CN113317395A - 一种高效改善酸化剂功能的组合物及其制备方法 - Google Patents
一种高效改善酸化剂功能的组合物及其制备方法 Download PDFInfo
- Publication number
- CN113317395A CN113317395A CN202110711319.5A CN202110711319A CN113317395A CN 113317395 A CN113317395 A CN 113317395A CN 202110711319 A CN202110711319 A CN 202110711319A CN 113317395 A CN113317395 A CN 113317395A
- Authority
- CN
- China
- Prior art keywords
- parts
- acidifier
- composition
- licochalcone
- tween
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 21
- 239000002535 acidifier Substances 0.000 title claims abstract description 19
- 238000002360 preparation method Methods 0.000 title claims abstract description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 18
- KAZSKMJFUPEHHW-UHFFFAOYSA-N (2E)-3-[5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hdyroxyphenyl)-2-propen-1-one Natural products COC1=CC(O)=C(C(C)(C)C=C)C=C1C=CC(=O)C1=CC=C(O)C=C1 KAZSKMJFUPEHHW-UHFFFAOYSA-N 0.000 claims abstract description 9
- IUCVKTHEUWACFB-UHFFFAOYSA-N Licochalcone A Natural products COC1=CC=C(C(C)(C)C=C)C=C1C=CC(=O)C1=CC=C(O)C=C1 IUCVKTHEUWACFB-UHFFFAOYSA-N 0.000 claims abstract description 9
- KAZSKMJFUPEHHW-DHZHZOJOSA-N Licochalcone A Chemical compound COC1=CC(O)=C(C(C)(C)C=C)C=C1\C=C\C(=O)C1=CC=C(O)C=C1 KAZSKMJFUPEHHW-DHZHZOJOSA-N 0.000 claims abstract description 9
- 229920000136 polysorbate Polymers 0.000 claims abstract description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 7
- USFZMSVCRYTOJT-UHFFFAOYSA-N Ammonium acetate Chemical compound N.CC(O)=O USFZMSVCRYTOJT-UHFFFAOYSA-N 0.000 claims abstract description 6
- 239000005695 Ammonium acetate Substances 0.000 claims abstract description 6
- 239000004475 Arginine Substances 0.000 claims abstract description 6
- 239000004115 Sodium Silicate Substances 0.000 claims abstract description 6
- 235000019257 ammonium acetate Nutrition 0.000 claims abstract description 6
- 229940043376 ammonium acetate Drugs 0.000 claims abstract description 6
- VZTDIZULWFCMLS-UHFFFAOYSA-N ammonium formate Chemical compound [NH4+].[O-]C=O VZTDIZULWFCMLS-UHFFFAOYSA-N 0.000 claims abstract description 6
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims abstract description 6
- 235000019795 sodium metasilicate Nutrition 0.000 claims abstract description 6
- NTHWMYGWWRZVTN-UHFFFAOYSA-N sodium silicate Chemical compound [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 claims abstract description 6
- 229910052911 sodium silicate Inorganic materials 0.000 claims abstract description 6
- 238000003756 stirring Methods 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 5
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims description 3
- 229920001214 Polysorbate 60 Polymers 0.000 claims description 3
- 230000008569 process Effects 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 5
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 4
- 230000000840 anti-viral effect Effects 0.000 abstract description 4
- 239000003674 animal food additive Substances 0.000 abstract description 2
- 239000000872 buffer Substances 0.000 abstract description 2
- 239000007853 buffer solution Substances 0.000 abstract description 2
- 230000006806 disease prevention Effects 0.000 abstract description 2
- 230000036039 immunity Effects 0.000 abstract description 2
- 244000144972 livestock Species 0.000 abstract description 2
- 241001465754 Metazoa Species 0.000 description 8
- 239000003651 drinking water Substances 0.000 description 7
- 235000020188 drinking water Nutrition 0.000 description 7
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 6
- 206010012735 Diarrhoea Diseases 0.000 description 5
- 230000003139 buffering effect Effects 0.000 description 5
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 description 4
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 4
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 4
- 244000000010 microbial pathogen Species 0.000 description 4
- 241000282887 Suidae Species 0.000 description 3
- 238000009395 breeding Methods 0.000 description 3
- 230000001488 breeding effect Effects 0.000 description 3
- 150000007524 organic acids Chemical class 0.000 description 3
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 2
- 235000011054 acetic acid Nutrition 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 235000019253 formic acid Nutrition 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 235000019260 propionic acid Nutrition 0.000 description 2
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 2
- 208000035240 Disease Resistance Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 206010016256 fatigue Diseases 0.000 description 1
- 235000021050 feed intake Nutrition 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 235000012631 food intake Nutrition 0.000 description 1
- 230000027119 gastric acid secretion Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000005416 organic matter Substances 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/28—Silicates, e.g. perlites, zeolites or bentonites
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/111—Aromatic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/121—Heterocyclic compounds containing oxygen or sulfur as hetero atom
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Animal Husbandry (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Birds (AREA)
- Rheumatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Virology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
本发明属于兽用饲料添加剂领域，具体公开一种高效改善酸化剂功能的组合物及其制备方法。以总质量份数之和为100份计，组合物的组成为：偏硅酸钠5‑10份、精氨酸5‑10份、甲酸铵10‑15份、乙酸铵10‑15份、吐温15‑30份、甘油6‑10份、甘草查而酮A 2‑5份，余量为水。本发明提出的组合物为一种弱碱性缓冲体系，当该组合物与酸化剂按1∶15‑30比例混合后即可较大幅度提高酸化剂的缓冲能力，同时甘草查而酮A的应用，可大幅度提高普通酸化剂的防病功能，使普通酸化剂抗菌、抗病毒、提升免疫力的功效大幅度增强；在本发明申请之前，目前尚无该类技术报道。
Description
技术领域
本发明属于兽用饲料添加剂领域，具体涉及一种高效改善酸化剂功能的组合物及其制备方法。
背景技术
生猪和家禽的集约化养殖过程中，因为对综合养殖效益的极限追求，导致高密度、富营养的养殖模式。在这种环境下，动物缺少运动，摄入单一的高蛋白日粮造成动物的亚健康状态，常表现为消化道炎症、消化功能障碍、精神不振进而采食下降，导致生产性能降低。且一旦有病原微生物引入，极易通过饮水传播造成更严重的损失。因此人们发明了酸化剂，在饮水中长期添加，一方面减少饮水中病原微生物的数量，另一方面有机酸可提高动物的采食量，改善幼龄动物胃酸分泌不足的特点，降低饲料的系酸率。
常见的有机酸化剂多由甲酸、乙酸、丙酸、丁酸、乳酸、柠檬酸等组成，具有高效的抑菌效果，并且对提高动物的生产性能以及改善幼龄动物腹泻有较好的效果。但是这种酸化剂存在的问题是：小分子的有机酸在开放环境中易挥发，且缓冲能力有限，当稀释1000倍以上时pH经常会快速升高，达不到应有的抑菌效果。且当饮水线中存在有机质较多时，效果更差。
发明内容
针对上述现有技术的缺陷与不足，本发明的目的在于提供一种高效改善酸化剂功能的组合物及其制备方法。
为实现上述目的，本发明采取的技术方案如下：
一种高效改善酸化剂功能的组合物，以总质量份数之和为100份计，组合物的组成为：偏硅酸钠5-10份、精氨酸 5-10份、甲酸铵10-15份、乙酸铵10-15份、吐温15-30份、甘油6-10份、甘草查而酮A 2-5份，余量为水。
较好地，所述吐温为吐温60。
所述的高效改善酸化剂功能的组合物的制备方法：把偏硅酸钠和精氨酸用水溶解，加入甘油搅拌均匀，再加入甘草查而酮A搅拌至溶解，加入吐温搅拌均匀，再加入甲酸铵、乙酸铵搅拌至溶解均匀即可。
有益效果：本发明提出的组合物为一种弱碱性缓冲体系，当该组合物与酸化剂按1∶15-30比例混合后即可较大幅度提高酸化剂的缓冲能力，同时甘草查而酮A的应用，可大幅度提高普通酸化剂的防病功能，使普通酸化剂抗菌、抗病毒、提升免疫力的功效大幅度增强；在本发明申请之前，目前尚无该类技术报道。
具体实施方式
为使本发明更加清楚、明确，以下对本发明进一步详细说明。应当理解，此处所描述的具体实施例仅仅用以解释本发明，并不用于限定本发明。
实施例1-4
一种高效改善酸化剂功能的组合物，以质量份计，组合物的组成如表1所示。
实施例1-4的制备方法：把偏硅酸钠和精氨酸用水溶解，加入甘油搅拌均匀，再加入甘草查而酮A搅拌至溶解，加入吐温60搅拌均匀，再加入甲酸铵、乙酸铵搅拌至溶解均匀即可。
对复合酸化剂缓冲能力的影响验证
将实施例2制备所得组合物按不同比例与复合酸化剂复配，复配后缓冲能力的变化如表2，所述复合酸化剂的组成为（重量百分比）：甲酸36%、乙酸20%、丙酸10%、丁酸5%、柠檬酸5%，余量为水。
稀释相同倍数，pH值变化越小，缓冲能力越强，由表2可见：当组合物与酸化剂按1∶15-1∶30范围配比，均可有效改善普通酸化剂的缓冲能力。
对复合酸化剂抗病、抗病毒能力的影响
1 试验目的
验证本发明实施例2制备所得组合物对断奶仔猪发生腹泻的预防效果。
2试验方法
2.1试验材料
试验动物：21日龄断奶三元杂交仔猪30栏。
饲料：使用养殖场自配全价料，配方如表3。
2.2试验分组及统计方法
按猪舍走向10栏为1组，分别为空白对照组、阳性对照组、本发明组，各组用药方法见表5。
表5 各组用药方法
2.3 观察指标
腹泻率=试验30天内发生腹泻的仔猪头数/组内总头数；
30天内日均增重=试验结束时均重/试验开始时均重；
死亡率=试验过程中死亡头数/组内总头数*100%。
2.4试验结果
各组试验结果见下表6。
2.7 小结及分析
按1∶20的重量比把本发明组合物与普通复合酸化剂复配后，按比例将1L复配酸化剂添加入1吨断奶仔猪的饮水中自由饮用，可有效降低断奶仔猪的腹泻率，并提高日增重，降低死亡率。产生以上效果的原因，一方面是通过降低饮水pH值从而减少饮水中病原微生物的数量，减少感染发病的几率；另一方面不断摄入本品中微量的甘草查而酮A而使动物在优化生理机能的基础上具备更好的免疫机能，表现出优秀的抗炎、抗病毒能力。
Claims (3)
1.一种高效改善酸化剂功能的组合物，其特征在于，以总质量份数之和为100份计，组合物的组成为：偏硅酸钠5-10份、精氨酸 5-10份、甲酸铵10-15份、乙酸铵10-15份、吐温15-30份、甘油6-10份、甘草查而酮A 2-5份，余量为水。
2.如权利要求1所述的高效改善酸化剂功能的组合物，其特征在于：所述吐温为吐温60。
3.一种如权利要求1或2所述的高效改善酸化剂功能的组合物的制备方法，其特征在于：把偏硅酸钠和精氨酸用水溶解，加入甘油搅拌均匀，再加入甘草查而酮A搅拌至溶解，加入吐温搅拌均匀，再加入甲酸铵、乙酸铵搅拌至溶解均匀即可。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110711319.5A CN113317395A (zh) | 2021-06-25 | 2021-06-25 | 一种高效改善酸化剂功能的组合物及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110711319.5A CN113317395A (zh) | 2021-06-25 | 2021-06-25 | 一种高效改善酸化剂功能的组合物及其制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113317395A true CN113317395A (zh) | 2021-08-31 |
Family
ID=77424694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110711319.5A Pending CN113317395A (zh) | 2021-06-25 | 2021-06-25 | 一种高效改善酸化剂功能的组合物及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113317395A (zh) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020098205A1 (en) * | 2000-11-23 | 2002-07-25 | Choi Soo-Il | Composition of multipurpose high functional alkaline solution composition, preparation thereof, and for the use of nonspecific immunostimulator |
| CN105831427A (zh) * | 2016-03-24 | 2016-08-10 | 广州格雷特生物科技有限公司 | 缓释微囊包被复合维生素预混合饲料及其制备方法和应用 |
| CN110679594A (zh) * | 2019-11-22 | 2020-01-14 | 湖南加农正和生物技术有限公司 | 一种复合酸化剂及其制备方法和应用 |
-
2021
- 2021-06-25 CN CN202110711319.5A patent/CN113317395A/zh active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020098205A1 (en) * | 2000-11-23 | 2002-07-25 | Choi Soo-Il | Composition of multipurpose high functional alkaline solution composition, preparation thereof, and for the use of nonspecific immunostimulator |
| CN105831427A (zh) * | 2016-03-24 | 2016-08-10 | 广州格雷特生物科技有限公司 | 缓释微囊包被复合维生素预混合饲料及其制备方法和应用 |
| CN110679594A (zh) * | 2019-11-22 | 2020-01-14 | 湖南加农正和生物技术有限公司 | 一种复合酸化剂及其制备方法和应用 |
Non-Patent Citations (1)
| Title |
|---|
| 谢子任: "甘草药理活性的研究", 《中国实用医药》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102187945B (zh) | 一种平衡动物胃肠道健康的添加剂 | |
| WO2019233496A1 (zh) | 肉桂醛和/或尿囊素在替代乳仔猪饲料中高锌的应用及饲料添加剂或添加剂预混料、饲料 | |
| CN103504137A (zh) | 一种肠溶包被型饲料酸化剂及其制备方法 | |
| CN104187007B (zh) | 一种无抗生素的乳猪配合饲料及其用途 | |
| CN110679594A (zh) | 一种复合酸化剂及其制备方法和应用 | |
| CN1615725A (zh) | 饲料添加用酸化剂 | |
| CN104585507A (zh) | 一种饲用绿色益生型酸化剂及其制备方法 | |
| CN110583890A (zh) | 一种无抗生素的半湿乳猪饲料 | |
| CN109393187A (zh) | 一种抗腹泻的猪饲料添加剂及其制备方法与应用 | |
| CN113287688A (zh) | 一种无抗仔猪保育配合饲料及其制备方法 | |
| CN113317395A (zh) | 一种高效改善酸化剂功能的组合物及其制备方法 | |
| CN104171364A (zh) | 一种提高仔猪日增重的复合寡糖饲料添加剂 | |
| CN114304413B (zh) | 一种含酸化剂的复合物及其制备方法 | |
| CN114223785A (zh) | 一种含低聚木糖的添加剂及制备方法 | |
| CN107095056A (zh) | 用在母猪妊娠期及哺乳期的饲料添加剂 | |
| CN111011634A (zh) | 一种预防断奶仔猪腹泻的猪饲料添加剂及猪饲料 | |
| CN103734466B (zh) | 一种仔猪前期配合饲料 | |
| CN110140820A (zh) | 一种围产期母猪营养强化剂及其制备方法和应用 | |
| CN112641001A (zh) | 一种替抗包衣复合酸化剂 | |
| KR20220061356A (ko) | 치즈 부산물을 이용한 기능성 사료 첨가제 | |
| CN110574837A (zh) | 丹皮酚在替代乳仔猪饲料中高锌的应用及饲料添加剂或添加剂预混料、饲料 | |
| CN106260620B (zh) | 一种新型反刍动物专用生物制剂产品及其制备方法 | |
| CN104171710A (zh) | 一种凝结芽孢杆菌复合饲料添加剂 | |
| CN112219946B (zh) | 一种用于乳猪防疫的复合微生态制剂 | |
| CN112641002B (zh) | 一种添加替抗包衣复合酸化剂的饲料组合物 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210831 |