CN113577155A

CN113577155A - Medicine for treating burn and its preparation method

Info

Publication number: CN113577155A
Application number: CN202111020605.3A
Authority: CN
Inventors: 刘质友; 刘质顺; 刘成功; 刘成伟
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-09-01
Filing date: 2021-09-01
Publication date: 2021-11-02

Abstract

The application provides a medicine for treating burns and a preparation method thereof, and the medicine comprises 37-43 parts of rheum officinale, 36-43 parts of coptis chinensis, 18-22 parts of cortex dictamni, 150-168 parts of gypsum, 2-6 parts of keel, 17-24 parts of talc, 6-9 parts of cinnabar, 2-6 parts of catechu, 6-10 parts of yellow lead and 3-8 parts of borneol. Weighing the medicines according to a certain proportion, grinding and screening to obtain fine powder, coating the fine powder on the burnt part of a patient when in use, and wrapping with vaseline oil gauze. The medicine prepared by the application has high cure rate, and after scientific material selection and proportioning, the medicine composition has the effects of clearing heat and detoxicating, inhibiting bacteria and sterilizing, relieving swelling and pain, removing slough and promoting granulation, so that the wound surface is protected quickly after the medicine is taken, local sterility is formed to control infection, meanwhile, the slough and promoting granulation effects of the medicine prepared by the application promote the wound to heal quickly, the wound surface is sealed and protected in time, and the wound surface is naturally promoted to heal without external interference, so that no scar or pigmentation exists after healing.

Description

Medicine for treating burn and its preparation method

Technical Field

The application relates to the technical field of medicines, in particular to a medicine for treating burn and a preparation method thereof.

Background

Burn generally refers to tissue damage caused by heat (including hot liquid, steam, hot gas, flame, electric energy, chemical substances, radioactive rays, glowing metal liquid or solid, etc.), mainly refers to damage of skin or mucous membrane, and serious people can also damage other tissues. The main clinical symptoms after skin burn are: redness, swelling, pain, burning sensation, localized redness and swelling, weeping, blisters, and severe pain of the skin. If the burn is not treated in time, infection can be further caused, so that the burn needs to be treated in time, but most of the existing medicines for treating the burn have complex components, complex preparation, high cost, slow effect and long pain time of patients.

Disclosure of Invention

Aiming at the defects of the prior art, the application aims to provide the medicine for treating the burn and the preparation method thereof, the medicine is prepared by processing raw materials of rhubarb, coptis, cortex dictamni, gypsum, keel, talc, cinnabar, catechu, yellow lead, borneol and the like, and can quickly treat the burn and relieve the pain of a patient.

The technical scheme adopted by the application is as follows:

the medicine for treating the burn comprises the following raw medicines in parts by weight: 37-43 parts of rheum officinale, 36-43 parts of coptis chinensis, 18-22 parts of cortex dictamni, 150-168 parts of gypsum, 2-6 parts of keel, 17-24 parts of talc, 6-9 parts of cinnabar, 2-6 parts of catechu, 6-10 parts of yellow lead and 3-8 parts of borneol.

Further, the medicine for treating the burn comprises the following raw medicines in parts by weight: 40 parts of rheum officinale, 40 parts of coptis chinensis, 20 parts of cortex dictamni, 160 parts of gypsum, 4 parts of keel, 20 parts of talc, 8 parts of cinnabar, 4 parts of catechu, 8 parts of yellow lead and 5 parts of borneol.

Further, the medicine for treating the burn comprises the following raw medicines in parts by weight: 41 parts of rhubarb, 39 parts of coptis chinensis, 20 parts of cortex dictamni, 155 parts of gypsum, 5 parts of keel, 21 parts of talcum, 7 parts of cinnabar, 4 parts of catechu, 9 parts of yellow lead and 5 parts of borneol.

Further, the preparation method of the medicine for treating the burn comprises the following steps:

(1) washing radix et rhizoma Rhei, Coptidis rhizoma, cortex Dictamni Radicis, Catechu, and Plumbum Preparatium, and air drying;

(2) weighing rhubarb, coptis chinensis, cortex dictamni, gypsum, keel, talc, cinnabar, catechu, yellow lead and borneol according to a proportion, and putting the mixture into a traditional Chinese medicine ultrafine grinder to grind for 12-18 min;

(3) the ground coarse powder was sieved with a 120-mesh sieve to obtain a fine powder.

Further, a method for using the medicine for treating burn comprises the steps of coating fine powder on the burn part of a patient and wrapping the burn part with a vaseline oil gauze.

The beneficial effect of this application lies in:

the traditional Chinese medicine adopted by the application is scientifically prepared and proportioned, wherein: catechu has certain inhibition on staphylococcus aureus, pseudomonas aeruginosa, diphtheria bacillus, proteus bacillus, dysentery bacillus and typhoid bacillus for later use, and has obvious inhibition on tubercle bacillus for later use; plumbum Preparatium and Cinnabaris have effects of clearing heart heat, removing toxic substance and preventing corrosion, and can be used for treating skin ulcer, furuncle and pyogenic infections, and inhibiting and killing bacteria; gypsum Fibrosum, Os Draconis, and pulvis Talci have good therapeutic effects in clearing away heat and toxic materials, treating burn, stopping bleeding, and resisting allergy; the rhubarb, the cortex dictamni and the coptis have the effects of cooling blood and removing stasis, can reduce wound bleeding and promote blood stasis dissipation; the borneol has the effects of clearing heat and relieving swelling, can relieve symptoms of swelling and pain of wounds, and is beneficial to promoting wound healing.

The medicine for treating burns, which is obtained by processing the materials according to the proportion, can be used for treating the burn wound appropriately, the wound is protected quickly after the medicine is used, local sterility is formed to control infection, meanwhile, the damaged capillary vessel is closed quickly due to the scab film formed by fibrin exuded by an organism and tannin rich in the plant medicine in the application, and the exudation and the loss of tissue fluid are prevented; meanwhile, the medicine prepared by the application has the effects of removing the necrotic tissue and promoting tissue regeneration, promotes the wound to heal quickly, seals and protects the wound surface in time, and naturally promotes the tissue regeneration and heals without external interference, so that no scar or pigmentation exists after healing.

Detailed Description

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

Example 1

A medicine for treating burn is prepared from the following raw materials in parts by weight: 40 parts of rheum officinale, 40 parts of coptis chinensis, 20 parts of cortex dictamni, 160 parts of gypsum, 4 parts of keel, 20 parts of talc, 8 parts of cinnabar, 4 parts of catechu, 8 parts of yellow lead and 5 parts of borneol. The preparation method comprises the following steps:

(2) weighing 200g of rheum officinale, 200g of coptis chinensis, 100g of cortex dictamni, 800g of gypsum, 20g of keel, 100g of talc, 40g of cinnabar, 20g of catechu, 40g of yellow lead and 25g of borneol, and putting the mixture into a traditional Chinese medicine superfine pulverizer to grind for 15 min;

Example 2

A medicine for treating burn is prepared from the following raw materials in parts by weight: 41 parts of rhubarb, 39 parts of coptis chinensis, 20 parts of cortex dictamni, 155 parts of gypsum, 5 parts of keel, 21 parts of talcum, 7 parts of cinnabar, 4 parts of catechu, 9 parts of yellow lead and 5 parts of borneol. The preparation method comprises the following steps:

(2) weighing 205g of rheum officinale, 195g of coptis chinensis, 100g of cortex dictamni, 775g of gypsum, 25g of keel, 105g of talc, 35g of cinnabar, 20g of catechu, 45g of yellow lead and 25g of borneol, and putting the mixture into a traditional Chinese medicine superfine pulverizer to grind for 15 min;

Application example

1. Irritation test:

(1) when the medicine prepared by the application is used for contacting the skin of a mouse by a single administration for 6 hours, the medicine has no irritation to the damaged skin of the complete skin of the mouse.

(2) The medicine prepared by the application is continuously applied to the skin of a mouse for 7 days, and no irritation is generated to the intact skin and the damaged skin of the mouse when the medicine is observed for 7 days.

2. Therapeutic effects

(1) Case selection

A total of 240 patients were clinically selected, 67 patients were hospitalized, and 173 patients were outpatient. 93 cases of mild burn, 74 cases of moderate burn, 48 cases of severe burn and 25 cases of very severe burn. The two groups were evenly divided and treated with the drugs prepared in examples 1 and 2 of this application.

(2) Burn diagnostic criteria: the diagnosis standard of burn is the classification standard of the degree of light, medium, heavy and extra heavy burn, and the burn is classified into four types: (1) the first and second degree burns with the total area less than 10 percent are mild burns; (2) moderate burn is caused by the I and II degree burn or the III degree burn with the total area of 11-30 percent and the area of less than 10 percent; (3) the first and second degree burns with the total area between 30 percent and 50 percent or the severe burns with the area between 10 percent and 20 percent of the third degree burns; (4) the first and second degree burn with the total area of more than 51% or the third degree burn with the area of more than 21% is the extra-heavy degree burn.

(3) Method of treatment

The application is a pure traditional Chinese medicine ointment for external application, after conventional debridement and disinfection, different amounts of medicinal powder are applied to the burn part of a patient according to different burn degrees and burn areas, the burn part is bound by a vaseline oil yarn strip, 1 time every day, 3 days are a treatment course, the patient is generally cured in 2-5 treatment courses, and the treatment course can be properly increased for severe burn patients.

(4) Standard of care

The wound surface recovers natural skin color and natural physiological function, joint parts do not contracture or deform, and skin does not leave sequelae such as keloid, pruritus and the like, so that patients can recover normal life, study and work again.

(5) The treatment effect is as follows: clinical verification of years shows that the medicine provided by the embodiment has obvious curative effect by treating 240 patients. Specific treatment data are shown in table 1:

TABLE 1 statistical treatment results

As can be seen from the table 1, the cure rate of 240 cases of burn patients reaches 91.5 percent on average, the effect is obvious, and no adverse reaction and toxic or side effect are found, which indicates that the medicine has obvious curative effect on the aspect of treating the burn patients and has good popularization value. The cure cases of the group of the particularly severe burns in the example 2 are low because the number of cases is small, and the number of patients who are not cured in a single case has a large influence on the statistical results.

The medicine prepared by the application has high cure rate, and after scientific material selection and proportioning, the medicine composition has the effects of clearing heat and detoxicating, inhibiting bacteria and sterilizing, relieving swelling and pain, removing slough and promoting granulation, so that the wound surface is protected quickly after the medicine is taken, local sterility is formed to control infection, meanwhile, the slough and promoting granulation effects of the medicine prepared by the application promote the wound to heal quickly, the wound surface is sealed and protected in time, and the wound surface is naturally promoted to heal without external interference, so that no scar or pigmentation exists after healing.

The above description is only for the purpose of illustrating the preferred embodiments of the present application and is not to be construed as limiting the present application, and all equivalent variations and modifications within the scope of the present application are intended to be covered by the present application. Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims

1. A medicine for treating burn is characterized in that: comprises the following raw medicines in parts by weight: 37-43 parts of rheum officinale, 36-43 parts of coptis chinensis, 18-22 parts of cortex dictamni, 150-168 parts of gypsum, 2-6 parts of keel, 17-24 parts of talc, 6-9 parts of cinnabar, 2-6 parts of catechu, 6-10 parts of yellow lead and 3-8 parts of borneol.

2. A medicament for the treatment of burns as claimed in claim 1, wherein: comprises the following raw medicines in parts by weight: 40 parts of rheum officinale, 40 parts of coptis chinensis, 20 parts of cortex dictamni, 160 parts of gypsum, 4 parts of keel, 20 parts of talc, 8 parts of cinnabar, 4 parts of catechu, 8 parts of yellow lead and 5 parts of borneol.

3. A medicament for the treatment of burns as claimed in claim 1, wherein: comprises the following raw medicines in parts by weight: 41 parts of rhubarb, 39 parts of coptis chinensis, 20 parts of cortex dictamni, 155 parts of gypsum, 5 parts of keel, 21 parts of talcum, 7 parts of cinnabar, 4 parts of catechu, 9 parts of yellow lead and 5 parts of borneol.

4. A process for the preparation of a medicament for the treatment of burns as claimed in claim 1, wherein: the method comprises the following steps:

5. The method of using a medicament for the treatment of burns as claimed in claim 1, wherein: when in use, the fine powder is applied to the burn part of a patient and wrapped by a vaseline oil gauze.