CN113440424B - Tooth paste capable of simultaneously nursing teeth and gums and preparation method thereof - Google Patents
Tooth paste capable of simultaneously nursing teeth and gums and preparation method thereof Download PDFInfo
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/29—Titanium; Compounds thereof
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- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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- A—HUMAN NECESSITIES
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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Abstract
The invention relates to the field of oral care products, in particular to a dental paste capable of simultaneously caring teeth and gums and a preparation method thereof. The dental patch of the present invention comprises a support material and a gel comprising: a tooth care portion, a gum care portion, and a transition portion; wherein the transition portion is used to separate the tooth care portion from the gum care portion and comprises 1-5wt.% nano-titania. The transition part in the dental paste can prevent the interpenetration between the tooth care part and the gum care part, can avoid the damage of the whitening component in the tooth care part to the gum, and can also prevent the phenomenon of uneven efficacy exertion caused by the interpenetration of the two parts. In addition, the tooth care part and the gum care part in the tooth paste can exert good care effects, and can better protect teeth and gums.
Description
Technical Field
The invention relates to the field of oral care products, in particular to a dental paste capable of simultaneously caring teeth and gums and a preparation method thereof.
Background
Normal healthy teeth are shiny, yellowish white, with a texture similar to ceramics. However, for various reasons, teeth may also develop discoloration. Common extrinsic staining causes of teeth are the following:
pigment in diet, such as long-term tea drinking, coffee, smoking, etc.
2, poor oral hygiene, causing external pigmentation on the tooth surface.
Certain drugs, such as chlorhexidine, can cause staining of the tooth surface.
4, occupational factors such as certain prolonged exposure to iron, sulfur, etc., color the teeth.
5, other factors, such as the growth of pigmented bacteria in the oral cavity, can contribute to exogenous staining.
Exogenous staining is one of the common factors of tooth discoloration, and at the present stage, except for treatment of medical institutions going to the profession, the main method for removing exogenous staining is to use toothpaste with whitening efficacy, whiten tooth paste or use whitening gel products.
The main action mechanism of the whitening tooth paste is to decolorize exogenous coloring matters by using a strong oxidant so as to achieve the whitening effect. However, the strong oxidizing agent, represented by peroxide, can cause some damage to the teeth themselves, such as sensitivity of the teeth, over time. In addition, if the whitening strip contacts the gum portion, the gum portion is adversely affected. Even without contacting the gums, the whitening strip product is just a non-damaging gum. During the process of whitening the teeth, the gum part is not maintained. Whitening patches are too single in efficacy and can cause tooth sensitivity as a point of pain that needs industry resolution.
The functional components aiming at tooth desensitization at the present stage are mainly divided into two types. The first is represented by a tooth remineralizing agent, and the main mechanism is to remineralize teeth by fluorine element or the like, and to block dentinal tubules, thereby reducing tooth sensitivity. The other is represented by desensitizing agents, such as potassium ions, which can be used to some extent as desensitizing agents to reduce the symptoms of dental hypersensitivity. Although such research is occurring in domestic and foreign papers, it cannot be organically combined with common products.
The daily problems of gums are mainly manifested in red and swollen gums, pain and the like. Many herbs or essential oils have some effect on this condition. Such as honeysuckle, dandelion, ginger essential oil, tea tree essential oil, propolis, etc. For daily maintenance of gums, chrysanthemum, vitamin E and its derivatives, vitamin C and its derivatives are all good choices. The gel patch prepared from the active ingredients is tightly attached to the gum, so that the active ingredients can directly contact the gum, and the efficiency of the active ingredients on the gum is improved.
In the prior art CN 112107509A, a whitening tooth paste containing hyaluronic acid is disclosed, which uses the characteristics of hyaluronic acid to care gums to achieve the purpose of preventing the damage of the whitening agent in the tooth paste to the gums. However, the dental tape does not directly contact the gums, so that it is difficult for the active ingredient to properly care for the gum region.
Disclosure of Invention
First, the technical problem to be solved
In order to avoid damage to gums by commonly used tooth care ingredients while caring teeth and gums through one dental patch, the present invention explores and provides a dental patch capable of simultaneously caring teeth and gums and a preparation method thereof.
(II) technical scheme
The present invention first provides a dental patch comprising a support material and a gel comprising: a tooth care portion, a gum care portion, and a transition portion;
wherein the transition portion is used to separate the tooth care portion from the gum care portion and comprises 1-5wt.% nano-titania.
According to the invention, the transition part containing nano titanium dioxide is additionally arranged between the tooth care part and the gum care part, so that the mutual permeation of the tooth care part and the gum care part is prevented, and the phenomena of uneven tooth whitening or gum injury and the like caused by the mutual permeation are avoided.
Preferably, the transition portion further comprises a pigment which may interact with components in the tooth care portion and/or the gum care portion and undergo a color change.
Further preferably, the pigment is methylene blue, which can be oxidatively decolorized by a whitening agent, more preferably in an amount of 0.01-0.05wt.% in the transition portion.
By adding the pigment into the transition part in the mode, whether the three parts in the tooth paste are mutually penetrated or not can be obviously observed, if so, the pigment is discolored, and the contact layer is uneven, so that the quality of the product can be checked more conveniently during production, storage, sales and use by consumers.
The choice of support material is not particularly limited in the present invention, and in a preferred embodiment, the support material is a PET film.
The dental tape of the present invention may be formed into a shape suitable for teeth of a human body, or may be formed into a sheet-like or roll-up product for consumers to cut as needed, and is not particularly limited herein.
Preferably, when the volume ratio of the tooth care part to the transition part to the gum care part is 1 (0.2-0.5): 0.8-1.2, the functions of the parts are better realized.
Preferably, the tooth care portion contains a whitening agent and a desensitizing agent;
the whitening agent is one or a combination of more of hydrogen peroxide, carbamide peroxide and sodium chlorite;
the desensitizer is one or more of casein phosphopeptide-amorphous calcium phosphate, casein phosphopeptide-amorphous calcium fluorophosphate, sodium fluoride, potassium fluoride, sodium monofluorophosphate, potassium monofluorophosphate, amorphous calcium phosphate, sodium calcium phosphosilicate, potassium calcium phosphosilicate, potassium nitrate, dipotassium glycyrrhizinate and potassium chloride;
preferably, the whitening and desensitizing agents are used in the dental care portion in an amount of 3-6wt.% and 3-10wt.%, respectively.
When the whitening agent and the desensitizing agent are added to the tooth care part in the mode, the whitening effect and the desensitizing effect on teeth can be better considered, and the blocking effect of the transition part is not influenced.
Preferably, the gum care portion contains a care agent;
the nursing agent is one or more of vitamin C and its derivatives, vitamin E and its derivatives, hyaluronic acid, hyaluronate, allantoin and bisabolol;
preferably, the amount of the conditioning agent in the gum care portion is 0.2-5wt.%.
When the gum nursing part is added with the nursing agent in the mode, the gum nursing effect is better, and the blocking effect of the transition part is not influenced.
Preferably, the tooth care part, the gum care part and the transition part all contain a gelling agent;
the gel forming agent is one or more of polyvinylpyrrolidone, xanthan gum, shellac, carrageenan, guar gum, gelatin, konjac gum and cellulose;
preferably, the conditioning agent is used in each part in an amount of 2.5-5wt.%.
When the invention is carried out by matching with the gel forming agent, the tooth care part, the gum care part and the transition part can play respective functions stably.
Preferably, the tooth care portion, the gum care portion and the transition portion each contain a humectant;
the humectant is one or more of glycerol, ethanol, propylene glycol, octanediol and sorbitol;
preferably, the humectant is present in an amount of 30-50wt.% in each part.
Preferably, the tooth care portion, the gum care portion and the transition portion each contain a ph adjuster;
the ph regulator is one or more of sodium carbonate, sodium bicarbonate, sodium hydroxide, potassium hydroxide, citric acid, zinc citrate, potassium citrate, sodium phosphate, sodium dihydrogen phosphate, disodium hydrogen phosphate, potassium dihydrogen phosphate and dipotassium hydrogen phosphate;
preferably, the ph modifier is used in each fraction in an amount of 0.1-1wt.%.
Preferably, the tooth care part, the gum care part and the transition part all contain sweetener and/or essence;
the sweetener is one or a combination of more of sucralose, saccharin sodium, stevioside, xylitol, aspartame, acesulfame potassium and thaumatin;
the essence is oil-soluble essence or water-soluble essence;
preferably, the sweetener is used in an amount of 0.1 to 0.5wt.% in each part and the flavour is used in an amount of 0.1 to 0.5wt.% in each part.
As a preferable scheme, when the specific selection and the dosage of the gelling agent, the humectant, the ph regulator, the sweetener and the essence in the tooth care part, the gum care part and the transition part are the same, the effect of each part is more beneficial.
The person skilled in the art can combine the above technical solutions according to common knowledge to obtain a preferred embodiment of the dental tape according to the invention.
As a preferred embodiment of the present invention, the dental care part consists of the following components: 3 to 6wt.% of whitening agent, 3 to 10wt.% of desensitizer, 2.5 to 5wt.% of gelling agent, 30 to 50wt.% of humectant, 0.1 to 1wt.% of ph regulator, 0.1 to 0.5wt.% of sweetener, 0.1 to 0.5wt.% of essence, and the balance being water.
The transition portion is composed of the following components: 1-5wt.% of nano titanium dioxide, 0.01-0.05wt.% of methylene blue, 2.5-5wt.% of gelling agent, 30-50wt.% of humectant, 0.1-1wt.% of ph regulator, 0.1-0.5wt.% of sweetener, 0.1-0.5wt.% of essence and the balance of water.
The gum care portion is composed of the following components: 0.2-5wt.% of care agent, 2.5-5wt.% of gelling agent, 30-50wt.% of humectant, 0.1-1wt.% of ph regulator, 0.1-0.5wt.% of sweetener, 0.1-0.5wt.% of essence, and the balance being water.
The invention further provides a preparation method of the dental paste, which comprises the following steps: and preparing the raw materials of the tooth care part, the transition part and the gum care part into gel by a vacuum emulsification method, and coating the gel on the support material in the re-region.
(III) beneficial effects
(1) The transition part in the dental paste can prevent the interpenetration between the tooth care part and the gum care part, can avoid the damage of the whitening component in the tooth care part to the gum, and can also prevent the uneven exertion of the efficacy (such as whitening effect) caused by the interpenetration of the two parts.
(2) The tooth care part and the gum care part in the tooth paste can exert good care effects, and can better protect teeth and gums. Wherein the tooth care portion can prevent the occurrence of a tooth allergy while achieving a whitening effect.
Detailed Description
The following examples are illustrative of the invention and are not intended to limit the scope of the invention.
The specific techniques or conditions are not identified in the examples and are described in the literature in this field or are carried out in accordance with the product specifications. The reagents or equipment used were conventional products available for purchase by regular vendors without the manufacturer's attention.
Example 1
The present embodiment first provides a dental patch comprising a PET film and a gel comprising: a tooth care portion, a gum care portion, and a transition portion;
the transition portion is used for separating the tooth care portion and the gum care portion, and the volume ratio of the tooth care portion to the transition portion to the gum care portion is 1:0.2:1.
(1) The tooth care portion is composed of:
water: allowance of
Sweetener: 0.1wt.%
ph regulator: 0.2wt.%
Humectant: 30wt.%
Whitening agent: 3wt.%
Desensitizing agent: 3wt.%
Sizing agent: 3wt.%
Essence: 0.1wt.%.
Wherein the sweetener is aspartame, the ph regulator is sodium bicarbonate, the humectant is glycerin, the whitening agent is hydrogen peroxide, the desensitizing agent is potassium nitrate, the gelling agent is xanthan gum, and the essence is water-soluble peppermint essence.
(2) The transition part is formed by:
water: allowance of
Sweetener: 0.1wt.%
ph regulator: 0.2wt.%
Humectant: 30wt.%
Sizing agent: 3wt.%
Essence: 0.1wt.%
Methylene blue: 0.01wt.%
Nano titanium dioxide: 1wt.%.
Wherein the sweetener is aspartame, the ph regulator is sodium bicarbonate, the humectant is glycerin, the gelling agent is xanthan gum, and the essence is water-soluble peppermint essence.
(3) The gum nursing part is composed of:
water: allowance of
Sweetener: 0.1wt.%
ph regulator: 0.2wt.%
Humectant: 30wt.%
Sizing agent: 3wt.%
Nursing agent: 0.2wt.%
Essence: 0.1wt.%.
Wherein the sweetener is aspartame, the ph regulator is sodium bicarbonate, the humectant is glycerin, the gelling agent is xanthan gum, the nursing agent is allantoin, and the essence is water-soluble peppermint essence.
The embodiment further provides a preparation method of the dental tape, which specifically comprises the following steps: the tooth whitening desensitization part, the transition part and the gum care part are respectively prepared into gel by a vacuum emulsification method, and then coated on the PET film according to the proportion of 1:0.2:1, thus obtaining the tooth whitening desensitization gel.
Example 2
The present embodiment first provides a dental patch comprising a PET film and a gel comprising: a tooth care portion, a gum care portion, and a transition portion;
the transition portion is used for separating the tooth care portion and the gum care portion, and the volume ratio of the tooth care portion to the transition portion to the gum care portion is 1:0.4:1.
(1) The tooth care portion is composed of:
water: allowance of
Sweetener: 0.2wt.%
ph regulator: 0.1wt.%
Humectant: 40wt.%
Whitening agent: 3.5wt.%
Desensitizing agent: 5wt.%
Sizing agent: 5wt.%
Essence: 0.2wt.%.
Wherein the sweetener is steviosin, the ph regulator is sodium dihydrogen phosphate, the humectant is glycerin, the whitening agent is carbamide peroxide, the desensitizing agent is dipotassium glycyrrhizinate, the gelling agent is polyvinylpyrrolidone, and the essence is water-soluble lemon essence.
(2) The transition part is formed by:
water: allowance of
Sweetener: 0.2wt.%
ph regulator: 0.1wt.%
Humectant: 40wt.%
Sizing agent: 5wt.%
Essence: 0.2wt.%
Methylene blue: 0.02wt.%
Nano titanium dioxide: 2wt.%.
Wherein the sweetener is steviosin, the ph regulator is sodium dihydrogen phosphate, the humectant is glycerin, the gelling agent is polyvinylpyrrolidone, and the essence is water-soluble lemon essence.
(3) The gum nursing part is composed of:
water: allowance of
Sweetener: 0.2wt.%
ph regulator: 0.1wt.%
Humectant: 40wt.%
Sizing agent: 5wt.%
Nursing agent: 1wt.%
Essence: 0.2wt.%.
Wherein the sweetener is steviosin, the ph regulator is sodium dihydrogen phosphate, the humectant is glycerin, the gelling agent is polyvinylpyrrolidone, the nursing agent is bisabolol, and the essence is water-soluble lemon essence.
The embodiment further provides a preparation method of the dental tape, which specifically comprises the following steps: the tooth whitening desensitization part, the transition part and the gum care part are respectively prepared into gel by a vacuum emulsification method, and then coated on the PET film according to the proportion of 1:0.4:1, thus obtaining the tooth whitening desensitization gel.
Example 3
The present embodiment first provides a dental patch comprising a PET film and a gel comprising: a tooth care portion, a gum care portion, and a transition portion;
the transition portion is used for separating the tooth care portion and the gum care portion, and the volume ratio of the tooth care portion to the transition portion to the gum care portion is 1:0.5:1.
(1) The tooth care portion is composed of:
water: allowance of
Sweetener: 0.5wt.%
ph regulator: 1wt.%
Humectant: 50wt.%
Whitening agent: 6wt.%
Desensitizing agent: 10wt.%
Sizing agent: 2.5wt.%
Essence: 0.5wt.%.
Wherein the sweetener is xylitol, the ph regulator is disodium hydrogen phosphate, the humectant is glycerin, the whitening agent is sodium chlorite, the desensitizer is potassium chloride, the gelling agent is polyvinylpyrrolidone and cellulose which are mixed according to the mass ratio of 1:1, and the essence is oil-soluble sakura essence.
(2) The transition part is formed by:
water: allowance of
Sweetener: 0.5wt.%
ph regulator: 1wt.%
Humectant: 50wt.%
Sizing agent: 2.5wt.%
Essence: 0.5wt.%
Methylene blue: 0.01wt.%
Nano titanium dioxide: 5wt.%.
Wherein the sweetener is xylitol, the ph regulator is disodium hydrogen phosphate, the humectant is glycerin, the gelling agent is polyvinylpyrrolidone and cellulose which are mixed according to the mass ratio of 1:1, and the essence is oil-soluble sakura essence.
(3) The gum nursing part is composed of:
water: allowance of
Sweetener: 0.5wt.%
ph regulator: 1wt.%
Humectant: 50wt.%
Sizing agent: 2.5wt.%
Nursing agent: 5wt.%
Essence: 0.5wt.%.
Wherein the sweetener is xylitol, the ph regulator is disodium hydrogen phosphate, the humectant is glycerin, the gelling agent is polyvinylpyrrolidone and cellulose which are mixed according to the mass ratio of 1:1, the nursing agent is vitamin C sodium phosphate, and the essence is oil-soluble sakura essence.
The embodiment further provides a preparation method of the dental tape, which specifically comprises the following steps: the tooth whitening desensitization part, the transition part and the gum care part are respectively prepared into gel by a vacuum emulsification method, and then coated on the PET film according to the proportion of 1:0.5:1, thus obtaining the tooth whitening desensitization gel.
Comparative example 1
This comparative example provides a dental patch which differs from example 1 only in that: the transition part does not contain nano titanium dioxide.
Test examples
1. After the preparation, all samples were hermetically stored in an incubator at 50℃for one month, and the penetration of the dental patches of examples and comparative examples was observed, and the results are shown in Table 1 below.
TABLE 1
2. The whitening effect of the tooth paste of the example was measured, and the experimental method was as follows:
40 subjects, 19 men, 21 women, 18-50 years of age, physical health, at least eight natural incisors, extrinsic staining of teeth, no intrinsic staining of teeth, no oral disease and no hypoplasia of enamel, no history of related drug allergy, female subjects non-gestational or lactating.
Subjects were randomized into 4 groups of 10 cases each. The 4 groups of subjects used the dental patches prepared in example 1, example 2, example 3, and comparative example 1, respectively. The subjects used the dental tape for 1 hour per day for 14 consecutive days. During the test period, teeth were brushed normally daily using the same toothpaste and tooth color numbers were checked on day 0 and day 15.
The front-back comparison of the test subjects is adopted, and the VITA Toothguide3D-Master tooth color comparison plate which is common at home and abroad is used as a standard, so that the upper left middle incisors of the test subjects are selected and the upper middle incisors are used for tooth color examination.
Evaluation criteria: subjects underwent dental nasal obstruction with 3 significant increases in chromaticity at day 0 and day 15, 1-2 chromaticities being effective, no increase in chromaticity or no decrease in chromaticity. The effective rate=effective number/number of subjects 100%, the effective rate= (effective number+effective number)/number of subjects 100%, and the results are shown in table 2 below.
TABLE 2
| Test group | Obvious efficiency (%) | Effective rate (%) |
| Example 1 | 80 | 100 |
| Example 2 | 90 | 100 |
| Example 3 | 80 | 100 |
From the results, the dental patch of the present invention has excellent teeth whitening ability.
3. The gum care efficacy of the example and comparative patches was measured and shown to further protect the gums from the irritation of the patch by:
subjects 40, 20 men, 20 women, and ages 18-40. All subjects were healthy in physical condition. There was no history of related drug allergy, and the female subjects were non-pregnant or lactating.
Subjects were randomized into 4 groups of 10 cases each. The 4 groups of subjects used the dental patches prepared in example 1, example 2, example 3, and comparative example 1, respectively. The subject used the dental tape for one hour, and after waiting for 30 minutes, the subject was asked whether the subject had gum discomfort or abnormal sensation. The presence of discomfort or abnormal sensation is marked as a irritation to the gums. Gum irritation rate = number of gum irritation/number of subjects tested. The results are shown in Table 3 below.
TABLE 3 Table 3
| Test group | Gum irritation ratio (%) |
| Example 1 | 0 |
| Example 2 | 0 |
| Example 3 | 0 |
| Comparative example 1 | 30 |
From the results, the dental tape of the present invention has good gum care ability.
4. The desensitizing ability of the dental tape of the examples was measured as follows:
subjects 40, 20 men, 20 women, and ages 18-40. All subjects had dentinal hypersensitivity and other physical conditions were healthy. There was no history of related drug allergy, and the female subjects were non-pregnant or lactating.
Subjects were randomized into 4 groups of 10 cases each. Sensitivity (i.e., pain class) was recorded by blowing cold air vertically for 1s 5mm from the buccal surface of the sensitive teeth of the subject. The subject was allowed to evaluate the tooth sensitivity of the subject by using the dental tape prepared in example 1, example 2, example 3, and comparative example 1 for one hour, using a method of vertically blowing cold air, and the subject recorded the sensitivity after the teeth were stimulated.
Sensitivity evaluation criteria: according to the evaluation criteria of shichuan two, 3 degrees is stimulation may induce intolerable pain, 2 degrees is stimulation may induce significant pain, but may be tolerated, 1 degree is stimulation may induce pain that is mild or inadaptation, and 0 degree is cold or mechanical stimulus pain.
Efficacy assessment criteria: the "significant effect" is that the difference between the sensitivity before and after use is not less than 2, the "effective" is that the difference between the sensitivity before and after use is 1, the "ineffective" is that the difference between the sensitivity before and after treatment is 0, and the "deteriorated" is that the difference between the sensitivity before and after treatment is negative.
Wherein, the effective rate=effective number/tested person number is 100%, and the effective rate=effective person number/tested person number is 100%. The results are shown in Table 4 below.
TABLE 4 Table 4
| Test group | Obvious efficiency (%) | Effective rate (%) |
| Example 1 | 70 | 100 |
| Example 2 | 90 | 100 |
| Example 3 | 80 | 100 |
From the results, the dental tape of the present invention has good tooth desensitizing ability.
While the invention has been described in detail in the foregoing general description and with reference to specific embodiments thereof, it will be apparent to one skilled in the art that modifications and improvements can be made thereto. Accordingly, such modifications or improvements may be made without departing from the spirit of the invention and are intended to be within the scope of the invention as claimed.
Claims (18)
1. A dental patch comprising a support material and a gel, wherein the gel comprises: a tooth care portion, a gum care portion, and a transition portion;
wherein the transition portion is for separating the tooth care portion and the gum care portion, and comprises 1-5wt.% nano-titanium dioxide;
the transition portion further comprises a pigment that can interact with components in the tooth care portion and/or the gum care portion and undergo a color change; the pigment is methylene blue, and the dosage of the pigment in the transition part is 0.01-0.05wt.%;
the volume ratio of the tooth care part to the transition part to the gum care part is 1 (0.2-0.5) (0.8-1.2);
the preparation method of the dental paste comprises the following steps: and preparing the raw materials of the tooth care part, the transition part and the gum care part into gel by a vacuum emulsification method, and coating the gel on the support material in the re-region.
2. The dental patch of claim 1, wherein the dental care portion comprises a whitening agent and a desensitizing agent;
the whitening agent is one or a combination of more of hydrogen peroxide, carbamide peroxide and sodium chlorite;
the desensitizer is one or more of casein phosphopeptide-amorphous calcium phosphate, casein phosphopeptide-amorphous calcium fluorophosphate, sodium fluoride, potassium fluoride, sodium monofluorophosphate, potassium monofluorophosphate, amorphous calcium phosphate, sodium calcium phosphosilicate, potassium calcium phosphosilicate, potassium nitrate, dipotassium glycyrrhizinate and potassium chloride.
3. The dental paste of claim 2, wherein the whitening and desensitizing agents are used in the dental care portion in an amount of 3-6wt.% and 3-10wt.%, respectively.
4. The dental patch of any one of claims 1-3, wherein the gum care portion contains a care agent;
the caring agent is one or more of vitamin C and its derivatives, vitamin E and its derivatives, hyaluronic acid, hyaluronate, allantoin, and bisabolol.
5. The dental patch of claim 4, wherein the amount of said treatment agent in the gum care portion is 0.2-5wt.%.
6. The dental patch of any one of claims 1-3, 5, wherein the tooth care portion, gum care portion, and transition portion each comprise a gel forming agent;
the gel forming agent is one or more of polyvinylpyrrolidone, xanthan gum, shellac, carrageenan, guar gum, gelatin, konjac gum and cellulose.
7. The dental paste of claim 4, wherein the tooth care portion, gum care portion, and transition portion each comprise a gel forming agent;
the gel forming agent is one or more of polyvinylpyrrolidone, xanthan gum, shellac, carrageenan, guar gum, gelatin, konjac gum and cellulose.
8. The dental paste of claim 6, wherein the gel forming agent is present in the respective portion in an amount of 2.5 to 5wt.%.
9. The dental patch of any one of claims 1-3, 5, 7-8, wherein the tooth care portion, gum care portion, and transition portion each comprise a humectant;
the humectant is one or more of glycerol, ethanol, propylene glycol, octanediol and sorbitol.
10. The dental patch of claim 4, wherein the tooth care portion, gum care portion, and transition portion each comprise a humectant;
the humectant is one or more of glycerol, ethanol, propylene glycol, octanediol and sorbitol.
11. The dental patch of claim 9, wherein the humectant is present in an amount of 30-50wt.% in each portion.
12. The dental patch of any one of claims 1-3, 5, 7-8, 10-11, wherein the dental care portion, the gingival care portion, and the transition portion each include a ph adjuster;
the ph regulator is one or more of sodium carbonate, sodium bicarbonate, sodium hydroxide, potassium hydroxide, citric acid, zinc citrate, potassium citrate, sodium phosphate, sodium dihydrogen phosphate, disodium hydrogen phosphate, potassium dihydrogen phosphate and dipotassium hydrogen phosphate.
13. The dental patch of claim 4, wherein the tooth care portion, gum care portion, and transition portion each include a ph adjuster;
the ph regulator is one or more of sodium carbonate, sodium bicarbonate, sodium hydroxide, potassium hydroxide, citric acid, zinc citrate, potassium citrate, sodium phosphate, sodium dihydrogen phosphate, disodium hydrogen phosphate, potassium dihydrogen phosphate and dipotassium hydrogen phosphate.
14. The dental patch of claim 12, wherein the ph modifier is present in each portion in an amount of 0.1 to 1wt.%.
15. The dental patch of any one of claims 1-3, 5, 7-8, 10-11, 13-14, wherein the dental care portion, gum care portion, and transition portion each comprise a sweetener and/or a flavoring;
the sweetener is one or a combination of more of sucralose, saccharin sodium, stevioside, xylitol, aspartame, acesulfame potassium and thaumatin;
the essence is oil-soluble essence or water-soluble essence.
16. The dental patch of claim 4, wherein the tooth care portion, gum care portion, and transition portion each comprise a sweetener and/or a flavoring;
the sweetener is one or a combination of more of sucralose, saccharin sodium, stevioside, xylitol, aspartame, acesulfame potassium and thaumatin;
the essence is oil-soluble essence or water-soluble essence.
17. The dental paste of claim 15, wherein the sweetener is present in an amount of 0.1-0.5wt.% in each portion and the flavoring is present in an amount of 0.1-0.5wt.% in each portion.
18. The method of preparing a dental patch according to any one of claims 1 to 17, comprising: and preparing the raw materials of the tooth care part, the transition part and the gum care part into gel by a vacuum emulsification method, and coating the gel on the support material in the re-region.
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| AU2017206470B2 (en) * | 2016-01-13 | 2022-08-18 | Lg Household & Health Care Ltd. | Preparation for oral cavity |
| CN105640787A (en) * | 2016-01-26 | 2016-06-08 | 浙江浙北药业有限公司 | Preparation method of tooth whitening strip |
| CN105616173A (en) * | 2016-01-26 | 2016-06-01 | 浙江浙北药业有限公司 | White strip and preparation method thereof |
| CN112107509B (en) * | 2020-09-25 | 2022-11-15 | 山东华熙海御生物医药有限公司 | Tooth whitening paste containing hyaluronic acid and preparation method thereof |
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| EP1837073A1 (en) * | 2006-03-24 | 2007-09-26 | L'oreal | Composite dyestuff of microcapsule type and cosmetic use thereof |
| KR20170073760A (en) * | 2015-12-18 | 2017-06-29 | (주) 바이오에스텍 | Dental Bleaching Composition and Dental Patch Comprising Titanium Dioxide, and Dental Bleaching Method Using This |
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