CN113509522A - A Chinese medicinal health product for delaying aging, and its preparation method - Google Patents

A Chinese medicinal health product for delaying aging, and its preparation method Download PDF

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Publication number
CN113509522A
CN113509522A CN202010282310.2A CN202010282310A CN113509522A CN 113509522 A CN113509522 A CN 113509522A CN 202010282310 A CN202010282310 A CN 202010282310A CN 113509522 A CN113509522 A CN 113509522A
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traditional chinese
health product
medicine
raw materials
preparation
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朱明帅
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Beijing Yongkang Gucao Traditional Chinese Medicine Technology Co ltd
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Beijing Yongkang Gucao Traditional Chinese Medicine Technology Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/82—Theaceae (Tea family), e.g. camellia
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
    • A23F3/00—Tea; Tea substitutes; Preparations thereof
    • A23F3/06—Treating tea before extraction; Preparations produced thereby
    • A23F3/14—Tea preparations, e.g. using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
    • A23F3/00—Tea; Tea substitutes; Preparations thereof
    • A23F3/16—Tea extraction; Tea extracts; Treating tea extract; Making instant tea
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
    • A23F3/00—Tea; Tea substitutes; Preparations thereof
    • A23F3/16—Tea extraction; Tea extracts; Treating tea extract; Making instant tea
    • A23F3/30—Further treatment of dried tea extract; Preparations produced thereby, e.g. instant tea
    • A23F3/32—Agglomerating, flaking or tabletting or granulating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/75—Rutaceae (Rue family)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
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    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract

The invention discloses a traditional Chinese medicine health product for delaying senility and a preparation method thereof, wherein the traditional Chinese medicine health product for delaying senility is prepared from the following raw materials: 5-10 g of raw green tea, 5-10 g of liquorice, 5-10 g of medlar, 5-10 g of cassia seed, 5-10 g of tuckahoe, 5-10 g of raw hawthorn, 5-10 g of mulberry, 10-12 g of daidaidaidai flower, 5-12 g of kudzuvine root, 5-10 g of giant knotweed rhizome, 5-10 g of lucid ganoderma, 5-10 g of rhizoma polygonati, 5-10 g of chrysanthemum and 10-15 g of Chinese date. The traditional Chinese medicine health product for delaying senility can be prepared into three dosage forms: (1) making into medicated tea; (2) making into granule; (3) making into oral liquid. Compared with the prior art, the invention has the advantages that: the invention has obvious health care and aging delaying effects.

Description

A Chinese medicinal health product for delaying aging, and its preparation method
Technical Field
The invention relates to a traditional Chinese medicine, in particular to a traditional Chinese medicine health product for delaying senility and a preparation method thereof.
Background
At present, the health care products for delaying senility on the market have the conditions of insufficient eating and excessive eating, and the effect is not good enough. Therefore, the research and development of a traditional Chinese medicine health product for delaying senescence and a preparation method thereof become problems to be urgently solved by technical personnel in the field.
Disclosure of Invention
The invention provides a traditional Chinese medicine health product for delaying senility and a preparation method thereof in order to solve the defects.
The above object of the present invention is achieved by the following technical means: a traditional Chinese medicine health product for delaying senility is composed of the following raw materials: 5-10 g of raw green tea, 5-10 g of liquorice, 5-10 g of medlar, 5-10 g of cassia seed, 5-10 g of tuckahoe, 5-10 g of raw hawthorn, 5-10 g of mulberry, 10-12 g of daidaidaidai flower, 5-12 g of kudzuvine root, 5-10 g of giant knotweed rhizome, 5-10 g of lucid ganoderma, 5-10 g of rhizoma polygonati, 5-10 g of chrysanthemum and 10-15 g of Chinese date.
Preferably, the traditional Chinese medicine for delaying senescence is prepared from the following raw materials: 6-9 g of raw green tea, 6-9 g of liquorice, 6-9 g of wolfberry, 6-9 g of cassia seed, 6-9 g of poria cocos, 6-9 g of raw hawthorn, 6-9 g of mulberry, 11-12 g of daidaidaidai flower, 7-10 g of kudzu root, 6-9 g of giant knotweed rhizome, 6-9 g of lucid ganoderma, 6-9 g of rhizoma polygonati, 6-9 g of chrysanthemum and 11-14 g of Chinese date.
Preferably, the traditional Chinese medicine for delaying senescence is prepared from the following raw materials: 8 g of raw green tea, 8 g of liquorice, 8 g of medlar, 8 g of cassia seed, 8 g of tuckahoe, 8 g of raw hawthorn, 8 g of mulberry, 11 g of daidaidai flower, 9 g of kudzuvine root, 8 g of giant knotweed, 8 g of lucid ganoderma, 8 g of rhizoma polygonati, 8 g of chrysanthemum and 13 g of Chinese date.
Modern pharmacological research shows that the main chemical components of the tuckahoe are polysaccharide and triterpenes, and the tuckahoe has the effects of inhibiting tumors, resisting inflammation, regulating immunity and the like. The Poria water extract can be used for delaying aging by increasing hydroxyproline content in skin.
The preparation method of the traditional Chinese medicine health product for delaying senility comprises the preparation methods of three formulations:
(1) preparing a tea preparation: removing impurities from the medicines, oven drying, pulverizing, mixing, sieving, packaging into sterilized filter tea bag, and sealing; the tea bag is provided with a traction and lifting short line.
(2) Preparing into granules: according to the formula amount, removing impurities from the Chinese herbal medicine raw materials, mixing and crushing the raw materials into coarse powder (5-10 meshes), putting the coarse powder into an extraction tank, adding water which is 3 times of the weight of the raw materials, boiling the coarse powder for one hour with slow fire, filtering out liquid medicine, then adding water which is three times of the weight of the Chinese herbal medicine, boiling the fine powder for another half hour with slow fire, filtering out liquid medicine, combining the front liquid medicine and the back liquid medicine, cooling, adding ethanol which is 1-2 times of the weight of the Chinese herbal medicine and has the concentration of 90%, fully mixing the mixture, standing the mixture and precipitating the mixture; collecting supernatant after 24 hr, washing precipitate with small amount of 50-60% ethanol, mixing the washing solution with the filtrate, recovering ethanol under reduced pressure, concentrating until the crude drug content is 25%, cooling, standing for 15 hr to precipitate completely, filtering, evaporating the filtrate at low temperature to obtain soft extract with specific gravity hot side (80-90 deg.C) of 1.30-1.35; grinding sucrose crystals into fine powder, sieving with a 80-100 mesh sieve for later use, taking commercial dextrin for later use, and uniformly stirring the Chinese herbal medicine thick paste, the sugar powder and the dextrin according to the weight ratio of 1:3:1 to obtain a finished product.
(3) Preparing oral liquid: preparing Chinese herbal medicine soft extract according to the same process as that for preparing the medicinal granules, diluting the soft extract with appropriate amount of distilled water, filtering, adding sucrose and potassium sorbate to obtain oral liquid product, wherein the crude drug content of the diluted solution is 30%.
Compared with the prior art, the invention has the advantages that: the invention has obvious health care and aging delaying effects.
Detailed Description
The present invention will be described in more detail with reference to examples.
Example 1: a traditional Chinese medicine health product for delaying senility is composed of the following raw materials: 5 g of raw green tea, 5 g of liquorice, 5 g of medlar, 5 g of cassia seed, 5 g of tuckahoe, 5 g of raw hawthorn, 5 g of mulberry, 10 g of daidaidai flower, 5 g of kudzuvine root, 5 g of giant knotweed, 5 g of lucid ganoderma, 5 g of rhizoma polygonati, 5 g of chrysanthemum and 10 g of Chinese date.
The invention relates to a method for preparing a traditional Chinese medicine health product made into a tea preparation for delaying senility, which comprises the following steps: removing impurities from the medicines, oven drying, pulverizing, mixing, sieving, packaging into sterilized filter tea bag, and sealing; the tea bag is provided with a traction and lifting short line.
Example 2: a traditional Chinese medicine health product for delaying senility is composed of the following raw materials: 8 g of raw green tea, 8 g of liquorice, 8 g of medlar, 8 g of cassia seed, 8 g of tuckahoe, 8 g of raw hawthorn, 8 g of mulberry, 11 g of daidaidai flower, 9 g of kudzuvine root, 8 g of giant knotweed, 8 g of lucid ganoderma, 8 g of rhizoma polygonati, 8 g of chrysanthemum and 13 g of Chinese date.
The invention relates to a preparation method of a Chinese medicinal health product for delaying senility, which is prepared into medicinal granules, and the preparation method comprises the following steps: according to the formula amount, removing impurities from the Chinese herbal medicine raw materials, mixing and crushing the raw materials into coarse powder (5-10 meshes), putting the coarse powder into an extraction tank, adding water which is 3 times of the weight of the raw materials, boiling the coarse powder for one hour with slow fire, filtering out liquid medicine, then adding water which is three times of the weight of the Chinese herbal medicine, boiling the fine powder for another half hour with slow fire, filtering out liquid medicine, combining the front liquid medicine and the back liquid medicine, cooling, adding ethanol which is 1-2 times of the weight of the Chinese herbal medicine and has the concentration of 90%, fully mixing the mixture, standing the mixture and precipitating the mixture; collecting supernatant after 24 hr, washing precipitate with small amount of 50-60% ethanol, mixing the washing solution with the filtrate, recovering ethanol under reduced pressure, concentrating until the crude drug content is 25%, cooling, standing for 15 hr to precipitate completely, filtering, evaporating the filtrate at low temperature to obtain soft extract with specific gravity hot side (80-90 deg.C) of 1.30-1.35; grinding sucrose crystals into fine powder, sieving with a 80-100 mesh sieve for later use, taking commercial dextrin for later use, and uniformly stirring the Chinese herbal medicine thick paste, the sugar powder and the dextrin according to the weight ratio of 1:3:1 to obtain a finished product.
Example 3: a traditional Chinese medicine health product for delaying senility is composed of the following raw materials: 10 g of raw green tea, 10 g of liquorice, 10 g of medlar, 10 g of cassia seed, 10 g of tuckahoe, 10 g of raw hawthorn, 10 g of mulberry, 12 g of daidaidai flower, 12 g of kudzuvine root, 10 g of giant knotweed, 10 g of lucid ganoderma, 10 g of rhizoma polygonati, 10 g of chrysanthemum and 15 g of Chinese date.
The invention relates to a method for preparing an oral liquid from a traditional Chinese medicine health product for delaying senility, which comprises the following steps: preparing Chinese herbal medicine soft extract according to the same process as that for preparing the medicinal granules, diluting the soft extract with appropriate amount of distilled water, filtering, adding sucrose and potassium sorbate to obtain oral liquid product, wherein the crude drug content of the diluted solution is 30%.
Example 4: a traditional Chinese medicine health product for delaying senility is composed of the following raw materials: 5 g of raw green tea, 7 g of liquorice, 6 g of medlar, 9 g of cassia seed, 8 g of tuckahoe, 6 g of raw hawthorn, 8 g of mulberry, 10 g of daidaidai flower, 11 g of kudzuvine root, 9 g of giant knotweed rhizome, 9 g of lucid ganoderma, 7 g of rhizoma polygonati, 8 g of chrysanthemum and 12 g of Chinese date.
The invention relates to a preparation method of a Chinese medicinal health product for delaying senility, which is prepared into medicinal granules, and the preparation method comprises the following steps: according to the formula amount, removing impurities from the Chinese herbal medicine raw materials, mixing and crushing the raw materials into coarse powder (5-10 meshes), putting the coarse powder into an extraction tank, adding water which is 3 times of the weight of the raw materials, boiling the coarse powder for one hour with slow fire, filtering out liquid medicine, then adding water which is three times of the weight of the Chinese herbal medicine, boiling the fine powder for another half hour with slow fire, filtering out liquid medicine, combining the front liquid medicine and the back liquid medicine, cooling, adding ethanol which is 1-2 times of the weight of the Chinese herbal medicine and has the concentration of 90%, fully mixing the mixture, standing the mixture and precipitating the mixture; collecting supernatant after 24 hr, washing precipitate with small amount of 50-60% ethanol, mixing the washing solution with the filtrate, recovering ethanol under reduced pressure, concentrating until the crude drug content is 25%, cooling, standing for 15 hr to precipitate completely, filtering, evaporating the filtrate at low temperature to obtain soft extract with specific gravity hot side (80-90 deg.C) of 1.30-1.35; grinding sucrose crystals into fine powder, sieving with a 80-100 mesh sieve for later use, taking commercial dextrin for later use, and uniformly stirring the Chinese herbal medicine thick paste, the sugar powder and the dextrin according to the weight ratio of 1:3:1 to obtain a finished product.
Example 5: a traditional Chinese medicine health product for delaying senility is composed of the following raw materials: 9 g of raw green tea, 8 g of liquorice, 6 g of medlar, 7 g of cassia seed, 6 g of tuckahoe, 9 g of raw hawthorn, 6 g of mulberry, 11 g of daidaidai flower, 7 g of kudzu root, 8 g of giant knotweed, 7 g of lucid ganoderma, 9 g of rhizoma polygonati, 6 g of chrysanthemum and 14 g of Chinese date.
The invention relates to a method for preparing an oral liquid from a traditional Chinese medicine health product for delaying senility, which comprises the following steps: preparing Chinese herbal medicine soft extract according to the same process as that for preparing the medicinal granules, diluting the soft extract with appropriate amount of distilled water, filtering, adding sucrose and potassium sorbate to obtain oral liquid product, wherein the crude drug content of the diluted solution is 30%.
The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications of equivalent structures and equivalent processes performed by the present invention in the specification and the content of the embodiment, or directly or indirectly applied to other related technical fields, are included in the scope of the present invention.

Claims (4)

1. A traditional Chinese medicine health product for delaying senility is characterized in that: the feed consists of the following raw materials: 5-10 g of raw green tea, 5-10 g of liquorice, 5-10 g of medlar, 5-10 g of cassia seed, 5-10 g of tuckahoe, 5-10 g of raw hawthorn, 5-10 g of mulberry, 10-12 g of daidaidaidai flower, 5-12 g of kudzuvine root, 5-10 g of giant knotweed rhizome, 5-10 g of lucid ganoderma, 5-10 g of rhizoma polygonati, 5-10 g of chrysanthemum and 10-15 g of Chinese date.
2. The traditional Chinese medicine health product for delaying senescence of claim 1, which is characterized in that: the traditional Chinese medicine for delaying senescence is prepared from the following raw materials: 6-9 g of raw green tea, 6-9 g of liquorice, 6-9 g of wolfberry, 6-9 g of cassia seed, 6-9 g of poria cocos, 6-9 g of raw hawthorn, 6-9 g of mulberry, 11-12 g of daidaidaidai flower, 7-10 g of kudzu root, 6-9 g of giant knotweed rhizome, 6-9 g of lucid ganoderma, 6-9 g of rhizoma polygonati, 6-9 g of chrysanthemum and 11-14 g of Chinese date.
3. The traditional Chinese medicine health product for delaying senescence of claim 1, which is characterized in that: the traditional Chinese medicine for delaying senescence is prepared from the following raw materials: 8 g of raw green tea, 8 g of liquorice, 8 g of medlar, 8 g of cassia seed, 8 g of tuckahoe, 8 g of raw hawthorn, 8 g of mulberry, 11 g of daidaidai flower, 9 g of kudzuvine root, 8 g of giant knotweed, 8 g of lucid ganoderma, 8 g of rhizoma polygonati, 8 g of chrysanthemum and 13 g of Chinese date.
4. A preparation method of a traditional Chinese medicine health product for delaying senility is characterized by comprising the following steps: the preparation method comprises three preparation methods:
(1) preparing a tea preparation: removing impurities from the medicines, oven drying, pulverizing, mixing, sieving, packaging into sterilized filter tea bag, and sealing; the tea bag is provided with a traction and lifting short line.
(2) Preparing into granules: according to the formula amount, removing impurities from the Chinese herbal medicine raw materials, mixing and crushing the raw materials into coarse powder (5-10 meshes), putting the coarse powder into an extraction tank, adding water which is 3 times of the weight of the raw materials, boiling the coarse powder for one hour with slow fire, filtering out liquid medicine, then adding water which is three times of the weight of the Chinese herbal medicine, boiling the fine powder for another half hour with slow fire, filtering out liquid medicine, combining the front liquid medicine and the back liquid medicine, cooling, adding ethanol which is 1-2 times of the weight of the Chinese herbal medicine and has the concentration of 90%, fully mixing the mixture, standing the mixture and precipitating the mixture; collecting supernatant after 24 hr, washing precipitate with small amount of 50-60% ethanol, mixing the washing solution with the filtrate, recovering ethanol under reduced pressure, concentrating until the crude drug content is 25%, cooling, standing for 15 hr to precipitate completely, filtering, evaporating the filtrate at low temperature to obtain soft extract with specific gravity hot side (80-90 deg.C) of 1.30-1.35; grinding sucrose crystals into fine powder, sieving with a 80-100 mesh sieve for later use, taking commercial dextrin for later use, and uniformly stirring the Chinese herbal medicine thick paste, the sugar powder and the dextrin according to the weight ratio of 1:3:1 to obtain a finished product.
(3) Preparing oral liquid: preparing Chinese herbal medicine soft extract according to the same process as that for preparing the medicinal granules, diluting the soft extract with appropriate amount of distilled water, filtering, adding sucrose and potassium sorbate to obtain oral liquid product, wherein the diluted solution contains crude drug 30%.
CN202010282310.2A 2020-04-11 2020-04-11 A Chinese medicinal health product for delaying aging, and its preparation method Pending CN113509522A (en)

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Application publication date: 20211019