CN113521028A - 一种石斛粉纳米胶囊的制备方法 - Google Patents
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Abstract
本发明提供了一种石斛粉纳米胶囊的制备方法,石斛粉纳米微胶囊由以下成分按照重量百分比组成:石斛粉为7wt%‑19wt%、大豆磷脂为11wt%‑14wt%、阿拉伯胶15wt%‑21wt%、蜂蜡为8wt%‑12wt%、聚乙烯醇为2wt%‑5wt%、余量为环糊精;S1、取芯材石斛粉和大豆磷脂,称取石斛粉、大豆磷脂,将石斛粉与大豆磷脂加热下溶解后用乳化搅拌机进行乳化;S2、取阿拉伯胶、蜂蜡、聚乙烯醇,环糊精,将原料溶于水中;S3、将芯材与壁材水溶液混合,混合后用均质机进行均质;S4、均质后将混合的水溶液进行喷雾干燥,收集得到石斛粉纳米微胶囊。本发明优点在于,制备方法制备得到了石斛粉的微胶囊,制备方法中使用的芯材和壁材均为易于制备的原料,制备得到的石斛粉纳米微胶囊包埋率达到了86.3%至91.2%。
Description
技术领域
本发明涉及微胶囊技术领域,尤其涉及一种石斛粉纳米胶囊的制备方法。
背景技术
石斛粉是用干石斛磨成的粉,石斛粉作为石斛加工的一种形式,拓宽了石斛的用途,但是由于其固定的物理性质,如粘性和分散性限制了应用,如果将其加工成速溶的石斛粉将对于使用者带来极大的方便,从而拉动石斛产业的发展。
微胶囊指将某一目的物用各种天然的或合成的高分子化合物连续薄膜完全包覆起来,而对目的物的原有化学性质丝毫无损,然后逐渐的通过某些外部刺激或缓释作用使目的物的功能再次在外部呈现出来,或者依靠囊壁的屏蔽作用保护芯材的作用;
目前将石斛粉制备成为微胶囊的方法包埋率低下,扩大石斛粉的应用领域需要进行解决。
发明内容
本发明针对现有技术的不足,提供了一种石斛粉纳米胶囊的制备方法。
本发明通过以下技术手段实现解决上述技术问题的:
一种石斛粉纳米胶囊的制备方法,石斛粉纳米微胶囊由以下成分按照重量百分比组成:石斛粉为7wt%-19wt%、大豆磷脂为11wt%-14wt%、阿拉伯胶15wt%-21wt%、蜂蜡为8wt%-12wt%、聚乙烯醇为2wt%-5wt%、余量为环糊精;
石斛粉纳米微胶囊制备方法如下:
S1、取芯材石斛粉和大豆磷脂,称取石斛粉、大豆磷脂,将石斛粉与大豆磷脂加热下溶解后用乳化搅拌机进行乳化;
S2、取阿拉伯胶、蜂蜡、聚乙烯醇,环糊精,将原料溶于水中;
S3、将芯材与壁材水溶液混合,混合后用均质机进行均质;
S4、均质后将混合的水溶液进行喷雾干燥,收集得到石斛粉纳米微胶囊。
优选的,所述S1中加热溶解温度为65度。
优选的,所述S3中均质压力为60mpa-100mpa,均质温度为45 ℃,均质时间为30-60min。
优选的,所述S4中喷雾干燥进风温度为130度,出风温度为90 度。
优选的,所述环糊精为beta-环糊精。
本发明的优点在于:制备方法制备得到了石斛粉的微胶囊,制备方法中使用的芯材和壁材均为易于制备的原料,制备得到的石斛粉纳米微胶囊包埋率达到了86.3%至91.2%。
具体实施方式
为使本发明实施例的目的、技术方案和优点更加清楚,下面将结合本发明实施例,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。
实施例1
S1、取芯材石斛粉和大豆磷脂,称取石斛粉为10g、大豆磷脂为 13g,将石斛粉与大豆磷脂加热至65度下溶解后用乳化搅拌机进行乳化,乳化后芯材备用;
S2、取阿拉伯胶为17g、蜂蜡为9g,聚乙烯醇为4g,环糊精为 45g,将上述原料溶于270g水中,混合均匀后与壁材水溶液;
S3、将芯材与壁材水溶液混合,混合后用均质机进行均质,均质压力为80mpa,均质温度为45度,均质时间为60min;
S4、均质后将混合的水溶液进行喷雾干燥,喷雾干燥参数如下:进风温度为130度,出风温度为90度,收集得到石斛粉纳米微胶囊。。
实施例2
S1、取芯材石斛粉和大豆磷脂,称取石斛粉为8g、大豆磷脂为 15g,将丙氨酸与大豆磷脂加热至65度下溶解后用乳化搅拌机进行乳化,乳化后芯材备用;
S2、取阿拉伯胶为15g、蜂蜡为13g,聚乙烯醇为2g,环糊精为 49g,将上述原料溶于320g水中,混合均匀后为壁材水溶液;
S3、将芯材与壁材水溶液混合,混合后用均质机进行均质,均质压力为90mpa,均质温度为45度,均质时间为30min;
S4、均质后将混合的水溶液进行喷雾干燥,喷雾干燥参数如下:进风温度为130度,出风温度为90度,收集得到石斛粉纳米微胶囊。。
实施例3
S1、取芯材石斛粉和大豆磷脂,称取丙氨酸为19g、大豆磷脂为 11g,将丙氨酸与大豆磷脂加热至65度下溶解后用乳化搅拌机进行乳化,乳化后芯材备用;
S2、取阿拉伯胶为21g、蜂蜡为8g,聚乙烯醇为5g,环糊精为 36g,将上述原料溶于200g水中,混合均匀后为壁材水溶液;
S3、将芯材与壁材水溶液混合,混合后用均质机进行均质,均质压力为70mpa,均质温度为45度,均质时间为60min;
S4、均质后将混合的水溶液进行喷雾干燥,喷雾干燥参数如下:进风温度为130度,出风温度为90度,收集得到石斛粉纳米微胶囊。
实施例1至3的石斛粉微纳米胶囊的包埋率如下:
实施例1 | 实施例2 | 实施例3 | |
包埋率 | 91.2% | 86.3% | 89.9% |
实施例1至3的石斛粉纳米微胶囊的包埋率都较高,同时其粒径也较小,形态也较为统一,具有良好的包埋效果,有效的扩大了石斛粉的应用途径。
需要说明的是,在本文中,如若存在第一和第二等之类的关系术语仅仅用来将一个实体或者操作与另一个实体或操作区分开来,而不一定要求或者暗示这些实体或操作之间存在任何这种实际的关系或者顺序。而且,术语“包括”、“包含”或者其任何其他变体意在涵盖非排他性的包含,从而使得包括一系列要素的过程、方法、物品或者设备不仅包括那些要素,而且还包括没有明确列出的其他要素,或者是还包括为这种过程、方法、物品或者设备所固有的要素。在没有更多限制的情况下,由语句“包括一个……”限定的要素,并不排除在包括所述要素的过程、方法、物品或者设备中还存在另外的相同要素。
以上实施例仅用以说明本发明的技术方案,而非对其限制;尽管参照前述实施例对本发明进行了详细的说明,本领域的普通技术人员应当理解:其依然可以对前述各实施例所记载的技术方案进行修改,或者对其中部分技术特征进行等同替换;而这些修改或者替换,并不使相应技术方案的本质脱离本发明各实施例技术方案的精神和范围。
Claims (5)
1.一种石斛粉纳米胶囊的制备方法,其特征在于:石斛粉纳米微胶囊由以下成分按照重量百分比组成:石斛粉为7wt%-19wt%、大豆磷脂为11wt%-14wt%、阿拉伯胶15wt%-21wt%、蜂蜡为8wt%-12wt%、聚乙烯醇为2wt%-5wt%、余量为环糊精;
石斛粉纳米微胶囊制备方法如下:
S1、取芯材石斛粉和大豆磷脂,称取石斛粉、大豆磷脂,将石斛粉与大豆磷脂加热下溶解后用乳化搅拌机进行乳化;
S2、取阿拉伯胶、蜂蜡、聚乙烯醇,环糊精,将原料溶于水中;
S3、将芯材与壁材水溶液混合,混合后用均质机进行均质;
S4、均质后将混合的水溶液进行喷雾干燥,收集得到石斛粉纳米微胶囊。
2.根据权利要求1所述的一种石斛粉纳米胶囊的制备方法,其特征在于:所述S1中加热溶解温度为65度。
3.根据权利要求1所述的一种石斛粉纳米胶囊的制备方法,其特征在于:所述S3中均质压力为60mpa-100mpa,均质温度为45℃,均质时间为30-60min。
4.根据权利要求1所述的一种石斛粉纳米胶囊的制备方法,其特征在于:所述S4中喷雾干燥进风温度为130度,出风温度为90度。
5.根据权利要求1所述的一种石斛粉纳米胶囊的制备方法,其特征在于:所述环糊精为beta-环糊精。
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