CN113546708B - Full-automatic pretreatment device - Google Patents
Full-automatic pretreatment device Download PDFInfo
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- CN113546708B CN113546708B CN202110845157.4A CN202110845157A CN113546708B CN 113546708 B CN113546708 B CN 113546708B CN 202110845157 A CN202110845157 A CN 202110845157A CN 113546708 B CN113546708 B CN 113546708B
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
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- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
The invention relates to the technical field of vaccine detection, in particular to a full-automatic pretreatment device, which comprises a box body and a workbench fixed on the side wall of the box body, wherein a working cavity is arranged in the box body, a lifting device is arranged on the box body, and the upper end of the lifting device is connected with a sealing cover; the bottom wall of the working cavity is provided with a rotating mechanism, the rotating mechanism is provided with a turntable, and the turntable is provided with a mounting hole for mounting a test tube; the water storage shell is positioned under the water inlet, the lower end of the water storage shell is connected with a flow guide pipe, the water outlet of the flow guide pipe is positioned under the rotary table, the side wall of the working cavity is provided with a water outlet pipe, and the working cavity is provided with an electromagnetic valve at the water outlet pipe; according to the invention, the water storage shell arranged in the working cavity is matched with the flow guide pipe, cold water and hot water are injected from the bottom of the test tube and are gradually raised, so that the temperature change of the whole test tube is ensured to be uniform, and the requirement of treatment work is met.
Description
Technical Field
The invention relates to the technical field of biology, in particular to a full-automatic pretreatment device.
Background
The immune antigen is the main effective component in the bacterin, the inoculation effect and the antigen relevance of bacterin are very big, so the bacterin of production completion need detect the content of antigen wherein, detect the antigen content and need carry out the preliminary treatment of bacterin, extract antigen from bacterin, heat through reagent cooperation bacterin, the cooling, centrifugation, processing such as supersound, whole process is consuming time longer, the manual work carries out holistic processing procedure, need cooperate together to carry out middle transfer control, cause the non-continuity of experiment easily, and influence the actual extraction effect of antigen, influence subsequent detection work, in actual preliminary treatment equipment, it is relatively poor to test tube heating cooling working effect, influence processing work.
Disclosure of Invention
The invention aims to provide a full-automatic pretreatment device, which solves the problem of poor heating and cooling effects of test tubes.
In order to achieve the purpose, the invention provides the following technical scheme:
a full-automatic pretreatment device comprises a box body and a workbench fixed on the side wall of the box body, wherein a working cavity is arranged in the box body, the working cavity penetrates upwards, a lifting device is arranged on the box body, and the upper end of the lifting device is connected with a sealing cover; the bottom wall of the working cavity is provided with a rotating mechanism, the rotating mechanism is provided with a turntable, and the turntable is provided with a mounting hole for mounting a test tube; the water storage shell is positioned under the water inlet, the lower end of the water storage shell is connected with a flow guide pipe, the water outlet of the flow guide pipe is positioned under the rotary table, the side wall of the working cavity is provided with a water outlet pipe, and the working cavity is provided with an electromagnetic valve at the water outlet pipe; the side wall of the working cavity is provided with an ultrasonic generator; the operating panel is arranged on the workbench and electrically connected with the ultrasonic generator, the lifting device, the rotating mechanism and the electromagnetic valve.
Compared with the prior art, the invention has the beneficial effects that: the lifting device is used for controlling the lifting work of the sealing cover, so that the working cavity is sealed and opened, the pretreatment work of the reagent in the test tube is ensured to be in a sealing environment, and the external influence is reduced; the rotating mechanism drives the test tube to rotate through the mounting hole on the turntable, and the ultrasonic generator is matched to ensure that the centrifugal work of test tube treatment is efficiently completed; the temperature rise and the temperature reduction of the test tube treatment are realized by water injection, external water flow is injected through the water inlet hole and the water storage shell, the water storage shell controls the injection range of the water flow and controls the injected water flow to be stored in the water storage shell, thereby realizing that the water level in the water storage shell is higher than the water level of the working chamber, the water storage shell can be matched with a high water level through the guide pipe arranged at the bottom to inject water flow from the bottom of the test tube stably, ensuring the gradual progression from bottom to top of the temperature rise and the temperature reduction of the test tube, ensuring the treatment effect of the temperature rise and the temperature reduction of the test tube, the water outlet of the guide pipe is arranged below the turntable to ensure that the test tube can be fully contacted with the water flow, the water outlet pipe is controlled to be communicated through an electromagnetic valve, after heating is finished, water needs to be drained and ice water needs to be replaced for cooling, the hot water is discharged through the water outlet pipe, and the whole device is controlled through the operation panel arranged on the workbench, so that the device is convenient and fast.
Furthermore, the rotating mechanism comprises a rotating shaft vertically arranged in the working cavity, two rotating discs are arranged on the rotating shaft, and the mounting holes of the upper rotating disc and the lower rotating disc are located on the same vertical straight line.
Further, be equipped with the motor groove in the workstation, the motor inslot is equipped with the motor, the workstation with the terminal surface is equipped with the recess under the box body, be equipped with transmission in the recess, transmission with the pivot is connected, transmission with the motor is connected.
Further, transmission includes first band pulley, the pivot lower extreme stretches into the recess, first band pulley with pivot fixed connection, be connected with the output shaft on the motor, the output shaft lower extreme stretches into the recess, output shaft lower extreme fixedly connected with second band pulley, first band pulley with the second band pulley passes through the conveyer belt transmission and connects.
Further, the vertical rotation of terminal surface installs the connecting axle under the sealed lid, be equipped with the sealing device of sealed test tube on the connecting axle, sealing device includes the connecting rod, the connecting rod with connecting axle fixed connection, the connecting rod is connected with annular pole, annular pole with the connecting axle is the centre of a circle, be equipped with the sponge stopper on the annular pole, sealed lid with during the box body butt, the sponge stopper with mounting hole department is in same vertical straight line.
Further, be equipped with the fixture block on the connecting axle, the fixture block lower extreme is equipped with the cambered surface, the pivot upper end is equipped with the guide way, the guide way lateral wall is equipped with and runs through the draw-in groove of pivot upper end, draw-in groove both sides wall is equipped with the fillet, sealed lid with during the box body butt, the connecting axle stretches into the guide way, the fixture block stretches into the draw-in groove.
Further, elevating gear includes the hydraulic stem, the box body is equipped with the ascending mounting groove of opening, the hydraulic stem with mounting groove sliding connection, the box body in the mounting groove downside is equipped with the fixed slot, fixed mounting has the oil pump in the fixed slot, the oil pump with the hydraulic stem is connected, the oil pump with operating panel electric connection.
Further, the box body is provided with a lifting groove, a lifting rod is arranged in the lifting groove in a sliding mode, and the lifting rod is connected with the sealing cover.
Drawings
Fig. 1 is a schematic overall structure diagram of an embodiment of the present invention.
Fig. 2 is an enlarged structural schematic diagram of a working chamber according to an embodiment of the present invention.
Fig. 3 is a schematic cross-sectional view of a working chamber according to an embodiment of the invention.
Fig. 4 is a schematic structural diagram of a groove structure according to an embodiment of the invention.
Fig. 5 is an enlarged structural view of the ring rod according to an embodiment of the present invention.
Fig. 6 is a schematic structural diagram of a motor slot according to an embodiment of the present invention.
In the figure: 1. a sealing cover; 11. a water inlet hole; 12. a lifting rod; 121. a lifting groove; 13. a hydraulic lever; 131. mounting grooves; 132. an oil pump; 133. fixing grooves; 2. a box body; 21. a working chamber; 22. a drain pipe; 23. a flow guide pipe; 24. an electromagnetic valve; 25. a water storage shell; 26. a groove; 3. a work table; 31. an operation panel; 32. an ultrasonic generator; 33. a motor; 34. a motor slot; 41. mounting holes; 42. a turntable; 43. a rotating shaft; 44. a card slot; 45. a guide groove; 51. an annular rod; 52. a sponge plug; 53. a connecting shaft; 54. a clamping block; 55. a connecting rod; 61. a first pulley; 62. a conveyor belt; 63. an output shaft; 64. a second pulley.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
referring to fig. 1, the invention provides a full-automatic pretreatment device, which comprises a box body 2 and a workbench 3 fixed on the side wall of the box body 2, wherein a working chamber 21 is arranged in the box body 2, the working chamber 21 penetrates upwards, a lifting device is arranged on the box body 2, the upper end of the lifting device is connected with a sealing cover 1, a rubber ring is arranged on the lower end surface of the sealing cover 1, and the sealing cover 1 is in sealing and abutting joint with the box body through the rubber ring; a rotating mechanism is arranged on the bottom wall of the working cavity 21, a rotating disc 42 is arranged on the rotating mechanism, a mounting hole 41 for mounting the test tube is formed in the rotating disc 42, and the rotating mechanism drives the test tube to rotate centrifugally through the mounting hole 41; the sealing cover 1 is provided with a water inlet hole 11, the side wall of the working chamber 21 is provided with a water storage shell 25, the water storage shell 25 is positioned under the water inlet hole 11, hot water and cold water are controlled to enter the working chamber 21 through the water inlet hole 11 and the water storage shell 25, so that heating and cooling work before centrifugal work of the test tube is realized, in the process of heating the test tube, the existing equipment is directly heated and water injection work is carried out from top to bottom, too much heat is easily provided for the bottom of the test tube, reagents above the test tube are insufficiently heated, hot water is controlled through the water storage shell 25, water flow is ensured to flow into the lower end of the water storage shell 25 from the bottom and is connected with the guide pipe 23, the water outlet of the guide pipe 23 is positioned below the rotary table 42, the working chamber 21 is bilaterally symmetrically provided with the water storage shell 25, and the guide pipes 23 are arranged on two sides of the rotary table 42 in a staggered manner, the water flow flows from the water storage shell 25 to the flow guide pipe 23 and then flows into the working cavity 21, the flow guide pipe 23 arranged in a staggered mode guides cold water and hot water which are pressurized to enter the water storage shell 25 to flow, so that a vortex is formed, a plurality of test tubes arranged on a rotary table can be heated or cooled synchronously, a water outlet pipe 22 is arranged on the side wall of the working cavity 21, an electromagnetic valve 24 is arranged at the position, on the water outlet pipe 22, of the working cavity 21, and water drainage and water change are controlled through the electromagnetic valve 24; the side wall of the working cavity 21 is provided with an ultrasonic generator 32, when the test tube rotates centrifugally, the ultrasonic generator 32 is started to work, and the separation work of the antigens in the reagent is carried out in a matching way; an operation panel 31 is arranged on the workbench 3, and the operation panel 31 is electrically connected with the ultrasonic generator 32, the lifting device, the rotating mechanism and the electromagnetic valve 24.
Need carry out centrifugal work when carrying out the preliminary treatment to reagent, the test tube needs to carry out the rotation work, slewing mechanism includes vertical setting in the pivot 43 of working chamber 21, be equipped with two on the pivot 43 carousel 42, from top to bottom the carousel 42 the mounting hole 41 is in same vertical straight line, and the test tube inserts two in the mounting hole 41, and pivot 43 rotates and drives carousel 42 and rotate to make carousel 42 drive the test tube and carry out centrifugal work, be equipped with motor groove 34 in the workstation 3, be equipped with motor 33 in the motor groove 34, the terminal surface is equipped with recess 26 under workstation 3 and the box body 2, be equipped with transmission in the recess 26, transmission with pivot 43 connects, transmission with motor 33 connects, through the work of motor 33 in the workstation, drives through transmission pivot 43 rotates, centrifugal rotation is realized.
In order to ensure the stable operation of the centrifugal operation, the transmission device includes a first belt pulley 61, the lower end of the rotating shaft 43 extends into the groove 26, the first belt pulley 61 is fixedly connected with the rotating shaft 43, the motor 33 is connected with an output shaft 63, the lower end of the output shaft 63 extends into the groove 26, the lower end of the output shaft 63 is fixedly connected with a second belt pulley 64, the first belt pulley 61 is connected with the second belt pulley 63 through a conveying belt 62 in a belt transmission manner, the transmission device is connected with the motor 33 and the rotating shaft 43 through a belt transmission manner, and the transmission is stable.
When the centrifugation rotates, part of water is left in the working cavity 21 to buffer, and the test tube contains reagent, and the rivers sputter appears easily in the centrifugation process, leads to reagent to spill or water gets into the test tube, influences the detection effect, the vertical rotation of terminal surface installs connecting axle 53 under the sealed lid 1, be equipped with the sealing device of sealed test tube on the connecting axle 53, sealing device includes connecting rod 55, connecting rod 55 with connecting axle 53 fixed connection, connecting rod 55 is connected with annular pole 51, annular pole 51 uses the connecting axle 53 as the centre of a circle, be equipped with sponge stopper 53 on the annular pole 51, can drive annular pole 51 through connecting axle 53 and rotate to make sponge stopper 42 follow the test tube and carry out the centrifugation rotation, guarantee going on of work, sealed lid 1 with during the butt of box body 2, sponge stopper 52 with mounting hole 41 is in same vertical straight line, sponge stopper 52 follows sealed lid 1 reciprocates to the butt test tube seals up, and the sponge piece has certain gas permeability, can guarantee to carry out the in-process that heats to the test tube through hot water, and the test tube internal gas pressure is stable.
In the process of placing test tubes after the sealing cover 1 is lifted, the test tubes are in contact with the rotary disc 42, the rotary disc 42 and the annular rod 51 can rotate relatively in the installation process, so that the contact between the sponge plug 52 and the test tubes is influenced, the treatment work cannot be carried out, the connecting shaft 53 is provided with a clamping block 53, the lower end of the clamping block 53 is provided with an arc surface, the upper end of the rotating shaft 43 is provided with a guide groove 45, the side wall of the guide groove 45 is provided with a clamping groove 44 penetrating through the upper end of the rotating shaft 43, two side walls of the clamping groove 44 are provided with round corners, when the sealing cover 1 moves towards the box body 2, the clamping block 53 moves along with the clamping groove 44, when the clamping block 53 and the clamping groove 44 are not on the same vertical plane, the clamping block 53 is in contact with the round corners on two sides of the clamping groove 44, the connecting shaft 53 is rotated through the guide of the round corners and the arc surface of the clamping block, so that the sealing cover 1 is abutted to the box body 2, the connecting shaft 53 extends into the guide groove 45, and the clamping block 53 extends into the clamping groove 44.
The hydraulic stem 13 alone supports the lift of sealed lid 1, the slope of sealed lid 1 appears easily, box body 2 is equipped with lift groove 121, slidable mounting has lifter 12 in lift groove 121, lifter 12 upper end with sealed lid 1 is connected, lifter 12 cooperation the hydraulic stem 13 guarantees sealed lid 1 is in stable condition at the in-process of oscilaltion.
Working state
Firstly, the oil pump 132 is controlled by the control panel 31 to work, the oil pump 132 drives the hydraulic rod 13 to extend, the hydraulic rod 13 drives the sealing cover 1 to move upwards, the lifting rod 12 is matched to support balance work, the sealing cover 1 is prevented from inclining, then the test tubes are placed into the mounting holes 41 of the turntable 42 one by one, the oil pump 132 works, the sealing cover 1 moves downwards, the box body 2 is attached, meanwhile, the sealing cover 1 drives the sponge plug 52 to move, the sponge plug 52 is contacted with the test tubes, the openings of the test tubes are plugged by the sponge plug 52, the test tubes are connected with the water inlet holes 11 through an external pipeline, so that heating water is heated, heating work on the test tubes is realized, hot water flows into the water storage shell 25 from the water inlet holes 11, flows into the working cavity 21 through the guide pipe 23 to be contacted with the test tubes, the test tubes are heated, after the heating work is finished, the operation panel 31 controls the electromagnetic valve 24 to work to drain water, ice water is injected again to cool, after the temperature drops, the operation panel 31 controls the ultrasonic generator 32 and the motor 33 to work, the motor 33 works to drive the output shaft 63 to rotate, the output shaft 63 drives the first belt wheel 61 to rotate through the second belt wheel 64 and the conveying belt 62, the first belt wheel 61 drives the rotating shaft 43 to rotate, the rotating shaft 43 drives the rotating disc 42 to rotate, the rotating disc 42 drives the test tube to rotate through the mounting hole 41 to perform centrifugal work, the ultrasonic generator 32 works to generate ultrasonic waves to cooperate with the test tube to perform centrifugal work, and after the centrifugal work is completed, the sealing cover 1 is opened and the test tube is taken out.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Claims (5)
1. The utility model provides a full-automatic preceding processing apparatus for bacterin antigen content testing, includes box body (2) and workstation (3) that are fixed in box body (2) lateral wall, its characterized in that: a working cavity (21) is arranged in the box body (2), the working cavity (21) penetrates upwards, a lifting device is arranged on the box body (2), and the upper end of the lifting device is connected with a sealing cover (1); a rotating mechanism is arranged on the bottom wall of the working cavity (21), a rotating disc (42) is arranged on the rotating mechanism, and a mounting hole (41) for mounting a test tube is formed in the rotating disc (42); the rotating mechanism comprises a rotating shaft (43) vertically arranged in the working cavity (21), the rotating shaft (43) is provided with two rotating discs (42), the mounting holes (41) of the upper rotating disc (42) and the lower rotating disc (42) are positioned on the same vertical straight line, a connecting shaft (53) is vertically and rotatably arranged on the lower end surface of the sealing cover (1), a sealing device for sealing the test tube is arranged on the connecting shaft (53), the sealing device comprises a connecting rod (55), the connecting rod (55) is fixedly connected with the connecting shaft (53), the connecting rod (55) is connected with an annular rod (51), the annular rod (51) takes the connecting shaft (53) as the center of a circle, a sponge plug (53) is arranged on the annular rod (51), when the sealing cover (1) is abutted against the box body (2), the sponge plug (52) and the mounting hole (41) are in the same vertical straight line; a clamping block (54) is arranged on the connecting shaft (53), an arc surface is arranged at the lower end of the clamping block (54), a guide groove (45) is arranged at the upper end of the rotating shaft (43), a clamping groove (44) penetrating through the upper end of the rotating shaft (43) is arranged on the side wall of the guide groove (45), round corners are arranged on the two side walls of the clamping groove (44), when the sealing cover (1) is abutted against the box body (2), the connecting shaft (53) extends into the guide groove (45), and the clamping block (53) extends into the clamping groove (44); a water inlet hole (11) is formed in the sealing cover (1), a water storage shell (25) is arranged on the side wall of the working cavity (21), the water storage shell (25) is located under the water inlet hole (11), a guide pipe (23) is connected to the lower end of the water storage shell (25), a water outlet of the guide pipe (23) is located under the rotary table (42), a water outlet pipe (22) is arranged on the side wall of the working cavity (21), and an electromagnetic valve (24) is arranged on the position, located on the water outlet pipe (22), of the working cavity (21); an ultrasonic generator (32) is arranged on the side wall of the working cavity (21); an operation panel (31) is arranged on the workbench (3), and the operation panel (31) is electrically connected with the ultrasonic generator (32), the lifting device, the rotating mechanism and the electromagnetic valve (24).
2. The full-automatic pretreatment device for detecting the antigen content of the vaccine according to claim 1, wherein: be equipped with motor groove (34) in workstation (3), be equipped with motor (33) in motor groove (34), workstation (3) with the terminal surface is equipped with recess (26) under box body (2), be equipped with transmission in recess (26), transmission with pivot (43) are connected, transmission with motor (33) are connected.
3. The full-automatic pretreatment device for detecting the antigen content of the vaccine according to claim 2, wherein: the transmission device comprises a first belt wheel (61), the lower end of the rotating shaft (43) extends into the groove (26), the first belt wheel (61) is fixedly connected with the rotating shaft (43), an output shaft (63) is connected to the motor (33), the lower end of the output shaft (63) extends into the groove (26), a second belt wheel (64) is fixedly connected to the lower end of the output shaft (63), and the first belt wheel (61) is in belt transmission connection with the second belt wheel (63) through a conveying belt (62).
4. The full-automatic pretreatment device for detecting the antigen content of the vaccine according to claim 1, wherein: elevating gear includes hydraulic stem (13), box body (2) are equipped with ascending mounting groove (131) of opening, hydraulic stem (13) with mounting groove (131) sliding connection, box body (2) in mounting groove (131) downside is equipped with fixed slot (133), fixed mounting has oil pump (132) in fixed slot (133), oil pump (132) with hydraulic stem (13) lower extreme is connected, sealed lid (1) with hydraulic stem (13) upper end fixed connection, oil pump (132) with operating panel (31) electric connection.
5. The full-automatic pretreatment device for detecting the antigen content of the vaccine according to claim 4, wherein: the box body (2) is further provided with a lifting groove (121), a lifting rod (12) is arranged in the lifting groove (121) in a sliding mode, and the upper end of the lifting rod (12) is connected with the sealing cover (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110845157.4A CN113546708B (en) | 2021-07-26 | 2021-07-26 | Full-automatic pretreatment device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110845157.4A CN113546708B (en) | 2021-07-26 | 2021-07-26 | Full-automatic pretreatment device |
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| CN113546708A CN113546708A (en) | 2021-10-26 |
| CN113546708B true CN113546708B (en) | 2022-08-16 |
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| Publication number | Publication date |
|---|---|
| CN113546708A (en) | 2021-10-26 |
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