CN113368325A - Intelligent resin purification system for blood perfusion device - Google Patents
Intelligent resin purification system for blood perfusion device Download PDFInfo
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- CN113368325A CN113368325A CN202110616644.3A CN202110616644A CN113368325A CN 113368325 A CN113368325 A CN 113368325A CN 202110616644 A CN202110616644 A CN 202110616644A CN 113368325 A CN113368325 A CN 113368325A
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- resin
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- perfusion device
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
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- Public Health (AREA)
- Urology & Nephrology (AREA)
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Abstract
The invention discloses a resin intelligent purification system for a blood perfusion apparatus, which comprises a perfusion apparatus shell, wherein the upper end and the lower end of the perfusion apparatus shell are respectively detachably connected with an upper cover and a lower cover, a connecting shaft is arranged in the perfusion apparatus shell, the upper end of the connecting shaft is connected with the upper cover, the connecting shaft rotates relative to the perfusion apparatus shell, a plurality of movable resin discs are fixedly arranged on the periphery of the connecting shaft, a plurality of fixed resin discs are fixedly arranged on the inner wall of the perfusion apparatus shell, the movable resin discs and the fixed resin discs are arranged in the vertical direction at intervals, a plurality of resin adsorption areas are uniformly arranged on the movable resin discs and the fixed resin discs at intervals, and a resin adsorption plate is fixedly arranged at the bottom end in the perfusion apparatus shell; through the setting that can produce relative pivoted between adapter sleeve and the movable cover in the upper cover, realized adjusting the relative angle between movable resin dish and the fixed resin dish according to harmful substance's in the blood concentration, the reasonable time that has shortened the absorption, both guaranteed the absorbent quality and improved absorbent efficiency again.
Description
Technical Field
The invention relates to the technical field of medical equipment, in particular to an intelligent resin purification system for a hemoperfusion apparatus.
Background
The hemoperfusion apparatus is mainly used for molecular toxin adsorption in acute and chronic drug poisoning and uremia, and adsorption of pathogenic factors in the fields of liver disease and immunity. The patient with late renal failure needs dialysis to maintain life, and small molecular substances in blood can be effectively removed through a dialysis membrane, but the detection result of modern medical means leads people to realize that more medium molecular weight substances (0.5-60 kDa) are key substances affecting the health of the patient, and the medium molecular weight substances are difficult to effectively remove through dialysis; in the aspect of maintaining the life of a renal failure patient, no matter hemodialysis or hemoperfusion is adopted, the effective removal of medium molecular substances becomes a new judgment standard for judging whether a treatment method is effective or not.
The hemoperfusion resin has the advantages of high specific surface area, strong adsorption performance, good mechanical strength, low organic residue, good blood compatibility and the like, and is suitable for the field of various diseases. The resin after being coated is used as an effective broad-spectrum adsorbent and is widely applied clinically. However, the resin adsorption purification device in the prior art mostly adopts a resin column or a resin net to adsorb blood, so that the contact time between the blood and the resin adsorption mechanism is short, the medium molecular substances in the blood cannot be well removed, the adsorption effect is greatly reduced, and toxic substances in the blood of uremia patients cannot be effectively removed.
Disclosure of Invention
The invention aims to provide an intelligent resin purification system for a hemoperfusion apparatus, which aims to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: the utility model provides a blood perfusion ware is with resin intelligence clean system, wherein, includes perfusion ware casing, perfusion ware casing is the cylindric that medical grade plastics were made, both ends can be dismantled respectively about the perfusion ware casing and be connected with upper cover and lower cover, perfusion ware casing inside is provided with the connecting axle, the upper end of connecting axle with the upper cover is connected, the connecting axle is relative perfusion ware casing rotates, the fixed a plurality of movable resin dish that is provided with in periphery of connecting axle, the fixed a plurality of fixed resin dish that is provided with on the inner wall of perfusion ware casing, movable resin dish, fixed resin dish set up in vertical direction within a definite time, movable resin dish, fixed resin dish are gone up and are evenly be provided with a plurality of resin adsorption zones within a definite time, perfusion ware casing inside bottom mounting is provided with the resin adsorption board.
Preferably, the upper cover includes adapter sleeve, movable cover and sealing washer, the adapter sleeve with perfusion device casing detachable connects, the movable cover sets up the upper end of adapter sleeve, be provided with the sealing washer between adapter sleeve, the movable cover, the connecting axle with movable cover fixed connection.
Preferably, the inner wall of the connecting sleeve is provided with an internal thread, the outer wall of the upper end of the casing of the perfusion device is provided with an external thread, and the connecting sleeve is detachably connected to the upper end of the casing of the perfusion device through a threaded connection.
Preferably, the center of the fixed resin disc is provided with an avoidance hole for the connecting shaft to pass through.
Preferably, the material of the perfusion device shell is Polycarbonate (PC), Polytetrafluoroethylene (PTFE) or Polyamide (PA).
Preferably, the resin used in the resin adsorption zone of the movable resin tray and the fixed resin tray is ion exchange resin or adsorption resin.
Preferably, the movable resin tray and the fixed resin tray both comprise a support frame made of or L stainless steel.
Has the advantages that: compared with the prior art, the invention has the beneficial effects that: through the arrangement of the movable resin disc and the fixed resin disc, blood is filtered by the resin adsorption areas arranged in the vertical direction, so that the contact time and area between the blood and the resin are improved, harmful substances in the blood are better removed, and the quality and efficiency of blood purification are greatly improved; through the setting that can produce relative pivoted between adapter sleeve and the movable cover in the upper cover, realized adjusting the relative angle between movable resin dish and the fixed resin dish according to harmful substance's in the blood concentration, the reasonable time that has shortened the absorption, both guaranteed the absorbent quality and improved absorbent efficiency again.
Drawings
Fig. 1 is a schematic diagram of the overall structure of an intelligent resin purification system for a hemoperfusion apparatus according to the present invention.
Fig. 2 is a schematic diagram of the specific structure of the upper cover.
Fig. 3 is a schematic view of the structure of a movable resin tray.
Fig. 4 is a schematic structural view of a fixed resin tray.
In the drawings: 1-perfusion device shell, 2-upper cover, 201-connecting sleeve, 202-movable cover, 203-sealing ring, 3-lower cover, 4-connecting shaft, 5-movable resin disc, 6-fixed resin disc, 7-resin adsorption plate, 8-resin adsorption area and 9-avoiding hole.
Detailed Description
In order that the above objects, features and advantages of the present invention can be more clearly understood, the present invention will be further described with reference to the accompanying drawings and examples. It should be noted that the embodiments and features of the embodiments of the present application may be combined with each other without conflict.
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention, however, the present invention may be practiced in other ways than those specifically described herein, and thus the present invention is not limited to the specific embodiments of the present disclosure.
Examples
Referring to the attached drawings in the specification, in the embodiment of the invention, an intelligent resin purification system for a hemoperfusion apparatus comprises an hemoperfusion apparatus shell 1, the perfusion device shell 1 is cylindrical and made of medical grade plastics, the upper end and the lower end of the perfusion device shell 1 are respectively detachably connected with an upper cover 2 and a lower cover 3, a connecting shaft 4 is arranged in the perfusion device shell 1, the upper end of the connecting shaft 4 is connected with the upper cover 2, the connecting shaft 4 rotates relative to the perfusion device shell 1, a plurality of movable resin discs 5 are fixedly arranged on the periphery of the connecting shaft 4, a plurality of fixed resin discs 6 are fixedly arranged on the inner wall of the perfusion device shell 1, the movable resin discs 5 and the fixed resin discs 6 are arranged at intervals in the vertical direction, a plurality of resin adsorption areas 8 are uniformly arranged on the movable resin disc 5 and the fixed resin disc 6 at intervals, and a resin adsorption plate 7 is fixedly arranged at the bottom end inside the perfusion device shell 1.
Further, the upper cover 2 includes a connecting sleeve 201, a movable cover 202 and a sealing ring 203, the connecting sleeve 201 is detachably connected to the perfusion device shell 1, the movable cover 202 is arranged at the upper end of the connecting sleeve 201, the sealing ring 203 is arranged between the connecting sleeve 201 and the movable cover 202, and the connecting shaft 4 is fixedly connected to the movable cover 202.
Further, the inner wall of the connecting sleeve 201 is provided with an internal thread, the outer wall of the upper end of the perfusion device shell 1 is provided with an external thread, and the connecting sleeve 201 is detachably connected to the upper end of the perfusion device shell 1 through a threaded connection.
Further, an avoiding hole 9 for the connecting shaft 4 to pass through is formed in the center of the fixed resin disc 6.
Further, the material of the perfusion device shell 1 is Polycarbonate (PC), Polytetrafluoroethylene (PTFE) or Polyamide (PA).
Further, the resin used in the resin adsorption region 8 of the movable resin plate 5 and the fixed resin plate 6 is ion exchange resin or adsorption resin.
Further, the movable resin tray 5 and the fixed resin tray 6 each include a support frame made of 316 or 317L stainless steel.
The use process comprises the following steps:
when the perfusion device is used, blood enters from the upper end of the perfusion device and flows out after being adsorbed from the lower end, the movable cover 202 is rotated according to the concentration of harmful substances to adjust the relative angle between the movable resin disc 5 and the fixed resin disc 6, the overlapping area of the resin adsorption area 8 on the movable cover 202 and the fixed resin disc is changed, the adsorption quality and the efficiency are considered, and the practicability of the perfusion device is enhanced.
In the process, through the arrangement of the movable resin disc and the fixed resin disc, blood is filtered by the resin adsorption areas arranged in the vertical direction, so that the contact time and the contact area of the blood and the resin are improved, harmful substances in the blood are better removed, and the quality and the efficiency of blood purification are greatly improved; the arrangement that the connecting sleeve in the upper cover and the movable cover can rotate relatively realizes that the relative angle between the movable resin disc and the fixed resin disc is adjusted according to the concentration of harmful substances in blood, reasonably shortens the adsorption time, ensures the adsorption quality and improves the adsorption efficiency; the application has the advantages of simple structure, strong practicability and simple operation and is worth popularizing.
The above is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, it is possible to make several variations and modifications without departing from the concept of the present invention, and these should be considered as the protection scope of the present invention, which will not affect the effect of the implementation of the present invention and the utility of the patent.
In the description of the present invention, it is to be understood that the terms indicating an orientation or positional relationship are based on the orientation or positional relationship shown in the drawings only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.
In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
Claims (7)
1. The utility model provides a resin intelligence clean system for hemoperfusion ware which characterized in that: the perfusion device comprises a perfusion device shell (1), wherein the perfusion device shell (1) is cylindrical and is made of medical grade plastics, an upper cover (2) and a lower cover (3) are detachably connected to the upper end and the lower end of the perfusion device shell (1) respectively, a connecting shaft (4) is arranged in the perfusion device shell (1), the upper end of the connecting shaft (4) is connected with the upper cover (2), the connecting shaft (4) rotates relative to the perfusion device shell (1), a plurality of movable resin discs (5) are fixedly arranged on the periphery of the connecting shaft (4), a plurality of fixed resin discs (6) are fixedly arranged on the inner wall of the perfusion device shell (1), the movable resin discs (5) and the fixed resin discs (6) are arranged in the vertical direction at intervals, and a plurality of resin adsorption areas (8) are uniformly arranged on the movable resin discs (5) and the fixed resin discs (6) at intervals, and a resin adsorption plate (7) is fixedly arranged at the bottom end in the perfusion device shell (1).
2. The intelligent resin purification system for a hemoperfusion apparatus according to claim 1, wherein: the upper cover (2) comprises a connecting sleeve (201), a movable cover (202) and a sealing ring (203), the connecting sleeve (201) is detachably connected with the perfusion device shell (1), the movable cover (202) is arranged at the upper end of the connecting sleeve (201), the sealing ring (203) is arranged between the connecting sleeve (201) and the movable cover (202), and the connecting shaft (4) is fixedly connected with the movable cover (202).
3. The intelligent resin purification system for a hemoperfusion apparatus according to claim 2, wherein: the inner wall of the connecting sleeve (201) is provided with internal threads, the outer wall of the upper end of the perfusion device shell (1) is provided with external threads, and the connecting sleeve (201) is detachably connected to the upper end of the perfusion device shell (1) through threaded connection.
4. The intelligent resin purification system for a hemoperfusion apparatus according to claim 1, wherein: and an avoidance hole (9) for the connecting shaft (4) to pass through is formed in the center of the fixed resin disc (6).
5. The intelligent resin purification system for a hemoperfusion apparatus according to claim 1, wherein: the material of the perfusion device shell (1) is Polycarbonate (PC), Polytetrafluoroethylene (PTFE) or Polyamide (PA).
6. The intelligent resin purification system for a hemoperfusion apparatus according to claim 1, wherein: and the resins used in the resin adsorption areas (8) of the movable resin disc (5) and the fixed resin disc (6) are ion exchange resins or adsorption resins.
7. The intelligent resin purification system for a hemoperfusion apparatus according to claim 1, wherein: the movable resin disc (5) and the fixed resin disc (6) both comprise 316 or 317L stainless steel support frames.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110616644.3A CN113368325B (en) | 2021-05-27 | 2021-05-27 | Resin intelligent purification system for blood perfusion device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110616644.3A CN113368325B (en) | 2021-05-27 | 2021-05-27 | Resin intelligent purification system for blood perfusion device |
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| Publication Number | Publication Date |
|---|---|
| CN113368325A true CN113368325A (en) | 2021-09-10 |
| CN113368325B CN113368325B (en) | 2023-08-01 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202110616644.3A Active CN113368325B (en) | 2021-05-27 | 2021-05-27 | Resin intelligent purification system for blood perfusion device |
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| Country | Link |
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| CN (1) | CN113368325B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112999694A (en) * | 2021-03-24 | 2021-06-22 | 沧州信联化工有限公司 | Raw material refining device for processing tetramethylammonium hydroxide and use method thereof |
Citations (8)
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|---|---|---|---|---|
| JPH06277467A (en) * | 1993-03-29 | 1994-10-04 | Toto Ltd | Rotary flat membrane filter machine |
| JP2011019685A (en) * | 2009-07-15 | 2011-02-03 | Nikkiso Co Ltd | Hemocatharsis column |
| CN204293593U (en) * | 2014-11-03 | 2015-04-29 | 珠海健帆生物科技股份有限公司 | A kind of blood perfusion device |
| CN204428504U (en) * | 2014-12-27 | 2015-07-01 | 珠海健帆生物科技股份有限公司 | A kind of perfusion device drainage stent and perfusion device |
| CN204618991U (en) * | 2014-11-03 | 2015-09-09 | 珠海健帆生物科技股份有限公司 | A kind of blood perfusion device |
| US20170072349A1 (en) * | 2015-09-11 | 2017-03-16 | Ultra Small Fibers, LLC | Tunable nanofiber filter media and filter devices |
| CN209864812U (en) * | 2019-03-19 | 2019-12-31 | 北京中科盛康科技有限公司 | Blood perfusion device |
| CN111957304A (en) * | 2020-08-19 | 2020-11-20 | 上海金成高分子材料有限公司 | Macroporous adsorption resin for blood perfusion and preparation method thereof |
-
2021
- 2021-05-27 CN CN202110616644.3A patent/CN113368325B/en active Active
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06277467A (en) * | 1993-03-29 | 1994-10-04 | Toto Ltd | Rotary flat membrane filter machine |
| JP2011019685A (en) * | 2009-07-15 | 2011-02-03 | Nikkiso Co Ltd | Hemocatharsis column |
| CN204293593U (en) * | 2014-11-03 | 2015-04-29 | 珠海健帆生物科技股份有限公司 | A kind of blood perfusion device |
| CN204618991U (en) * | 2014-11-03 | 2015-09-09 | 珠海健帆生物科技股份有限公司 | A kind of blood perfusion device |
| CN204428504U (en) * | 2014-12-27 | 2015-07-01 | 珠海健帆生物科技股份有限公司 | A kind of perfusion device drainage stent and perfusion device |
| US20170072349A1 (en) * | 2015-09-11 | 2017-03-16 | Ultra Small Fibers, LLC | Tunable nanofiber filter media and filter devices |
| CN209864812U (en) * | 2019-03-19 | 2019-12-31 | 北京中科盛康科技有限公司 | Blood perfusion device |
| CN111957304A (en) * | 2020-08-19 | 2020-11-20 | 上海金成高分子材料有限公司 | Macroporous adsorption resin for blood perfusion and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112999694A (en) * | 2021-03-24 | 2021-06-22 | 沧州信联化工有限公司 | Raw material refining device for processing tetramethylammonium hydroxide and use method thereof |
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| CN113368325B (en) | 2023-08-01 |
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