CN113576993A - Plant essential oil itching-relieving gel and preparation method thereof - Google Patents
Plant essential oil itching-relieving gel and preparation method thereof Download PDFInfo
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- CN113576993A CN113576993A CN202110965054.1A CN202110965054A CN113576993A CN 113576993 A CN113576993 A CN 113576993A CN 202110965054 A CN202110965054 A CN 202110965054A CN 113576993 A CN113576993 A CN 113576993A
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- essential oil
- itching
- oil
- camphor
- ethanol
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- 239000000341 volatile oil Substances 0.000 title claims abstract description 109
- 208000003251 Pruritus Diseases 0.000 title claims abstract description 30
- 238000002360 preparation method Methods 0.000 title claims description 7
- 238000001879 gelation Methods 0.000 title description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 61
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 37
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 27
- 235000011187 glycerol Nutrition 0.000 claims abstract description 22
- 241000196324 Embryophyta Species 0.000 claims abstract description 21
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims abstract description 19
- 241000723346 Cinnamomum camphora Species 0.000 claims abstract description 19
- 229930008380 camphor Natural products 0.000 claims abstract description 19
- 229960000846 camphor Drugs 0.000 claims abstract description 19
- 241000205585 Aquilegia canadensis Species 0.000 claims abstract description 18
- 235000007866 Chamaemelum nobile Nutrition 0.000 claims abstract description 18
- 244000042664 Matricaria chamomilla Species 0.000 claims abstract description 18
- 235000007232 Matricaria chamomilla Nutrition 0.000 claims abstract description 18
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims abstract description 18
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims abstract description 18
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims abstract description 18
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims abstract description 18
- 230000007803 itching Effects 0.000 claims abstract description 18
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims abstract description 17
- AJBZENLMTKDAEK-UHFFFAOYSA-N 3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-4,9-diol Chemical compound CC12CCC(O)C(C)(C)C1CCC(C1(C)CC3O)(C)C2CCC1C1C3(C)CCC1C(=C)C AJBZENLMTKDAEK-UHFFFAOYSA-N 0.000 claims abstract description 17
- RSWGJHLUYNHPMX-UHFFFAOYSA-N Abietic-Saeure Natural products C12CCC(C(C)C)=CC2=CCC2C1(C)CCCC2(C)C(O)=O RSWGJHLUYNHPMX-UHFFFAOYSA-N 0.000 claims abstract description 17
- 235000003880 Calendula Nutrition 0.000 claims abstract description 17
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims abstract description 17
- KHPCPRHQVVSZAH-HUOMCSJISA-N Rosin Natural products O(C/C=C/c1ccccc1)[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 KHPCPRHQVVSZAH-HUOMCSJISA-N 0.000 claims abstract description 17
- 229940041616 menthol Drugs 0.000 claims abstract description 17
- KHPCPRHQVVSZAH-UHFFFAOYSA-N trans-cinnamyl beta-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OCC=CC1=CC=CC=C1 KHPCPRHQVVSZAH-UHFFFAOYSA-N 0.000 claims abstract description 17
- 240000001548 Camellia japonica Species 0.000 claims abstract description 16
- 235000018597 common camellia Nutrition 0.000 claims abstract description 16
- 235000015112 vegetable and seed oil Nutrition 0.000 claims abstract description 16
- 235000014104 aloe vera supplement Nutrition 0.000 claims abstract description 15
- 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 claims abstract description 9
- 235000003097 Artemisia absinthium Nutrition 0.000 claims abstract description 9
- 240000001851 Artemisia dracunculus Species 0.000 claims abstract description 9
- 235000017731 Artemisia dracunculus ssp. dracunculus Nutrition 0.000 claims abstract description 9
- 235000003261 Artemisia vulgaris Nutrition 0.000 claims abstract description 9
- 239000001138 artemisia absinthium Substances 0.000 claims abstract description 9
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims abstract description 9
- 238000009833 condensation Methods 0.000 claims abstract description 8
- 230000005494 condensation Effects 0.000 claims abstract description 8
- 240000001432 Calendula officinalis Species 0.000 claims abstract 6
- 238000003756 stirring Methods 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 5
- 244000144927 Aloe barbadensis Species 0.000 claims description 4
- 235000002961 Aloe barbadensis Nutrition 0.000 claims description 4
- 235000011399 aloe vera Nutrition 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 3
- 238000004090 dissolution Methods 0.000 claims description 2
- 208000002193 Pain Diseases 0.000 abstract description 6
- 230000036407 pain Effects 0.000 abstract description 6
- 241000894006 Bacteria Species 0.000 abstract description 4
- 206010061218 Inflammation Diseases 0.000 abstract description 4
- 230000004054 inflammatory process Effects 0.000 abstract description 4
- 230000003467 diminishing effect Effects 0.000 abstract description 2
- 241000132025 Calendula Species 0.000 description 11
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 description 8
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 description 8
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 description 8
- 229940116229 borneol Drugs 0.000 description 8
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 description 8
- 230000000694 effects Effects 0.000 description 7
- 239000003973 paint Substances 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 231100000021 irritant Toxicity 0.000 description 3
- 239000002085 irritant Substances 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 206010052428 Wound Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 239000001525 mentha piperita l. herb oil Substances 0.000 description 2
- 235000019477 peppermint oil Nutrition 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 230000029663 wound healing Effects 0.000 description 2
- SCYULBFZEHDVBN-UHFFFAOYSA-N 1,1-Dichloroethane Chemical compound CC(Cl)Cl SCYULBFZEHDVBN-UHFFFAOYSA-N 0.000 description 1
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 206010003399 Arthropod bite Diseases 0.000 description 1
- 208000032544 Cicatrix Diseases 0.000 description 1
- 206010014198 Eczema infantile Diseases 0.000 description 1
- 241000792859 Enema Species 0.000 description 1
- 206010063560 Excessive granulation tissue Diseases 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
- 208000031888 Mycoses Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 210000000683 abdominal cavity Anatomy 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 201000008937 atopic dermatitis Diseases 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 239000010495 camellia oil Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 239000007920 enema Substances 0.000 description 1
- 229940095399 enema Drugs 0.000 description 1
- 210000001339 epidermal cell Anatomy 0.000 description 1
- 210000001126 granulation tissue Anatomy 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 239000010687 lubricating oil Substances 0.000 description 1
- 231100000067 mild irritant Toxicity 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
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- 231100000241 scar Toxicity 0.000 description 1
- 230000037387 scars Effects 0.000 description 1
- 230000008591 skin barrier function Effects 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 241000712461 unidentified influenza virus Species 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Botany (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses plant essential oil itching-relieving condensation, which is characterized by comprising the following components in percentage by mass: 0.5-1.3% of menthol, 0.8-1.2% of camphor, 3-6% of glycerol, 0.07-0.13% of aloe vera extract, 0.50-0.70% of argy wormwood leaf essential oil, 0.008-0.015% of chamomile essential oil, 0.007-0.014% of camellia seed oil, 0.009-0.012% of honeysuckle essential oil, 0.008-0.015% of calendula essential oil, 0.007-0.015% of rosin essential oil, 35-40% of ethanol, 0.16-0.25% of hydroxypropyl methyl cellulose and 100% of pure water. Compared with the prior art, the invention has the advantages that: the skin care product can retain moisture, moisten the skin and keep the skin soft and elastic while relieving pain and itching, resisting bacteria and diminishing inflammation.
Description
Technical Field
The invention relates to the field of daily chemical articles, in particular to plant essential oil itching-relieving condensation and a preparation method thereof.
Background
In daily life, a plurality of families are provided with a certain amount of medicinal oil for red swelling and discomfort caused by mosquito bites and the like, and damaged skin needs to be nursed and repaired in time; the common itching relieving water, floral water and the like can be poured out or the dosage can not be accurately controlled by carelessness, and some infants can not use the liquid due to the addition of irritant substances.
Disclosure of Invention
The invention aims to provide the itching relieving lotion which can effectively relieve itching, is convenient to absorb, is safe and has no stimulation and side effect.
In order to solve the technical problems, the technical scheme provided by the invention is as follows: the plant essential oil itching relieving gel is characterized by comprising the following components in percentage by mass: 0.5-1.3% of menthol, 0.8-1.2% of camphor, 3-6% of glycerol, 0.07-0.13% of aloe vera extract, 0.50-0.70% of argy wormwood leaf essential oil, 0.008-0.015% of chamomile essential oil, 0.007-0.014% of camellia seed oil, 0.009-0.012% of honeysuckle essential oil, 0.008-0.015% of calendula essential oil, 0.007-0.015% of rosin essential oil, 35-40% of ethanol, 0.16-0.25% of hydroxypropyl methyl cellulose and 100% of pure water.
Further, the paint comprises the following components in percentage by mass: 1% of menthol, 1% of camphor, 5% of glycerol, 0.10% of aloe vera extract, 0.60% of folium artemisiae argyi essential oil, 0.01% of chamomile essential oil, 0.01% of camellia seed oil, 0.01% of honeysuckle essential oil, 0.01% of calendula essential oil, 0.01% of rosin essential oil, 40% of ethanol, 0.20% of hydroxypropyl methyl cellulose and 52.05% of pure water.
Further, the paint comprises the following components in percentage by mass: 0.5% of menthol, 1.2% of camphor, 6% of glycerol, 0.07% of aloe vera extract, 0.7% of argy wormwood leaf essential oil, 0.008% of chamomile essential oil, 0.007% of camellia seed oil, 0.012% of honeysuckle essential oil, 0.008% of calendula essential oil, 0.015% of rosin essential oil, 40% of ethanol, 0.16% of hydroxypropyl methyl cellulose and 51.32% of pure water.
Further, the paint comprises the following components in percentage by mass: 1.3% of menthol, 0.8% of camphor, 3% of glycerol, 0.13% of aloe vera extract, 0.5% of argy wormwood leaf essential oil, 0.015% of chamomile essential oil, 0.014% of camellia seed oil, 0.009% of honeysuckle essential oil, 0.015% of calendula essential oil, 0.007% of rosin essential oil, 35% of ethanol, 0.25% of hydroxypropyl methyl cellulose and 58.96% of pure water.
A preparation method of plant essential oil itching relieving condensation comprises the following steps: dissolving menthol and camphor completely by using ethanol, adding glycerol, aloe barbadensis extract, folium artemisiae argyi essential oil, chamomile essential oil, camellia seed oil, honeysuckle essential oil, calendula essential oil, rosin essential oil and pure water, stirring at the rotating speed of 500 plus materials of 1000r/min for complete dissolution, and then adding hydroxypropyl methyl cellulose while stirring to completely dissolve the mixture to prepare the plant essential oil itching-relieving condensation.
Compared with the prior art, the invention has the advantages that:
menthol, which is used as an irritant in medicine, acts on the skin or mucous membrane, and has the effects of cooling and relieving itching; it can be used topically for relieving inflammation, pain, itching, promoting blood circulation, and relieving edema.
Camphor, which has mild irritant and antiseptic effects for topical application, is commonly used for pain relief, itch reduction and fungal infection treatment.
Glycerin, which can be dissolved with water in any proportion, and low-concentration glycerol solution can be used as lubricating oil to moisten skin (glycerine enema); people usually wear the glycerin on the skin surface exposed in the air such as hands, faces and the like in winter, so that the glycerin can keep the skin soft and elastic, is not damaged by dust, climate and the like and is dry, and plays a role in preventing the skin from being frostbitten.
The aloe vera extract is safe and non-irritant, and has certain curative effects on rough skin, dryness, infantile eczema, scars, acne and the like.
Ethanol is an important organic solvent and is widely used in various industries such as medicines, paints, sanitary products, cosmetics, grease and the like, and in the invention, ethanol is used for dissolving menthol and camphor.
Dissolving hydroxypropyl methylcellulose in water and appropriate proportion of ethanol/water, propanol/water, dichloroethane, etc., dissolving in diethyl ether, acetone, and anhydrous ethanol, and swelling in cold water to obtain clear or slightly turbid colloidal solution; the aqueous solution of the compound has surface activity, high transparency and stable performance; it is mainly used as thickener, emulsifier and stabilizer in medicine.
Borneol: 1. anti-inflammatory, antibacterial, analgesic: the natural borneol can obviously inhibit the increase of the permeability of capillary vessels in the abdominal cavity of a mouse caused by acetic acid and has an anti-inflammatory effect; can obviously prolong the pain response time and the pain response of the mouse caused by thermal stimulation, and has the function of analgesia; the in vitro direct antiviral test shows that the compound has the function of inhibiting influenza virus; 2. promoting wound healing: the borneol has the effects of resisting inflammation and bacteria, reducing the infection of bacteria to the wound of the skin and the defecation surface and promoting the healing of the wound. In addition, borneol can increase granulation tissue structure and epidermal cell regeneration, repair skin accessory organs and has stronger wound healing effect. The water soluble borneol has the effect of borneol and is easy to dissolve in water.
The plant essential oil itching relieving condensation provided by the invention has the functions of relieving pain and itching, resisting bacteria and diminishing inflammation, and can also retain moisture, moisten skin and keep the skin soft and elastic. The aloe vera extract, the folium artemisiae argyi essential oil, the chamomile essential oil, the honeysuckle essential oil and the rosin essential oil are matched to effectively exert the antibacterial and anti-inflammatory effects, protect the skin, enhance the skin barrier function and simultaneously have a good moisturizing effect.
Detailed Description
Example 1
The plant essential oil itching relieving gel is characterized by comprising the following components in percentage by mass: 1% of menthol, 1% of camphor, 5% of glycerol, 0.10% of aloe vera extract, 0.60% of folium artemisiae argyi essential oil, 0.01% of chamomile essential oil, 0.01% of camellia seed oil, 0.01% of honeysuckle essential oil, 0.01% of calendula essential oil, 0.01% of rosin essential oil, 40% of ethanol, 0.20% of hydroxypropyl methyl cellulose and 52.05% of pure water.
Example 2
The plant essential oil itching relieving gel is characterized by comprising the following components in percentage by mass: 0.5% of menthol, 1.2% of camphor, 6% of glycerol, 0.07% of aloe vera extract, 0.7% of argy wormwood leaf essential oil, 0.008% of chamomile essential oil, 0.007% of camellia seed oil, 0.012% of honeysuckle essential oil, 0.008% of calendula essential oil, 0.015% of rosin essential oil, 40% of ethanol, 0.16% of hydroxypropyl methyl cellulose and 51.32% of pure water.
Example 3
The plant essential oil itching relieving gel is characterized by comprising the following components in percentage by mass: 1.3% of menthol, 0.8% of camphor, 3% of glycerol, 0.13% of aloe vera extract, 0.5% of argy wormwood leaf essential oil, 0.015% of chamomile essential oil, 0.014% of camellia seed oil, 0.009% of honeysuckle essential oil, 0.015% of calendula essential oil, 0.007% of rosin essential oil, 35% of ethanol, 0.25% of hydroxypropyl methyl cellulose and 58.96% of pure water.
Example 4
The preparation method of the plant essential oil itching relieving gel in the embodiment 1-3 is characterized by comprising the following steps: dissolving menthol and camphor completely by using ethanol, adding glycerol, aloe barbadensis extract, folium artemisiae argyi essential oil, chamomile essential oil, camellia seed oil, honeysuckle essential oil, calendula essential oil, rosin essential oil and pure water, stirring and dissolving completely at the rotating speed of 500 plus materials of 1000r/min, and then adding hydroxypropyl methyl cellulose while stirring to completely dissolve the mixture to prepare the plant essential oil itching-relieving condensation, which is suitable for people with more than 6 months.
Example 5
The plant essential oil itching relieving gel is characterized by comprising the following components in percentage by mass: 5% of water-soluble peppermint oil, 1% of water-soluble camphor, 5% of water-soluble borneol, 0.1% of glycerol, 0.6% of aloe vera extract, 0.01% of chamomile essential oil, 0.01% of camellia seed oil, 0.01% of honeysuckle essential oil, 0.01% of calendula essential oil, 0.2% of hydroxypropyl methyl cellulose and 87.06% of pure water.
Example 6
The preparation method of the plant essential oil itching relieving gel in the embodiment 5 is characterized by comprising the following steps: adding pure water, adding water-soluble peppermint oil and water-soluble camphor, stirring until the mixture is completely dissolved, adding water-soluble borneol, glycerin, aloe barbadensis extract, folium artemisiae argyi essential oil, chamomile essential oil, camellia oil, honeysuckle essential oil, calendula essential oil, rosin essential oil and pure water, stirring at the rotating speed of 500-plus-one 1000r/min for completely dissolving, then adding hydroxypropyl methyl cellulose while stirring to completely dissolve the mixture, and preparing the plant essential oil itching-relieving condensation gel which is suitable for people more than 3 months.
Claims (5)
1. The plant essential oil itching relieving gel is characterized by comprising the following components in percentage by mass: 0.5-1.3% of menthol, 0.8-1.2% of camphor, 3-6% of glycerol, 0.07-0.13% of aloe vera extract, 0.50-0.70% of argy wormwood leaf essential oil, 0.008-0.015% of chamomile essential oil, 0.007-0.014% of camellia seed oil, 0.009-0.012% of honeysuckle essential oil, 0.008-0.015% of calendula essential oil, 0.007-0.015% of rosin essential oil, 35-40% of ethanol, 0.16-0.25% of hydroxypropyl methyl cellulose and 100% of pure water.
2. The plant essential oil itching-relieving gel according to claim 1, which is characterized by comprising the following components in percentage by mass: 1% of menthol, 1% of camphor, 5% of glycerol, 0.10% of aloe vera extract, 0.60% of folium artemisiae argyi essential oil, 0.01% of chamomile essential oil, 0.01% of camellia seed oil, 0.01% of honeysuckle essential oil, 0.01% of calendula essential oil, 0.01% of rosin essential oil, 40% of ethanol, 0.20% of hydroxypropyl methyl cellulose and 52.05% of pure water.
3. The plant essential oil itching-relieving gel according to claim 1, which is characterized by comprising the following components in percentage by mass: 0.5% of menthol, 1.2% of camphor, 6% of glycerol, 0.07% of aloe vera extract, 0.7% of argy wormwood leaf essential oil, 0.008% of chamomile essential oil, 0.007% of camellia seed oil, 0.012% of honeysuckle essential oil, 0.008% of calendula essential oil, 0.015% of rosin essential oil, 40% of ethanol, 0.16% of hydroxypropyl methyl cellulose and 51.32% of pure water.
4. The plant essential oil itching-relieving gel according to claim 1, which is characterized by comprising the following components in percentage by mass: 1.3% of menthol, 0.8% of camphor, 3% of glycerol, 0.13% of aloe vera extract, 0.5% of argy wormwood leaf essential oil, 0.015% of chamomile essential oil, 0.014% of camellia seed oil, 0.009% of honeysuckle essential oil, 0.015% of calendula essential oil, 0.007% of rosin essential oil, 35% of ethanol, 0.25% of hydroxypropyl methyl cellulose and 58.96% of pure water.
5. The preparation method of the plant essential oil itching relieving gel is characterized by comprising the following steps: dissolving menthol and camphor completely by using ethanol, adding glycerol, aloe barbadensis extract, folium artemisiae argyi essential oil, chamomile essential oil, camellia seed oil, honeysuckle essential oil, calendula essential oil, rosin essential oil and pure water, stirring at the rotating speed of 500 plus materials of 1000r/min for complete dissolution, and then adding hydroxypropyl methyl cellulose while stirring to completely dissolve the mixture to prepare the plant essential oil itching-relieving condensation.
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| CN202110965054.1A CN113576993A (en) | 2021-08-23 | 2021-08-23 | Plant essential oil itching-relieving gel and preparation method thereof |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103463188A (en) * | 2013-09-27 | 2013-12-25 | 江门市新时代外用制剂有限公司 | Relieving itching condensation and preparing method thereof |
| CN104997842A (en) * | 2015-08-21 | 2015-10-28 | 南阳市汇博生物技术有限公司 | Anti-bacteria anti-itch gel and preparation method |
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2021
- 2021-08-23 CN CN202110965054.1A patent/CN113576993A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103463188A (en) * | 2013-09-27 | 2013-12-25 | 江门市新时代外用制剂有限公司 | Relieving itching condensation and preparing method thereof |
| CN104997842A (en) * | 2015-08-21 | 2015-10-28 | 南阳市汇博生物技术有限公司 | Anti-bacteria anti-itch gel and preparation method |
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| 桥口玲子: "《医生推荐的芳香疗法》", 31 May 2014, 吉林科学技术出版社 * |
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