcgt tagctttttc aatgatgaag tcagcaagag 82380 attcatggtc ttcttcagcg gcaaaagtaa aacctttggc ttttgtaaga gcatttttct 82440 tttctgcttc aacagcagcc ttaataatca gttctgcttg ggcatttttt gcattagctt 82500 cttcaagctt tttaaccagg tccaggtact cctgggattt ggttacatca acagtatcgg 82560 acacagaggt ctccttgttt tcaattgtat tttgaacagg tacgtctggt ttagcagcgt 82620 ccttgatgac ctcagtctcc tgagtgtctt tggcatcaaa aatgacaccg tgctctgcaa 82680 cacccttctc aaacatctgt tggagtttga ttagttcata ttgcttcaca aggtccagct 82740 cttcacctgc atttgcagct ttggcgatag agatggactc catcttcgat tctaaccatt 82800 cttggttatc atcattccaa cgttgcagcc attcatcatc aggattttca gcagcagcgt 82860 tttccagttc tgtttcgaag cccaaaagtt tggcaaggag ttcagcatca ctactccaca 82920 tatcgaagaa gcgacgaagg aattcttcaa agctcatatc gacagtaact tggcgaagtg 82980 ccttaaccac gtctttggta atctgttcag gtgcaaggtc agacttcatc agaagactaa 83040 ccggacgcat atttgcagaa taaccttgac tctcgtggca gagtgcgata cccttatcct 83 100 taatagtttt ggccttgact acgagtgcgc tcattcgttt tcctcggcaa tctcaatccc 83 160 gaaatcgagt ccggtgattt caccagtctc cttgtctgtg tagccagagc attgaatgct 83220 cagtccaccg acagcgttgg cctttttcaa gagccacagt tcaggatcat tgtatttaac 83280 cttagctacc caggtgccag ctttaatgat ttgctcgcta ccgataacca cgacatcaaa 83340 ctcttcttga atccaagtct tctcgatggt aaaggcatca gtctcgacaa tgtggaacag 83400 gttctcttta acaagaccag ccgctcgcgc agcatcgaaa ctttccttac ctttgacgat 83460 tgtctctgga gacatccatt caccgtgggc atccctagtg tttggttcat aaatgacttc 83520 gtaagaaatc atttgttctc cagcatcttt gacaacagat acaggcttgg cattcttttg 83580 aattgctgtc ttcttcagcc ctacatggag tacatcttta gatgctttct caatagcggc 83640 ttcaggagat aggcctgaat caatcaggcc atttgcgaga accagcacct tgctcttctg 83700 aatgagagac agattcgata ctgatgcagg aaggtcagca atacttgagt atttcatcat 83760 tttccccgtt gatagttatt ttaacaccgt ttattttctt ttgcaagtta tttcagtgag 83820 ttgcttagtt atccaagtta gagacagaat tatctcttac tttagacgtc ccattaccag 83880 aagtaccttg cttcattcca tcaccggagc gactggtatc ttccccaagg atcttgagta 83940 gttcctcttg agatgtgttt tcaggaatct cttcatcaaa cccaccaacc tcaaggatct 84000 tgttgataac tgtaggtgtc ttcggcagat aaccaacagc accaattctc tgaacaaatt 84060 tggagaagct ttccatatca acttcctgga tagctccagg cttaagtctt ggcatgtctt 84 120 catcagacaa acggatatta ttaagagcga gtagttgagg aatcaagttc ttgttgaatg 84180 attcacaaat aatatcgata tctcgttgaa caaaatgccc gtggattgtt tgttttgatt 84240 ccgacaggtt gtaagaccct tgaccatcat tccctaagtt gatgaatccc gcaccaaatc 84300 tgtccaagat cgccttctta cgctcttgta ttaggtcctt ggtactgtac tgtttaccaa 84360 ccccatcgat tcccttaagg gtcatcttat actgctcacc gcccttatca ttcatatctg 84420 aaggtaagat gaagtaagat tgttcacctg aatgtgcgtt tgcagcgtca gccatcaggc 84480 cacgaaccat atctgcttca ggtgatctcg ggtccataga tgccttattc agaattgaag 84540 aagggatctt taattcaatg ataccgccga ggtccttaga tgcccctata acttcgaggt 84600 tttcgatcag gattttttca cggaatgcac ggtaacaacc aacaagaggt gatacacctg 84660 tagggtttga ttctgtccca ccaagagaca ttatcatcaa cttattcaca ggaatgaatt 84720 tctcatccgc acttcctgac agatttgtga cgagactcat ggccccagca atctggttca 84780 tcccgttctg gaaattagca aaagctagtg cactttgata aacacctgtg attgtccttc 84840 catcatcgct gaagacaaaa ggttttgtac gagagaggct tgactgagga cggaaagcaa 84900 ttttgtcgat cgtcatatag cctgcgtact tagatggcgc ggattctgtt ctgtagacct 84960 tttcgaatac agagaaacca tactcgttaa atgtcgcagc acttctcgcc acatcgcgaa 85020 gcgtctgttg gttagcaaga ttcttcagag catactcgac gaaatctgcc gcttttttag 85080 actcttcact atctcggttg aaaagaattt taaaatcatt gaaagccttg gtgacaaaaa 85 140 catatttcgt atccagcgct gtggcaacag tatggtcttg cttcatggaa tccactgttg 85200 cgaggaacat aggccagcgg agttcttcaa ccttcataat ctcagattca gcacgaatct 85260 gagacaatgc tccactaccc agttctccag tacggacacg actcacagca aggttttcat 85320 tccctgcttt tgccaccgca ttctttcttt ttctgtttct gcgatttgac acgagtcatc 85380 ccctctatta taatcgtgta tacatagtcg gagcaacaat ccttgggatt acgacaggtc 85440 tgatgatctc cgttttctcc aggaagttaa tacctgaaga gatggcgtca acccagtcgt 85500 ccttacggga cacagtgctt cgctcgccat taaatttctc aagttcattc atgagggctt 85560 catatgtctt tgcgtcaaaa ctgttacgga caatacgaac aaagccttgt tgtgcaagct 85620 gggcaaaggg tgcgaaacga gtaagtttcg acttgttgcc tggcgtaggg tctttctcaa 85680 ccacataacc atccgcgagc aatgctcttg agctggtgag gaattcgctt ataccagctt 85740 ggcctgggtc aactgagaaa ataatcgtta catcatcgcc atcatgttct gcttgttttt 85800 tgataattgc atcacgttcg ccagccttct tacagaagcg gccctgagtt cctgtggaat 85860 agagaccatc atcaacgaac tcggcacaat aatcaccgga taaatagtaa aaaccctcgg 85920 tgtctttact cactttcacg gaggctgtaa agtcaggatg tctgttacca gatgtccttt 85980 cagttcctgc cttatcgtat ggccttacag atgtgcaacc taaaggtaga catgccacct 86040 ctttcaaata ggatctttga aaatagtttg caccctcagg gcgagcattc cagttaccat 86 100 aaagtaactg tgccttttca acttcaggaa gccctttcag gaatgccaga tattctttgt 86 160 tattctccag catcggaggg ttatcataaa tgttagcgga gatgaaggaa aatgtcagag 86220 catcgtcggc gtcatcacca taaagctctc tcagttcttc ttgagactcc ccccagacaa 86280 agttaccatc ttgacggagg aaccaacgga tgacaccgtc acgctcaggg attggatatc 86340 catcatcgtc aagataccaa tcgataagtt cttttatttt gtgatccggg tccgggttac 86400 aagaaattac catgcggctt gggtatttag attcagaacg tagacgagag attaggtagt 86460 cgatctgctc ccattcgaac tggcatcctt catcgaaacc aacaaaagtg tactgaagac 86520 cctggtggtt aagtttgtcc ttcacatatt ccatgtgaga ccattttacc tttgcgccag 86580 gacgaccctt tttgaatgtc tgtgtctccg cgtcaaagta tgggaatatt gcctcaagct 86640 ctttctctct aaagcgtggt ttccatgcat caggtagctc attataaatg ctttgtgctg 86700 tatcaaataa accaccctgg cctttcaact gaggtgtggt tctacggaac atgatacagt 86760 tcgattttgg atcatcgata tatgctaaag gcattaattg taacagatac gatttacctg 86820 accccgcagc gcccccaatg atcaggattt gcgccttatt ttccaggatc attttctgct 86880 tagggctggc gggtccaaaa gtcttactca aaggacctcc attattatat gctataggag 86940 gattttacca cgaaagatca taaaaataaa gcccttatca cgaaataagg gccttgtcaa 87000 tcacttttga ggtgtaaata tgttacgaat gtatgcctga aggataagta acttgctacg 87060 tgtatcagct gcttcaagat tatttttctt aacaatagca ctgtttttag cgttatcagc 87 120 accataagga agtggtgttg ggtcagtagg tgggatcata gcgtgagcag ggggcttaga 87180 aagcacctca gagggattaa acttatcaac cactggaact accttctgtg gagactcgca 87 240 tccaacaagc atgattacag agaggaatat ggcaagcaaa ctctttctca tttaaccccc 87 300 aagctttcat tatagatatc aacaaagtcg ttatccagcc caaacttttt accagcttca 87360 gatttgttat atgcctgttg tttttcatcg agtctggatc taagtaaatc attcttagcc 87420 ttctcttctg caagctggcg actaagttca tcagagaagt cttgctgcac atttttgaaa 87480 tcttgatttg catctttgtt gtttctcatt tgcagaaccc atttgttatc cgtatcatta 87540 accccacggc tataggcctg ctgtatttgg tcatcatacc accacttgac ttcaaaagcg 87600 ccccacagga gcgccagaga aaggacagca acgataacca gtttggtgtg tccctttata 87660 aaggtccaaa ccacactgat aaaatttatc atgagatatc cccatcacaa tctaataatt 87720 caacaatagt caccttattc cgaggagcct tatcttctcg gtttacagac actcgcccat 87780 ctccttcgta ctcaaggata agcggatctt ccacgataac cttaaacaga caagcaccag 87840 gttctatctc ccctacgtgc caactcccct gaaccccatt cttgcataag agcttgtacc 87900 tctcttgtgc agcatcaaga tcaaaataaa tcctgatctt atctagcatc tctggattgt 87960 cgatgttatt gctattaagg ccgaatacgt gtttttcggt atgcgcctgc atcatgtaaa 88020 aatgcacagc actagataca gcccagaatt ccttgaaata caggcgatcg gtgtttttac 88080 gcaggcgttg gaaaacattg aagatatctt tagcttcgag attaaaacgc cgttggcctt 88140 tacgcttgtc ggtgatagtg gcaatcgtgc tgatagcaat atcacctgca ttatccagtt 88200 tatcaaataa tccctcaaat gaaaacggct cttttgtatc gaagagttct tcaacgtttg 88260 tcccatacat accgctaaga tgctttttgg catcttccca gctttccatt ttgagacttg 88320 cgacggcaac acccaacttc attgtttctc gacgggagat tgtataccca cgggcctcgt 88380 actttgacgc tcggagcata ctgatgatcg ggtagtctgt cgctggatta agaaccaaca 88440 ctttctgtgc agcatgttta aggaaacgac tgtcaaacac ccatgtttca tcactaaatg 88500 agaaggcacc catgttgatg gtgtagtcaa acttatcaaa gatctgacca gcgttgtcaa 88560 ataccgagaa tgcaatgcat tgcatcaccg gattagaacc atctgaaaac ataatgcttt 88620 tatctgtcat gccaatatta cgaacatatg agactttctt ctttctactt tcgagcagtt 88680 tttcaatacc atcccaagtt gattcagaga tatcagacag atcaaaaggg cagtcactgg 88740 caaacttatc ttccatctcc aagatctctt gcttagacac tttctgagaa agaaccttga 88800 atcttggcgc acgggattcc catacctctt tcccattgtc taaaatgaag aaatcacgat 88860 aaacacgttt ctcttcattg tatcccatcg ttttaggtga caggtcatgt tcaccttttc 88920 gtaggtctat atccatcatg taagtaatga agatctccaa gtcatcccat gaacggaagt 88980 acaggtcgag atcattaact tcccggttgg taaagagagc cgtgatagcg ccacctgcga 89040 ttataacatc gaggctacga aggatatggt aaatatcctc agagaaaaaa ctttttagta 89 100 aacggtattc tcgaagatgc tcattcttct cgtaagtgtg gatcattctg gtctccttta 89160 gtaagttact tttagagtgt accagaaaaa gaaaagcccc gcaagagcgg ggcgaggcaa 89220 aggagaggag atataagaat ttattgttat tagaataaga aaagtggcga agggatttta 89280 ctcgtcgagg gtgtctaacc gtttccacag ccgaaacctt ccttagtgtc cactttgaat 89340 tttagatgcg tggatgggag tcgaacccac aattttcggc ttatgaggcc aacgtgatct 89400 atatatccgt ttcactaaca cgcaattgtt tggcgggacg gggtggattc gaaccaccga 89460 caccatgatc ttcaatcaag tgctctacca aactgagcta ccgacccaat atgtggtggg 89520 caaggagaga ctcgaactct cacgccatag gacgccagaa cctaaatctg gtgcgtctac 89580 caattccgcc acttgccctt atcgatcctt cgggagaatg ccaccctcgg acagttacca 89640 tgatgagcat ttataggcaa tatactcatc aatccttgct ccgttctgat aatcgttacc 89700 gtccgaggac gcattgcgaa cctatcaaca gccgaagact ttgccgtatc gttgtacacc 89760 gagtcaggct tccgctatat tggtgcaagc acagggattc aaaccccgac ctttcgcctt 89820 cgtatgacga agctctattc agttaagcta tgctcgtatt atttaccatg tctccggtat 89880 ttttcacggc gacgtgcttg ttgttcttct ttcgtaagag aatcccaagc aagtttcttt 89940 ctgaccctat ccttttcctt gaactcttct ttggtaaaga atttctgatg gggttttctt 90000 gcagcagaga tattgcacct gagatgactg tatgagatat tattaatatc aaagaacaac 90060 cccttaggat ctgcactgtc gagccagggg ggttttatgt tctatggaaa aaattatctc 90120 gctccatagg agcgccacag tgatggcagt aattggagtc agtctttaca ataaagtccc 90 180 ataagagatc ttttaccaat ctaccactcg ctgtgcttgc attcattcct aactgcaacg 90240 ctttcttgtc tttcatcgac tatccttaga tgtctaatta tagaattggt cagtgcggta 90300 ggatttgaac ccacgaccca gagcatccaa ggctcccacg ctaccagact gcgctacgca 90360 ctgaaggtgt agattttaat tatcccaggt ctctacaaaa ctagtatcgc tggctagcta 90420 atatcatgcc ccgttagggt acaattggtt tgatacgtcg aactcatttt gagtgccttc 90480 cggcaattta catcaacata tcaaatatac gaggttagag agaatcgaac tctcggctcc 90540 agcgtgacag gccggtattt tgcccaacta aactataacc ccataatttg gcggaaaggg 90600 ggagtttcga aatcccgacc cctcgcttaa caggcgagcg ctctgcctct gagctaccaa 90660 tccatttaaa tactttatca gtcaaaacaa ccttttgcaa gggatatttc aacccatttc 90720 aatttggcgg gatctgaggg tttgcacctc acctacggtc ctggatgccc gtcattctgc 90780 tccgctggtt gccgtcgcat ttccagcctc attaaactat cgtcccgttg tttggtgggc 90840 cgcgaaggat tcgaaccttc aatccccgag ttaaaagccc ggtgccttat ccagtttagc 90900 tagcaaccca taactgtcct gactgtaatg ttgtcggctt ctcggcagac agtaagcacc 90960 caagagcgca taggcaacaa tacagcttct aattggagga gagcaacaga atcgaactgt 91020 caccgtatcg ctacggtggg accgggttca aaccggagtc tgcaccttgc agcctgctct 91080 ccaagattat tgtctacttg gattttcacc aagacagggt taggcccgta gcgtgtagcg 91140 gcattcctcc cagaaccgtt ccccaactct catggggatg atagatacct acgcgaccct 91200 gatgtattga acatctttag acaatttgga ggaagatgtc agactcgaac tgacacgccc 91260 atttctgggg tactgtctct ttagcaaaga gatcccttac ctgattaggg ttaatcttcc 91320 aattgttctt taatttcttt acgaagatct gctttttctt tcgcacgagt aatagggact 91380 gattgaattt cttctgcaac accacagtta ctaccgtgga gcctacagcg tccaaacact 91440 ttcttgcaac gcaaaagttt ctgcataaat cctccataaa gtggcggtgg aagtaggatt 91500 cgaacctacg gacccctttt gggggcctac acctttccaa ggtgctgtct taaacctctc 91560 gaccattcca ccaaattcgc ggcagatatc gtacaaacga aaatctcgac tagaacacat 91620 gacgtgggaa gatagagata atcacgtatc tgcaaattgg ggtgacctgt gggtatcgct 91680 cccacttcct caacgtcaca ggttgaacat catctgataa atgcttaggc cacgcatgag 91740 tattctcaaa agaaaacact caaacttggc agggagatca ggacttgaac ctgaactacg 91800 gatttcaaag acccgtgtac taaccaatta caccatctcc ctacaatcgg tgagggcgcc 91860 tgaaaccgag ccaggctaag tatcggactg caatcctaag cttattttgt tgccgccatg 91920 cttacttatg accgacaaga tttcccgttg cagcggtaga tcatagtcat tttcaacatc 91980 cggtcgcccc cattatctgg catgaaggtg aggagtcgaa ccccttacga ctggctttgg 92040 agaccagctt gctcccggag caattaagtt acccgcacat tgtttggtgg gcatcagtcc 92 100 gattcgaacg aacctcagca agtatgccag tgagctacaa ggtgcgcacc cacttcaccg 92160 ggcgttttcc aattcgcctt agatacccat tatttggtac tcccaccgag gatcgaactc 92220 ggatttccag attgaaagtc tgacggcctg tccatttagc cgataggagc attttttggt 92280 gtggtactct aaacaattct tctgacgata cagatgcctc ttgtttattt cccacattat 92340 ttggagcgtc tagagggaat cgaaccctac tctgcgaggc ttggaaggcc tgcgacacac 92400 ctcgtgctta gacgccttaa attggtggga gtatctggga tcgaaccaga gacctctcga 92460 ttatcggtcg agcgttctac cgctgaacta tactcccatt aattggtggc ccaccctgga 92520 ctcgaaccag gaaccccgaa gggcacggat ttacaatccg ctgcaataac cattctgcca 92580 acgagccaat taaccttgtt tgaactgaac aatatctgtt gtgaatggtt tactcatagg 92640 agtagatttc ttatcatcaa cattagttgt ttcagcttct tcattctctt catcgaagta 92700 atcagaaagc atttgttcac ctttctcaat tacaaatcga gcaatatttt ccctgatatt 92760 gtcctttgtt gtggcacttg tcataagatc tttcaatacc ttatgagcat caggaatcat 92820 agcaatcata ttggtcttaa ggtcaaggat attcttctca agctgaatag cattagactc 92880 ttctttaagg ggtctacctt ttcctctacg acgctttgta agttgttgtt ttactgccat 92940 aataacccca cttattaatg ttatcagatt taaatttatc tgtcaagggc cattttatca 93000 ttttttataa aaatattcaa caacttggag cacggtaggt gaatcgaaca cctgacattc 93060 ggtttgcagc cgaagctgtt gccactccag caaccgtgct tttgggggac ccgattattt 93120 caattcgctc ccacacattc gggtcaagac gtgtcctata gtctttcgac gcttccacag 93180 ctcggagtaa accgtcccgg ctgtcctgtg aatttggcga aggcggcagg attcgaacct 93240 gaagccttag aaatggtgtt ccctcgtgga atcgaaccac gaacaggagc ttagaaggct 93300 cttattatat ccatttaact aagggaacta aaaataccac tatgtatttt tctatgacag 93360 tttgaacaaa caaccacaca tttgcgtatc tcagctttga gtgtctctgt tgaattagaa 93420 tagcctctcg atatattaaa ctctttatcg ctgtctggat gatgaaagtc taaacatgca 93480 tagcatttct cactgcaata agcacacccc tttaaggttt tgtatcttct gaccaacttt 93540 ctgttatgcg aagctatttc tgcatttctc ttccttatag ccccttttct tatggggctg 93600 gatttatagt gggaagagtc tataattctt ttgcattccc tacaacaatt ctgtaggccg 93660 tctctcttag agctattctt accgaacagt tcaagtggtt tacttttcct acagtgagaa 93720 cagactttca tactcactcc aattactcga ttaacgacgg gttagaagcc cgttgagata 93780 cgccctctta aactgatgcg ccctcccgga ctcgaaccgg gaaccctggg agcttaacac 93840 ccatgcctct gccagattgg accaaggacg caaaacattt atgtgctgcg actctctcaa 93900 aacacttgtc gggagaaggt caagaaatat ccgcgaaata cccctatcgc cccaccctat 93960 gcaatgtctg tcgtttcggt ttgcaaccct tgcgacttct attccaaatg gagaaagccc 94020 agccataaat gttttgtgga gcagggtggt ggaatctaac cacctatgta ttctccaccg 94080 cacgtatgta gcggggatat tttcaggtct ggatggacct cgcggttgac aaaccgccta 94140 ccctgcattg gcttctcgaa caggaatcga acctgtaccg tccctatcgt gggaccgctc 94200 taaccaaagt aagctatcga gaaattgttt ggtgctcgca gtaggacttg aacccacgac 94260 cttctcctta caagggagtt gctctaccaa ctgagctata cgagcaagaa atgctgtttc 94320 cgattaacag cctggaggag tcagttagcc atatcttgtg agctaagatc ctatatccag 94380 gatttaagta atcaaagaaa ttttagcttt atggtttaga agtttcaagt ttaaacatta 94440 agctttgaac gataatcttt gaatgttgaa tgttgaagtc tttcgaattc gcgattcgac 94500 aatttcgatc aaaccgcatc attgtgcgga ctgacggaaa catacgttta agtatcatcc 94560 tgtacgatta tgttcggagc agtttaacct ccggccccgg tagaggcaag atgtttctga 94620 cttcgctaac caaaaacagc atttaaaaac tttaccagct atccgcagga attacaagat 94680 gttaatcaag aatccctgca aatattttag attgatcctt caatctctac ttcagtccgt 94740 gcatttgact cggaaagaac aaagtcaacg ttagacttaa agtcttcaat ctctgcttcc 94800 agagaacgaa tgcgatctgc cagaccaagt gggtcaacaa tggaaggagt tcccatgcta 94860 cgaactggcg cttctactac agccaactgt gcagcgtctg gcgctttatc acgttggaca 94920 tatggagcac gagcagcttc aagcttcgcc tcgaattcct gtgtatcacg gttcaggcga 94980 acctgagcat gattatactg agacttcagt ttgccaagca gaagctcttt gaaaacgatg 95040 gtgcgtttac gttcaatcgc ctgagctacg gtcatagact cgccagcgat ctcaactttt 95 100 gttacagcgt ttgactgaac aactttcgcc ttcaggtcgt cgcgaacagc cagaagatcc 95 160 tgaacaccct ggaagtctgc ctgagcagat ttctcgaagt cctcaacgct ctggatagag 95220 cctgggatct gacggtttgc gtcagtgcct ttcgcgatgt gaatcgtgtt cagcgcttcg 95280 atacgcttct gaatcttttc ctcaaccttg gtcagggtag ccagagcgcg ggttacagac 95340 atcttagtag acatagaatt ctcctctcat gaaatttaaa atttgagtta cttcaaatat 95400 ttgccgacat ccgtgtcggc actacgcatt agtttttgcc agtgttgaca acaacgccct 95460 ggcggttagc atcagctttt gcgatttcca gacgggtttc gcgttcagcc ttcagatcac 95520 cacgcgctgc ttcaagctgt tctgtcagca ttgcaatacg gtcatcctta gccttgctat 95580 tcgcagtaag ttctgcaatt gcaaccttgt gagcagattc cagatttgcc ttaaccgcat 95640 tcagttcgat tgcagcgcta cgtttaacgt cggcaactgc gctttctaca gcttcagcat 95700 tgttctgctg agagatcgcc agctctgcac gaaggtcttc aacaacaccc ggttctacag 95760 ctacaaggcc gcgagctttc aggatagaat tcagaacgga atcttcgttt tccagaactt 95820 tgatcttcag cttggatttt tcttctgcca gtttttcgtt gaactgaact tcaatttgtc 95880 ccagttcctg ctgcttaaac tgaatttcct gactgatctt ttcagaccct tctgccagag 95940 attgcagttc agcgactact ttagtcagac cagtagcggc agtggttact gctttagtgg 96000 cacgttcagt tacggaaatt acagttttag aatcagtcat taagttctcc tttgcgttaa 96060 attaggttta aatactacac ttacagattg tgtttgtcaa gcgaatcttt gattatttct 96120 tcggtggtag ggttgttttc aaaccatgac caataatacc aaagaacaag caggaaagag 96180 atcactgaca tgatgataaa gataacaccg ccactcatcg tacaacgtcc ttaatgcagt 96240 caaaaacttc accaacgacg tctgcggtag gtgatacgat aatctcatca gcggcgtcaa 96300 taacttctgc ggctacatct acaaaaggtt ctgcaacagt tgccgtgaca acaacagcag 96360 taccaacaat atcgccagcc atacgtaaca gggatccgaa catttcgttc tccttttggt 96420 ttagatttga aacgagagca ctttcgtcca tttaagctat cgccctgtgc cactacgcga 96480 gccgggccag caagaacggg agtcgaaccc gtatctctct catttcaaac ttggtggggc 96540 atgaaggatt cgaaacttcg acctggctta agaggccgcc acaccaacca ctgtgttaat 96600 accccgaaaa catgcccgtg tttttaaaga cgtttcacgg aaacgtcatt cccaatgccg 96660 gaggaattac tttttcttct tacccttcgg agctacggtt tcaataacct tagtttcctt 96720 taccttacca gcacgttcac gcttggtctt gcctgtgcgg atgcggtaag aagcagagat 96780 aatctgacca ccttcaatcc gggtttcgga tttatactcg cctttacggc gatcgaaaac 96840 tgatacggtt ttctctacac cgccgagacg cacatcgtgc ggcgcagaat gagtctgagt 96900 agacttcgac tcaaactgga aaggctgttt gatagcatcg atggcggata ctttcttagc 96960 agtatttttc ttagtcataa ttttctcctt tgcattttat ttgggaattt gtcccgttta 97020 tgttcatgag gatactaact caatcagata tcctcgtcaa catttttaat tggtggcccc 97080 cggaggattc gaacctgcct acctctcgat tatgagtcga ttgctcatac ctaatgagct 97 140 tgagggcctt atcgttcaga gtggaattga accactgacc ttgtccgtat gaagaacctg 97200 ctctaccaac tgagctactg aacgcttgat gtggtagata ttatagatca cctgtttcat 97260 tgtcaacgtc ttttttacta ttactgcaaa taaaacagaa aatttctctt ttaggaccta 97320 tgtactcctt cccgcagtta gtacaggctg aatgataata cataccccgc agactttcac 97380 caggccagtc tctttcagag aatgcgatgc agtgattaga ggtcaggtcg ttcatcagtg 97440 tatacctctg ggaacaattg tcttgcccta gccttcattt caacaatgat gtcattcagt 97500 ctaagactga ggctatgcat tctttctaaa gtttccatat aatgcctctc agaagtctgg 97560 gtgctcgtca gaagaaatcc cctctccgaa accaataaag ccgtcaaatt catctttcat 97620 cgttttgctc cttttcgttt tgaacgaatg atcgccgctt cagcacgacg ttgttttcga 97680 ttcttaaatt gttcggaaga ttcggagagc gtatttgatt gtgagatctt catcattggg 97740 gtagagatag tataatccac cttcttcacc gaaggaggca acgtatttcc aggcttcaat 97800 tccaaaacca gttgtagaaa aagcgatctc atccgcttca tcagtggctt catccagttc 97860 cctatgattc gattcgtgtt caatatactc tccgttatca gttttgtaaa cgagttttag 97920 tttaaacata gtgtcctacc gtgtaagttg ttaagagtca agttattttg ataactcaat 97980 cttaccagcg gacacctttt ttgtcaatcc atgatacctg agtcgttgac accacgacgg 98040 tattctgcta tggaaagtgc tctgatacgt tctatgaact catcatcggt ctcccattca 98 100 cagtcatcat cgtaatattc atcaagacct tcctcaacct caggaaccca agacttcttt 98160 tggtcttcat gaacagatgc cctgttaaaa tcatgtttcg cgactaaatt acgcaccctc 98220 tacctcttcg agatcgattt taccggtatt ggtatttatc cagaccgtct tatctttgct 98280 cgcattcatc tggtgaccac aaccgtaagc gatgatgcag acacccggcc cgtgggctac 98340 aaggtctgct tcgacttctt ttttgcaaac tttgcacgta tccattattg gtccgaacat 98400 ttttctttct cctcttgttg ttgacgttgt ttttcgataa tgacatccat agcggtgtat 98460 ggtttgtttg taccgtgcca ttcaagcggt tttaaagttt ccatagtacc ctcagtaagg 98520 tgggatgtta gaccaatggt cttcatcatc aacacaatcg ctcggagctc caagacagaa 98580 ttctgccaga ctaccgaggt ggtcgttagg gaaaccaaag gaataaacat ctctgcgaat 98640 ggcttcgtct aaatcaaaat ttccgtatgc aggattaaac ttagtgaccc ggatgtcggg 98700 ttctgatttt ggttttattg aaatcgtttt gtgtacatca cgagaagaac tgttcgggca 98760 ataataaaaa tcaccgaact ttccagtacg tattcccatt ttcgttttgc actttgggca 98820 tttcataagc aaacctcaag aagaacccgg ctaaatgccg ggtttgttgt tttacaattg 98880 ggaagctgct cgctcacgga tcgttgtcag gtcttcatcg acaatcagtt tgccgttgta 98940 gaacacacga cgcagttcgt tatcgtcaga ctgtacatct tcaagctgac aattgtcaac 99000 cagtttcagt tcgccattct catcacgaac aaccttcagg aaaccttttg cagatttctt 99060 accgaggtca gtcttaggct ctttgacaac catgatctgc tgaccatcaa tcacagcgcc 99120 agttgctttc acagccatac ccagtgaatc acgggttgtg tactgggtgg taaaggaacc 99180 aacaccgtac acgatattac tggatgcaaa gcctttttct ttcaggcgtt caaagatgtc 99240 ttttgcacga gcaacagtga tggagtcacc gtagatcagc ccaacgtggg tgtccagaac 99300 cttgtagcct ttggagttaa cttcaccacc aaaaatttcc cacaggcaag aaatagcacc 99360 aatggcttcg tggcgaggga gttcatctcc gatactccaa atatcatcct gttcattacg 99420 atcaataaaa taatattttc cattcatctt cacaacttcg gcctctgatg gagaaggatt 99480 ctcatcataa aggcaagtgt aaatggaatc ttcagcttgt tctccagaaa actcaccata 99540 aatacgatat ccggcaatga tgtgctcagg aacacctgag tcaggacgga atacaacacg 99600 accgtcacgt gccatgattt cctgtttcag gatcgctgct gctttggtga taatagccca 99660 gaaatcatag ctgtctgcca cgtaggaaac aaaaccttta gggaaaattt ccgtgatgta 99720 gaaacgcagg aattcaacct cagccaggaa acgtgcttca tccagagtta gttccgggtg 99780 ttcaccttgt aggcgaccga cgataaagcc gatgttcgtg gttgcaacag agtgttcaga 99840 tgcaggaata gaaccagcaa cgaacttgcc tttcatgttg taataacgac gagcatacag 99900 aatcgctggg atagtgtctg tacccattga gttgatcagt tgaccgaact cgctctgtgc 99960 agcatcgtga gtaccagctt caccgcgata ggcgaagcag tggttctgga atgcaacatg 100020 gtcgttgtta tcacaggtct cagcagccca tttttcagac agcttgcgat actgccagaa 100080 cgtcgttgca gttgtgatag ttttccaggt ttctgcggag atcacacttt ccaggaagtt 100 140 aggcaaccag taaaaatccg ggtgcgtatt ctggattgta aacattggga cctgaaccgg 100 200 agaaagcgtt ccttctggaa gagcacggat ttccagagga agataaccga gatcatgaag 100 260 agcctcaaag ccccaggttt ctaccatgcc aatgccgatg ctggagtcgc aaacctcacg 100 320 ataatcagca accgcttctt ctttcgggag gttgaagaag ttattgttga acatgtcgat 100380 aaggaaccac ttaataaatc cctgaagtcc agcaaacatg acacgctggt cgttatcggc 100440 gaagtggatg aagtgcttcg cattacgagg ggtcatgtta tcctgaacaa tttcagaacg 100 500 tttatcatac atggagatgt gtgaaggttt gtaaaagtca gcgaacagga taggactttc 100560 ttgattaagc atgttttgtt tctcctttgt ttgtttaata gggcgattgt acgcccactt 100620 attcatttgt caattaaaag ttttcggtcc agtcgtggta cgcgtagatt tcatcaacgc 100680 cgccttcgta gataacttct ttaccgaagg aaaagatacc gtgagttacg taaagaataa 100740 cacgttttgc tccttttgcc ttcaatgctt gtgccagggc gatgaatgtg cgaccaccat 100800 cgcagatatc atcgacaata acacactcac gtccttcaac atcaccgaaa acagcagtcc 100860 cggtaatttc atttgtcttc aggtcgcgca cttttccagc ttccaccaga ggaaggcgaa 100920 gtcgatcgga aactttctga gcttttttac gtgctccggc gtcaggggca acgataacaa 100980 catcttttcc ggcaagacct tcatggaatt ccgcaataag agcgtcctga ccacggattt 101040 taacgttgtt aagcaacgcg gcggagacat cgctgtgcgg atcatcgaca atgaccttgt 101 100 caaacccaag agagttgacg atatttgcga aaactttgat ggataacgct tcaccaggtt 101 160 gcattacgcg gtcctgtcgt gcatatggga tgtacggtag atgcaaagtg aactgtgcag 101 220 tatgatgaag gccttcaagg cgagaacatg catccaccaa catggcaaga gccataacat 101280 cagtagagtt tttgattttc gcagtgatgt ctacgaaacc aataccacct tttggggtat 101340 gcgccatgtc aattttaacc tgttcttcac cacctttgaa cgtaaagtga tcgacaggta 101400 ctacaagttt gttcagacga agttctaaac tcatttcata tatcctctat taacaattat 101460 gtaatgtcta ggttttgcat tcccatttga atcctgaaaa ccagaacgta tccttctaat 101520 gtatccaaga gactccatct ttgtcaagaa ctctgatact ttcggttgtg acttctcgct 101580 caacccaaac agatggcaca aagatttctg agatgggtaa aaaacttcat cgccaccatc 101640 tgggtttaga ctcttgaagt aatcatacct ccaccaaagc ttgattaatc tttgcaaatc 101700 ttggggtgag agacggtcat caaaaagcca ctgtgtcgga atggtgacat atgccccatc 101760 tctgatattc acagtgttgt caccaatctt tatctccacc accatctcct gtttattcca 101820 cgataggtat aattagaggc tacaccacta acccaatact gtcaactcta attattccag 101880 attaggaata tctaattatt cccgaacagg aatacaatac taacttatca tttaaactaa 101940 cttatgatct ttaaaaaaca ataaaacata agatctaaaa caagatcttt tactacagag 102000 tataaatact ctatatccta gagtcggtga ctcgatgagt tggattatcg tatgaagaaa 102060 agatgatgtc aagtgttgac atgaactttt taacgtgtag aatctagtta atgttaaagg 102 120 agattgctat gttttcaagt aaagaaacaa aaattatcgg tgaaatggtc tgtggtaagc 102 180 cacgacggaa accggagcag accgatgaag agaagaccaa gttgatgatg ttacgtgaag 102 240 tgtatcatga atgtggtgaa gaccacaatg tgtgcgtggt attaccagat ggtataccag 102 300 ttgacaaggt cttcgataac ttttatgctt cgataaagtc gagactagct cgacgtaatg 102360 tgtgtgtaac atatgcaaag gacttgactg tggaacacat cgagaacaac aatgttgtgg 102420 tggatctaag tgaaatccat gtaacgctct agaacgtgtt ctaaggcgtt ttaatggtgt 102480 ggtagtacac ttgggttacc aacccatatt aaattaaata cagggcctcc cagaggctct 102 540 gagaggtatt gtggaggatt attttggata tgaagagcat tacccgtgat gactccatct 102 600 ataaaggtgc ttatctagct ctgagagaca tcatgaagtc tatggagaaa aagtatggtg 102660 tgaaactgta cttagatagc cgggtagact ggggaaagac atggatggat gcttcagttt 102 720 acattcatgg tgataggcat atcgttaact tggtgtgcat gaaacttatt gtgtggcaac 102780 attaccagaa aatcagggat gggattctgt tcgcctaccc ggctgaggat atgaaatgaa 102840 gaaagatatc aggaaacctg tcaaggaaaa gtttgatacc tctgcatttg tgttcacaac 102900 cgatgtgggt gtgattaaag atgctctaca gcgactgaat gaacaggagg cagatcctga 102960 agcggaacca ctgacaaagg atcagatcta ttggatgggt tggtgggagc ttaacatgcc 103020 ggaggttgat cgtcgcggat taacacgggt attgacatgt gctcaggaaa atgctgcact 103080 gggtctgtat aagaaaacta cgaagaggaa gaaaaaatga gcagacttgc aaaactaaac 103 140 agaagaaaga aaatgttgaa agaaaagcag aaaaacatca cggctacttt ccaagtatgc 103 200 cgagaggcta tgaaggcaaa tcggataaca ccttcgcaga gacagttgat ccgtgatatt 103 260 cttcgtcctg tgctccacga ccttgaaggt gaagttcgtg atgttacact tcatattcaa 103320 gaggaacttg taaaaagata tcaggagaat acatgattga ccatgttacg tcagacactc 103380 actggtggca taccaacatc cttggtttcc catcgtgtga taaattccgt aagaatctgt 103440 acggtcaaaa agaagaccgt gaaagtctgt atgccatgaa tgcaggtatg attgaaatct 103500 ggaataagca cgtcaaacca gatgatgtcg tagcacacct tggtgacttc gtgatcgctt 103560 acggtcgcta cgttgagcca cgcactcgtg atattctgga aaagatcaac ggaaagatca 103620 ttcttgttgg tggtaaccat gacaaccgag atacgaaacg tatcttccgt gaattaggtc 103680 atgaagttgt tgattataaa gagattaact tcagcactgg aaaagagaag gtgcatgtgt 103740 gtatgtctca ctatccgttc gcatcgtgga acaaagcaca ccacgggtca gtcatgttgc 103800 acgggcatag ccacggctcc tatacagccc ccggtggacg tattctcgat gtaggttggg 103860 atgttcatgg tcgtcctctg acgatgcgtg aggccgtcct gatgtgcctc aaaaaaccaa 103920 tctacactgc tgaccacgga gaataagatg cataacaaag aacgaaattt catagcacgt 103980 aacacggcga agtctttctt cgctactatt cacattgccg gggattatgc tcaggccgag 104040 aatttgtgtc gccagtgggt tatgcaaggt gcttgtgtgc agattgctcc atgcacctat 104 100 gtttacacag gtggtgtcga agatggtatg actgtgcggt tgatgcagta tccacgtttc 104 160 cagcgtcagg agcatgagat attatcaatg gctgtcgaac ttggaaaata tcttgctcag 104 220 gagatgtgcc agataagctt cagtatcgaa accccttata atacaacata ttatcaggcg 104 280 gaaggttatg aaaaaagatc ttgatcttat ccataacgtg gcctttttga ttagcgagct 104340 tgaagaatat gttgacgaac tagatctgag catctatgat gactacagcg aaatgaaatc 104400 agcacaaaaa gaagtgctca aactattgaa aaatctcaga cgaaggagag aacatgaaat 104460 tctgcgtaga cgacatggtt gctaaaaacc tagtatccaa aaagacttac accgacggcc 104520 cgttcgcggg tctgtctgtt ctgaagtata agaacaatgt gttctgggat aacctgtggc 104580 atactgaccc acgtcttctt gaatgccgtg gcatggttgt tgatgcagag gacaacgttg 104640 ttatctggcc tttcactaag attttcaacc gcttcgagaa tggaactgac ttacccctcg 104700 atcagcaggt tgtgtgtatc cgtaaagtaa acggttttat ggcgacagca gctattcata 104760 aaggtaagct tcttgtttca acaacaggga cgcttgactc tgagttctct gatctggcgc 104820 gaaaatatct tgaaaagatg aaattagatc ttgttgcatt tccagaggac tatactttca 104880 tctttgaaat ttgtgacagt agcgaccctc acattgttga ggagaaagaa ggtgcatact 104940 tgatcggtat gcgcgactta gctttaaatg ggaaaatgct tgaagaatat cgtcttgatc 105000 gcatagctga agtgatcggt gcaaaacgtc ctcaatggga tgttgttcca tttggtgatg 105060 ttgttcataa tgttaagcat gtgggacatg agggctacgt tatccgtaat gtcggaacag 105 120 atgacgaaaa cagcgaactg cttctgaaaa tcaagtcccc acactacctg gcgaagaagt 105 180 tcctgatgcg tggcagccag aataagtggg acatgatctg ggataaccca gaagaggcca 105 240 agaagcgtgt tgacgaagag tattatggcc ttattgactg gctgcgctgg gcttgggaaa 105 300 aagaggagtg ggcgatgcag gactctcagc atcgtcgcaa gattattgaa aaatactttg 105 360 aggataaaaa gtgaaaatat ggcttgatga ccttcgtgac ccaaaagact atggtcatcc 105420 tgatgcttta tggttgaaga actctgaaga tttcatggag ttccttgaag atcgtagtaa 105480 gccatatcgt cgtgtcactg agtggcattt cgataatgat cttggtgaga tctcagacca 105 540 cgatgggtat tggtgcttcc ttaatcttga ggagaagatt gtctttggta agatgttgtt 105 600 tggtcctgta aaactcttcg tgcatacatc taacccatcg gcaggacaca aatttatgct 105660 tgcaaaagag agcatggcca ggtatggtgt gacgattcta agaaacaatt actgaggagg 105 720 caaagtgaaa acactttata ttgtccgtgg agtttcaggc gcaggtaagt caacactagc 105780 acaaactttg tcttctgacg ggtactggcc tgtttgcgaa gctgaccagt atcattacac 105840 tgaagacggt gtttatgact ggaagccaga gaacatgaat aaggcccaca aatggtgcca 105900 agacatggtt cgtgatgcta tggaaatcaa tcttgaaaag atcatcgttt ccaacacaag 105960 cacttctgaa aaagagttgc agccatatct tgtaatggct acgttatatg gttatcaagt 106020 ggtcagtatt gtacttgaaa atcggcatgg taatgactct gtgcataatg tcccacagga 106080 aatccgtgac gcccaagagt ctcgtttacg caactcgttg aaattacaat aaggagaaat 106 140 agttgagacg cttaatagtt attagtggtg ctggtttttc tgctgagagt ggtgtccgta 106 200 cattccgcac cgatacggac tctgggaagg ccttgtggga tgaatacgat cttgaagagg 106 260 tatgtaatat ccacgctttc cgtggtaact tctaccataa aacgcacatg ttttataaca 106 320 agcgtcgtgc agagttaccc actgcacacc cgaatgcggc gcatcttcgc gtggctgagt 106380 ggtacaaacg ttatcctgga caagttatca acatgacgac taacgtcgat gatttgttgg 106440 aacgtgcggg tgtccctaaa gaagatactc tgtacataca tggttatctg aaagagatcc 106500 ttgttaaaga tgctttcacc aagaagataa aggttgtcga tattggctac gaccaaattg 106560 atcctgatga ttatgattgg tgtaaaccaa acgtaatttt ctttggtgaa aatgctccgg 106620 cgtatggacc tatgtctgat accctggagt ctttaggaag ccaagatctt gtaattgttg 106680 ttgggtgctc aaacacggta atcaacttca actgggagtt gttccctgcg gttatgcggg 106740 ggaccaaagt tgttgttgtt aatcctgcta ttaggtatga tgaacaaatg atgtatgaga 106800 atgcgggtgt tcttgtatat cgtaccggag ctgttgatgc ctttaataat cccggcctta 106860 tcaagatagt tgagaatcac cttgaaggta agacaccatt gcaaagcaag gagaaataat 106920 gcaacaagta aacagtacac tgtacgccct taataaagat ggttctttcc agtgttggaa 106980 ggtgtttatt gctggtaatc aggtagttgt agagtttggc aaggttggtg gtaagaagca 107040 acaaaaggtt accacctgtg aaccgaagaa cgttggacgt tctaacgaaa ccaccgcaga 107 100 acagcaggca ttggctgagg cggtttccaa atgggagaaa caggttcgcc ttggatatcg 107 160 tgacgataca agcaagcttg agcaggaaga gaacttctcc ccaatgctgg cccatgatgc 107 220 aactaaacgt tcaaaatcaa tagtttatcc tgcatacgtg cagccaaagc tcgatggtgt 107280 acgtgctctg gttactcttg atgcagatgg cttcccacaa ttcaatagcc gtggtaacaa 107340 actgtatcct gtaccgcttg attctgagtt gtctgaacag gttaaatccc tttctgagca 107 400 ttcagggttt gacaaattcg atggggagct gtacattcat ggtctgagtc tgcaaaagat 107460 tgtcgctctt gctaagaagt ggcgtacacc agagcagatc gaggaagaga ttgaaaagga 107520 ttatcagtct gacctgaagc gccatcagaa agctattgac aatggggaag acagttggaa 107580 agatttcgat ggtgatgttt actctgtcgc gatcgaacca gttaaagatg ttgatcgtta 107640 tggcggctat tcaagccttg acctagagta ccatatcttt gacattccgt gttcaaataa 107700 accctggatg attaacgatg ggatttcaga ctatacagat aaggagtgtc gatacaaaga 107760 ccttatggac actgaccact tcacctctgt tattaaagca gataaaataa atgtggtcca 107820 agggaatgtc tttgacactg aggatgaggt taagcaatca atcggacatt ttatgcagca 107880 aggctttgag ggtgctatca tccgaaattt caaaggtgtc tatgaatttg gtcagcgatc 107940 ttctgatctc cagaaatgga aacttttcca agacggcgag gctaaagtcc ttgattctgt 108000 ggaagataag aacggtgagg gtgtattact ctgcgaagag gaagatggta cacgtttcaa 108060 ctgtaaaatg aagggaaccc acgcagagag atctcaggaa cgaatgctcc ttctggtggg 108 120 taagtttatt aacttcacgt tccaagctag aactgatgat ggtgttcctc agttccctgt 108180 cggccaaagc gttcgtgaac tcgatacatt aacatgggag cctgtatact aatgggattt 108240 tatcgtaaaa aacctgtaga ggttgaagca cataagtttg acgggtcgtc aaccagcgca 108 300 gggcagatcc ataattggat ggaaactggt gtgtggaagg attccgaaat ccacactcgt 108360 gattgtggtc gtactgtaga gataaaaacc ccagaggggg tggtcgtagc ctctgctggg 108420 gattatgtaa ttaaaggggt ggctggagaa ttctatcctt gcaaatcaga aattttccat 108480 gcaacatatg acccgctgga agacactgat cgggaacctg ggaactaccc agctaaagca 108540 atccgtaagg gtgatgagat catgttttgc ggaaaggttt ataccgtaac gaatactggt 108600 gcgatggggg aggatgttat cctgactctc ggcgatggtt cccaaatccc tgtgcgccct 108660 gatactcaaa ttatcgtaac aaaggcacag taaaatgatc tggtattggc tagcgctact 108720 aggcgcatca tttgtaacag gaggcggcat ttatgccgct tacagattcc gaaaagataa 108780 gctggatgat ttctttgact gggttgctgg aaaggttaaa cgtctgctga tcatctgggt 108840 atttgttatg ggccttgtta cgctggccct tactgtgcca ttatggcata ctatgacttg 108900 tcagttcgac ggctgggccg cgaatacaga gaccagttat tcatggtaca aatcaacctg 108960 cctgtataaa agcaagacag gggcatggct acctttaggt atcagtcgtg atcaaccgca 109020 aggagatggt gatgcatcaa attaaagaaa atactgtaga ttttgaagcg catatctacg 109080 attctgcgat gaacgacaac tacagatggt caattcgtcc agatcctgat ctgccaggtt 109140 cagttaacct ttcttacaat gagttagctc attatgacaa ccgaggctat gagcagcggg 109 200 gtatggtagg tttcgataaa gaaacttggg aaaaaattaa atacgccatc gatggtgttt 109 260 ttgaaaaaac aatttaggag acttaatgaa agaagcttat gatactctga atgctatgct 109320 gcgcccaacc tctcttgtta agtatgcgaa acatgttgta gattggaatt ctatcgcagc 109380 ctctgcaaag ggtgaattta ccccattgga aaagcagtgg gagtttgtag gagaggagtt 109440 acaagaaacc gttacagcat taatcgaaaa tgaccgtaag gaagttgttg atggggcgtg 109 500 tgacttgttt gttgtggcgt cgtatgctta ttggttgagt aataactatt cgctatcctt 109560 aacctataat cctgatctta agttttctcc tggtaaagct tttgatgctt ttgcgaataa 109620 agattatgaa gaaatgctca aactgagtac ggctcttctg tttagtcttg atattcaatt 109680 ggataagaac atgagtagcg ttctggagtc taacgattct aaatacccga ctgtgaccga 109740 ggtcatgtct ttgcataaag gtcttgaatt ggcagattca cttgaggcag aatgtgcttg 109800 tattgaggag cgtaacaatg gtcgttatga aggtgttcac ttcagtattg ttaaaggtgt 109860 tttgggccaa gaagaccgcg tggtattctt cgacaaaggc ggtaaaatca tgaagccagg 109920 gactttcaaa aaaccaaaca ttattgtttg acaatcgtat cggggtctgt ataatgaccc 109980 catcaagaca aaaggagaaa gaagtggaag aaaatattga ttattctgaa attgttgcct 110040 tggctaaacg ccttaaaatg accatcatga atcgcggggc atcttcccgt catgttatcc 110 100 gcttcacgat gaagcgtcgt tggggcggcg taaagaaata cgcttatgaa tgcacactcg 110 160 gcacactggt atctcatgtc aaccagatcg agagaatggg cggaaaaatt gtcggcattg 110 220 acaattgaag cttgacaaat aaaactgaac ggttatactg accacactaa accaaacaaa 110 280 ggagcaatat atgccacgta tgccaaaaat caaaatcgaa ctgatcacct ctcttccgtc 110340 tgacccggtt cagcgtaaac gcctaaaaga tagcgtaact gaagtggttg atctccagcg 110 400 tcaaatcgct gatctgaaag accagatcaa agatattcgc tctgtggaga aagaaacgca 110 460 taatatctct ccaaaattct tcaatagcct ggtgaagcgc gagtatgatg ttcgcttcga 110520 agccgaaaag aaaactgctg cattagaggc cgaaaaagaa gtcttcaccg aggcagacat 110580 tctgtttggt cgtggaaccc caaatgttgc acagactgaa gccgatgatg gtgctgagga 110640 cactgaataa tgaaatacta ccttaatggt gttggcctat ttgtcttcat ctgcgtcgta 110 700 ttcgggtttg gtgttccaac tctggtttct gccaaagata caatcagtgt tattggcggg 110 760 tttgccttag tcttcactgc cccggttgtc gtgtggtact ggttgcgtaa ggtcttcatt 110820 ccgaagacaa gcgctgaagg agatcgataa tgttgctaaa tctgaaggcg gcaacttggg 110880 aaaagttgca gcacttggca aagtccaaag gtaagtctgc ggcatcttat gttgcaaaaa 110940 tcgtagatga ccacgttgat gaaaacgtaa agactgagta taaaatcaaa gaggagaaac 111000 aaactaatgc ttaagaatat caaacgcgta gtatttgctg gcctgatcgc cctgggtgca 111060 attggtctga ctggttgtga acgtgcaact gttccggcgg gttatgtggg tgttaaggtt 111 120 gacctgtatg gtgatgagaa aggcgttcag cagcaagaag tgggcgttgg taagtattgg 111 180 ttaacctgga acgaagagat ctatcagttc ccgacgttca accagttgaa caactacgaa 111 240 caaccgttta acttccagac caaagattct atgacggtta ctgcgaagat cggtgttgag 111 300 tattacgttg accgctctaa ggttaccaag atcttccaga cctaccgtaa aggcgtccag 111 360 gagattaccg atgtcaacat ccgtcagaat atctctgatg cattgatcaa ggaagctggt 111420 acgatggata ttggtacgct ggctggtgat ggtaaatctc agcttctgga ccgagtgacc 111480 aagactctta agcagaaact tgacccggta ggtatcgtta ttgtgaaact gtcttacact 111540 gatgaccttg gttatcctcc tcaggtaact gcgtccatca acgctaagat cgaagcgact 111600 cagaaagcgc tgctgcgtga aaacgaaatc cagcagacta aagctgaagc tcagaaacaa 111660 attgaagcag ctcgcggtga agcagaatcc cagcgactgc aagctcaggg ccaggcagat 111 720 gctaaagtag ctctggcaaa aggtgaagca gaatccatcc aactgcgtgg tgatgctctc 111780 cgtaagaacc ctgaaatcat gcaactggaa gcgatcaaca agtgggacgg taaaaccccg 111840 accattatgg gtggcaacgg tgcagtacct ttcgtaaatc tgccagcagg taagtaaagg 111900 ttgacaaaag gcccggtgat tagtatcatc gggtctcaac ttaataaagg agtctcatga 111960 tgagtgttcg cagctatctt tttggagttc tcacaggtgt ggttgtgatg tgtctcttat 112020 taatctcttc cccagtattt gccacagtca acacactttc tttggtggat gaatacaccg 112080 atggaagctc taaagtatgc atctacagcg acggtaatcg cacagaatct gttctgaaag 112 140 aaggtgctgg ttcttgtcca agtaagaaaa catttcattg aggcaatgat gcgagtaact 112 200 gataaatacg tcttcttctt cacataccga gatatgttca gtaatcacta ccgccaggtt 112 260 attcctattc gttgtggtgg ttacgagttt ttcactgtag aacattacat gatgttccag 112 320 aaggcaatgc tcttcgatga caaagaaatt gcttcccgca tcgctacggt tgataacccg 112380 aatgaggcca aagctcttgg tcgtcaggta aaatgtttcg acaacagcgt ctgggaagag 112440 aatagaatgg atattgtgac ttcaggcctt gtattgaaaa tgaaggccaa caggtctgtt 112500 ctagaagcgg cgcttgggca tcgagatgca gggcgtaagt ttgtggaagc ctctccttat 112560 gatgccatct ggggtgttaa attaaacgaa tatgatacac gtatcgatga tcctgccaat 112620 tggcgtggtt tgaatcttct cggtgagtgc tgggaacggg ctattgatat tgttgttgct 112680 gcaacgtgga ggtgacttga aattagagat cgaactggtt ccaaagacag cgtggtttac 112740 taatcttcga tctcatctca ccaaagccca gtgggatgtt gtcagaaaga aatgttatgc 112800 aaaagccaat tattgttgtg aaatttgtgg tggtaaaggg actaaacacc ctgttgagtg 112860 tcacgagatt tggtcatatg ccgacagtac cattacctta accggtctga ttgcgctatg 112920 cccctcttgt catgaagtca agcatattgg tttggcaggg atccgtggtc gtggtgaaat 112980 tgccattcgt cactttatga gagtgaatga agtaagccgc gctgtggcag agaaatatgt 113040 taaggaagcg tttgatttgt atcatgaacg aagcaagcgt gaaaagtggg aattggatgt 113 100 ccggtatttg gacgagtatt tgagtaaaga ttgagagggc tagtggcata tccgtatgat 113 160 aaagattgga aaaacaaagt aacgaaagac tgcgtattag ctttggatct tgaccagaca 113220 tgctttgtgt cagccgccgg tgctgaaaag cgtacaattg aggtcactca tattgagtct 113280 ggaagaacaa agattttccg taacaggact gaattttggg gatcgacaaa gaaagttgtc 113340 ggtggatgga tcaaagacca aaacatgaac atggaggcga aggcaagggc cgaaggccga 113400 gtgtttgtac cgtggggtag ggatgacttc acgattaaag acattcagga accggaacct 113460 gtagaaaact gccttcatat cttgaagaca aagatcaatg ctatctttga acaccttgag 113520 atggaaagca atacaggaat gggtgtactt ggtggtgagg gtaacttccg ccttatgctc 113580 ccagctccag agcgttacaa gggtaatcgt gaggatacat tacgcccact ccttcttcag 113640 gaaacaaggg attatgttac ccggaagtat aacgctaagg tgatcaatgg tgttgaagca 113700 gatgactatc tttctgttct tgcttatatg gggtgggaga attaccagaa gaccgggaag 113760 ttcaactaca tcgtggcatc gtttgataaa gaccagaaag gaaaccctgg gcttatcttc 113820 gatactatgc gcgattcaga agagaagaca tggaagcacc cgatccctat gttgatcgac 113880 gattcgatgg gtgagatctg gatggaaggt aacaaggtca agggatgggg acgtaagttc 113940 ttcggttacc agatgctttg cggtgacagc tcagataaca tcaagccata ccagtgtttt 114000 gatatcgctg gacgtttcgg tgatacggcg gcattcaacc tgatcggaca ccttcaggat 114060 gagaaatcca tgtggcaagc gatcattaac caatataaaa cctggttccc gaacggtgtt 114 120 gagtttactt cgtgggacgg cacacaacgg aaaatgagtg caggtcagtg ggcatctatc 114180 atcttccaga tggtctacat gaagcgttct gcgaatgata agacaaccct ttcaagtgag 114 240 ttacgccgtg tggggatcgt atgattgata acttaataat gcaggcagtc atgagggatg 114300 ctgaggcgct ggctgttccc agcgtcaagg gtaaattctt agtcgccaca gggttgtggc 114360 gcatggtcga atctggtgat gattgctatg tgattttcac tgatgactat actgatccta 114420 atgttgcatt caccgtattg cttctggatg attgtgagct ggtagaaggt gagaagctgt 114480 tgatgttaac aagcgtcttg ttggatactc aagaattctc acttgttgtc ttcaaggacc 114540 aaaatgactc ggaggtaact gatgaagctg atgtcggttg accagagtct tagtcattgt 114600 gcggtggtta tttgggatga taaggccgaa aagcccgaag caagatacat gatccgtaca 114660 gggtctactt cgagtaaggg caaacggaaa aaggatgtcg tgtatttcga tcatgtgatt 114720 cagcagatcg attacattgt cagtaagatt tgtgagtacg taaggcttca caaaatcgac 114780 acttacgtca tggagtcgtt ggctcttagg tctgtgggta acgccacccg tgacctcgct 114840 ggactgttct actgcattca gatggcactc ttggagcact atatgagcgt agagcaactg 114900 catgatgtcc cccctacctc tgtgaaggct tgtgccagaa accttttacc cgaggcagag 114960 cgtaaatttg ttaaagaaag agttgacaaa aagaccgggg aaaaggtata ctccaactgt 115020 aagattaaga tggaaaaggc acacatggtt agggctgtag attgtgatat gcccggctgg 115080 ttggatggtc ttacactcgc ggctggcaaa gcagattatg ctgatgccta cctgataggg 115 140 aaggcgtttc tggagggatt atcgcaaagc gagtaaaatc taaatcatcg aagcccagag 115 200 taaggaagaa gccagtagtt gtgccattaa caccggaact ttgggtgaaa gatgcaaagc 115 260 agattgctgc tttcagaaat aaattgattc tggagcagca agggttagat cctatactcg 115 320 gcgagccact tcgcaagccg tgcttggatc atgaccattt cgaaggtaaa tgcagaggtg 115380 tccttagtca gtgcgtgaat acttttgagg gatatgtcct gaaggcttgg atgaagtacg 115440 tttcagagaa tactcagacg tcgttatcca ccgctcttag aaatttggca gattacttag 115500 agcaagactt cagtggctat ccgcttcacg gcgggtttaa gaacgatatg ttgaagtttt 115560 tgagaagatg caccaacgag aagataattg aaagagctaa ggcggacctt ggcataatta 115620 tccccgaagg tactcagaaa caagacagcc tcttgctata ccttacagag ttcgtcaagc 115680 agacggagga aaaacatgcc aaagaaacca cttaaattct tttacagaaa ttggcgaggt 115740 aagtgcggat atcgtactgt agaagaaccc gtcatgtggt atgggtctac ccagtatcac 115800 aagaactctc aatggtttat tagaggttat gatctcgata aacaagactt tagagatttc 115860 gctgtgaatg atatcattga attcgtccga gaggtgtaat gctacctgta gataaaaaga 115920 ttatagaact tcatgaaagc ggaatgagta accgtgaaat tgctcgcaca ttccttggaa 115980 aagagtcgag agagtcatac atccgtttgg ttcttaagcg tcatagcgca gggtctacgc 116040 ctttaacaaa ggccttagta tcggactata agaaagccaa gatcctgttc ttagatatcg 116 100 agactgcacc gctgaagggg catctctgga gtctatggca gaatggaatt gggcttaacc 116 160 agatggtttc tgactggtac atgctatctt tcgtagccaa atgggctgac caggacgagg 116220 tcatttatcg cgatatccgt gataattacg ataaggaaag tgatgcatct atccttcaag 116280 acctgtggga cttgcttgat gaagcggatt ttgttgttgg gcataatgtc cgtaagttcg 116340 acattaagaa ggtcaatgct cgtttcctat tgaatggaat ggataagcca tcaaccttcc 116400 gtattatcga taccatgctt atcgccaaag ccctgtttgg attcacctcc aacaagctgg 116460 aatatctgac cgatcgcctg tgtacgaaat acaagaagtc taagcacact aagttcccag 116520 gacacctgct gtgggatgag tgcttgaaag gtaaccccga ggcttgggat gaaatggaag 116580 agtataacaa gttcgacgtt ttatcgaacc aagagttgta cgaaatcttc atgccttggg 116640 attctcgtct gcctaacttc gatctgtatg ttgatggtgt tctggatatg agcgagtgga 116700 tcgaggatgg cttccattac accaaccttg gcaagtaccg acgttaccgt cacaagatca 116760 ccgggcaaca gcgtcgtggg agaacaaacc ttctctcgaa agagaaacga gcgcaactgc 116820 tatcaaatat tttggtttaa ctttaagggc ttcggccctt tgcaaaggag attctatggg 116880 aagagaaatt gttgttaaag ttcctgatgc cgcagatgat gagtggctgc gagagcagat 116940 cgaatcctta cgtgtaagga tcgaggctgt tgtagaggtt gaggataacg aagaaagctt 117000 taataagtta ggggcttgcc ttgacatcat tgatgcactt caacagtata cggggtacta 117060 atggatatta ttgttctgaa tgctccccca cagagcggta aagatgagat ttctgcgtac 117 120 ctttgtaaag gtaacccaaa catcagccac gaagaggtaa aggaactcct ttttgaggtt 117 180 gctattcgtt cagcgggaat ttcccgtgag ttgtgggatg caatgtatac ccgtcggtat 117 240 aaagagatcc caagcccata cctgatgatt gatggtgtga atgtgtcgcc acgtcagtgg 117 300 atgatccatt gctccgaaaa ggtaatcaag ccattgttcg gcaagtcagc attcggtaaa 117360 gctgctgtgg aaaagttgaa gcagacctat gcaaatgacg aggtgattgt attctcagat 117420 ggtggctttg ctgaggaaat caaagagttg tccgattatg catactcgac tggtggtgaa 117480 ttcttccttg cacgtatcca ccgaaaaggt tatgattggg ggaatgacag tcgtaactgg 117540 ttataccttg acggcatccg aggtcatgaa cgtgacttcg ataacaaaga gggcggtatg 117600 aacgactgtg cagaagagat ccttgagtgg gcaagaacaa ttagctatgg agaagacgat 117660 gcgtaaaccg atgaatatag gtattgatgt cgacctaact tttgtggatt ctggtactcc 117720 ttggcttcat tggttggaac tgatgtatgg cgttaaggcc gactgtagtt tgccaccccc 117780 taacccacag gggaagactt actataatct ttctaaatat tttccacccg cgaaggttaa 117840 tcaattacct ccctatgagt tctgggaaga tccttatttg tacgataggc tgaaaccacg 117900 ccctggcgct gttgaagcag tggccgcatt tgctgaagct ggtcacttca accaatttgt 117960 atcacactgc aaaaagggtc acttttcgtc taaggtacgc ttcttgaaac gtgagacaga 118020 agagttcttc agccttgagc cgggttctgg tcatggtttt tatgcgacga agaacaaagc 118080 aggtcttaag cttgacgtca ttattgatga tcgcaatgaa ttcctgaatc agttcggaga 118140 tgacgtactt aagattaagt tctggactcc gtatgaccaa tctgaggagt tgaaagtctc 118200 gattgacctt gagacatccg actggagtca tattcaggac tttattctgg acctctcctg 118260 atgaaaagga atagatgcga gggaggtgat ttcatcgtcc gtcagggtaa gtggtacgaa 118320 gtattcgatg agaaggataa tttcgtgtac tcattcaaag cgacaagcga catgtgtaag 118380 aatgtgctta accgctactt ggtgttcaag gcagaccttg atccaaatgt taactacaaa 118440 attaagaggg ttggaaaatg acaaaggatg aaatggcgga acacatccgt acacaagcaa 118500 cggctcgtgt gaatcgtgtt attgaaggta tgttcccagg tacaggactg actgcggata 118560 tcatgggtat tgatgcggat tttaataaag gtctttttga tgacgtctat ctgaacttat 118620 tctctctccg cgagctggaa gagattatta ccccccagat caaatacaaa gaccgtcttg 118680 ctgaacttga cctgttagtt gaaactgccg tcgccgcccg tatggctgaa aaccaagaca 118740 agattattga gaaattagga gcaatgagtg agtaatttga tttccgtaaa aattgtagct 118800 gacagcattt ctccttcagg cattcgaatc ataaccttcg aacttgaata cccacgaata 118860 atccatagtg agctgatgac tcaccgactg ttaagtcgaa atgcgatgag cagtcgtgct 118920 attccgatta agaaaatgat cgagcaggtt cagcaaaatc ctgcaatgcc tgtgaagttt 118980 ggtaagaacc aacctggaat gcaggatgcc ggggagcact cagcacagct tggtgatggg 119040 tactcggcag aagagtggtg gaaactcgca ggacttagtg cagcccggtt tgcagcagaa 119 100 tttgcagatg cgggttatca caagcagatt gcaaaccgcc ttctggaacc ataccaaaga 119 160 atgaagacag ttgtcaccgc tacagactgg aataacttct tctggttgcg tgttgacccg 119220 gatgctgatc ctacgatcta tgaactagct aaggcaatga aagaggctag cgataattct 119280 atcccagacc ctcttgaacc gggacagtgg catacaccat acgttgacca cgtttatggc 119340 tttcaagata tcgacgacaa agagtgtgca gtatttgaag gctattgtgt tcttgacgaa 119400 gagaacaagc ctgtaatgtt gactctggaa gaggctttgt ctgtttccgc atcttgttgt 119460 gcccaggtat cttatcgtgt tctgaatacg agcaaagaaa aggccttgga tatctacgag 119520 aagttgatca gtggtaacaa ggttcatgcc tcaccattcg aacatcaggc cacacccatg 119580 acagaataca gggaaattga gaactctgat tatttaacta tcgggcatat taactttccc 119640 cgtgatccaa gctcttggga agaaggtatc acacacgcag atcgtcaagg gcaactttgg 119700 tccggtaacc tgcgtggttg gcgacaacat cgccagttag tgcctgacaa tgcaatttca 119760 ggttgacaaa gatatcgtta attcgtatct tagaagcata ttaattaggg gcgattttgc 119820 cccttgtcag gcagaatgga gattacatga gtaaagagaa acgcaagcca ccacaacata 119880 tttcggtcac cattgacttc ctgagaacgg tcccaggatt tgatgttcag aaagataatg 119940 acctccgcgc tgccttatac gcactcggtt ttcaggttac cgataaagat gggaatccta 120000 aacacgtaac tgtgttccaa aacaaaaatg taagatgtgc caatatgcca tcgacgtatc 120060 gtaagacaat gatttttgtc ggagaaatgc gacctgatta taaatacgcg aagatataca 120 120 acggtgttga aatccttgat gtgggggttt attcaggcag tgatatggaa tttgttttag 120180 atcttcctta cgacatccct gtaactgaaa aagttaacac ccgcaagtat accaagcgag 120 240 gggatcgacc agagacattt gaaatcactt tcgatattga agacgaagct cgtctgggcg 120 300 atgtatttgg cctggaggac gaatgagtaa agaaaaaacg aaatggaaag accgtggctt 120 360 cgatgataag catcattatg ccgggtggct ctactttaac gatttaaccg atgacagtaa 120420 aatgtacgac gatgtttact atgatgagtt ttctggtaaa atagttaaca tcgttgcgcc 120480 agatcaaaac gagaaagacg atcaggttgt tgacgaggca gatgagtttt tgtctcaatt 120540 tgaagaagaa taaggggaaa gtttgatcaa tacagttgtg aagagtgatg gcagtgtggt 120 600 tccatttgaa ccagaacgtc taaacaaggc cgctatcttt ggtgatgacg gtaatggtaa 120660 ctggtcgtat atctcaatgg atgcatataa gcgactgtat gacggctgca ccactcgtga 120 720 agttaaccag gcattgatcg acgcctgtgt gagtcgtaaa gacgaagccc attcacggat 120780 ggctgggcgc gtcctgattg gacaaatcta caaggaagct tttggcggat ttaagaaaat 120840 cccaagcctt accgagtttt accaggacat ggtgatgcgt gggtactggg aagaaatggg 120900 ctatactgga cctgagctgt taaactttga tcaagtcatt gaccacagta aggacctgag 120960 ttatgggtat gcggttctga aacagttccg ggataagtat ggtatcaaag ataacatcaa 121020 tgatatcctg ttcgaatccc cacagatgat gttcatgggt attgctatgg ctgttatgaa 121080 gaatatgcca ttatcccgta ggaagaatga cgtcatcaga ctgtatacgt atctctctga 121 140 tcttaaaatc aatgcaccaa cgccgtacct gaatgggttg cgtactggta aaactggata 121200 tgcatcctgt tgcattatca aagcagacga tacagctaaa agtattggtg ttgcccgtga 121260 agtggcgtac actatgacgg tagcacaggc agggatcggt tattacctgt cctcccgctc 121320 tatcggcgat ggtgttcgtg acaatacgat caaacacatg ggtaaactcc cgtattaccg 121380 tggaattgat gttggtgtta aggaaaatcg tcaacaatcc cgtggtggtt ctgcaacggt 121440 gtctttcctt gcgttagacc cgcaagttga agaactgatg cgcctgcgta atccgatgac 121500 ggttacctca aagcgtatca acacgatgga ctattcaatt ggtgtcaatc actcgttcat 121560 gaatcgcgta gctaagaatc tggactggat gttggtgtca tataaggatg ctcctcagtt 121620 acatgagggt atgttccgaa tgacaatgca ggagtttgat gctgaggttg cccgtgtagc 121680 agcagatact aagattccaa agacttgggt gaaggctcgt gatctggcaa tggaactgat 121740 cactcaacgt gctgaaactg gtcgtcttta tgtttactgg cctgacgaaa tgaaccgtca 121800 tacgccattc cttgagacaa tttactcatc taacttgtgt caagaaatct gtctgccaac 121860 aaaagggtat acagatatgc gcaatatttt caacccgacc atcgatgatg gtgaagttgc 121920 attgtgcttt atcgcctctc tggttgctgg tcgtgtttcc gaagaagaat acgaggatgt 121980 tgcttactac accgtcctga tgatcgacaa cgttatggat atcatggatt atccgtatga 122040 gaacatgaag tacacagccg aatctcgtcg ttcgattggt gttggcctga ccaaccttgc 122 100 acactacatc gcgaaacaca aagtcgcgta tggttctcct gagagcaagc agttggttca 122160 cgatctggca gaactgcata gcttcagtct gcataaggca agtctgcgac tggctaaaga 122 220 gcgtggtgtt gctccgtgga tgaataagac taagtatccg cagggttggt tgcctatcga 122 280 tacctataat aaggcggttg atagtgtcgt gaagaatccg agcctgaagc aggactggga 122340 aactttgcgc caggaaatca tcgaaaatgg tggtatccgt aacagtgtct tggaagctta 122 400 tatgccgaac gaaagttcat cattagctac caacacaaca aatggcctgt atccggtacg 122 460 tgaccatgtg atcttcaaga aatctcctca aggctctgtg ctgtttatcg tgcccgagta 122 520 tgaagagctg aaggaatatt acacgtcggc ttgggatatc gatacgaatg atttgattga 122580 tatctatgca atcattcaga agttcgcagg ccaggcaatt agtgcggatc tttacatcga 122640 ctatacccag ttgccggatg gtaagatttc catgaaacaa caacttgggt atctgattcg 122 700 cgccacgaag atgggtatga agacatggta ttacctaaac tccaaagttg gggctggaga 122760 ctccctcact gaggaacttc atgctaaagc aaaagctgag gaagagacaa gagctgttgc 122820 accacttatc gccggggata ctgaagatcc ttattgcgaa agttgttctt tataagttgt 122880 aggggcttcg gccccgtttt tgaggagaga aaatggcagt ttttaacgta gaaaacaccg 122940 cacataagac cggggactac ccactgttcc ttggtcaaca gatggggatg tatgactcca 123000 tcaataaaaa gtatccgcaa ctgtttgacc tgtataaaaa gcagaaagaa caggactggt 123060 cagaagatga agttgaactg agccagtcta tcactgactt tgctacttgc agcaaatcga 123 120 cttacgacgt catggtgcag accctgatgt ggcaatggga agctgatagt gttgcagcac 123 180 agtctatcat ctgtctgttt gcaccgttta tcacgaatag tgaactgttc gccatgatga 123 240 tgaagcaatc agagattgaa gtcctacatg ctctgacgta ttctgatatt gttcgtcaat 123 300 gtctgcctaa ttctcgccag atcattgaag atattcagaa caaccaggcc gtccttgaac 123360 gctctggcgt cattgtcaaa ttcatgcgtg aattagagat cctcggtgct cgataccgta 123420 ttgacccgga ctctgttgac aaagaggaaa tccgtcgagg aatcctgaga gcgatgttct 123480 ccctgttggg gctggaaggt attgaattca tctctagctt tgcctgtacg ttcgctcttg 123540 cagaacaggg tgtgtttgtc caggtggggc agctagtaca gaaaattatg ttggatgaga 123600 tgctgcatac caagatggat ttcggagtta tcgatatcct tctgaaagac ccggtatgga 123660 aggccagttt tatcgcaatc aaacacgagc tgaaagcaat cctggatgaa gttcgtacca 123720 atgaatatgg ttggggcgat tatctcttca gtgaaggccg tgcgatcatc gggttgaacg 123780 ctccattgct gaaagattgg actgactgga actgtgctcc gatctacgat tactacggca 123840 ttgaaaaaga tttcgtagca ccaaaacgtg atcctctccc gttcatggat gtttggatga 123900 acccttccaa gcaacagaat gcgaatcagg aacaaacaaa cactgattat cgtcttaatg 123960 cgacagtcaa tgacgctgaa gatgaagtct gggattttta aggagtaata atggatagcg 124020 ccaattttga atctgtagta tacgatccgt ccaagctggt agttactttt ggaggcgagc 124080 gtgtggtagg cttctcaagt gatatgaaaa tttccatttc ccgtcgattg cacggagtag 124140 ctaaggctaa aatctattta caggctacca gcccttgggt attaaagctt aaacaggcgc 124200 taggccatcc tgcaagggtt gaggcagcgt atcccgtttt tggcagtata tcagaatcca 124260 tgcgtttcgt tggggacttg gtagttaaag ggtatgatgt tgactacaca tcagaaatcc 124320 cagtattcac attccttctt gaatcggaga aacaatgaat ctgaagaatt caaccttcac 124380 catttatggt aaggataact gctcacactg cgtccgtgcg aaggagtttg ccattgcaaa 124440 tgggatcgag tatatctatc tgacactcgg aaagaattac accaaggaag agctggtaga 124500 gcaatgcgcc ccggttatcc ctcgcaccgt cccgcagatt ttccgtgaga cggactcctc 124560 aacggagtac attggtggcg cggatgactt cattgctttt gtgcaaaaac atatgaaatc 124620 ctgttgacat agcaaccttc tgtctgtatg atttatgtaa tcctgccgag aaatctgtcc 124680 ggcaggaaat ttagaggaga attcgaatga gtaagaaagc actgcgtaag gcatatacca 124740 aggaactggc tctggaactg cgtggcaaaa agccgaagaa taaacgctct tctgatgaag 124800 aacttcagca acttgcagca gacgctgccg ctcgcggggg ttactaatgt caaaaaaggc 124860 cgcagttgta accactgact tacgaccttc tctggcaaag gagtttgttt ctctggtgtg 124920 ggaccgactg atcggggatt ttgctactgg attgcaggtg caggttgaaa gtctccagaa 124980 catggtgaag ggagagaaag acgtctattt tgccaaggaa ataaaggaga aaaaagaacg 125 040 ccttcgtaaa actctctcta cagaggttca acagaaagtg tttgataaat tggtctgcca 125 100 actggcagag gctttgacag aagaagagct gagatacgcg atcttccaag agaagattac 125 160 gatcaagatt catggggtag cctcccagct cgaagcggct tttgaagagg cggtgggaga 125 220 ggcctaacct gaaaaaggag gtcttttgaa acttacgctg gaacaactca acaaaatctt 125 280 tcctaatgga gcgaaggctg gcagaaatgc caagtttatt ggtcctttga acgatttgtt 125340 tgagaagggt ggtattaata ctgtcaaccg cattgccggt ttcctctccc aaatcggggt 125 400 ggagtccgca gagttccttt ataccagaga gcttggaaac aatgcctact ttaataagta 125 460 tgataccgga ccaattgcaa agcgacttgg caatacacca gaaaaggatg gtgacggagc 125520 taagtacaag ggacgtggtc tgatccaagt caccgggctt gcaaactaca aagcttgtgg 125580 taaagcctta gggttggatc tcgtcaatca ccctgaatta cttgaacagc cgaaatatgc 125640 agttgacagc gctggttggt actggaacat gagaaacatc aacgccgctt gcgatgctga 125 700 tgatatcacc aaaatcacca agctggtaaa tggcgggact aaccacctcg cagaaagaac 125 760 cgcatactac aaaaaggcaa aatctgttct aacctcttaa ggagaaccac atgggaagaa 125820 gcaaagaggc tcgtgcaacc aaactcagcg ttcgccagca acaacgtgct gagagacaag 125880 ccaagcacca ccctaaattc gatgaggaaa ggaatagcgc tccaccgctg actcctctga 125940 atgacaagca gcaagattac cttcacaagt tgcaaacttg caatattgtt atcgcaaaag 126000 gtatcttcgg tacaggtaaa acttacctgg catcggccta cgctgctgat ctgctccgta 126060 agaatgaact cgacaagatc attgtcgctc gcccttatgt gcagacgggt aaaacctccg 126 120 gcttcaaacc gggaacatcg ttggaaaaac tcttcccgta tgttcgtaac atgttagaca 126180 ccatccgtaa acgtatgggc gacggtgcct attacaatgc gcttaaagat ggtctgaatg 126 240 ggcgtattga agttcaggaa ttggaaagca tccgtggtcg ttcattcgat gaaagaagct 126 300 atctcctgat cgacgaagcc cagcagagta ccccagagga aatgttgagt atcatcacac 126360 gtatctctga caactgtaca ctcgtggtca tgggggatgc ctctcagaaa gatatccacg 126420 gaatctccgg tctggaatgg gtggaagatt tcctgagccg gaacgggatc gcgggtgtgg 126480 gtattgtaaa cttcgacaac ccagatgatg acatcgtccg tggtggtatg gttcgtgaca 126540 ttgccaaggc gttaatcgcc gaccgtgcag aaggacgcta tactccactg gcttcgtaac 126600 ggaggattat ggcttattat acaggcgtgg ggtcgaggga gacccctcct gaggttatca 126660 gcatcatgga agatgctggt ttccgccttg caaggtgcgg attcaccttg agaagtggaa 126720 aagcgggtgg cgcagatgaa gcattccagg tcggaatgca aaaatattac gaatctcttg 126780 acaatgggaa gcaagaagag tatcgtacac atttggcgga gatctatatc ccctgggatg 126840 gatttgcatc tgacaatgac aatctctggg atttctggga ttatccttta gattatcttg 126900 attatctgat tcccgaccaa aaggttgtac gtgaggcact agttgaggag attcatccta 126960 attttgaagc tcttaaaaga aaaagaggag cttttgcgct ccattctcgt aatgtgcatc 127020 aagtcttggg ggccaatatc ctcgatccac gtccctctgc attttgtttg tactatgcca 127080 aagaagatag gaacggaaat cctaagggag gtactgcaac cgcagttaat ttagccagaa 127 140 agtacggagt tcgggttctt aacctgaaca cacctgataa actagccttg ttggagaggt 127200 tcttaagatc cttggaggaa aaacgtggca tccagatttc gcgataagct taataattct 127 260 tattgtctcg ttaaagttga tgggcagggc tggtcagttg gtaaaatcgg taacaaagtg 127320 attttcatta cttacaagga tggcgggatg aaaaacatct gtaacacaga cgatactgat 127380 ttattcagat acttcctgga atccattgag taccaaagta agagagagtt attcgttggt 127440 gacaaggtca acgttgacaa gttcggaccg tactatgtgg tagatatcgg tcaccgtgag 127500 aaagacggga gtattaagta ccttatagct cgataggagg agtatgacag ttagtattca 127560 tgggattctt tcccatcgga gactgatgga actgaagaat tgtggagtcg tcgagcctga 127620 atttttcgag tccgaggtga caaagtatta caatctctat ctaaaggttg tggctgaatc 127680 actttataga atgaatgacg ggttctttac ccggatgatt tatagccgtt ccgctgccga 127740 gcgggatgcc tcttggatgt tcccggatcg tcgtgacctg ttggaacatt tgatttacct 127800 agatggaaaa tctcagtacg tgagtttgac caaagaagag cttaaccact ttacgctgtt 127860 gcatcaagcg gcagtagcct cagaacgcgc caagagggta ctcctgtgct ttaagtacag 127920 cgaccaagtc cttgtggatg atgattcagg gttcaatata gactggttgt tacggaatgc 127980 atatacatta cgacaactga ttgtagacgc gaatggggag acacaagatg cagaataacg 128040 acaaaaagaa ttactttggc tttggcggtg gttttggtgg ggaaggttct ttctgctatc 128 100 caatgccctc tcatgagcat gtgatctata ttcatgattt ggattatatg gaagatcatt 128 160 tcaataaatt gcaacaaata cgtcaagcca acccagacga tatggtgcgt gttatcatca 128 220 acacttacgg tggacgtgta gatatcgcaa tggcttatgt tagtgcgatg cgcgagagtc 128280 aagcaactgt agttacccat gcagaggggc aggtgtgttc tgctggaaca atcttatggc 128340 tggcttctaa agagcgaact gtcgccccga tgacggaatt tatgttccat aactaccagg 128 400 gcggggcatt tggtgatggg gctaatattt atacccaggt gctgttctat aaacaacact 128460 tcgatcgctt aatcgattat ttctacaaag gtgtattgac cgacggggag atcaacacaa 128520 tcaaaggtgg cgggcaggtg tggctggatg aagttgagat cacgaaacga acccgcgcag 128580 tgattttgga tgataaaaat atcgaaagga tgaaatccgg taaaaatccg atcgtaaccc 128640 ctgttggtgt gaaagatacc cagaaagagg acactgttac tggagatcct gaccgcagtg 128700 ttgtcctgaa ggtacatgtc gatggtgaga ctttctcgtt ggatgtgaga aacctgaagg 128760 cctctgattt tgatatcttc aacattgatg agctgcaaag catcctgtca caggttgggg 128820 ctattgcaca aggggaagaa aaggcactgg agattacctc tcgtgatcgc caagcactaa 128880 tcgaagctct cctgaccgca ggtgaagtta tcatcgatac ctttgggaat gccgagtaat 128940 gagtgctcct ctgaagaaaa agggggaacg tagggaccat gacgtatatg aaacccctga 129000 atgggccgta caggcccttt tggatgttat ccctattaac ccctcatgga catacctgga 129060 accttgtaga gcgtctggga ggttctataa tcacatgcct ctcggttcag cttgggggaa 129120 attcgtgaag gtgtggatta tctcaatacc gattacccaa atcatgttga ttgcatcatc 129180 accaacccgc catattcatt ggcccaagag tttgtgacaa aagcgcttga cgatgcagat 129240 gtcgtgatta tgcttttgcg gttagggttc cttgagagta tggcgagatg ggagttttgg 129300 aaacaaaacc ctttagatca ccttattatt ctgtccaaga ggccctcttt taccgacgat 129360 ggaaaaacag atggttctgg gtatggttat tttatatggg acaaacatgg gaggttagga 129420 cttgaaaagc cgatctactg ggcacagcca gatggaagcc attaaaagat acctcagatt 129480 agagggtgca actgtttatt ggagaaagtt ggaaggggat ctaaccagaa cagagcgccg 129540 tcacaacact ttgttttctg gtaaggtggc tggagcatta aacaggaaga ctgggtatag 129600 gataatccag ttgcaaggtc ttcattacag agagcatgtt gtggtctttt tcctgcatca 129660 cggaagatgg cccgaaagta tactggacca taagaacggt aacaaacttg acaaccatcc 129720 aagcaactta agggaaagcg accattcaaa aaatgcacag aactcaaaaa cttcaactag 129780 aaacacctct ggtgtgcgtg gtgtaagttt caataagtta cgcaagaaat ggaaggtcaa 129840 ggttaccctt gagggggttg attatcatgg tgggtggttt gataaatttg aggatgcaaa 129900 atcaaaagct atttctatgc gtaaagaatt gcacaaggag aacttgagag atgatgagtg 129960 ccgcaagcaa gatgcggggg atcgcagaaa tcgcaaacgc agcaatcccc cccgagatga 130020 accagttgta cgacaacatg gtggagggga tccaccaatg tgccaagaag ggacttttgg 130080 ggatggggat ggtgatagat cttccggatc acctgcttga ttatttgcct catattattg 130 140 ctgatcttcg tggtggaggt ttcgaggttg atgtcgtaga agttgaaccc tctatgcaag 130 200 gcattagagc acgattgtat attacatggt aaacccgctt cggcgggttt tttagttttt 130260 gtacttgact tcctgcacag cttcaattat gcttctcgta ttagaggaga ttgctatgaa 130 320 attctacatt tatcaccgtc ctatgcatac catcaaattc aaagagtaca tgggcgatct 130 380 gatccatgtt tcttgtgaag agaaagattt tagcccggat ggggagcaat ggaaaattaa 130440 acgttgcaat cgtcctgagg ccgtgtataa tcgattgaac aaaatgctag cttctggtgg 130 500 cgtcccttca gatggtattt atccactatc cgacaaacgc tcacttaagg atctggtttc 130560 ttatatgaat acttggggga gacacaatga ttaataaaat ctataccgtt gttagagatc 130620 tgtgcagtga agttgtggga acatcttcta ctgttggaca aattgtaaca gcagtcgtag 130680 caatacctgc tgggacagag atggctattt attccgagga taagttgtgc gggactgcac 130740 gcactagtcg ggatgtctac ttaaccacgg gcggaggatc aagaacttta cactttggta 130 800 aggttgttga tcgtacattc gtcgtgcgta ttggtggtac agtgtacgaa ggtaacgatg 130860 tgtataccgc agaagagctg gagattactg aatgaatctt tacgcaaagc ttactaaccc 130920 gaatgcgggt tggccttatg atgagaaacg agcaaaagag tttttgaaaa ctcatgatga 130980 ggaagaaatt ctctctgtgc ttgaagttgc tattggtcgt agcagcacag ccataactct 131040 caatgagcac ggaaacggct ggaacagtgt tcagtttaca tttttcgttg aaggtgaaaa 131 100 tggtcttgaa gagtacgata tcttcatgaa taaaaacaat cttccccaaa tttataaaac 131 160 ttacgtgata tggtgatact atgaaagtaa ctgcatttgt gaaatatgat ctgtatccgt 131 220 attacactgt tgttttgggt gacctgcaag aaaattttga tgtgaaaacg gcatctggca 131280 catacaatcg cgaaaaggtc ctccatgtga ggccgtcaca tgagatagat ggtcatagga 131340 atacccttat ttccattaaa aaagaccacg atcttctttt acggaaatta aaggttgact 131 400 tgttgaagaa gaacggtata cacttcatca acacagacaa tttctaagga gaaaagatga 131460 aagtatatct ggtaggtggc gctgttcgtg atggtctgct gggtcgtcca gttcatgacc 131520 gtgattacgt ggttgtgggt gcaacacacg aagagatgat tgaaaaaggt ttcacccagg 131580 ttggcgctgc tttcccggtg tacttgcatc ctgaaaccaa agaagaatac gcactggccc 131640 gtactgagcg caaaacgggt gagggccata ctggctttga gaccttcttc agcccggatg 131700 taactctgga agaggattta tcgcgtcgtg acctgacgat caatgcgatg gctaaagaca 131760 tggagacagg atttatcatt gacccgttca atggtatgca tgacctgtcg aatatgattc 131820 ttcgtcatac tacgtcggcg ttcatggatg acccgctgcg tattctgcgt cttttccgtc 131880 ttaagtcgca gttgggtgag agttggtctg ttgatcatga aacatacaca cttatgttta 131940 ataatcgtca ccgtcttgcg gagattagcc ctgagcggaa atggaaagaa atggaaaagg 132000 ccttaaattc caaaaacttc aataattacg cctaccacat gtcgattatg ggtgaacttc 132060 cagaactgga tgccctacgt ggagtagagc agccaccaga acatcaccct gagggagacg 132 120 ctttcattca tacgttgatg tgtctgcaac aggccgataa aaccttttgc tctcctcagg 132 180 tgaaatttgc ggtgctgtgt catgactttg gaaaggcgat cactttccgt aagtacggta 132 240 atctcctcgg tcatgaagag gctggtcttg atcctgtgcg gacgctgtgc agtcgaattc 132 300 gagttcctaa cgaattcagg gatattgcac tgtacgtgac agagcaccat actcgtgtgc 132360 attgcatttt gggccgtggg aataataaag gaatcaagcc acgttccatg atgaagcttt 132420 tcgaagccgc aggtaacgtg gctagtcaga agacacagga taaggtgttt gccttagcag 132480 acgcttgttt ctgcgatgcc cgtggtcgtg gtgccaccca cgcagacaag gaatacccgc 132540 aaggaaaaat tctccttgat gctttcgagg cggttgtaaa tacggacagc aaggcggtat 132600 cttccgcaat gctagagaaa ggcaaaagcg gtaaggagat cggtgaggcg atccgtgttg 132660 cacgtatcga tgcaatccgt aatgttctta aggagagacc atgaaacttg taagtcacga 132720 agatttcaac ttgtggtgga taagacgctc tccaaagaat actatagacg cgaaggcaga 132780 gtatgctcga cttgtggcga gatgtgatta cccggcttgg gaattcctta agttcttgga 132840 aaaagaggcg aacaacttta ggaccagaaa tgaagggaaa aggaaatttc ttgtgtggaa 132900 aaatggagag cttcctttcc gcatagagaa ggtggaaatc ttcgatataa ctgagtatgg 132960 gactgatcac gcaatcagct tcaaaggaat ttcttgggct actctgtttg agagaacgct 133020 gctcaaccat gcgttggcaa gacttttcaa cctagcagat aggctcacgg aaaaagatga 133080 aaaactgctt gaacttgaat ctttcaaaca gaccagagat gaacttgggg attggctgga 133 140 ggcgcagaac aatgtctaag gacaaagaag agtacaccta cgagaaacat catttctttc 133200 tggacaaaca tgcagggaag caagtttgtg catggtgcgg tttagtagcc ctgcgtaaca 133 260 aggccacaga ctggtgtatc gaaaaaggtt gtaattatcg cttgcatcca agctacaagg 133320 gtgctatgtt taaatacaca gagttcttca aaaaaggata gaaaaatgaa ttatcttgat 133380 gacgttgtac tccctgtatg gagatttatc tttaataacg cagccttgct ggttgtcgtt 133440 ctaagtgtct tggctggatt gtgtgttggt ctcgtttatc gtgcagagga cgacacagta 133500 tgggataaat atggaattcc agcgttaata gctgttatgt gcggtttatt ccttccggta 133560 atcatagggc ttggggttat gcttcttccc gcatttatat tccttgccat aactgcggcc 133620 ataggattgg ggatgtttct tctggttaag tttgtgaagg aaaggaaagg gaaatgattt 133680 ttgccattat ttatattgtt ttcggtatca tcacagcagt ggcgataatt tatcacatcc 133740 ttcgtgaaca agatttactg agggtcgaag atattttaat ttccctgatc tgtggtgttt 133800 tttggtggtt agctatttta tgtgccattt gtggttgggt agggaagcat ctgaatagta 133860 ggacagttgt gtacaggaga aagaaataat gaagacacgt atgtattgcg tagtaaatca 133920 atatattgca ggtatccatg ccggaattca gtccgctcat gcgatcgctg aggtattccg 133980 tgactacacc cctgccaaga caaaggcagg taagttagta ttggaatggg ctgatgaaga 134040 taagactatc attgttctta atggcggtta tcagtcaagc cttcaatccc tgtgtgaaaa 134 100 gctgatccct gtttcagcta cgtacccgtg ggcctcgttc tgcgaggaaa aggatgctct 134 160 taacggggca atgacggcag ttgctgttgt gctaccagag tatatgtaca atccacaata 134220 catggaagtt gcggatctcg tataccgacc aggtcaactg tcaggaccac aaattgcgaa 134280 tcagtatcgt gatgagatgg gaaatgttat ccacaactat acccaagtgg agaaagacct 134340 gattaccatg atcaaatctt tccgactgaa aggagaatag catgaatgat gttcgtggcg 134 400 atactcttaa ggttggcgac tctgtttata tttatttcgg gtacaatgaa ctaaaacccg 134460 gcattataaa gcagatccgg ggtaagctag ccaaggtgtt ggttgatgca taccctaacc 134520 ggaaagaaga cgagagtcgt tactctttgt ctaagtggaa acctggtatc tgcatgatca 134580 aggcggaaga gcctactggt tattatccag atgaggtgat ccttctgctt gaagagatcc 134640 gccgtctgcg tgacgaagcc ccgatgaata aagatggtct gccaacaaag caactgtgtc 134700 agggactcct gaacttttgg gatatgaaac gcccgatgaa actggtaacc tcctaaggag 134760 agatgatgga aaatttcgaa gtgatgcgat gccactcagg aagtttggct tatggcacaa 134820 atctgccaac tagtgatgtg gatatccggg gtctgttctg cgcccctcct aaattcattc 134880 gcacaccgtt ctttaacatt aaagagcaaa cactggaaga cgaagaggat ggaaagattt 134940 atgagctgac aaacttcatg aagttgtttg ctgagatgaa tcctaacatt atcgagctga 135000 tgtttgtcga tgatgtggat atcttgcaaa cctccgaagt ttatgaatat ctacgcacaa 135060 tggctccggc gctgctgaca agtaaggtcg cattttcctt ctctggctat gcgatggcac 135 120 agcttaagcg tattcgcggt catgataagt ggatcagcaa tcctcagcca gaggcaaagc 135 180 ctacgcaaaa ggagttcttc cgcttagtcc acaactatag tgagaacgag ttccttgctg 135 240 gggcaattaa acatgatcgc ttcatggaag caatgaacaa tctcaacgat atgtgtatcc 135 300 ttgtacctta tgggaacgat atctatgggg tgatggaaaa cttcagtagc tcagggatgt 135 360 tcaatgctga cggttcaatt cgccatgttg actatcagca actttctgat tctgacaagc 135420 ggagaaaacc tgtctttatt gtcaaatatt tggcagagga acacaaacag gccaaagaga 135480 agcatcgtaa ctattggaca tggaaacaga accgaaatga agttcgtcac cagctcgaag 135 540 ttgattttgg ttatgacacg aaacatgcga tgcaccttgt gcggctgatg cgtatggcag 135 600 aagagattct ttctgatggg aaggtcctcg tgaagcgtcc tgatgctcag gaactcctcg 135660 atatccgggc tggtaagtgg actcttgacg aactgctctc atgggctgac gagaaggacc 135 720 attatatccg ggaagatttg tacaaaaaga cacagcttcc taaaatggcg gatcttgacc 135780 tgtttgccag ggttctcatg acggctcaag atatgtgttg gagtaaactg gtatgattga 135840 agcgctggta gggatatttg gtgttgcata ttcaatcatg gccgtggtat actcaatcag 135900 gatggaaaag gacacagtcc tgaagcaaat ctataaggcc aagacggatc gggattggtc 135960 tgaaatttgt tttgccatcg gttttgcatg gcccttcggg gccttaatcc actatgttat 136020 gaggagaaga aatgcgacag cttgagttta tgggtagaat ggtagaactg atttcagaat 136080 ggcaatcaga atataaaatg cacaggaatc tctccgaaga gcctgagaac tggcccgaca 136140 ccagagatca ggaagattgg atggaggatt tctttgtttg gctacaatgt aaggggtata 136200 cagtatgagt tatggtcttc tcactccaga acaggcaaag attatgagag aaagatacta 136260 tgcccagcaa ggcatcgaga aagttgtctg gccttctccc ggtgataccg ggactgtgaa 136320 gtgcttgcac gacgcttgtc cgaattgtgg tggcacgggt gtcagaaaag atggcactgg 136380 tttatgcgtt cacggcatct cttgtccttg tccgaagtgc agttttaagt gctgaatcgt 136440 ccctatctta tatgataacc ctgtttttca tgataaaatg gatctatcat taagatagga 136500 ggttagtatg tttcaaaaaa ttgtacgtga acaccctatc cttcgagagc actggcatac 136560 tctgctggaa aagggtttta tagaaaactc aaaaggttgc atcgctctcg taagggagcc 136620 tgtgacagaa gaacgagttc tcgtcataag ggatgccaaa aacggcatcc ttttttctat 136680 caaagttggt cgtctggacg tcactagggg ttcaaatacc ataagaccaa caacttacac 136740 ttttcgtgtt ggagacatgg ggaagctaga tccagaacat ctggaagagg cctttgatag 136800 ttatgaggga ttcgaagcct ctattcgcga tctctataga tcgctggata gaattatcaa 136860 tgaacacaag aaaacgctcg ggataaaata ccgagtaaaa gactggttca ggaatgccaa 136920 caaccgctgg ttccttctgg cggcagttct ctacggcctg ttaacggtat ttctgacctt 136980 gcattaagag gagattctta tgagagatcg tcaggagtat tatcgtcagt atgccgctcg 137040 tcgtcgtgag attgaccgtc agcggcgttc tacaccagaa ggtaaagcag aacaacttcg 137 100 tatccgtctt gcccgtattg aagcagagaa acgcgccacc cttcatagtg agtgggatga 137 160 gtttgtcagg gatgaggctg atcacttatg ctctgttcgt tgtgaagata ccggtattaa 137220 gtgggaacca gatcatatgt ttccgctaag ggcaacaaaa gtatccggcc ttaactgtgg 137280 tgataatatc caagtgatac ctgcaactct caacaggaag aagaaaaacc gtatgattta 137340 taccgaaagg aatgaatggt tgaaagatgt atagaagaaa cccggcgatt gccgggtttt 137400 tttttattga cctttggata gcttttctat cacgagatga tctgaatcgt ccaggtgcat 137460 caagtgatca gatcggatat catgcagata tgggagtcca tcaacgtgac aaagaaacca 137520 ggattcgtta cgagggtaat atccatttac acctaggatg gtcttctcca gcacaagaca 137580 gcgttttcca ttaaggatat tatcctcaga gaatccatac aacagacaga ttgaatcaac 137640 acaaacctta tggtctggct cattacgatc aggcatacca ctatcttcta atttcagcat 137700 tttttatctc caaagttaag ttcgccattc aacttttgta cacggtgagg gagaatttcc 137760 tgccaccacc aatccttctc gtgaagacga taagacacat aaacctcaac ggtatcctcg 137820 tccttacgga cggttctggt gtagatatcc cgaatggttg cttcgaattg accgtccaca 137880 aggacgacct cgtaaatttt gtacttatct tgttcaagaa cttcttctga cattttatct 137940 cctatttgat tctttttcca ccatgttttt cataaatggc gatgactttt tctaagtcta 138000 gcacagaagc tgtttcagtc cacccatctt tcatgtattc ctttgatata aagcctgtga 138060 ctactctttt tttacattcc ttctctgctt ttttgcactt ttctgctgag gagaactccc 138 120 agacacctat gttcttagcc ttggccctgt tcatggagtt catctttgat atcctatatt 138180 ttgggtcttt actgataccg aatttaaaac cttgctcacc ctcgataaga tggatatatg 138240 aaaacttttg gtttttaccc gcacattcag gacacccaca ccccttatgg taaagtcggt 138 300 cgaagttagt aataaaatca ccatgttttt ggcacctcat cgtgatctct agtgtctttg 138360 cattcttgcc ttcataccca cttacccaac caataaattc caaatttctc gccacgctct 138420 caatctggaa aattctttgt ctttcagtgt atctatagct actactacac ctgcacgcga 138480 gtttcccgct ttcaaaatcg gatctcctca tagtgaacca accatcacaa atacccgcct 138540 ttgaaaactc atccttgcga caaacagggc acttgtaatc gatatacaca tggtggcctt 138600 ttgcattggt tctttcagat tctctgactt tatacacccc ttttttcgcc gtctttgctg 138660 ggccagctct ggaaattttc ttagggggtt tttccatctt atgtgggacc ccctttaggc 138720 ctctctcctt tttcaggttt ttgaactcca ctactttacg attaagcagg cttctgactt 138780 cgttcttccg ataattataa actaacgcgg gaacttcgaa acctccgaac tcttcgtagc 138840 ctacaataca aaccatataa attagtaccc cagatcttct atattgtgtg gtaacatggt 138900 gttccaaaac aaccccctcc atattttttt taaatgatta taccaacaaa tttggtatca 138960 atcaactgtt gacaagacct ctctttctgt cataatgcca agataaacaa tttcaaagga 139020 gaaatcatgg ggaggtgtat gaaaaaattt tgcatctatg gccgggtaag cgttgacaac 139080 ggctggtatt tgtgcaaatc tggtgtcggt gaagacgagc ttgccaagtg gcttgcctat 139 140 taccgtaaaa cttggcgcta tgttaagggg atttcttacg atgaataaat ttaggctaaa 139200 atgtcaaggt ggacgttggt gggtgcagga aaaattcttt gggttcctgt ggctgaccat 139260 ttggaattcc tctttgacga aagaaagtgc aatggcaaag attgcagagc acgtccagga 139320 aaaagaggat gaatgcattt actatccaac acgggaagag attatcgccg cagtctctgc 139380 taagatgatg cgaccaggcc caccaccagc ccctccttcc aagccttaat gaggataaaa 139440 actatgattt acgatgattt ggttttgata aagtctgctc tgaagaaatc tcggagcaat 139500 ggaatttact tcagggaccc gaagtggttg cagggcattt acatctacct ttctcaaaaa 139560 ggtagtctgt acatagtcta cagcttggga accatgtttg gaggagaggg ctatcgatgc 139620 actcagatta atgagcacgc cctccccagt ctcggccaca actttgagat ttgggaaggt 139680 tctatatgat tgaaatctgg aaaaccctgg gatgtgtttt catgtccttt gtgatgggaa 139740 ccgggctggc gcaaactgcc gagtcccatg attttgtcgg gatgttgctg tttggaatgg 139800 cctttgcctt ctggactaac ctctcccttc tacgtatttt tggcgatcat taggagttaa 139860 tatgggaagc acttttactg tccaatactg gacaaacgcc cacgaaggtg agtataaata 139920 ttatgtattc tggcagggcg aaagctttga cgaggcaatt cggcagatgg taaaatgtaa 139980 ggacaaaggc tacggttgcg taaagatgga gtggcggtga atgaagatag aaagcaagaa 140040 tatggctatg ggaacgcagt ctttacagca gatggcaaga gattaccaat ggtgggaccc 140 100 gagtgggacc cccaatggga gatcgctctc aaacgaggag gttatctttc tgaaagccat 140 160 caagaagtac accaaatggc ctttaacgaa agtagccgaa atgatgggaa tctcatacca 140 220 caaggttata aaggccgtcc gattaagaga tcctgtgctg gttccttcaa gaatcccgga 140280 atacttttat gaggttacag ggatggtgaa gggtaaaaat ggtcccgaag gtactgctaa 140340 gaacatcaag gctggaaatc aagcactcag tgacgaggat gtcgcggtca taagggaact 140 400 gcacaagaga ggatatgctg tggaagacat cgccacagcc tttaataaaa gtgtcggcta 140460 caccggaaca cttatcaggg gcgatagtcg ccacttcttg tccgcagacc ctgaacgggt 140520 gaaagaaaga atggtcacct ttgaaaaact gctgggtgat cgcgtatagg cgcgaagcgc 140580 cgcgccgtcc aaatccagta cccccaggta caccggggcc tggattttgc cgtcgatctt 140640 tttgtgaagg agttttcgtg ggaaatgtta agaaggcatt agagcatctt gatacaacgc 140700 gccccggtat ccggtgggtg gagggtgttt ctcatgggta tcggggcgca cttgcatatg 140760 tagaaaatat tcgtgcagcg gcagaggctt gttggtacat tcaggacatg gctgactgga 140820 caaagcgctt tgctttgaaa gaaaagacga aggccattgt tggtcatgat cgtattcttt 140880 ttggaaaaga gccttgacac ctcacggata gtaatatatc ctcagggtat ctaatcaaga 140940 ggaggagcta tgaatttctg gataatgcga gcgatcgtcc gcgatcactt caatgcggaa 141000 agaagcggtg tttatgagaa cctcggatgt ctgcctttta tcctgaaagt tgtagccatc 141060 gttctcatca tcgtggtact taatcacttt ggtctttggg agtagagtat gtttacttta 141120 gtatttacgt ttttcctgtt cattttgaac gcagtttgtt gtgggttgca gggattaaca 141180 cttctgcttc gtgaaaaaga agacccgttt gtttttcctg gtatcatgat gattgcccat 141240 gcattccttt cagcatggat gttcaatgtt tggtgggaga tggcaccatg aatatcttta 141300 cagatgcacg ggcctacaca ccgcttacac ctgaagagcg tgagtggata aagcaggaga 141360 ttgctgaggc ggaggcccag ctaaccgacg aagtgtggat cgaaaactac gtgaagggtt 141420 gccacgaaga tggcatgacc tctttcgatc gcgagctggt catcatgtgc attcaggccg 141480 acctttatgg tatgaagaga tgcctgaagc ataactatgt gattctttgg tgagggaaat 141540 tatggcattc actattattg cgttaattac aaatattgtt ggcggggtat tccacaccat 141600 acttgcttcc gacggggaaa ataagttttc ggcaattgtc tctgcgatca attggttctt 141660 ggttggtgct ctgctagtca ttcttctcca tgaggtggct gcatgacgtt caacgaagta 141720 cgctacatcc gtgtgtatgg ggaataccaa aacccggagg ttattcgagt atctaaggat 141780 ggtcgtaact ggtatcttgt aacaacagat gatgatgagg tcgttgagaa attcccgaaa 141840 gatttactcc tcacaatcag cttgtacgac aagtggatga atagtcttct atggagttcg 141900 ctcgtctacc atgcagagga taactcttcc cttgatgggt ctgacattgt gaaacacttc 141960 tggcgctgca cagattacat ggagcggatt attgcttcaa aactcaaaga agtctttcct 142020 tggtgtgagt gctcaaatga aagatattga taagatgggg acagagacat gcccacactg 142080 tggtggctac tctgccagta ccgttatcac agaacgttac atccttactg tagactttac 142 140 tggcctacca tatggtcaag ctgataataa gattgtgtct ggagggaaga ggtttatttg 142200 tgatacctgt gggaaggatg tgtctaagtt tatacccaaa ctggagatat taaaatgaaa 142 260 gttaatgtta cagaaaaaga aaaaacaagt gtggccctcc actctctctc ggtcggggat 142320 ggttttctgt ttgatggtta tccgcacatg gtgtgtgaat caaccatagg atattataaa 142380 gggttcatgc aggccgttaa tcttcgtaac gcgagcattg tagcgttgcc gctaatgcag 142440 caggtccagc caaccaacat ctctgtggag tacacagtgt gaataccctc aacacctaca 142500 caaaagtctt ccatttctgg tggcaaaatc tgggaagacc cgatatcggc tcaaaggatg 142560 aggcacttcg aggttggaaa gactgtatgc ttaagcagca cgaaatcaat gacaagggga 142620 gtatcctccg gggaacagat acttattgcc tagggtggaa cgccgctgtc gagtttattc 142680 ttggggagaa ttacgatgac aaactatcat gttttgaatg aatgggttct tgcaaacaga 142740 aaagggcctt tgttggttat ttacaaaaag ggttcaaaga gtattgaaga atgccttgag 142800 cttaccccgc tgaaaagtct acatttccac cacgacggag aggacctgag aaacagggtc 142860 tgcggctacc gggtgggtgg catcattgtt gaaccgggtg caaattttgg caaacacaac 142920 cttcgttatg ccatctcccg tcttcggtct gaggataatg tctacctttt cctgatggat 142980 gaggaacatg aggacatatt ggaagatatt tttgaagaat actacgagag tgccacaaac 143040 aaagagatgg ttgagagcct ccgtagccag atcgtaatct atgacccgga gtgcttctat 143 100 ggcctacaga acatttgagg aatggaacgc ccgtgggagg atcgtcaaaa agggcgagaa 143 160 agctatgggt cacctccttg acggaactgc gcttttcggg aaagagcaga ccaaaggcaa 143 220 aaagagccgt gactggggag aggctgatct gggtgatgca ccagactcct ggtacatggg 143280 tgggcctgag gattattatt aatgaaacat atcccgttga agaagtgcaa acctataacc 143340 tactgcaaat tctgcaaagc catcggcatc cgcagacgct gcacatttat gacgaaatac 143400 caaccgccgt ggggactgcg tgactggtac aagcattacg cctgtgatga acacaaacac 143460 ctgattgaag accccgaccc acggggaatc atggaagctg ctgcaaagaa ccctgctcca 143520 ccacaaaagg ttgcacggga tgagcactac acagaagccg actaccagac ctggatgaga 143580 ctgtaggaga cagaatgtat aaaacaccaa aattgaaaaa acttaaaaac tttccttgga 143640 tcgaggatgt tgacggactc aaggcctact gtaagaaaat agcagagggg tctgagaacg 143700 cgcaaaaaga ggattgcgag gtctttattc taccaggtaa tttgcacgat atctgcatca 143760 aatacaccgc aggagatgta tttcatttag cagaaattat ggctacatgg ttcaaagagc 143820 ataagcatga agcagttatt attttgaagc aatacagaga cacaacatcc cccaactttt 143880 ggacaacagt cttaaatgta tacagatctc ctgctagtgt agctatggac ctttgggaag 143940 gctatgttcg tgatgaagag ggagaggccg tcaggatttt ggatatgtac gacaccagta 144000 aggaagaatg gattacaaaa gaggcgtata gcagaactgg ggtaatgaaa attcgaggtg 144060 gtttcaccac acaataagca cacaacaagg gagcctgaag aggccccttt tttattactt 144120 aaaacccttg acctgaagtg ccgcacacat tatactcctc atatcaacta cagaggagac 144180 acacaatatg tccacaacac aacaggccat tgagaaatgg aacggcacag tcccacatat 144240 caatatacct tcaccactgc tggatattca ggcataccat atgagtgcag gcgagtcaac 144300 attgtgtatc ataggtattt tattggccct catggtggca cttcgatctt tatatgatgc 144360 agtcacaggg gaatcgccat tgtgcaaggc ggggaatact tgggtctgca tggcgacaac 144420 ctataccgca ggtcatttga tttggctggc aatccaatac tggtgagtgg ttgaatatgg 144480 aactgatagt tcttttggtg ttgctgattg ttgccatagt ggtggtagtc cttgctatcc 144540 gcaccttatt cggagacgac gatgataatg acaataacac ccctccaacg ggacaggcca 144600 cccaggcaat gatgcggacc acaaaaaggg gttgacctga agaggcaacc ctgttatcat 144660 ttacacagca ataggtgctg aggctgcacg aaacaatcac catccttgcg taggaggttg 144720 taaatgagag tgcttctcat tgtactgcgt actcatttca ttaacacaca atctgaaggg 144780 actcccagac atgtcggtaa agataaagcc cctacagggg cctgcacata tcaaggatgc 144840 cctcataatc ctcgcattta aatgtttctg tgaaaccatc agggagccat tctttaaggc 144900 acaggcttct ctcgaatgat gactttatct tagattctac ctcaagagcc tcttctcttg 144960 aatcaaactt aaatacatta acaatgttgt gcttgaacat tcccaatttt tcctgctgtt 145020 tctttctgtt cgaggtgtta ttagaaatac caaccttaag gcatttgaaa aatggtgagt 145080 atagctcttg aatatacagt tctgttggtt tagtcacctc tcgtttaacc accttcctag 145140 gtttcttctt atgtttcatc tctacatgct tcttttcttg agcacaaact gaggggtacg 145200 aatgaagatc tttaaaatca acagttttta agcacaatac atccactgcc tgctctacac 145260 ttgttattgc cagatcctta ccgcagttag gacaagtgcc taacatacgg gtaattatag 145320 ggtctggggc acctgtaata ttaagtagca tagcgaggtg gatgtctgcc tgctcccaga 145380 attcctttct taccttagct atctcgttat cgaactcaat ctttaaggag ttcattttag 145440 atacaaggtg gtggttattt ttatagtttt cctgttgccg caattctctt tccgcacagc 145500 gcaggtgcat ctctacacaa acatactcca aagatccctg ttcattcacc accccatatc 145560 tccacccaca ccttgtgagg tatggaatag gctccccaac acaagaggtt atacctatat 145620 cctcagccag ttgaagcatc tcttttcttg tagccttgtc aaatatttgt ttaagacaag 145680 acctggattc attggtaaat acccagttgt caggttcgag ccatcttttt tccagtttta 145740 aaatcttatc gaccatcttc attttgtatc tcctccgtag gtatagtagt aactatagca 145800 ttttacacac aaattacaac ccccgccccg tggggaaatc aaaacatgcc tctgccgaaa 145860 atatcccttg ccgaaaaata tctgtctggg tgttttggag cattcgtact gtctgaggtg 145920 cta 145923

Claims (11)

폐렴 간균(Klebsiella pneumoniae)에 특이적인 사멸능을 갖는, 서열번호 1로 표시되는 염기서열로 이루어진 박테리오파지 KP12 (수탁번호 KFCC11737P).
Bacteriophage KP12 (accession number KFCC11737P) consisting of a nucleotide sequence represented by SEQ ID NO: 1, having a specific killing ability against pneumonia bacilli ( Klebsiella pneumoniae ).
 제1항에 있어서, 상기 박테리오파지 KP12는 정이십면체의 머리를 가지며 수축성의 꼬리가 있는 형태인, 박테리오파지 KP12.
The method of claim 1, wherein the bacteriophage KP12 has a regular icosahedral head and has a contractile tail, bacteriophage KP12.
 삭제delete 제1항에 있어서, 상기 폐렴 간균(Klebsiella pneumoniae)은 베타락탐계 항생제 내성 세균인 ESBL(Extended-spectrum beta-lactamase)-폐렴 간균(Klebsiella pneumoniae)인, 박테리오파지 KP12.
According to claim 1, wherein the pneumonia bacillus ( Klebsiella pneumoniae ) is a beta-lactam antibiotic-resistant bacteria ESBL (Extended-spectrum beta-lactamase)-pneumococcal ( Klebsiella pneumoniae ), bacteriophage KP12.
 삭제delete 제1항의 박테리오파지 KP12를 포함하는, 항생용 조성물.
A composition for antibiotics comprising the bacteriophage KP12 of claim 1.
 제1항의 박테리오파지 KP12를 포함하는, 사료 첨가용 조성물.
A composition for feed addition, comprising the bacteriophage KP12 of claim 1.
 제7항의 사료 첨가용 조성물을 포함하는, 사료.
A feed comprising the composition for feed addition of claim 7.
 제1항의 박테리오파지 KP12를 포함하는, 소독제.
A disinfectant comprising the bacteriophage of claim 1 KP12.
 제1항의 박테리오파지 KP12를 포함하는, 세척제.
A detergent comprising the bacteriophage KP12 of claim 1.
 삭제delete
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110217756A1 (en) 2010-03-02 2011-09-08 Nina Tsao Newly isolated bacteriophage specific to klebsiella pneumoniae
US20110217268A1 (en) 2010-03-02 2011-09-08 Nina Tsao Therapy or prophylaxis of klebsiella pneumoniae infections with a lytic bacteriophage specifically against the k. pneumoniae
JP2015523850A (en) 2012-05-04 2015-08-20 バイオコントロール リミテッドＢｉｏｃｏｎｔｒｏｌ Ｌｉｍｉｔｅｄ Therapeutic bacteriophage composition

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110217756A1 (en) 2010-03-02 2011-09-08 Nina Tsao Newly isolated bacteriophage specific to klebsiella pneumoniae
US20110217268A1 (en) 2010-03-02 2011-09-08 Nina Tsao Therapy or prophylaxis of klebsiella pneumoniae infections with a lytic bacteriophage specifically against the k. pneumoniae
JP2015523850A (en) 2012-05-04 2015-08-20 バイオコントロール リミテッドＢｉｏｃｏｎｔｒｏｌ Ｌｉｍｉｔｅｄ Therapeutic bacteriophage composition

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