CN112170025A - Prevent centrifugal pollution's stem cell rapid centrifuge - Google Patents

Prevent centrifugal pollution's stem cell rapid centrifuge Download PDF

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CN112170025A
CN112170025A CN202011001787.5A CN202011001787A CN112170025A CN 112170025 A CN112170025 A CN 112170025A CN 202011001787 A CN202011001787 A CN 202011001787A CN 112170025 A CN112170025 A CN 112170025A
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stem cell
centrifugal
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鲁乐
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B04B5/0414Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B7/00Elements of centrifuges
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B7/00Elements of centrifuges
    • B04B7/02Casings; Lids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B7/00Elements of centrifuges
    • B04B7/08Rotary bowls
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B17/00Methods preventing fouling
    • B08B17/02Preventing deposition of fouling or of dust
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04Cell isolation or sorting
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16JPISTONS; CYLINDERS; SEALINGS
    • F16J15/00Sealings
    • F16J15/02Sealings between relatively-stationary surfaces

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  • Life Sciences & Earth Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
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  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
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  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Mechanical Engineering (AREA)
  • Centrifugal Separators (AREA)

Abstract

The invention provides a stem cell rapid centrifugal machine capable of preventing centrifugal pollution, belongs to the technical field of cell centrifugal machines, and aims to solve the problem that partial operators easily forget to close a sealing cover on the centrifugal machine and then press a key on an operation panel when the existing centrifugal machine is used, and stem cells pollute the external environment during centrifugation once forgetting to close the sealing cover. When forgetting to close sealed lid before centrifugal work, at first shelter from the mechanism because not obtaining the pulling force, will be located control panel and control the button front side all the time to make the staff can't press control panel and control the button this moment, then remind the staff to close sealed lid, and after closing sealed lid, make control panel on control the button lose the effect of sheltering from, then press it again can, thereby make sealed lid can not forget to close, thereby the phenomenon of polluting the external environment when effectively having avoided the stem cell centrifugation.

Description

Prevent centrifugal pollution's stem cell rapid centrifuge
Technical Field
The invention belongs to the technical field of cell centrifuges, and particularly relates to a stem cell rapid centrifuge capable of preventing centrifugal pollution.
Background
Centrifuges are machines that utilize centrifugal force to separate components of a mixture of liquid and solid particles or liquid and liquid. Centrifuges are used primarily to separate solid particles from a liquid in a suspension, or to separate two liquids in an emulsion that are of different densities and are immiscible with each other (e.g., to separate cream from milk).
For example, application No.: the invention discloses a cell centrifuge, and belongs to the field of cell centrifuges. A cell centrifuge comprises a case, a bracket, a motor, a lifting mechanism, a connecting rod and an extractor; the bracket is fixedly arranged in the case, and a plurality of centrifugal tube slots are arranged on the bracket and used for placing centrifugal tubes; the motor is arranged in the case, an output shaft of the motor is fixedly connected with the bracket, the lifting mechanism is fixedly connected with the upper end surface of the case, and the extractor is fixedly arranged on the connecting rod; just machine case up end is equipped with the through-hole, the through-hole set up in under the extractor, extractor lower extreme accessible the through-hole is visited in the centrifuge tube compare with prior art, and the cell centrifuge of this application passes through screw rod accurate control extractor position, controls the precision height, and it is more convenient to draw.
Based on the above patent search, and the discovery of the apparatus in the prior art, when the stem cells are centrifuged rapidly, a centrifuge is usually used, and the existing centrifuge has the following disadvantages in the actual use process, such as: 1. when the existing centrifugal machine is used, part of operators, especially novice operators, easily forget to close a sealing cover on the centrifugal machine and then press a key on an operation panel, and once the operators forget to close the sealing cover, the phenomenon that stem cells pollute the external environment during centrifugation can be caused; 2. when the existing centrifugal machine is used, the internal centrifugal drum has larger centrifugal force when rotating, and the bottom of the existing centrifugal machine is poor in stability when centrifuging due to the lack of an effective adsorption mechanism, so that the centrifugal effect of stem cells during centrifuging is reduced.
Disclosure of Invention
In order to solve the technical problems, the invention provides a stem cell rapid centrifuge capable of preventing centrifugal pollution, which aims to solve the following defects existing in the actual use process of the existing centrifuge, such as: 1. when the existing centrifugal machine is used, part of operators, especially novice operators, easily forget to close a sealing cover on the centrifugal machine and then press a key on an operation panel, and once the operators forget to close the sealing cover, the phenomenon that stem cells pollute the external environment during centrifugation can be caused; 2. when the existing centrifugal machine is used, the internal centrifugal drum has larger centrifugal force when rotating, and the bottom of the existing centrifugal machine is poor in stability when centrifuging due to the lack of an effective adsorption mechanism, so that the problem of the centrifugation effect of the stem cells during centrifugation is reduced.
The invention relates to a stem cell rapid centrifugal machine capable of preventing centrifugal pollution, which is realized by the following specific technical means:
a stem cell rapid centrifuge capable of preventing centrifugal pollution comprises a shell, wherein a centrifugal motor is mounted on the bottom end face in the shell, and the centrifugal motor is rotatably connected with a driving column through a rotating shaft; the centrifugal drum comprises first elastic buckles, driving blocks, rectangular sliding barrels and rectangular inserting columns, two rectangular sliding barrels are fixedly embedded in the centrifugal drum in a symmetrical mode, three sliding columns are arranged in each rectangular sliding barrel, springs are sleeved outside the three sliding columns in each rectangular sliding barrel, a first elastic buckle is connected to the outside of each three sliding columns in a sliding mode, the upper portions of opposite surfaces of the two first elastic buckles are connected with one driving block through round rods, and two rectangular inserting columns are symmetrically arranged at the bottom end of the centrifugal drum; a circular hole is formed in the top end face of the shell; the upper end surface of the centrifugal motor is provided with a supporting plate, and the upper end surface of the supporting plate is positioned in the shell and is provided with a collecting barrel; a circular hole is formed in the center of the bottom end face of the collecting barrel, and a flow limiting barrel is arranged outside the circular hole on the bottom end face inside the collecting barrel; the diameter of the inner peripheral surface of the current-limiting cylinder in the collecting barrel is larger than that of the outer peripheral surface of the driving column, and four inserting columns which are connected with the four included angles of the supporting plate in a penetrating manner are arranged on the bottom end surface of the collecting barrel in an annular array manner; a sealing mechanism is arranged on the bottom end surface of the inner side of the centrifugal rotary drum; the bottom end face of the shell is provided with an adsorption mechanism, and the upper part of the right side of the adsorption mechanism, which is positioned on the right end face of the shell, is connected with a suction force adjusting mechanism; a shielding mechanism is arranged on the inclined plane of the front side of the shell, and a clamping mechanism is arranged on the front side of the top end face of the shell.
Further, the shell comprises a sealing cover, a limiting plate, limiting blind holes and a control panel, the rear side of the top of the shell is rotatably connected with the sealing cover through a rotating shaft, the middle part of the front side of the sealing cover is provided with the limiting plate, the right side surface of the limiting plate is provided with the two limiting blind holes, the edge of the bottom end surface of the sealing cover is provided with an annular sealing rubber ring, the inclined surface of the shell is provided with the control panel, the front side of the control panel is provided with a control button, and when the sealing cover is in a closed state, the annular sealing rubber ring on the bottom end surface of the;
further, when the centrifugal drum and the driving column are in an installation state, the two rectangular sliding barrels and the two rectangular inserting columns are respectively inserted into the four rectangular through holes in the driving column, and the two first elastic buckles are clamped with the bottom end face of the driving column;
further, the sealing mechanism comprises a sealing plate, a second elastic buckle and a rectangular bayonet, the upper part of the frame-shaped sealing mechanism is rotatably connected with the sealing plate through a rotating shaft, a rectangular through hole is formed in the right side of the bottom end face of the sealing plate, a partition plate is arranged in the middle of the rectangular through hole, a limiting column is further arranged in the rectangular through hole in the sealing plate, springs are sleeved on the outer portions of the limiting column, located on the two sides of the partition plate, two second elastic buckles which are symmetrically distributed are further connected to the outer portions of the limiting column in the rectangular through hole in the sealing plate in a sliding mode, the rectangular bayonet is formed in the middle of the right side of the upper end face of the sealing mechanism, and when the sealing plate is in a closed state;
furthermore, the adsorption mechanism comprises four adsorption discs, connecting pipes and a pressure adjusting pipe, the four adsorption discs are respectively and fixedly connected to four included angles on the bottom end face of the shell, the four connecting pipes are connected among the four adsorption discs and are communicated with the interiors of the four adsorption discs, one connecting pipe on the right side is connected with the pressure adjusting pipe through an air pipe, and the pressure adjusting pipe is funnel-shaped;
furthermore, the shielding mechanism comprises T-shaped supporting pieces, pulleys and pull ropes, the shielding mechanism is of a rectangular plate structure, the left end and the right end of the shielding mechanism are connected with a limiting slide post in a sliding mode, a T-shaped supporting piece fixed on the inclined surface of the shell is arranged outside each limiting slide post, two pulleys are mounted on the inclined end surface of the shielding mechanism, the pull ropes are connected in sliding grooves of the two pulleys in a sliding mode, one end of each pull rope is fixedly connected to the upper portion of the left side of the shielding mechanism, and when the shielding mechanism is in a shielding state, the shielding mechanism is located on the front side of a key on the control panel;
further, the clamping mechanism comprises a sliding bottom plate, a fixed slide block, a fixed clamp block, a pull rod and a driving rod, the clamping mechanism is in inverted L-shaped distribution, the bottom end face of the clamping mechanism is provided with two dovetail slide blocks, the clamping mechanism is connected with the sliding bottom plate fixed on the top end face of the shell in a sliding manner through the two dovetail slide blocks, the left side of the upper end face of the sliding bottom plate is provided with two dovetail slide grooves in a front-back symmetrical manner, the left end and the right end of the upper end face of the sliding bottom plate are respectively and fixedly connected with the fixed clamp block and the fixed slide block, the right end face of the clamping mechanism is provided with two sliding guide rods in a sliding manner, springs are sleeved outside the two sliding guide rods, the right ends of the two sliding guide rods are connected with the pull rod, annular limit blocks are arranged outside the two sliding guide rods, the lower part of the, the left end face of the driving rod is fixedly connected with the other end of the pull rope, and the left side face of the lower part of the clamping mechanism is provided with two inserting columns;
further, suction adjustment mechanism includes adjusting screw, adjusting nut, piston rod and piston piece, suction adjustment mechanism is T font structure, and the inboard rotation of suction adjustment mechanism is connected with adjusting screw, the adjusting screw upper end is equipped with the rotation hand wheel, and the adjusting screw outside has adjusting nut through threaded connection, the connecting block fixedly connected with piston rod is passed through on the adjusting nut right side, and piston rod bottom end face is equipped with the piston piece, works as when suction adjustment mechanism is in the mounted state with adsorption apparatus, the piston piece closely contacts with pressure adjustment intraductal wall.
Compared with the prior art, the invention has the following beneficial effects:
according to the invention, through the matching of the adsorption mechanism and the suction force adjusting mechanism, the centrifuge is placed on a required table top, then the shell is pressed downwards manually, so that the four adsorption discs are adsorbed on the table top, then the adjusting screw rod is rotated, the adjusting nut drives the piston rod to move upwards under the action of the threads, so that the piston block slides upwards in the pressure adjusting pipe, and under the matching of the piston block and the pressure adjusting pipe, negative pressure is formed in the pressure adjusting pipe, so that the adsorption discs are forced to perform further adsorption operation on the table top, and the adsorption force of the adsorption discs during adsorption is further improved, so that the centrifuge has better stability during centrifugation, and the centrifugation effect of stem cells during centrifugation is improved.
According to the invention, through the arrangement of the shielding mechanism, when the sealing cover is forgotten to be closed before centrifugal operation, firstly, the shielding mechanism is always positioned on the front side of the control button on the control panel because tension is not obtained, so that a worker can not press the control button on the control panel at the moment, then the worker is reminded of needing to close the sealing cover, after the sealing cover is closed, the upper end of the pull rope is driven by the driving rod to be pulled rightwards, and then the shielding mechanism is driven to move downwards under the action of the two pulleys, so that the control button on the control panel loses shielding effect, and then the control button is pressed, so that the sealing cover can not be forgotten to be closed, and the phenomenon that the external environment is polluted during the centrifugation of dry cells is effectively avoided.
Drawings
Fig. 1 is a schematic axial view of the present invention.
Fig. 2 is a schematic structural diagram in a split state of the present invention.
Fig. 3 is a schematic view of the collecting barrel and the driving column of the present invention.
FIG. 4 is a schematic axial view of the centrifugal drum and the driving cylinder of the present invention.
FIG. 5 is a schematic structural diagram of the centrifugal drum and the driving column of the present invention after being disassembled.
Fig. 6 is a schematic structural view of the sealing mechanism of the present invention.
Fig. 7 is a schematic structural view of the suction mechanism and the suction force adjusting mechanism of the present invention.
Fig. 8 is a schematic view of the present invention at a part enlarged in fig. 1.
Fig. 9 is a schematic structural view of the clamping mechanism of the present invention after disassembly.
In the drawings, the corresponding relationship between the component names and the reference numbers is as follows:
1. a housing; 101. a sealing cover; 102. a limiting plate; 103. a limiting blind hole; 104. a control panel; 2. a collection barrel; 3. centrifuging the drum; 301. a first elastic buckle; 302. driving the block; 303. a rectangular slide cylinder; 304. rectangular inserting columns; 4. a sealing mechanism; 401. a sealing plate; 402. a second elastic buckle; 403. a rectangular bayonet; 5. an adsorption mechanism; 501. an adsorption tray; 502. a connecting pipe; 503. a pressure regulating tube; 6. a shielding mechanism; 601. a T-shaped support; 602. a pulley; 603. pulling a rope; 7. a clamping mechanism; 701. a sliding bottom plate; 702. fixing the sliding block; 703. fixing the clamping block; 704. a pull rod; 705. driving the rod; 8. a suction force adjusting mechanism; 801. adjusting the screw rod; 802. adjusting the nut; 803. a piston rod; 804. a piston block; 9. a centrifugal motor; 10. a support plate; 11. driving the column.
Detailed Description
The embodiments of the present invention will be described in further detail with reference to the drawings and examples. The following examples are intended to illustrate the invention but are not intended to limit the scope of the invention.
In the description of the present invention, "a plurality" means two or more unless otherwise specified; the terms "upper", "lower", "left", "right", "inner", "outer", "front", "rear", "head", "tail", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are only for convenience in describing and simplifying the description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed in a particular orientation, and be operated, and thus, should not be construed as limiting the invention. Furthermore, the terms "first," "second," "third," and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "connected" and "connected" are to be interpreted broadly, e.g., as being fixed or detachable or integrally connected; can be mechanically or electrically connected; may be directly connected or indirectly connected through an intermediate. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Example (b):
as shown in figures 1 to 9:
the invention provides a stem cell fast centrifuge for preventing centrifugal pollution, which comprises: the centrifugal motor 9 is mounted on the bottom end face inside the shell 1, the shell 1 comprises a sealing cover 101, a limiting plate 102, limiting blind holes 103 and a control panel 104, the sealing cover 101 is rotatably connected to the rear side of the top of the shell 1 through a rotating shaft, the limiting plate 102 is arranged in the middle of the front side of the sealing cover 101, the two limiting blind holes 103 are formed in the right side face of the limiting plate 102, an annular sealing rubber ring is arranged at the edge of the bottom end face of the sealing cover 101, the control panel 104 is arranged at the inclined plane of the shell 1, a control key is arranged on the front side of the control panel 104, and when the sealing cover 101 is in a closed state, the annular sealing rubber ring on; the centrifugal motor 9 is rotationally connected with a driving post 11 through a rotating shaft; the upper end surface of the driving column 11 is provided with four rectangular through holes in an annular array shape, the upper end surface of the driving column 11 is provided with a centrifugal rotary drum 3, the centrifugal rotary drum 3 comprises first elastic buckles 301, driving blocks 302, rectangular sliding barrels 303 and rectangular inserting columns 304, the inner side of the centrifugal rotary drum 3 is fixedly embedded with two rectangular sliding barrels 303 in a symmetrical shape, three sliding columns are arranged in each rectangular sliding barrel 303, springs are sleeved outside the three sliding columns in each rectangular sliding barrel 303, a first elastic buckle 301 is connected outside each three sliding column in a sliding manner, the upper parts of opposite surfaces of the two first elastic buckles 301 are connected with one driving block 302 through round rods, and the bottom end surface of the centrifugal rotary drum 3 is provided with two rectangular inserting columns 304 in a symmetrical shape; a circular hole is formed in the top end face of the shell 1; the upper end surface of the centrifugal motor 9 is provided with a supporting plate 10, and the upper end surface of the supporting plate 10 is positioned in the shell 1 and is provided with a collecting barrel 2; a circular hole is formed in the center of the bottom end face of the collecting barrel 2, and a flow limiting barrel is arranged outside the circular hole on the bottom end face inside the collecting barrel 2; the diameter of the inner peripheral surface of the current-limiting cylinder in the collecting barrel 2 is larger than that of the outer peripheral surface of the driving column 11, and four inserting columns which are in penetrating connection with four included angles of the supporting plate 10 are arranged in an annular array shape at the bottom end of the collecting barrel 2; the bottom end face of the inner side of the centrifugal rotary drum 3 is provided with a sealing mechanism 4, the sealing mechanism 4 comprises a sealing plate 401, a second elastic buckle 402 and a rectangular bayonet 403, the upper part of the frame-shaped sealing mechanism 4 is rotatably connected with the sealing plate 401 through a rotating shaft, the right side of the bottom end face of the sealing plate 401 is provided with a rectangular through hole, the middle part in the rectangular through hole is provided with a partition plate, the rectangular through hole on the sealing plate 401 is also internally provided with a limit column, the outer part of the limit column is positioned at the two sides of the partition plate and is sleeved with a spring, the outer part of the limit column in the rectangular through hole on the sealing plate 401 is also connected with two second elastic buckles 402 which are symmetrically distributed in a sliding manner, the middle part of the right side of the upper end face of the sealing mechanism 4 is provided with the rectangular bayonet 403, when the sealing plate 401 is, thereby the upper part of the centrifugal rotary drum 3 is effectively sealed; the bottom end face of the shell 1 is provided with an adsorption mechanism 5, the adsorption mechanism 5 comprises adsorption discs 501, connecting pipes 502 and pressure adjusting pipes 503, the number of the adsorption discs 501 is four, the four adsorption discs 501 are respectively and fixedly connected to four included angles of the bottom end face of the shell 1, the four connecting pipes 502 are connected among the four adsorption discs 501, the four connecting pipes 502 are communicated with the interiors of the four adsorption discs 501, the right connecting pipe 502 is connected with the pressure adjusting pipe 503 through an air pipe, and the pressure adjusting pipe 503 is funnel-shaped; the upper part of the right side of the adsorption mechanism 5, which is positioned on the right end face of the shell 1, is connected with a suction force adjusting mechanism 8; the shielding mechanism 6 is arranged on the front side inclined plane of the shell 1, the shielding mechanism 6 comprises a T-shaped supporting piece 601, pulleys 602 and pull ropes 603, the shielding mechanism 6 is of a rectangular plate structure, the left end and the right end of the shielding mechanism 6 are both connected with a limiting sliding column in a sliding manner, the outside of each limiting sliding column is provided with the T-shaped supporting piece 601 fixed on the inclined plane of the shell 1, the inclined end face of the shielding mechanism 6 is provided with the two pulleys 602, the sliding grooves of the two pulleys 602 are connected with the pull ropes 603 in a sliding manner, one end of each pull rope 603 is fixedly connected to the upper portion of the left side of the shielding mechanism 6, and when the shielding mechanism 6 is in a shielding state, the shielding mechanism 6 is positioned on the front; the front side of the top end face of the shell 1 is provided with a clamping mechanism 7, the clamping mechanism 7 comprises a sliding bottom plate 701, a fixed sliding block 702, a fixed clamping block 703, a pull rod 704 and a driving rod 705, the clamping mechanism 7 is in inverted L-shaped distribution, the bottom end face of the clamping mechanism 7 is provided with two dovetail sliding blocks, the clamping mechanism 7 is connected with the sliding bottom plate 701 fixed on the top end face of the shell 1 in a sliding way through the two dovetail sliding blocks, the left side of the upper end face of the sliding bottom plate 701 is provided with two dovetail sliding chutes in sliding connection with the two dovetail sliding blocks in a front-back symmetrical way, the left end and the right end of the upper end face of the sliding bottom plate 701 are respectively fixedly connected with the fixed clamping block 703 and the fixed sliding block 702, the right end face of the clamping mechanism 7 is provided with two sliding guide rods in sliding connection with the fixed sliding block 702, springs are sleeved, the lower part of the front end of the clamping mechanism 7 is provided with a driving rod 705 which is distributed in a bent shape, the left end surface of the driving rod 705 is fixedly connected with the other end of the pull rope 603, and the left side surface of the lower part of the clamping mechanism 7 is provided with two insertion columns.
Wherein, when centrifugal rotary drum 3 is in the mounted state with driving post 11, two rectangle slide cartridge 303 and two rectangles are inserted post 304 and are pegged graft respectively in driving four rectangle through-holes on post 11, and two first elastic buckle 301 and the joint of driving 11 bottom faces of post mutually, thereby make centrifugal rotary drum 3 obtain effectual fixed action, and the setting through first elastic buckle 301, it is more convenient when dismantling the change to make centrifugal rotary drum 3, when centrifugal rotary drum 3 more protects, only need to pinch two drive piece 302 to the opposite direction, make two first elastic buckle 301 slide to the opposite direction, thereby time-out centrifugal rotary drum 3 loses the fixed action, then with centrifugal rotary drum 3 upwards slide the dismantlement can, thereby labour saving and time saving when making centrifugal rotary drum 3 dismantle, it is more convenient and fast.
Wherein, the suction adjustment mechanism 8 includes adjusting screw 801, adjusting nut 802, piston rod 803 and piston piece 804, suction adjustment mechanism 8 is the T font structure, and the suction adjustment mechanism 8 inboard rotates and is connected with adjusting screw 801, adjusting screw 801 upper end is equipped with the rotation hand wheel, and there is adjusting nut 802 adjusting screw 801 outside through threaded connection, adjusting nut 802 right side is through connecting block fixedly connected with piston rod 803, and piston rod 803 bottom end face is equipped with piston piece 804, when suction adjustment mechanism 8 is in the mounted state with adsorption mechanism 5, piston piece 804 closely contacts with pressure regulating tube 503 inner wall, through the setting of suction adjustment mechanism 8, make the adsorption affinity of adsorbing dish 501 obtain nimble regulation.
When in use: the centrifugal machine is placed on a needed table board, the shell 1 is pressed downwards manually, the four adsorption discs 501 are adsorbed on the table board, the adjusting screw 801 is rotated, the adjusting nut 802 drives the piston rod 803 to move upwards under the action of threads, so that the piston block 804 slides upwards in the pressure adjusting pipe 503, negative pressure is formed in the pressure adjusting pipe 503 under the matching of the piston block 804 and the pressure adjusting pipe 503, the adsorption discs 501 are forced to perform further adsorption operation on the table board, the adsorption force of the adsorption discs 501 during adsorption is further improved, and the centrifugal machine has good stability during centrifugation; then, the stem cell test tubes are uniformly inserted into the mounting holes on the centrifugal rotary drum 3, and then the centrifugal motor 9 is started through the control panel 104 to carry out centrifugal work after the sealing cover 101 is closed, so that the centrifugal effect of stem cell centrifugation is improved;
when forgetting to close the sealing cover 101 before centrifugal operation, firstly, the shielding mechanism 6 is always located on the control panel 104 at the front side of the control button due to no pulling force obtained, so that the operator cannot press the control button on the control panel 104 at this time, then is reminded of needing to close the sealing cover 101, and when closing the sealing cover 101, the clamping mechanism 7 is made to slide rightwards on the upper part of the sliding bottom plate 701 by manually pulling the pull rod 704, then the sealing cover 101 is closed, so that the limit plate 102 is located between the clamping mechanism 7 and the fixed clamping block 703, then the pull rod 704 is loosened, the clamping mechanism 7 is made to move leftwards under the action of the spring, then the limit plate 102 is clamped by matching with the fixed clamping block 703, and two inserting columns on the left side of the lower part of the clamping mechanism 7 are inserted into the two limit blind holes 103, so that the closed sealing cover 101 can obtain effective limit, slide right at fixture 7 simultaneously, drive stay cord 603 upper end through drive rod 705 and stimulate right, then under two pulley 602 effects to the messenger shelters from mechanism 6 and offers downstream, thereby makes control button on control panel 104 lose the shielding effect, then press it can again, thereby make sealed lid 101 can not forget to close, thereby pollution external environment's phenomenon when effectively having avoided the stem cell centrifugation.
The embodiments of the present invention have been presented for purposes of illustration and description, and are not intended to be exhaustive or limited to the invention in the form disclosed. Many modifications and variations will be apparent to those of ordinary skill in the art. The embodiment was chosen and described in order to best explain the principles of the invention and the practical application, and to enable others of ordinary skill in the art to understand the invention for various embodiments with various modifications as are suited to the particular use contemplated.

Claims (8)

1. The utility model provides a prevent centrifugal pollution's stem cell rapid centrifuge which characterized in that: the centrifugal machine comprises a shell (1), wherein a centrifugal motor (9) is arranged on the bottom end face in the shell (1), and the centrifugal motor (9) is rotatably connected with a driving column (11) through a rotating shaft; the centrifugal drum is characterized in that four rectangular through holes are formed in the upper end face of the driving column (11) in an annular array manner, a centrifugal drum (3) is installed on the upper end face of the driving column (11), the centrifugal drum (3) comprises first elastic buckles (301), driving blocks (302), rectangular sliding cylinders (303) and rectangular inserting columns (304), two rectangular sliding cylinders (303) are fixedly embedded in the centrifugal drum (3) in a symmetrical manner, three sliding columns are arranged in each rectangular sliding cylinder (303), springs are sleeved outside the three sliding columns in each rectangular sliding cylinder (303), a first elastic buckle (301) is connected to the outside of each three sliding columns in a sliding manner, the upper parts of opposite faces of the two first elastic buckles (301) are connected with one driving block (302) through round rods, and two rectangular inserting columns (304) are symmetrically arranged at the bottom end face of the centrifugal drum (3); a round hole is formed in the top end face of the shell (1); a supporting plate (10) is arranged on the upper end face of the centrifugal motor (9), and a collecting barrel (2) is arranged inside the shell (1) on the upper end face of the supporting plate (10); a circular hole is formed in the center of the bottom end face of the collecting barrel (2), and a flow limiting barrel is arranged outside the circular hole on the bottom end face inside the collecting barrel (2); the diameter of the inner peripheral surface of the current-limiting cylinder in the collecting barrel (2) is larger than that of the outer peripheral surface of the driving column (11), and four inserting columns which are in penetrating connection with four included angles of the supporting plate (10) are arranged in an annular array shape at the bottom end surface of the collecting barrel (2); a sealing mechanism (4) is arranged on the bottom end surface of the inner side of the centrifugal drum (3); an adsorption mechanism (5) is arranged on the bottom end face of the shell (1), and a suction force adjusting mechanism (8) is connected to the upper portion of the right side of the adsorption mechanism (5) and is located on the right end face of the shell (1); a shielding mechanism (6) is arranged on the inclined plane of the front side of the shell (1), and a clamping mechanism (7) is arranged on the front side of the top end face of the shell (1).
2. The stem cell rapid centrifuge of claim 1, wherein the stem cell rapid centrifuge comprises: casing (1) is including sealed lid (101), limiting plate (102), spacing blind hole (103) and control panel (104), casing (1) top rear side rotates through the pivot and is connected with sealed lid (101), and sealed lid (101) front side middle part is equipped with limiting plate (102), two spacing blind hole (103) have been seted up to limiting plate (102) right flank, sealed lid (101) bottom face edge is equipped with annular sealing rubber ring, casing (1) inclined plane department is equipped with control panel (104), and control panel (104) front side is equipped with control button, works as when sealed lid (101) is in the closed condition, sealed lid (101) bottom face annular sealing rubber ring closely contacts with collecting vessel (2) up end.
3. The stem cell rapid centrifuge of claim 1, wherein the stem cell rapid centrifuge comprises: when the centrifugal rotary drum (3) and the driving column (11) are in an installation state, the two rectangular sliding barrels (303) and the two rectangular inserting columns (304) are respectively inserted into the four rectangular through holes in the driving column (11), and the two first elastic buckles (301) are clamped with the bottom end face of the driving column (11).
4. The stem cell rapid centrifuge of claim 1, wherein the stem cell rapid centrifuge comprises: the sealing mechanism (4) comprises a sealing plate (401), a second elastic buckle (402) and a rectangular bayonet (403), the sealing mechanism (4) is a frame-shaped sealing mechanism (4), the upper part of the sealing mechanism (4) is rotationally connected with a sealing plate (401) through a rotating shaft, the right side of the bottom end surface of the sealing plate (401) is provided with a rectangular through hole, a baffle plate is arranged in the middle of the rectangular through hole, a limit column is also arranged in the rectangular through hole on the sealing plate (401), springs are sleeved on the outer portions of the limiting columns at the two sides of the partition plate, two second elastic buckles (402) which are symmetrically distributed are connected to the outer portions of the limiting columns in the rectangular through holes on the sealing plate (401) in a sliding mode, a rectangular bayonet (403) is arranged in the middle of the right side of the upper end surface of the sealing mechanism (4), when the sealing plate (401) is in a closed state, the two second elastic buckles (402) are buckled with the rectangular bayonets (403).
5. The stem cell rapid centrifuge of claim 1, wherein the stem cell rapid centrifuge comprises: adsorption apparatus constructs (5) including adsorbing dish (501), connecting pipe (502) and pressure adjustment pipe (503), the quantity of adsorbing dish (501) is four, and four adsorb dish (501) respectively fixed connection in four contained angles departments of casing (1) bottom face, four be connected with four connecting pipes (502) between adsorbing dish (501), and four connecting pipes (502) all communicate with each other with four inside of adsorbing dish (501), and a connecting pipe (502) in right side is connected with pressure adjustment pipe (503) through the trachea, and its shape of pressure adjustment pipe (503) sets up to leaking hopper-shaped.
6. The stem cell rapid centrifuge of claim 1, wherein the stem cell rapid centrifuge comprises: shelter from mechanism (6) and include T type support piece (601), pulley (602) and stay cord (603), shelter from that mechanism (6) is rectangular plate block structure, and shelter from mechanism (6) and control the equal sliding connection in both ends and have a spacing traveller, every spacing traveller outside all is equipped with one T type support piece (601) of fixing on casing (1) inclined plane, shelter from and install two pulley (602) on the mechanism (6) inclined end face, and sliding connection has a stay cord (603) in two pulley (602) spouts, stay cord (603) one end fixed connection is on sheltering from mechanism (6) left side upper portion, works as shelter from when mechanism (6) is in the state of sheltering from, shelter from that mechanism (6) is located control panel (104) and goes up the button front side.
7. The stem cell rapid centrifuge of claim 1, wherein the stem cell rapid centrifuge comprises: the clamping mechanism (7) comprises a sliding bottom plate (701), a fixed sliding block (702), a fixed clamping block (703), a pull rod (704) and a driving rod (705), the clamping mechanism (7) is distributed in an inverted L shape, two dovetail sliding blocks are arranged on the bottom end face of the clamping mechanism (7), the clamping mechanism (7) is connected with the sliding bottom plate (701) fixed on the top end face of the shell (1) in a sliding mode through the two dovetail sliding blocks, two dovetail sliding chutes in sliding connection with the two dovetail sliding blocks are symmetrically formed in the front and back mode in the left side of the upper end face of the sliding bottom plate (701), the fixed clamping block (703) and the fixed sliding block (702) are fixedly connected to the left end and the right end of the upper end face of the sliding bottom plate (701) respectively, two sliding guide rods in sliding connection with the fixed sliding blocks (702) are arranged on the right end face of the clamping mechanism (7), springs are sleeved outside the two sliding guide rods, and the right ends of the outer parts of the two sliding guide rods are respectively provided with an annular limiting block, the lower part of the front end of the clamping mechanism (7) is provided with a driving rod (705) which is distributed in a bent shape, the left end face of the driving rod (705) is fixedly connected with the other end of the pull rope (603), and the left side surface of the lower part of the clamping mechanism (7) is provided with two inserting columns.
8. The stem cell rapid centrifuge of claim 1, wherein the stem cell rapid centrifuge comprises: suction adjustment mechanism (8) are including adjusting screw (801), adjusting nut (802), piston rod (803) and piston piece (804), suction adjustment mechanism (8) are T font structure, and suction adjustment mechanism (8) inboard rotation is connected with adjusting screw (801), adjusting screw (801) upper end is equipped with the rotation hand wheel, and adjusting screw (801) outside has adjusting nut (802) through threaded connection, connecting block fixedly connected with piston rod (803) is passed through on adjusting nut (802) right side, and piston rod (803) bottom face is equipped with piston piece (804), works as when suction adjustment mechanism (8) are in the mounted state with adsorption apparatus (5), piston piece (804) and pressure regulation pipe (503) inner wall in close contact with.
CN202011001787.5A 2020-09-22 2020-09-22 Prevent centrifugal pollution's stem cell rapid centrifuge Withdrawn CN112170025A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112676049A (en) * 2021-01-29 2021-04-20 新乡医学院三全学院 Centrifugal device for experiment of producing microglia by inducing pluripotent stem cells
CN113546708A (en) * 2021-07-26 2021-10-26 杭州都林生物科技有限公司 Full-automatic pretreatment device
CN113600114A (en) * 2021-08-09 2021-11-05 哈尔滨工业大学 Be used for organic chemical reaction viewing device
CN114178057A (en) * 2021-12-08 2022-03-15 广州贝特生物科技有限公司 Stable high-speed refrigerated centrifuge and use method thereof
CN114260105A (en) * 2021-12-08 2022-04-01 浙江大学 Exosome extraction element
CN117259028A (en) * 2023-09-18 2023-12-22 深圳博瀚医学检验实验室 Equipment for concentrating stem cell exosomes

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112676049A (en) * 2021-01-29 2021-04-20 新乡医学院三全学院 Centrifugal device for experiment of producing microglia by inducing pluripotent stem cells
CN113546708A (en) * 2021-07-26 2021-10-26 杭州都林生物科技有限公司 Full-automatic pretreatment device
CN113546708B (en) * 2021-07-26 2022-08-16 杭州都林生物科技有限公司 Full-automatic pretreatment device
CN113600114A (en) * 2021-08-09 2021-11-05 哈尔滨工业大学 Be used for organic chemical reaction viewing device
CN114178057A (en) * 2021-12-08 2022-03-15 广州贝特生物科技有限公司 Stable high-speed refrigerated centrifuge and use method thereof
CN114260105A (en) * 2021-12-08 2022-04-01 浙江大学 Exosome extraction element
CN114260105B (en) * 2021-12-08 2022-12-20 浙江大学 Exosome extraction element
CN114178057B (en) * 2021-12-08 2023-03-31 广州贝特生物科技有限公司 Stable high-speed refrigerated centrifuge and use method thereof
CN117259028A (en) * 2023-09-18 2023-12-22 深圳博瀚医学检验实验室 Equipment for concentrating stem cell exosomes
CN117259028B (en) * 2023-09-18 2024-06-11 深圳博瀚医学检验实验室 Equipment for concentrating stem cell exosomes

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Application publication date: 20210105