CN113429471B - 长效glp-1多肽类似物及其制备方法和应用 - Google Patents
长效glp-1多肽类似物及其制备方法和应用 Download PDFInfo
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Images
Classifications
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Engineering & Computer Science (AREA)
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- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (4)
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|---|---|---|---|
| CN202211555764.8A CN116554299A (zh) | 2021-07-19 | 2021-07-19 | 长效glp-1多肽类似物及其制备方法和应用 |
| CN202110815583.3A CN113429471B (zh) | 2021-07-19 | 2021-07-19 | 长效glp-1多肽类似物及其制备方法和应用 |
| CN202211555750.6A CN116410297A (zh) | 2021-07-19 | 2021-07-19 | 长效glp-1多肽类似物及其制备方法和应用 |
| PCT/CN2021/107770 WO2023000240A1 (fr) | 2021-07-19 | 2021-07-22 | Analogue de polypeptide glp-1 à action prolongée, son procédé de préparation et son utilisation |
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| CN202110815583.3A CN113429471B (zh) | 2021-07-19 | 2021-07-19 | 长效glp-1多肽类似物及其制备方法和应用 |
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| CN202211555750.6A Division CN116410297A (zh) | 2021-07-19 | 2021-07-19 | 长效glp-1多肽类似物及其制备方法和应用 |
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| CN202211555764.8A Pending CN116554299A (zh) | 2021-07-19 | 2021-07-19 | 长效glp-1多肽类似物及其制备方法和应用 |
| CN202110815583.3A Active CN113429471B (zh) | 2021-07-19 | 2021-07-19 | 长效glp-1多肽类似物及其制备方法和应用 |
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| CN202211555764.8A Pending CN116554299A (zh) | 2021-07-19 | 2021-07-19 | 长效glp-1多肽类似物及其制备方法和应用 |
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| CN (3) | CN116410297A (fr) |
| WO (1) | WO2023000240A1 (fr) |
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| CN114716533B (zh) * | 2022-04-12 | 2023-04-14 | 北京惠之衡生物科技有限公司 | 一种酰化的长效glp-1衍生物 |
| CN115947822B (zh) * | 2022-07-04 | 2023-08-18 | 北京惠之衡生物科技有限公司 | 一种长效酰化胰岛素衍生物及其药物组合物和应用 |
| CN117756913A (zh) * | 2022-11-07 | 2024-03-26 | 内蒙古博睿精创科技有限公司 | 一种新型长效多肽化合物、组合物及其应用 |
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| TWI362392B (en) * | 2005-03-18 | 2012-04-21 | Novo Nordisk As | Acylated glp-1 compounds |
| US8614182B2 (en) * | 2009-07-30 | 2013-12-24 | Jiangsu Hansoh Pharmaceuticals Co., Ltd. | GLP-1 analogues and their pharmaceutical salts and uses |
| CN103189389B (zh) * | 2011-09-03 | 2017-08-11 | 深圳市健元医药科技有限公司 | 新的glp‑ⅰ类似物及其制备方法和用途 |
| TWI700291B (zh) * | 2015-06-22 | 2020-08-01 | 美國禮來大藥廠 | 升糖素及glp-1共激動劑化合物 |
| CN111253475B (zh) * | 2020-02-18 | 2021-03-09 | 江苏诺泰澳赛诺生物制药股份有限公司 | Glp-1激动多肽化合物及其盐与合成方法及用途 |
| CN112110981B (zh) * | 2020-09-23 | 2021-06-25 | 深圳深创生物药业有限公司 | 一种包含长链脂肪二酸侧链的多肽的制备方法 |
| CN112898405B (zh) * | 2021-01-22 | 2023-02-28 | 深圳市图微安创科技开发有限公司 | 多肽化合物及其在预防或治疗糖尿病或糖尿病并发症中的应用 |
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2021
- 2021-07-19 CN CN202211555750.6A patent/CN116410297A/zh active Pending
- 2021-07-19 CN CN202211555764.8A patent/CN116554299A/zh active Pending
- 2021-07-19 CN CN202110815583.3A patent/CN113429471B/zh active Active
- 2021-07-22 WO PCT/CN2021/107770 patent/WO2023000240A1/fr unknown
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| Publication number | Publication date |
|---|---|
| CN113429471A (zh) | 2021-09-24 |
| CN116410297A (zh) | 2023-07-11 |
| CN116554299A (zh) | 2023-08-08 |
| WO2023000240A1 (fr) | 2023-01-26 |
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