CN113368325B - Resin intelligent purification system for blood perfusion device - Google Patents
Resin intelligent purification system for blood perfusion device Download PDFInfo
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- CN113368325B CN113368325B CN202110616644.3A CN202110616644A CN113368325B CN 113368325 B CN113368325 B CN 113368325B CN 202110616644 A CN202110616644 A CN 202110616644A CN 113368325 B CN113368325 B CN 113368325B
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- resin
- perfusion device
- device shell
- movable
- connecting shaft
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Analytical Chemistry (AREA)
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Abstract
The invention discloses a resin intelligent purification system for a blood perfusion device, which comprises a perfusion device shell, wherein an upper cover and a lower cover are respectively detachably connected at the upper end and the lower end of the perfusion device shell, a connecting shaft is arranged in the perfusion device shell, the upper end of the connecting shaft is connected with the upper cover, the connecting shaft rotates relative to the perfusion device shell, a plurality of movable resin plates are fixedly arranged on the periphery of the connecting shaft, a plurality of fixed resin plates are fixedly arranged on the inner wall of the perfusion device shell, the movable resin plates and the fixed resin plates are alternately arranged in the vertical direction, a plurality of resin adsorption areas are uniformly arranged on the movable resin plates and the fixed resin plates at intervals, and a resin adsorption plate is fixedly arranged at the bottom end in the perfusion device shell; through can produce relative pivoted setting between adapter sleeve and the movable cover in the upper cover, realized adjusting the relative angle between movable resin dish and the fixed resin dish according to the concentration of harmful substance in the blood, reasonable shortened the time of absorption, both guaranteed absorptive quality and improved absorptive efficiency.
Description
Technical Field
The invention relates to the technical field of medical equipment, in particular to an intelligent resin purification system for a blood perfusion device.
Background
The blood perfusion device is mainly applied to adsorption of molecular toxins in acute and chronic drug poisoning and uremia, and adsorption of pathogenic factors in liver diseases and immune fields. The patients with advanced renal failure need to sustain life by dialysis, small molecular substances in blood can be effectively removed through a dialysis membrane, but the detection result of modern medical means makes people recognize that more medium molecular weight substances (0.5-60 kDa) are key substances affecting the health of the patients, and the medium molecular weight substances are difficult to effectively remove by dialysis; in terms of maintaining the life of patients with renal failure, the effective removal of medium molecular substances, whether hemodialysis or hemodiafiltration is used, has become a new criterion for measuring whether a therapeutic method is effective.
The blood perfusion resin has the advantages of high specific surface area, strong adsorption performance, good mechanical strength, low organic residue, good blood compatibility and the like, and is suitable for various disease fields. The resin after coating is used as an effective broad-spectrum adsorbent and has wide clinical application. However, the resin adsorption purification device in the prior art mostly adopts a resin column or a resin net to adsorb blood, so that the contact time of the blood and a resin adsorption mechanism is shorter, the medium molecular substances in the blood can not be removed well, the adsorption effect can be greatly reduced, and toxic substances in the blood of uremic patients can not be effectively removed.
Disclosure of Invention
The invention aims to provide a resin intelligent purification system for a blood perfusion device, which aims to solve the problems in the background technology.
In order to achieve the above purpose, the present invention provides the following technical solutions: the utility model provides a resin intelligent purification system for blood perfusion device, wherein, including the perfusion device casing, the perfusion device casing is cylindric that medical grade plastics was made, both ends are dismantled respectively and are connected with upper cover and lower cover about the perfusion device casing, the inside connecting axle that is provided with of perfusion device casing, the upper end of connecting axle with the upper cover is connected, the connecting axle is relative the perfusion device casing rotates, the fixed a plurality of movable resin dishes that are provided with of periphery of connecting axle, fixed a plurality of fixed resin dishes that are provided with on the inner wall of perfusion device casing, movable resin dish, fixed resin dish alternate to set up in vertical direction, a plurality of resin adsorption areas that are evenly provided with on movable resin dish, the fixed resin dish alternate, the inside bottom fixed resin adsorption plate that is provided with of perfusion device casing.
Preferably, the upper cover comprises a connecting sleeve, a movable cover and a sealing ring, the connecting sleeve is detachably connected with the perfusion device shell, the movable cover is arranged at the upper end of the connecting sleeve, the sealing ring is arranged between the connecting sleeve and the movable cover, and the connecting shaft is fixedly connected with the movable cover.
Preferably, the inner wall of the connecting sleeve is provided with an internal thread, the outer wall of the upper end of the perfusion device shell is provided with an external thread, and the connecting sleeve is detachably connected to the upper end of the perfusion device shell through threaded connection.
Preferably, the center of the fixed resin disk is provided with an avoidance hole for the connecting shaft to pass through.
Preferably, the material of the perfusion device shell is Polycarbonate (PC), polytetrafluoroethylene (PTFE) or Polyamide (PA).
Preferably, the resin used in the resin adsorption areas of the movable resin tray and the fixed resin tray is ion exchange resin or adsorption resin.
Preferably, the movable resin tray and the fixed resin tray comprise or L stainless steel support frames.
The beneficial effects are that: compared with the prior art, the invention has the beneficial effects that: through the arrangement of the movable resin disk and the fixed resin disk, the blood is filtered by a plurality of resin adsorption areas arranged in the vertical direction, so that the contact time and the contact area of the blood and the resin are improved, harmful substances in the blood are removed well, and the quality and the efficiency of blood purification are improved greatly; through can produce relative pivoted setting between adapter sleeve and the movable cover in the upper cover, realized adjusting the relative angle between movable resin dish and the fixed resin dish according to the concentration of harmful substance in the blood, reasonable shortened the time of absorption, both guaranteed absorptive quality and improved absorptive efficiency.
Drawings
Fig. 1 is a schematic diagram of the overall structure of an intelligent purification system for a blood perfusion device according to the present invention.
Fig. 2 is a schematic view of a specific structure of the upper cover.
Fig. 3 is a schematic structural view of the movable resin tray.
Fig. 4 is a schematic structural view of the fixed resin disk.
In the accompanying drawings: 1-perfusion device shell, 2-upper cover, 201-adapter sleeve, 202-movable cover, 203-sealing ring, 3-lower cover, 4-connecting axle, 5-movable resin disk, 6-fixed resin disk, 7-resin adsorption plate, 8-resin adsorption area, 9-avoidance hole.
Detailed Description
In order that the above objects, features and advantages of the invention will be more clearly understood, a further description of the invention will be rendered by reference to the appended drawings and examples. It should be noted that, in the case of no conflict, the embodiments of the present application and the features in the embodiments may be combined with each other.
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention, however, the present invention may be practiced otherwise than as described herein, and therefore the present invention is not limited to the specific embodiments of the disclosure that follow.
Examples
Referring to the drawings, in the embodiment of the invention, a resin intelligent purification system for a blood perfusion apparatus comprises a perfusion apparatus housing 1, wherein the perfusion apparatus housing 1 is cylindrical made of medical grade plastic, an upper cover 2 and a lower cover 3 are detachably connected to the upper end and the lower end of the perfusion apparatus housing 1 respectively, a connecting shaft 4 is arranged inside the perfusion apparatus housing 1, the upper end of the connecting shaft 4 is connected with the upper cover 2, the connecting shaft 4 rotates relative to the perfusion apparatus housing 1, a plurality of movable resin plates 5 are fixedly arranged on the periphery of the connecting shaft 4, a plurality of fixed resin plates 6 are fixedly arranged on the inner wall of the perfusion apparatus housing 1, the movable resin plates 5 and the fixed resin plates 6 are alternately arranged in the vertical direction, a plurality of resin adsorption areas 8 are uniformly arranged on the movable resin plates 5 and the fixed resin plates 6 alternately, and a resin adsorption plate 7 is fixedly arranged at the bottom end inside the perfusion apparatus housing 1.
Further, the upper cover 2 includes a connecting sleeve 201, a movable cover 202 and a sealing ring 203, the connecting sleeve 201 is detachably connected with the perfusion apparatus housing 1, the movable cover 202 is disposed at the upper end of the connecting sleeve 201, the sealing ring 203 is disposed between the connecting sleeve 201 and the movable cover 202, and the connecting shaft 4 is fixedly connected with the movable cover 202.
Further, an inner wall of the connecting sleeve 201 is provided with an internal thread, an outer wall of the upper end of the perfusion apparatus housing 1 is provided with an external thread, and the connecting sleeve 201 is detachably connected to the upper end of the perfusion apparatus housing 1 through threaded connection.
Further, a relief hole 9 through which the connecting shaft 4 passes is formed in the center of the fixed resin plate 6.
Further, the material of the perfusion apparatus housing 1 is Polycarbonate (PC), polytetrafluoroethylene (PTFE) or Polyamide (PA).
Further, the resin used in the resin adsorption areas 8 of the movable resin tray 5 and the fixed resin tray 6 is ion exchange resin or adsorption resin.
Further, the movable resin tray 5 and the fixed resin tray 6 each comprise a 316 or 317L stainless steel support frame.
The using process comprises the following steps:
when in use, blood enters from the upper end of the perfusion device and flows out after being adsorbed from the lower end, the movable cover 202 is turned to adjust the relative angle between the movable resin disk 5 and the fixed resin disk 6 according to the concentration of harmful substances, the overlapping area of the resin adsorption areas 8 on the movable resin disk 5 and the fixed resin disk 6 is changed, the adsorption quality and the efficiency are both considered, and the practicability of the perfusion device is enhanced.
In the process, through the arrangement of the movable resin disc and the fixed resin disc, the blood is filtered by the resin adsorption areas arranged in the vertical directions, so that the contact time and the contact area of the blood and the resin are improved, harmful substances in the blood are better removed, and the quality and the efficiency of blood purification are greatly improved; the relative rotation between the connecting sleeve in the upper cover and the movable cover can be realized, so that the relative angle between the movable resin disc and the fixed resin disc is adjusted according to the concentration of harmful substances in blood, the adsorption time is reasonably shortened, the adsorption quality is ensured, and the adsorption efficiency is improved; the utility model has the advantages of this application simple structure, the practicality is strong, and easy operation is worth promoting.
The foregoing is merely a preferred embodiment of the present invention, and it should be noted that modifications and improvements can be made by those skilled in the art without departing from the spirit of the present invention, and these should also be considered as the scope of the present invention, which does not affect the effect of the implementation of the present invention and the utility of the patent.
In the description of the present invention, it should be understood that the terms "orientation" or "positional relationship" are based on the orientation or positional relationship shown in the drawings, and are merely for convenience of description and to simplify the description, rather than to indicate or imply that the apparatus or elements referred to must have a particular orientation, be constructed and operate in a particular orientation, and therefore should not be construed as limiting the invention.
In the present invention, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communicated with the inside of two elements or the interaction relationship of the two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art according to the specific circumstances.
Claims (4)
1. An intelligent purification system of resin for a blood perfusion device is characterized in that: the perfusion device comprises a perfusion device shell (1), wherein the perfusion device shell (1) is cylindrical made of medical grade plastic, an upper cover (2) and a lower cover (3) are respectively detachably connected to the upper end and the lower end of the perfusion device shell (1), a connecting shaft (4) is arranged inside the perfusion device shell (1), the upper end of the connecting shaft (4) is connected with the upper cover (2), the connecting shaft (4) rotates relative to the perfusion device shell (1), a plurality of movable resin discs (5) are fixedly arranged on the periphery of the connecting shaft (4), a plurality of fixed resin discs (6) are fixedly arranged on the inner wall of the perfusion device shell (1), a plurality of resin adsorption areas (8) are uniformly arranged on the movable resin discs (5) and the fixed resin discs (6) in a mutual mode, a dodging hole (9) for the connecting shaft (4) to pass through is formed in the center of the fixed resin discs (6), and a perfusion plate (7) is fixedly arranged at the bottom end of the perfusion device shell (1);
the upper cover (2) comprises a connecting sleeve (201), a movable cover (202) and a sealing ring (203), wherein the connecting sleeve (201) is detachably connected with the perfusion device shell (1), the movable cover (202) is arranged at the upper end of the connecting sleeve (201), the sealing ring (203) is arranged between the connecting sleeve (201) and the movable cover (202), the connecting shaft (4) is fixedly connected with the movable cover (202), the inner wall of the connecting sleeve (201) is provided with an internal thread, the outer wall of the upper end of the perfusion device shell (1) is provided with an external thread, and the connecting sleeve (201) is detachably connected with the upper end of the perfusion device shell (1) through a threaded connection.
2. The intelligent purification system for a resin for a blood perfusion apparatus according to claim 1, wherein: the perfusion device shell (1) is made of Polycarbonate (PC), polytetrafluoroethylene (PTFE) or Polyamide (PA).
3. The intelligent purification system for a resin for a blood perfusion apparatus according to claim 1, wherein: the resin used in the resin adsorption areas (8) of the movable resin disk (5) and the fixed resin disk (6) is ion exchange resin or adsorption resin.
4. The intelligent purification system for a resin for a blood perfusion apparatus according to claim 1, wherein: the movable resin disc (5) and the fixed resin disc (6) comprise support frames made of 316 or 317L stainless steel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110616644.3A CN113368325B (en) | 2021-05-27 | 2021-05-27 | Resin intelligent purification system for blood perfusion device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110616644.3A CN113368325B (en) | 2021-05-27 | 2021-05-27 | Resin intelligent purification system for blood perfusion device |
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| Publication Number | Publication Date |
|---|---|
| CN113368325A CN113368325A (en) | 2021-09-10 |
| CN113368325B true CN113368325B (en) | 2023-08-01 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202110616644.3A Active CN113368325B (en) | 2021-05-27 | 2021-05-27 | Resin intelligent purification system for blood perfusion device |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112999694A (en) * | 2021-03-24 | 2021-06-22 | 沧州信联化工有限公司 | Raw material refining device for processing tetramethylammonium hydroxide and use method thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06277467A (en) * | 1993-03-29 | 1994-10-04 | Toto Ltd | Rotary flat membrane filter machine |
| JP2011019685A (en) * | 2009-07-15 | 2011-02-03 | Nikkiso Co Ltd | Hemocatharsis column |
| CN204618991U (en) * | 2014-11-03 | 2015-09-09 | 珠海健帆生物科技股份有限公司 | A kind of blood perfusion device |
| CN204293593U (en) * | 2014-11-03 | 2015-04-29 | 珠海健帆生物科技股份有限公司 | A kind of blood perfusion device |
| CN204428504U (en) * | 2014-12-27 | 2015-07-01 | 珠海健帆生物科技股份有限公司 | A kind of perfusion device drainage stent and perfusion device |
| EP3347120A4 (en) * | 2015-09-11 | 2019-08-28 | Ultra Small Fibers, LLC | Tunable nanofiber filter media and filter devices |
| CN209864812U (en) * | 2019-03-19 | 2019-12-31 | 北京中科盛康科技有限公司 | Blood perfusion device |
| CN111957304B (en) * | 2020-08-19 | 2021-02-26 | 上海金成高分子材料有限公司 | Macroporous adsorption resin for blood perfusion and preparation method thereof |
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