CN113487949A - In-vitro diagnosis simulation system and method - Google Patents
In-vitro diagnosis simulation system and method Download PDFInfo
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Abstract
The embodiment of the invention discloses an in vitro diagnosis simulation system and a method, wherein the system comprises: a hardware simulation subsystem and a man-machine interaction subsystem; the hardware simulation subsystem comprises a mechanical simulation module and a liquid path simulation module; the human-computer interaction subsystem is used for determining target execution operation, generating a target control instruction corresponding to the target execution operation based on the target execution operation, and sending the target control instruction to the mechanical simulation module; the mechanical simulation module is used for receiving a target control instruction sent by the man-machine interaction subsystem, triggering a target functional component corresponding to the target control instruction to trigger the submodule to operate based on the target control instruction so as to generate a liquid path driving signal, and sending the liquid path driving signal to the liquid path simulation module; and the liquid path simulation module is used for displaying the target flow direction related to the target liquid according to the liquid path driving signal. The technical scheme of the embodiment of the invention realizes the effect of intuitively displaying the in-vitro diagnosis process.
Description
Technical Field
The embodiment of the invention relates to the technical field of medical teaching, in particular to an in-vitro diagnosis simulation system and method.
Background
At present, a diagnostic instrument is generally used for whole machine teaching in the liquid path teaching of an in vitro diagnostic instrument. However, whole machine teaching can lead students to have difficulty in establishing intuitive cognition on internal key components and modules of the instrument. Moreover, the difficulty of disassembling and reassembling the whole instrument is high, and the problem that the whole instrument is damaged after reassembling is caused, so that the teaching cost is increased, and the resource waste is caused.
Because the price of the product-level in-vitro diagnostic instrument is high, it is difficult to equip each student with one instrument during teaching, and the teaching effect is influenced. Moreover, in the product-level in-vitro diagnostic apparatus, due to the consideration of technical secrecy, the key module is usually sealed, so that students cannot easily understand the working principle inside the apparatus, thereby affecting the teaching quality.
Disclosure of Invention
The embodiment of the invention provides an in-vitro diagnosis simulation system and method, which aim to realize the process of visually displaying in-vitro diagnosis and improve the technical effect of controlling convenience of each pump valve assembly.
In a first aspect, an embodiment of the present invention provides an in vitro diagnosis simulation system, including: a hardware simulation subsystem and a man-machine interaction subsystem; the hardware simulation subsystem comprises a mechanical simulation module and a liquid path simulation module; wherein,
the human-computer interaction subsystem is used for determining target execution operation, generating a target control instruction corresponding to the target execution operation based on the target execution operation, and sending the target control instruction to the mechanical simulation module;
the mechanical simulation module is respectively connected with the human-computer interaction subsystem and the liquid path simulation module, and is used for receiving a target control instruction sent by the human-computer interaction subsystem, triggering a functional component corresponding to the target control instruction to operate based on the target control instruction so as to generate a liquid path driving signal, and sending the liquid path driving signal to the liquid path simulation module;
the liquid path simulation module is used for displaying a target flow direction related to target liquid according to the liquid path driving signal; the liquid path simulation module is arranged in organic glass with the transparency larger than a preset transparency threshold value.
In a second aspect, an embodiment of the present invention further provides an in vitro diagnosis simulation method, which is applied to an in vitro diagnosis simulation system, and includes:
determining a target execution operation based on a human-computer interaction subsystem, generating a target control instruction corresponding to the target execution operation based on the target execution operation, and sending the target control instruction to a mechanical simulation module;
receiving a target control instruction sent by the human-computer interaction subsystem based on a mechanical simulation module, triggering a functional component corresponding to the target control instruction to operate based on the target control instruction so as to generate a liquid path driving signal, and sending the liquid path driving signal to a liquid path simulation module;
displaying a target flow direction related to the target liquid according to the liquid path driving signal based on a liquid path simulation module; the liquid path simulation module is arranged in organic glass with the transparency larger than a preset transparency threshold value.
The technical scheme of the embodiment of the invention determines a target execution operation through a human-computer interaction subsystem in an in-vitro diagnosis simulation system, generates a target control instruction corresponding to the target execution operation based on the target execution operation, sends the target control instruction to a mechanical simulation module, further receives the target control instruction sent by the human-computer interaction subsystem through the mechanical simulation module, triggers a target functional component corresponding to the target control instruction to trigger a submodule to operate based on the target control instruction so as to generate a liquid path driving signal, sends the liquid path driving signal to the liquid path simulation module, further displays a target flow direction related to target liquid through the liquid path simulation module according to the liquid path driving signal, solves the problems of stronger closure, lower visibility and inconvenience for in-vitro diagnosis teaching of the existing in-vitro diagnosis instrument, and realizes the process of visually displaying in-vitro diagnosis, and the technical effect of improving the control convenience of each pump valve assembly is achieved.
Drawings
In order to more clearly illustrate the technical solutions of the exemplary embodiments of the present invention, a brief description is given below of the drawings used in describing the embodiments. It should be clear that the described figures are only views of some of the embodiments of the invention to be described, not all, and that for a person skilled in the art, other figures can be derived from these figures without inventive effort.
Fig. 1 is a schematic structural diagram of an in vitro diagnosis simulation system according to an embodiment of the present invention;
fig. 2 is a schematic structural diagram of an in vitro diagnosis simulation system according to a second embodiment of the present invention;
fig. 3 is a schematic view of a visual operation interface of a human-computer interaction subsystem according to a third embodiment of the present invention;
fig. 4 is a schematic structural diagram of a power supply system according to a third embodiment of the present invention;
fig. 5 is a schematic structural diagram of a liquid circuit simulation module according to a third embodiment of the present invention;
fig. 6 is a schematic flow chart of an in vitro diagnosis simulation method according to a fourth embodiment of the present invention.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the invention and are not limiting of the invention. It should be further noted that, for the convenience of description, only some of the structures related to the present invention are shown in the drawings, not all of the structures.
Example one
Fig. 1 is a schematic structural diagram of an in-vitro diagnosis simulation system according to an embodiment of the present invention, which is applicable to in-vitro diagnosis simulation and display during in-vitro diagnosis teaching.
As shown in fig. 1, the in vitro diagnosis simulation system comprises a hardware simulation subsystem 1 and a human-computer interaction subsystem 2; the hardware simulation subsystem 1 includes a mechanical simulation module 11 and a fluid circuit simulation module 12.
The human-computer interaction subsystem 2 is used for determining target execution operation, generating a target control instruction corresponding to the target execution operation based on the target execution operation, and sending the target control instruction to the mechanical simulation module; the mechanical simulation module 11 is respectively connected with the human-computer interaction subsystem 2 and the liquid path simulation module 12, and is used for receiving a target control instruction sent by the human-computer interaction subsystem 2, triggering a functional component corresponding to the target control instruction to operate based on the target control instruction so as to generate a liquid path driving signal, and sending the liquid path driving signal to the liquid path simulation module 12; the liquid path simulation module 12 is configured to display a target flow direction related to the target liquid according to the liquid path driving signal; the liquid path simulation module 12 is disposed in the organic glass with the transparency greater than the preset transparency threshold.
And the human-computer interaction subsystem 2 is used for determining target execution operation and generating a target control instruction corresponding to the target execution operation based on the target execution operation.
The target execution operation may be sampling operation, sample adding operation, mixing operation, reaction operation or cleaning operation, and the like, which can be executed during in vitro diagnosis. The target control instruction may be an instruction for controlling execution of the target execution operation.
Specifically, the user can input a target to execute the operation through the human-computer interaction subsystem 2. When the target execution operation input by the user is detected, the target execution operation is determined, and a target control instruction corresponding to the target execution operation is generated to operate the subsequent control functional component.
And the mechanical simulation module 11 is respectively connected with the human-computer interaction subsystem 2 and the liquid path simulation module 12, and is used for receiving a target control instruction sent by the human-computer interaction subsystem 2, triggering a functional component corresponding to the target control instruction to operate based on the target control instruction so as to generate a liquid path driving signal, and sending the liquid path driving signal to the liquid path simulation module 12.
Wherein the target feature trigger submodule may be a submodule for generating a signal for driving the feature to operate. The functional components may be a stepping motor, a diaphragm pump, an electromagnetic valve, etc. installed in the liquid path simulation module 12 for regulating the flow of the target liquid. The fluid path drive signal may be a drive signal for triggering operation of the functional component.
Specifically, the mechanical simulation module 11 is connected to the human-computer interaction subsystem 2 to receive a target control command sent from the human-computer interaction subsystem 2. The mechanical simulation module 11 is connected to the liquid path simulation module 12 to send a liquid path driving signal to the liquid path simulation module 12. When the mechanical simulation module 11 receives the target control instruction, it may trigger the corresponding target functional component trigger sub-module to operate according to the target control instruction, so that the target functional component trigger sub-module generates a liquid path driving signal, and sends the liquid path driving signal to the liquid path simulation module 12 to control the corresponding functional component to operate.
The liquid path simulation module 12 is configured to display a target flow direction related to the target liquid according to the liquid path driving signal; the liquid path simulation module 12 is disposed in the organic glass with the transparency greater than the preset transparency threshold.
The target liquid may be a liquid used in vitro diagnostic simulation, such as: cleaning solution, reaction substance dissolving solution, sample pretreatment solution, color developing solution and the like. The target flow direction may be a flow direction of the target liquid. The preset transparency threshold value can be a preset transparency, and when the actual transparency is larger than the preset transparency threshold value, a user can clearly and visually see the flowing condition, the reaction condition and the like of the target liquid in the organic glass.
Specifically, when the liquid path simulation module 12 receives the liquid path driving signal, the corresponding functional component is triggered to operate according to the liquid path driving signal, so that the target liquid can flow in the organic glass. And, because the transparency of organic glass is greater than and predetermines the transparency threshold value, then can make the user can observe the flow and the action condition of target liquid in organic glass to when carrying out the teaching simulation, the student can have more audio-visual understanding to external diagnosis.
The technical scheme of the embodiment of the invention determines a target execution operation through a human-computer interaction subsystem in an in-vitro diagnosis simulation system, generates a target control instruction corresponding to the target execution operation based on the target execution operation, sends the target control instruction to a mechanical simulation module, further receives the target control instruction sent by the human-computer interaction subsystem through the mechanical simulation module, triggers a target functional component corresponding to the target control instruction to trigger a submodule to operate based on the target control instruction so as to generate a liquid path driving signal, sends the liquid path driving signal to the liquid path simulation module, further displays a target flow direction related to target liquid through the liquid path simulation module according to the liquid path driving signal, solves the problems of stronger closure, lower visibility and inconvenience for in-vitro diagnosis teaching of the existing in-vitro diagnosis instrument, and realizes the process of visually displaying in-vitro diagnosis, and the technical effect of improving the control convenience of each pump valve assembly is achieved.
Example two
Fig. 2 is a schematic structural diagram of an in vitro diagnosis simulation system according to a second embodiment of the present invention, wherein explanations of the same or corresponding terms as those in the first embodiment are omitted.
As shown in fig. 2, the in vitro diagnosis simulation system comprises a hardware simulation subsystem 1 and a human-computer interaction subsystem 2; the hardware simulation subsystem 1 includes a mechanical simulation module 11 and a fluid circuit simulation module 12. The human-computer interaction subsystem 2 comprises a display screen 21. The mechanical simulation module 11 includes a main control board 111, a main control sub-module 112, and at least one target functional unit triggering sub-module 113, where the main control sub-module 112 and each target functional unit triggering sub-module 113 are installed on the main control board 111. The liquid path simulation module 12 includes a transparent liquid path plate 121, a pump valve assembly 122 and a transparent pipeline 123.
And the human-computer interaction subsystem 2 is used for determining target execution operation, generating a target control instruction corresponding to the target execution operation based on the target execution operation, and sending the target control instruction to the mechanical simulation module.
Optionally, the human-computer interaction subsystem 2 includes a display screen 21; the display screen 21 is used for displaying a visual operation interface of the human-computer interaction subsystem 2, and the visual operation interface comprises a liquid path display area and a control parameter triggering area.
Among them, the display screen may be a display device having a display function, and a function of receiving and transmitting a signal, such as: the touch screen can be a display device of the intelligent equipment or an independent touch screen. The visual operation interface can display a schematic diagram of the liquid path simulation module 12 and can also display controls which can be operated by a user. The fluid path display area may be a schematic diagram of the fluid path simulation module 12, and may further include an operation state of each component schematic diagram, and the like. The control parameter triggering area may be an area that can be operated by a user to send a target control instruction to the mechanical simulation module 11 by triggering a control in the area.
Next, a control of a control parameter trigger area in the visual operation interface may be specifically introduced, and optionally, the control parameter trigger area includes a target operation type control corresponding to each target execution operation, a target parameter control corresponding to each target execution operation, a start control, and a stop control.
The target operation type control can be a control for executing various different types of operations, the operation types can include operations such as sampling, sample adding, reaction, heating, stirring, cleaning and the like, and the specific operation types can be set according to actual requirements. The target parameter control may be a control for adjusting each adjustable parameter in the target performing operation, the adjustable parameter may be a parameter such as running time, rotating speed, temperature, dosage, etc., and the adjustable parameter corresponding to different target performing operations is usually different. The launch control may be a control for controlling the launch of the current target execution operation. The stop control may be a control for controlling the stop of the current target execution operation.
Specifically, the user may trigger a control corresponding to the target execution operation in the target operation type controls according to the target execution operation that is currently desired to be executed, and set an adjustable parameter corresponding to the target execution operation through the target parameter control. Furthermore, the trigger start control may send a target control instruction to the mechanical simulation module 11 to make the target liquid in the liquid path simulation module 12 flow or react. The manner of stopping the target execution operation may be: when the execution time period of the target execution operation reaches a default time period or a user-input running time, a target control instruction to stop the target execution operation may be sent to the machine simulation module 11. Alternatively, when it is detected that the user triggers the stop control, a target control instruction for stopping the target execution operation may be generated and sent to the mechanical simulation module 11.
Optionally, a schematic diagram of the liquid path simulation module 12 may be displayed in the liquid path display area. It is also possible to use different labels, for example: colors, etc., to indicate the execution of each functional component in the fluid path simulation module 12. For example: in the schematic diagram, functional parts that are not in an operating state are marked with white, and functional parts that are in an operating state are marked with green, and the like. Through different marks, the student user can quickly and accurately know which functional component is currently running, and the student user can understand the flow, reaction and the like in the in-vitro diagnosis more conveniently.
Optionally, the target execution operation may be determined through the visual operation interface of the human-computer interaction subsystem 2 in the following two ways:
in the first mode, the human-computer interaction subsystem 2 is used for receiving a simulation teaching target input by a user based on a visual operation interface and determining at least one target execution operation according to the simulation teaching target.
The simulation teaching targets may be preset teaching targets, each teaching target may include one or more target execution operations, and optionally, the target execution operations may have a fixed order and fixed parameters.
Specifically, the simulation teaching target may be established in advance, corresponding target execution operations may be set for the simulation teaching target, and the target execution operations may be arranged in sequence. When receiving a simulation teaching target input by a user based on the visual operation interface, target execution operations corresponding to the simulation teaching target can be determined, and the target execution operations are sequentially executed.
Illustratively, the at least one target execution operation corresponding to the simulation teaching target X is a target trial operation a, a target execution operation F, a target execution operation a, a target execution operation B, and a target execution operation E. When the user inputs the simulation teaching target X based on the visual operation interface, the target execution operation and the sequence of the target execution operation, that is, the target trial operation a, the target execution operation F, the target execution operation a, the target execution operation B, and the target execution operation E, may be determined.
And a second mode is that the target operation type input by the user based on the visual operation interface and the target parameter corresponding to the target operation type are received, and the target execution operation is generated according to the target operation type and the target parameter corresponding to the target operation type.
The target parameter may be one or more adjustable parameters for setting the target execution operation.
Specifically, the user can input the target operation type based on the visual operation interface, and set the target parameter of the target operation type according to the requirement, so that the subsequently generated target execution operation meets the user requirement. Further, a target execution operation including the target operation type and the target parameter can be generated based on the input target operation type and the target parameter.
It should be noted that, by means of the first mode, the target execution operations frequently used in the teaching process can be combined, and the situation that the teacher user sets the target execution operations repeatedly can be avoided. Through the mode two, the target setting execution operation can be performed in steps, and the effect of explaining for students in one step can be achieved. The specific mode of using is taught, can select according to the teaching demand. For example: the whole process of a certain simulation teaching target can be displayed in a first mode, and the disassembling demonstration and the like are carried out in two steps in a second mode.
And the mechanical simulation module 11 is respectively connected with the human-computer interaction subsystem 2 and the liquid path simulation module 12, and is used for receiving a target control instruction sent by the human-computer interaction subsystem 2, triggering a functional component corresponding to the target control instruction to operate based on the target control instruction so as to generate a liquid path driving signal, and sending the liquid path driving signal to the liquid path simulation module 12.
Optionally, the mechanical simulation module 11 includes a main control board 111, a main control sub-module 112, and at least one target functional unit triggering sub-module 113, where the main control sub-module 112 and each target functional unit triggering sub-module 113 are both installed on the main control board 111; wherein,
the main control sub-module 112 is configured to receive a target control instruction sent by the human-computer interaction sub-system 2, determine a target functional unit trigger sub-module 113 corresponding to the target control instruction according to the target control instruction, and send the target control instruction to the target functional unit trigger sub-module 113;
the target functional unit triggering sub-module 113 is configured to receive a target control instruction sent by the main control sub-module 112, and generate a liquid path driving signal for driving the target functional unit in the liquid path simulation module 12 to work according to the target control instruction.
Specifically, the main control sub-module 112 and each target functional unit triggering sub-module 113 may be mounted on the main control board 111, and may be mounted by welding or the like. The master control sub-module 112 may receive the target control instruction and determine to which target feature the target control instruction is assigned to trigger the sub-module 113. Further, the target control command is distributed by the main control sub-module 112. When the target functional unit triggering sub-module 113 receives the target control instruction, the target control instruction may be analyzed, and a liquid path driving signal for driving the target functional unit in the liquid path simulation module 12 may be generated, so as to change the operating state of the target functional unit.
Optionally, the target function component triggering sub-module 113 includes at least one of a stepper motor driving sub-module, a pump valve driving sub-module, and an optical coupling sensor.
The step motor driving sub-module can be a driving module for controlling the step motor to work, the pump valve driving sub-module can be a driving module for controlling pump valve assemblies such as a plunger pump, a diaphragm pump and an electromagnetic valve to work, and the optical coupling sensor can be a device for transmitting an electric signal by taking light as a medium.
The liquid path simulation module 12 is configured to display a target flow direction related to the target liquid according to the liquid path driving signal; the liquid path simulation module 12 is disposed in the organic glass with the transparency greater than the preset transparency threshold.
Optionally, the fluid path simulation module 12 includes a transparent fluid path plate 121, a pump valve assembly 122, and a transparent pipeline 123.
The transparent liquid channel plate 121 may be organic glass with a transparency greater than a preset transparency threshold. The pump and valve assembly 122 may be an assembly installed in the transparent liquid path plate 121 for controlling the target liquid to perform a target performing operation. The transparent pipe 123 may be a pipe in the transparent liquid passage plate 121, connecting each pump valve assembly 122, so that the target liquid can flow in the transparent pipe 123.
Optionally, the pump-valve assembly 122 includes at least one of a high-precision metering pump, a solenoid valve, a diaphragm pump, and a rotary air pump.
Wherein, high accuracy measurement pump can be the precision height, the good pump package of leakproofness. The solenoid valve can be an industrial device controlled by electromagnetism, and is an automatic basic element for controlling a target liquid. The diaphragm pump may be an assembly that protects the plunger and the pump cylinder by separating the target liquid from the plunger and the pump cylinder by means of a membrane. The rotary air pump may be a pump assembly for introducing air into the fluid circuit emulation module 12.
It should be noted that the pump valve assembly may also include other components that may be used in vitro diagnostics, and are not illustrated herein.
Optionally, the transparent liquid channel plate 121 is formed by a multi-manifold substrate, wherein the multi-manifold substrate includes at least two layers of three-dimensional flow paths.
The multi-manifold substrate can realize more than 2 layers of three-dimensional flow paths, and a three-dimensional liquid path structure which cannot be finished by conventional machining is formed. The transparent liquid path board constructed by the component has the advantages of simple liquid path, stability, reliability, compact structure, easy maintenance and the like.
It should be noted that the mode that transparent pipeline 123 is integrated inside the organic glass is favorable to the teacher to carry out liquid way principle teaching, and the design that does not have the removal pipeline has advantages such as reliable and stable, compact structure, easy maintenance again, is fit for using in the teaching instrument.
The technical scheme of the embodiment of the invention determines a target execution operation through a human-computer interaction subsystem in an in-vitro diagnosis simulation system, generates a target control instruction corresponding to the target execution operation based on the target execution operation, sends the target control instruction to a mechanical simulation module, further receives the target control instruction sent by the human-computer interaction subsystem through the mechanical simulation module, triggers a target functional component corresponding to the target control instruction to trigger a submodule to operate based on the target control instruction so as to generate a liquid path driving signal, sends the liquid path driving signal to the liquid path simulation module, further displays a target flow direction related to target liquid through the liquid path simulation module according to the liquid path driving signal, solves the problems of stronger closure, lower visibility and inconvenience for in-vitro diagnosis teaching of the existing in-vitro diagnosis instrument, and realizes the process of visually displaying in-vitro diagnosis, and the technical effect of improving the control convenience of each pump valve assembly is achieved.
EXAMPLE III
Fig. 3 is a schematic view of a visual operation interface of a human-computer interaction subsystem according to a third embodiment of the present invention. The same or corresponding terms as those in the above embodiments are not explained in detail herein.
As shown in fig. 3, the visual operation interface includes a liquid path display area located in the central portion, and a control parameter trigger area disposed around the liquid path display area.
The precision calibration, the sampling A, the sample adding A, the sampling B and the sample adding B are target operation type controls which execute operation with each target. And in the operation interface, the parameter setting control is a target parameter control corresponding to each target execution operation. The system can also comprise a starting control, a stopping control, a homepage control, a manual/automatic adjusting control, a next step control and the like.
Optionally, the human-computer interaction subsystem may be a human-computer interaction system based on an Android platform. The user can operate and develop the in vitro diagnosis on the visual operation interface, and can carry out independent program design and program writing according to debugging requirements, so as to further improve the software design capability of the user and the understanding of the in vitro diagnosis liquid path.
Optionally, the human-computer interaction subsystem can be developed by using a C #, and written based on a WinForm framework.
Fig. 4 is a schematic structural diagram of a power supply system according to a third embodiment of the present invention. The same or corresponding terms as those in the above embodiments are not explained in detail herein.
As shown in fig. 4, the display screen in the human-computer interaction subsystem, the main control sub-module in the mechanical simulation module, and the trigger sub-modules of the target functional components may be powered by an external power supply or an internal power supply. The display screen may be a WinForm based liquid crystal display. And the main control sub-module can send the working state of each target functional component to the display screen and acquire and analyze the target control instruction sent by the man-machine interaction sub-system. The main control sub-module can control each target functional component to trigger the sub-module to work.
Optionally, the mechanical simulation module may be composed of a main control sub-module, a stepping motor driving sub-module, a pump valve driving sub-module, an optical coupling sensor, and the like.
Illustratively, the main control sub-module may adopt STM32F103RCT6 of ST corporation as a control core to meet the functions and requirements of the whole system. The pump valve driving sub-module corresponding to the high-precision injector and the plunger pump can select a TMC5130 driver, a chip of the driver has 256 micro-step subdivision, an advanced stepping motor motion algorithm is integrated, and the high-precision injector and the plunger pump have high portability. The pump valve driving submodule corresponding to the diaphragm pump and the electromagnetic valve can adopt an IRF7313 type double-channel MOS tube.
Fig. 5 is a schematic structural diagram of a liquid circuit simulation module according to a third embodiment of the present invention. The same or corresponding terms as those in the above embodiments are not explained in detail herein.
As shown in fig. 5, the liquid path simulation module includes target functional components such as a high-precision metering pump, an electromagnetic valve, a diaphragm pump, a rotary air pump, and a pipeline, and basically covers common components for in vitro diagnosis teaching. Also shown in figure 5 are the various reagents, cleaning fluids, waste fluids and air flow lines. The pipeline A is a reagent 1 pipeline, the pipeline B is a reagent 2 pipeline, the pipeline C is an air pipeline, the pipeline D is a cleaning liquid pipeline, and the pipeline E is a waste liquid pipeline.
The liquid path simulation module is different from the traditional form of 'soft and hard pipelines + joints + pump valve assemblies', adopts a multi-manifold substrate formed by bonding multiple layers of organic glass (PMMA), and can realize more than 2 layers of three-dimensional flow paths to form a three-dimensional liquid path structure which cannot be finished by conventional machining. The mode of integrating the transparent pipeline into the organic glass is beneficial for teachers to carry out teaching of the liquid path principle; the design of no removal pipeline has advantages such as reliable and stable, compact structure, easy maintenance, is fit for using in colleges and universities' teaching instrument.
The technical scheme of this embodiment has compensatied the not enough of external diagnosis in instrument principle teaching to transparent organic glass is the major structure, integrates the complicated liquid way system among the external diagnostic apparatus, has integrated key parts commonly used of external diagnostic apparatus such as high accuracy syringe, plunger pump, diaphragm pump, solenoid valve simultaneously, adopts brand-new teaching mode, lets the student know the theory of operation of liquid way system directly perceivedly, learns the application method of key parts such as plunger pump, solenoid valve, deepens the understanding to external diagnostic apparatus.
Example four
Fig. 6 is a schematic flow chart of an in-vitro diagnosis simulation method according to a fourth embodiment of the present invention, which is applicable to an in-vitro diagnosis simulation system and is used for performing in-vitro diagnosis simulation and display during in-vitro diagnosis teaching. The same or corresponding terms as those in the above embodiments are not explained in detail herein.
As shown in fig. 6, the method of this embodiment specifically includes the following steps:
s610, determining target execution operation based on the man-machine interaction subsystem, generating a target control instruction corresponding to the target execution operation based on the target execution operation, and sending the target control instruction to the mechanical simulation module.
Optionally, the human-computer interaction subsystem includes a display screen; the display screen is used for displaying a visual operation interface of the man-machine interaction subsystem, and the visual operation interface comprises a liquid path display area and a control parameter triggering area.
Optionally, the control parameter triggering area includes a target operation type control corresponding to each target execution operation, a target parameter control corresponding to each target execution operation, a start control, and a stop control.
Optionally, the human-computer interaction-based subsystem receives a simulation teaching target input by a user based on the visual operation interface, and determines at least one target execution operation according to the simulation teaching target; or receiving a target operation type input by a user based on the visual operation interface and a target parameter corresponding to the target operation type, and generating a target execution operation according to the target operation type and the target parameter corresponding to the target operation type.
And S620, receiving a target control instruction sent by the man-machine interaction subsystem based on the mechanical simulation module, triggering a functional component corresponding to the target control instruction to operate based on the target control instruction so as to generate a liquid path driving signal, and sending the liquid path driving signal to the liquid path simulation module.
Optionally, the mechanical simulation module includes a main control board, a main control sub-module and at least one target functional unit trigger sub-module, where the main control sub-module and each target functional unit trigger sub-module are installed on the main control board;
receiving a target control instruction sent by the man-machine interaction subsystem based on a main control sub-module, determining a target functional component trigger sub-module corresponding to the target control instruction according to the target control instruction, and sending the target control instruction to the target functional component trigger sub-module;
and receiving a target control instruction sent by the main control sub-module based on a target functional component trigger sub-module, and generating a liquid path driving signal for driving a target functional component in the liquid path simulation module to work according to the target control instruction.
Optionally, the target function component triggering sub-module includes at least one of a stepper motor driving sub-module, a pump valve driving sub-module, and an optical coupling sensor.
S630, displaying a target flow direction related to the target liquid based on the liquid path simulation module according to the liquid path driving signal; the liquid path simulation module is arranged in the organic glass with the transparency larger than the preset transparency threshold value.
Optionally, the liquid path simulation module includes a transparent liquid path plate, a pump valve assembly and a transparent pipeline.
Optionally, the pump-valve assembly comprises at least one of a high precision metering pump, a solenoid valve, a diaphragm pump and a rotary air pump.
Optionally, the transparent liquid channel plate is composed of a multi-manifold substrate, wherein the multi-manifold substrate includes at least two layers of three-dimensional flow paths.
The technical scheme of the embodiment of the invention determines a target execution operation through a human-computer interaction subsystem in an in-vitro diagnosis simulation system, generates a target control instruction corresponding to the target execution operation based on the target execution operation, sends the target control instruction to a mechanical simulation module, further receives the target control instruction sent by the human-computer interaction subsystem through the mechanical simulation module, triggers a target functional component corresponding to the target control instruction to trigger a submodule to operate based on the target control instruction so as to generate a liquid path driving signal, sends the liquid path driving signal to the liquid path simulation module, further displays a target flow direction related to target liquid through the liquid path simulation module according to the liquid path driving signal, solves the problems of stronger closure, lower visibility and inconvenience for in-vitro diagnosis teaching of the existing in-vitro diagnosis instrument, and realizes the process of visually displaying in-vitro diagnosis, and the technical effect of improving the control convenience of each pump valve assembly is achieved.
It is to be noted that the foregoing is only illustrative of the preferred embodiments of the present invention and the technical principles employed. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the invention. Therefore, although the present invention has been described in greater detail by the above embodiments, the present invention is not limited to the above embodiments, and may include other equivalent embodiments without departing from the spirit of the present invention, and the scope of the present invention is determined by the scope of the appended claims.
Claims (10)
1. An in vitro diagnostic simulation system, comprising: a hardware simulation subsystem and a man-machine interaction subsystem; the hardware simulation subsystem comprises a mechanical simulation module and a liquid path simulation module; wherein,
the human-computer interaction subsystem is used for determining target execution operation, generating a target control instruction corresponding to the target execution operation based on the target execution operation, and sending the target control instruction to the mechanical simulation module;
the mechanical simulation module is respectively connected with the human-computer interaction subsystem and the liquid path simulation module, and is used for receiving a target control instruction sent by the human-computer interaction subsystem, triggering a target functional component triggering submodule corresponding to the target control instruction to operate based on the target control instruction so as to generate a liquid path driving signal, and sending the liquid path driving signal to the liquid path simulation module;
the liquid path simulation module is used for displaying a target flow direction related to target liquid according to the liquid path driving signal; the liquid path simulation module is arranged in organic glass with the transparency larger than a preset transparency threshold value.
2. The system of claim 1, wherein the mechanical simulation module comprises a main control board, a main control sub-module, and at least one target functional unit trigger sub-module, the main control sub-module and each target functional unit trigger sub-module being mounted on the main control board; wherein,
the main control sub-module is used for receiving a target control instruction sent by the man-machine interaction sub-system, determining a target functional component trigger sub-module corresponding to the target control instruction according to the target control instruction, and sending the target control instruction to the target functional component trigger sub-module;
the target functional component triggering sub-module is used for receiving a target control instruction sent by the main control sub-module and generating a liquid path driving signal for driving a target functional component in the liquid path simulation module to work according to the target control instruction.
3. The system of claim 2, wherein the target feature activation submodule comprises at least one of a stepper motor drive submodule, a pump valve drive submodule, and an opto-coupler sensor.
4. The system of claim 1, wherein the fluid circuit emulation module comprises a transparent fluid circuit board, a pump valve assembly, and a transparent tubing.
5. The system of claim 4, wherein the pump-valve assembly comprises at least one of a high-precision metering pump, a solenoid valve, a diaphragm pump, and a rotary air pump.
6. The system of claim 4, wherein the transparent fluidic plate is comprised of a multi-manifold substrate, wherein the multi-manifold substrate comprises at least two layers of three-dimensional fluidic circuits.
7. The system of claim 1, wherein the human-computer interaction subsystem comprises a display screen; the display screen is used for displaying a visual operation interface of the man-machine interaction subsystem, and the visual operation interface comprises a liquid path display area and a control parameter triggering area.
8. The system of claim 7, wherein the control parameter trigger area comprises a target operation type control corresponding to each target execution operation, a target parameter control corresponding to each target execution operation, a start control, and a stop control.
9. The system of claim 7, wherein the human-computer interaction subsystem is configured to receive a simulated teaching objective input by a user based on the visual operation interface, and determine at least one objective execution operation according to the simulated teaching objective; or receiving a target operation type input by a user based on the visual operation interface and a target parameter corresponding to the target operation type, and generating a target execution operation according to the target operation type and the target parameter corresponding to the target operation type.
10. An in vitro diagnosis simulation method is applied to an in vitro diagnosis simulation system, and comprises the following steps:
determining a target execution operation based on a human-computer interaction subsystem, generating a target control instruction corresponding to the target execution operation based on the target execution operation, and sending the target control instruction to a mechanical simulation module;
receiving a target control instruction sent by the man-machine interaction subsystem based on a mechanical simulation module, triggering a target functional component triggering sub-module corresponding to the target control instruction to operate based on the target control instruction so as to generate a liquid path driving signal, and sending the liquid path driving signal to a liquid path simulation module;
displaying a target flow direction related to the target liquid according to the liquid path driving signal based on a liquid path simulation module; the liquid path simulation module is arranged in organic glass with the transparency larger than a preset transparency threshold value.
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