CN113577219B - Traditional Chinese medicine composition for treating diabetic enteropathy and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating diabetic enteropathy and preparation method thereof Download PDF

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CN113577219B
CN113577219B CN202111025338.9A CN202111025338A CN113577219B CN 113577219 B CN113577219 B CN 113577219B CN 202111025338 A CN202111025338 A CN 202111025338A CN 113577219 B CN113577219 B CN 113577219B
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CN113577219A (en
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杨宇峰
石岩
徐畅
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Liaoning University of Traditional Chinese Medicine
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/487Psoralea
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/79Schisandraceae (Schisandra family)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
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    • A61K36/88Liliopsida (monocotyledons)
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Abstract

The invention provides a traditional Chinese medicine composition for treating diabetic enteropathy and a preparation method thereof, wherein the raw materials of the traditional Chinese medicine composition comprise red ginseng, astragalus root, sealwort, liquorice, atractylodes macrocephala, psoralea fruit, nutmeg, Chinese yam, coix seed, lotus seed, amomum fruit, myrobalan and schisandra fruit. The traditional Chinese medicine composition treats the early-stage diabetic enteropathy by taking blood sugar and intestines and stomach conditioning as multiple targets and adopting the concept of warming kidney and spleen, consolidating the constitution and stopping diarrhea. The traditional Chinese medicine composition provided by the application can effectively treat the diabetic enteropathy, has a good treatment effect, a short treatment course and low cost, can greatly reduce the physical pain of patients suffering from the diabetic enteropathy, improves the life quality of the patients, and can reduce the economic burden of the patients.

Description

Traditional Chinese medicine composition for treating diabetic enteropathy and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating diabetic enteropathy and a preparation method thereof.
Background
The diabetic enteropathy belongs to diabetic gastrointestinal autonomic neuropathy, and is one of chronic complications of diabetes. The clinical manifestations of diabetic enteropathy are intractable diarrhea, intermittent diarrhea, unformed stool, intermittent constipation, alternate occurrence of constipation and diarrhea, dyschezia, etc. With the change of diet and living habits of people, the population suffering from the diabetic enteropathy shows a trend of increasing year by year.
At present, most of western medicine treatments for the diabetic enteropathy are blood sugar control aiming at the primary disease and symptomatic treatment, and the clinical curative effect is not exact and the disease is easy to recur. Most of the traditional Chinese medicine prescriptions proposed by the traditional Chinese medicine dialectical treatment scheme aiming at the treatment of the diabetic enteropathy in clinic by traditional Chinese medicine are complicated and have different clinical curative effects, and the diabetic enteropathy still lacks the traditional Chinese medicine dialectical treatment standard recognized in the industry.
Disclosure of Invention
The invention provides a traditional Chinese medicine composition for treating diabetic enteropathy and a preparation method thereof, aiming at solving the problem of poor treatment effect of the traditional Chinese medicine preparation for treating diabetic enteropathy.
The invention provides a traditional Chinese medicine composition for treating diabetic enteropathy, which is prepared from raw materials of red ginseng, astragalus root, sealwort, liquorice, bighead atractylodes rhizome, malaytea scurfpea fruit, nutmeg, Chinese yam, coix seed, lotus seed, fructus amomi, myrobalam and schisandra chinensis, wherein the traditional Chinese medicine components in the traditional Chinese medicine composition have the following characteristics:
red ginseng: has effects of invigorating primordial qi, invigorating qi, nourishing heart, and tranquilizing mind, and can be used for treating asthenia due to long-term illness, and deficiency of both qi and blood. It also has effects in regulating nerve, and treating cardiovascular and cerebrovascular diseases and endocrine system diseases.
Astragalus root: sweet in flavor and slightly warm in nature; has effects in invigorating qi, consolidating superficial resistance, expelling toxic materials, expelling pus, promoting urination, and promoting granulation; can be used for treating qi deficiency, asthenia, chronic diarrhea, proctoptosis, spontaneous perspiration, edema, uterine prolapse, chronic nephritis, albuminuria, diabetes, and unhealed wound.
Rhizoma polygonati: sweet in taste and neutral in nature; has effects in invigorating qi, nourishing yin, invigorating spleen, moistening lung, and invigorating kidney; can be used for treating deficiency of spleen-stomach qi, asthenia, stomach yin deficiency, xerostomia, dry cough, hemoptysis, deficiency of essence and blood, soreness of waist and knees, premature gray hair, and internal heat with thirst quenching effect.
Licorice root: mild in nature and sweet in taste. It enters heart, lung, spleen and stomach meridians. Has the effects of invigorating spleen and replenishing qi, clearing away heat and toxic material, eliminating phlegm and stopping cough, relieving spasm and pain, and harmonizing the medicines. Modern pharmacological research shows that the lipid-lowering tea has obvious effects of lowering lipid and protecting cardiovascular.
White atractylodes rhizome: bitter taste, warm and pungent nature; has effects of invigorating spleen, invigorating qi, eliminating dampness, promoting diuresis, arresting sweating, and preventing miscarriage; can be used for treating spleen deficiency, anorexia, dyspepsia, diarrhea, edema, spontaneous perspiration, and threatened abortion.
Fructus psoraleae: bitter taste, pungent and warm; has effects in invigorating kidney, supporting yang, arresting spontaneous emission, reducing urination, treating lumbago due to kidney deficiency, frequent micturition, infantile enuresis, kidney leakage, warming spleen, relieving diarrhea, and relieving asthma; can be used for treating kidney deficiency, sexual impotence, soreness of waist and knees, psychroalgia, spermatorrhea, enuresis, frequent micturition, and diarrhea before dawn due to spleen and kidney yang deficiency.
Nutmeg: pungent taste and warm nature; has effects of warming spleen and stomach, activating qi-flowing, relieving diarrhea with astringents; can be used for treating deficiency-cold of spleen and stomach, chronic diarrhea, abdominal distention and pain, anorexia, and emesis.
Chinese yam: sweet in taste and neutral in nature; has effects in invigorating spleen, tonifying lung, reinforcing kidney, and replenishing vital essence; it can be used for treating spleen deficiency, anorexia, chronic diarrhea, lung deficiency, cough, asthma, spermatorrhea due to kidney deficiency, leukorrhagia, frequent micturition, and diabetes due to deficiency heat.
Coix seed: sweet and light taste, cool in nature; has effects in promoting diuresis, removing dampness, invigorating spleen, relieving diarrhea, relieving arthralgia, expelling pus, removing toxic substance, and resolving hard mass; can be used for treating edema, loempe, dysuresia, spleen deficiency, diarrhea, rheumatism, spasm, pulmonary abscess, and intestinal abscess; wart, cancerous protuberance.
Lotus seed: sweet and astringent taste, mild nature; has effects in invigorating spleen, relieving diarrhea, stopping leukorrhagia, invigorating kidney, arresting seminal emission, nourishing heart, and tranquilizing mind; can be used for treating diarrhea due to spleen deficiency, leukorrhagia, spermatorrhea, palpitation, and insomnia.
Amomum fruit: pungent taste and warm nature; has effects in eliminating dampness, stimulating appetite, warming spleen, relieving diarrhea, regulating qi-flowing, and preventing miscarriage; can be used for treating damp stagnation, abdominal distention, inappetence, deficiency-cold of spleen and stomach, emesis, diarrhea, vomiting, threatened abortion, and threatened abortion.
Myrobalan fruit: bitter, sour, astringent and neutral in nature; has effects of relieving diarrhea with astringents, astringing lung, relieving cough, lowering fire and relieving sore throat; it can be used for treating chronic diarrhea, dysentery, hematochezia, proctoptosis, cough and asthma due to lung deficiency, chronic cough, pharyngalgia, and hoarseness.
And (2) Chinese magnoliavine fruit: sour and sweet in taste, warm in nature; has effects in astringing, arresting discharge, invigorating qi, promoting salivation, tonifying kidney, and calming mind; can be used for treating chronic cough, asthma, nocturnal emission, enuresis, frequent micturition, chronic diarrhea, spontaneous perspiration, night sweat, thirst due to body fluid consumption, internal heat, diabetes, palpitation, and insomnia.
In the traditional Chinese medicine composition for treating the diabetic enteropathy, the preparation raw materials of the traditional Chinese medicine composition comprise, by weight, 10-20 parts of red ginseng, 25-35 parts of astragalus membranaceus, 30-40 parts of rhizoma polygonati, 5-15 parts of liquorice, 15-25 parts of bighead atractylodes rhizome, 10-20 parts of fructus psoraleae, 10-20 parts of nutmeg, 10-20 parts of Chinese yam, 5-15 parts of semen coicis, 10-20 parts of lotus seed, 5-15 parts of fructus amomi, 5-15 parts of myrobalan and 10-20 parts of schisandra chinensis. Most preferably, the raw materials for preparing the traditional Chinese medicine composition comprise, by weight, 15 parts of red ginseng, 30 parts of astragalus membranaceus, 35 parts of rhizoma polygonati, 10 parts of liquorice, 20 parts of bighead atractylodes rhizome, 15 parts of fructus psoraleae, 15 parts of nutmeg, 15 parts of Chinese yam, 10 parts of semen coicis, 15 parts of lotus seed, 10 parts of fructus amomi, 10 parts of myrobalan and 15 parts of schisandra chinensis.
Based on the traditional Chinese medicine composition for treating the diabetic enteropathy provided by the embodiment of the application, the application also provides a preparation method of the traditional Chinese medicine composition, and the method comprises the following steps:
s01: soaking radix Ginseng Rubra, radix astragali, rhizoma Polygonati, radix Glycyrrhizae, rhizoma Atractylodis Macrocephalae, fructus Psoraleae, semen Myristicae, rhizoma Dioscoreae, semen Coicis, semen Nelumbinis, fructus Amomi, fructus Chebulae, and fructus Schisandrae chinensis in cold water for 20-30 min.
Soaking the selected red ginseng, astragalus membranaceus, rhizoma polygonati, liquorice, bighead atractylodes rhizome, fructus psoraleae, nutmeg, Chinese yam, semen coicis, lotus seed, fructus amomi, myrobalan and schisandra chinensis in cold water for 20-30 minutes. The amount of cold water is 1-3 cm higher than the mixture of Ginseng radix Rubri, radix astragali, rhizoma Polygonati, Glycyrrhrizae radix, Atractylodis rhizoma, fructus Psoraleae, semen Myristicae, rhizoma Dioscoreae, Coicis semen, semen Nelumbinis, fructus Amomi, fructus Chebulae, and fructus Schisandrae.
S02: decocting the soaked Ginseng radix Rubri in a decocting container for 2 times; decocting with strong fire for 20 min each time, and mixing the two decoctions to obtain Ginseng radix Rubri decoction.
Decocting the soaked Ginseng radix Rubri in a decocting container for 2 times. During each decoction, after the decoction is boiled with strong fire, the decoction is continued for 20 minutes with small fire, and the decoction and the dregs are obtained by filtration. Decocting the residue with strong fire and then with slow fire for 20 min, and filtering to obtain decoction and residue. Mixing the decoctions obtained by the two times to obtain the red ginseng medicinal juice for later use. Preferably, the medicine decocting container is an earthen pot, an enamel ware or a stainless steel ware.
S03: decocting the soaked radix astragali, rhizoma Polygonati, Glycyrrhrizae radix, Atractylodis rhizoma, fructus Psoraleae, semen Myristicae, rhizoma Dioscoreae, Coicis semen, semen Nelumbinis, fructus Amomi, fructus Chebulae, and fructus Schisandrae in a decocting container for 2 times; after boiling with big fire each time, decocting with small fire for 20 minutes, and mixing the two decoctions to obtain a mixed decoction.
Decocting the soaked radix astragali, rhizoma Polygonati, Glycyrrhrizae radix, Atractylodis rhizoma, fructus Psoraleae, semen Myristicae, rhizoma Dioscoreae, Coicis semen, semen Nelumbinis, fructus Amomi, fructus Chebulae, and fructus Schisandrae in a decocting container for 2 times. The decoction method is the same as that of Ginseng radix Rubri, and is not repeated here. Radix astragali, rhizoma polygonati, liquorice, bighead atractylodes rhizome, fructus psoraleae, nutmeg, Chinese yam, semen coicis, lotus seed, fructus amomi, myrobalan and schisandra chinensis are decocted for two times to obtain mixed medicine juice.
S04: the red ginseng medicinal juice and the mixed medicinal juice are mixed to obtain the traditional Chinese medicine composition for treating the diabetic enteropathy.
Mixing the red ginseng medicinal juice and the mixed medicinal juice to obtain the traditional Chinese medicine composition for treating the diabetic enteropathy. The important mixture is divided into two parts, and is taken once in the morning and evening.
The technical scheme provided by the embodiment of the invention can have the following beneficial effects:
the invention provides a traditional Chinese medicine composition for treating diabetic enteropathy and a preparation method thereof, wherein the raw materials of the traditional Chinese medicine composition comprise red ginseng, astragalus, polygonatum, liquorice, bighead atractylodes rhizome, fructus psoraleae, nutmeg, Chinese yam, coix seed, lotus seed, fructus amomi, myrobalan and schisandra chinensis. The traditional Chinese medicine composition treats the diabetic enteropathy by taking blood sugar and stomach conditioning as multiple targets and adopting the concept of warming kidney and spleen, consolidating the constitution and stopping diarrhea. Radix astragali is used as the monarch drug in the formula, and is used for greatly tonifying spleen qi and tonifying deficiency of middle-jiao energy, and simultaneously red ginseng is used for greatly tonifying primordial qi, rhizoma atractylodis macrocephalae is used for tonifying spleen and eliminating dampness, and radix glycyrrhizae preparata is sweet in flavor and can also tonify spleen and replenish qi. Aiming at the main pathogenesis of the spleen-qi deficiency of diabetes, the rhizoma polygonati is used for nourishing yin and moistening dryness. The fructus psoraleae is matched with the fructus psoraleae for warming the kidney and the spleen, the nutmeg for warming the spleen and the stomach and relieving diarrhea with astringents, the spleen and the kidney are used for treating both diseases, so that the fire in the vital gate is sufficient, the spleen yang is strengthened and transported, the force of warming yang and astringing intestines is supplemented, and the schisandra chinensis is used for astringing the body fluid and relieving thirst in an acid astringing way. The Chinese yam has the effects of tonifying qi and spleen, the coix seed has the effects of excreting dampness and stopping diarrhea, and the lotus seed, the fructus amomi and the myrobalan which are medicines for strengthening and controlling diarrhea are added to play a role in invigorating yang, promoting diuresis and stopping diarrhea together. So this recipe has the efficacies of warming kidney and spleen, consolidating the constitution and checking diarrhea. The traditional Chinese medicine composition provided by the application can effectively treat the diabetic enteropathy, has a good treatment effect, a short treatment course and low cost, can greatly reduce the physical pain of patients suffering from the diabetic enteropathy, improves the life quality of the patients, and can reduce the economic burden of the patients.
It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the invention, as claimed.
Detailed Description
According to the clinical characteristics of early diabetic enteropathy patients, the traditional Chinese medicine composition treats the diabetic enteropathy by taking blood sugar and regulating intestines and stomach as multiple targets and adopting the concept of warming kidney and spleen, consolidating the foundation and stopping diarrhea. Clinical tests prove that the traditional Chinese medicine composition can effectively reduce blood sugar and achieve the effect of coordinating intestines and stomach.
The following description will be given by way of specific examples of the Chinese medicinal composition for treating diabetic bowel disease provided by the present application, but this does not limit the scope of the present application.
Example 1
The embodiment of the application provides a traditional Chinese medicine composition for treating diabetic enteropathy, and the traditional Chinese medicine composition comprises 15 parts of red ginseng, 30 parts of astragalus membranaceus, 35 parts of rhizoma polygonati, 10 parts of liquorice, 20 parts of bighead atractylodes rhizome, 15 parts of fructus psoraleae, 15 parts of nutmeg, 15 parts of Chinese yam, 10 parts of semen coicis, 15 parts of lotus seed, 10 parts of fructus amomi, 10 parts of myrobalan and 15 parts of schisandra chinensis according to parts by weight.
Based on the traditional Chinese medicine composition for treating the diabetic enteropathy provided by the embodiment of the application, the embodiment of the application also provides a preparation method of the traditional Chinese medicine composition, and the preparation method specifically comprises the following steps:
s101: soaking the selected red ginseng, astragalus membranaceus, rhizoma polygonati, liquorice, bighead atractylodes rhizome, fructus psoraleae, nutmeg, Chinese yam, semen coicis, lotus seed, fructus amomi, myrobalan and schisandra chinensis in cold water for 20-30 minutes. The amount of cold water is 1-3 cm higher than the mixture of Ginseng radix Rubri, radix astragali, rhizoma Polygonati, Glycyrrhrizae radix, Atractylodis rhizoma, fructus Psoraleae, semen Myristicae, rhizoma Dioscoreae, Coicis semen, semen Nelumbinis, fructus Amomi, fructus Chebulae, and fructus Schisandrae.
S102: decocting the soaked Ginseng radix Rubri in a decocting container for 2 times. During each decoction, after the decoction is boiled with strong fire, the decoction is continued for 20 minutes with slow fire, and the decoction and the dregs are obtained by filtration. Decocting the residue with strong fire and then with slow fire for 20 min, and filtering to obtain decoction and residue. Mixing the decoctions obtained by the two times to obtain the red ginseng medicinal juice for later use. Preferably, the medicine decocting container is an earthen pot, an enamel ware or a stainless steel ware.
S103: decocting the soaked radix astragali, rhizoma Polygonati, Glycyrrhrizae radix, Atractylodis rhizoma, fructus Psoraleae, semen Myristicae, rhizoma Dioscoreae, Coicis semen, semen Nelumbinis, fructus Amomi, fructus Chebulae, and fructus Schisandrae in a decocting container for 2 times. The decoction method is the same as that of Ginseng radix Rubri, and is not repeated here. The preparation method comprises the following steps of decocting astragalus membranaceus, rhizoma polygonati, liquorice, bighead atractylodes rhizome, fructus psoraleae, nutmeg, Chinese yam, coix seed, lotus seed, fructus amomi, myrobalan and schisandra chinensis twice to obtain a mixed medicine juice.
S104: mixing the red ginseng medicinal juice and the mixed medicinal juice to obtain the traditional Chinese medicine composition for treating the diabetic enteropathy. The important mixture is divided into two parts, and is taken once in the morning and evening.
Example 2
The embodiment of the application provides a traditional Chinese medicine composition for treating diabetic enteropathy, which is prepared from raw materials of, by weight, 10 parts of red ginseng, 25 parts of astragalus membranaceus, 30 parts of rhizoma polygonati, 5 parts of liquorice, 15 parts of bighead atractylodes rhizome, 10 parts of fructus psoraleae, 10 parts of nutmeg, 10 parts of Chinese yam, 5 parts of semen coicis, 10 parts of lotus seed, 5 parts of fructus amomi, 5 parts of myrobalan and 10 parts of schisandra chinensis.
Based on the traditional Chinese medicine composition for treating diabetic enteropathy provided by the embodiment of the application, the embodiment of the application also provides a preparation method of the traditional Chinese medicine composition, and the specific method refers to embodiment 1.
Example 3
The embodiment of the application provides a traditional Chinese medicine composition for treating diabetic enteropathy, and the traditional Chinese medicine composition comprises 20 parts of red ginseng, 35 parts of astragalus membranaceus, 40 parts of rhizoma polygonati, 15 parts of liquorice, 25 parts of bighead atractylodes rhizome, 20 parts of fructus psoraleae, 20 parts of nutmeg, 20 parts of Chinese yam, 15 parts of semen coicis, 20 parts of lotus seeds, 15 parts of fructus amomi, 15 parts of myrobalan and 20 parts of schisandra chinensis according to parts by weight.
Based on the traditional Chinese medicine composition for treating the diabetic enteropathy provided by the embodiment of the application, the embodiment of the application also provides a preparation method of the traditional Chinese medicine composition, and the specific method refers to the embodiment 1.
Example 4
The embodiment of the application provides a traditional Chinese medicine composition for treating diabetic enteropathy, and the traditional Chinese medicine composition comprises 8 parts of red ginseng, 28 parts of astragalus membranaceus, 32 parts of rhizoma polygonati, 12 parts of liquorice, 22 parts of bighead atractylodes rhizome, 16 parts of fructus psoraleae, 16 parts of nutmeg, 18 parts of Chinese yam, 12 parts of semen coicis, 17 parts of lotus seeds, 9 parts of fructus amomi, 9 parts of myrobalan and 16 parts of schisandra chinensis according to parts by weight.
Based on the traditional Chinese medicine composition for treating diabetic enteropathy provided by the embodiment of the application, the embodiment of the application also provides a preparation method of the traditional Chinese medicine composition, and the specific method refers to embodiment 1.
In order to illustrate that the traditional Chinese medicine composition for treating the diabetic enteropathy provided by the embodiment of the application can be used for treating the diabetic enteropathy and has good curative effect, the embodiment of the application provides an example of clinical cases.
Clinical examples
Li A certain, female, 62 years old. The patient is admitted to the hospital with the symptoms of intermittent dry mouth and thirst for more than 20 years and aggravation accompanied by diarrhea for 3 d. The patient was diagnosed with type 2 diabetes 20 years ago in local hospitals, and now, 30 noh-ari refills, 32u early and 30u late, were injected subcutaneously before meals to lower blood sugar. The blood sugar is controlled to be 13-14 mmol/l in fasting state, and 20mmol/l in 2h after meal. Diarrhea symptoms appear in nearly 3 days, and the patients are watery and defecated, and are diagnosed without treatment by medicines. The symptoms are as follows: thirst, weakness, bitter taste in mouth, poor eyesight, pain in hands and feet, pruritus of the whole body, poor appetite, insomnia, scanty urine and loose stool, 6 to 8 times a day, dark tongue with thin and yellow coating and deep and thready pulse. History of the past: history of diabetic peripheral neuropathy, and history of hypertension. Physical examination: BP: 120/80mm Hg, spirit, lucidity, clear respiratory sound of both lungs, no smell of dry and wet rale, dull heart sound, regular heart sound, no smell of pathological noise in auscultation areas of valves, soft abdomen, no tenderness, rebound pain and muscular tension, no edema of both lower limbs and palpable fluctuation of arteries of both feet and back. Auxiliary inspection: c-reactive protein, CRP: 12.30 mg/L. Potassium, K: 4.03 mmol/L. Uric acid, UA: 426 μmol/L. Urine series: white blood cells, WBCs: 57.0/. mu.L. Urinary protein, PRO: 2+. Nitrite, NIT: +. Urobilirubin, BIL: 1+. Stool routine + occult blood: occult blood test, B-QX negative. Glycated hemoglobin, HbA 1C: 10.30 percent. Urinary microalbumin, MALB: 62.4 mg/L. Blood cell analysis: RBC: 3.58X 10 12 And L. White blood cells, WBC: 10.71X 10 9 And L. Glucose, GLU: 10.38 mmol/L. And (3) urine culture: escherichia coli, ECO:≥10 8 cfu/L. Culturing without mould growth, and culturing: without abnormality, urinary color Doppler ultrasound: no abnormality was found. And (3) diagnosis: diabetes and diarrhea. The therapeutic principle is as follows: to replenish qi, raise yang, invigorate spleen, remove dampness and stop diarrhea. After 7 doses of the traditional Chinese medicine composition provided in example 1 are taken, diarrhea is reduced, but edema of both eyelids is seen. After the dosage is changed, the diarrhea is cured after 7 doses of the medicine are continuously taken, and the diarrhea symptom is not caused again after the follow-up visit for half a year.
In conclusion, the traditional Chinese medicine composition provided by the embodiment of the application can effectively treat the diabetic enteropathy, has a good treatment effect, a short treatment course and low cost, can greatly reduce the physical pain of patients suffering from the diabetic enteropathy, improves the life quality of the patients, and can reduce the economic burden of the patients.
Other embodiments of the invention will be apparent to those skilled in the art from consideration of the specification and practice of the disclosure herein. This application is intended to cover any variations, uses, or adaptations of the invention following, in general, the principles of the invention and including such departures from the present disclosure as come within known or customary practice within the art to which the invention pertains. It is intended that the specification and examples be considered as exemplary only, with a true scope and spirit of the invention being indicated by the following claims.
It is to be understood that relational terms such as "first" and "second," and the like, may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. The present invention is not limited to the precise arrangements that have been described above, and various modifications and changes may be made without departing from the scope thereof. The scope of the invention is limited only by the appended claims.

Claims (5)

1. The traditional Chinese medicine composition for treating the diabetic enteropathy is characterized by comprising the following raw materials in parts by weight: 10-20 parts of red ginseng, 25-35 parts of astragalus membranaceus, 30-40 parts of rhizoma polygonati, 5-15 parts of liquorice, 15-25 parts of bighead atractylodes rhizome, 10-20 parts of fructus psoraleae, 10-20 parts of nutmeg, 10-20 parts of Chinese yam, 5-15 parts of semen coicis, 10-20 parts of lotus seed, 5-15 parts of fructus amomi, 5-15 parts of myrobalan and 10-20 parts of schisandra chinensis.
2. The traditional Chinese medicine composition for treating diabetic enteropathy according to claim 1, wherein the raw materials for preparing the traditional Chinese medicine composition comprise the following components in parts by weight: 15 parts of red ginseng, 30 parts of astragalus membranaceus, 35 parts of rhizoma polygonati, 10 parts of liquorice, 20 parts of bighead atractylodes rhizome, 15 parts of fructus psoraleae, 15 parts of nutmeg, 15 parts of Chinese yam, 10 parts of coix seed, 15 parts of lotus seed, 10 parts of fructus amomi, 10 parts of myrobalan and 15 parts of schisandra chinensis.
3. The traditional Chinese medicine composition for treating diabetic enteropathy of claim 1, wherein the preparation method comprises:
soaking radix Ginseng Rubra, radix astragali, rhizoma Polygonati, radix Glycyrrhizae, rhizoma Atractylodis Macrocephalae, fructus Psoraleae, semen Myristicae, rhizoma Dioscoreae, semen Coicis, semen Nelumbinis, fructus Amomi, fructus Chebulae, and fructus Schisandrae chinensis in cold water for 20-30 min;
decocting the soaked Ginseng radix Rubri in a decocting container for 2 times; decocting with strong fire for 20 min each time, and mixing the two decoctions to obtain Ginseng radix Rubri decoction;
decocting the soaked radix astragali, rhizoma Polygonati, Glycyrrhrizae radix, Atractylodis rhizoma, fructus Psoraleae, semen Myristicae, rhizoma Dioscoreae, Coicis semen, semen Nelumbinis, fructus Amomi, fructus Chebulae, and fructus Schisandrae in a decocting container for 2 times; decocting with strong fire for 20 min, and mixing the decoctions to obtain mixed decoction;
the red ginseng medicinal juice and the mixed medicinal juice are mixed to obtain the traditional Chinese medicine composition for treating the diabetic enteropathy.
4. The traditional Chinese medicine composition for treating diabetic enteropathy of claim 3, wherein the decocting container comprises an earthen pot, an enamel ware or a stainless steel ware.
5. The traditional Chinese medicine composition for treating diabetic enteropathy according to claim 3, wherein the amount of cold water is 1-3 cm of the height of the mixture of the red ginseng, the astragalus membranaceus, the polygonatum sibiricum, the licorice, the bighead atractylodes rhizome, the fructus psoraleae, the nutmeg, the Chinese yam, the coix seed, the lotus seed, the fructus amomi, the myrobalan and the schisandra chinensis.
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