CN113456708A - Medicine for treating toothache and preparation method thereof - Google Patents

Medicine for treating toothache and preparation method thereof Download PDF

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Publication number
CN113456708A
CN113456708A CN202110788998.6A CN202110788998A CN113456708A CN 113456708 A CN113456708 A CN 113456708A CN 202110788998 A CN202110788998 A CN 202110788998A CN 113456708 A CN113456708 A CN 113456708A
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parts
days
liquor
grain
toothache
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杨小林
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/41Crassulaceae (Stonecrop family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/59Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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  • Health & Medical Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
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Abstract

The invention discloses a preparation method of a medicament for treating toothache, which comprises the following steps: s1: frying 30-40 parts of fresh stevia rebaudiana, 15-20 parts of menthol, 10-15 parts of astragalus membranaceus, 8-10 parts of asarum, 10-15 parts of radix paeoniae alba, 1-3 parts of fingernail and 3-4 parts of chrysanthemum on slow fire, drying in the air, and then grinding to prepare dispensing powder; s2: adding the dosage powder into Chinese liquor of 48-52 degree, sealing in a container, soaking for 30-50 days, and shaking once every two days; the white spirit is strong aromatic white spirit or Maotai-flavor white spirit, and the alcohol content of the white spirit is 45 degrees or 52 degrees. The grain medicinal liquor is prepared by frying the prepared drug with slow fire, drying in the air and then grinding to obtain prepared drug powder; adding the dosage powder into Chinese liquor of 48-52 degree, sealing in a container, soaking for 30-50 days, and shaking once every two days; filtering the above wine residue to obtain juice, and making into grain medicated liquor. When the elephantopus scaber is used, impurities are removed, the elephantopus scaber is soaked in water until the internal humidity and the external humidity are uniform, the elephantopus scaber is taken out, the elephantopus scaber is sliced or cut into small blocks, and the elephantopus scaber is dried in the sun.

Description

Medicine for treating toothache and preparation method thereof
Technical Field
The invention relates to a medicament for treating toothache and a preparation method thereof, in particular to a medicament for treating toothache and a preparation method thereof.
Background
Toothache (toothaches) is one of the common symptoms of oral diseases due to various causes of tooth, and is found in dental caries, pulpitis, periapical periodontitis, dentinal hypersensitivity and the like in western medicine. Toothache is attacked or aggravated when the toothache is stimulated by cold, heat, acid, sweet and the like, and belongs to the categories of 'Xuan' and 'alveolar wind' in the traditional Chinese medicine. Toothache is a disease marked by red, swollen and painful teeth and gums. It is caused by unclean oral cavity, thick taste of paste, accumulated heat in stomach, and upsurging stomach fire, or invasion and injury of pathogenic wind and fire, or deficiency of kidney-yin, flaring up of deficient fire, and burning gum. Toothache is a common disease, which often occurs in young and middle-aged. Due to repeated attacks, great pain is brought to the patient. Some patients are not easy to cure for several months, years or more than ten years.
Toothache onset should be regarded as important and treated early, and complications can be prevented by adopting a correct tooth treatment method. At present, a number of methods for treating toothache are available, and an appropriate method can be selected according to the condition of the patient. Western medicine treatment: oral analgesic such as tranquilizer including diazepam and chlordiazepoxide, or temporary analgesic such as aspirin, pain relieving tablet, Notoginseng radix tablet, and Yunnan white drug powder. Or surgical treatment, tooth washing and scraping and extraction of the affected tooth, which have limitations. The existing traditional Chinese medicine treatment has high recurrence rate.
Toothache is one of the most common symptoms of dental diseases in the stomatology department. Toothache is caused by infection of teeth, mostly by gingivitis, periodontitis, tooth decay or broken teeth. Toothache is an extrinsic reaction of dental caries, which may be a caries, a tooth pulp or a gingival infection around canine teeth.
The toothache should be treated with drugs first. Because there are many patients with dental pain, more than fifty percent suffer from dental pain. The children eat the decayed teeth in sixty percent to seventy percent in rural areas, no method is provided for hospitals, the children eat anti-inflammatory drugs instead of tooth extraction, the effect is not good, and side effects are caused after long-term use.
Severe pain in the teeth can in turn cause headache, ear pain, neck pain, and affect chewing and work. The traditional Chinese medicine holds that the pain caused by wind-heat stomach fire, decayed teeth and the like is the most common in the disease. It is wind-heat, manifested as gingival swelling, halitosis, constipation, dental caries, tooth pain, and pulpitis caused by deep dental caries.
Toothache is a common disease, frequently encountered. Usually, it is said that "toothache is not a disease, and it can be vital to get pain. Although toothache is not life threatening, pain is really important. Most of the medicines for treating toothache in the current market are oral analgesics, which have great side effects and slow effect, and no more medicines and dosage forms with obvious curative effects are specially used for treating and nursing toothache diseases, so that great difficulty is brought to patients in treatment, and a plurality of patients cannot be treated and nursed timely and effectively.
Disclosure of Invention
The invention aims to solve the technical problem that the market provides medicinal liquor with better toothache treatment effect, the medicinal liquor is improved on the basis of the traditional medicinal liquor formula, and a unique Chinese medicinal material formula is used through long-term test and observation to provide the medicinal liquor with obvious curative effect for treating toothache, and the invention aims to provide a medicament for treating toothache and a preparation method thereof, so that the medicament can rapidly relieve pain, shorten treatment time, reduce pain of patients and solve the problems.
The invention is realized by the following technical scheme:
a medicine for treating toothache is prepared from the following components: the food is prepared by infusing 15-30 g of the root of roxburgh rose, 10-15 g of roxburgh rose, 10 g of indigowoad root and 500g of grain medicinal liquor, wherein the grain medicinal liquor is prepared from 30-40 parts of fresh stevia rebaudiana, 15-20 parts of menthol, 10-15 parts of astragalus membranaceus, 8-10 parts of asarum, 10-15 parts of white paeony root, 1-3 parts of Buddha nail, 3-4 parts of chrysanthemum and 800-1000 parts of white spirit by weight.
The traditional Chinese medicine considers that toothache is caused by external wind evil, wind erosion of teeth, intense stomach fire, kidney deficiency and fire excess and the like. The gum is the collateral of stomach and the teeth are the excess of bone, so the pain caused by stomach fire is relieved and the kidney yin deficiency is accompanied. The chapter pion "Jingyue quan Shu" records: the six vessels are floating and big due to the excess of water and fire; deficiency of yin, excessive yang-yin, feverish dysphoria, thirst, headache, toothache, and hemorrhage. "toothache is not caused by deficiency of kidney yin and yang-fire heat.
At present, the treatment of toothache mainly adopts operation treatment and western medicine treatment, the operation treatment has large wound, and the operation treatment is generally difficult to accept by patients; western medicine treatment mainly relieves pain by taking metronidazole, fenbutate and the like, and has a good effect of temporarily relieving toothache; but has strong side effect after long-term taking, thereby further harming the health of patients. Meanwhile, regardless of adopting operation treatment or using western medicines for relieving, the treatment on the toothache only can be a temporary solution and not a permanent solution, and is difficult to treat from the source of the toothache.
At present, the toothache lotion in the traditional Chinese medicine market in China mainly contains camphor and borneol, and the camphor is toxic. Toothache lotion containing camphor component can cause toxic symptoms such as headache, nausea, emesis, etc.
Further, the white spirit is strong-flavor white spirit or Maotai-flavor white spirit, and the alcohol content of the white spirit is 45 degrees or 52 degrees.
Further, the grain medicinal liquor is prepared by frying the prepared drug with slow fire, drying in the air and then grinding to prepare prepared drug powder; adding the dosage powder into Chinese liquor of 48-52 degree, sealing in a container, soaking for 30-50 days, and shaking once every two days; filtering the above wine residue to obtain juice, and making into grain medicated liquor.
Further, when the fel Elephantus is used, impurities are removed, the fel Elephantus is soaked in water until the fel Elephantus is completely soaked in water, taken out, and cut into small pieces or dried after the internal and external humidity is uniform.
A method of preparing a medicament for treating dental pain, the method comprising the steps of: s1: frying 30-40 parts of fresh stevia rebaudiana, 15-20 parts of menthol, 10-15 parts of astragalus membranaceus, 8-10 parts of asarum, 10-15 parts of radix paeoniae alba, 1-3 parts of fingernail and 3-4 parts of chrysanthemum on slow fire, drying in the air, and then grinding to prepare dispensing powder; s2: adding the dosage powder into Chinese liquor of 48-52 degree, sealing in a container, soaking for 30-50 days, and shaking once every two days; s3: and filtering residues of the wine to obtain juice, thus obtaining the grain medicinal liquor, and soaking 15-30 g of the root of the rosa roxburghii tratt, 10-15 g of the rosa roxburghii tratt and 10 g of the scabrous elephantfoot herb in 500g of the grain medicinal liquor for at least 30 days.
Compared with the prior art, the invention has the following advantages and beneficial effects:
1. the medicine for treating toothache and the preparation method thereof have the effects of clearing away heat and toxic materials, relieving pain and diminishing inflammation, and promoting qi circulation and relieving pain. The traditional Chinese medicine composition has obvious curative effect on toothache with symptoms of gingivitis, periodontitis, dental caries or broken teeth caused by dental pulp infection and the like, is easy to obtain raw materials of medicinal materials, has good pain relieving effect, has no toxic or side effect, and has the advantages of quick action, low cost, obvious treatment effect and no relapse after healing. The clinical test result shows that when the medicine is used for treating toothache, a mild patient can be cured in 1-3 days, and a severe patient can be cured in 4-7 days, and the cure rate is as high as 98%;
2. the medicine for treating toothache and the preparation method thereof can protect teeth, prevent and treat decayed teeth, reduce symptoms of dental acid, gingival inflammation, gingival bleeding, toothache and the like, are suitable for both the old and the young, can kill teeth, and has no side effect and good effect.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to examples, and the exemplary embodiments and descriptions thereof are only used for explaining the present invention and are not used as limitations of the present invention.
Examples
The invention relates to a medicament for treating toothache, which is prepared from the following components: the food is prepared by infusing 15-30 g of the root of roxburgh rose, 10-15 g of roxburgh rose, 10 g of indigowoad root and 500g of grain medicinal liquor, wherein the grain medicinal liquor is prepared from 30-40 parts of fresh stevia rebaudiana, 15-20 parts of menthol, 10-15 parts of astragalus membranaceus, 8-10 parts of asarum, 10-15 parts of white paeony root, 1-3 parts of Buddha nail, 3-4 parts of chrysanthemum and 800-1000 parts of white spirit by weight.
The white spirit is strong aromatic white spirit or Maotai-flavor white spirit, and the alcohol content of the white spirit is 45 degrees or 52 degrees. The grain medicinal liquor is prepared by frying the prepared drug with slow fire, drying in the air and then grinding to obtain prepared drug powder; adding the dosage powder into Chinese liquor of 48-52 degree, sealing in a container, soaking for 30-50 days, and shaking once every two days; filtering the above wine residue to obtain juice, and making into grain medicated liquor. When the elephantopus scaber is used, impurities are removed, the elephantopus scaber is soaked in water until the internal humidity and the external humidity are uniform, the elephantopus scaber is taken out, the elephantopus scaber is sliced or cut into small blocks, and the elephantopus scaber is dried in the sun.
A method of preparing a medicament for treating dental pain, the method comprising the steps of: s1: frying 30-40 parts of fresh stevia rebaudiana, 15-20 parts of menthol, 10-15 parts of astragalus membranaceus, 8-10 parts of asarum, 10-15 parts of radix paeoniae alba, 1-3 parts of fingernail and 3-4 parts of chrysanthemum on slow fire, drying in the air, and then grinding to prepare dispensing powder; s2: adding the dosage powder into Chinese liquor of 48-52 degree, sealing in a container, soaking for 30-50 days, and shaking once every two days; s3: and filtering residues of the wine to obtain juice, thus obtaining the grain medicinal liquor, and soaking 15-30 g of the root of the rosa roxburghii tratt, 10-15 g of the rosa roxburghii tratt and 10 g of the scabrous elephantfoot herb in 500g of the grain medicinal liquor for at least 30 days.
The above-mentioned embodiments are intended to illustrate the objects, technical solutions and advantages of the present invention in further detail, and it should be understood that the above-mentioned embodiments are merely exemplary embodiments of the present invention, and are not intended to limit the scope of the present invention, and any modifications, equivalent substitutions, improvements and the like made within the spirit and principle of the present invention should be included in the scope of the present invention.

Claims (5)

1. The medicine for treating toothache is characterized by being prepared from the following components: the food is prepared by infusing 15-30 g of the root of roxburgh rose, 10-15 g of roxburgh rose, 10 g of indigowoad root and 500g of grain medicinal liquor, wherein the grain medicinal liquor is prepared from 30-40 parts of fresh stevia rebaudiana, 15-20 parts of menthol, 10-15 parts of astragalus membranaceus, 8-10 parts of asarum, 10-15 parts of white paeony root, 1-3 parts of Buddha nail, 3-4 parts of chrysanthemum and 800-1000 parts of white spirit by weight.
2. The medicine for treating toothache as claimed in claim 1, wherein the Chinese liquor is Luzhou-flavor Chinese liquor or Maotai-flavor Chinese liquor, and the alcohol content of the Chinese liquor is 45 degrees or 52 degrees.
3. The medicine for treating toothache as claimed in claim 1, wherein the grain liquor is prepared by parching the dosage with slow fire, air drying, and grinding to obtain dosage powder; adding the dosage powder into Chinese liquor of 48-52 degree, sealing in a container, soaking for 30-50 days, and shaking once every two days; filtering the above wine residue to obtain juice, and making into grain medicated liquor.
4. The medicine for treating toothache as claimed in claim 1, wherein the herba Sonchi Oleracei is used by removing impurities, soaking in water to obtain a solution with a certain volume, taking out, moistening to uniform humidity, slicing or cutting into small pieces, and drying in the sun.
5. A method for preparing a medicament for treating dental pain, the method comprising the steps of:
s1: frying 30-40 parts of fresh stevia rebaudiana, 15-20 parts of menthol, 10-15 parts of astragalus membranaceus, 8-10 parts of asarum, 10-15 parts of radix paeoniae alba, 1-3 parts of fingernail and 3-4 parts of chrysanthemum on slow fire, drying in the air, and then grinding to prepare dispensing powder;
s2: adding the dosage powder into Chinese liquor of 48-52 degree, sealing in a container, soaking for 30-50 days, and shaking once every two days;
s3: and filtering residues of the wine to obtain juice, thus obtaining the grain medicinal liquor, and soaking 15-30 g of the root of the rosa roxburghii tratt, 10-15 g of the rosa roxburghii tratt and 10 g of the scabrous elephantfoot herb in 500g of the grain medicinal liquor for at least 30 days.
CN202110788998.6A 2021-07-13 2021-07-13 Medicine for treating toothache and preparation method thereof Pending CN113456708A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106109856A (en) * 2016-08-16 2016-11-16 安徽天乾健食品科技有限公司 Pure Chinese prescription of one group for the treatment of toothache and preparation method thereof
CN107137521A (en) * 2017-05-26 2017-09-08 合肥丰瑞隆生物科技有限公司 Treat medicinal liquor of toothache and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106109856A (en) * 2016-08-16 2016-11-16 安徽天乾健食品科技有限公司 Pure Chinese prescription of one group for the treatment of toothache and preparation method thereof
CN107137521A (en) * 2017-05-26 2017-09-08 合肥丰瑞隆生物科技有限公司 Treat medicinal liquor of toothache and preparation method thereof

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Application publication date: 20211001